Publications by authors named "Lisa R Young"

99Publications

Overview of the ChILD Research Network: A roadmap for progress and success in defining rare diseases.

Pediatr Pulmonol 2020 07;55(7):1819-1827

Section of Pediatric Pulmonology, University of Colorado School of Medicine and Children's Hospital Colorado, Aurora, Colorado.

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July 2020

Hermansky-Pudlak Syndrome.

Semin Respir Crit Care Med 2020 04 12;41(2):238-246. Epub 2020 Apr 12.

Division of Pulmonary Medicine, Children's Hospital of Philadelphia, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.

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April 2020

Approaching Clinical Trials in Childhood Interstitial Lung Disease and Pediatric Pulmonary Fibrosis.

Am J Respir Crit Care Med 2019 11;200(10):1219-1227

Division of Pulmonary Medicine, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.

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November 2019

Children's interstitial and diffuse lung disease.

Lancet Child Adolesc Health 2019 08 18;3(8):568-577. Epub 2019 Jun 18.

Department of Paediatrics, Vanderbilt University, Nashville, TN, USA.

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August 2019

Serum vascular endothelial growth factor-D as a diagnostic and therapeutic biomarker for lymphangioleiomyomatosis.

PLoS One 2019 28;14(2):e0212776. Epub 2019 Feb 28.

Clinical Research Center, National Hospital Organization Kinki-Chuo Chest Medical Center, Sakai, Osaka, Japan.

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December 2019

Consider the lung as a sensory organ: A tip from pulmonary neuroendocrine cells.

Curr Top Dev Biol 2019 2;132:67-89. Epub 2019 Jan 2.

Department of Pediatrics, University of California, San Diego, La Jolla, CA, United States; Department of Biological Sciences, University of California, San Diego, La Jolla, CA, United States. Electronic address:

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August 2019

Localized hypoxia links ER stress to lung fibrosis through induction of C/EBP homologous protein.

JCI Insight 2018 08 23;3(16). Epub 2018 Aug 23.

Department of Medicine, Division of Allergy, Pulmonary and Critical Care Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.

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August 2018

Measures that matter: Health-related quality of life in children with interstitial lung disease.

Pediatr Pulmonol 2018 10 26;53(10):1336-1337. Epub 2018 Jun 26.

Division of Pulmonary Medicine, Center for Childhood Lung Research, Department of Pediatrics, Vanderbilt University Medical Center, Nashville, Tennessee.

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October 2018

Growth trajectories and oxygen use in neuroendocrine cell hyperplasia of infancy.

Pediatr Pulmonol 2018 05 2;53(5):656-663. Epub 2018 Feb 2.

Division of Pulmonary Medicine, Department of Pediatrics, Vanderbilt University Medical Center, Nashville, Tennessee.

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May 2018

Reply: The Genetic Diagnosis of Interstitial Lung Disease: A Need for an International Consensus.

Am J Respir Crit Care Med 2017 06;195(11):1539-1540

1 Vanderbilt University Medical Center Nashville, Tennessee.

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June 2017

Reply: The ATS/JRS Guidelines on Lymphangioleiomyomatosis: Filling in the Gaps.

Am J Respir Crit Care Med 2017 09;196(5):660-661

7 National Heart, Lung, and Blood Institute Bethesda, Maryland For the ATS/JRS Committee on Lymphangioleiomyomatosis.

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September 2017

Epithelial-macrophage interactions determine pulmonary fibrosis susceptibility in Hermansky-Pudlak syndrome.

JCI Insight 2016 Oct 20;1(17):e88947. Epub 2016 Oct 20.

Department of Medicine, Division of Allergy, Pulmonary and Critical Care Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.

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October 2016

Pulmonary Fibrosis in Hermansky-Pudlak Syndrome.

Ann Am Thorac Soc 2016 10;13(10):1839-1846

1 Division of Pulmonary, Critical Care and Sleep Disorders Medicine, Department of Medicine, and Department of Pharmacology and Toxicology, University of Louisville School of Medicine, Louisville, Kentucky.

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October 2016

Hermansky-Pudlak Syndrome.

Clin Chest Med 2016 09 30;37(3):505-11. Epub 2016 Jun 30.

Division of Pulmonary Medicine, Department of Pediatrics, Vanderbilt University School of Medicine, 2200 Children's Way, Doctor's Office Tower 11215, Nashville, TN 37232, USA; Division of Allergy, Pulmonary, and Critical Care, Department of Medicine, Vanderbilt University School of Medicine, 1161 21st Avenue South, B-1220 Medical Center North, Nashville, TN 37232, USA. Electronic address:

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September 2016

Epithelial NF-κB signaling promotes EGFR-driven lung carcinogenesis via macrophage recruitment.

