Lixin Lang

Lixin Lang

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Lixin Lang

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Ga-NOTA-Aca-BBN(7-14) PET imaging of GRPR in children with optic pathway glioma.

Eur J Nucl Med Mol Imaging 2019 Sep 3;46(10):2152-2162. Epub 2019 Jul 3.

Laboratory of Molecular Imaging and Nanomedicine (LOMIN), National Institute of Biomedical Imaging and Bioengineering (NIBIB), National Institutes of Health (NIH), Bethesda, MD, 20892, USA.

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http://dx.doi.org/10.1007/s00259-019-04392-7DOI Listing
September 2019

Antidiabetic Effect of Abextide, a Long-Acting Exendin-4 Analogue in Cynomolgus Monkeys.

Adv Healthc Mater 2019 Jun 9;8(12):e1800686. Epub 2018 Oct 9.

Laboratory of Molecular Imaging and Nanomedicine, National Institute of Biomedical Imaging and Bioengineering (NIBIB), National Institutes of Health (NIH), 9000 Rockville Pike, Bethesda, MD, 20892, USA.

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http://doi.wiley.com/10.1002/adhm.201800686
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http://dx.doi.org/10.1002/adhm.201800686DOI Listing
June 2019

An Albumin Sandwich Enhances in Vivo Circulation and Stability of Metabolically Labile Peptides.

Bioconjug Chem 2019 Jun 6;30(6):1711-1723. Epub 2019 Jun 6.

State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics & Center for Molecular Imaging and Translational Medicine, School of Public Health , Xiamen University , Xiamen 361102 , China.

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http://dx.doi.org/10.1021/acs.bioconjchem.9b00258DOI Listing
June 2019

An Albumin-Binding T- T Dual-Modal MRI Contrast Agents for Improved Sensitivity and Accuracy in Tumor Imaging.

Bioconjug Chem 2019 Jun 31;30(6):1821-1829. Epub 2019 May 31.

Laboratory of Molecular Imaging and Nanomedicine, National Institute of Biomedical Imaging and Bioengineering , National Institutes of Health , Bethesda , Maryland 20892 , United States.

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http://dx.doi.org/10.1021/acs.bioconjchem.9b00349DOI Listing
June 2019

Improving the Theranostic Potential of Exendin 4 by Reducing the Renal Radioactivity through Brush Border Membrane Enzyme-Mediated Degradation.

Bioconjug Chem 2019 Jun 5;30(6):1745-1753. Epub 2019 Jun 5.

Laboratory of Molecular Imaging and Nanomedicine , National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health , Bethesda , Maryland 20892 , United States.

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http://dx.doi.org/10.1021/acs.bioconjchem.9b00280DOI Listing
June 2019

First-in-human study of PET and optical dual-modality image-guided surgery in glioblastoma using Ga-IRDye800CW-BBN.

Theranostics 2018 3;8(9):2508-2520. Epub 2018 Apr 3.

Laboratory of Molecular Imaging and Nanomedicine (LOMIN), National Institute of Biomedical Imaging and Bioengineering (NIBIB), National Institutes of Health (NIH), Bethesda, Maryland, United States.

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http://dx.doi.org/10.7150/thno.25599DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5928906PMC
April 2019

A Logic-Gated Modular Nanovesicle Enables Programmable Drug Release for On-Demand Chemotherapy.

Theranostics 2019 14;9(5):1358-1368. Epub 2019 Feb 14.

Laboratory of Molecular Imaging and Nanomedicine, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.7150/thno.32106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6401502PMC
February 2019

Ga-BBN-RGD PET/CT for GRPR and Integrin αβ Imaging in Patients with Breast Cancer.

Theranostics 2018 1;8(4):1121-1130. Epub 2018 Jan 1.

Laboratory of Molecular Imaging and Nanomedicine (LOMIN), National Institute of Biomedical Imaging and Bioengineering (NIBIB), National Institutes of Health (NIH), Bethesda, Maryland, 20892, USA.

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http://dx.doi.org/10.7150/thno.22601DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5817114PMC
January 2019

68Ga-NOTA-RM26 PET/CT in the Evaluation of Breast Cancer: A Pilot Prospective Study.

