Lisa Giovannelli

Lisa Giovannelli

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Lisa Giovannelli

Lisa Giovannelli

Publications by authors named "Lisa Giovannelli"

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47Publications

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miR-210-3p mediates metabolic adaptation and sustains DNA damage repair of resistant colon cancer cells to treatment with 5-fluorouracil.

Mol Carcinog 2019 Aug 29. Epub 2019 Aug 29.

Department of Experimental and Clinical Biomedical Sciences, University of Florence, Florence, Italy.

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http://dx.doi.org/10.1002/mc.23107DOI Listing
August 2019

Dietary Extra-Virgin Olive Oil Polyphenols Do Not Attenuate Colon Inflammation in Transgenic HLAB-27 Rats but Exert Hypocholesterolemic Effects through the Modulation of HMGCR and PPAR-α Gene Expression in the Liver.

Lifestyle Genom 2018 10;11(2):99-108. Epub 2019 Jan 10.

Section of Pharmacology and Toxicology, Department of Neuroscience, Psychology, Drug Research, and Child Health - NEUROFARBA, University of Florence, Florence, Italy,

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https://www.karger.com/Article/FullText/495516
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http://dx.doi.org/10.1159/000495516DOI Listing
July 2019

The comet assay for human biomonitoring: Effect of cryopreservation on DNA damage in different blood cell preparations.

Mutat Res 2019 Jul 14;843:11-17. Epub 2019 Feb 14.

Dept. NEUROFARBA, Section Pharmacology and Toxicology, University of Florence, Florence, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.mrgentox.2019.02.002DOI Listing
July 2019

Folate, genomic stability and colon cancer: The use of single cell gel electrophoresis in assessing the impact of folate in vitro, in vivo and in human biomonitoring.

Mutat Res 2019 Jul 5;843:73-80. Epub 2018 Sep 5.

Natural Products Group, Division of Lifelong Health, Rowett Institute of Nutrition and Health, University of Aberdeen, Aberdeen, UK; School of Pharmacy and Life Sciences, Robert Gordon University, Aberdeen, UK. Electronic address:

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http://dx.doi.org/10.1016/j.mrgentox.2018.08.012DOI Listing
July 2019

Chronic Resveratrol Treatment Reduces the Pro-angiogenic Effect of Human Fibroblast "Senescent-Associated Secretory Phenotype" on Endothelial Colony-Forming Cells: The Role of IL8.

J Gerontol A Biol Sci Med Sci 2019 Apr;74(5):625-633

Department of Experimental and Clinical Biomedical Science "Mario Serio", Section of Experimental Pathology and Oncology, University of Florence.

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https://academic.oup.com/biomedgerontology/advance-article/d
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http://dx.doi.org/10.1093/gerona/gly175DOI Listing
April 2019

Serpin A1 and the modulation of type I collagen turnover: Effect of the C-terminal peptide 409-418 (SA1-III) in human dermal fibroblasts.

Cell Biol Int 2018 Sep 29;42(10):1340-1348. Epub 2018 Jun 29.

NEUROFARBA Department, Pharmacology and Toxicology Section, University of Florence, Viale G. Pieraccini 6, Florence, 50134, Italy.

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http://dx.doi.org/10.1002/cbin.11018DOI Listing
September 2018

Characterization of serious adverse drug reactions as cause of emergency department visit in children: a 5-years active pharmacovigilance study.

BMC Pharmacol Toxicol 2018 04 16;19(1):16. Epub 2018 Apr 16.

Department of Neurosciences, Psychology, Drug Research and Child Health, Section of Pharmacology and Toxicology, University of Florence, viale G. Pieraccini, 6, 50139, Florence, Italy.

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https://bmcpharmacoltoxicol.biomedcentral.com/articles/10.11
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http://dx.doi.org/10.1186/s40360-018-0207-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5902928PMC
April 2018

Pomegranate By-Products in Colorectal Cancer Chemoprevention: Effects in Apc-Mutated Pirc Rats and Mechanistic Studies In Vitro and Ex Vivo.

Mol Nutr Food Res 2018 01 22;62(2). Epub 2017 Nov 22.

NEUROFARBA Department, Pharmacology and Toxicology Section, University of Florence, Florence, Italy.

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http://dx.doi.org/10.1002/mnfr.201700401DOI Listing
January 2018

Aging related changes in circulating reactive oxygen species (ROS) and protein carbonyls are indicative of liver oxidative injury.

Toxicol Rep 2018 21;5:141-145. Epub 2017 Dec 21.

Department of NEUROFARBA, Section of Pharmacology and Toxicology, University of Florence, Viale Pieraccini 6, 50139, Florence, Italy.

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http://dx.doi.org/10.1016/j.toxrep.2017.12.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5977162PMC
December 2017

Modulation of the Senescence-Associated Inflammatory Phenotype in Human Fibroblasts by Olive Phenols.

Int J Mol Sci 2017 Oct 30;18(11). Epub 2017 Oct 30.

NEUROFARBA Department, Pharmacology and Toxicology Section, University of Florence, Viale Pieraccini 6, 50139 Florence, Italy.

