Lino Tessarollo

Lino Tessarollo

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Lino Tessarollo

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Differential Expression of the Transcription Factor GATA3 Specifies Lineage and Functions of Innate Lymphoid Cells.

Immunity 2020 01 24;52(1):83-95.e4. Epub 2019 Dec 24.

Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2019.12.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6962539PMC
January 2020

Assaying Homodimers of NF-κB in Live Single Cells.

Front Immunol 2019 7;10:2609. Epub 2019 Nov 7.

Laboratory of Molecular Biology and Immunology, National Institute on Aging, National Institutes of Health, Baltimore, MD, United States.

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http://dx.doi.org/10.3389/fimmu.2019.02609DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6853996PMC
November 2019

Rbfox1 up-regulation impairs BDNF-dependent hippocampal LTP by dysregulating TrkB isoform expression levels.

Elife 2019 08 20;8. Epub 2019 Aug 20.

Neural Development Section, Mouse Cancer Genetics Program, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, United States.

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http://dx.doi.org/10.7554/eLife.49673DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6715404PMC
August 2019

Regulation of Kit Expression in Early Mouse Embryos and ES Cells.

Stem Cells 2019 03 28;37(3):332-344. Epub 2019 Jan 28.

Dipartimento di Biomedicina e Prevenzione, Università degli Studi di Roma Tor Vergata, Rome, Italy.

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http://dx.doi.org/10.1002/stem.2960DOI Listing
March 2019

The Emergence and Functional Fitness of Memory CD4 T Cells Require the Transcription Factor Thpok.

Immunity 2019 01 9;50(1):91-105.e4. Epub 2019 Jan 9.

Laboratory of Immune Cell Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10747613183056
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http://dx.doi.org/10.1016/j.immuni.2018.12.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6503975PMC
January 2019

Id1 Ablation Protects Hematopoietic Stem Cells from Stress-Induced Exhaustion and Aging.

Cell Stem Cell 2018 Aug 28;23(2):252-265.e8. Epub 2018 Jun 28.

Mouse Cancer Genetics Program, Center for Cancer Research, NCI, Frederick, MD 21702, USA; Basic Science Program and Leidos Biomedical Research Inc., Frederick National Laboratory for Cancer Research, Frederick, MD 21702, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2018.06.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6149219PMC
August 2018

Deletion of the endogenous TrkB.T1 receptor isoform restores the number of hippocampal CA1 parvalbumin-positive neurons and rescues long-term potentiation in pre-symptomatic mSOD1(G93A) ALS mice.

Mol Cell Neurosci 2018 06 24;89:33-41. Epub 2018 Mar 24.

Physiological Science Section, Department of Experimental and Clinical Medicine, University of Florence, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.mcn.2018.03.010DOI Listing
June 2018

POGZ Is Required for Silencing Mouse Embryonic β-like Hemoglobin and Human Fetal Hemoglobin Expression.

Cell Rep 2018 06;23(11):3236-3248

Mouse Cancer Genetics Program, Center for Cancer Research, National Cancer Institute at Frederick, Bldg. 560/12-70, 1050 Boyles Street, Frederick, MD 21702, USA; Basic Research Program, Leidos Biomedical Research Inc., Frederick National Laboratory for Cancer Research, Bldg. 560/32-31D, 1050 Boyles Street, Frederick, MD 21702, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2018.05.043DOI Listing
June 2018

Overexpression of Parkinson's Disease-Associated Mutation LRRK2 G2019S in Mouse Forebrain Induces Behavioral Deficits and α-Synuclein Pathology.

eNeuro 2017 Mar-Apr;4(2). Epub 2017 Mar 17.

Neuroregeneration and Stem Cell Programs, Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205; Soloman H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205; Department of Physiology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205; Adrienne Helis Malvin Medical Research Foundation, New Orleans, Louisiana 70130; Diana Helis Henry Medical Research Foundation, New Orleans, Louisiana 70130.

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http://dx.doi.org/10.1523/ENEURO.0004-17.2017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355896PMC
October 2017

Emi2 Is Essential for Mouse Spermatogenesis.

Cell Rep 2017 07;20(3):697-708

Institute of Molecular and Cell Biology (IMCB), A(∗)STAR (Agency for Science, Technology and Research), 61 Biopolis Drive, Proteos #3-09, Singapore 138673, Republic of Singapore; Department of Biochemistry, National University of Singapore (NUS), Singapore 117597, Republic of Singapore. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2017.06.033DOI Listing
July 2017

Deubiquitinating enzyme VCIP135 dictates the duration of botulinum neurotoxin type A intoxication.

Proc Natl Acad Sci U S A 2017 06 5;114(26):E5158-E5166. Epub 2017 Jun 5.

Laboratory of Protein Dynamics and Signaling, Center for Cancer Research, National Cancer Institute, Frederick, MD 21702;

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http://dx.doi.org/10.1073/pnas.1621076114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5495235PMC
June 2017

Cdk2 catalytic activity is essential for meiotic cell division in vivo.

Biochem J 2016 09 1;473(18):2783-98. Epub 2016 Jul 1.

A*STAR (Agency for Science, Technology and Research), Institute of Molecular and Cell Biology (IMCB), 61 Biopolis Drive, Proteos#3-09, Singapore 138673 Department of Biochemistry, National University of Singapore (NUS), Singapore 117597.

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http://dx.doi.org/10.1042/BCJ20160607DOI Listing
September 2016

A new gain-of-function mouse line to study the role of Wnt3a in development and disease.

Genesis 2016 09 26;54(9):497-502. Epub 2016 Jul 26.

Cancer and Developmental Biology Laboratory, Center for Cancer Research, NCI-Frederick, NIH, Frederick, Maryland, 21702.

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http://dx.doi.org/10.1002/dvg.22959DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6667172PMC
September 2016

Nedd4-2 haploinsufficiency causes hyperactivity and increased sensitivity to inflammatory stimuli.

Sci Rep 2016 09 8;6:32957. Epub 2016 Sep 8.

Neural Development Section, Mouse Cancer Genetics Program, CCR, NCI, Frederick, MD, 21702, USA.

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http://dx.doi.org/10.1038/srep32957DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5015076PMC
September 2016

Interaction with PALB2 Is Essential for Maintenance of Genomic Integrity by BRCA2.

PLoS Genet 2016 08 4;12(8):e1006236. Epub 2016 Aug 4.

Mouse Cancer Genetics Program, Center for Cancer Research, National Cancer Institute, