Publications by authors named "Lois E H Smith"

100Publications

Vitreous metabolomics profiling of proliferative diabetic retinopathy.

Diabetologia 2020 Oct 25. Epub 2020 Oct 25.

Department of Ophthalmology, Tokyo Medical University Hospital, Tokyo, Japan.

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http://dx.doi.org/10.1007/s00125-020-05309-yDOI Listing
October 2020

Notice of Withdrawal: Retinal Vasculature in Development and Diseases.

Annu Rev Vis Sci 2020 10 15;0. Epub 2020 Oct 15.

Department of Ophthalmology, Harvard Medical School, Boston Children's Hospital, Boston, Massachusetts 02115, USA; email:

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http://dx.doi.org/10.1146/annurev-vs-04-091720-200001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7607514PMC
October 2020

An Ex Vivo Choroid Sprouting Assay of Ocular Microvascular Angiogenesis.

J Vis Exp 2020 08 6(162). Epub 2020 Aug 6.

Department of Ophthalmology, Boston Children's Hospital, Harvard Medical School;

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http://dx.doi.org/10.3791/61677DOI Listing
August 2020

Validation of the Retinopathy of Prematurity Activity Scale (ROP-ActS) using retrospective clinical data.

Acta Ophthalmol 2020 Jun 26. Epub 2020 Jun 26.

Department of Ophthalmology, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

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http://dx.doi.org/10.1111/aos.14532DOI Listing
June 2020

Association between low fatty acid levels and platelet count in infants with Retinopathy of Prematurity.

Acta Paediatr 2020 Dec 29;109(12):2547-2548. Epub 2020 Jun 29.

Section for Ophthalmology, Department of Clinical Neuroscience, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

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http://dx.doi.org/10.1111/apa.15406DOI Listing
December 2020

Free fatty acid receptor 4 activation protects against choroidal neovascularization in mice.

Angiogenesis 2020 08 5;23(3):385-394. Epub 2020 Mar 5.

Department of Ophthalmology, Boston Children's Hospital, Harvard Medical School, 300 Longwood Ave, Boston, MA, 02115, USA.

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http://dx.doi.org/10.1007/s10456-020-09717-xDOI Listing
August 2020

Targeting Neurovascular Interaction in Retinal Disorders.

Int J Mol Sci 2020 Feb 22;21(4). Epub 2020 Feb 22.

Department of Ophthalmology, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.3390/ijms21041503DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7073081PMC
February 2020

Sphingosine 1-Phosphate Receptor Signaling Establishes AP-1 Gradients to Allow for Retinal Endothelial Cell Specialization.

Dev Cell 2020 03 13;52(6):779-793.e7. Epub 2020 Feb 13.

Vascular Biology Program, Boston Children's Hospital, Department of Surgery, Harvard Medical School, Boston, MA, USA; Broad Institute of MIT and Harvard, Cambridge, MA, USA; Dana-Farber Cancer Institute, Boston, MA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.devcel.2020.01.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7541081PMC
March 2020

Long-Acting FGF21 Inhibits Retinal Vascular Leakage in In Vivo and In Vitro Models.

Int J Mol Sci 2020 Feb 11;21(4). Epub 2020 Feb 11.

Department of Ophthalmology, Boston Children's Hospital, Harvard Medical School, 300 Longwood Ave, Boston, MA 02115, USA.

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http://dx.doi.org/10.3390/ijms21041188DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072824PMC
February 2020

Pathophysiology of Diabetic Retinopathy: Contribution and Limitations of Laboratory Research.

Ophthalmic Res 2019 30;62(4):196-202. Epub 2019 Jul 30.

Department of Ophthalmology, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1159/000500026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6872907PMC
January 2020

Leucocytosis is associated with retinopathy of prematurity in extremely preterm infants.

Acta Paediatr 2019 07 12;108(7):1357-1358. Epub 2019 Apr 12.

