Livia Garzia

Livia Garzia

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Livia Garzia

Livia Garzia

Publications by authors named "Livia Garzia"

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29Publications

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miR miR on the wall, who's the most malignant medulloblastoma miR of them all?

Neuro Oncol 2018 Feb;20(3):313-323

Developmental & Stem Cell Biology Program, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.

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February 2018

Tailoring Medulloblastoma Treatment Through Genomics: Making a Change, One Subgroup at a Time.

Annu Rev Genomics Hum Genet 2017 Aug 5;18:143-166. Epub 2017 May 5.

Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario M5G 1X8, Canada; email:

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August 2017

Intertumoral Heterogeneity within Medulloblastoma Subgroups.

Authors:
Florence M G Cavalli Marc Remke Ladislav Rampasek John Peacock David J H Shih Betty Luu Livia Garzia Jonathon Torchia Carolina Nor A Sorana Morrissy Sameer Agnihotri Yuan Yao Thompson Claudia M Kuzan-Fischer Hamza Farooq Keren Isaev Craig Daniels Byung-Kyu Cho Seung-Ki Kim Kyu-Chang Wang Ji Yeoun Lee Wieslawa A Grajkowska Marta Perek-Polnik Alexandre Vasiljevic Cecile Faure-Conter Anne Jouvet Caterina Giannini Amulya A Nageswara Rao Kay Ka Wai Li Ho-Keung Ng Charles G Eberhart Ian F Pollack Ronald L Hamilton G Yancey Gillespie James M Olson Sarah Leary William A Weiss Boleslaw Lach Lola B Chambless Reid C Thompson Michael K Cooper Rajeev Vibhakar Peter Hauser Marie-Lise C van Veelen Johan M Kros Pim J French Young Shin Ra Toshihiro Kumabe Enrique López-Aguilar Karel Zitterbart Jaroslav Sterba Gaetano Finocchiaro Maura Massimino Erwin G Van Meir Satoru Osuka Tomoko Shofuda Almos Klekner Massimo Zollo Jeffrey R Leonard Joshua B Rubin Nada Jabado Steffen Albrecht Jaume Mora Timothy E Van Meter Shin Jung Andrew S Moore Andrew R Hallahan Jennifer A Chan Daniela P C Tirapelli Carlos G Carlotti Maryam Fouladi José Pimentel Claudia C Faria Ali G Saad Luca Massimi Linda M Liau Helen Wheeler Hideo Nakamura Samer K Elbabaa Mario Perezpeña-Diazconti Fernando Chico Ponce de León Shenandoah Robinson Michal Zapotocky Alvaro Lassaletta Annie Huang Cynthia E Hawkins Uri Tabori Eric Bouffet Ute Bartels Peter B Dirks James T Rutka Gary D Bader Jüri Reimand Anna Goldenberg Vijay Ramaswamy Michael D Taylor

Cancer Cell 2017 06;31(6):737-754.e6

The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, ON M5G 1X8, Canada; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, ON M5G 1X8, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON M5S 1A1, Canada; Division of Neurosurgery, The Hospital for Sick Children, Toronto, ON M5G 1X8, Canada. Electronic address:

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June 2017

Integrated (epi)-Genomic Analyses Identify Subgroup-Specific Therapeutic Targets in CNS Rhabdoid Tumors.

Authors:
Jonathon Torchia Brian Golbourn Shengrui Feng King Ching Ho Patrick Sin-Chan Alexandre Vasiljevic Joseph D Norman Paul Guilhamon Livia Garzia Natalia R Agamez Mei Lu Tiffany S Chan Daniel Picard Pasqualino de Antonellis Dong-Anh Khuong-Quang Aline C Planello Constanze Zeller Dalia Barsyte-Lovejoy Lucie Lafay-Cousin Louis Letourneau Mathieu Bourgey Man Yu Deena M A Gendoo Misko Dzamba Mark Barszczyk Tiago Medina Alexandra N Riemenschneider A Sorana Morrissy Young-Shin Ra Vijay Ramaswamy Marc Remke Christopher P Dunham Stephen Yip Ho-Keung Ng Jian-Qiang Lu Vivek Mehta Steffen Albrecht Jose Pimentel Jennifer A Chan Gino R Somers Claudia C Faria Lucia Roque Maryam Fouladi Lindsey M Hoffman Andrew S Moore Yin Wang Seung Ah Choi Jordan R Hansford Daniel Catchpoole Diane K Birks Nicholas K Foreman Doug Strother Almos Klekner Laszló Bognár Miklós Garami Péter Hauser Tibor Hortobágyi Beverly Wilson Juliette Hukin Anne-Sophie Carret Timothy E Van Meter Eugene I Hwang Amar Gajjar Shih-Hwa Chiou Hideo Nakamura Helen Toledano Iris Fried Daniel Fults Takafumi Wataya Chris Fryer David D Eisenstat Katrin Scheinemann Adam J Fleming Donna L Johnston Jean Michaud Shayna Zelcer Robert Hammond Samina Afzal David A Ramsay Nongnuch Sirachainan Suradej Hongeng Noppadol Larbcharoensub Richard G Grundy Rishi R Lulla Jason R Fangusaro Harriet Druker Ute Bartels Ronald Grant David Malkin C Jane McGlade Theodore Nicolaides Tarik Tihan Joanna Phillips Jacek Majewski Alexandre Montpetit Guillaume Bourque Gary D Bader Alyssa T Reddy G Yancey Gillespie Monika Warmuth-Metz Stefan Rutkowski Uri Tabori Mathieu Lupien Michael Brudno Ulrich Schüller Torsten Pietsch Alexander R Judkins Cynthia E Hawkins Eric Bouffet Seung-Ki Kim Peter B Dirks Michael D Taylor Anat Erdreich-Epstein Cheryl H Arrowsmith Daniel D De Carvalho James T Rutka Nada Jabado Annie Huang

Cancer Cell 2016 Dec;30(6):891-908

Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON M5G0A4, Canada; Department of Paediatrics, University of Toronto, Toronto, ON M5G0A4, Canada; Division of Hematology/Oncology, Hospital for Sick Children, Toronto, ON M5G1X8, Canada; Arthur and Sonia Labatt Brain Tumour Research Centre, Hospital for Sick Children, Toronto, ON M5G1X8, Canada. Electronic address:

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December 2016

Prognostic value of medulloblastoma extent of resection after accounting for molecular subgroup: a retrospective integrated clinical and molecular analysis.

Authors:
Eric M Thompson Thomas Hielscher Eric Bouffet Marc Remke Betty Luu Sridharan Gururangan Roger E McLendon Darell D Bigner Eric S Lipp Sebastien Perreault Yoon-Jae Cho Gerald Grant Seung-Ki Kim Ji Yeoun Lee Amulya A Nageswara Rao Caterina Giannini Kay Ka Wai Li Ho-Keung Ng Yu Yao Toshihiro Kumabe Teiji Tominaga Wieslawa A Grajkowska Marta Perek-Polnik David C Y Low Wan Tew Seow Kenneth T E Chang Jaume Mora Ian F Pollack Ronald L Hamilton Sarah Leary Andrew S Moore Wendy J Ingram Andrew R Hallahan Anne Jouvet Michelle Fèvre-Montange Alexandre Vasiljevic Cecile Faure-Conter Tomoko Shofuda Naoki Kagawa Naoya Hashimoto Nada Jabado Alexander G Weil Tenzin Gayden Takafumi Wataya Tarek Shalaby Michael Grotzer Karel Zitterbart Jaroslav Sterba Leos Kren Tibor Hortobágyi Almos Klekner Bognár László Tímea Pócza Peter Hauser Ulrich Schüller Shin Jung Woo-Youl Jang Pim J French Johan M Kros Marie-Lise C van Veelen Luca Massimi Jeffrey R Leonard Joshua B Rubin Rajeev Vibhakar Lola B Chambless Michael K Cooper Reid C Thompson Claudia C Faria Alice Carvalho Sofia Nunes José Pimentel Xing Fan Karin M Muraszko Enrique López-Aguilar David Lyden Livia Garzia David J H Shih Noriyuki Kijima Christian Schneider Jennifer Adamski Paul A Northcott Marcel Kool David T W Jones Jennifer A Chan Ana Nikolic Maria Luisa Garre Erwin G Van Meir Satoru Osuka Jeffrey J Olson Arman Jahangiri Brandyn A Castro Nalin Gupta William A Weiss Iska Moxon-Emre Donald J Mabbott Alvaro Lassaletta Cynthia E Hawkins Uri Tabori James Drake Abhaya Kulkarni Peter Dirks James T Rutka Andrey Korshunov Stefan M Pfister Roger J Packer Vijay Ramaswamy Michael D Taylor

Lancet Oncol 2016 04 12;17(4):484-495. Epub 2016 Mar 12.

