Publications by authors named "Lisa Polin"

76Publications

Omeprazole Inhibits Glioblastoma Cell Invasion and Tumor Growth.

Cancers (Basel) 2020 Jul 28;12(8). Epub 2020 Jul 28.

Department of Veterinary Physiology and Pharmacology, College of Veterinary Medicine, Texas A&M University, College Station, TX 77843, USA.

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July 2020

Professor Samuel C. Brooks, Jr., Ph.D. (1928-2019).

Cancer Metastasis Rev 2020 03;39(1):331-332

Department of Oncology, Wayne State University School of Medicine, Karmanos Cancer Institute, Detroit, MI, USA.

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March 2020

Disulfiram and BKM120 in Combination with Chemotherapy Impede Tumor Progression and Delay Tumor Recurrence in Tumor Initiating Cell-Rich TNBC.

Sci Rep 2019 01 18;9(1):236. Epub 2019 Jan 18.

Barbara Ann Karmanos Cancer Institute, Department of Oncology, Wayne State University School of Medicine, 4100 John R, Detroit, MI, USA.

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January 2019

Obesity-induced MBD2_v2 expression promotes tumor-initiating triple-negative breast cancer stem cells.

Mol Oncol 2019 04 1;13(4):894-908. Epub 2019 Mar 1.

Department of Oncology, Barbara Ann Karmanos Cancer Institute, Wayne State University School of Medicine, Detroit, MI, USA.

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April 2019

Tumor hypoxia directed multimodal nanotherapy for overcoming drug resistance in renal cell carcinoma and reprogramming macrophages.

Biomaterials 2018 11 30;183:280-294. Epub 2018 Aug 30.

Use-inspired Biomaterials & Integrated Nano Delivery (U-BiND) Systems Laboratory Department of Pharmaceutical Sciences, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, MI, 48201, USA; Molecular Imaging Program, Barbara Ann Karmanos Cancer Institute, Wayne State University, School of Medicine, Detroit, MI, 48201, USA. Electronic address:

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November 2018

Synthesis and Antileukemic Activities of Piperlongumine and HDAC Inhibitor Hybrids against Acute Myeloid Leukemia Cells.

J Med Chem 2016 09 24;59(17):7974-90. Epub 2016 Aug 24.

Department of Pharmaceutical Sciences, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University , Detroit, Michigan 48201, United States.

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September 2016

Spectroscopic Characterization of the 3+ and 2+ Oxidation States of Europium in a Macrocyclic Tetraglycinate Complex.

Inorg Chem 2016 Oct 31;55(20):9981-9988. Epub 2016 May 31.

Department of Chemistry, Wayne State University , 5101 Cass Avenue, Detroit, Michigan 48202, United States.

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October 2016

Tryptophan PET Imaging of the Kynurenine Pathway in Patient-Derived Xenograft Models of Glioblastoma.

Mol Imaging 2016 5;15. Epub 2016 May 5.

Department of Neurosurgery, Wayne State University, Detroit, MI, USA Department of Oncology, Wayne State University, Detroit, MI, USA Karmanos Cancer Institute, Detroit, MI, USA

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December 2016

Evaluation of Eu(II) -based positive contrast enhancement after intravenous, intraperitoneal, and subcutaneous injections.

Contrast Media Mol Imaging 2016 07 30;11(4):299-303. Epub 2016 Mar 30.

Department of Chemistry, Wayne State University, 5101 Cass Avenue, Detroit, MI, 48202, USA.

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July 2016

Targeting Nonsquamous Nonsmall Cell Lung Cancer via the Proton-Coupled Folate Transporter with 6-Substituted Pyrrolo[2,3-d]Pyrimidine Thienoyl Antifolates.

Mol Pharmacol 2016 Apr 2;89(4):425-34. Epub 2016 Feb 2.

Department of Oncology (M.R.W., Z.H., L.P., J.K., K.W., J.H., M.R., L.H.M.), and Department of Pharmacology (L.H.M.), Wayne State University School of Medicine, Detroit, Michigan; Molecular Therapeutics Program, Barbara Ann Karmanos Cancer Institute, Detroit, Michigan (Z.H., L.P., M.R., L.H.M.); and Division of Medicinal Chemistry, Graduate School of Pharmaceutical Science, Duquesne University, Pittsburgh, Pennsylvania (S.Y., A.G.)