Section for Ophthalmology, Department of Clinical Neuroscience, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

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http://dx.doi.org/10.1111/apa.14798DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6961562PMC
July 2019

Tailored vs Static Oxygen Saturation Targets to Prevent Retinopathy of Prematurity.

JAMA Ophthalmol 2019 04;137(4):423-424

Department of Ophthalmology, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1001/jamaophthalmol.2018.6940DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6961564PMC
April 2019

Review shows that donor milk does not promote the growth and development of preterm infants as well as maternal milk.

Acta Paediatr 2019 06 25;108(6):998-1007. Epub 2019 Jan 25.

Department of Ophthalmology, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

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http://doi.wiley.com/10.1111/apa.14702
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http://dx.doi.org/10.1111/apa.14702DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520191PMC
June 2019

Erythropoietin serum levels, versus anaemia as risk factors for severe retinopathy of prematurity.

Pediatr Res 2019 08 18;86(2):276-282. Epub 2018 Sep 18.

Section for Ophthalmology, Department of Clinical Neuroscience, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

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http://www.nature.com/articles/s41390-018-0186-6
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http://dx.doi.org/10.1038/s41390-018-0186-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6422731PMC
August 2019

Retinal Vasculature in Development and Diseases.

Annu Rev Vis Sci 2018 09;4:101-122

Department of Ophthalmology, Harvard Medical School, Boston Children's Hospital, Boston, Massachusetts 02115, USA; email:

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https://www.annualreviews.org/doi/10.1146/annurev-vision-091
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http://dx.doi.org/10.1146/annurev-vision-091517-034018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326083PMC
September 2018

Consensus guidelines for the use and interpretation of angiogenesis assays.

Angiogenesis 2018 08;21(3):425-532

Angiogenesis Laboratory, Department of Medical Oncology, VU University Medical Center, Cancer Center Amsterdam, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1007/s10456-018-9613-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237663PMC
August 2018

Influence of Human Milk and Parenteral Lipid Emulsions on Serum Fatty Acid Profiles in Extremely Preterm Infants.

JPEN J Parenter Enteral Nutr 2019 01 21;43(1):152-161. Epub 2018 Apr 21.

Section for Ophthalmology, Department of Clinical Neuroscience, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

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http://dx.doi.org/10.1002/jpen.1172DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437763PMC
January 2019

Long-chain polyunsaturated fatty acids decline rapidly in milk from mothers delivering extremely preterm indicating the need for supplementation.

Acta Paediatr 2018 06 13;107(6):1020-1027. Epub 2018 Mar 13.

Section for Ophthalmology, Department of Clinical Neuroscience, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

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http://dx.doi.org/10.1111/apa.14275DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5969106PMC
June 2018

Association of Retinopathy of Prematurity With Low Levels of Arachidonic Acid: A Secondary Analysis of a Randomized Clinical Trial.

JAMA Ophthalmol 2018 03;136(3):271-277

Section of Ophthalmology, Department of Clinical Neuroscience, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Göteborg, Sweden.

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http://dx.doi.org/10.1001/jamaophthalmol.2017.6658DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5885898PMC
March 2018

PPARα is essential for retinal lipid metabolism and neuronal survival.

BMC Biol 2017 Nov 28;15(1):113. Epub 2017 Nov 28.

Department of Physiology, University of Oklahoma Health Sciences Center, 941 Stanton L. Young Blvd., BSEB 328B, Oklahoma City, OK, 73104, USA.

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http://dx.doi.org/10.1186/s12915-017-0451-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706156PMC
November 2017

Retinal energy demands control vascular supply of the retina in development and disease: The role of neuronal lipid and glucose metabolism.

Prog Retin Eye Res 2018 05 22;64:131-156. Epub 2017 Nov 22.

Department of Ophthalmology, Harvard Medical School, Boston Children's Hospital, 300 Longwood Avenue, Boston MA 02115, United States. Electronic address:

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http://dx.doi.org/10.1016/j.preteyeres.2017.11.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5963988PMC
May 2018

IGF-1 as a Drug for Preterm Infants: A Step-Wise Clinical Development.

