Publications by authors named "Lixin Zheng"

89Publications

CD1d1 intrinsic signaling in macrophages controls NLRP3 inflammasome expression during inflammation.

Sci Adv 2020 Oct 21;6(43). Epub 2020 Oct 21.

Institute of Immunology, PLA, Third Military Medical University, Chongqing 400038, People's Republic of China.

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http://dx.doi.org/10.1126/sciadv.aaz7290DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7577718PMC
October 2020

A Benign and Malignant Breast Tumor Classification Method via Efficiently Combining Texture and Morphological Features on Ultrasound Images.

Comput Math Methods Med 2020 1;2020:5894010. Epub 2020 Oct 1.

Quanzhou Institute of Equipment Manufacturing, Haixi Institutes, Chinese Academy of Sciences, 362216 Quanzhou, China.

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http://dx.doi.org/10.1155/2020/5894010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7547332PMC
October 2020

SETDB1 promotes gastric carcinogenesis and metastasis via upregulation of CCND1 and MMP9 expression.

J Pathol 2020 Oct 12. Epub 2020 Oct 12.

Department of Microbiology/Key Laboratory for Experimental Teratology of the Chinese Ministry of Education, School of Basic Medical Science, Cheeloo College of Medicine, Shandong University, Jinan, PR China.

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http://dx.doi.org/10.1002/path.5568DOI Listing
October 2020

Characterization of Resident Corneal Plasmacytoid Dendritic Cells and Their Pivotal Role in Herpes Simplex Keratitis.

Cell Rep 2020 Sep;32(9):108099

Center for Translational Ocular Immunology, Tufts Medical Center, Tufts University School of Medicine, Boston, MA, USA; Department of Ophthalmology, Tufts Medical Center, Tufts University School of Medicine, Boston, MA, USA; Schepens Eye Research Institute, Department of Ophthalmology, Harvard Medical School, Boston, MA, USA; Division of Immunology, Department of Microbiology and Immunobiology, Harvard Medical School, Boston, MA, USA; Program in Immunology, School of Graduate Biomedical Sciences, Tufts University, Boston, MA, USA; Cornea Service, Tufts New England Eye Center, Boston, MA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2020.108099DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7511260PMC
September 2020

High Rumen-Degradable Starch Diet Promotes Hepatic Lipolysis and Disrupts Enterohepatic Circulation of Bile Acids in Dairy Goats.

J Nutr 2020 10;150(10):2755-2763

College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, China.

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http://dx.doi.org/10.1093/jn/nxaa238DOI Listing
October 2020

Metagenomic Analyses of Microbial and Carbohydrate-Active Enzymes in the Rumen of Dairy Goats Fed Different Rumen Degradable Starch.

Front Microbiol 2020 20;11:1003. Epub 2020 May 20.

College of Animal Science and Technology, Northwest A&F University, Yangling, China.

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http://dx.doi.org/10.3389/fmicb.2020.01003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7251062PMC
May 2020

Progress and Prospects on Vaccine Development against SARS-CoV-2.

Vaccines (Basel) 2020 Mar 29;8(2). Epub 2020 Mar 29.

National Engineering Research Center of Immunological Products, Department of Microbiology and Biochemical Pharmacy, College of Pharmacy and Laboratory Medicine, Third Military Medical University, Chongqing, 400038, China.

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http://dx.doi.org/10.3390/vaccines8020153DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7349596PMC
March 2020

Trophic transfer and biotransformation of selenium in the mosquito (Aedes albopictus) and interactive effects with hexavalent chromium.

Environ Pollut 2020 Jul 2;262:114288. Epub 2020 Mar 2.

School of Environmental Science and Engineering, Shanghai Jiao Tong University, 800 Dongchuan Rd, Minhang District, Shanghai 200240, China.

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http://dx.doi.org/10.1016/j.envpol.2020.114288DOI Listing
July 2020

Orphan nuclear receptor Nurr1 promotes Helicobacter pylori-associated gastric carcinogenesis by directly enhancing CDK4 expression.

EBioMedicine 2020 Mar 27;53:102672. Epub 2020 Feb 27.

