Lisa G Horvath

Lisa G Horvath

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Lisa G Horvath

Lisa G Horvath

Publications by authors named "Lisa G Horvath"

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E6AP Promotes a Metastatic Phenotype in Prostate Cancer.

iScience 2019 Nov 2;22:1-15. Epub 2019 Nov 2.

Tumour Suppression Laboratory, Peter MacCallum Cancer Centre, 305 Grattan St, Melbourne, VIC 3000, Australia; Department of Pathology, Peter MacCallum Cancer Centre, Melbourne 3000, Australia; Department of Clinical Pathology, University of Melbourne, Parkville, VIC 3010, Australia; Department of Biochemistry and Molecular Biology, Monash University, Melbourne 3800, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.isci.2019.10.065DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6864340PMC
November 2019

Enzalutamide with Standard First-Line Therapy in Metastatic Prostate Cancer.

N Engl J Med 2019 07 2;381(2):121-131. Epub 2019 Jun 2.

From Monash University (I.D.D., M.F., D.W.P.), Eastern Health (I.D.D.), Australian Urology Associates (M.F.), Monash Health (D.W.P.), and the Peter MacCallum Cancer Centre and the University of Melbourne (S.K.S., S.G.W.), Melbourne, VIC, the National Health and Medical Research Council Clinical Trials Centre, University of Sydney (A.J.M., M.R.S., X.C., W.E.H., E.T., S.Y., A.Y.Z.), the Chris O'Brien Lifehouse (M.R.S., L.G.H., A.Y.Z.), the University of Sydney (L.G.H., G.M.), Royal Prince Alfred Hospital (L.G.H.), Kinghorn Cancer Centre, St. Vincent's Hospital, and Garvan Institute of Medical Research (A.M.J.), Macquarie University (A.Y.Z.), and Western Sydney University (R.R.Z.), Sydney, Concord Cancer Centre, Concord Repatriation General Hospital, Concord, NSW (M.R.S.), Port Macquarie Base Hospital and Mid North Coast Cancer Institute Port Macquarie, Port Macquarie, NSW (S.B.), Sydney Adventist Hospital, Wahroonga, NSW (G.M.), the ANZUP Cancer Trials Group, Camperdown, NSW (M.M.), the Adelaide Cancer Centre and the University of Adelaide (F.P.) and the Royal Adelaide Hospital (T.H.T.), Adelaide, SA, and Orange Health Service, Central West Cancer Care Centre, Orange, NSW (R.R.Z.) - all in Australia; BC Cancer and the University of British Columbia, Vancouver (K.N.C.), the Cross Cancer Institute and the University of Alberta, Edmonton (S.A.N.), Canadian Cancer Trials Group, Queen's University (W.P., F.V.-B.), and the Kingston Health Sciences Center (F.V.-B.), Kingston, ON, and the University of Ottawa and the Ottawa Hospital Research Institute, Ottawa (M.N.R.) - all in Canada; Guy's and St. Thomas' NHS Foundation Trust Biomedical Research Centre, Cancer Research UK and King's College London, and Sarah Cannon Research UK, London (S.C.), and the Royal Cornwall Hospital, Truro (A. Thomson) - all in the United Kingdom; Auckland City Hospital, Auckland (N.J.L.), and the Waikato District Health Board, Hamilton (A. Tan) - both in New Zealand; Cancer Trials Ireland (J.M., R.M.), Mater Misericordiae University Hospital (J.M.), and St. Vincent's University Hospital and University College Dublin (R.M.D.) - all in Dublin; and Dana-Farber Cancer Institute and Harvard Medical School (C.J.S.) - both in Boston.

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http://dx.doi.org/10.1056/NEJMoa1903835DOI Listing
July 2019

Quantification of Small Fiber Neuropathy in Chemotherapy-Treated Patients.

J Pain 2019 Jul 17. Epub 2019 Jul 17.

Brain and Mind Centre, Faculty of Medicine and Health, The University of Sydney, Camperdown, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.jpain.2019.06.011DOI Listing
July 2019

Prognostic Utility of a Whole-blood Androgen Receptor-based Gene Signature in Metastatic Castration-resistant Prostate Cancer.

