Lisette Stolk

Lisette Stolk

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Lisette Stolk

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Disentangling the genetics of lean mass.

Authors:
David Karasik M Carola Zillikens Yi-Hsiang Hsu Ali Aghdassi Kristina Akesson Najaf Amin Inês Barroso David A Bennett Lars Bertram Murielle Bochud Ingrid B Borecki Linda Broer Aron S Buchman Liisa Byberg Harry Campbell Natalia Campos-Obando Jane A Cauley Peggy M Cawthon John C Chambers Zhao Chen Nam H Cho Hyung Jin Choi Wen-Chi Chou Steven R Cummings Lisette C P G M de Groot Phillip L De Jager Ilja Demuth Luda Diatchenko Michael J Econs Gudny Eiriksdottir Anke W Enneman Joel Eriksson Johan G Eriksson Karol Estrada Daniel S Evans Mary F Feitosa Mao Fu Christian Gieger Harald Grallert Vilmundur Gudnason Launer J Lenore Caroline Hayward Albert Hofman Georg Homuth Kim M Huffman Lise B Husted Thomas Illig Erik Ingelsson Till Ittermann John-Olov Jansson Toby Johnson Reiner Biffar Joanne M Jordan Antti Jula Magnus Karlsson Kay-Tee Khaw Tuomas O Kilpeläinen Norman Klopp Jacqueline S L Kloth Daniel L Koller Jaspal S Kooner William E Kraus Stephen Kritchevsky Zoltán Kutalik Teemu Kuulasmaa Johanna Kuusisto Markku Laakso Jari Lahti Thomas Lang Bente L Langdahl Markus M Lerch Joshua R Lewis Christina Lill Lars Lind Cecilia Lindgren Yongmei Liu Gregory Livshits Östen Ljunggren Ruth J F Loos Mattias Lorentzon Jian'an Luan Robert N Luben Ida Malkin Fiona E McGuigan Carolina Medina-Gomez Thomas Meitinger Håkan Melhus Dan Mellström Karl Michaëlsson Braxton D Mitchell Andrew P Morris Leif Mosekilde Maria Nethander Anne B Newman Jeffery R O'Connell Ben A Oostra Eric S Orwoll Aarno Palotie Munro Peacock Markus Perola Annette Peters Richard L Prince Bruce M Psaty Katri Räikkönen Stuart H Ralston Samuli Ripatti Fernando Rivadeneira John A Robbins Jerome I Rotter Igor Rudan Veikko Salomaa Suzanne Satterfield Sabine Schipf Chan Soo Shin Albert V Smith Shad B Smith Nicole Soranzo Timothy D Spector Alena Stancáková Kari Stefansson Elisabeth Steinhagen-Thiessen Lisette Stolk Elizabeth A Streeten Unnur Styrkarsdottir Karin M A Swart Patricia Thompson Cynthia A Thomson Gudmar Thorleifsson Unnur Thorsteinsdottir Emmi Tikkanen Gregory J Tranah André G Uitterlinden Cornelia M van Duijn Natasja M van Schoor Liesbeth Vandenput Peter Vollenweider Henry Völzke Jean Wactawski-Wende Mark Walker Nicholas J Wareham Dawn Waterworth Michael N Weedon H-Erich Wichmann Elisabeth Widen Frances M K Williams James F Wilson Nicole C Wright Laura M Yerges-Armstrong Lei Yu Weihua Zhang Jing Hua Zhao Yanhua Zhou Carrie M Nielson Tamara B Harris Serkalem Demissie Douglas P Kiel Claes Ohlsson

Am J Clin Nutr 2019 02;109(2):276-287

Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

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http://dx.doi.org/10.1093/ajcn/nqy272DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6500901PMC
February 2019

Multi-ethnic SULT1A1 copy number profiling with multiplex ligation-dependent probe amplification.

Pharmacogenomics 2018 06 23;19(9):761-770. Epub 2018 May 23.

Department of Genetics & Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.

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http://dx.doi.org/10.2217/pgs-2018-0047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6021911PMC
June 2018

Erratum: Large meta-analysis of genome-wide association studies identifies five loci for lean body mass.

Authors:
M Carola Zillikens Serkalem Demissie Yi-Hsiang Hsu Laura M Yerges-Armstrong Wen-Chi Chou Lisette Stolk Gregory Livshits Linda Broer Toby Johnson Daniel L Koller Zoltán Kutalik Jian'an Luan Ida Malkin Janina S Ried Albert V Smith Gudmar Thorleifsson Liesbeth Vandenput Jing Hua Zhao Weihua Zhang Ali Aghdassi Kristina Åkesson Najaf Amin Leslie J Baier Inês Barroso David A Bennett Lars Bertram Rainer Biffar Murielle Bochud Michael Boehnke Ingrid B Borecki Aron S Buchman Liisa Byberg Harry Campbell Natalia Campos Obanda Jane A Cauley Peggy M Cawthon Henna Cederberg Zhao Chen Nam H Cho Hyung Jin Choi Melina Claussnitzer Francis Collins Steven R Cummings Philip L De Jager Ilja Demuth Rosalie A M Dhonukshe-Rutten Luda Diatchenko Gudny Eiriksdottir Anke W Enneman Mike Erdos Johan G Eriksson Joel Eriksson Karol Estrada Daniel S Evans Mary F Feitosa Mao Fu Melissa Garcia Christian Gieger Thomas Girke Nicole L Glazer Harald Grallert Jagvir Grewal Bok-Ghee Han Robert L Hanson Caroline Hayward Albert Hofman Eric P Hoffman Georg Homuth Wen-Chi Hsueh Monica J Hubal Alan Hubbard Kim M Huffman Lise B Husted Thomas Illig Erik Ingelsson Till Ittermann John-Olov Jansson Joanne M Jordan Antti Jula Magnus Karlsson Kay-Tee Khaw Tuomas O Kilpeläinen Norman Klopp Jacqueline S L Kloth Heikki A Koistinen William E Kraus Stephen Kritchevsky Teemu Kuulasmaa Johanna Kuusisto Markku Laakso Jari Lahti Thomas Lang Bente L Langdahl Lenore J Launer Jong-Young Lee Markus M Lerch Joshua R Lewis Lars Lind Cecilia Lindgren Yongmei Liu Tian Liu Youfang Liu Östen Ljunggren Mattias Lorentzon Robert N Luben William Maixner Fiona E McGuigan Carolina Medina-Gomez Thomas Meitinger Håkan Melhus Dan Mellström Simon Melov Karl Michaëlsson Braxton D Mitchell Andrew P Morris Leif Mosekilde Anne Newman Carrie M Nielson Jeffrey R O'Connell Ben A Oostra Eric S Orwoll Aarno Palotie Stephen C J Parker Munro Peacock Markus Perola Annette Peters Ozren Polasek Richard L Prince Katri Räikkönen Stuart H Ralston Samuli Ripatti John A Robbins Jerome I Rotter Igor Rudan Veikko Salomaa Suzanne Satterfield Eric E Schadt Sabine Schipf Laura Scott Joban Sehmi Jian Shen Chan Soo Shin Gunnar Sigurdsson Shad Smith Nicole Soranzo Alena Stančáková Elisabeth Steinhagen-Thiessen Elizabeth A Streeten Unnur Styrkarsdottir Karin M A Swart Sian-Tsung Tan Mark A Tarnopolsky Patricia Thompson Cynthia A Thomson Unnur Thorsteinsdottir Emmi Tikkanen Gregory J Tranah Jaakko Tuomilehto Natasja M van Schoor Arjun Verma Peter Vollenweider Henry Völzke Jean Wactawski-Wende Mark Walker Michael N Weedon Ryan Welch H-Erich Wichmann Elisabeth Widen Frances M K Williams James F Wilson Nicole C Wright Weijia Xie Lei Yu Yanhua Zhou John C Chambers Angela Döring Cornelia M van Duijn Michael J Econs Vilmundur Gudnason Jaspal S Kooner Bruce M Psaty Timothy D Spector Kari Stefansson Fernando Rivadeneira André G Uitterlinden Nicholas J Wareham Vicky Ossowski Dawn Waterworth Ruth J F Loos David Karasik Tamara B Harris Claes Ohlsson Douglas P Kiel

Nat Commun 2017 11 7;8(1):1414. Epub 2017 Nov 7.

Hebrew SeniorLife, Institute for Aging Research, Roslindale, MA, 02131, USA.

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http://dx.doi.org/10.1038/s41467-017-01008-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5676783PMC
November 2017

Large meta-analysis of genome-wide association studies identifies five loci for lean body mass.

Authors:
M Carola Zillikens Serkalem Demissie Yi-Hsiang Hsu Laura M Yerges-Armstrong Wen-Chi Chou Lisette Stolk Gregory Livshits Linda Broer Toby Johnson Daniel L Koller Zoltán Kutalik Jian'an Luan Ida Malkin Janina S Ried Albert V Smith Gudmar Thorleifsson Liesbeth Vandenput Jing Hua Zhao Weihua Zhang Ali Aghdassi Kristina Åkesson Najaf Amin Leslie J Baier Inês Barroso David A Bennett Lars Bertram Rainer Biffar Murielle Bochud Michael Boehnke Ingrid B Borecki Aron S Buchman Liisa Byberg Harry Campbell Natalia Campos Obanda Jane A Cauley Peggy M Cawthon Henna Cederberg Zhao Chen Nam H Cho Hyung Jin Choi Melina Claussnitzer Francis Collins Steven R Cummings Philip L De Jager Ilja Demuth Rosalie A M Dhonukshe-Rutten Luda Diatchenko Gudny Eiriksdottir Anke W Enneman Mike Erdos Johan G Eriksson Joel Eriksson Karol Estrada Daniel S Evans Mary F Feitosa Mao Fu Melissa Garcia Christian Gieger Thomas Girke Nicole L Glazer Harald Grallert Jagvir Grewal Bok-Ghee Han Robert L Hanson Caroline Hayward Albert Hofman Eric P Hoffman Georg Homuth Wen-Chi Hsueh Monica J Hubal Alan Hubbard Kim M Huffman Lise B Husted Thomas Illig Erik Ingelsson Till Ittermann John-Olov Jansson Joanne M Jordan Antti Jula Magnus Karlsson Kay-Tee Khaw Tuomas O Kilpeläinen Norman Klopp Jacqueline S L Kloth Heikki A Koistinen William E Kraus Stephen Kritchevsky Teemu Kuulasmaa Johanna Kuusisto Markku Laakso Jari Lahti Thomas Lang Bente L Langdahl Lenore J Launer Jong-Young Lee Markus M Lerch Joshua R Lewis Lars Lind Cecilia Lindgren Yongmei Liu Tian Liu Youfang Liu Östen Ljunggren Mattias Lorentzon Robert N Luben William Maixner Fiona E McGuigan Carolina Medina-Gomez Thomas Meitinger Håkan Melhus Dan Mellström Simon Melov Karl Michaëlsson Braxton D Mitchell Andrew P Morris Leif Mosekilde Anne Newman Carrie M Nielson Jeffrey R O'Connell Ben A Oostra Eric S Orwoll Aarno Palotie Stephen C J Parker Munro Peacock Markus Perola Annette Peters Ozren Polasek Richard L Prince Katri Räikkönen Stuart H Ralston Samuli Ripatti John A Robbins Jerome I Rotter Igor Rudan Veikko Salomaa Suzanne Satterfield Eric E Schadt Sabine Schipf Laura Scott Joban Sehmi Jian Shen Chan Soo Shin Gunnar Sigurdsson Shad Smith Nicole Soranzo Alena Stančáková Elisabeth Steinhagen-Thiessen Elizabeth A Streeten Unnur Styrkarsdottir Karin M A Swart Sian-Tsung Tan Mark A Tarnopolsky Patricia Thompson Cynthia A Thomson Unnur Thorsteinsdottir Emmi Tikkanen Gregory J Tranah Jaakko Tuomilehto Natasja M van Schoor Arjun Verma Peter Vollenweider Henry Völzke Jean Wactawski-Wende Mark Walker Michael N Weedon Ryan Welch H-Erich Wichmann Elisabeth Widen Frances M K Williams James F Wilson Nicole C Wright Weijia Xie Lei Yu Yanhua Zhou John C Chambers Angela Döring Cornelia M van Duijn Michael J Econs Vilmundur Gudnason Jaspal S Kooner Bruce M Psaty Timothy D Spector Kari Stefansson Fernando Rivadeneira André G Uitterlinden Nicholas J Wareham Vicky Ossowski Dawn Waterworth Ruth J F Loos David Karasik Tamara B Harris Claes Ohlsson Douglas P Kiel