Clin Nucl Med 2018 Sep;43(9):663-669

Laboratory of Molecular Imaging and Nanomedicine, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, MD.

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http://dx.doi.org/10.1097/RLU.0000000000002209DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6076351PMC
September 2018

Combined 68Ga-NOTA-PRGD2 and 18F-FDG PET/CT Can Discriminate Uncommon Meningioma Mimicking High-Grade Glioma.

Clin Nucl Med 2018 Sep;43(9):648-654

Laboratory of Molecular Imaging and Nanomedicine, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, MD.

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http://dx.doi.org/10.1097/RLU.0000000000002233DOI Listing
September 2018

Single Low-Dose Injection of Evans Blue Modified PSMA-617 Radioligand Therapy Eliminates Prostate-Specific Membrane Antigen Positive Tumors.

Bioconjug Chem 2018 09 22;29(9):3213-3221. Epub 2018 Aug 22.

Laboratory of Molecular Imaging and Nanomedicine, National Institute of Biomedical Imaging and Bioengineering , National Institutes of Health , Bethesda , Maryland , United States.

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http://dx.doi.org/10.1021/acs.bioconjchem.8b00556DOI Listing
September 2018

PET Using a GRPR Antagonist Ga-RM26 in Healthy Volunteers and Prostate Cancer Patients.

J Nucl Med 2018 06 9;59(6):922-928. Epub 2017 Nov 9.

Laboratory of Molecular Imaging and Nanomedicine (LOMIN), National Institute of Biomedical Imaging and Bioengineering (NIBIB), National Institutes of Health (NIH), Bethesda, Maryland

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http://dx.doi.org/10.2967/jnumed.117.198929DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6004560PMC
June 2018

Predictive probability methods for interim monitoring in clinical trials with longitudinal outcomes.

Stat Med 2018 06 17;37(14):2187-2207. Epub 2018 Apr 17.

Global Biometric Sciences, Bristol-Myers Squibb, New Jersey, United States.

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http://dx.doi.org/10.1002/sim.7685DOI Listing
June 2018

Quantification of Tumor Vascular Permeability and Blood Volume by Positron Emission Tomography.

Theranostics 2017 14;7(9):2363-2376. Epub 2017 Jun 14.

Laboratory of Molecular Imaging and Nanomedicine, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, Maryland.

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http://dx.doi.org/10.7150/thno.19898DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5525742PMC
March 2018

Positron Emission Tomography Imaging of Prostate Cancer with Ga-68-Labeled Gastrin-Releasing Peptide Receptor Agonist BBN and Antagonist RM26.

Bioconjug Chem 2018 02 9;29(2):410-419. Epub 2018 Jan 9.

Laboratory of Molecular Imaging and Nanomedicine, National Institute of Biomedical Imaging and Bioengineering (NIBIB), National Institutes of Health (NIH) , Bethesda, Maryland 20892, United States.

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http://pubs.acs.org/doi/10.1021/acs.bioconjchem.7b00726
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http://dx.doi.org/10.1021/acs.bioconjchem.7b00726DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824342PMC
February 2018

Microsurgery guided by sequential preoperative lymphography using Ga-NEB PET and MRI in patients with lower-limb lymphedema.

Eur J Nucl Med Mol Imaging 2017 Aug 5;44(9):1501-1510. Epub 2017 Apr 5.

Laboratory of Molecular Imaging and Nanomedicine (LOMIN), National Institute of Biomedical Imaging and Bioengineering (NIBIB), National Institutes of Health (NIH), Bethesda, MD, 20892, USA.

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http://dx.doi.org/10.1007/s00259-017-3676-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5507721PMC
August 2017

Clinical Translation of a Dual Integrin αvβ3- and Gastrin-Releasing Peptide Receptor-Targeting PET Radiotracer, 68Ga-BBN-RGD.

J Nucl Med 2017 02 4;58(2):228-234. Epub 2016 Aug 4.

Laboratory of Molecular Imaging and Nanomedicine (LOMIN), National Institute of Biomedical Imaging and Bioengineering (NIBIB), National Institutes of Health (NIH), Bethesda, Maryland

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http://dx.doi.org/10.2967/jnumed.116.177048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288740PMC
February 2017

Chemical Conjugation of Evans Blue Derivative: A Strategy to Develop Long-Acting Therapeutics through Albumin Binding.