Curr Pharm Des 2017 ;23(38):5964-5970

Department of Ophthalmology, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

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http://dx.doi.org/10.2174/1381612823666171002114545DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824464PMC
June 2019

Implementing higher oxygen saturation targets reduced the impact of poor weight gain as a predictor for retinopathy of prematurity.

Acta Paediatr 2018 05 20;107(5):767-773. Epub 2017 Sep 20.

Section for Ophthalmology, Department of Clinical Neuroscience, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

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http://dx.doi.org/10.1111/apa.14049DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5837939PMC
May 2018

Sema3f Protects Against Subretinal Neovascularization In Vivo.

EBioMedicine 2017 Apr 21;18:281-287. Epub 2017 Mar 21.

Eye Center, Medical Center, Faculty of Medicine, University of Freiburg, Killianstrasse 5, 79106 Freiburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2017.03.026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5405173PMC
April 2017

Special Commentary: Early Clinical Development of Cell Replacement Therapy: Considerations for the National Eye Institute Audacious Goals Initiative.

Ophthalmology 2017 07 29;124(7):926-934. Epub 2017 Mar 29.

Department of Ophthalmology, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1016/j.ophtha.2017.02.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5483186PMC
July 2017

IGF-1 in retinopathy of prematurity, a CNS neurovascular disease.

Early Hum Dev 2016 11 17;102:13-19. Epub 2016 Sep 17.

Department of Ophthalmology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA. Electronic address:

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085844PMC
http://dx.doi.org/10.1016/j.earlhumdev.2016.09.008DOI Listing
November 2016

IGF-I in the clinics: Use in retinopathy of prematurity.

Growth Horm IGF Res 2016 Oct - Dec;30-31:75-80. Epub 2016 Sep 28.

Section for Ophthalmology, Department of Clinical Neuroscience and Rehabilitation, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Göteborg, Sweden.

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http://dx.doi.org/10.1016/j.ghir.2016.09.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5154870PMC
January 2018

Fenofibrate Inhibits Cytochrome P450 Epoxygenase 2C Activity to Suppress Pathological Ocular Angiogenesis.

EBioMedicine 2016 Nov 30;13:201-211. Epub 2016 Sep 30.

Department of Ophthalmology, Boston Children's Hospital, Harvard Medical School, Boston, MA 01248, United States. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2016.09.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5264653PMC
November 2016

Role of Insulinlike Growth Factor 1 in Fetal Development and in the Early Postnatal Life of Premature Infants.

Am J Perinatol 2016 09 7;33(11):1067-71. Epub 2016 Sep 7.

Department of Ophthalmology, Institute of Neuroscience and Physiology, University of Gothenburg, Gothenburg, Sweden.

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http://dx.doi.org/10.1055/s-0036-1586109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5779855PMC
September 2016

Neurovascular cross talk in diabetic retinopathy: Pathophysiological roles and therapeutic implications.

Am J Physiol Heart Circ Physiol 2016 09 29;311(3):H738-49. Epub 2016 Jul 29.

Depatment of Physiology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma; Harold Hamm Diabetes Center, Oklahoma City, Oklahoma;

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http://dx.doi.org/10.1152/ajpheart.00005.2016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5142179PMC
September 2016

Cytochrome P450 Oxidase 2C Inhibition Adds to ω-3 Long-Chain Polyunsaturated Fatty Acids Protection Against Retinal and Choroidal Neovascularization.

Arterioscler Thromb Vasc Biol 2016 09 14;36(9):1919-27. Epub 2016 Jul 14.

From the Department of Ophthalmology, Boston Children's Hospital, Harvard Medical School, MA (Y.G., Z.F., C.-H.L., Z.W., Z.S., T.W.F., N.J.S., P.C.M., S.B.B., S.S.M., E.P.M., L.E.H.S.); Division of Intramural Research, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC (M.L.E., F.B.L., D.C.Z.); Department of Entomology and Comprehensive Cancer Center, University of California, Davis (K.S.S.L., B.D.H.); Section on Nutritional Neurosciences in the Laboratory of Membrane Biophysics and Biochemistry, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD (J.P.S.G.); and Department of Ophthalmology, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden (A.H.).