Eur Urol Focus 2019 May 15. Epub 2019 May 15.

Department of Medicine, School of Clinical Sciences, Monash University, Melbourne, VIC, Australia; Department of Medical Oncology, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia; Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, VIC, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.euf.2019.04.020DOI Listing
May 2019

Extracellular Fatty Acids Are the Major Contributor to Lipid Synthesis in Prostate Cancer.

Mol Cancer Res 2019 04 15;17(4):949-962. Epub 2019 Jan 15.

Discipline of Physiology, School of Medical Sciences & Bosch Institute, Charles Perkins Centre, Faculty of Medicine and Health, The University of Sydney, New South Wales, Australia.

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http://dx.doi.org/10.1158/1541-7786.MCR-18-0347DOI Listing
April 2019

Characterization of the ERG-regulated Kinome in Prostate Cancer Identifies TNIK as a Potential Therapeutic Target.

Neoplasia 2019 04 20;21(4):389-400. Epub 2019 Mar 20.

Cancer Program, Biomedicine Discovery Institute, Monash University, Victoria, Australia; Department of Biochemistry and Molecular Biology, Monash University, Victoria, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.neo.2019.02.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6426874PMC
April 2019

Effect of FAK inhibitor VS-6063 (defactinib) on docetaxel efficacy in prostate cancer.

Prostate 2018 03 5;78(4):308-317. Epub 2018 Jan 5.

Signalling Network Laboratory, Department of Biochemistry and Molecular Biology, Monash University, Clayton, Victoria, Australia.

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http://dx.doi.org/10.1002/pros.23476DOI Listing
March 2018

Altered mitochondrial genome content signals worse pathology and prognosis in prostate cancer.

Prostate 2018 Jan 14;78(1):25-31. Epub 2017 Nov 14.

Laboratory for Human Comparative and Prostate Cancer Genomics, Genomics and Epigenetics Division, Garvan Institute of Medical Research, Darlinghurst, New South Wales, Australia.

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http://dx.doi.org/10.1002/pros.23440DOI Listing
January 2018

Discovering cancer vulnerabilities using high-throughput micro-RNA screening.

Nucleic Acids Res 2017 Dec;45(22):12657-12670

The Kinghorn Cancer Centre & Cancer Research Division, Garvan Institute of Medical Research, Darlinghurst, NSW 2010, Australia.

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http://dx.doi.org/10.1093/nar/gkx1072DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5728403PMC
December 2017

Predictive value of the 2014 International Society of Urological Pathology grading system for prostate cancer in patients undergoing radical prostatectomy with long-term follow-up.

BJU Int 2017 11 30;120(5):651-658. Epub 2017 Apr 30.

Cancer Research Program, Kinghorn Cancer Centre/Garvan Institute of Medical Research, Darlinghurst, NSW, Australia.

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http://dx.doi.org/10.1111/bju.13857DOI Listing
November 2017

Phase 2 study of circulating microRNA biomarkers in castration-resistant prostate cancer.

Br J Cancer 2017 Apr 9;116(8):1002-1011. Epub 2017 Mar 9.

Cancer Division, The Kinghorn Cancer Centre/Garvan Institute of Medical Research, Darlinghurst, New South Wales 2010, Australia.

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http://dx.doi.org/10.1038/bjc.2017.50DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5396108PMC
April 2017

EGFR-Co-Mutated Advanced NSCLC and Response to EGFR Tyrosine Kinase Inhibitors.

J Thorac Oncol 2017 03 14;12(3):585-590. Epub 2016 Sep 14.

Sydney Medical School, University of Sydney, Sydney, New South Wales, Australia; Department of Medical Oncology, Chris O'Brien Lifehouse, Camperdown, New South Wales, Australia.

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http://dx.doi.org/10.1016/j.jtho.2016.09.001DOI Listing
March 2017

Loss of AZGP1 as a Superior Predictor of Relapse in Margin-Positive Localized Prostate Cancer.

Prostate 2016 12 30;76(16):1491-1500. Epub 2016 Jul 30.