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April 2016

A Eu(II)-Containing Cryptate as a Redox Sensor in Magnetic Resonance Imaging of Living Tissue.

Angew Chem Int Ed Engl 2015 Nov 2;54(48):14398-401. Epub 2015 Oct 2.

Department of Chemistry, Wayne State University, 5101 Cass Avenue, Detroit, MI 48202 (USA) http://chem.wayne.edu/allengroup.

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November 2015

Protein expression of DNA damage repair proteins dictates response to topoisomerase and PARP inhibitors in triple-negative breast cancer.

PLoS One 2015 16;10(3):e0119614. Epub 2015 Mar 16.

Department of Oncology, Wayne State University, Barbara Ann Karmanos Cancer Institute, Detroit, Michigan, United States of America.

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February 2016

A novel ER-microtubule-binding protein, ERLIN2, stabilizes Cyclin B1 and regulates cell cycle progression.

Cell Discov 2015 8;1:15024. Epub 2015 Sep 8.

Center for Molecular Medicine and Genetics, Wayne State University School of Medicine, Detroit, MI, USA; Karmanos Cancer Institute, Wayne State University School of Medicine, Detroit, MI, USA; Department of Immunology and Microbiology, Wayne State University School of Medicine, Detroit, MI, USA.

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July 2016

Disulfiram suppresses growth of the malignant pleural mesothelioma cells in part by inducing apoptosis.

PLoS One 2014 1;9(4):e93711. Epub 2014 Apr 1.

Barbara Ann Karmanos Cancer Institute, Detroit, Michigan, United States of America; Department of Oncology, Wayne State University, Detroit, Michigan, United States of America; John D. Dingell VA Medical Center, Detroit, Michigan, United States of America.

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June 2015

CARP-1 functional mimetics: a novel class of small molecule inhibitors of medulloblastoma cell growth.

PLoS One 2013 24;8(6):e66733. Epub 2013 Jun 24.

Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh, Kingdom of Saudi Arabia.

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January 2014

Withaferin A inhibits the proteasome activity in mesothelioma in vitro and in vivo.

PLoS One 2012 17;7(8):e41214. Epub 2012 Aug 17.

Karmanos Cancer Institute, Wayne State University, Detroit, Michigan, United States of America.

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April 2013

Cullin-3 protein expression levels correlate with breast cancer progression.

Cancer Biol Ther 2012 Sep 24;13(11):1042-6. Epub 2012 Jul 24.

Karmanos Cancer Institute, Detroit, MI ,USA.

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September 2012

Functional loss of the reduced folate carrier enhances the antitumor activities of novel antifolates with selective uptake by the proton-coupled folate transporter.

Mol Pharmacol 2012 Oct 26;82(4):591-600. Epub 2012 Jun 26.

Graduate Program in Cancer Biology and Department of Oncology, Wayne State University School of Medicine, Detroit, Michigan, USA.

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October 2012

The E3 ligase Itch and deubiquitinase Cyld act together to regulate Tak1 and inflammation.

Nat Immunol 2011 Nov 6;12(12):1176-83. Epub 2011 Nov 6.

Karmanos Cancer Institute, Department of Oncology, Wayne State University School of Medicine, Detroit, Michigan, USA.

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November 2011

Identification and biological activities of new taccalonolide microtubule stabilizers.

J Med Chem 2011 Sep 11;54(17):6117-24. Epub 2011 Aug 11.

Department of Pharmacology, University of Texas Health Science Center at San Antonio, San Antonio, Texas 78229, USA.

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September 2011

Curcumin suppresses growth of mesothelioma cells in vitro and in vivo, in part, by stimulating apoptosis.

Mol Cell Biochem 2011 Nov 19;357(1-2):83-94. Epub 2011 May 19.

John D. Dingell VA Medical Center, Karmanos Cancer Institute, Wayne State University, VAMC, 4646 John R, Detroit, MI 48201, USA.

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November 2011

Cell cycle and apoptosis regulatory protein (CARP)-1 is a novel, adriamycin-inducible, diffuse large B-cell lymphoma (DLBL) growth suppressor.

