Publications by authors named "Lisa H Butterfield"

100Publications

Dysregulated NF-κB-Dependent ICOSL Expression in Human Dendritic Cell Vaccines Impairs T-cell Responses in Patients with Melanoma.

Cancer Immunol Res 2020 Oct 13. Epub 2020 Oct 13.

Parker Institute for Cancer Immunotherapy, and University of California San Francisco, Microbiology and Immunology, San Francisco, California.

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http://dx.doi.org/10.1158/2326-6066.CIR-20-0274DOI Listing
October 2020

Improving the therapeutic index in adoptive cell therapy: key factors that impact efficacy.

J Immunother Cancer 2020 Oct;8(2)

Research & Development, Refuge Biotechnologies, Menlo Park, California, USA

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http://dx.doi.org/10.1136/jitc-2020-001619DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7539608PMC
October 2020

Impact of checkpoint blockade on cancer vaccine-activated CD8+ T cell responses.

J Exp Med 2020 Jul;217(7)

University of Pittsburgh Medical Center, Hillman Cancer Center, University of Pittsburgh, Pittsburgh, PA.

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http://dx.doi.org/10.1084/jem.20191369DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7336310PMC
July 2020

The great debate at "Immunotherapy Bridge 2018", Naples, November 29th, 2018.

J Immunother Cancer 2019 08 15;7(1):221. Epub 2019 Aug 15.

Department of Medicine, Roswell Park Comprehensive Cancer Center, Developmental Therapeutics, Buffalo, New York, USA.

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http://dx.doi.org/10.1186/s40425-019-0683-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696687PMC
August 2019

Multiple antigen-engineered DC vaccines with or without IFNα to promote antitumor immunity in melanoma.

J Immunother Cancer 2019 04 24;7(1):113. Epub 2019 Apr 24.

Department of Medicine, University of Pittsburgh, UPMC Hillman Cancer Center, 5117 Centre Avenue, Suite 1.27, Pittsburgh, PA, 15213, USA.

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http://dx.doi.org/10.1186/s40425-019-0552-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6480917PMC
April 2019

Tumor-Derived α-Fetoprotein Suppresses Fatty Acid Metabolism and Oxidative Phosphorylation in Dendritic Cells.

Cancer Immunol Res 2019 06 15;7(6):1001-1012. Epub 2019 Apr 15.

UPMC Hillman Cancer Center, Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1158/2326-6066.CIR-18-0513DOI Listing
June 2019

Interleukin 32 expression in human melanoma.

J Transl Med 2019 04 5;17(1):113. Epub 2019 Apr 5.

Department of Surgery, University of California, Los Angeles, 10833 Le Conte Ave, Los Angeles, CA, 90095, USA.

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http://dx.doi.org/10.1186/s12967-019-1862-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449995PMC
April 2019

Next Steps for Immune Checkpoints in Hepatocellular Carcinoma.

Gastroenterology 2018 12 9;155(6):1684-1686. Epub 2018 Nov 9.

Department of Medicine and Department of Immunology and Department of Surgery and Department of Clinical and Translational Science, University of Pittsburgh, Pittsburgh, Pennsylvania. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2018.11.008DOI Listing
December 2018

Hepatocellular cancer-derived alpha fetoprotein uptake reduces CD1 molecules on monocyte-derived dendritic cells.

Cell Immunol 2019 01 1;335:59-67. Epub 2018 Nov 1.

UPMC Hillman Cancer Center, Pittsburgh, PA, United States; Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States; Department of Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States; Clinical and Translational Science, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00088749183036
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http://dx.doi.org/10.1016/j.cellimm.2018.10.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368446PMC
January 2019

Prospective Analyses of Cytokine Mediation of Sleep and Survival in the Context of Advanced Cancer.