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https://www.ahajournals.org/doi/10.1161/ATVBAHA.116.307558
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http://dx.doi.org/10.1161/ATVBAHA.116.307558DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5010176PMC
September 2016

Review: adiponectin in retinopathy.

Biochim Biophys Acta 2016 08 4;1862(8):1392-400. Epub 2016 May 4.

Department of Ophthalmology, Boston Children's Hospital, Harvard Medical School, Boston, MA, United States. Electronic address:

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http://dx.doi.org/10.1016/j.bbadis.2016.05.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4885769PMC
August 2016

The Eyes Absent Proteins in Developmental and Pathological Angiogenesis.

Am J Pathol 2016 Mar 5;186(3):568-78. Epub 2016 Jan 5.

Division of Developmental Biology, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, Ohio. Electronic address:

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http://dx.doi.org/10.1016/j.ajpath.2015.10.031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4816707PMC
March 2016

SOCS3 in retinal neurons and glial cells suppresses VEGF signaling to prevent pathological neovascular growth.

Sci Signal 2015 Sep 22;8(395):ra94. Epub 2015 Sep 22.

Department of Ophthalmology, Harvard Medical School, Boston Children's Hospital, 300 Longwood Avenue, Boston, MA 02115, USA.

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http://dx.doi.org/10.1126/scisignal.aaa8695DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4659437PMC
September 2015

Optimization of an Image-Guided Laser-Induced Choroidal Neovascularization Model in Mice.

PLoS One 2015 10;10(7):e0132643. Epub 2015 Jul 10.

Department of Ophthalmology, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0132643PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4498645PMC
April 2016

Netrin-1 - DCC Signaling Systems and Age-Related Macular Degeneration.

PLoS One 2015 7;10(5):e0125548. Epub 2015 May 7.

Analytic & Translational Genetics Unit, Center for Human Genetic Research, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0125548PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4423995PMC
April 2016

Dietary ω-3 polyunsaturated fatty acids decrease retinal neovascularization by adipose-endoplasmic reticulum stress reduction to increase adiponectin.

Am J Clin Nutr 2015 Apr 4;101(4):879-88. Epub 2015 Feb 4.

From the Department of Ophthalmology, Boston Children's Hospital, Harvard Medical School, Boston, MA (ZF, ZS, YS, J-SJ, CGH, RZC, LPE, KT, JC, and LEHS); the Department of Ophthalmology, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden (CAL and AH); the Department of Pediatrics, Institute of Clinical Sciences Lund, Lund University and Skåne University Hospital, Lund, Sweden (DL and IHP); and National Eye Institute, Division of Epidemiology and Clinical Research Clinical Trials Branch, National Eye Institute, NIH, Bethesda, MD (JPS).

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http://dx.doi.org/10.3945/ajcn.114.099291DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381778PMC
April 2015

Insulin-like growth factor-1 and anti-vascular endothelial growth factor in retinopathy of prematurity: has the time come?

Neonatology 2014 5;106(3):254-60. Epub 2014 Oct 5.

Eye Center, University of Freiburg, Freiburg, Germany.

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http://dx.doi.org/10.1159/000365132DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4197141PMC
June 2015

Weight at first detection of retinopathy of prematurity predicts disease severity.

Br J Ophthalmol 2014 Nov 24;98(11):1565-9. Epub 2014 Jun 24.

Institute of Neuroscience and Physiology, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden.

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http://dx.doi.org/10.1136/bjophthalmol-2014-304905DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4389626PMC
November 2014

Cytochrome P450 2C8 ω3-long-chain polyunsaturated fatty acid metabolites increase mouse retinal pathologic neovascularization--brief report.

Arterioscler Thromb Vasc Biol 2014 Mar 23;34(3):581-6. Epub 2014 Jan 23.