Nat Commun 2017 07 19;8(1):80. Epub 2017 Jul 19.

Hebrew SeniorLife, Institute for Aging Research, Roslindale, MA, 02131, USA.

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http://dx.doi.org/10.1038/s41467-017-00031-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5517526PMC
July 2017

Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk.

Authors:
Felix R Day Deborah J Thompson Hannes Helgason Daniel I Chasman Hilary Finucane Patrick Sulem Katherine S Ruth Sean Whalen Abhishek K Sarkar Eva Albrecht Elisabeth Altmaier Marzyeh Amini Caterina M Barbieri Thibaud Boutin Archie Campbell Ellen Demerath Ayush Giri Chunyan He Jouke J Hottenga Robert Karlsson Ivana Kolcic Po-Ru Loh Kathryn L Lunetta Massimo Mangino Brumat Marco George McMahon Sarah E Medland Ilja M Nolte Raymond Noordam Teresa Nutile Lavinia Paternoster Natalia Perjakova Eleonora Porcu Lynda M Rose Katharina E Schraut Ayellet V Segrè Albert V Smith Lisette Stolk Alexander Teumer Irene L Andrulis Stefania Bandinelli Matthias W Beckmann Javier Benitez Sven Bergmann Murielle Bochud Eric Boerwinkle Stig E Bojesen Manjeet K Bolla Judith S Brand Hiltrud Brauch Hermann Brenner Linda Broer Thomas Brüning Julie E Buring Harry Campbell Eulalia Catamo Stephen Chanock Georgia Chenevix-Trench Tanguy Corre Fergus J Couch Diana L Cousminer Angela Cox Laura Crisponi Kamila Czene George Davey Smith Eco J C N de Geus Renée de Mutsert Immaculata De Vivo Joe Dennis Peter Devilee Isabel Dos-Santos-Silva Alison M Dunning Johan G Eriksson Peter A Fasching Lindsay Fernández-Rhodes Luigi Ferrucci Dieter Flesch-Janys Lude Franke Marike Gabrielson Ilaria Gandin Graham G Giles Harald Grallert Daniel F Gudbjartsson Pascal Guénel Per Hall Emily Hallberg Ute Hamann Tamara B Harris Catharina A Hartman Gerardo Heiss Maartje J Hooning John L Hopper Frank Hu David J Hunter M Arfan Ikram Hae Kyung Im Marjo-Riitta Järvelin Peter K Joshi David Karasik Manolis Kellis Zoltan Kutalik Genevieve LaChance Diether Lambrechts Claudia Langenberg Lenore J Launer Joop S E Laven Stefania Lenarduzzi Jingmei Li Penelope A Lind Sara Lindstrom YongMei Liu Jian'an Luan Reedik Mägi Arto Mannermaa Hamdi Mbarek Mark I McCarthy Christa Meisinger Thomas Meitinger Cristina Menni Andres Metspalu Kyriaki Michailidou Lili Milani Roger L Milne Grant W Montgomery Anna M Mulligan Mike A Nalls Pau Navarro Heli Nevanlinna Dale R Nyholt Albertine J Oldehinkel Tracy A O'Mara Sandosh Padmanabhan Aarno Palotie Nancy Pedersen Annette Peters Julian Peto Paul D P Pharoah Anneli Pouta Paolo Radice Iffat Rahman Susan M Ring Antonietta Robino Frits R Rosendaal Igor Rudan Rico Rueedi Daniela Ruggiero Cinzia F Sala Marjanka K Schmidt Robert A Scott Mitul Shah Rossella Sorice Melissa C Southey Ulla Sovio Meir Stampfer Maristella Steri Konstantin Strauch Toshiko Tanaka Emmi Tikkanen Nicholas J Timpson Michela Traglia Thérèse Truong Jonathan P Tyrer André G Uitterlinden Digna R Velez Edwards Veronique Vitart Uwe Völker Peter Vollenweider Qin Wang Elisabeth Widen Ko Willems van Dijk Gonneke Willemsen Robert Winqvist Bruce H R Wolffenbuttel Jing Hua Zhao Magdalena Zoledziewska Marek Zygmunt Behrooz Z Alizadeh Dorret I Boomsma Marina Ciullo Francesco Cucca Tõnu Esko Nora Franceschini Christian Gieger Vilmundur Gudnason Caroline Hayward Peter Kraft Debbie A Lawlor Patrik K E Magnusson Nicholas G Martin Dennis O Mook-Kanamori Ellen A Nohr Ozren Polasek David Porteous Alkes L Price Paul M Ridker Harold Snieder Tim D Spector Doris Stöckl Daniela Toniolo Sheila Ulivi Jenny A Visser Henry Völzke Nicholas J Wareham James F Wilson Amanda B Spurdle Unnur Thorsteindottir Katherine S Pollard Douglas F Easton Joyce Y Tung Jenny Chang-Claude David Hinds Anna Murray Joanne M Murabito Kari Stefansson Ken K Ong John R B Perry

Nat Genet 2017 Jun 24;49(6):834-841. Epub 2017 Apr 24.

MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, UK.

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http://dx.doi.org/10.1038/ng.3841DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5841952PMC
June 2017

Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity.

Authors:
Simone Wahl Alexander Drong Benjamin Lehne Marie Loh William R Scott Sonja Kunze Pei-Chien Tsai Janina S Ried Weihua Zhang Youwen Yang Sili Tan Giovanni Fiorito Lude Franke Simonetta Guarrera Silva Kasela Jennifer Kriebel Rebecca C Richmond Marco Adamo Uzma Afzal Mika Ala-Korpela Benedetta Albetti Ole Ammerpohl Jane F Apperley Marian Beekman Pier Alberto Bertazzi S Lucas Black Christine Blancher Marc-Jan Bonder Mario Brosch Maren Carstensen-Kirberg Anton J M de Craen Simon de Lusignan Abbas Dehghan Mohamed Elkalaawy Krista Fischer Oscar H Franco Tom R Gaunt Jochen Hampe Majid Hashemi Aaron Isaacs Andrew Jenkinson Sujeet Jha Norihiro Kato Vittorio Krogh Michael Laffan Christa Meisinger Thomas Meitinger Zuan Yu Mok Valeria Motta Hong Kiat Ng Zacharoula Nikolakopoulou Georgios Nteliopoulos Salvatore Panico Natalia Pervjakova Holger Prokisch Wolfgang Rathmann Michael Roden Federica Rota Michelle Ann Rozario Johanna K Sandling Clemens Schafmayer Katharina Schramm Reiner Siebert P Eline Slagboom Pasi Soininen Lisette Stolk Konstantin Strauch E-Shyong Tai Letizia Tarantini Barbara Thorand Ettje F Tigchelaar Rosario Tumino Andre G Uitterlinden Cornelia van Duijn Joyce B J van Meurs Paolo Vineis Ananda Rajitha Wickremasinghe Cisca Wijmenga Tsun-Po Yang Wei Yuan Alexandra Zhernakova Rachel L Batterham George Davey Smith Panos Deloukas Bastiaan T Heijmans Christian Herder Albert Hofman Cecilia M Lindgren Lili Milani Pim van der Harst Annette Peters Thomas Illig Caroline L Relton Melanie Waldenberger Marjo-Riitta Järvelin Valentina Bollati Richie Soong Tim D Spector James Scott Mark I McCarthy Paul Elliott Jordana T Bell Giuseppe Matullo Christian Gieger Jaspal S Kooner Harald Grallert John C Chambers

Nature 2017 01 21;541(7635):81-86. Epub 2016 Dec 21.

Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College London, London W2 1PG, UK.

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http://dx.doi.org/10.1038/nature20784DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5570525PMC
January 2017

Genetic variation and bone mineral density in long-term adult survivors of childhood cancer.

Pediatr Blood Cancer 2016 12 31;63(12):2212-2220. Epub 2016 Aug 31.

Department of Pediatric Oncology/Hematology, Erasmus MC-Sophia Children's Hospital Rotterdam, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1002/pbc.26198DOI Listing
December 2016

Genome-wide analysis identifies 12 loci influencing human reproductive behavior.