Department of Microbiology/Key Laboratory for Experimental Teratology of the Chinese Ministry of Education, School of Basic Medical Science, Shandong University, Jinan, Shandong 250012, PR China; Key Laboratory of Infection and Immunity of Shandong Province, School of Basic Medical Science, Shandong University, Jinan, Shandong 250012, PR China; Shandong University-Karolinska Institute Collaborative Laboratory for Cancer Research, Jinan, Shandong 250012, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2020.102672DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7047206PMC
March 2020

Super-resolution reconstruction of knee magnetic resonance imaging based on deep learning.

Comput Methods Programs Biomed 2020 Apr 24;187:105059. Epub 2019 Sep 24.

Engineering Research Centre in Industrial Intellectual Techniques and Systems of Fujian Providence College of Engineering, Huaqiao University, Chenghua North Road, Fengze District, Quanzhou, Fujian 362021, China. Electronic address:

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http://dx.doi.org/10.1016/j.cmpb.2019.105059DOI Listing
April 2020

Identification of AUNIP as a candidate diagnostic and prognostic biomarker for oral squamous cell carcinoma.

EBioMedicine 2019 Sep 10;47:44-57. Epub 2019 Aug 10.

School of Stomatology, Shandong University, Jinan, Shandong 250012, PR China; Shandong Provincial Key Laboratory of Oral Tissue Regeneration, Jinan, Shandong 250012, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2019.08.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6796785PMC
September 2019

Magnesium transporter 1 (MAGT1) deficiency causes selective defects in linked glycosylation and expression of immune-response genes.

J Biol Chem 2019 09 23;294(37):13638-13656. Epub 2019 Jul 23.

Molecular Development of the Immune System Section, Laboratory of Immune System Biology, NIAID, National Institutes of Health, Bethesda, Maryland 20892

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http://dx.doi.org/10.1074/jbc.RA119.008903DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6746436PMC
September 2019

A transfer learning method with deep residual network for pediatric pneumonia diagnosis.

Comput Methods Programs Biomed 2020 Apr 26;187:104964. Epub 2019 Jun 26.

Fujian Provincial Academic Engineering Research Centre in Industrial Intellectual Techniques and Systems, College of Engineering, Huaqiao University, Quanzhou, China. Electronic address:

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http://dx.doi.org/10.1016/j.cmpb.2019.06.023DOI Listing
April 2020

Mg regulation of kinase signaling and immune function.

J Exp Med 2019 08 13;216(8):1828-1842. Epub 2019 Jun 13.

Molecular Development of the Immune System Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD

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http://dx.doi.org/10.1084/jem.20181970DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683994PMC
August 2019

Helicobacter pylori-induced YAP1 nuclear translocation promotes gastric carcinogenesis by enhancing IL-1β expression.

Cancer Med 2019 07 30;8(8):3965-3980. Epub 2019 May 30.

Department of Microbiology/Key Laboratory for Experimental Teratology of Chinese Ministry of Education, School of Medicine, Shandong University, Jinan, P. R. China.

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http://dx.doi.org/10.1002/cam4.2318DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6639191PMC
July 2019

VSIG4 mediates transcriptional inhibition of and β in macrophages.

Sci Adv 2019 01 9;5(1):eaau7426. Epub 2019 Jan 9.

Institute of Immunology, PLA, Third Military Medical University, Chongqing 400038, People's Republic of China.

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http://advances.sciencemag.org/lookup/doi/10.1126/sciadv.aau
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http://dx.doi.org/10.1126/sciadv.aau7426DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326752PMC
January 2019

H. pylori infection induced BMAL1 expression and rhythm disorder aggravate gastric inflammation.

EBioMedicine 2019 Jan 27;39:301-314. Epub 2018 Nov 27.

Department of Microbiology, Key Laboratory for Experimental Teratology of the Chinese Ministry of Education, School of Basic Medical Science, Shandong University, Jinan, Shandong 250012, PR China; Key Laboratory of Infection and Immunity of Shandong Province, School of Basic Medical Science, Shandong University, Jinan, Shandong 250012, PR China; Cancer Research Laboratory, Shandong University, Karolinska Institutet collaborative Laboratory, School of Basic Medical Science, Shandong University, Jinan, Shandong 250012, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2018.11.043DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354571PMC
January 2019

CHAF1A interacts with TCF4 to promote gastric carcinogenesis via upregulation of c-MYC and CCND1 expression.

EBioMedicine 2018 Dec 16;38:69-78. Epub 2018 Nov 16.