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http://dx.doi.org/10.3390/ijms18112275DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5713245PMC
October 2017

Chronic Resveratrol Treatment Inhibits MRC5 Fibroblast SASP-Related Protumoral Effects on Melanoma Cells.

J Gerontol A Biol Sci Med Sci 2017 Sep;72(9):1187-1195

Department of Experimental and Clinical Biomedical Science, Section of Experimental Pathology and Oncology, University of Florence, Italy.

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http://academic.oup.com/biomedgerontology/article/72/9/1187/
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http://dx.doi.org/10.1093/gerona/glw336DOI Listing
September 2017

A nutrigenomics approach for the study of anti-aging interventions: olive oil phenols and the modulation of gene and microRNA expression profiles in mouse brain.

Eur J Nutr 2017 Mar 22;56(2):865-877. Epub 2015 Dec 22.

Section of Pharmacology and Toxicology, Department of Neuroscience, Psychology, Drug Research and Child Health (NEUROFARBA), University of Florence, Viale Pieraccini 6, 50139, Florence, Italy.

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http://dx.doi.org/10.1007/s00394-015-1134-4DOI Listing
March 2017

Nutrigenomics of extra-virgin olive oil: A review.

Biofactors 2017 Jan 1;43(1):17-41. Epub 2016 Sep 1.

Department of Pharmaceutical Sciences, Nutrition and Clinical Biochemistry Lab, University of Perugia, Italy.

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http://dx.doi.org/10.1002/biof.1318DOI Listing
January 2017

Serpin A1 C-Terminal Peptides as Collagen Turnover Modulators.

ChemMedChem 2016 08 30;11(16):1850-5. Epub 2015 Nov 30.

Laboratory of Peptide and Protein Chemistry & Biology, Department of NeuroFarBa, Section of Pharmaceutical Sciences and Nutraceutics, University of Florence, via Ugo Schiff 6, 50019, Sesto Fiorentino, Italy.

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http://dx.doi.org/10.1002/cmdc.201500472DOI Listing
August 2016

Long-term Neuroglial Cocultures as a Brain Aging Model: Hallmarks of Senescence, MicroRNA Expression Profiles, and Comparison With In Vivo Models.

J Gerontol A Biol Sci Med Sci 2016 Jan 7;71(1):50-60. Epub 2015 Jan 7.

Department of Neuroscience, Psychology, Drug Research and Child Health (NEUROFARBA), Section of Pharmacology and Toxicology and.

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https://academic.oup.com/biomedgerontology/article-lookup/do
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http://dx.doi.org/10.1093/gerona/glu231DOI Listing
January 2016

Chronic resveratrol treatment ameliorates cell adhesion and mitigates the inflammatory phenotype in senescent human fibroblasts.

J Gerontol A Biol Sci Med Sci 2013 Apr 29;68(4):371-81. Epub 2012 Aug 29.

Department of Preclinical and Clinical Pharmacology, University of Florence, Italy.

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http://dx.doi.org/10.1093/gerona/gls183DOI Listing
April 2013

Long-term dietary extra-virgin olive oil rich in polyphenols reverses age-related dysfunctions in motor coordination and contextual memory in mice: role of oxidative stress.

Rejuvenation Res 2012 Dec 16;15(6):601-12. Epub 2012 Nov 16.

Department of Preclinical and Clinical Pharmacology, University of Florence, 50139 Florence, Italy.

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http://dx.doi.org/10.1089/rej.2012.1346DOI Listing
December 2012

Protective effects of resveratrol against senescence-associated changes in cultured human fibroblasts.

J Gerontol A Biol Sci Med Sci 2011 Jan 24;66(1):9-18. Epub 2010 Sep 24.

Department of Preclinical and Clinical Pharmacology, University of Florence, Italy.

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https://academic.oup.com/biomedgerontology/article-lookup/do
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http://dx.doi.org/10.1093/gerona/glq161DOI Listing
January 2011

Dietary extra-virgin olive oil rich in phenolic antioxidants and the aging process: long-term effects in the rat.

J Nutr Biochem 2010 Apr 14;21(4):290-6. Epub 2009 Apr 14.

Department of Preclinical and Clinical Pharmacology, University of Florence, Florence, Italy.

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http://dx.doi.org/10.1016/j.jnutbio.2008.12.014DOI Listing
April 2010

Environmental ozone exposure and oxidative DNA damage in adult residents of Florence, Italy.

Environ Pollut 2009 May 26;157(5):1521-5. Epub 2008 Oct 26.

Molecular and Nutritional Epidemiology Unit, Cancer Prevention and Research Institute (ISPO), Via Cosimo il Vecchio 2, 50139 Florence, Italy.

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http://dx.doi.org/10.1016/j.envpol.2008.09.011DOI Listing
May 2009

The comet assay: topical issues.

Mutagenesis 2008 May 17;23(3):143-51. Epub 2008 Feb 17.

Department of Nutrition, Faculty of Medicine, University of Oslo, Oslo, Norway.

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http://dx.doi.org/10.1093/mutage/gem051DOI Listing
May 2008

Liver and colon DNA oxidative damage and gene expression profiles of rats fed Arabidopsis thaliana mutant seeds containing contrasted flavonoids.