Authors:
Nicola Barban Rick Jansen Ronald de Vlaming Ahmad Vaez Jornt J Mandemakers Felix C Tropf Xia Shen James F Wilson Daniel I Chasman Ilja M Nolte Vinicius Tragante Sander W van der Laan John R B Perry Augustine Kong Tarunveer S Ahluwalia Eva Albrecht Laura Yerges-Armstrong Gil Atzmon Kirsi Auro Kristin Ayers Andrew Bakshi Danny Ben-Avraham Klaus Berger Aviv Bergman Lars Bertram Lawrence F Bielak Gyda Bjornsdottir Marc Jan Bonder Linda Broer Minh Bui Caterina Barbieri Alana Cavadino Jorge E Chavarro Constance Turman Maria Pina Concas Heather J Cordell Gail Davies Peter Eibich Nicholas Eriksson Tõnu Esko Joel Eriksson Fahimeh Falahi Janine F Felix Mark Alan Fontana Lude Franke Ilaria Gandin Audrey J Gaskins Christian Gieger Erica P Gunderson Xiuqing Guo Caroline Hayward Chunyan He Edith Hofer Hongyan Huang Peter K Joshi Stavroula Kanoni Robert Karlsson Stefan Kiechl Annette Kifley Alexander Kluttig Peter Kraft Vasiliki Lagou Cecile Lecoeur Jari Lahti Ruifang Li-Gao Penelope A Lind Tian Liu Enes Makalic Crysovalanto Mamasoula Lindsay Matteson Hamdi Mbarek Patrick F McArdle George McMahon S Fleur W Meddens Evelin Mihailov Mike Miller Stacey A Missmer Claire Monnereau Peter J van der Most Ronny Myhre Mike A Nalls Teresa Nutile Ioanna Panagiota Kalafati Eleonora Porcu Inga Prokopenko Kumar B Rajan Janet Rich-Edwards Cornelius A Rietveld Antonietta Robino Lynda M Rose Rico Rueedi Kathleen A Ryan Yasaman Saba Daniel Schmidt Jennifer A Smith Lisette Stolk Elizabeth Streeten Anke Tönjes Gudmar Thorleifsson Sheila Ulivi Juho Wedenoja Juergen Wellmann Peter Willeit Jie Yao Loic Yengo Jing Hua Zhao Wei Zhao Daria V Zhernakova Najaf Amin Howard Andrews Beverley Balkau Nir Barzilai Sven Bergmann Ginevra Biino Hans Bisgaard Klaus Bønnelykke Dorret I Boomsma Julie E Buring Harry Campbell Stefania Cappellani Marina Ciullo Simon R Cox Francesco Cucca Daniela Toniolo George Davey-Smith Ian J Deary George Dedoussis Panos Deloukas Cornelia M van Duijn Eco J C de Geus Johan G Eriksson Denis A Evans Jessica D Faul Cinzia Felicita Sala Philippe Froguel Paolo Gasparini Giorgia Girotto Hans-Jörgen Grabe Karin Halina Greiser Patrick J F Groenen Hugoline G de Haan Johannes Haerting Tamara B Harris Andrew C Heath Kauko Heikkilä Albert Hofman Georg Homuth Elizabeth G Holliday John Hopper Elina Hyppönen Bo Jacobsson Vincent W V Jaddoe Magnus Johannesson Astanand Jugessur Mika Kähönen Eero Kajantie Sharon L R Kardia Bernard Keavney Ivana Kolcic Päivikki Koponen Peter Kovacs Florian Kronenberg Zoltan Kutalik Martina La Bianca Genevieve Lachance William G Iacono Sandra Lai Terho Lehtimäki David C Liewald Cecilia M Lindgren Yongmei Liu Robert Luben Michael Lucht Riitta Luoto Per Magnus Patrik K E Magnusson Nicholas G Martin Matt McGue Ruth McQuillan Sarah E Medland Christa Meisinger Dan Mellström Andres Metspalu Michela Traglia Lili Milani Paul Mitchell Grant W Montgomery Dennis Mook-Kanamori Renée de Mutsert Ellen A Nohr Claes Ohlsson Jørn Olsen Ken K Ong Lavinia Paternoster Alison Pattie Brenda W J H Penninx Markus Perola Patricia A Peyser Mario Pirastu Ozren Polasek Chris Power Jaakko Kaprio Leslie J Raffel Katri Räikkönen Olli Raitakari Paul M Ridker Susan M Ring Kathryn Roll Igor Rudan Daniela Ruggiero Dan Rujescu Veikko Salomaa David Schlessinger Helena Schmidt Reinhold Schmidt Nicole Schupf Johannes Smit Rossella Sorice Tim D Spector John M Starr Doris Stöckl Konstantin Strauch Michael Stumvoll Morris A Swertz Unnur Thorsteinsdottir A Roy Thurik Nicholas J Timpson Joyce Y Tung André G Uitterlinden Simona Vaccargiu Jorma Viikari Veronique Vitart Henry Völzke Peter Vollenweider Dragana Vuckovic Johannes Waage Gert G Wagner Jie Jin Wang Nicholas J Wareham David R Weir Gonneke Willemsen Johann Willeit Alan F Wright Krina T Zondervan Kari Stefansson Robert F Krueger James J Lee Daniel J Benjamin David Cesarini Philipp D Koellinger Marcel den Hoed Harold Snieder Melinda C Mills

Nat Genet 2016 12 31;48(12):1462-1472. Epub 2016 Oct 31.

Department of Sociology and Nuffield College, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1038/ng.3698DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5695684PMC
December 2016

Lower sex hormone levels are associated with more chronic musculoskeletal pain in community-dwelling elderly women.

Pain 2016 07;157(7):1425-31

Departments of aInternal MedicinebAnaesthesiologycClinical ChemistrydGeneral Practice, Erasmus MCeOrthopedic Surgery, University Medical Center Rotterdam, the NetherlandsfEpidemiology, Erasmus MC, Rotterdam, the Netherlands.

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http://dx.doi.org/10.1097/j.pain.0000000000000535DOI Listing
July 2016

Genome-wide association study in an admixed case series reveals IL12A as a new candidate in Behçet disease.

PLoS One 2015 23;10(3):e0119085. Epub 2015 Mar 23.

Internal medicine, Section immunology, Erasmus Medical Center, Rotterdam, The Netherlands; Department of Immunology, Erasmus Medical Center, Rotterdam, The Netherlands.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0119085PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4370488PMC
February 2016

Corrigendum: Rare coding variants and X-linked loci associated with age at menarche.

Nat Commun 2015 Dec 17;6:10257. Epub 2015 Dec 17.

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http://dx.doi.org/10.1038/ncomms10257DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4703878PMC
December 2015

Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation.

Authors:
Norihiro Kato Marie Loh Fumihiko Takeuchi Niek Verweij Xu Wang Weihua Zhang Tanika N Kelly Danish Saleheen Benjamin Lehne Irene Mateo Leach Alexander W Drong James Abbott Simone Wahl Sian-Tsung Tan William R Scott Gianluca Campanella Marc Chadeau-Hyam Uzma Afzal Tarunveer S Ahluwalia Marc Jan Bonder Peng Chen Abbas Dehghan Todd L Edwards Tõnu Esko Min Jin Go Sarah E Harris Jaana Hartiala Silva Kasela Anuradhani Kasturiratne Chiea-Chuen Khor Marcus E Kleber Huaixing Li Zuan Yu Mok Masahiro Nakatochi Nur Sabrina Sapari Richa Saxena Alexandre F R Stewart Lisette Stolk Yasuharu Tabara Ai Ling Teh Ying Wu Jer-Yuarn Wu Yi Zhang Imke Aits Alexessander Da Silva Couto Alves Shikta Das Rajkumar Dorajoo Jemma C Hopewell Yun Kyoung Kim Robert W Koivula Jian'an Luan Leo-Pekka Lyytikäinen Quang N Nguyen Mark A Pereira Iris Postmus Olli T Raitakari Molly Scannell Bryan Robert A Scott Rossella Sorice Vinicius Tragante Michela Traglia Jon White Ken Yamamoto Yonghong Zhang Linda S Adair Alauddin Ahmed Koichi Akiyama Rasheed Asif Tin Aung Inês Barroso Andrew Bjonnes Timothy R Braun Hui Cai Li-Ching Chang Chien-Hsiun Chen Ching-Yu Cheng Yap-Seng Chong Rory Collins Regina Courtney Gail Davies Graciela Delgado Loi D Do Pieter A Doevendans Ron T Gansevoort Yu-Tang Gao Tanja B Grammer Niels Grarup Jagvir Grewal Dongfeng Gu Gurpreet S Wander Anna-Liisa Hartikainen Stanley L Hazen Jing He Chew-Kiat Heng James E Hixson Albert Hofman Chris Hsu Wei Huang Lise L N Husemoen Joo-Yeon Hwang Sahoko Ichihara Michiya Igase Masato Isono Johanne M Justesen Tomohiro Katsuya Muhammad G Kibriya Young Jin Kim Miyako Kishimoto Woon-Puay Koh Katsuhiko Kohara Meena Kumari Kenneth Kwek Nanette R Lee Jeannette Lee Jiemin Liao Wolfgang Lieb David C M Liewald Tatsuaki Matsubara Yumi Matsushita Thomas Meitinger Evelin Mihailov Lili Milani Rebecca Mills Nina Mononen Martina Müller-Nurasyid Toru Nabika Eitaro Nakashima Hong Kiat Ng Kjell Nikus Teresa Nutile Takayoshi Ohkubo Keizo Ohnaka Sarah Parish Lavinia Paternoster Hao Peng Annette Peters Son T Pham Mohitha J Pinidiyapathirage Mahfuzar Rahman Hiromi Rakugi Olov Rolandsson Michelle Ann Rozario Daniela Ruggiero Cinzia F Sala Ralhan Sarju Kazuro Shimokawa Harold Snieder Thomas Sparsø Wilko Spiering John M Starr David J Stott Daniel O Stram Takao Sugiyama Silke Szymczak W H Wilson Tang Lin Tong Stella Trompet Väinö Turjanmaa Hirotsugu Ueshima André G Uitterlinden Satoshi Umemura Marja Vaarasmaki Rob M van Dam Wiek H van Gilst Dirk J van Veldhuisen Jorma S Viikari Melanie Waldenberger Yiqin Wang Aili Wang Rory Wilson Tien-Yin Wong Yong-Bing Xiang Shuhei Yamaguchi Xingwang Ye Robin D Young Terri L Young Jian-Min Yuan Xueya Zhou Folkert W Asselbergs Marina Ciullo Robert Clarke Panos Deloukas Andre Franke Paul W Franks Steve Franks Yechiel Friedlander Myron D Gross Zhirong Guo Torben Hansen Marjo-Riitta Jarvelin Torben Jørgensen J Wouter Jukema Mika Kähönen Hiroshi Kajio Mika Kivimaki Jong-Young Lee Terho Lehtimäki Allan Linneberg Tetsuro Miki Oluf Pedersen Nilesh J Samani Thorkild I A Sørensen Ryoichi Takayanagi Daniela Toniolo Habibul Ahsan Hooman Allayee Yuan-Tsong Chen John Danesh Ian J Deary Oscar H Franco Lude Franke Bastiaan T Heijman Joanna D Holbrook Aaron Isaacs Bong-Jo Kim Xu Lin Jianjun Liu Winfried März Andres Metspalu Karen L Mohlke Dharambir K Sanghera Xiao-Ou Shu Joyce B J van Meurs Eranga Vithana Ananda R Wickremasinghe Cisca Wijmenga Bruce H W Wolffenbuttel Mitsuhiro Yokota Wei Zheng Dingliang Zhu Paolo Vineis Soterios A Kyrtopoulos Jos C S Kleinjans Mark I McCarthy Richie Soong Christian Gieger James Scott Yik-Ying Teo Jiang He Paul Elliott E Shyong Tai Pim van der Harst Jaspal S Kooner John C Chambers

Nat Genet 2015 11 21;47(11):1282-1293. Epub 2015 Sep 21.