Psychosom Med 2018 06;80(5):483-491

From the Departments of Surgery, Psychiatry, and Psychology (Steel), Occupational Therapy (Terhorst), Surgery, Mathematica Policy Research (Collins), Surgery (Geller, Vodovotz, Kim, Krane, Marsh, Tsung), University of Pittsburg, Pennsylvania; Department of Psychology (Antoni), University of Miami, Florida; School of Nursing (Burke), and Department of Medicine, Surgery and Immunology (Butterfield), University of Pittsburgh, Pennsylvania; Department of Medical Social Sciences, Psychology, and Psychiatry and Behavioral Sciences (Penedo), Northwestern University, Evantson, Illinois; and Department of Psychiatry (Buysse), University of Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1097/PSY.0000000000000579DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5976532PMC
June 2018

Three antigen-loading methods in dendritic cell vaccines for metastatic melanoma.

Melanoma Res 2018 06;28(3):211-221

Department of Dermatology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.

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http://dx.doi.org/10.1097/CMR.0000000000000441DOI Listing
June 2018

Dendritic Cell-Based Cancer Vaccines.

J Immunol 2018 01;200(2):443-449

UPMC Hillman Cancer Center, Pittsburgh, PA 15213;

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http://dx.doi.org/10.4049/jimmunol.1701024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880540PMC
January 2018

High PD-L1/CD86 MFI ratio and IL-10 secretion characterize human regulatory dendritic cells generated for clinical testing in organ transplantation.

Cell Immunol 2018 01 14;323:9-18. Epub 2017 Sep 14.

Starzl Transplantation Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States; Department of Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States. Electronic address:

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http://dx.doi.org/10.1016/j.cellimm.2017.08.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5835175PMC
January 2018

Therapeutic reduction of cell-mediated immunosuppression in mycosis fungoides and Sézary syndrome.

Cancer Immunol Immunother 2018 03 4;67(3):423-434. Epub 2017 Dec 4.

Department of Dermatology, University of Pittsburgh, Suite 500.68 Medical Arts Building, 3708 Fifth Avenue, Pittsburgh, PA, 15213, USA.

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http://dx.doi.org/10.1007/s00262-017-2090-zDOI Listing
March 2018

The Society for Immunotherapy of Cancer Biomarkers Task Force recommendations review.

Semin Cancer Biol 2018 10 22;52(Pt 2):12-15. Epub 2017 Sep 22.

Departments of Medicine, Surgery, Immunology and Clinical and Translational Science, University of Pittsburgh, Pittsburgh, PA 15213, United States. Electronic address:

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http://dx.doi.org/10.1016/j.semcancer.2017.09.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862764PMC
October 2018

Highlights of the 31st annual meeting of the Society for Immunotherapy of Cancer (SITC), 2016.

J Immunother Cancer 2017 07 18;5(1):55. Epub 2017 Jul 18.

Department of Medicine, Surgery and Immunology, University of Pittsburgh Cancer Institute, 5117 Centre Avenue, Pittsburgh, PA, 15213, USA.

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http://dx.doi.org/10.1186/s40425-017-0262-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514521PMC
July 2017

Tumor-Derived α-Fetoprotein Directly Drives Human Natural Killer-Cell Activation and Subsequent Cell Death.

Cancer Immunol Res 2017 06 3;5(6):493-502. Epub 2017 May 3.

University of Pittsburgh Cancer Institute, University of Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1158/2326-6066.CIR-16-0216DOI Listing
June 2017

Melanoma antigen-specific effector T cell cytokine secretion patterns in patients treated with ipilimumab.

J Transl Med 2017 02 21;15(1):39. Epub 2017 Feb 21.

Division of Hematology-Oncology, Department of Medicine, University of Pittsburgh, University of Pittsburgh Cancer Institute, 5150 Centre Avenue (555), Pittsburgh, PA, 15232, USA.

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http://dx.doi.org/10.1186/s12967-017-1140-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5319167PMC
February 2017

Validation of biomarkers to predict response to immunotherapy in cancer: Volume I - pre-analytical and analytical validation.

J Immunother Cancer 2016 15;4:76. Epub 2016 Nov 15.