Division of Cancer Research, Garvan Institute of Medical Research/The Kinghorn Cancer Centre, Darlinghurst, New South Wales, Australia.

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http://dx.doi.org/10.1002/pros.23233DOI Listing
December 2016

Mutational load of the mitochondrial genome predicts pathological features and biochemical recurrence in prostate cancer.

Aging (Albany NY) 2016 10;8(11):2702-2712

Laboratory for Human Comparative and Prostate Cancer Genomics, Genomics and Epigenetics Division, Garvan Institute of Medical Research, Darlinghurst, NSW 2010, Australia.

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http://dx.doi.org/10.18632/aging.101044DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5191864PMC
October 2016

Resolution of Novel Pancreatic Ductal Adenocarcinoma Subtypes by Global Phosphotyrosine Profiling.

Mol Cell Proteomics 2016 08 3;15(8):2671-85. Epub 2016 Jun 3.

¶Cancer Program, Biomedicine Discovery Institute and Department of Biochemistry and Molecular Biology, Level 1, Building 77, Monash University, VIC 3800, Australia;

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http://dx.doi.org/10.1074/mcp.M116.058313DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4974343PMC
August 2016

CMRF-56(+) blood dendritic cells loaded with mRNA induce effective antigen-specific cytotoxic T-lymphocyte responses.

Oncoimmunology 2016 Jun 5;5(6):e1168555. Epub 2016 May 5.

ANZAC Research Institute, Concord, NSW, Australia; Sydney Medical School, University of Sydney, Camperdown, NSW, Australia; Department of Haematology, Royal Prince Alfred Hospital, Camperdown, NSW, Australia; Department of Haematology, Concord Repatriation General Hospital, Concord, NSW, Australia.

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http://dx.doi.org/10.1080/2162402X.2016.1168555DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4938320PMC
June 2016

Second-line treatment in inoperable pancreatic adenocarcinoma: A systematic review and synthesis of all clinical trials.

Crit Rev Oncol Hematol 2015 Dec 26;96(3):483-97. Epub 2015 Jul 26.

Department of Medical Oncology, The Canberra Hospital, Garran, ACT, Australia; ANU Medical School, Australian National University, Acton, ACT, Australia.

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http://dx.doi.org/10.1016/j.critrevonc.2015.07.007DOI Listing
December 2015

Extraprostatic extension (EPE) of prostatic carcinoma: is its proximity to the surgical margin or Gleason score important?

BJU Int 2015 Sep 15;116(3):343-50. Epub 2014 Dec 15.

Department of Tissue Pathology and Diagnostic Oncology, Royal Prince Alfred Hospital, Sydney, NSW, Australia.

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http://dx.doi.org/10.1111/bju.12911DOI Listing
September 2015

PD-L1 expression is a favorable prognostic factor in early stage non-small cell carcinoma.

Lung Cancer 2015 Aug 18;89(2):181-8. Epub 2015 May 18.

Tissue Pathology and Diagnostic Oncology, Royal Prince Alfred Hospital, Camperdown, NSW, Australia; Sydney Medical School, University of Sydney, Sydney, NSW, Australia; Melanoma Institute Australia, Sydney, NSW, Australia.

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http://dx.doi.org/10.1016/j.lungcan.2015.05.007DOI Listing
August 2015

FAK signaling in human cancer as a target for therapeutics.

Pharmacol Ther 2015 Feb 12;146:132-49. Epub 2014 Oct 12.

St. Vincent's Clinical School, Faculty of Medicine, University of New South Wales, St. Vincent's Hospital, Darlinghurst, NSW 2010, Australia; Department of Biochemistry and Molecular Biology, Faculty of Biomedical and Psychological Sciences, Monash University, Clayton, VIC 3800, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.pharmthera.2014.10.001DOI Listing
February 2015

ERG induces taxane resistance in castration-resistant prostate cancer.

Nat Commun 2014 Nov 25;5:5548. Epub 2014 Nov 25.

1] Institute of Precision Medicine of Weill Cornell Medical College and New York-Presbyterian Hospital, New York, New York 10065, USA [2] Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, New York 10065, USA [3] Weill Cornell Cancer Center, New York, New York 10065, USA.