Oncoimmunology 2016 Jun 30;5(6):e1168549. Epub 2016 Mar 30.

Department of Cancer Biology, Vanderbilt University, Nashville, TN, USA; Department of Medicine, Division of Allergy, Pulmonary and Critical Care Medicine, Vanderbilt University Medical Center, Nashville, TN, USA; Department of Veterans Affairs Medical Center, Nashville, TN, USA; Department of Cell and Developmental Biology, Vanderbilt University, Nashville, TN, USA.

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June 2016

Response.

Chest 2016 06;149(6):1579-80

Department of Pediatric Radiology, Texas Children's Hospital, Houston, TX.

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June 2016

Epithelial-Derived Inflammation Disrupts Elastin Assembly and Alters Saccular Stage Lung Development.

Am J Pathol 2016 07 12;186(7):1786-1800. Epub 2016 May 12.

Department of Medicine, Division of Allergy, Pulmonary and Critical Care Medicine, Vanderbilt University Medical Center, Nashville, Tennessee; Department of Cell and Developmental Biology, Vanderbilt University Medical Center, Nashville, Tennessee; Department of Cancer Biology, Vanderbilt University Medical Center, Nashville, Tennessee; Nashville Veterans Affairs Medical Center, Nashville, Tennessee.

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July 2016

Lipofibroblast Phenotype in Pulmonary Interstitial Glycogenosis.

Am J Respir Crit Care Med 2016 Mar;193(6):694-6

2 Vanderbilt University School of Medicine Nashville, Tennessee.

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March 2016

Chronic NF-κB activation links COPD and lung cancer through generation of an immunosuppressive microenvironment in the lungs.

Oncotarget 2016 Feb;7(5):5470-82

Department of Medicine, Division of Allergy, Pulmonary and Critical Care Medicine, Vanderbilt University School of Medicine, Nashville, TN, 37232 USA.

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February 2016

Exacerbations in neuroendocrine cell hyperplasia of infancy are characterized by increased air trapping.

Pediatr Pulmonol 2016 Mar 7;51(3):E9-12. Epub 2015 Dec 7.

Division of Pulmonary Medicine, Department of Pediatrics, Vanderbilt University, Nashville, Tennessee.

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March 2016

Rare Becomes More Common: Recognizing Neuroendocrine Cell Hyperplasia of Infancy in Everyday Pulmonary Consultations.

Ann Am Thorac Soc 2015 Nov;12(11):1730-2

1 Vanderbilt University School of Medicine Nashville, Tennessee.

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November 2015

Update on Diffuse Lung Disease in Children.

Chest 2016 Mar 12;149(3):836-45. Epub 2016 Jan 12.

Pulmonary Medicine, Department of Pediatrics, Vanderbilt University Medical Center, Nashville, TN; Allergy, Pulmonary, and Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN.

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March 2016

AUTOIMMUNE DISEASE. Patients with LRBA deficiency show CTLA4 loss and immune dysregulation responsive to abatacept therapy.

Science 2015 Jul;349(6246):436-40

Division of Bone Marrow Transplantation and Immune Deficiency, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, University of Cincinnati, Cincinnati, OH, USA. Division of Immunobiology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center/ University of Cincinnati, Cincinnati, OH, USA.

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July 2015

"A remarkable experience of god, shaping us as a family": parents' use of faith following child's rare disease diagnosis.

J Health Care Chaplain 2015 ;21(1):25-38

a Division of Pulmonary Medicine , Cincinnati Children's Hospital Medical Center , Cincinnati , Ohio , USA.

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April 2015

Unusual progression and subsequent improvement in cystic lung disease in a child with radiation-induced lung injury.

Pediatr Radiol 2015 Jul 2;45(7):1086-90. Epub 2014 Dec 2.

Department of Pediatrics, Monroe Carell Jr. Children's Hospital at Vanderbilt, Nashville, TN, USA.

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July 2015

Epithelial β1 integrin is required for lung branching morphogenesis and alveolarization.

Development 2014 Dec 13;141(24):4751-62. Epub 2014 Nov 13.