Department of Epidemiology and Biostatistics, Imperial College London, London, UK.

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November 2015

Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair.

Authors:
Felix R Day Katherine S Ruth Deborah J Thompson Kathryn L Lunetta Natalia Pervjakova Daniel I Chasman Lisette Stolk Hilary K Finucane Patrick Sulem Brendan Bulik-Sullivan Tõnu Esko Andrew D Johnson Cathy E Elks Nora Franceschini Chunyan He Elisabeth Altmaier Jennifer A Brody Lude L Franke Jennifer E Huffman Margaux F Keller Patrick F McArdle Teresa Nutile Eleonora Porcu Antonietta Robino Lynda M Rose Ursula M Schick Jennifer A Smith Alexander Teumer Michela Traglia Dragana Vuckovic Jie Yao Wei Zhao Eva Albrecht Najaf Amin Tanguy Corre Jouke-Jan Hottenga Massimo Mangino Albert V Smith Toshiko Tanaka Goncalo Abecasis Irene L Andrulis Hoda Anton-Culver Antonis C Antoniou Volker Arndt Alice M Arnold Caterina Barbieri Matthias W Beckmann Alicia Beeghly-Fadiel Javier Benitez Leslie Bernstein Suzette J Bielinski Carl Blomqvist Eric Boerwinkle Natalia V Bogdanova Stig E Bojesen Manjeet K Bolla Anne-Lise Borresen-Dale Thibaud S Boutin Hiltrud Brauch Hermann Brenner Thomas Brüning Barbara Burwinkel Archie Campbell Harry Campbell Stephen J Chanock J Ross Chapman Yii-Der Ida Chen Georgia Chenevix-Trench Fergus J Couch Andrea D Coviello Angela Cox Kamila Czene Hatef Darabi Immaculata De Vivo Ellen W Demerath Joe Dennis Peter Devilee Thilo Dörk Isabel Dos-Santos-Silva Alison M Dunning John D Eicher Peter A Fasching Jessica D Faul Jonine Figueroa Dieter Flesch-Janys Ilaria Gandin Melissa E Garcia Montserrat García-Closas Graham G Giles Giorgia G Girotto Mark S Goldberg Anna González-Neira Mark O Goodarzi Megan L Grove Daniel F Gudbjartsson Pascal Guénel Xiuqing Guo Christopher A Haiman Per Hall Ute Hamann Brian E Henderson Lynne J Hocking Albert Hofman Georg Homuth Maartje J Hooning John L Hopper Frank B Hu Jinyan Huang Keith Humphreys David J Hunter Anna Jakubowska Samuel E Jones Maria Kabisch David Karasik Julia A Knight Ivana Kolcic Charles Kooperberg Veli-Matti Kosma Jennifer Kriebel Vessela Kristensen Diether Lambrechts Claudia Langenberg Jingmei Li Xin Li Sara Lindström Yongmei Liu Jian'an Luan Jan Lubinski Reedik Mägi Arto Mannermaa Judith Manz Sara Margolin Jonathan Marten Nicholas G Martin Corrado Masciullo Alfons Meindl Kyriaki Michailidou Evelin Mihailov Lili Milani Roger L Milne Martina Müller-Nurasyid Michael Nalls Ben M Neale Heli Nevanlinna Patrick Neven Anne B Newman Børge G Nordestgaard Janet E Olson Sandosh Padmanabhan Paolo Peterlongo Ulrike Peters Astrid Petersmann Julian Peto Paul D P Pharoah Nicola N Pirastu Ailith Pirie Giorgio Pistis Ozren Polasek David Porteous Bruce M Psaty Katri Pylkäs Paolo Radice Leslie J Raffel Fernando Rivadeneira Igor Rudan Anja Rudolph Daniela Ruggiero Cinzia F Sala Serena Sanna Elinor J Sawyer David Schlessinger Marjanka K Schmidt Frank Schmidt Rita K Schmutzler Minouk J Schoemaker Robert A Scott Caroline M Seynaeve Jacques Simard Rossella Sorice Melissa C Southey Doris Stöckl Konstantin Strauch Anthony Swerdlow Kent D Taylor Unnur Thorsteinsdottir Amanda E Toland Ian Tomlinson Thérèse Truong Laufey Tryggvadottir Stephen T Turner Diego Vozzi Qin Wang Melissa Wellons Gonneke Willemsen James F Wilson Robert Winqvist Bruce B H R Wolffenbuttel Alan F Wright Drakoulis Yannoukakos Tatijana Zemunik Wei Zheng Marek Zygmunt Sven Bergmann Dorret I Boomsma Julie E Buring Luigi Ferrucci Grant W Montgomery Vilmundur Gudnason Tim D Spector Cornelia M van Duijn Behrooz Z Alizadeh Marina Ciullo Laura Crisponi Douglas F Easton Paolo P Gasparini Christian Gieger Tamara B Harris Caroline Hayward Sharon L R Kardia Peter Kraft Barbara McKnight Andres Metspalu Alanna C Morrison Alex P Reiner Paul M Ridker Jerome I Rotter Daniela Toniolo André G Uitterlinden Sheila Ulivi Henry Völzke Nicholas J Wareham David R Weir Laura M Yerges-Armstrong Alkes L Price Kari Stefansson Jenny A Visser Ken K Ong Jenny Chang-Claude Joanne M Murabito John R B Perry Anna Murray

Nat Genet 2015 Nov 28;47(11):1294-1303. Epub 2015 Sep 28.

Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, EX2 5DW, UK.

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November 2015

The transcriptional landscape of age in human peripheral blood.

Authors:
Marjolein J Peters Roby Joehanes Luke C Pilling Claudia Schurmann Karen N Conneely Joseph Powell Eva Reinmaa George L Sutphin Alexandra Zhernakova Katharina Schramm Yana A Wilson Sayuko Kobes Taru Tukiainen Yolande F Ramos Harald H H Göring Myriam Fornage Yongmei Liu Sina A Gharib Barbara E Stranger Philip L De Jager Abraham Aviv Daniel Levy Joanne M Murabito Peter J Munson Tianxiao Huan Albert Hofman André G Uitterlinden Fernando Rivadeneira Jeroen van Rooij Lisette Stolk Linda Broer Michael M P J Verbiest Mila Jhamai Pascal Arp Andres Metspalu Liina Tserel Lili Milani Nilesh J Samani Pärt Peterson Silva Kasela Veryan Codd Annette Peters Cavin K Ward-Caviness Christian Herder Melanie Waldenberger Michael Roden Paula Singmann Sonja Zeilinger Thomas Illig Georg Homuth Hans-Jörgen Grabe Henry Völzke Leif Steil Thomas Kocher Anna Murray David Melzer Hanieh Yaghootkar Stefania Bandinelli Eric K Moses Jack W Kent Joanne E Curran Matthew P Johnson Sarah Williams-Blangero Harm-Jan Westra Allan F McRae Jennifer A Smith Sharon L R Kardia Iiris Hovatta Markus Perola Samuli Ripatti Veikko Salomaa Anjali K Henders Nicholas G Martin Alicia K Smith Divya Mehta Elisabeth B Binder K Maria Nylocks Elizabeth M Kennedy Torsten Klengel Jingzhong Ding Astrid M Suchy-Dicey Daniel A Enquobahrie Jennifer Brody Jerome I Rotter Yii-Der I Chen Jeanine Houwing-Duistermaat Margreet Kloppenburg P Eline Slagboom Quinta Helmer Wouter den Hollander Shannon Bean Towfique Raj Noman Bakhshi Qiao Ping Wang Lisa J Oyston Bruce M Psaty Russell P Tracy Grant W Montgomery Stephen T Turner John Blangero Ingrid Meulenbelt Kerry J Ressler Jian Yang Lude Franke Johannes Kettunen Peter M Visscher G Gregory Neely Ron Korstanje Robert L Hanson Holger Prokisch Luigi Ferrucci Tonu Esko Alexander Teumer Joyce B J van Meurs Andrew D Johnson

Nat Commun 2015 Oct 22;6:8570. Epub 2015 Oct 22.

The National Heart, Lung, and Blood Institute's and Boston University's Framingham Heart Study, Framingham, Massachusetts 01702, USA.

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October 2015

Rare coding variants and X-linked loci associated with age at menarche.

Nat Commun 2015 Aug 4;6:7756. Epub 2015 Aug 4.

MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Box 285 Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK.

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August 2015

Tobacco smoking is associated with methylation of genes related to coronary artery disease.

Clin Epigenetics 2015 14;7:54. Epub 2015 May 14.

Department of Epidemiology, Erasmus University Medical Centre, 's Gravendijkwal 230, 3015 CE Rotterdam, The Netherlands.

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May 2015

New genetic loci link adipose and insulin biology to body fat distribution.