Division of Neurosurgery, The Hospital for Sick Children, Toronto, ON, Canada; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, ON, Canada; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, ON, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada. Electronic address:

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April 2016

Divergent clonal selection dominates medulloblastoma at recurrence.

Authors:
A Sorana Morrissy Livia Garzia David J H Shih Scott Zuyderduyn Xi Huang Patryk Skowron Marc Remke Florence M G Cavalli Vijay Ramaswamy Patricia E Lindsay Salomeh Jelveh Laura K Donovan Xin Wang Betty Luu Kory Zayne Yisu Li Chelsea Mayoh Nina Thiessen Eloi Mercier Karen L Mungall Yusanne Ma Kane Tse Thomas Zeng Karey Shumansky Andrew J L Roth Sohrab Shah Hamza Farooq Noriyuki Kijima Borja L Holgado John J Y Lee Stuart Matan-Lithwick Jessica Liu Stephen C Mack Alex Manno K A Michealraj Carolina Nor John Peacock Lei Qin Juri Reimand Adi Rolider Yuan Y Thompson Xiaochong Wu Trevor Pugh Adrian Ally Mikhail Bilenky Yaron S N Butterfield Rebecca Carlsen Young Cheng Eric Chuah Richard D Corbett Noreen Dhalla An He Darlene Lee Haiyan I Li William Long Michael Mayo Patrick Plettner Jenny Q Qian Jacqueline E Schein Angela Tam Tina Wong Inanc Birol Yongjun Zhao Claudia C Faria José Pimentel Sofia Nunes Tarek Shalaby Michael Grotzer Ian F Pollack Ronald L Hamilton Xiao-Nan Li Anne E Bendel Daniel W Fults Andrew W Walter Toshihiro Kumabe Teiji Tominaga V Peter Collins Yoon-Jae Cho Caitlin Hoffman David Lyden Jeffrey H Wisoff James H Garvin Duncan S Stearns Luca Massimi Ulrich Schüller Jaroslav Sterba Karel Zitterbart Stephanie Puget Olivier Ayrault Sandra E Dunn Daniela P C Tirapelli Carlos G Carlotti Helen Wheeler Andrew R Hallahan Wendy Ingram Tobey J MacDonald Jeffrey J Olson Erwin G Van Meir Ji-Yeoun Lee Kyu-Chang Wang Seung-Ki Kim Byung-Kyu Cho Torsten Pietsch Gudrun Fleischhack Stephan Tippelt Young Shin Ra Simon Bailey Janet C Lindsey Steven C Clifford Charles G Eberhart Michael K Cooper Roger J Packer Maura Massimino Maria Luisa Garre Ute Bartels Uri Tabori Cynthia E Hawkins Peter Dirks Eric Bouffet James T Rutka Robert J Wechsler-Reya William A Weiss Lara S Collier Adam J Dupuy Andrey Korshunov David T W Jones Marcel Kool Paul A Northcott Stefan M Pfister David A Largaespada Andrew J Mungall Richard A Moore Nada Jabado Gary D Bader Steven J M Jones David Malkin Marco A Marra Michael D Taylor

Nature 2016 Jan 13;529(7586):351-7. Epub 2016 Jan 13.

Developmental &Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario M5G 0A4, Canada.

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January 2016

Poly-ADP-Ribose Polymerase as a Therapeutic Target in Pediatric Diffuse Intrinsic Pontine Glioma and Pediatric High-Grade Astrocytoma.

Mol Cancer Ther 2015 Nov 8;14(11):2560-8. Epub 2015 Sep 8.

Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada. Department of Laboratory Medicine and Pathobiology, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada. Division of Pathology, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.

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November 2015

Measuring the optical characteristics of medulloblastoma with optical coherence tomography.

