Publications by authors named "Linya You"

16Publications

A pilot study on the use of cerebrospinal fluid cell-free DNA in intramedullary spinal ependymoma.

Authors:
Ian David Connolly Yingmei Li Wenying Pan Eli Johnson Linya You Hannes Vogel John Ratliff Melanie Hayden Gephart

J Neurooncol 2017 Oct 12;135(1):29-36. Epub 2017 Sep 12.

Department of Neurosurgery, Stanford University School of Medicine, 300 Pasteur Drive MC 5327, Stanford, CA, 94305, USA.

View Article and Find Full Text PDF
October 2017

Mice lacking α-tubulin acetyltransferase 1 are viable but display α-tubulin acetylation deficiency and dentate gyrus distortion.

Authors:
Go-Woon Kim Lin Li Mohammad Ghorbani Linya You Xiang-Jiao Yang

J Biol Chem 2016 11;291(48):25279

View Article and Find Full Text PDF
November 2016

BRPF1 is essential for development of fetal hematopoietic stem cells.

Authors:
Linya You Lin Li Jinfeng Zou Kezhi Yan Jad Belle Anastasia Nijnik Edwin Wang Xiang-Jiao Yang

J Clin Invest 2016 09 8;126(9):3247-62. Epub 2016 Aug 8.

View Article and Find Full Text PDF
September 2016

The Chromatin Regulator BRPF3 Preferentially Activates the HBO1 Acetyltransferase but Is Dispensable for Mouse Development and Survival.

Authors:
Kezhi Yan Linya You Cindy Degerny Mohammad Ghorbani Xin Liu Lulu Chen Lin Li Dengshun Miao Xiang-Jiao Yang

J Biol Chem 2016 Feb 16;291(6):2647-63. Epub 2015 Dec 16.

From the Rosalind and Morris Goodman Cancer Research Center, Departments of Biochemistry and Medicine, McGill University, Montreal, Quebec H3A 1A3, Canada, the McGill University Health Center, Montreal, Quebec H3A 1A3, Canada

View Article and Find Full Text PDF
February 2016

Correction: The Lysine Acetyltransferase Activator Brpf1 Governs Dentate Gyrus Development through Neural Stem Cells and Progenitors.

Authors:
Linya You Kezhi Yan Jinfeng Zou Hong Zhao Nicholas R Bertos Morag Park Edwin Wang Xiang-Jiao Yang

PLoS Genet 2015 Jun 15;11(6):e1005329. Epub 2015 Jun 15.

View Article and Find Full Text PDF
June 2015

The chromatin regulator Brpf1 regulates embryo development and cell proliferation.

Authors:
Linya You Kezhi Yan Jinfeng Zou Hong Zhao Nicholas R Bertos Morag Park Edwin Wang Xiang-Jiao Yang

J Biol Chem 2015 May 15;290(18):11349-64. Epub 2015 Mar 15.

From the The Rosalind and Morris Goodman Cancer Research Center, Department of Medicine, and Department of Biochemistry, McGill University, Montreal, Quebec H3A 1A3, McGill University Health Center, Montreal, Quebec H3A 1A3, Canada

View Article and Find Full Text PDF
May 2015

The lysine acetyltransferase activator Brpf1 governs dentate gyrus development through neural stem cells and progenitors.

Authors:
Linya You Kezhi Yan Jinfeng Zou Jinfeng Zhou Hong Zhao Nicholas R Bertos Morag Park Edwin Wang Xiang-Jiao Yang

PLoS Genet 2015 Mar 10;11(3):e1005034. Epub 2015 Mar 10.

The Rosalind & Morris Goodman Cancer Research Center, McGill University, Montreal, Quebec, Canada; Department of Medicine, McGill University, Montreal, Quebec, Canada; Department of Biochemistry, McGill University, Montreal, Quebec, Canada; McGill University Health Center, Montreal, Quebec, Canada.

View Article and Find Full Text PDF
March 2015

Ankyrin repeats of ANKRA2 recognize a PxLPxL motif on the 3M syndrome protein CCDC8.

Authors:
Jianyun Nie Chao Xu Jing Jin Juliette A Aka Wolfram Tempel Vivian Nguyen Linya You Ryan Weist Jinrong Min Tony Pawson Xiang-Jiao Yang

Structure 2015 Apr 5;23(4):700-12. Epub 2015 Mar 5.

The Rosalind & Morris Goodman Cancer Research Center, Department of Medicine, McGill University, Montréal, QC H3A 1A3, Canada; Department of Biochemistry, McGill University, Montréal, QC H3A 1A3, Canada; McGill University Health Center, Montréal, QC H3A 1A3, Canada. Electronic address:

View Article and Find Full Text PDF
April 2015

Deficiency of the chromatin regulator BRPF1 causes abnormal brain development.