Authors:
Dmitry Shungin Thomas W Winkler Damien C Croteau-Chonka Teresa Ferreira Adam E Locke Reedik Mägi Rona J Strawbridge Tune H Pers Krista Fischer Anne E Justice Tsegaselassie Workalemahu Joseph M W Wu Martin L Buchkovich Nancy L Heard-Costa Tamara S Roman Alexander W Drong Ci Song Stefan Gustafsson Felix R Day Tonu Esko Tove Fall Zoltán Kutalik Jian'an Luan Joshua C Randall André Scherag Sailaja Vedantam Andrew R Wood Jin Chen Rudolf Fehrmann Juha Karjalainen Bratati Kahali Ching-Ti Liu Ellen M Schmidt Devin Absher Najaf Amin Denise Anderson Marian Beekman Jennifer L Bragg-Gresham Steven Buyske Ayse Demirkan Georg B Ehret Mary F Feitosa Anuj Goel Anne U Jackson Toby Johnson Marcus E Kleber Kati Kristiansson Massimo Mangino Irene Mateo Leach Carolina Medina-Gomez Cameron D Palmer Dorota Pasko Sonali Pechlivanis Marjolein J Peters Inga Prokopenko Alena Stančáková Yun Ju Sung Toshiko Tanaka Alexander Teumer Jana V Van Vliet-Ostaptchouk Loïc Yengo Weihua Zhang Eva Albrecht Johan Ärnlöv Gillian M Arscott Stefania Bandinelli Amy Barrett Claire Bellis Amanda J Bennett Christian Berne Matthias Blüher Stefan Böhringer Fabrice Bonnet Yvonne Böttcher Marcel Bruinenberg Delia B Carba Ida H Caspersen Robert Clarke E Warwick Daw Joris Deelen Ewa Deelman Graciela Delgado Alex Sf Doney Niina Eklund Michael R Erdos Karol Estrada Elodie Eury Nele Friedrich Melissa E Garcia Vilmantas Giedraitis Bruna Gigante Alan S Go Alain Golay Harald Grallert Tanja B Grammer Jürgen Gräßler Jagvir Grewal Christopher J Groves Toomas Haller Goran Hallmans Catharina A Hartman Maija Hassinen Caroline Hayward Kauko Heikkilä Karl-Heinz Herzig Quinta Helmer Hans L Hillege Oddgeir Holmen Steven C Hunt Aaron Isaacs Till Ittermann Alan L James Ingegerd Johansson Thorhildur Juliusdottir Ioanna-Panagiota Kalafati Leena Kinnunen Wolfgang Koenig Ishminder K Kooner Wolfgang Kratzer Claudia Lamina Karin Leander Nanette R Lee Peter Lichtner Lars Lind Jaana Lindström Stéphane Lobbens Mattias Lorentzon François Mach Patrik Ke Magnusson Anubha Mahajan Wendy L McArdle Cristina Menni Sigrun Merger Evelin Mihailov Lili Milani Rebecca Mills Alireza Moayyeri Keri L Monda Simon P Mooijaart Thomas W Mühleisen Antonella Mulas Gabriele Müller Martina Müller-Nurasyid Ramaiah Nagaraja Michael A Nalls Narisu Narisu Nicola Glorioso Ilja M Nolte Matthias Olden Nigel W Rayner Frida Renstrom Janina S Ried Neil R Robertson Lynda M Rose Serena Sanna Hubert Scharnagl Salome Scholtens Bengt Sennblad Thomas Seufferlein Colleen M Sitlani Albert Vernon Smith Kathleen Stirrups Heather M Stringham Johan Sundström Morris A Swertz Amy J Swift Ann-Christine Syvänen Bamidele O Tayo Barbara Thorand Gudmar Thorleifsson Andreas Tomaschitz Chiara Troffa Floor Va van Oort Niek Verweij Judith M Vonk Lindsay L Waite Roman Wennauer Tom Wilsgaard Mary K Wojczynski Andrew Wong Qunyuan Zhang Jing Hua Zhao Eoin P Brennan Murim Choi Per Eriksson Lasse Folkersen Anders Franco-Cereceda Ali G Gharavi Åsa K Hedman Marie-France Hivert Jinyan Huang Stavroula Kanoni Fredrik Karpe Sarah Keildson Krzysztof Kiryluk Liming Liang Richard P Lifton Baoshan Ma Amy J McKnight Ruth McPherson Andres Metspalu Josine L Min Miriam F Moffatt Grant W Montgomery Joanne M Murabito George Nicholson Dale R Nyholt Christian Olsson John Rb Perry Eva Reinmaa Rany M Salem Niina Sandholm Eric E Schadt Robert A Scott Lisette Stolk Edgar E Vallejo Harm-Jan Westra Krina T Zondervan Philippe Amouyel Dominique Arveiler Stephan Jl Bakker John Beilby Richard N Bergman John Blangero Morris J Brown Michel Burnier Harry Campbell Aravinda Chakravarti Peter S Chines Simone Claudi-Boehm Francis S Collins Dana C Crawford John Danesh Ulf de Faire Eco Jc de Geus Marcus Dörr Raimund Erbel Johan G Eriksson Martin Farrall Ele Ferrannini Jean Ferrières Nita G Forouhi Terrence Forrester Oscar H Franco Ron T Gansevoort Christian Gieger Vilmundur Gudnason Christopher A Haiman Tamara B Harris Andrew T Hattersley Markku Heliövaara Andrew A Hicks Aroon D Hingorani Wolfgang Hoffmann Albert Hofman Georg Homuth Steve E Humphries Elina Hyppönen Thomas Illig Marjo-Riitta Jarvelin Berit Johansen Pekka Jousilahti Antti M Jula Jaakko Kaprio Frank Kee Sirkka M Keinanen-Kiukaanniemi Jaspal S Kooner Charles Kooperberg Peter Kovacs Aldi T Kraja Meena Kumari Kari Kuulasmaa Johanna Kuusisto Timo A Lakka Claudia Langenberg Loic Le Marchand Terho Lehtimäki Valeriya Lyssenko Satu Männistö André Marette Tara C Matise Colin A McKenzie Barbara McKnight Arthur W Musk Stefan Möhlenkamp Andrew D Morris Mari Nelis Claes Ohlsson Albertine J Oldehinkel Ken K Ong Lyle J Palmer Brenda W Penninx Annette Peters Peter P Pramstaller Olli T Raitakari Tuomo Rankinen D C Rao Treva K Rice Paul M Ridker Marylyn D Ritchie Igor Rudan Veikko Salomaa Nilesh J Samani Jouko Saramies Mark A Sarzynski Peter Eh Schwarz Alan R Shuldiner Jan A Staessen Valgerdur Steinthorsdottir Ronald P Stolk Konstantin Strauch Anke Tönjes Angelo Tremblay Elena Tremoli Marie-Claude Vohl Uwe Völker Peter Vollenweider James F Wilson Jacqueline C Witteman Linda S Adair Murielle Bochud Bernhard O Boehm Stefan R Bornstein Claude Bouchard Stéphane Cauchi Mark J Caulfield John C Chambers Daniel I Chasman Richard S Cooper George Dedoussis Luigi Ferrucci Philippe Froguel Hans-Jörgen Grabe Anders Hamsten Jennie Hui Kristian Hveem Karl-Heinz Jöckel Mika Kivimaki Diana Kuh Markku Laakso Yongmei Liu Winfried März Patricia B Munroe Inger Njølstad Ben A Oostra Colin Na Palmer Nancy L Pedersen Markus Perola Louis Pérusse Ulrike Peters Chris Power Thomas Quertermous Rainer Rauramaa Fernando Rivadeneira Timo E Saaristo Danish Saleheen Juha Sinisalo P Eline Slagboom Harold Snieder Tim D Spector Kari Stefansson Michael Stumvoll Jaakko Tuomilehto André G Uitterlinden Matti Uusitupa Pim van der Harst Giovanni Veronesi Mark Walker Nicholas J Wareham Hugh Watkins H-Erich Wichmann Goncalo R Abecasis Themistocles L Assimes Sonja I Berndt Michael Boehnke Ingrid B Borecki Panos Deloukas Lude Franke Timothy M Frayling Leif C Groop David J Hunter Robert C Kaplan Jeffrey R O'Connell Lu Qi David Schlessinger David P Strachan Unnur Thorsteinsdottir Cornelia M van Duijn Cristen J Willer Peter M Visscher Jian Yang Joel N Hirschhorn M Carola Zillikens Mark I McCarthy Elizabeth K Speliotes Kari E North Caroline S Fox Inês Barroso Paul W Franks Erik Ingelsson Iris M Heid Ruth Jf Loos L Adrienne Cupples Andrew P Morris Cecilia M Lindgren Karen L Mohlke

Nature 2015 Feb;518(7538):187-196

Department of Genetics, University of North Carolina, Chapel Hill, NC 27599, USA.

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February 2015

Genetic studies of body mass index yield new insights for obesity biology.