National Cancer Institute, Cancer Diagnosis Program, DCTD, National Institutes of Health, 9609 Medical Center Drive, Bethesda, 20892 MD USA ; Adaptive Biotechnologies, Inc, 1551 Eastlake Ave. E, Seattle, WA 98102 USA.

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http://dx.doi.org/10.1186/s40425-016-0178-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5109744PMC
February 2018

Cancer immunotherapy trials: leading a paradigm shift in drug development.

J Immunother Cancer 2016 19;4:42. Epub 2016 Jul 19.

Division of Surgical Oncology, Rutgers Cancer Institute of New Jersey, New Brunswick, NJ USA.

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http://dx.doi.org/10.1186/s40425-016-0146-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4949883PMC
July 2016

Phenotypic and functional testing of circulating regulatory T cells in advanced melanoma patients treated with neoadjuvant ipilimumab.

J Immunother Cancer 2016 21;4:38. Epub 2016 Jun 21.

University of Pittsburgh Cancer Institute, UPMC Cancer Pavilion, 5150 Centre Avenue (555), Pittsburgh, PA 15232 USA.

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http://dx.doi.org/10.1186/s40425-016-0141-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915044PMC
June 2016

Prolonged intralymphatic delivery of dendritic cells through implantable lymphatic ports in patients with advanced cancer.

J Immunother Cancer 2016 19;4:24. Epub 2016 Apr 19.

Department of Surgery, Division of Surgical Oncology, Hillman Cancer Center, UPCI Cancer Pavilion, Suite 400, 5150 Centre Avenue, Pittsburgh, PA 15213-1863 USA ; University of Pittsburgh Cancer Institute, Hillman Cancer Center, UPCI Cancer Pavilion, Suite 500, 5150 Centre Avenue, Pittsburgh, PA 15213-1863 USA ; Department of Immunology, Hillman Cancer Center, UPCI Research Pavilion, Suite 1.46, 5117 Centre Avenue, Pittsburgh, PA 15213-1863 USA ; Department of Infectious Diseases and Microbiology, Hillman Cancer Center, UPCI Research Pavilion, Suite 1.46, 5117 Centre Avenue, Pittsburgh, PA 15213-1863 USA ; Department of Bioengineering University of Pittsburgh, Hillman Cancer Center, UPCI Research Pavilion, Suite 1.46, 5117 Centre Avenue, Pittsburgh, PA 15213-1863 USA.

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http://dx.doi.org/10.1186/s40425-016-0128-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4835859PMC
April 2016

Immune responses and outcome after vaccination with glioma-associated antigen peptides and poly-ICLC in a pilot study for pediatric recurrent low-grade gliomas.

Neuro Oncol 2016 08 15;18(8):1157-68. Epub 2016 Mar 15.

Department of Neurosurgery, University of Pittsburgh, Pittsburgh, Pennsylvania (I.F.P., H.O.); Department of Pediatrics, University of Pittsburgh, Pittsburgh, Pennsylvania (R.I.J., A.K.C., S.D., G.M.); Department of Pathology, University of Pittsburgh, Pittsburgh, Pennsylvania (R.L.H., T.L.W.); Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania (L.H.B.), Department of Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania (L.H.B., H.O.), Department of Radiology, University of Pittsburgh, Pittsburgh, Pennsylvania (A.P.), Department of Immunology, University of Pittsburgh, Pittsburgh, Pennsylvania (L.H.B., T.L.W.), University of Pittsburgh School of Medicine, Children's Hospital of Pittsburgh, University of Pittsburgh, Pittsburgh, Pennsylvania (I.F.P., R.I.J., A.P., A.K.C., S.D., G.M.); University of Pittsburgh Cancer Institute, University of Pittsburgh, Pittsburgh, Pennsylvania (I.F.P., R.I.J., L.H.B., R.L.H., D.P.N., G.M., T.L.W., H.O.); Department of Biostatistics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania (D.P.N.); Department of Neurosurgery, University of CaliforniaSan Francisco, San Francisco, California (H.O.).