Biomed Opt Express 2015 Apr 25;6(4):1487-501. Epub 2015 Mar 25.

Biophotonics and Bioengineering Laboratory, Ryerson University, 350 Victoria Street, Toronto, ON, M5B 2K3, Canada ; Division of Neurosurgery, Faculty of Medicine, University of Toronto, 1 King's College Circle, Toronto, ON, M5S 1A8, Canada ; Physical Science - Brain Sciences Research Program, Sunnybrook Research Institute, 2075 Bayview Avenue, Toronto, ON, M4N 3M5, Canada ; Division of Neurosurgery, Sunnybrook Health Sciences Centre, 2075 Bayview Avenue Toronto, ON, M4N 3M5, Canada.

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April 2015

Foretinib is effective therapy for metastatic sonic hedgehog medulloblastoma.

Cancer Res 2015 Jan 12;75(1):134-46. Epub 2014 Nov 12.

Arthur and Sonia Labatt Brain Tumour Research Centre, Hospital for Sick Children, Toronto, Canada. Division of Neurosurgery, Hospital for Sick Children, Toronto, Canada. Department of Surgery, University of Toronto, Toronto, Canada.

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January 2015

Cytogenetic prognostication within medulloblastoma subgroups.

J Clin Oncol 2014 Mar 3;32(9):886-96. Epub 2014 Feb 3.

David J.H. Shih, Marc Remke, Vijay Ramaswamy, Betty Luu, Yuan Yao, Xin Wang, Adrian M. Dubuc, Livia Garzia, John Peacock, Stephen C. Mack, Xiaochong Wu, Adi Rolider, A. Sorana Morrissy, Florence M.G. Cavalli, Claudia C. Faria, Stephen W. Scherer, Uri Tabori, Cynthia E. Hawkins, David Malkin, Eric Bouffet, James T. Rutka, and Michael D. Taylor, Hospital for Sick Children; David J.H. Shih, Marc Remke, Vijay Ramaswamy, Yuan Yao, Xin Wang, Adrian M. Dubuc, John Peacock, Stephen C. Mack, and Michael D. Taylor, University of Toronto, Toronto; Boleslaw Lach, McMaster University, Hamilton, Ontario; Jennifer A. Chan, University of Calgary, Calgary, Alberta; Steffen Albrecht, Adam Fontebasso, and Nada Jabado, McGill University, Montreal, Quebec, Canada; Paul A. Northcott, Andrey Korshunov, Marcel Kool, David T.W. Jones, and Stefan M. Pfister, German Cancer Research Center; Stefan M. Pfister, University Hospital Heidelberg, Heidelberg; Ulrich Schüller, Ludwig-Maximilians-University, Munich; Stefan Rutkowski, University Medical Center Hamburg-Eppendorf, Hamburg, Germany; Karel Zitterbart, Masaryk University School of Medicine; Karel Zitterbart and Leos Kren, University Hospital Brno, Brno, Czech Republic; Toshihiro Kumabe and Teiji Tominaga, Tohoku University Graduate School of Medicine, Sendai, Japan; Young Shin Ra, University of Ulsan, Asan Medical Center; Ji-Yeoun Lee, Byung-Kyu Cho, Seung-Ki Kim, and Kyu-Chang Wang, Seoul National University Children's Hospital, Seoul; Shin Jung, Chonnam National University Research Institute of Medical Sciences, Chonnam National University Hwasun Hospital and Medical School, Chonnam, South Korea; Peter Hauser and Miklós Garami, Semmelweis University, Budapest; László Bognár and Almos Klekner, University of Debrecen, Medical and Health Science Centre, Debrecen, Hungary; Shenandoah Robinson, Boston Children's Hospital; Scott L. Pomeroy, Harvard Medical School, Boston, MA; Ali G. Saad, University of Arkansas for Medical Sciences, Little

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March 2014

TERT promoter mutations are highly recurrent in SHH subgroup medulloblastoma.

Acta Neuropathol 2013 Dec 31;126(6):917-29. Epub 2013 Oct 31.

The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, ON, Canada.

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December 2013

Spatial and temporal expressions of prune reveal a role in Müller gliogenesis during Xenopus retinal development.

Gene 2012 Nov 15;509(1):93-103. Epub 2012 Aug 15.