Food Chem Toxicol 2008 Apr 18;46(4):1213-20. Epub 2007 Oct 18.

Department of Preclinical and Clinical Pharmacology, University of Florence, Viale Pieraccini 6, 50139 Florence, Italy.

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http://dx.doi.org/10.1016/j.fct.2007.10.007DOI Listing
April 2008

Oxidative DNA damage and plasma antioxidant capacity in type 2 diabetic patients with good and poor glycaemic control.

Mutat Res 2008 Feb 14;638(1-2):98-102. Epub 2007 Sep 14.

Department of Pharmacology, University of Florence, Viale Pieraccini 6, 50139 Florence, Italy.

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https://linkinghub.elsevier.com/retrieve/pii/S00275107070034
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http://dx.doi.org/10.1016/j.mrfmmm.2007.09.002DOI Listing
February 2008

Calibration of the comet assay for the measurement of DNA damage in mammalian cells.

Free Radic Res 2006 Nov;40(11):1149-54

Department of Preclinical and Clinical Pharmacology, University of Florence, Florence, Italy.

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http://dx.doi.org/10.1080/10715760600863116DOI Listing
November 2006

Seasonal variations of DNA damage in human lymphocytes: correlation with different environmental variables.

Mutat Res 2006 Jan 10;593(1-2):143-52. Epub 2005 Aug 10.

Dipartimento di Farmacologia Preclinica e Clinica, Università di Firenze, Viale Pieraccini 6, 50139 Firenze, Italy.

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http://dx.doi.org/10.1016/j.mrfmmm.2005.07.002DOI Listing
January 2006

The comet assay approach to senescent human diploid fibroblasts identifies different phenotypes and clarifies relationships among nuclear size, DNA content, and DNA damage.

J Gerontol A Biol Sci Med Sci 2005 Jun;60(6):695-701

Department of Experimental Pathology and Oncology, Viale G.B. Morgagni 50, 50134 Firenze, Italy.

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http://dx.doi.org/10.1093/gerona/60.6.695DOI Listing
June 2005

FGF2-mediated upregulation of urokinase-type plasminogen activator expression requires a MAP-kinase dependent activation of poly(ADP-ribose) polymerase.

J Cell Physiol 2005 Jan;202(1):125-34

Department of Experimental Pathology and Oncology, University of Florence, Italy.

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http://dx.doi.org/10.1002/jcp.20096DOI Listing
January 2005

Increased oxidative DNA damage in mononuclear leukocytes in vitiligo.

Mutat Res 2004 Nov;556(1-2):101-6

Department of Preclinical and Clinical Pharmacology, University of Florence, Viale Pieraccini 6, 50139 Firenze, Florence, Italy.

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http://dx.doi.org/10.1016/j.mrfmmm.2004.07.005DOI Listing
November 2004

Oxidative DNA damage in peripheral blood cells in type 2 diabetes mellitus: higher vulnerability of polymorphonuclear leukocytes.

Mutat Res 2003 Aug;529(1-2):129-33

Department of Preclinical and Clinical Pharmacology, University of Florence, Viale Pieraccini 6, 50139 Florence, Italy.

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http://dx.doi.org/10.1016/s0027-5107(03)00114-3DOI Listing
August 2003

Measurement of DNA breaks and oxidative damage in polymorphonuclear and mononuclear white blood cells: a novel approach using the comet assay.

Mutat Res 2003 Jul;538(1-2):71-80

Dipartimento di Farmacologia Preclinica e Clinica, Università di Firenze, Italy.

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http://dx.doi.org/10.1016/s1383-5718(03)00090-1DOI Listing
July 2003

Effect of 4-coumaric and 3,4-dihydroxybenzoic acid on oxidative DNA damage in rat colonic mucosa.

Br J Nutr 2003 May;89(5):581-7

Department of Pharmacology, University of Florence, viale Pieraccini 6, 50139 Florence, Italy.

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http://dx.doi.org/10.1079/BJN2003849DOI Listing
May 2003

Vulnerability to DNA damage in the aging rat substantia nigra: a study with the comet assay.

Brain Res 2003 Apr;969(1-2):244-7

Department of Pharmacology, University of Florence, Florence, Italy.

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http://dx.doi.org/10.1016/s0006-8993(03)02275-3DOI Listing
April 2003

Effect of N-acetyl-L-cysteine on peroxynitrite and superoxide anion production of lung alveolar macrophages in systemic sclerosis.

Nitric Oxide 2002 Dec;7(4):277-82

Department of Preclinical and Clinical Pharmacology, University of Florence, Viale Pieraccini 6, 50139, Firenze, Italy.

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December 2002

Comet assay as a novel approach for studying DNA damage in focal cerebral ischemia: differential effects of NMDA receptor antagonists and poly(ADP-ribose) polymerase inhibitors.

J Cereb Blood Flow Metab 2002 Jun;22(6):697-704

Department of Preclinical and Clinical Pharmacology, University of Florence, Florence, Italy.

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http://dx.doi.org/10.1097/00004647-200206000-00008DOI Listing
June 2002