Cancer Chemother Pharmacol 2011 Jun 31;67(6):1401-13. Epub 2010 Aug 31.

Room B4334, Veterans Affairs Medical Center, Wayne State University, 4646 John R, Detroit, MI 48201, USA.

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June 2011

The taccalonolides: microtubule stabilizers that circumvent clinically relevant taxane resistance mechanisms.

Cancer Res 2008 Nov;68(21):8881-8

Department of Physiology and Medicine, Southwest Foundation for Biomedical Research, University of Texas Health Science Center, San Antonio, Texas 78229-3900, USA.

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November 2008

The role of autophagy in the death of L1210 leukemia cells initiated by the new antitumor agents, XK469 and SH80.

Mol Cancer Ther 2007 Jan;6(1):370-9

Department of Pharmacology, Wayne State University School of Medicine, Detroit, MI 48201, USA.

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January 2007

Novel in vitro model barriers for evaluation of the permeability of antitumor compounds, thioxanthones.

Invest New Drugs 2006 Mar;24(2):111-6

Department of Pharmaceutics & Medicinal Chemistry, TJ Long School of Pharmacy & Health Sciences, University of the Pacific, Stockton, CA 95211, USA.

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March 2006

Synthesis and biological evaluation of conformationally constrained analogs of the antitumor agents XK469 and SH80. Part 5.

Bioorg Med Chem 2006 Apr 5;14(7):2462-7. Epub 2005 Dec 5.

Department of Internal Medicine, Division of Hematology and Oncology, Wayne State University School of Medicine, Barbara Ann Karmanos Cancer Institute, Detroit, MI, USA.

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April 2006

Synthesis, antiviral, and antitumor activity of 2-substituted purine methylenecyclopropane analogues of nucleosides.

Bioorg Med Chem 2006 Feb 18;14(4):1247-54. Epub 2005 Oct 18.

Developmental Therapeutics Program, Barbara Ann Karmanos Cancer Institute, Wayne State University School of Medicine, Detroit, MI 48201-1379, USA.

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February 2006

Divalent cations influence colon cancer cell adhesion in a murine transplantable tumor model.

Am J Surg 2005 Nov;190(5):701-7

Wayne State University, John D. Dingell VAMC, 4646 John R. Street, Detroit, MI 48201-1932, USA.

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November 2005

CB694, a novel antimitotic with antitumor activities.

Int J Cancer 2006 Feb;118(4):1032-40

Department of Physiology and Medicine, Southwest Foundation for Biomedical Research, San Antonio, TX 78425-0549, USA.

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February 2006

Synthetic modification of the 2-oxypropionic acid moiety in 2-{4-[(7-chloro-2-quinoxalinyl)oxy]phenoxy}propionic acid (XK469), and consequent antitumor effects. Part 4.

Bioorg Med Chem 2005 Jun;13(12):3910-20

Department of Internal Medicine, Division of Hematology and Oncology, Barbara Ann Karmanos Cancer Institute, Wayne State University School of Medicine, Detroit, MI, USA.

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June 2005

An in vivo evaluation of docetaxel delivered intratumorally in head and neck squamous cell carcinoma.

Arch Otolaryngol Head Neck Surg 2005 May;131(5):418-29

Department of Otolaryngology-Head and Neck Surgery, Division of Hematology/Oncology, Wayne State University, Detroit, MI 48201, USA.

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May 2005

Part 3: synthesis and biological evaluation of some analogs of the antitumor agents, 2-{4-[(7-chloro-2-quinoxalinyl)oxy]phenoxy}propionic acid, and 2-{4-[(7-bromo-2-quinolinyl)oxy]phenoxy}propionic acid.

Bioorg Med Chem 2005 Feb;13(4):1069-81

Department of Internal Medicine, Division of Hematology and Oncology, Wayne State University, School of Medicine, Barbara Ann Karmanos Cancer Institute, Detroit, MI, USA.

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February 2005

Discovery and preclinical antitumor efficacy evaluations of LY32262 and LY33169.

Invest New Drugs 2003 Feb;21(1):33-45

Barbara Ann Karmanos Cancer Institute, Wayne State University School of Medicine, Detroit, MI 48201, USA.

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February 2003