UCL Institute of Ophthalmology, University College London, 11-43 Bath Street, London EC1V 9EL, UK.

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November 2012

Subgroup-specific structural variation across 1,000 medulloblastoma genomes.

Authors:
Paul A Northcott David J H Shih John Peacock Livia Garzia A Sorana Morrissy Thomas Zichner Adrian M Stütz Andrey Korshunov Jüri Reimand Steven E Schumacher Rameen Beroukhim David W Ellison Christian R Marshall Anath C Lionel Stephen Mack Adrian Dubuc Yuan Yao Vijay Ramaswamy Betty Luu Adi Rolider Florence M G Cavalli Xin Wang Marc Remke Xiaochong Wu Readman Y B Chiu Andy Chu Eric Chuah Richard D Corbett Gemma R Hoad Shaun D Jackman Yisu Li Allan Lo Karen L Mungall Ka Ming Nip Jenny Q Qian Anthony G J Raymond Nina T Thiessen Richard J Varhol Inanc Birol Richard A Moore Andrew J Mungall Robert Holt Daisuke Kawauchi Martine F Roussel Marcel Kool David T W Jones Hendrick Witt Africa Fernandez-L Anna M Kenney Robert J Wechsler-Reya Peter Dirks Tzvi Aviv Wieslawa A Grajkowska Marta Perek-Polnik Christine C Haberler Olivier Delattre Stéphanie S Reynaud François F Doz Sarah S Pernet-Fattet Byung-Kyu Cho Seung-Ki Kim Kyu-Chang Wang Wolfram Scheurlen Charles G Eberhart Michelle Fèvre-Montange Anne Jouvet Ian F Pollack Xing Fan Karin M Muraszko G Yancey Gillespie Concezio Di Rocco Luca Massimi Erna M C Michiels Nanne K Kloosterhof Pim J French Johan M Kros James M Olson Richard G Ellenbogen Karel Zitterbart Leos Kren Reid C Thompson Michael K Cooper Boleslaw Lach Roger E McLendon Darell D Bigner Adam Fontebasso Steffen Albrecht Nada Jabado Janet C Lindsey Simon Bailey Nalin Gupta William A Weiss László Bognár Almos Klekner Timothy E Van Meter Toshihiro Kumabe Teiji Tominaga Samer K Elbabaa Jeffrey R Leonard Joshua B Rubin Linda M Liau Erwin G Van Meir Maryam Fouladi Hideo Nakamura Giuseppe Cinalli Miklós Garami Peter Hauser Ali G Saad Achille Iolascon Shin Jung Carlos G Carlotti Rajeev Vibhakar Young Shin Ra Shenandoah Robinson Massimo Zollo Claudia C Faria Jennifer A Chan Michael L Levy Poul H B Sorensen Matthew Meyerson Scott L Pomeroy Yoon-Jae Cho Gary D Bader Uri Tabori Cynthia E Hawkins Eric Bouffet Stephen W Scherer James T Rutka David Malkin Steven C Clifford Steven J M Jones Jan O Korbel Stefan M Pfister Marco A Marra Michael D Taylor

Nature 2012 Aug;488(7409):49-56

Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario M5G 1L7, Canada.

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August 2012

PCDH10 is a candidate tumour suppressor gene in medulloblastoma.

Childs Nerv Syst 2011 Aug 20;27(8):1243-9. Epub 2011 May 20.

Division of Neurosurgery, Arthur and Sonia Labatt Brain Tumor Research Centre, Program in Developmental and Stem Cell Biology, Hospital for Sick Children, Toronto, ON, M4N 1X8, Canada.

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August 2011

Domain mapping on the human metastasis regulator protein h-Prune reveals a C-terminal dimerization domain.

Biochem J 2007 Oct;407(2):199-205

Department of Physiological Chemistry, Ruhr-University Bochum, Universitätsstrasse 150, 44801 Bochum, Germany.

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October 2007

H-prune-nm23-H1 protein complex and correlation to pathways in cancer metastasis.

J Bioenerg Biomembr 2006 Aug;38(3-4):205-13

Centro di Ingegneria Genetica e Biotecnologia Avanzate, CEINGE, Via Comunale Margherita 482, 80131, Naples, Italy.

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August 2006