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http://dx.doi.org/10.1038/ncomms6548DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4244604PMC
November 2014

Expression of phosphorylated-mTOR during the development of prostate cancer.

Prostate 2014 Sep 7;74(12):1231-9. Epub 2014 Jul 7.

Department of Medical Oncology, Chris O'Brien Lifehouse, Sydney, New South Wales, Australia; Department of Medical Oncology, Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia; Sydney Medical School, University of Sydney, Sydney, New South Wales, Australia.

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http://dx.doi.org/10.1002/pros.22840DOI Listing
September 2014

Phosphoproteomic profiling identifies focal adhesion kinase as a mediator of docetaxel resistance in castrate-resistant prostate cancer.

Mol Cancer Ther 2014 Jan 5;13(1):190-201. Epub 2013 Nov 5.

Corresponding Author: Roger J. Daly, Department of Biochemistry and Molecular Biology, School of Biomedical Sciences, Level 1, Building 77, Monash University, VIC 3800, Australia. Telephone: 61-3-990-29301;

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http://dx.doi.org/10.1158/1535-7163.MCT-13-0225-TDOI Listing
January 2014

Patterns of DNA mutations and ALK rearrangement in resected node negative lung adenocarcinoma.

J Thorac Oncol 2013 Apr;8(4):408-14

Department of Medical Oncology, Sydney Cancer Centre, Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia.

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http://dx.doi.org/10.1097/JTO.0b013e318283558eDOI Listing
April 2013

Posterior reversible encephalopathy syndrome following chemotherapy with oxaliplatin and a fluoropyrimidine: a case report and literature review.

Asia Pac J Clin Oncol 2012 Jun;8(2):115-22

University of Sydney, Royal Prince Alfred Hospital, Department of Neurology, New South Wales, Australia.

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http://dx.doi.org/10.1111/j.1743-7563.2012.01544.xDOI Listing
June 2012

Low AZGP1 expression predicts for recurrence in margin-positive, localized prostate cancer.

Prostate 2011 Nov 22;71(15):1638-45. Epub 2011 Mar 22.

Department of Medical Oncology, Sydney Cancer Centre, Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia.

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http://dx.doi.org/10.1002/pros.21381DOI Listing
November 2011

Pathways of chemotherapy resistance in castration-resistant prostate cancer.

Endocr Relat Cancer 2011 Aug 4;18(4):R103-23. Epub 2011 Jul 4.

Department of Medical Oncology, Sydney Cancer Centre, Missenden Road, Camperdown, New South Wales 2050, Australia.

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http://dx.doi.org/10.1530/ERC-10-0343DOI Listing
August 2011

Second opinions in oncology: the experiences of patients attending the Sydney Cancer Centre.

Med J Aust 2009 Aug;191(4):209-12

Department of Cancer Medicine, Centre for Medical Psychology and Evidence-based Decision-making, Central Clinical School, University of Sydney, Sydney, NSW, Australia.

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August 2009

Zinc-alpha2-glycoprotein expression as a predictor of metastatic prostate cancer following radical prostatectomy.

J Natl Cancer Inst 2006 Oct;98(19):1420-4

Cancer Research Program, Garvan Institute of Medical Research, St Vincent's Hospital, Sydney, NSW 2010, Australia.

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http://dx.doi.org/10.1093/jnci/djj378DOI Listing
October 2006

Lymphatic vessel density and lymph node metastasis in prostate cancer.

Prostate 2005 Nov;65(3):222-30

Bernard O'Brien Institute of Microsurgery, Melbourne, Australia.

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http://doi.wiley.com/10.1002/pros.20288
Publisher Site
http://dx.doi.org/10.1002/pros.20288DOI Listing
November 2005

Loss of BMP2, Smad8, and Smad4 expression in prostate cancer progression.

Prostate 2004 May;59(3):234-42

Cancer Research Program, Garvan Institute of Medical Research, St. Vincent's Hospital, Darlinghurst, Sydney, NSW, Australia.

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http://dx.doi.org/10.1002/pros.10361DOI Listing
May 2004