Authors:
Adam E Locke Bratati Kahali Sonja I Berndt Anne E Justice Tune H Pers Felix R Day Corey Powell Sailaja Vedantam Martin L Buchkovich Jian Yang Damien C Croteau-Chonka Tonu Esko Tove Fall Teresa Ferreira Stefan Gustafsson Zoltán Kutalik Jian'an Luan Reedik Mägi Joshua C Randall Thomas W Winkler Andrew R Wood Tsegaselassie Workalemahu Jessica D Faul Jennifer A Smith Jing Hua Zhao Wei Zhao Jin Chen Rudolf Fehrmann Åsa K Hedman Juha Karjalainen Ellen M Schmidt Devin Absher Najaf Amin Denise Anderson Marian Beekman Jennifer L Bolton Jennifer L Bragg-Gresham Steven Buyske Ayse Demirkan Guohong Deng Georg B Ehret Bjarke Feenstra Mary F Feitosa Krista Fischer Anuj Goel Jian Gong Anne U Jackson Stavroula Kanoni Marcus E Kleber Kati Kristiansson Unhee Lim Vaneet Lotay Massimo Mangino Irene Mateo Leach Carolina Medina-Gomez Sarah E Medland Michael A Nalls Cameron D Palmer Dorota Pasko Sonali Pechlivanis Marjolein J Peters Inga Prokopenko Dmitry Shungin Alena Stančáková Rona J Strawbridge Yun Ju Sung Toshiko Tanaka Alexander Teumer Stella Trompet Sander W van der Laan Jessica van Setten Jana V Van Vliet-Ostaptchouk Zhaoming Wang Loïc Yengo Weihua Zhang Aaron Isaacs Eva Albrecht Johan Ärnlöv Gillian M Arscott Antony P Attwood Stefania Bandinelli Amy Barrett Isabelita N Bas Claire Bellis Amanda J Bennett Christian Berne Roza Blagieva Matthias Blüher Stefan Böhringer Lori L Bonnycastle Yvonne Böttcher Heather A Boyd Marcel Bruinenberg Ida H Caspersen Yii-Der Ida Chen Robert Clarke E Warwick Daw Anton J M de Craen Graciela Delgado Maria Dimitriou Alex S F Doney Niina Eklund Karol Estrada Elodie Eury Lasse Folkersen Ross M Fraser Melissa E Garcia Frank Geller Vilmantas Giedraitis Bruna Gigante Alan S Go Alain Golay Alison H Goodall Scott D Gordon Mathias Gorski Hans-Jörgen Grabe Harald Grallert Tanja B Grammer Jürgen Gräßler Henrik Grönberg Christopher J Groves Gaëlle Gusto Jeffrey Haessler Per Hall Toomas Haller Goran Hallmans Catharina A Hartman Maija Hassinen Caroline Hayward Nancy L Heard-Costa Quinta Helmer Christian Hengstenberg Oddgeir Holmen Jouke-Jan Hottenga Alan L James Janina M Jeff Åsa Johansson Jennifer Jolley Thorhildur Juliusdottir Leena Kinnunen Wolfgang Koenig Markku Koskenvuo Wolfgang Kratzer Jaana Laitinen Claudia Lamina Karin Leander Nanette R Lee Peter Lichtner Lars Lind Jaana Lindström Ken Sin Lo Stéphane Lobbens Roberto Lorbeer Yingchang Lu François Mach Patrik K E Magnusson Anubha Mahajan Wendy L McArdle Stela McLachlan Cristina Menni Sigrun Merger Evelin Mihailov Lili Milani Alireza Moayyeri Keri L Monda Mario A Morken Antonella Mulas Gabriele Müller Martina Müller-Nurasyid Arthur W Musk Ramaiah Nagaraja Markus M Nöthen Ilja M Nolte Stefan Pilz Nigel W Rayner Frida Renstrom Rainer Rettig Janina S Ried Stephan Ripke Neil R Robertson Lynda M Rose Serena Sanna Hubert Scharnagl Salome Scholtens Fredrick R Schumacher William R Scott Thomas Seufferlein Jianxin Shi Albert Vernon Smith Joanna Smolonska Alice V Stanton Valgerdur Steinthorsdottir Kathleen Stirrups Heather M Stringham Johan Sundström Morris A Swertz Amy J Swift Ann-Christine Syvänen Sian-Tsung Tan Bamidele O Tayo Barbara Thorand Gudmar Thorleifsson Jonathan P Tyrer Hae-Won Uh Liesbeth Vandenput Frank C Verhulst Sita H Vermeulen Niek Verweij Judith M Vonk Lindsay L Waite Helen R Warren Dawn Waterworth Michael N Weedon Lynne R Wilkens Christina Willenborg Tom Wilsgaard Mary K Wojczynski Andrew Wong Alan F Wright Qunyuan Zhang Eoin P Brennan Murim Choi Zari Dastani Alexander W Drong Per Eriksson Anders Franco-Cereceda Jesper R Gådin Ali G Gharavi Michael E Goddard Robert E Handsaker Jinyan Huang Fredrik Karpe Sekar Kathiresan Sarah Keildson Krzysztof Kiryluk Michiaki Kubo Jong-Young Lee Liming Liang Richard P Lifton Baoshan Ma Steven A McCarroll Amy J McKnight Josine L Min Miriam F Moffatt Grant W Montgomery Joanne M Murabito George Nicholson Dale R Nyholt Yukinori Okada John R B Perry Rajkumar Dorajoo Eva Reinmaa Rany M Salem Niina Sandholm Robert A Scott Lisette Stolk Atsushi Takahashi Toshihiro Tanaka Ferdinand M van 't Hooft Anna A E Vinkhuyzen Harm-Jan Westra Wei Zheng Krina T Zondervan Andrew C Heath Dominique Arveiler Stephan J L Bakker John Beilby Richard N Bergman John Blangero Pascal Bovet Harry Campbell Mark J Caulfield Giancarlo Cesana Aravinda Chakravarti Daniel I Chasman Peter S Chines Francis S Collins Dana C Crawford L Adrienne Cupples Daniele Cusi John Danesh Ulf de Faire Hester M den Ruijter Anna F Dominiczak Raimund Erbel Jeanette Erdmann Johan G Eriksson Martin Farrall Stephan B Felix Ele Ferrannini Jean Ferrières Ian Ford Nita G Forouhi Terrence Forrester Oscar H Franco Ron T Gansevoort Pablo V Gejman Christian Gieger Omri Gottesman Vilmundur Gudnason Ulf Gyllensten Alistair S Hall Tamara B Harris Andrew T Hattersley Andrew A Hicks Lucia A Hindorff Aroon D Hingorani Albert Hofman Georg Homuth G Kees Hovingh Steve E Humphries Steven C Hunt Elina Hyppönen Thomas Illig Kevin B Jacobs Marjo-Riitta Jarvelin Karl-Heinz Jöckel Berit Johansen Pekka Jousilahti J Wouter Jukema Antti M Jula Jaakko Kaprio John J P Kastelein Sirkka M Keinanen-Kiukaanniemi Lambertus A Kiemeney Paul Knekt Jaspal S Kooner Charles Kooperberg Peter Kovacs Aldi T Kraja Meena Kumari Johanna Kuusisto Timo A Lakka Claudia Langenberg Loic Le Marchand Terho Lehtimäki Valeriya Lyssenko Satu Männistö André Marette Tara C Matise Colin A McKenzie Barbara McKnight Frans L Moll Andrew D Morris Andrew P Morris Jeffrey C Murray Mari Nelis Claes Ohlsson Albertine J Oldehinkel Ken K Ong Pamela A F Madden Gerard Pasterkamp John F Peden Annette Peters Dirkje S Postma Peter P Pramstaller Jackie F Price Lu Qi Olli T Raitakari Tuomo Rankinen D C Rao Treva K Rice Paul M Ridker John D Rioux Marylyn D Ritchie Igor Rudan Veikko Salomaa Nilesh J Samani Jouko Saramies Mark A Sarzynski Heribert Schunkert Peter E H Schwarz Peter Sever Alan R Shuldiner Juha Sinisalo Ronald P Stolk Konstantin Strauch Anke Tönjes David-Alexandre Trégouët Angelo Tremblay Elena Tremoli Jarmo Virtamo Marie-Claude Vohl Uwe Völker Gérard Waeber Gonneke Willemsen Jacqueline C Witteman M Carola Zillikens Linda S Adair Philippe Amouyel Folkert W Asselbergs Themistocles L Assimes Murielle Bochud Bernhard O Boehm Eric Boerwinkle Stefan R Bornstein Erwin P Bottinger Claude Bouchard Stéphane Cauchi John C Chambers Stephen J Chanock Richard S Cooper Paul I W de Bakker George Dedoussis Luigi Ferrucci Paul W Franks Philippe Froguel Leif C Groop Christopher A Haiman Anders Hamsten Jennie Hui David J Hunter Kristian Hveem Robert C Kaplan Mika Kivimaki Diana Kuh Markku Laakso Yongmei Liu Nicholas G Martin Winfried März Mads Melbye Andres Metspalu Susanne Moebus Patricia B Munroe Inger Njølstad Ben A Oostra Colin N A Palmer Nancy L Pedersen Markus Perola Louis Pérusse Ulrike Peters Chris Power Thomas Quertermous Rainer Rauramaa Fernando Rivadeneira Timo E Saaristo Danish Saleheen Naveed Sattar Eric E Schadt David Schlessinger P Eline Slagboom Harold Snieder Tim D Spector Unnur Thorsteinsdottir Michael Stumvoll Jaakko Tuomilehto André G Uitterlinden Matti Uusitupa Pim van der Harst Mark Walker Henri Wallaschofski Nicholas J Wareham Hugh Watkins David R Weir H-Erich Wichmann James F Wilson Pieter Zanen Ingrid B Borecki Panos Deloukas Caroline S Fox Iris M Heid Jeffrey R O'Connell David P Strachan Kari Stefansson Cornelia M van Duijn Gonçalo R Abecasis Lude Franke Timothy M Frayling Mark I McCarthy Peter M Visscher André Scherag Cristen J Willer Michael Boehnke Karen L Mohlke Cecilia M Lindgren Jacques S Beckmann Inês Barroso Kari E North Erik Ingelsson Joel N Hirschhorn Ruth J F Loos Elizabeth K Speliotes

Nature 2015 Feb;518(7538):197-206

Department of Internal Medicine, Division of Gastroenterology, and Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan 48109, USA.

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http://dx.doi.org/10.1038/nature14177DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4382211PMC
February 2015

Determinants of maternal pregnancy one-carbon metabolism and newborn human DNA methylation profiles.

Reproduction 2014 Dec;148(6):581-92

The Generation R Study GroupDepartment of Child and Adolescent PsychiatryDepartment of Obstetrics and GynecologyDepartment of Internal MedicineDepartment of EpidemiologyDepartment of PaediatricsDepartment of BiostatisticsDepartment of PsychiatryErasmus MC, University Medical Centre Rotterdam, Dr Molewaterplein 50, 3015 GE Rotterdam, The Netherlands

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http://dx.doi.org/10.1530/REP-14-0260DOI Listing
December 2014

Homocysteine and DNA methylation: a review of animal and human literature.

Mol Genet Metab 2014 Dec 14;113(4):243-52. Epub 2014 Oct 14.

Department of Clinical Chemistry, Erasmus University Medical Center, Rotterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.ymgme.2014.10.006DOI Listing
December 2014

BMI-associated alleles do not constitute risk alleles for polycystic ovary syndrome independently of BMI: a case-control study.

PLoS One 2014 31;9(1):e87335. Epub 2014 Jan 31.

Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom ; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, United Kingdom.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909077PMC
October 2014

Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche.

Authors:
John Rb Perry Felix Day Cathy E Elks Patrick Sulem Deborah J Thompson Teresa Ferreira Chunyan He Daniel I Chasman Tõnu Esko Gudmar Thorleifsson Eva Albrecht Wei Q Ang Tanguy Corre Diana L Cousminer Bjarke Feenstra Nora Franceschini Andrea Ganna Andrew D Johnson Sanela Kjellqvist Kathryn L Lunetta George McMahon Ilja M Nolte Lavinia Paternoster Eleonora Porcu Albert V Smith Lisette Stolk Alexander Teumer Natalia Tšernikova Emmi Tikkanen Sheila Ulivi Erin K Wagner Najaf Amin Laura J Bierut Enda M Byrne Jouke-Jan Hottenga Daniel L Koller Massimo Mangino Tune H Pers Laura M Yerges-Armstrong Jing Hua Zhao Irene L Andrulis Hoda Anton-Culver Femke Atsma Stefania Bandinelli Matthias W Beckmann Javier Benitez Carl Blomqvist Stig E Bojesen Manjeet K Bolla Bernardo Bonanni Hiltrud Brauch Hermann Brenner Julie E Buring Jenny Chang-Claude Stephen Chanock Jinhui Chen Georgia Chenevix-Trench J Margriet Collée Fergus J Couch David Couper Andrea D Coveillo Angela Cox Kamila Czene Adamo Pio D'adamo George Davey Smith Immaculata De Vivo Ellen W Demerath Joe Dennis Peter Devilee Aida K Dieffenbach Alison M Dunning Gudny Eiriksdottir Johan G Eriksson Peter A Fasching Luigi Ferrucci Dieter Flesch-Janys Henrik Flyger Tatiana Foroud Lude Franke Melissa E Garcia Montserrat García-Closas Frank Geller Eco Ej de Geus Graham G Giles Daniel F Gudbjartsson Vilmundur Gudnason Pascal Guénel Suiqun Guo Per Hall Ute Hamann Robin Haring Catharina A Hartman Andrew C Heath Albert Hofman Maartje J Hooning John L Hopper Frank B Hu David J Hunter David Karasik Douglas P Kiel Julia A Knight Veli-Matti Kosma Zoltan Kutalik Sandra Lai Diether Lambrechts Annika Lindblom Reedik Mägi Patrik K Magnusson Arto Mannermaa Nicholas G Martin Gisli Masson Patrick F McArdle Wendy L McArdle Mads Melbye Kyriaki Michailidou Evelin Mihailov Lili Milani Roger L Milne Heli Nevanlinna Patrick Neven Ellen A Nohr Albertine J Oldehinkel Ben A Oostra Aarno Palotie Munro Peacock Nancy L Pedersen Paolo Peterlongo Julian Peto Paul Dp Pharoah Dirkje S Postma Anneli Pouta Katri Pylkäs Paolo Radice Susan Ring Fernando Rivadeneira Antonietta Robino Lynda M Rose Anja Rudolph Veikko Salomaa Serena Sanna David Schlessinger Marjanka K Schmidt Mellissa C Southey Ulla Sovio Meir J Stampfer Doris Stöckl Anna M Storniolo Nicholas J Timpson Jonathan Tyrer Jenny A Visser Peter Vollenweider Henry Völzke Gerard Waeber Melanie Waldenberger Henri Wallaschofski Qin Wang Gonneke Willemsen Robert Winqvist Bruce Hr Wolffenbuttel Margaret J Wright Dorret I Boomsma Michael J Econs Kay-Tee Khaw Ruth Jf Loos Mark I McCarthy Grant W Montgomery John P Rice Elizabeth A Streeten Unnur Thorsteinsdottir Cornelia M van Duijn Behrooz Z Alizadeh Sven Bergmann Eric Boerwinkle Heather A Boyd Laura Crisponi Paolo Gasparini Christian Gieger Tamara B Harris Erik Ingelsson Marjo-Riitta Järvelin Peter Kraft Debbie Lawlor Andres Metspalu Craig E Pennell Paul M Ridker Harold Snieder Thorkild Ia Sørensen Tim D Spector David P Strachan André G Uitterlinden Nicholas J Wareham Elisabeth Widen Marek Zygmunt Anna Murray Douglas F Easton Kari Stefansson Joanne M Murabito Ken K Ong