Department of Cell and Developmental Biology, Vanderbilt University Medical Center, Nashville, TN 37232, USA Department of Medicine, Division of Nephrology, Vanderbilt University Medical Center, Nashville, TN 37232, USA Department of Cancer Biology, Vanderbilt University Medical Center, Nashville, TN 37232, USA Nashville Veterans Affairs Medical Center, Nashville, TN 37232, USA

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December 2014

New clinical practice guidelines on the classification, evaluation and management of childhood interstitial lung disease in infants: what do they mean?

Expert Rev Respir Med 2014 Dec 20;8(6):653-5. Epub 2014 Aug 20.

Edward Mallinckrodt Department of Pediatrics, Division of Newborn Medicine, Washington University School of Medicine, St. Louis, MO, USA.

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December 2014

Interstitial lung disease in children.

Curr Opin Pediatr 2014 Jun;26(3):320-7

aDivision of Pediatric Pulmonary Medicine, Lucile Packard Children's Hospital, Stanford University School of Medicine, Stanford, California bDivision of Pediatric Pulmonary Medicine, Monroe Carell Jr Children's Hospital at Vanderbilt cDivision of Allergy, Pulmonary, and Critical Care, Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.

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June 2014

Childhood interstitial lung diseases: an 18-year retrospective analysis.

Pediatrics 2013 Oct 30;132(4):684-91. Epub 2013 Sep 30.

Division of Pulmonary Medicine, Department of Pediatrics, Vanderbilt University School of Medicine, 2200 Children's Way, 11215 Doctor's Office Tower, Nashville, TN 37232-9500.

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October 2013

An atoll variant that mocks.

Am J Respir Crit Care Med 2013 Jul;188(1):110

Department of Internal Medicine, The University of Cincinnati College of Medicine, Cincinnati, OH, USA.

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July 2013

A mutation in TTF1/NKX2.1 is associated with familial neuroendocrine cell hyperplasia of infancy.

Chest 2013 Oct;144(4):1199-1206

Eudowood Neonatal Pulmonary Division, Department of Pediatrics, Johns Hopkins University, Baltimore, MD. Electronic address:

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October 2013

Lymphangioleiomyomatosis screening in women with tuberous sclerosis.

Chest 2013 Aug;144(2):578-585

Division of Pediatric Pulmonary Medicine, Vanderbilt University School of Medicine, Nashville, TN; Division of Allergy, Pulmonary, and Critical Care Medicine, Vanderbilt University School of Medicine, Nashville, TN. Electronic address:

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August 2013

St. George's Respiratory Questionnaire has longitudinal construct validity in lymphangioleiomyomatosis.

Chest 2013 Jun;143(6):1671-1678

Department of Internal Medicine, Division of Pulmonary, Critical Care and Sleep Medicine, University of Cincinnati, Cincinnati, OH.

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June 2013

Genetic studies provide clues on the pathogenesis of idiopathic pulmonary fibrosis.

Dis Model Mech 2013 Jan;6(1):9-17

Department of Medicine, Division of Allergy, Pulmonary and Critical Care Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.

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January 2013

Utility of transbronchial biopsy in the diagnosis of lymphangioleiomyomatosis.

Front Med 2012 Dec 7;6(4):395-405. Epub 2012 Dec 7.

Division of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine, University of Cincinnati School of Medicine, Cincinnati, OH 45529, USA.

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December 2012

Reducing portion sizes to prevent obesity: a call to action.

Am J Prev Med 2012 Nov;43(5):565-8

Department of Nutrition, Food Studies, and Public Health, New York University, New York, New York 10003, USA.

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November 2012

The alveolar epithelium determines susceptibility to lung fibrosis in Hermansky-Pudlak syndrome.

Am J Respir Crit Care Med 2012 Nov 4;186(10):1014-24. Epub 2012 Oct 4.

Division of Pulmonary Medicine, Department of Pediatrics, Vanderbilt University School of Medicine, 2200 Children's Way, 11215 Doctor's Office Tower, Nashville, TN 37232, USA.

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November 2012

Lymphangioleiomyomatosis: new concepts in pathogenesis, diagnosis, and treatment.

Semin Respir Crit Care Med 2012 Oct 21;33(5):486-97. Epub 2012 Sep 21.

Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Internal Medicine, University of Cincinnati School of Medicine, Cincinnati, OH 45267-0564, USA.

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October 2012

Neuroendocrine cell distribution and frequency distinguish neuroendocrine cell hyperplasia of infancy from other pulmonary disorders.

Chest 2011 May 30;139(5):1060-1071. Epub 2010 Sep 30.