Theranostics 2016 1;6(2):243-53. Epub 2016 Jan 1.

2. Laboratory of Molecular Imaging and Nanomedicine, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, Maryland, USA.

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http://dx.doi.org/10.7150/thno.14322DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4729772PMC
January 2017

A photothermally responsive nanoprobe for bioimaging based on Edman degradation.

Nanoscale 2016 May;8(20):10553-7

Laboratory of Molecular Imaging and Nanomedicine (LOMIN), National Institute of Biomedical Imaging and Bioengineering (NIBIB), National Institutes of Health (NIH), Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1039/c6nr01400cDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5223088PMC
May 2016

68Ga-NOTA-Aca-BBN(7-14) PET/CT in Healthy Volunteers and Glioma Patients.

J Nucl Med 2016 Jan 8;57(1):9-14. Epub 2015 Oct 8.

Laboratory of Molecular Imaging and Nanomedicine, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, Maryland; and

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http://dx.doi.org/10.2967/jnumed.115.165316DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5242342PMC
January 2016

Stable Evans Blue Derived Exendin-4 Peptide for Type 2 Diabetes Treatment.

Bioconjug Chem 2016 Jan 10;27(1):54-8. Epub 2015 Dec 10.

Laboratory of Molecular Imaging and Nanomedicine (LOMIN), National Institute of Biomedical Imaging and Bioengineer-ing (NIBIB), National Institutes of Health (NIH) , Bethesda, Maryland 20892, United States.

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http://pubs.acs.org/doi/10.1021/acs.bioconjchem.5b00625
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http://dx.doi.org/10.1021/acs.bioconjchem.5b00625DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5219937PMC
January 2016

Quantitative Evaluation of Tumor Early Response to a Vascular-Disrupting Agent with Dynamic PET.

Mol Imaging Biol 2015 Dec;17(6):865-73

Laboratory of Molecular Imaging and Nanomedicine, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, 35A Convent Dr, GD937, Bethesda, MD, 20892-3759, USA.

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http://dx.doi.org/10.1007/s11307-015-0854-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5218587PMC
December 2015

(18)F-Alfatide II PET/CT in healthy human volunteers and patients with brain metastases.

Eur J Nucl Med Mol Imaging 2015 Dec 1;42(13):2021-8. Epub 2015 Jul 1.

Laboratory of Molecular Imaging and Nanomedicine, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, MD, USA.

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http://link.springer.com/10.1007/s00259-015-3118-2
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http://dx.doi.org/10.1007/s00259-015-3118-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4626365PMC
December 2015

68Ga-NOTA-PRGD2 PET/CT for Integrin Imaging in Patients with Lung Cancer.

J Nucl Med 2015 Dec 1;56(12):1823-7. Epub 2015 Oct 1.

Laboratory of Molecular Imaging and Nanomedicine (LOMIN), National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, Maryland; and

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http://dx.doi.org/10.2967/jnumed.115.160648DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5223097PMC
December 2015

Clinical Translation of an Albumin-Binding PET Radiotracer 68Ga-NEB.

J Nucl Med 2015 Oct 6;56(10):1609-14. Epub 2015 Aug 6.

Laboratory of Molecular Imaging and Nanomedicine, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, Maryland

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http://dx.doi.org/10.2967/jnumed.115.159640DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5238512PMC
October 2015

In vivo albumin labeling and lymphatic imaging.

Proc Natl Acad Sci U S A 2015 Jan 22;112(1):208-13. Epub 2014 Dec 22.

Laboratory of Molecular Imaging and Nanomedicine, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, MD 20892

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http://dx.doi.org/10.1073/pnas.1414821112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4291643PMC
January 2015

Stability analysis of glutamic acid linked peptides coupled to NOTA through different chemical linkages.

Mol Pharm 2014 Nov 24;11(11):3867-74. Epub 2014 Feb 24.