Authors:
Linya You Jinfeng Zou Hong Zhao Nicholas R Bertos Morag Park Edwin Wang Xiang-Jiao Yang

J Biol Chem 2015 Mar 7;290(11):7114-29. Epub 2015 Jan 7.

From the Rosalind & Morris Goodman Cancer Research Center, Department of Medicine, McGill University, Quebec H3A 1A3, the Department of Biochemistry, McGill University and McGill University Health Center, Montreal, Quebec H3A 1A3, Canada

View Article and Find Full Text PDF
March 2015

Expression atlas of the multivalent epigenetic regulator Brpf1 and its requirement for survival of mouse embryos.

Authors:
Linya You Lulu Chen Janice Penney Dengshun Miao Xiang-Jiao Yang

Epigenetics 2014 Jun 19;9(6):860-72. Epub 2014 Mar 19.

The Rosalind & Morris Goodman Cancer Research Center; Montreal, QC Canada; Department of Medicine; McGill University; Montreal, QC Canada; Department of Biochemistry; McGill University; Montreal, QC Canada; McGill University Health Center; Montreal, QC Canada.

View Article and Find Full Text PDF
June 2014

Mice lacking α-tubulin acetyltransferase 1 are viable but display α-tubulin acetylation deficiency and dentate gyrus distortion.

Authors:
Go-Woon Kim Lin Li Mohammad Ghorbani Linya You Xiang-Jiao Yang

J Biol Chem 2013 07 28;288(28):20334-50. Epub 2013 May 28.

Rosalind and Morris Goodman Cancer Research Center, Montréal, Québec H3A 1A3, Canada.

View Article and Find Full Text PDF
July 2013

Sumoylation of Krüppel-like factor 4 inhibits pluripotency induction but promotes adipocyte differentiation.

Authors:
Soroush Tahmasebi Mohammad Ghorbani Paul Savage Kezhi Yan Goran Gocevski Lin Xiao Linya You Xiang-Jiao Yang

J Biol Chem 2013 May 20;288(18):12791-804. Epub 2013 Mar 20.

Department of Anatomy and Cell Biology, McGill University Health Center, Montréal, Québec H3A 1A3, Canada.

View Article and Find Full Text PDF
May 2013

The tumor suppressor kinase LKB1 activates the downstream kinases SIK2 and SIK3 to stimulate nuclear export of class IIa histone deacetylases.

Authors:
Donald R Walkinshaw Ryan Weist Go-Woon Kim Linya You Lin Xiao Jianyun Nie Cathy S Li Songping Zhao Minghong Xu Xiang-Jiao Yang

J Biol Chem 2013 Mar 7;288(13):9345-62. Epub 2013 Feb 7.

Rosalind and Morris Goodman Cancer Research Center, McGill University, Montréal, Québec H3A 1A3, Canada.

View Article and Find Full Text PDF
March 2013

Lysine acetylation: enzymes, bromodomains and links to different diseases.

Authors:
Linya You Jianyun Nie Wei-Jian Sun Zhi-Qiang Zheng Xiang-Jiao Yang

Essays Biochem 2012 ;52:1-12

The Rosalind & Morris Goodman Cancer Research Center, McGill University, Montréal, Québec, Canada.

View Article and Find Full Text PDF
October 2012

Sequence-specific recognition of a PxLPxI/L motif by an ankyrin repeat tumbler lock.

Authors:
Chao Xu Jing Jin Chuanbing Bian Robert Lam Ruijun Tian Ryan Weist Linya You Jianyun Nie Alexey Bochkarev Wolfram Tempel Chris S Tan Gregory A Wasney Masoud Vedadi Gerald D Gish Cheryl H Arrowsmith Tony Pawson Xiang-Jiao Yang Jinrong Min

Sci Signal 2012 May 29;5(226):ra39. Epub 2012 May 29.

Structural Genomics Consortium, University of Toronto, 101 College Street, Toronto, Ontario M5G 1L7, Canada.

View Article and Find Full Text PDF
May 2012

Studies on the flavonoid substrates of human UDP-glucuronosyl transferase (UGT) 2B7.

Authors:
Shenggu Xie Linya You Su Zeng

Pharmazie 2007 Aug;62(8):625-9

Department of Pharmaceutical Analysis and Drug Metabolism, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, Zhejiang, People's Republic of China.

View Article and Find Full Text PDF
August 2007