Lloyd A Greene

Lloyd A Greene

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Lloyd A Greene

Lloyd A Greene

Publications by authors named "Lloyd A Greene"

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63Publications

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Dominant-Negative ATF5 Compromises Cancer Cell Survival by Targeting CEBPB and CEBPD.

Mol Cancer Res 2019 Nov 1. Epub 2019 Nov 1.

Pathology and Cell Biology, Columbia University Medical Center

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http://dx.doi.org/10.1158/1541-7786.MCR-19-0631DOI Listing
November 2019

Dominant-negative ATF5 rapidly depletes survivin in tumor cells.

Cell Death Dis 2019 Sep 24;10(10):709. Epub 2019 Sep 24.

Department of Pathology and Cell Biology, Columbia University, New York, NY, 10032, USA.

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http://dx.doi.org/10.1038/s41419-019-1872-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6760124PMC
September 2019

Stress-induced phospho-ubiquitin formation causes parkin degradation.

Sci Rep 2019 Aug 12;9(1):11682. Epub 2019 Aug 12.

Department of Pathology and Cell Biology, Columbia University Medical Center, New York, NY, USA.

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http://dx.doi.org/10.1038/s41598-019-47952-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6690910PMC
August 2019

Context-dependent expression of a conditionally-inducible form of active Akt.

PLoS One 2018 19;13(6):e0197899. Epub 2018 Jun 19.

Department of Pathology and Cell Biology, Columbia University Medical Center, New York, New York, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0197899PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6007834PMC
December 2018

Activating Transcription Factor 4 (ATF4) Regulates Neuronal Activity by Controlling GABAR Trafficking.

J Neurosci 2018 07 6;38(27):6102-6113. Epub 2018 Jun 6.

Department of Pathology & Cell Biology and the Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Medical Center, New York, New York 10033

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http://dx.doi.org/10.1523/JNEUROSCI.3350-17.2018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6596153PMC
July 2018

Guanabenz promotes neuronal survival via enhancement of ATF4 and parkin expression in models of Parkinson disease.

Exp Neurol 2018 05 9;303:95-107. Epub 2018 Feb 9.

Department of Neurology, Columbia University College of Physicians and Surgeons, New York, NY, USA. Electronic address:

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http://dx.doi.org/10.1016/j.expneurol.2018.01.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5864566PMC
May 2018

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.

Authors:
Lorenzo Galluzzi Ilio Vitale Stuart A Aaronson John M Abrams Dieter Adam Patrizia Agostinis Emad S Alnemri Lucia Altucci Ivano Amelio David W Andrews Margherita Annicchiarico-Petruzzelli Alexey V Antonov Eli Arama Eric H Baehrecke Nickolai A Barlev Nicolas G Bazan Francesca Bernassola Mathieu J M Bertrand Katiuscia Bianchi Mikhail V Blagosklonny Klas Blomgren Christoph Borner Patricia Boya Catherine Brenner Michelangelo Campanella Eleonora Candi Didac Carmona-Gutierrez Francesco Cecconi Francis K-M Chan Navdeep S Chandel Emily H Cheng Jerry E Chipuk John A Cidlowski Aaron Ciechanover Gerald M Cohen Marcus Conrad Juan R Cubillos-Ruiz Peter E Czabotar Vincenzo D'Angiolella Ted M Dawson Valina L Dawson Vincenzo De Laurenzi Ruggero De Maria Klaus-Michael Debatin Ralph J DeBerardinis Mohanish Deshmukh Nicola Di Daniele Francesco Di Virgilio Vishva M Dixit Scott J Dixon Colin S Duckett Brian D Dynlacht Wafik S El-Deiry John W Elrod Gian Maria Fimia Simone Fulda Ana J García-Sáez Abhishek D Garg Carmen Garrido Evripidis Gavathiotis Pierre Golstein Eyal Gottlieb Douglas R Green Lloyd A Greene Hinrich Gronemeyer Atan Gross Gyorgy Hajnoczky J Marie Hardwick Isaac S Harris Michael O Hengartner Claudio Hetz Hidenori Ichijo Marja Jäättelä Bertrand Joseph Philipp J Jost Philippe P Juin William J Kaiser Michael Karin Thomas Kaufmann Oliver Kepp Adi Kimchi Richard N Kitsis Daniel J Klionsky Richard A Knight Sharad Kumar Sam W Lee John J Lemasters Beth Levine Andreas Linkermann Stuart A Lipton Richard A Lockshin Carlos López-Otín Scott W Lowe Tom Luedde Enrico Lugli Marion MacFarlane Frank Madeo Michal Malewicz Walter Malorni Gwenola Manic Jean-Christophe Marine Seamus J Martin Jean-Claude Martinou Jan Paul Medema Patrick Mehlen Pascal Meier Sonia Melino Edward A Miao Jeffery D Molkentin Ute M Moll Cristina Muñoz-Pinedo Shigekazu Nagata Gabriel Nuñez Andrew Oberst Moshe Oren Michael Overholtzer Michele Pagano Theocharis Panaretakis Manolis Pasparakis Josef M Penninger David M Pereira Shazib Pervaiz Marcus E Peter Mauro Piacentini Paolo Pinton Jochen H M Prehn Hamsa Puthalakath Gabriel A Rabinovich Markus Rehm Rosario Rizzuto Cecilia M P Rodrigues David C Rubinsztein Thomas Rudel Kevin M Ryan Emre Sayan Luca Scorrano Feng Shao Yufang Shi John Silke Hans-Uwe Simon Antonella Sistigu Brent R Stockwell Andreas Strasser Gyorgy Szabadkai Stephen W G Tait Daolin Tang Nektarios Tavernarakis Andrew Thorburn Yoshihide Tsujimoto Boris Turk Tom Vanden Berghe Peter Vandenabeele Matthew G Vander Heiden Andreas Villunger Herbert W Virgin Karen H Vousden Domagoj Vucic Erwin F Wagner Henning Walczak David Wallach Ying Wang James A Wells Will Wood Junying Yuan Zahra Zakeri Boris Zhivotovsky Laurence Zitvogel Gerry Melino Guido Kroemer