Department of Microbiology/Key Laboratory for Experimental Teratology of the Chinese Ministry of Education, School of Basic Medical Science, Shandong University, Jinan, Shandong 250012, PR China; Key Laboratory of Infection and Immunity of Shandong Province, School of Basic Medical Science, Shandong University, Jinan, Shandong 250012, PR China; Shandong University-Karolinska Institutet Collaborative Laboratory for Cancer Research, Jinan, Shandong 250012, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2018.11.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306399PMC
December 2018

Electron-Hole Theory of the Effect of Quantum Nuclei on the X-Ray Absorption Spectra of Liquid Water.

Phys Rev Lett 2018 Sep;121(13):137401

Department of Physics, Temple University, Philadelphia, Pennsylvania 19122, USA.

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https://link.aps.org/doi/10.1103/PhysRevLett.121.137401
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http://dx.doi.org/10.1103/PhysRevLett.121.137401DOI Listing
September 2018

Cytomembrane Infused Polymer Accelerating Delivery of Myelin Antigen Peptide to Treat Experimental Autoimmune Encephalomyelitis.

ACS Nano 2018 11 15;12(11):11579-11590. Epub 2018 Oct 15.

Institute of Immunology, PLA , Third Military Medical University (Army Medical University) , Chongqing 400038 , China.

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http://dx.doi.org/10.1021/acsnano.8b06575DOI Listing
November 2018

Kinetics of corneal leukocytes by intravital multiphoton microscopy.

FASEB J 2019 02 18;33(2):2199-2211. Epub 2018 Sep 18.

Center for Translational Ocular Immunology, Tufts Medical Center, Tufts University School of Medicine, Tufts University, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1096/fj.201800684RRDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338630PMC
February 2019

Hydroxide diffuses slower than hydronium in water because its solvated structure inhibits correlated proton transfer.

Nat Chem 2018 04 12;10(4):413-419. Epub 2018 Mar 12.

Department of Physics, Temple University, Philadelphia, PA, USA.

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http://dx.doi.org/10.1038/s41557-018-0010-2DOI Listing
April 2018

Bioactive polysaccharides and oligosaccharides as possible feed additives to manipulate rumen fermentation in Rusitec fermenters.

Int J Biol Macromol 2018 Apr 16;109:1088-1094. Epub 2017 Nov 16.

College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi 712100, China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01418130173381
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http://dx.doi.org/10.1016/j.ijbiomac.2017.11.098DOI Listing
April 2018

VSIG4 inhibits proinflammatory macrophage activation by reprogramming mitochondrial pyruvate metabolism.

Nat Commun 2017 11 6;8(1):1322. Epub 2017 Nov 6.

Institute of Immunology, PLA, Third Military Medical University, Chongqing, 400038, China.

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http://dx.doi.org/10.1038/s41467-017-01327-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5673889PMC
November 2017

Restimulation-induced cell death: new medical and research perspectives.

Immunol Rev 2017 05;277(1):44-60

Laboratory of Immunology and Clinical Genomics Program, Molecular Development of the Immune System Section, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.

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http://dx.doi.org/10.1111/imr.12535DOI Listing
May 2017

Histone demethylase PHF8 promotes progression and metastasis of gastric cancer.

Am J Cancer Res 2017 1;7(3):448-461. Epub 2017 Mar 1.

Department of Microbiology and Key Laboratory of Infection and Immunity of Shandong Province, School of Basic Medical Science, Shandong University Jinan 250012, Shandong, PR China.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5385635PMC
March 2017

Corneal Reinnervation and Sensation Recovery in Patients With Herpes Zoster Ophthalmicus: An In Vivo and Ex Vivo Study of Corneal Nerves.

Cornea 2016 May;35(5):619-25

*Cornea Service, Massachusetts Eye and Ear Infirmary, Department of Ophthalmology, Harvard Medical School, Boston, MA;†Department of Ophthalmology, Pontificia Universidad Católica de Chile, Santiago, Chile;‡New England Eye Center, Department of Ophthalmology, Tufts Medical Center, Tufts University School of Medicine, Boston, MA;§Eye Center, Somerville Hospital, Department of Surgery, Cambridge Health Alliance, Somerville, MA; and¶Department of Ophthalmology, University of Chicago, Chicago, IL.

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http://dx.doi.org/10.1097/ICO.0000000000000797DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4816653PMC
May 2016

Mitochondrial Protein PGAM5 Regulates Mitophagic Protection against Cell Necroptosis.

PLoS One 2016 25;11(1):e0147792. Epub 2016 Jan 25.