Nature 2014 Oct 23;514(7520):92-97. Epub 2014 Jul 23.

MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Box 285 Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, CB2 0QQ, UK.

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http://dx.doi.org/10.1038/nature13545DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4185210PMC
October 2014

DNA methylation of IGF2DMR and H19 is associated with fetal and infant growth: the generation R study.

PLoS One 2013 12;8(12):e81731. Epub 2013 Dec 12.

Department of Obstetrics and Gynecology, Erasmus Medical Centre, Rotterdam, The Netherlands ; Department of Clinical Genetics, Erasmus Medical Centre, Rotterdam, The Netherlands.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3861253PMC
September 2014

DNA methylation profiles at birth and child ADHD symptoms.

J Psychiatr Res 2014 Feb 7;49:51-9. Epub 2013 Nov 7.

Department of Child and Adolescent Psychiatry, Erasmus MC, University Medical Center Rotterdam, Dr. Molewaterplein 50, 3015 GE Rotterdam, The Netherlands; Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Dr. Molewaterplein 50, 3015 GE Rotterdam, The Netherlands; Department of Psychiatry, Erasmus MC, University Medical Center Rotterdam, Dr. Molewaterplein 50, 3015 GE Rotterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.jpsychires.2013.10.017DOI Listing
February 2014

Cross-ethnic meta-analysis of genetic variants for polycystic ovary syndrome.

J Clin Endocrinol Metab 2013 Dec 8;98(12):E2006-12. Epub 2013 Oct 8.

MD, Department of Gynecology and Obstetrics, Room Na-1524, Erasmus MC, P.O. Box 2040, 3000 CA Rotterdam, The Netherlands.

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http://dx.doi.org/10.1210/jc.2013-2495DOI Listing
December 2013

Variants in SULT2A1 affect the DHEA sulphate to DHEA ratio in patients with polycystic ovary syndrome but not the hyperandrogenic phenotype.

J Clin Endocrinol Metab 2013 Sep 16;98(9):3848-55. Epub 2013 Jul 16.

Division of Reproductive Medicine, Department of Obstetrics and Gynecology, Erasmus University Medical Center, 3000 CA Rotterdam, The Netherlands.

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http://dx.doi.org/10.1210/jc.2013-1976DOI Listing
September 2013

Association of adiposity genetic variants with menarche timing in 92,105 women of European descent.

Am J Epidemiol 2013 Aug 4;178(3):451-60. Epub 2013 Apr 4.

Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, 137 East Franklin Street, Suite 306, Campus Box 8050, Chapel Hill, NC 27514-8050, USA.

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http://dx.doi.org/10.1093/aje/kws473DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3816344PMC
August 2013

Tissue-specific DNA methylation profiles in newborns.

Clin Epigenetics 2013 May 31;5(1). Epub 2013 May 31.

Department of Obstetrics and Gynaecology, Erasmus MC, University Medical Centre Rotterdam, dr, Molewaterplein 50, Rotterdam, GE 3015, the Netherlands.

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http://dx.doi.org/10.1186/1868-7083-5-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3684550PMC
May 2013

A genome-wide association meta-analysis of circulating sex hormone-binding globulin reveals multiple Loci implicated in sex steroid hormone regulation.

Authors:
Andrea D Coviello Robin Haring Melissa Wellons Dhananjay Vaidya Terho Lehtimäki Sarah Keildson Kathryn L Lunetta Chunyan He Myriam Fornage Vasiliki Lagou Massimo Mangino N Charlotte Onland-Moret Brian Chen Joel Eriksson Melissa Garcia Yong Mei Liu Annemarie Koster Kurt Lohman Leo-Pekka Lyytikäinen Ann-Kristin Petersen Jennifer Prescott Lisette Stolk Liesbeth Vandenput Andrew R Wood Wei Vivian Zhuang Aimo Ruokonen Anna-Liisa Hartikainen Anneli Pouta Stefania Bandinelli Reiner Biffar Georg Brabant David G Cox Yuhui Chen Steven Cummings Luigi Ferrucci Marc J Gunter Susan E Hankinson Hannu Martikainen Albert Hofman Georg Homuth Thomas Illig John-Olov Jansson Andrew D Johnson David Karasik Magnus Karlsson Johannes Kettunen Douglas P Kiel Peter Kraft Jingmin Liu Östen Ljunggren Mattias Lorentzon Marcello Maggio Marcello R P Markus Dan Mellström Iva Miljkovic Daniel Mirel Sarah Nelson Laure Morin Papunen Petra H M Peeters Inga Prokopenko Leslie Raffel Martin Reincke Alex P Reiner Kathryn Rexrode Fernando Rivadeneira Stephen M Schwartz David Siscovick Nicole Soranzo Doris Stöckl Shelley Tworoger André G Uitterlinden Carla H van Gils Ramachandran S Vasan H-Erich Wichmann Guangju Zhai Shalender Bhasin Martin Bidlingmaier Stephen J Chanock Immaculata De Vivo Tamara B Harris David J Hunter Mika Kähönen Simin Liu Pamela Ouyang Tim D Spector Yvonne T van der Schouw Jorma Viikari Henri Wallaschofski Mark I McCarthy Timothy M Frayling Anna Murray Steve Franks Marjo-Riitta Järvelin Frank H de Jong Olli Raitakari Alexander Teumer Claes Ohlsson Joanne M Murabito John R B Perry

PLoS Genet 2012 19;8(7):e1002805. Epub 2012 Jul 19.

Section of Preventive Medicine and Epidemiology, Boston University School of Medicine, Boston, Massachusetts, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1002805DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3400553PMC
January 2013

Genome-wide meta-analysis of common variant differences between men and women.

Authors:
Vesna Boraska Ana Jerončić Vincenza Colonna Lorraine Southam Dale R Nyholt Nigel William Rayner John R B Perry Daniela Toniolo Eva Albrecht Wei Ang Stefania Bandinelli Maja Barbalic Inês Barroso Jacques S Beckmann Reiner Biffar Dorret Boomsma Harry Campbell Tanguy Corre Jeanette Erdmann Tõnu Esko Krista Fischer Nora Franceschini Timothy M Frayling Giorgia Girotto Juan R Gonzalez Tamara B Harris Andrew C Heath Iris M Heid Wolfgang Hoffmann Albert Hofman Momoko Horikoshi Jing Hua Zhao Anne U Jackson Jouke-Jan Hottenga Antti Jula Mika Kähönen Kay-Tee Khaw Lambertus A Kiemeney Norman Klopp Zoltán Kutalik Vasiliki Lagou Lenore J Launer Terho Lehtimäki Mathieu Lemire Marja-Liisa Lokki Christina Loley Jian'an Luan Massimo Mangino Irene Mateo Leach Sarah E Medland Evelin Mihailov Grant W Montgomery Gerjan Navis John Newnham Markku S Nieminen Aarno Palotie Kalliope Panoutsopoulou Annette Peters Nicola Pirastu Ozren Polasek Karola Rehnström Samuli Ripatti Graham R S Ritchie Fernando Rivadeneira Antonietta Robino Nilesh J Samani So-Youn Shin Juha Sinisalo Johannes H Smit Nicole Soranzo Lisette Stolk Dorine W Swinkels Toshiko Tanaka Alexander Teumer Anke Tönjes Michela Traglia Jaakko Tuomilehto Armand Valsesia Wiek H van Gilst Joyce B J van Meurs Albert Vernon Smith Jorma Viikari Jacqueline M Vink Gerard Waeber Nicole M Warrington Elisabeth Widen Gonneke Willemsen Alan F Wright Brent W Zanke Lina Zgaga Michael Boehnke Adamo Pio d'Adamo Eco de Geus Ellen W Demerath Martin den Heijer Johan G Eriksson Luigi Ferrucci Christian Gieger Vilmundur Gudnason Caroline Hayward Christian Hengstenberg Thomas J Hudson Marjo-Riitta Järvelin Manolis Kogevinas Ruth J F Loos Nicholas G Martin Andres Metspalu Craig E Pennell Brenda W Penninx Markus Perola Olli Raitakari Veikko Salomaa Stefan Schreiber Heribert Schunkert Tim D Spector Michael Stumvoll André G Uitterlinden Sheila Ulivi Pim van der Harst Peter Vollenweider Henry Völzke Nicholas J Wareham H-Erich Wichmann James F Wilson Igor Rudan Yali Xue Eleftheria Zeggini

Hum Mol Genet 2012 Nov 27;21(21):4805-15. Epub 2012 Jul 27.

Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK.

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http://dx.doi.org/10.1093/hmg/dds304DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3471397PMC
November 2012

Mendelian randomization study of interleukin-6 in chronic obstructive pulmonary disease.