Cell Death Differ 2018 03 23;25(3):486-541. Epub 2018 Jan 23.

Paris Descartes/Paris V University, Paris, France.

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http://dx.doi.org/10.1038/s41418-017-0012-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5864239PMC
March 2018

Brain-Derived Neurotrophic Factor Elevates Activating Transcription Factor 4 (ATF4) in Neurons and Promotes ATF4-Dependent Induction of .

Front Mol Neurosci 2018 1;11:62. Epub 2018 Mar 1.

Department of Pathology and Cell Biology, Columbia University College of Physicians and Surgeons, New York, NY, United States.

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http://dx.doi.org/10.3389/fnmol.2018.00062DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5863619PMC
March 2018

Cdc25A phosphatase: a key cell cycle protein that regulates neuron death in disease and development.

Cell Death Dis 2017 03 23;8(3):e2692. Epub 2017 Mar 23.

Department of Pathology and Cell Biology, Columbia University Medical Center, New York, NY 10032, USA.

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http://dx.doi.org/10.1038/cddis.2017.115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386521PMC
March 2017

Role and regulation of Cdc25A phosphatase in neuron death induced by NGF deprivation or -amyloid.

Cell Death Discov 2016 12;2:16083. Epub 2016 Dec 12.

Cell Biology and Physiology Division, CSIR-Indian Institute of Chemical Biology , 4 Raja S. C. Mullick Road, Kolkata 700 032, India.

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http://dx.doi.org/10.1038/cddiscovery.2016.83DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5149581PMC
December 2016

Activating Transcription Factor 4 (ATF4) modulates Rho GTPase levels and function via regulation of RhoGDIα.

Sci Rep 2016 11 14;6:36952. Epub 2016 Nov 14.

Department of Pathology &Cell Biology and Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Medical Center, New York, NY 10032, USA.

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http://dx.doi.org/10.1038/srep36952DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5107905PMC
November 2016

Activating transcription factor 4 (ATF4) modulates post-synaptic development and dendritic spine morphology.

Front Cell Neurosci 2014 30;8:177. Epub 2014 Jun 30.

Department of Pathology and Cell Biology, Columbia University Medical Center New York, NY, USA.

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http://dx.doi.org/10.3389/fncel.2014.00177DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4075335PMC
July 2014

Caspase-2 is essential for c-Jun transcriptional activation and Bim induction in neuron death.

Biochem J 2013 Oct;455(1):15-25

*Department of Pathology and Cell Biology, Columbia University College of Physicians and Surgeons, New York, NY 10032, U.S.A.

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http://dx.doi.org/10.1042/BJ20130556DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3905453PMC
October 2013

Cell death and the developing enteric nervous system.

Neurochem Int 2012 Nov 8;61(6):839-47. Epub 2012 Feb 8.

Department of Pathology and Cell Biology, Columbia University, New York, NY 10032, USA.