Molecular Development of the Immune System Section, Laboratory of Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America.

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https://pdfs.semanticscholar.org/54bb/29bbfb929cf7efa7bf949a
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http://dx.plos.org/10.1371/journal.pone.0147792
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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0147792PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4725845PMC
July 2016

AUTOIMMUNE DISEASE. Patients with LRBA deficiency show CTLA4 loss and immune dysregulation responsive to abatacept therapy.

Science 2015 Jul;349(6246):436-40

Division of Bone Marrow Transplantation and Immune Deficiency, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, University of Cincinnati, Cincinnati, OH, USA. Division of Immunobiology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center/ University of Cincinnati, Cincinnati, OH, USA.

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http://dx.doi.org/10.1126/science.aaa1663DOI Listing
July 2015

[Effects of basic orange II on proliferation and differentiation of limb bud cells in rat embryos].

Wei Sheng Yan Jiu 2015 Jan;44(1):15-7, 22

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January 2015

Dual proteolytic pathways govern glycolysis and immune competence.

Cell 2014 Dec;159(7):1578-90

Laboratory of Host Defenses, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA; NIAID Clinical Genomics Program, National Institutes of Health, Bethesda, MD 20892, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2014.12.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4297473PMC
December 2014

Genetic deficiency of the mitochondrial protein PGAM5 causes a Parkinson's-like movement disorder.

Nat Commun 2014 Sep 15;5:4930. Epub 2014 Sep 15.

Molecular Development of the Immune System Section, Laboratory of Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1038/ncomms5930DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4457367PMC
September 2014

In vivo effect of mutant ELOVL4 on the expression and function of wild-type ELOVL4.

Invest Ophthalmol Vis Sci 2014 Apr 25;55(4):2705-13. Epub 2014 Apr 25.

Department of Ophthalmology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States.

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http://dx.doi.org/10.1167/iovs.13-13198DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4001787PMC
April 2014

Quantitating lymphocyte programmed cell death in vitro using simple kill assays.

Authors:
Lixin Zheng

Methods Mol Biol 2013 ;979:1-14

Laboratory of Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.

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http://dx.doi.org/10.1007/978-1-62703-290-2_1DOI Listing
August 2013

Congenital B cell lymphocytosis explained by novel germline CARD11 mutations.

J Exp Med 2012 Nov 5;209(12):2247-61. Epub 2012 Nov 5.

Lymphocyte Molecular Genetics Unit, Laboratory of Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health (NIH), Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1084/jem.20120831DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3501355PMC
November 2012

Unilateral herpes zoster ophthalmicus results in bilateral corneal nerve alteration: an in vivo confocal microscopy study.

Ophthalmology 2013 Jan 19;120(1):40-7. Epub 2012 Sep 19.

Ocular Surface Imaging Center and Cornea & Refractive Surgery Service, Massachusetts Eye & Ear Infirmary, Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts 02114, USA.

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http://dx.doi.org/10.1016/j.ophtha.2012.07.036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575640PMC
January 2013

The role of IL-15 in activating STAT5 and fine-tuning IL-17A production in CD4 T lymphocytes.

J Immunol 2012 Nov 19;189(9):4237-46. Epub 2012 Sep 19.

Laboratory of Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.4049/jimmunol.1201476DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3647038PMC
November 2012

Presence of RPE-produced VEGF in a timely manner is critical to choroidal vascular development.

Adv Exp Med Biol 2012 ;723:299-304

Department of Medicine Endocrinology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.

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http://dx.doi.org/10.1007/978-1-4614-0631-0_39DOI Listing
April 2012

Inflammation and the nervous system: the connection in the cornea in patients with infectious keratitis.

Invest Ophthalmol Vis Sci 2011 Jul 11;52(8):5136-43. Epub 2011 Jul 11.

Ocular Surface Imaging Center, Massachusetts Eye & Ear Infirmary, Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts 02114, USA.

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http://iovs.arvojournals.org/article.aspx?doi=10.1167/iovs.1
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http://dx.doi.org/10.1167/iovs.10-7048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3176064PMC
July 2011

The molecular mechanisms of regulatory T cell immunosuppression.

Front Immunol 2011 24;2:60. Epub 2011 Nov 24.

Laboratory of Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health Bethesda, MD, USA.