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http://dx.doi.org/10.1093/neuonc/now026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933485PMC
August 2016

Prospective Clinical Testing of Regulatory Dendritic Cells in Organ Transplantation.

Front Immunol 2016 28;7:15. Epub 2016 Jan 28.

Department of Surgery, Starzl Transplantation Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.

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http://dx.doi.org/10.3389/fimmu.2016.00015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4729892PMC
February 2016

Lessons learned from cancer vaccine trials and target antigen choice.

Cancer Immunol Immunother 2016 07 3;65(7):805-12. Epub 2016 Feb 3.

University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1007/s00262-016-1801-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4919159PMC
July 2016

Baseline circulating IL-17 predicts toxicity while TGF-β1 and IL-10 are prognostic of relapse in ipilimumab neoadjuvant therapy of melanoma.

J Immunother Cancer 2015 15;3:39. Epub 2015 Sep 15.

University of Pittsburgh Cancer Institute, UPMC Cancer Pavilion, 5150 Centre Avenue (555), Pittsburgh, PA 15232 USA.

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http://dx.doi.org/10.1186/s40425-015-0081-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4570556PMC
September 2015

Randomized, Placebo-Controlled, Phase III Trial of Yeast-Derived Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF) Versus Peptide Vaccination Versus GM-CSF Plus Peptide Vaccination Versus Placebo in Patients With No Evidence of Disease After Complete Surgical Resection of Locally Advanced and/or Stage IV Melanoma: A Trial of the Eastern Cooperative Oncology Group-American College of Radiology Imaging Network Cancer Research Group (E4697).

J Clin Oncol 2015 Dec 8;33(34):4066-76. Epub 2015 Sep 8.

David H. Lawson, Winship Cancer Institute of Emory University, Atlanta, GA; Sandra Lee and Fengmin Zhao, Dana-Farber Cancer Institute; Michael B. Atkins, Beth Israel Deaconess Medical Center, Boston, MA; Ahmad A. Tarhini, Theresa L. Whiteside, Lisa H. Butterfield, and John M. Kirkwood, University of Pittsburgh Medical Center, Pittsburgh, PA; Kim A. Margolin, Seattle Cancer Care Alliance, Seattle, WA; Marc S. Ernstoff, Dartmouth-Hitchcock Medical Center, Lebanon, NH; and Gary I. Cohen, Greater Baltimore Medical Center, Baltimore, MD.

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http://dx.doi.org/10.1200/JCO.2015.62.0500DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669592PMC
December 2015

Route of antigen delivery impacts the immunostimulatory activity of dendritic cell-based vaccines for hepatocellular carcinoma.

J Immunother Cancer 2015 21;3:32. Epub 2015 Jul 21.

Departments of Medicine, Pittsburgh, PA 15261 USA ; Departments of Surgery, Pittsburgh, PA 15261 USA ; Departments of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261 USA ; University of Pittsburgh Cancer Institute, Hillman Cancer Center 5117 Centre Avenue, Suite 1.27, Pittsburgh, PA 15213 USA.

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http://dx.doi.org/10.1186/s40425-015-0077-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4509479PMC
July 2015

Cancer vaccines.

BMJ 2015 Apr 22;350:h988. Epub 2015 Apr 22.

Departments of Medicine, Surgery and Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4707521PMC
http://dx.doi.org/10.1136/bmj.h988DOI Listing
April 2015

Preamble to the 2015 SITC immunotherapy biomarkers taskforce.

J Immunother Cancer 2015 24;3. Epub 2015 Mar 24.

Sidra Medical and Research Center, Doha, Qatar.

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http://dx.doi.org/10.1186/s40425-015-0052-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4371796PMC
March 2015

Dendritic cell control of immune responses.

Front Immunol 2015 5;6:42. Epub 2015 Feb 5.

University of Pittsburgh , Pittsburgh, PA , USA.