From the Department of Ophthalmology, Boston Children's Hospital (Z.S., Z.F., J.-S.J., C. Hatton, A.J., C. Hurst, L.E., Z.C., D.P., Y.G., D.X., K.T., H.B., J.C., L.E.H.S.) and Department of Pathology, Beth Israel Deaconess Medical Center (D.P.), Harvard Medical School, Boston, MA; University Eye Hospital Freiburg, Freiburg, Germany (A.S.); Division of Intramural Research, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina, NC (M.L.E., F.L., D.C.Z.); Department of Ophthalmology, Hôpital Maisonneuve-Rosemont, University of Montreal, Montreal, Quebec, Canada (P.S.); and Department of Ophthalmology, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden (A.H.).

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http://dx.doi.org/10.1161/ATVBAHA.113.302927DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4005334PMC
March 2014

Sirtuin1 over-expression does not impact retinal vascular and neuronal degeneration in a mouse model of oxygen-induced retinopathy.

PLoS One 2014 8;9(1):e85031. Epub 2014 Jan 8.

Department of Ophthalmology, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America ; Manton Center for Orphan Disease Research, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0085031PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3885684PMC
September 2014

Retinopathy of prematurity.

Lancet 2013 Oct 17;382(9902):1445-57. Epub 2013 Jun 17.

Department of Ophthalmology, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Göteborg, Sweden.

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http://dx.doi.org/10.1016/S0140-6736(13)60178-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4389630PMC
October 2013

Altered cholesterol homeostasis in aged macrophages linked to neovascular macular degeneration.

Cell Metab 2013 Apr;17(4):471-2

Department of Ophthalmology, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1016/j.cmet.2013.03.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3669899PMC
April 2013

Protective inflammasome activation in AMD.

Nat Med 2012 May 4;18(5):658-60. Epub 2012 May 4.

Department of Ophthalmology, Children's Hospital Boston, Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1038/nm.2761DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3687521PMC
May 2012

Propranolol inhibition of β-adrenergic receptor does not suppress pathologic neovascularization in oxygen-induced retinopathy.

Invest Ophthalmol Vis Sci 2012 May 17;53(6):2968-77. Epub 2012 May 17.

Department of Ophthalmology, Harvard Medical School, Children's Hospital Boston, Massachusetts, USA.

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http://dx.doi.org/10.1167/iovs.12-9691DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3376075PMC
May 2012

Restraint of angiogenesis by zinc finger transcription factor CTCF-dependent chromatin insulation.

Proc Natl Acad Sci U S A 2011 Sep 6;108(37):15231-6. Epub 2011 Sep 6.

Department of Biochemistry and Molecular Biology, University of Florida College of Medicine, Gainesville, FL 32610-3633, USA.

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http://dx.doi.org/10.1073/pnas.1104662108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3174592PMC
September 2011

Lipid metabolites in the pathogenesis and treatment of neovascular eye disease.

Br J Ophthalmol 2011 Nov 18;95(11):1496-501. Epub 2011 Mar 18.

Department of Ophthalmology, Harvard Medical School, Children's Hospital, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1136/bjo.2010.194241DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3711020PMC
November 2011

Resveratrol inhibits pathologic retinal neovascularization in Vldlr(-/-) mice.

Invest Ophthalmol Vis Sci 2011 Apr 25;52(5):2809-16. Epub 2011 Apr 25.

Department of Ophthalmology, Harvard Medical School, Children's Hospital, Boston, Massachusetts 02115, USA

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http://dx.doi.org/10.1167/iovs.10-6496DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3088563PMC
April 2011

An eye for discovery.

J Clin Invest 2010 Sep 1;120(9):3008-11. Epub 2010 Sep 1.

Department of Ophthalmology, Children’s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1172/JCI44158DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2929742PMC
September 2010

Moderate GSK-3β inhibition improves neovascular architecture, reduces vascular leakage, and reduces retinal hypoxia in a model of ischemic retinopathy.

Angiogenesis 2010 Sep 1;13(3):269-77. Epub 2010 Sep 1.