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http://journal.frontiersin.org/article/10.3389/fimmu.2011.00
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http://dx.doi.org/10.3389/fimmu.2011.00060DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3342245PMC
August 2012

Corneal sensation and subbasal nerve alterations in patients with herpes simplex keratitis: an in vivo confocal microscopy study.

Ophthalmology 2010 Oct 1;117(10):1930-6. Epub 2010 Sep 1.

Massachusetts Eye & Ear Infirmary, Cornea Service & Ocular Surface Imaging Center, Department of Ophthalmology, Harvard Medical School, Boston, Massachusett 02114, USA.

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http://dx.doi.org/10.1016/j.ophtha.2010.07.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2949523PMC
October 2010

The power and the promise of restimulation-induced cell death in human immune diseases.

Immunol Rev 2010 Jul;236:68-82

Laboratory of Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1111/j.1600-065X.2010.00917.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2907538PMC
July 2010

Termination of autophagy and reformation of lysosomes regulated by mTOR.

Nature 2010 Jun 6;465(7300):942-6. Epub 2010 Jun 6.

Laboratory of Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1038/nature09076DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2920749PMC
June 2010

ALPS-ten lessons from an international workshop on a genetic disease of apoptosis.

Immunity 2010 Mar;32(3):291-5

Molecular Development Section, Laboratory of Immunology, NIAID, National Institutes of Health, Bethesda, MD 20892, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S107476131000096
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http://dx.doi.org/10.1016/j.immuni.2010.03.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2858867PMC
March 2010

Unexpected transcriptional activity of the human VMD2 promoter in retinal development.

Adv Exp Med Biol 2010 ;664:211-6

Department of Medicine, University of Oklahoma Health Sciences Center, Oklahoma, OK 73104, USA.

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http://dx.doi.org/10.1007/978-1-4419-1399-9_24DOI Listing
September 2011

Temporal requirement of RPE-derived VEGF in the development of choroidal vasculature.

J Neurochem 2010 Mar 8;112(6):1584-92. Epub 2010 Jan 8.

Department of Medicine Endocrinology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma 73104, USA.

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http://dx.doi.org/10.1111/j.1471-4159.2010.06573.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2933813PMC
March 2010

Curcumin protects retinal cells from light-and oxidant stress-induced cell death.

Free Radic Biol Med 2009 Mar 24;46(5):672-9. Epub 2008 Dec 24.

Department of Ophthalmology, University of Oklahoma Health Sciences Center, Oklahoma City, 73104, USA.

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http://dx.doi.org/10.1016/j.freeradbiomed.2008.12.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2810836PMC
March 2009

Casein kinase 1alpha governs antigen-receptor-induced NF-kappaB activation and human lymphoma cell survival.

Nature 2009 Mar 31;458(7234):92-6. Epub 2008 Dec 31.

Molecular Development Section, Laboratory of Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1038/nature07613DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688735PMC
March 2009

Interferon-inducible immunity-related GTPase Irgm1 regulates IFN gamma-dependent host defense, lymphocyte survival and autophagy.

Autophagy 2009 Feb 19;5(2):232-4. Epub 2009 Feb 19.

Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892-8003, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2749220PMC
http://dx.doi.org/10.4161/auto.5.2.7445DOI Listing
February 2009

The immunity-related GTPase Irgm1 promotes the expansion of activated CD4+ T cell populations by preventing interferon-gamma-induced cell death.

Nat Immunol 2008 Nov 21;9(11):1279-87. Epub 2008 Sep 21.

Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1038/ni.1653DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2580721PMC
November 2008

Critical role for BIM in T cell receptor restimulation-induced death.

Biol Direct 2008 Aug 20;3:34. Epub 2008 Aug 20.

Department of Laboratory Medicine, Clinical Center, National Institutes of Health, Bethesda, MD 20892-1508, USA.

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http://dx.doi.org/10.1186/1745-6150-3-34DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2529272PMC
August 2008

Role of BCL-XL in photoreceptor survival.

Adv Exp Med Biol 2008 ;613:69-74

Department of Medicine, Dean A. McGee Eye Institute, Oklahoma City, OK, USA.

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http://dx.doi.org/10.1007/978-0-387-74904-4_7DOI Listing
February 2008

CD4+CD25+Foxp3+ regulatory T cells induce cytokine deprivation-mediated apoptosis of effector CD4+ T cells.

Nat Immunol 2007 Dec 4;8(12):1353-62. Epub 2007 Nov 4.