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http://dx.doi.org/10.1016/j.neuint.2012.01.028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3398212PMC
November 2012

Reciprocal actions of ATF5 and Shh in proliferation of cerebellar granule neuron progenitor cells.

Dev Neurobiol 2012 Jun;72(6):789-804

Department of Pathology and Cell Biology, Columbia University College of Physicians and Surgeons, New York, New York, USA.

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http://dx.doi.org/10.1002/dneu.20979DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3857133PMC
June 2012

Akt as a victim, villain and potential hero in Parkinson's disease pathophysiology and treatment.

Cell Mol Neurobiol 2011 Oct 10;31(7):969-78. Epub 2011 Mar 10.

Department of Pathology and Cell Biology, Columbia University College of Physicians and Surgeons, 630W. 168th Street, New York, NY 10032, USA.

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http://dx.doi.org/10.1007/s10571-011-9671-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3678379PMC
October 2011

RTP801/REDD1 regulates the timing of cortical neurogenesis and neuron migration.

J Neurosci 2011 Mar;31(9):3186-96

Department of Pathology and Cell Biology, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA.

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http://dx.doi.org/10.1523/JNEUROSCI.4011-10.2011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3089438PMC
March 2011

Gata2 is required for migration and differentiation of retinorecipient neurons in the superior colliculus.

J Neurosci 2011 Mar;31(12):4444-55

Department of Pharmacology, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA.

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http://dx.doi.org/10.1523/JNEUROSCI.4616-10.2011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3076930PMC
March 2011

Sertad1 plays an essential role in developmental and pathological neuron death.

J Neurosci 2010 Mar;30(11):3973-82

Department of Pathology and Cell Biology and Taub Center for Alzheimer's Disease Research, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA.

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http://dx.doi.org/10.1523/JNEUROSCI.6421-09.2010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2861041PMC
March 2010

Rapamycin protects against neuron death in in vitro and in vivo models of Parkinson's disease.

J Neurosci 2010 Jan;30(3):1166-75

Department of Pathology and Cell Biology, Columbia University, New York, New York 10032, USA.

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http://dx.doi.org/10.1523/JNEUROSCI.3944-09.2010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2880868PMC
January 2010

Cbl negatively regulates JNK activation and cell death.

Cell Res 2009 Aug;19(8):950-61

Department of Biological Sciences, Columbia University, New York, New York, USA.

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http://dx.doi.org/10.1038/cr.2009.74DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2739106PMC
August 2009

Cell death pathways in Parkinson's disease: proximal triggers, distal effectors, and final steps.

Apoptosis 2009 Apr;14(4):478-500

Department of Neurology, Columbia University School of Medicine, New York, NY, USA.

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http://dx.doi.org/10.1007/s10495-008-0309-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2754154PMC
April 2009

The transcription factor ATF5: role in neurodevelopment and neural tumors.

J Neurochem 2009 Jan 15;108(1):11-22. Epub 2008 Nov 15.

Department of Pathology and Cell Biology Columbia University College of Physicians and Surgeons, New York, New York 10032, USA.

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http://dx.doi.org/10.1111/j.1471-4159.2008.05749.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2680418PMC
January 2009

Isolation and culture of post-natal mouse cerebellar granule neuron progenitor cells and neurons.

J Vis Exp 2009 Jan 16(23). Epub 2009 Jan 16.

Department of Genetics and Development, Columbia University, USA.

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http://dx.doi.org/10.3791/990DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2781826PMC
January 2009

Protocol for culturing sympathetic neurons from rat superior cervical ganglia (SCG).

J Vis Exp 2009 Jan 30(23). Epub 2009 Jan 30.

Department of Biology, Columbia University, USA.

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http://www.jove.com/index/Details.stp?ID=988
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http://dx.doi.org/10.3791/988DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2763297PMC
January 2009

RTP801 is induced in Parkinson's disease and mediates neuron death by inhibiting Akt phosphorylation/activation.

J Neurosci 2008 Dec;28(53):14363-71

Department of Pathology and Cell Biology, Columbia University, New York, New York 10032, USA.

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http://dx.doi.org/10.1523/JNEUROSCI.3928-08.2008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3865436PMC
December 2008

Glucagon-like peptide-1 (GLP-1) diminishes neuronal degeneration and death caused by NGF deprivation by suppressing Bim induction.

Neurochem Res 2008 Sep 20;33(9):1845-51. Epub 2008 Mar 20.

Department of Pathology, Center for Neurobiology and Behavior and Taub Center for Alzheimer's Disease Research, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA.

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http://dx.doi.org/10.1007/s11064-008-9646-4DOI Listing
September 2008

Pro-apoptotic Bim induction in response to nerve growth factor deprivation requires simultaneous activation of three different death signaling pathways.