Respiration 2011 11;82(6):530-8. Epub 2011 Oct 11.

Department of Respiratory Medicine, Ghent University and Ghent University Hospital, Ghent, Belgium.

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http://dx.doi.org/10.1159/000332336DOI Listing
February 2012

Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways.

Authors:
Lisette Stolk John R B Perry Daniel I Chasman Chunyan He Massimo Mangino Patrick Sulem Maja Barbalic Linda Broer Enda M Byrne Florian Ernst Tõnu Esko Nora Franceschini Daniel F Gudbjartsson Jouke-Jan Hottenga Peter Kraft Patrick F McArdle Eleonora Porcu So-Youn Shin Albert V Smith Sophie van Wingerden Guangju Zhai Wei V Zhuang Eva Albrecht Behrooz Z Alizadeh Thor Aspelund Stefania Bandinelli Lovorka Barac Lauc Jacques S Beckmann Mladen Boban Eric Boerwinkle Frank J Broekmans Andrea Burri Harry Campbell Stephen J Chanock Constance Chen Marilyn C Cornelis Tanguy Corre Andrea D Coviello Pio d'Adamo Gail Davies Ulf de Faire Eco J C de Geus Ian J Deary George V Z Dedoussis Panagiotis Deloukas Shah Ebrahim Gudny Eiriksdottir Valur Emilsson Johan G Eriksson Bart C J M Fauser Liana Ferreli Luigi Ferrucci Krista Fischer Aaron R Folsom Melissa E Garcia Paolo Gasparini Christian Gieger Nicole Glazer Diederick E Grobbee Per Hall Toomas Haller Susan E Hankinson Merli Hass Caroline Hayward Andrew C Heath Albert Hofman Erik Ingelsson A Cecile J W Janssens Andrew D Johnson David Karasik Sharon L R Kardia Jules Keyzer Douglas P Kiel Ivana Kolcic Zoltán Kutalik Jari Lahti Sandra Lai Triin Laisk Joop S E Laven Debbie A Lawlor Jianjun Liu Lorna M Lopez Yvonne V Louwers Patrik K E Magnusson Mara Marongiu Nicholas G Martin Irena Martinovic Klaric Corrado Masciullo Barbara McKnight Sarah E Medland David Melzer Vincent Mooser Pau Navarro Anne B Newman Dale R Nyholt N Charlotte Onland-Moret Aarno Palotie Guillaume Paré Alex N Parker Nancy L Pedersen Petra H M Peeters Giorgio Pistis Andrew S Plump Ozren Polasek Victor J M Pop Bruce M Psaty Katri Räikkönen Emil Rehnberg Jerome I Rotter Igor Rudan Cinzia Sala Andres Salumets Angelo Scuteri Andrew Singleton Jennifer A Smith Harold Snieder Nicole Soranzo Simon N Stacey John M Starr Maria G Stathopoulou Kathleen Stirrups Ronald P Stolk Unnur Styrkarsdottir Yan V Sun Albert Tenesa Barbara Thorand Daniela Toniolo Laufey Tryggvadottir Kim Tsui Sheila Ulivi Rob M van Dam Yvonne T van der Schouw Carla H van Gils Peter van Nierop Jacqueline M Vink Peter M Visscher Marlies Voorhuis Gérard Waeber Henri Wallaschofski H Erich Wichmann Elisabeth Widen Colette J M Wijnands-van Gent Gonneke Willemsen James F Wilson Bruce H R Wolffenbuttel Alan F Wright Laura M Yerges-Armstrong Tatijana Zemunik Lina Zgaga M Carola Zillikens Marek Zygmunt Alice M Arnold Dorret I Boomsma Julie E Buring Laura Crisponi Ellen W Demerath Vilmundur Gudnason Tamara B Harris Frank B Hu David J Hunter Lenore J Launer Andres Metspalu Grant W Montgomery Ben A Oostra Paul M Ridker Serena Sanna David Schlessinger Tim D Spector Kari Stefansson Elizabeth A Streeten Unnur Thorsteinsdottir Manuela Uda André G Uitterlinden Cornelia M van Duijn Henry Völzke Anna Murray Joanne M Murabito Jenny A Visser Kathryn L Lunetta

Nat Genet 2012 Jan 22;44(3):260-8. Epub 2012 Jan 22.

Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1038/ng.1051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3288642PMC
January 2012

Genetic determinants of serum testosterone concentrations in men.

PLoS Genet 2011 Oct 6;7(10):e1002313. Epub 2011 Oct 6.

Center for Bone and Arthritis Research, Department of Internal Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Sweden.

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http://dx.plos.org/10.1371/journal.pgen.1002313
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3188559PMC
October 2011

Replication of association of a novel insulin receptor gene polymorphism with polycystic ovary syndrome.

Fertil Steril 2011 Apr;95(5):1736-41.e1-11

Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, California 90048, USA.

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http://dx.doi.org/10.1016/j.fertnstert.2011.01.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3062664PMC
April 2011

Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies.

Authors:
Cathy E Elks John R B Perry Patrick Sulem Daniel I Chasman Nora Franceschini Chunyan He Kathryn L Lunetta Jenny A Visser Enda M Byrne Diana L Cousminer Daniel F Gudbjartsson Tõnu Esko Bjarke Feenstra Jouke-Jan Hottenga Daniel L Koller Zoltán Kutalik Peng Lin Massimo Mangino Mara Marongiu Patrick F McArdle Albert V Smith Lisette Stolk Sophie H van Wingerden Jing Hua Zhao Eva Albrecht Tanguy Corre Erik Ingelsson Caroline Hayward Patrik K E Magnusson Erin N Smith Shelia Ulivi Nicole M Warrington Lina Zgaga Helen Alavere Najaf Amin Thor Aspelund Stefania Bandinelli Inês Barroso Gerald S Berenson Sven Bergmann Hannah Blackburn Eric Boerwinkle Julie E Buring Fabio Busonero Harry Campbell Stephen J Chanock Wei Chen Marilyn C Cornelis David Couper Andrea D Coviello Pio d'Adamo Ulf de Faire Eco J C de Geus Panos Deloukas Angela Döring George Davey Smith Douglas F Easton Gudny Eiriksdottir Valur Emilsson Johan Eriksson Luigi Ferrucci Aaron R Folsom Tatiana Foroud Melissa Garcia Paolo Gasparini Frank Geller Christian Gieger Vilmundur Gudnason Per Hall Susan E Hankinson Liana Ferreli Andrew C Heath Dena G Hernandez Albert Hofman Frank B Hu Thomas Illig Marjo-Riitta Järvelin Andrew D Johnson David Karasik Kay-Tee Khaw Douglas P Kiel Tuomas O Kilpeläinen Ivana Kolcic Peter Kraft Lenore J Launer Joop S E Laven Shengxu Li Jianjun Liu Daniel Levy Nicholas G Martin Wendy L McArdle Mads Melbye Vincent Mooser Jeffrey C Murray Sarah S Murray Michael A Nalls Pau Navarro Mari Nelis Andrew R Ness Kate Northstone Ben A Oostra Munro Peacock Lyle J Palmer Aarno Palotie Guillaume Paré Alex N Parker Nancy L Pedersen Leena Peltonen Craig E Pennell Paul Pharoah Ozren Polasek Andrew S Plump Anneli Pouta Eleonora Porcu Thorunn Rafnar John P Rice Susan M Ring Fernando Rivadeneira Igor Rudan Cinzia Sala Veikko Salomaa Serena Sanna David Schlessinger Nicholas J Schork Angelo Scuteri Ayellet V Segrè Alan R Shuldiner Nicole Soranzo Ulla Sovio Sathanur R Srinivasan David P Strachan Mar-Liis Tammesoo Emmi Tikkanen Daniela Toniolo Kim Tsui Laufey Tryggvadottir Jonathon Tyrer Manuela Uda Rob M van Dam Joyce B J van Meurs Peter Vollenweider Gerard Waeber Nicholas J Wareham Dawn M Waterworth Michael N Weedon H Erich Wichmann Gonneke Willemsen James F Wilson Alan F Wright Lauren Young Guangju Zhai Wei Vivian Zhuang Laura J Bierut Dorret I Boomsma Heather A Boyd Laura Crisponi Ellen W Demerath Cornelia M van Duijn Michael J Econs Tamara B Harris David J Hunter Ruth J F Loos Andres Metspalu Grant W Montgomery Paul M Ridker Tim D Spector Elizabeth A Streeten Kari Stefansson Unnur Thorsteinsdottir André G Uitterlinden Elisabeth Widen Joanne M Murabito Ken K Ong Anna Murray

Nat Genet 2010 Dec;42(12):1077-85

Medical Research Council (MRC) Epidemiology Unit, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, UK.

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http://dx.doi.org/10.1038/ng.714DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3140055PMC
December 2010

Low prevalence of NOD2 SNPs in Behçet's disease suggests protective association in Caucasians.

Rheumatology (Oxford) 2009 Nov 11;48(11):1375-7. Epub 2009 Sep 11.

Department of Internal Medicine, Section of Clinical Immunology, Erasmus University Hospital, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1093/rheumatology/kep292DOI Listing
November 2009

Association of the exon 3 deleted/full-length GHR polymorphism with recombinant growth hormone dose in growth hormone-deficient adults.

Pharmacogenomics 2009 Oct;10(10):1599-608

Division of Endocrinology & Diabetology, University Hospital Giessen and Marburg GmbH, Philipps-University Marburg, Baldingerstrasse, 35033 Marburg, Germany.

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http://dx.doi.org/10.2217/pgs.09.91DOI Listing
October 2009

Growth hormone dose in growth hormone-deficient adults is not associated with IGF-1 gene polymorphisms.

Pharmacogenomics 2009 Feb;10(2):293-302

Division of Endocrinology & Diabetology, University Hospital Giessen and Marburg GmbH, Philipps-University Marburg, Baldingerstrasse, 35033 Marburg, Germany.

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http://dx.doi.org/10.2217/14622416.10.2.293DOI Listing
February 2009

The RIZ Pro704 insertion-deletion polymorphism, bone mineral density and fracture risk: the Rotterdam study.

Bone 2008 Feb 23;42(2):286-93. Epub 2007 Oct 23.

Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.bone.2007.10.008DOI Listing
February 2008

The catechol-O-methyltransferase Met158 low-activity allele and association with nonvertebral fracture risk in elderly men.

J Clin Endocrinol Metab 2007 Aug 15;92(8):3206-12. Epub 2007 May 15.

Department of Internal Medicine, Erasmus Medical Center, P.O. Box 1738, 3000 DR Rotterdam, The Netherlands.

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http://dx.doi.org/10.1210/jc.2006-2136DOI Listing
August 2007