Laboratory of Molecular Imaging and Nanomedicine (LOMIN), National Institute of Biomedical Imaging and Bioengineering (NIBIB), National Institutes of Health (NIH) , 31 Center Drive, Building 31, 1C22, Bethesda, Maryland 20892-2281, United States.

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http://dx.doi.org/10.1021/mp400706qDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4224566PMC
November 2014

Longitudinal PET imaging of muscular inflammation using 18F-DPA-714 and 18F-Alfatide II and differentiation with tumors.

Theranostics 2014 26;4(5):546-55. Epub 2014 Feb 26.

2. Laboratory of Molecular Imaging and Nanomedicine, National Institute of Biomedical Imaging and Bioengineering (NIBIB), National Institutes of Health (NIH), Bethesda, USA.

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http://dx.doi.org/10.7150/thno.8159DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3966057PMC
November 2014

In Vivo Labeling of Serum Albumin for PET.

J Nucl Med 2014 Jul 19;55(7):1150-6. Epub 2014 May 19.

Laboratory of Molecular Imaging and Nanomedicine (LOMIN), National Institute of Biomedical Imaging and Bioengineering (NIBIB), National Institutes of Health (NIH), Bethesda, Maryland

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http://dx.doi.org/10.2967/jnumed.114.139642DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4576845PMC
July 2014

Comparison of three dimeric 18F-AlF-NOTA-RGD tracers.

Mol Imaging Biol 2014 Apr;16(2):274-83

Department of Biomedical Engineering, and Wuhan National Laboratory for Optoelectronics(WNLO), Huazhong University of Science and Technology, Wuhan, 430074, China.

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http://dx.doi.org/10.1007/s11307-013-0668-1DOI Listing
April 2014

Rational design of matrix metalloproteinase-13 activatable probes for enhanced specificity.

ACS Chem Biol 2014 Feb 3;9(2):510-6. Epub 2013 Dec 3.

Center for Molecular Imaging and Translational Medicine (CMITM), School of Public Health, Xiamen University , Xiamen 361005, China.

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http://dx.doi.org/10.1021/cb400698sDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944097PMC
February 2014

(18)F-alfatide II and (18)F-FDG dual-tracer dynamic PET for parametric, early prediction of tumor response to therapy.

J Nucl Med 2014 Jan 14;55(1):154-60. Epub 2013 Nov 14.

Department of Biomedical Engineering and Wuhan National Laboratory for Optoelectronics (WNLO), Huazhong University of Science and Technology, Wuhan, Hubei, China.

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http://dx.doi.org/10.2967/jnumed.113.122069DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4209961PMC
January 2014

Development of a new thiol site-specific prosthetic group and its conjugation with [Cys(40)]-exendin-4 for in vivo targeting of insulinomas.

Bioconjug Chem 2013 Jul 28;24(7):1191-200. Epub 2013 Jun 28.

National Institute of Biomedical Imaging and Bioengineering (NIBIB), National Institutes of Health (NIH), 31 Center Drive, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1021/bc400084uDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3779517PMC
July 2013

First experience of 18F-alfatide in lung cancer patients using a new lyophilized kit for rapid radiofluorination.

J Nucl Med 2013 May 3;54(5):691-8. Epub 2013 Apr 3.

Key Laboratory of Nuclear Medicine, Ministry of Health, Jiangsu Key Laboratory of Molecular Nuclear Medicine, Jiangsu Institute of Nuclear Medicine, Wuxi, China.

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http://dx.doi.org/10.2967/jnumed.112.113563DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3683452PMC
May 2013

One-step and one-pot-two-step radiosynthesis of cyclo-RGD-(18)F-aryltrifluoroborate conjugates for functional imaging.

Am J Nucl Med Mol Imaging 2013 5;3(1):44-56. Epub 2013 Jan 5.

Department of Chemistry, University of British Columbia 2036 Main Mall, Vancouver, B.C., V6T-1Z1, Canada.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3545361PMC
January 2013

Longitudinal PET imaging of doxorubicin-induced cell death with 18F-Annexin V.

Mol Imaging Biol 2012 Dec;14(6):762-70

Department of Nuclear Medicine, Xiangya Hospital, Central South University, Changsha, 410008, China.