Laboratory of Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA.

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http://www.nature.com/articles/ni1536
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http://dx.doi.org/10.1038/ni1536DOI Listing
December 2007

NRAS mutation causes a human autoimmune lymphoproliferative syndrome.

Proc Natl Acad Sci U S A 2007 May 16;104(21):8953-8. Epub 2007 May 16.

Department of Laboratory Medicine, Clinical Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1073/pnas.0702975104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1885609PMC
May 2007

Loss of BCL-XL in rod photoreceptors: Increased susceptibility to bright light stress.

Invest Ophthalmol Vis Sci 2006 Dec;47(12):5583-9

Department of Ophthalmology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA.

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http://dx.doi.org/10.1167/iovs.06-0163DOI Listing
December 2006

T helper 2 cells' preferred way to die.

Immunity 2006 Aug;25(2):187-8

Laboratory of Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1016/j.immuni.2006.08.006DOI Listing
August 2006

Caspase-8 regulation by direct interaction with TRAF6 in T cell receptor-induced NF-kappaB activation.

Curr Biol 2006 Aug;16(16):1666-71

Molecular Development Section, Laboratory of Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1016/j.cub.2006.06.062DOI Listing
August 2006

Mouse opsin promoter-directed Cre recombinase expression in transgenic mice.

Mol Vis 2006 Apr 18;12:389-98. Epub 2006 Apr 18.

Department of Cell Biology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.

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April 2006

Competitive control of independent programs of tumor necrosis factor receptor-induced cell death by TRADD and RIP1.

Mol Cell Biol 2006 May;26(9):3505-13

Laboratory of Immunology, National Institute of Allergy and Infectious Diseases, NIH, 9000 Rockville Pike, 10/11D09, Bethesda, MD 20892, USA.

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http://mcb.asm.org/cgi/doi/10.1128/MCB.26.9.3505-3513.2006
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http://dx.doi.org/10.1128/MCB.26.9.3505-3513.2006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1447428PMC
May 2006

Genetic alterations in caspase-10 may be causative or protective in autoimmune lymphoproliferative syndrome.

Hum Genet 2006 Apr 31;119(3):284-94. Epub 2006 Jan 31.

Genetics and Molecular Biology Branch, National Human Genome Research Institute, NIH, DHHS, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1007/s00439-006-0138-9DOI Listing
April 2006

Crystal structure of MC159 reveals molecular mechanism of DISC assembly and FLIP inhibition.

Mol Cell 2005 Dec;20(6):939-49

Department of Biochemistry, Weill Medical College of Cornell University, New York, New York 10021, USA.

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http://dx.doi.org/10.1016/j.molcel.2005.10.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2908330PMC
December 2005

Amelioration of inflammatory arthritis by targeting the pre-ligand assembly domain of tumor necrosis factor receptors.

Nat Med 2005 Oct 18;11(10):1066-72. Epub 2005 Sep 18.

Laboratory of Immunology, Building 10, Room 11N311, 10 Center Drive, MSC 1892, National Institute of Allergy and Infectious Disease, National Institutes of Health, Bethesda, Maryland 20892, USA.

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http://www.nature.com/articles/nm1304
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October 2005

Requirement for caspase-8 in NF-kappaB activation by antigen receptor.

Science 2005 Mar;307(5714):1465-8

Laboratory of Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1126/science.1104765DOI Listing
March 2005

Induction of apoptosis and activation of NF-kappaB by CD95 require different signalling thresholds.

EMBO Rep 2004 Nov;5(11):1084-9

The Ben May Institute for Cancer Research, University of Chicago, 924 E 57th Street, Chicago, Illinois 60637, USA.

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http://dx.doi.org/10.1038/sj.embor.7400280DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1299175PMC
November 2004

A role for tumor necrosis factor receptor-2 and receptor-interacting protein in programmed necrosis and antiviral responses.

J Biol Chem 2003 Dec 7;278(51):51613-21. Epub 2003 Oct 7.

Laboratory of Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M305633200
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December 2003

The death effector domain protein family: regulators of cellular homeostasis.

Nat Immunol 2003 May;4(5):404-9

Laboratory of Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1038/ni0503-404DOI Listing
May 2003

Pleiotropic defects in lymphocyte activation caused by caspase-8 mutations lead to human immunodeficiency.

Nature 2002 Sep;419(6905):395-9

Laboratory of Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1038/nature01063DOI Listing
September 2002