J Biol Chem 2007 Oct 16;282(40):29368-74. Epub 2007 Aug 16.

Department of Pathology, Center for Neurobiology and Behavior, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA.

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http://dx.doi.org/10.1074/jbc.M702634200DOI Listing
October 2007

Identification of POSH2, a novel homologue of the c-Jun N-terminal kinase scaffold protein POSH.

Dev Neurosci 2007 ;29(4-5):355-62

Department of Pediatrics, Columbia University Health Sciences, New York, NY 10032, USA.

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http://search.proquest.com/openview/71fbda559c0e510c1f405655
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http://www.karger.com/doi/10.1159/000105476
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http://dx.doi.org/10.1159/000105476DOI Listing
October 2007

The transcription factor ATF5 is widely expressed in carcinomas, and interference with its function selectively kills neoplastic, but not nontransformed, breast cell lines.

Int J Cancer 2007 May;120(9):1883-90

Department of Pathology, Columbia University College of Physicians and Surgeons, New York, NY, USA.

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http://doi.wiley.com/10.1002/ijc.22469
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http://dx.doi.org/10.1002/ijc.22469DOI Listing
May 2007

Cell cycle molecules define a pathway required for neuron death in development and disease.

Biochim Biophys Acta 2007 Apr 13;1772(4):392-401. Epub 2006 Dec 13.

Department of Pathology and Center for Neurobiology and Behavior, Columbia University College of Physicians and Surgeons, 630 W. 168th Street, New York, NY 10032, USA.

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http://dx.doi.org/10.1016/j.bbadis.2006.12.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1885990PMC
April 2007

Proapoptotic Nix activates the JNK pathway by interacting with POSH and mediates death in a Parkinson disease model.

J Biol Chem 2007 Jan 9;282(2):1288-95. Epub 2006 Nov 9.

Department of Pediatrics, Columbia University Health Sciences, New York, New York 10032, USA.

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http://dx.doi.org/10.1074/jbc.M607038200DOI Listing
January 2007

Bim is elevated in Alzheimer's disease neurons and is required for beta-amyloid-induced neuronal apoptosis.

J Neurosci 2007 Jan;27(4):893-900

Department of Pathology, Center for Neurobiology and Behavior and Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA.

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http://dx.doi.org/10.1523/JNEUROSCI.3524-06.2007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6672914PMC
January 2007

Direct interaction of the molecular scaffolds POSH and JIP is required for apoptotic activation of JNKs.

J Biol Chem 2006 Jun 29;281(22):15517-24. Epub 2006 Mar 29.

Department of Pathology and Center for Neurobiology and Behavior College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA.

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http://dx.doi.org/10.1074/jbc.M601056200DOI Listing
June 2006

Activation of the apoptotic JNK pathway through the Rac1-binding scaffold protein POSH.

Methods Enzymol 2006 ;406:479-89

Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China.

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http://dx.doi.org/10.1016/S0076-6879(06)06036-8DOI Listing
March 2006

Puma and p53 play required roles in death evoked in a cellular model of Parkinson disease.

Neurochem Res 2005 Jun-Jul;30(6-7):839-45

Department of Pathology, Center for Neurobiology and Behavior and Taub Center for Alzheimer's Disease Research, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA.

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http://dx.doi.org/10.1007/s11064-005-6877-5DOI Listing
January 2006

Siah1 interacts with the scaffold protein POSH to promote JNK activation and apoptosis.

J Biol Chem 2006 Jan 17;281(1):303-12. Epub 2005 Oct 17.

Department of Pathology and Center for Neurobiology and Behavior, College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M509060200
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http://dx.doi.org/10.1074/jbc.M509060200DOI Listing
January 2006

Regulation of apoptotic c-Jun N-terminal kinase signaling by a stabilization-based feed-forward loop.

Mol Cell Biol 2005 Nov;25(22):9949-59

Department of Pathology and Center for Neurobiology and Behavior, College of Physicians and Surgeons, Columbia University, 630 W. 168th Street, New York, New York 10032, USA.

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http://dx.doi.org/10.1128/MCB.25.22.9949-9959.2005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1280282PMC
November 2005

You can't go home again: transcriptionally driven alteration of cell signaling by NGF.

Neurochem Res 2005 Oct;30(10):1347-52

Department of Pathology, Center for Neurobiology and Behavior, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA.

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http://dx.doi.org/10.1007/s11064-005-8807-yDOI Listing
October 2005

Bim is a direct target of a neuronal E2F-dependent apoptotic pathway.