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http://dx.doi.org/10.1007/s11307-012-0551-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3387344PMC
December 2012

Quantitative analysis and parametric imaging of 18F-labeled monomeric and dimeric RGD peptides using compartment model.

Mol Imaging Biol 2012 Dec;14(6):743-52

Department of Biomedical Engineering, Huazhong University of Science and Technology, 505 Bldg. D11, 1037 Luoyu Rd., Wuhan, Hubei, China 430074.

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http://dx.doi.org/10.1007/s11307-012-0541-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3401513PMC
December 2012

PET of glucagonlike peptide receptor upregulation after myocardial ischemia or reperfusion injury.

J Nucl Med 2012 Dec 8;53(12):1960-8. Epub 2012 Nov 8.

Department of Cardiology, Xijing Hospital, Fourth Military Medical University, Xi'an, China.

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http://dx.doi.org/10.2967/jnumed.112.109413DOI Listing
December 2012

Evaluation of fluorine-labeled gastrin-releasing peptide receptor (GRPR) agonists and antagonists by LC/MS.

Amino Acids 2012 Oct 22;43(4):1625-32. Epub 2012 Feb 22.

Laboratory of Molecular Imaging and Nanomedicine (LOMIN), National Institute of Biomedical Imaging and Bioengineering (NIBIB), National Institutes of Health (NIH), 31 Center Dr, Suite 1C14, Bethesda, MD 20892-2281, USA.

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http://dx.doi.org/10.1007/s00726-012-1238-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3387330PMC
October 2012

N-Succinimidyl 4-[(18)F]-fluoromethylbenzoate-labeled dimeric RGD peptide for imaging tumor integrin expression.

Amino Acids 2012 Sep 31;43(3):1349-57. Epub 2011 Dec 31.

Department of Medical Imaging and Nuclear Medicine, Fourth Affiliated Hospital, Harbin Medical University, Harbin, China.

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http://link.springer.com/10.1007/s00726-011-1208-4
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http://dx.doi.org/10.1007/s00726-011-1208-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3577934PMC
September 2012

Quantitative analysis and comparison study of [18F]AlF-NOTA-PRGD2, [18F]FPPRGD2 and [68Ga]Ga-NOTA-PRGD2 using a reference tissue model.

PLoS One 2012 18;7(5):e37506. Epub 2012 May 18.

Laboratory of Molecular Imaging and Nanomedicine, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, Maryland, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0037506PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3356326PMC
September 2012

Long-term multimodal imaging of tumor draining sentinel lymph nodes using mesoporous silica-based nanoprobes.

Biomaterials 2012 Jun 16;33(17):4370-8. Epub 2012 Mar 16.

Laboratory of Molecular Imaging and Nanomedicine, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1016/j.biomaterials.2012.02.060DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3758914PMC
June 2012

PET imaging of angiogenesis after myocardial infarction/reperfusion using a one-step labeled integrin-targeted tracer 18F-AlF-NOTA-PRGD2.

Eur J Nucl Med Mol Imaging 2012 Apr 25;39(4):683-92. Epub 2012 Jan 25.

Department of Cardiology, Xijing Hospital, The Fourth Military Medical University, Xi'an, China.

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http://dx.doi.org/10.1007/s00259-011-2052-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3319105PMC
April 2012

PET imaging of EGF receptors using [18F]FBEM-EGF in a head and neck squamous cell carcinoma model.

Eur J Nucl Med Mol Imaging 2012 Feb 23;39(2):300-8. Epub 2011 Nov 23.

Department of Medical Imaging and Nuclear Medicine, Fourth Affiliated Hospital, Harbin Medical University, 37 Yinhang Street, Nangang District, Harbin 150001, China.

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http://dx.doi.org/10.1007/s00259-011-1969-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3262064PMC
February 2012

Comparison study of [18F]FAl-NOTA-PRGD2, [18F]FPPRGD2, and [68Ga]Ga-NOTA-PRGD2 for PET imaging of U87MG tumors in mice.

Bioconjug Chem 2011 Dec 3;22(12):2415-22. Epub 2011 Nov 3.