Department of Pathology and Center for Vascular Biology Research, Beth Israel Deaconess Medical Center and Harvard Medical School, 99 Brookline Avenue, Boston, MA 02215, USA.

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http://dx.doi.org/10.1007/s10456-010-9184-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3077563PMC
September 2010

Calpain inhibitors reduce retinal hypoxia in ischemic retinopathy by improving neovascular architecture and functional perfusion.

Biochim Biophys Acta 2011 Apr 8;1812(4):549-57. Epub 2010 Sep 8.

Department of Pathology and Center for Vascular Biology Research, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02215, USA.

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http://dx.doi.org/10.1016/j.bbadis.2010.08.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3005970PMC
April 2011

High or low oxygen saturation and severe retinopathy of prematurity: a meta-analysis.

Pediatrics 2010 Jun 24;125(6):e1483-92. Epub 2010 May 24.

Division of Newborn Medicine, Floating Hospital for Children at Tufts Medical Center, Box 854, 800 Washington St, Boston, MA 02111-1526, USA.

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http://dx.doi.org/10.1542/peds.2009-2218DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4016714PMC
June 2010

The mouse retina as an angiogenesis model.

Invest Ophthalmol Vis Sci 2010 Jun;51(6):2813-26

Department of Ophthalmology, Harvard Medical School, Children's Hospital Boston, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1167/iovs.10-5176DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2891451PMC
June 2010

Longitudinal postnatal weight measurements for the prediction of retinopathy of prematurity.

Arch Ophthalmol 2010 Apr;128(4):443-7

Department of Ophthalmology, Children's Hospital Boston, Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1001/archophthalmol.2010.31DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4393744PMC
April 2010

Validation of a new retinopathy of prematurity screening method monitoring longitudinal postnatal weight and insulinlike growth factor I.

Arch Ophthalmol 2009 May;127(5):622-7

Section of Pediatric Ophthalmology, The Queen Silvia Children's Hospital, Sahlgrenska Academy at University of Gothenburg, Göteborg, Sweden.

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http://dx.doi.org/10.1001/archophthalmol.2009.69DOI Listing
May 2009

Emerging treatments for retinopathy of prematurity.

Semin Ophthalmol 2009 Mar-Apr;24(2):82-6

Department of Ophthalmology, Children's Hospital Boston, Boston, MA 02115, USA.

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http://dx.doi.org/10.1080/08820530902800322DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4028623PMC
May 2009

A mechanosensitive transcriptional mechanism that controls angiogenesis.

Nature 2009 Feb;457(7233):1103-8

Vascular Biology Program, Department of Pathology & Surgery, Children's Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA.

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http://www.nature.com/articles/nature07765
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http://dx.doi.org/10.1038/nature07765DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2708674PMC
February 2009

Quantification and localization of the IGF/insulin system expression in retinal blood vessels and neurons during oxygen-induced retinopathy in mice.

Invest Ophthalmol Vis Sci 2009 Apr 7;50(4):1831-7. Epub 2008 Nov 7.

Department of Ophthalmology, Institute of Neuroscience and Physiology, University of Gothenburg, Gothenburg, Sweden.

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http://dx.doi.org/10.1167/iovs.08-2903DOI Listing
April 2009

Suppression of retinal neovascularization by erythropoietin siRNA in a mouse model of proliferative retinopathy.

Invest Ophthalmol Vis Sci 2009 Mar 24;50(3):1329-35. Epub 2008 Oct 24.

Department of Ophthalmology, Children's Hospital Boston, Harvard Medical School, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1167/iovs.08-2521DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2892257PMC
March 2009

Through the eyes of a child: understanding retinopathy through ROP the Friedenwald lecture.

Authors:
Lois E H Smith

Invest Ophthalmol Vis Sci 2008 Dec 15;49(12):5177-82. Epub 2008 Aug 15.

Children's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA. .

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http://dx.doi.org/10.1167/iovs.08-2584DOI Listing
December 2008