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http://dx.doi.org/10.3389/fimmu.2015.00042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4318395PMC
February 2015

Induction of robust type-I CD8+ T-cell responses in WHO grade 2 low-grade glioma patients receiving peptide-based vaccines in combination with poly-ICLC.

Clin Cancer Res 2015 Jan 25;21(2):286-94. Epub 2014 Nov 25.

Brain Tumor Program, University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania. Department of Neurological Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania. Department of Neurology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1158/1078-0432.CCR-14-1790DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4297523PMC
January 2015

Tumor-derived α-fetoprotein impairs the differentiation and T cell stimulatory activity of human dendritic cells.

J Immunol 2014 Dec 29;193(11):5723-32. Epub 2014 Oct 29.

Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213; Department of Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213; and University of Pittsburgh Cancer Institute, Pittsburgh, PA 15213

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http://dx.doi.org/10.4049/jimmunol.1400725DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4239186PMC
December 2014

Measurements of natural killer (NK) cells.

Crit Rev Oncog 2014 ;19(1-2):47-55

University of Pittsburgh School of Medicine and University of Pittsburgh Cancer Institute, Pittsburgh, PA 15213.

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http://dx.doi.org/10.1615/critrevoncog.2014010829DOI Listing
September 2014

Alpha fetoprotein DNA prime and adenovirus boost immunization of two hepatocellular cancer patients.

J Transl Med 2014 Apr 5;12:86. Epub 2014 Apr 5.

University of Pittsburgh Cancer Institute, Departments of Medicine, Surgery, and Immunology, University of Pittsburgh, 5117 Centre Avenue, PA, Pittsburgh 15213, USA.

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http://dx.doi.org/10.1186/1479-5876-12-86DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4021640PMC
April 2014

Phase I dendritic cell p53 peptide vaccine for head and neck cancer.

Clin Cancer Res 2014 May 28;20(9):2433-44. Epub 2014 Feb 28.

Authors' Affiliations: Cancer Immunology Program; Biostatistics Facility, University of Pittsburgh Cancer Institute; Departments of Pathology and Otolaryngology, University of Pittsburgh School of Medicine; Division of Hematology/Oncology, Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Medicine, Hematology/Oncology, University of Texas-San Antonio Cancer Center, San Antonio, Texas; and Department of Otolaryngology, University of Ulm, Germany.

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http://dx.doi.org/10.1158/1078-0432.CCR-13-2617DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4017234PMC
May 2014

Dendritic cells in cancer immunotherapy clinical trials: are we making progress?

Front Immunol 2013 Dec 13;4:454. Epub 2013 Dec 13.

Departments of Medicine, Surgery and Immunology, University of Pittsburgh Cancer Institute, University of Pittsburgh , Pittsburgh, PA , USA.

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http://dx.doi.org/10.3389/fimmu.2013.00454DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3861778PMC
December 2013

Molecular mimicry of MAGE-A6 and HF-2 epitopes in the induction of antitumor CD8 T-cell responses.

Oncoimmunology 2014;3(8):e954501. Epub 2014 Nov 14.

University of Pittsburgh Cancer Institute ; Pittsburgh, PA USA ; University of Pittsburgh School of Medicine; Department of Medicine ; Pittsburgh, PA USA ; University of Pittsburgh School of Medicine; Department of Immunology ; Pittsburgh, PA USA ; University of Pittsburgh School of Medicine; Department of Surgery ; Pittsburgh, PA USA.

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http://dx.doi.org/10.4161/21624011.2014.954501DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368152PMC
November 2014

Immunologic monitoring of cancer vaccine trials using the ELISPOT assay.

Methods Mol Biol 2014 ;1102:71-82

University of Pittsburgh Cancer Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1007/978-1-62703-727-3_5DOI Listing
June 2014

Epitope-optimized alpha-fetoprotein genetic vaccines prevent carcinogen-induced murine autochthonous hepatocellular carcinoma.

Hepatology 2014 Apr 18;59(4):1448-58. Epub 2014 Feb 18.