Department of Laboratories, Seattle Children's Hospital, University of Washington, Seattle, WA. Electronic address:

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May 2011

Pulmonary interstitial glycogenosis: words of caution.

Pediatr Radiol 2010 Sep 1;40(9):1471-5. Epub 2010 Jul 1.

Department of Laboratories, Department of Pathology, Seattle Children's Hospital, Seattle, WA, USA.

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September 2010

Neuroendocrine cell hyperplasia of infancy: diagnosis with high-resolution CT.

AJR Am J Roentgenol 2010 Jan;194(1):238-44

Department of Radiology, Cincinnati Children's Hospital Medical Center, 3333 Burnet Ave., MLC 5031, Cincinnati, OH 45229, USA.

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January 2010

Pseudomonas aeruginosa exotoxin pyocyanin causes cystic fibrosis airway pathogenesis.

Am J Pathol 2009 Dec 5;175(6):2473-88. Epub 2009 Nov 5.

Department of Surgery, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.

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December 2009

Utility of [18F]2-fluoro-2-deoxyglucose-PET in sporadic and tuberous sclerosis-associated lymphangioleiomyomatosis.

Chest 2009 Sep 6;136(3):926-933. Epub 2009 Apr 6.

Department of Pulmonary, Critical Care, and Sleep Medicine, University of Cincinnati College of Medicine, Cincinnati, OH. Electronic address:

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September 2009

Histologic resolution of pulmonary interstitial glycogenosis.

Pediatr Dev Pathol 2009 Nov-Dec;12(6):475-80

Department of Laboratories, A6901, Seattle Children's Hospital, 4800 Sand Point Way NE, Seattle, WA 98105, USA.

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April 2010

Usual interstitial pneumonia in an adolescent with ABCA3 mutations.

Chest 2008 Jul;134(1):192-5

Division of Pulmonary Medicine, Cincinnati Children's Hospital Medical Center, University of Cincinnati, 3333 Burnet Ave, MLC 2021, Cincinnati, OH 45229-3039, USA.

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July 2008

A kindred of children with interstitial lung disease.

Chest 2007 Jul;132(1):221-30

Cincinnati Children's Hospital Medical Center, University of Cincinnati, Cincinnati, Cincinnati, OH 45267-0564, USA.

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July 2007

Portion sizes and obesity: responses of fast-food companies.

J Public Health Policy 2007 Jul;28(2):238-48

New York University, Nutrition, Food Studies, and Public Health, New York, NY 10012, USA.

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July 2007

Susceptibility of Hermansky-Pudlak mice to bleomycin-induced type II cell apoptosis and fibrosis.

Am J Respir Cell Mol Biol 2007 Jul 15;37(1):67-74. Epub 2007 Mar 15.

University of Cincinnati, Pulmonary, Critical Care, and Sleep Medicine, 231 Albert Sabin Way, Cincinnati, OH 45267, USA.

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July 2007

Persistent tachypnea and hypoxia in a 3-month-old term infant.

J Pediatr 2006 Nov;149(5):702-706

Department of Pediatrics, Division of Pulmonary Medicine, Northwestern University Feinberg School of Medicine, Children's Memorial Hospital, Chicago, IL 60614, USA.

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November 2006

Patient perspectives on management of pneumothorax in lymphangioleiomyomatosis.

Chest 2006 May;129(5):1267-73

Department of Medicine, University of Cincinnati, Division of Pulmonary and Critical Care, Cincinnati, OH 45267-0564, USA.

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May 2006

Lung-restricted macrophage activation in the pearl mouse model of Hermansky-Pudlak syndrome.

J Immunol 2006 Apr;176(7):4361-8

Department of Medicine, Division of Pulmonary and Critical Care, University of Cincinnati, OH 45267, USA.

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April 2006

Lung transplantation exacerbates gastroesophageal reflux disease.

Chest 2003 Nov;124(5):1689-93

Division of Medicine and Pediatrics, University of Cincinnati, Cincinnati, OH, USA.

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November 2003

Expanding portion sizes in the US marketplace: implications for nutrition counseling.

J Am Diet Assoc 2003 Feb;103(2):231-4

Department of Nutrition and Food Studies, New York University, NY 10012-1172, USA.

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February 2003

The contribution of expanding portion sizes to the US obesity epidemic.

Am J Public Health 2002 Feb;92(2):246-9

Department of Nutrition and Food Studies, New York University, New York City, 10012-1172, USA.

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February 2002