Laboratory of Molecular Imaging and Nanomedicine (LOMIN), Radiology and Imaging Sciences, Clinical Center, National Institute of Biomedical Imaging and Bioengineering (NIBIB), National Institutes of Health (NIH ), Bethesda, Maryland 20892, United States.

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http://dx.doi.org/10.1021/bc200197hDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3244506PMC
December 2011

New Methods for Labeling RGD Peptides with Bromine-76.

Theranostics 2011 22;1:341-53. Epub 2011 Aug 22.

1. Laboratory of Molecular Imaging and Nanomedicine (LOMIN), National Institute of Biomedical Imaging and Bioengineering (NIBIB), National Institutes of Health (NIH), Bethesda, Maryland, 20892, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3177243PMC
November 2011

Striatal adenosine A(2A) receptor-mediated positron emission tomographic imaging in 6-hydroxydopamine-lesioned rats using [(18)F]-MRS5425.

Nucl Med Biol 2011 Aug 30;38(6):897-906. Epub 2011 Mar 30.

Laboratory of Molecular Imaging and Nanomedicine, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1016/j.nucmedbio.2011.01.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3157043PMC
August 2011

PET imaging of early response to the tyrosine kinase inhibitor ZD4190.

Eur J Nucl Med Mol Imaging 2011 Jul 1;38(7):1237-47. Epub 2011 Mar 1.

Key Laboratory of Nuclear Medicine, Ministry of Health, Jiangsu Key Laboratory of Molecular Nuclear Medicine, Jiangsu Institute of Nuclear Medicine, Wuxi, Jiangsu, China.

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http://dx.doi.org/10.1007/s00259-011-1742-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3184245PMC
July 2011

F-Labeled GRPR Agonists and Antagonists: A Comparative Study in Prostate Cancer Imaging.

Theranostics 2011 ;1:220-9

Key Laboratory of Nuclear Medicine, Ministry of Health, Jiangsu Key Laboratory of Molecular Nuclear Medicine, Jiangsu Institute of Nuclear Medicine, Wuxi, Jiangsu, 214063, China.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3086613PMC
July 2011

LC/MS evaluation of metabolism and membrane transport of bombesin peptides.

Amino Acids 2011 Feb 30;40(2):669-75. Epub 2010 Jul 30.

Laboratory of Molecular Imaging and Nanomedicine, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, 31 Center Dr, Suite 1C14, Bethesda, MD, 20892-2281, USA.

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http://dx.doi.org/10.1007/s00726-010-0696-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3020998PMC
February 2011

Automated radiochemical synthesis of [18F]FBEM: a thiol reactive synthon for radiofluorination of peptides and proteins.

Appl Radiat Isot 2011 Feb 8;69(2):410-4. Epub 2010 Oct 8.

Laboratory of Molecular Imaging and Nanomedicine, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Building 10, Room 1C401, MSC 1180, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1016/j.apradiso.2010.09.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3010425PMC
February 2011

Applications of LC-MS in PET radioligand development and metabolic elucidation.

Curr Drug Metab 2010 Jul;11(6):483-93

Laboratory of Molecular Imaging and Nanomedicine (LOMIN), National Institute of Biomedical Imaging and Bioengineering (NIBIB), National Institutes of health (NIH), Bethesda, MD 20892, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3629981PMC
July 2010

Application of highly sensitive UPLC-MS to determine biodistribution at tracer doses: validation with the 5-HT1A ligand [(18)F]FPWAY.

Nucl Med Biol 2009 May 26;36(4):389-93. Epub 2009 Mar 26.

PET Radiochemistry Group, National Institute of Biomedical Imaging and Bioengineering (NIBIB), National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1016/j.nucmedbio.2009.01.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3644855PMC
May 2009

Distribution of the 5-HT(1A) receptor antagonist [ (18)F]FPWAY in blood and brain of the rat with and without isoflurane anesthesia.

Eur J Nucl Med Mol Imaging 2007 Feb 22;34(2):259-66. Epub 2006 Sep 22.

Positron Emission Tomography Department, Warren Grant Magnuson Clinical Center, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1007/s00259-006-0228-xDOI Listing
February 2007

Species differences in metabolites of PET ligands: serotonergic 5-HT1A receptor antagonists 3-trans-FCWAY and 3-cis-FCWAY.