Cancer Immunology, Inflammation, and Tolerance Program, Georgia Regents University Cancer Center, Medical College of Georgia, Augusta, GA.

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http://dx.doi.org/10.1002/hep.26893DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4151349PMC
April 2014

Ependymomas: development of immunotherapeutic strategies.

Expert Rev Neurother 2013 Oct;13(10):1089-98

Department of Neurosurgery, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.

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http://www.tandfonline.com/doi/full/10.1586/14737175.2013.84
Publisher Site
http://dx.doi.org/10.1586/14737175.2013.840420DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3972122PMC
October 2013

Melanoma-associated leukoderma - immunology in black and white?

Pigment Cell Melanoma Res 2013 Nov 9;26(6):796-804. Epub 2013 Oct 9.

University of Pittsburgh Cancer Institute, Pittsburgh, PA, USA; Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1111/pcmr.12161DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3855876PMC
November 2013

Cellular immunity induced by a recombinant adenovirus- human dendritic cell vaccine for melanoma.

J Immunother Cancer 2013 18;1:19. Epub 2013 Nov 18.

Department of Medicine, University of Pittsburgh Cancer Institute, 5117 Centre Avenue, Suite 1.27, Pittsburgh, PA 15213, USA ; Department of Surgery, University of Pittsburgh Cancer Institute, 5117 Centre Avenue, Suite 1.27, Pittsburgh, PA 15213, USA ; Department of Immunology, University of Pittsburgh Cancer Institute, 5117 Centre Avenue, Suite 1.27, Pittsburgh, PA 15213, USA ; University of Pittsburgh Cancer Institute, 5117 Centre Avenue, Suite 1.27, Pittsburgh, PA 15213, USA.

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http://dx.doi.org/10.1186/2051-1426-1-19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4019908PMC
May 2014

Adenovirus-engineered human dendritic cells induce natural killer cell chemotaxis via CXCL8/IL-8 and CXCL10/IP-10.

Oncoimmunology 2012 Jul;1(4):448-457

University of Pittsburgh Cancer Institute; Pittsburgh, PA USA ; Deparment of Medicine; University of Pittsburgh School of Medicine; University of Pittsburgh; Pittsburgh, PA USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382881PMC
http://dx.doi.org/10.4161/onci.19788DOI Listing
July 2012

Immunotherapy of hepatocellular carcinoma: Unique challenges and clinical opportunities.

Oncoimmunology 2012 Jan;1(1):48-55

Department of Medicine; University of Pittsburgh School of Medicine; Pittsburgh, PA USA.

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http://dx.doi.org/10.4161/onci.1.1.18344DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3376967PMC
January 2012

Immunotherapy of cancer in 2012.

CA Cancer J Clin 2012 Sep-Oct;62(5):309-35. Epub 2012 May 10.

Melanoma and Skin Cancer Program, University of Pittsburgh Cancer Institute, Hillman Cancer Center, Pittsburgh, PA 15213, USA.

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http://dx.doi.org/10.3322/caac.20132DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3445708PMC
January 2013

Pitfalls in retrospective analyses of biomarkers: a case study with metastatic melanoma patients.

J Immunol Methods 2012 Feb 21;376(1-2):108-12. Epub 2011 Dec 21.

Biostatistics Facility, University of Pittsburgh Cancer Institute, 201 North Craig Street, Suite 325, Pittsburgh, PA 15213, United States.

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http://dx.doi.org/10.1016/j.jim.2011.12.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3472364PMC
February 2012

Defining the critical hurdles in cancer immunotherapy.