J Neurosci 2005 Sep;25(37):8349-58

Department of Pathology, Center for Neurobiology and Behavior, Taub Center for Alzheimer's Disease Research, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA.

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http://dx.doi.org/10.1523/JNEUROSCI.1570-05.2005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6725681PMC
September 2005

ATF5 regulates the proliferation and differentiation of oligodendrocytes.

Mol Cell Neurosci 2005 Jul;29(3):372-80

Farber Institute for Neurosciences, Thomas Jefferson University, Philadelphia, PA 19107, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S104474310500055
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http://dx.doi.org/10.1016/j.mcn.2005.03.004DOI Listing
July 2005

Downregulation of activating transcription factor 5 is required for differentiation of neural progenitor cells into astrocytes.

J Neurosci 2005 Apr;25(15):3889-99

Department of Pathology and Center for Neurobiology and Behavior, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA.

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http://www.jneurosci.org/cgi/doi/10.1523/JNEUROSCI.3447-04.2
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http://dx.doi.org/10.1523/JNEUROSCI.3447-04.2005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6724921PMC
April 2005

Regulation of neuron survival and death by p130 and associated chromatin modifiers.

Genes Dev 2005 Mar;19(6):719-32

Department of Pathology, Columbia University Medical Center, New York, New York 10032, USA.

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http://dx.doi.org/10.1101/gad.1296405DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1065725PMC
March 2005

Analysis of gene expression changes in a cellular model of Parkinson disease.

Neurobiol Dis 2005 Feb;18(1):54-74

Institute of Human Nutrition, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA.

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http://dx.doi.org/10.1016/j.nbd.2004.08.016DOI Listing
February 2005

Highly efficient small interfering RNA delivery to primary mammalian neurons induces MicroRNA-like effects before mRNA degradation.

J Neurosci 2004 Nov;24(45):10040-6

Department of Pathology, Taub Institute for the Study of Alzheimer's Disease and the Aging Brain, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA.

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http://dx.doi.org/10.1523/JNEUROSCI.3643-04.2004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6730191PMC
November 2004

B-myb and C-myb play required roles in neuronal apoptosis evoked by nerve growth factor deprivation and DNA damage.

J Neurosci 2004 Oct;24(40):8720-5

Department of Pathology, Center for Neurobiology and Behavior and Taub Center for Alzheimer's Disease Research, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA.

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http://dx.doi.org/10.1523/JNEUROSCI.1821-04.2004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6729960PMC
October 2004

Regulated expression of ATF5 is required for the progression of neural progenitor cells to neurons.

J Neurosci 2003 Jun;23(11):4590-600

Department of Pathology, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6740805PMC
June 2003

Nerve growth factor selectively regulates expression of transcripts encoding ribosomal proteins.

BMC Neurosci 2002 28;3. Epub 2002 Feb 28.

Department of Pathology and Center for Neurobiology and Behavior, Columbia University College of Physicians and Surgeons, 630 W, 168th Street, New York, NY 10032, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC100322PMC
http://dx.doi.org/10.1186/1471-2202-3-3DOI Listing
April 2003

POSH acts as a scaffold for a multiprotein complex that mediates JNK activation in apoptosis.

EMBO J 2003 Jan;22(2):252-61

Department of Pathology and Center for Neurobiology and Behavior, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA.

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http://emboj.embopress.org/cgi/doi/10.1093/emboj/cdg021
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http://dx.doi.org/10.1093/emboj/cdg021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC140096PMC
January 2003

Nerve growth factor (NGF) down-regulates the Bcl-2 homology 3 (BH3) domain-only protein Bim and suppresses its proapoptotic activity by phosphorylation.

J Biol Chem 2002 Dec 17;277(51):49511-6. Epub 2002 Oct 17.

Department of Pathology and Center for Neurobiology and Behavior, Columbia University College of Physicians and Surgeons, 630 W 168th Street, New York, NY 10032, USA.

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http://dx.doi.org/10.1074/jbc.M208086200DOI Listing
December 2002

Endoplasmic reticulum stress and the unfolded protein response in cellular models of Parkinson's disease.

J Neurosci 2002 Dec;22(24):10690-8

Department of Pathology, Center for Neurobiology and Behavior, Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6758450PMC
December 2002

The basic region and leucine zipper transcription factor MafK is a new nerve growth factor-responsive immediate early gene that regulates neurite outgrowth.

J Neurosci 2002 Oct;22(20):8971-80

Department of Pathology and Center for Neurobiology and Behavior, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6757672PMC
October 2002