Nucl Med Biol 2006 Nov;33(8):1013-9

PET Radiochemistry Group, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, MD 20892, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S096980510600193
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http://dx.doi.org/10.1016/j.nucmedbio.2006.09.006DOI Listing
November 2006

Synthesis and in vivo biodistribution of F-18 labeled 3-cis-, 3-trans-, 4-cis-, and 4-trans-fluorocyclohexane derivatives of WAY 100635.

Bioorg Med Chem 2006 Jun 20;14(11):3737-48. Epub 2006 Feb 20.

PET Department, Warren Grant Magnuson Clinical Center, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1016/j.bmc.2006.01.064DOI Listing
June 2006

Development of 5-HT1A receptor radioligands to determine receptor density and changes in endogenous 5-HT.

Synapse 2006 May;59(6):330-41

Positron Emission Tomography PET Department, Warren Grant Magnuson Clinical Center, National Institutes of Health, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1002/syn.20246DOI Listing
May 2006

Development of a controlled vocabulary and software application to analyze fruit shape variation in tomato and other plant species.

Plant Physiol 2006 May;141(1):15-25

Department of Horticulture and Crop Science, The Ohio State University/Ohio Agricultural Research and Development Center, Wooster, Ohio 44691, USA.

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http://dx.doi.org/10.1104/pp.106.077867DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1459328PMC
May 2006

Differential effects of paroxetine on raphe and cortical 5-HT1A binding: a PET study in monkeys.

Neuroimage 2005 Oct 1;28(1):238-48. Epub 2005 Jul 1.

PET Department, Clinical Center, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1016/j.neuroimage.2005.05.042DOI Listing
October 2005

Application of LC-MS to the analysis of new radiopharmaceuticals.

Mol Imaging Biol 2003 Nov-Dec;5(6):397-403

PET Department, Warren G. Magnuson Clinical Center, NIH, Bethesda, MD 20892, USA.

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November 2004

Purification of the precursor for the automated radiosynthesis of [18F]FCWAY by counter-current chromatography.

J Chromatogr A 2004 Apr;1034(1-2):149-53

PET Department, Warren Grant Magnuson Clinical Center, National Institutes of Health, Bldg 10, Rm 1C401, 10 Center Drive MSC 1180, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1016/j.chroma.2004.01.059DOI Listing
April 2004

Determination of [18F]FCWAY, [18F]FP-TZTP, and their metabolites in plasma using rapid and efficient liquid-liquid and solid phase extractions.

Nucl Med Biol 2003 Apr;30(3):233-40

PET Department, The Warren G Magnuson Clinical Center, National Institutes of Health, Bethesda, MD, USA.

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http://dx.doi.org/10.1016/s0969-8051(02)00452-3DOI Listing
April 2003

Brain uptake of the acid metabolites of F-18-labeled WAY 100635 analogs.

J Cereb Blood Flow Metab 2003 Feb;23(2):249-60

Positrom Emission Tomography Department, W.G. Magnuson Clinical Center, National Institutes of Health, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1097/01.WCB.0000046145.31247.7ADOI Listing
February 2003

Liquid chromatography-tandem mass spectrometry identification of metabolites of three phenylcarboxyl derivatives of the 5-HT(1A) antagonist, N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridyl) trans-4-fluorocyclohexanecarboxamide (FCWAY), produced by human and rat hepatocytes.

J Chromatogr B Analyt Technol Biomed Life Sci 2002 Nov;780(1):99-110

PET Department, Warren G Magnuson Clinical Center, National Institutes of Health, Bldg 10 Rm 1C401, 10 Center Drive MSC 1180, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1016/s1570-0232(02)00434-8DOI Listing
November 2002

Fluorine-18 labeled mouse bone marrow-derived dendritic cells can be detected in vivo by high resolution projection imaging.

J Immunol Methods 2002 Feb;260(1-2):137-48

Dermatology Branch, National Cancer Institute, National Institutes of Health, Bldg. 10, Room 12N238, 10 Center Drive, MSC 1908, Bethesda, MD 20892-1908, USA.

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http://dx.doi.org/10.1016/s0022-1759(01)00528-2DOI Listing
February 2002