Authors:
Bernard A Fox Dolores J Schendel Lisa H Butterfield Steinar Aamdal James P Allison Paolo Antonio Ascierto Michael B Atkins Jirina Bartunkova Lothar Bergmann Neil Berinstein Cristina C Bonorino Ernest Borden Jonathan L Bramson Cedrik M Britten Xuetao Cao William E Carson Alfred E Chang Dainius Characiejus A Raja Choudhury George Coukos Tanja de Gruijl Robert O Dillman Harry Dolstra Glenn Dranoff Lindy G Durrant James H Finke Jerome Galon Jared A Gollob Cécile Gouttefangeas Fabio Grizzi Michele Guida Leif Håkansson Kristen Hege Ronald B Herberman F Stephen Hodi Axel Hoos Christoph Huber Patrick Hwu Kohzoh Imai Elizabeth M Jaffee Sylvia Janetzki Carl H June Pawel Kalinski Howard L Kaufman Koji Kawakami Yutaka Kawakami Ulrich Keilholtz Samir N Khleif Rolf Kiessling Beatrix Kotlan Guido Kroemer Rejean Lapointe Hyam I Levitsky Michael T Lotze Cristina Maccalli Michele Maio Jens-Peter Marschner Michael J Mastrangelo Giuseppe Masucci Ignacio Melero Cornelius Melief William J Murphy Brad Nelson Andrea Nicolini Michael I Nishimura Kunle Odunsi Pamela S Ohashi Jill O'Donnell-Tormey Lloyd J Old Christian Ottensmeier Michael Papamichail Giorgio Parmiani Graham Pawelec Enrico Proietti Shukui Qin Robert Rees Antoni Ribas Ruggero Ridolfi Gerd Ritter Licia Rivoltini Pedro J Romero Mohamed L Salem Rik J Scheper Barbara Seliger Padmanee Sharma Hiroshi Shiku Harpreet Singh-Jasuja Wenru Song Per Thor Straten Hideaki Tahara Zhigang Tian Sjoerd H van Der Burg Paul von Hoegen Ena Wang Marij Jp Welters Hauke Winter Tara Withington Jedd D Wolchok Weihua Xiao Laurence Zitvogel Heinz Zwierzina Francesco M Marincola Thomas F Gajewski Jon M Wigginton Mary L Disis

J Transl Med 2011 Dec 14;9:214. Epub 2011 Dec 14.

Earle A, Chiles Research Institute, Robert W, Franz Research Center, Providence Cancer Center, Providence Portland Medical Center, Portland, OR, USA.

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http://dx.doi.org/10.1186/1479-5876-9-214DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338100PMC
December 2011

A short course of neoadjuvant IRX-2 induces changes in peripheral blood lymphocyte subsets of patients with head and neck squamous cell carcinoma.

Cancer Immunol Immunother 2012 Jun 23;61(6):783-8. Epub 2011 Nov 23.

Research Pavilion at the Hillman Cancer Center, University of Pittsburgh Cancer Institute, 5117 Centre Avenue, Pittsburgh, PA 15213-1863, USA.

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http://dx.doi.org/10.1007/s00262-011-1136-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3721338PMC
June 2012

Multiplex serum biomarker assessments: technical and biostatistical issues.

J Transl Med 2011 Oct 11;9:173. Epub 2011 Oct 11.

University of Pittsburgh Cancer Institute, Pittsburgh, PA 15213, USA.

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http://translational-medicine.biomedcentral.com/articles/10.
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http://dx.doi.org/10.1186/1479-5876-9-173DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3200183PMC
October 2011

Dendritic cell-based vaccines positively impact natural killer and regulatory T cells in hepatocellular carcinoma patients.

Clin Dev Immunol 2011 28;2011:249281. Epub 2011 Sep 28.

Department of Medicine, University of Pittsburgh Cancer Institute, Pittsburgh, PA 15213, USA.

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http://www.hindawi.com/journals/jir/2011/249281/
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http://dx.doi.org/10.1155/2011/249281DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3182577PMC
January 2012

Dendritic cells in cancer immunotherapy: vaccines or autologous transplants?

Immunol Res 2011 Aug;50(2-3):235-47

Department of Surgery, University of Pittsburgh, Pittsburgh, PA 15213-1863, USA.

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http://dx.doi.org/10.1007/s12026-011-8224-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3695396PMC
August 2011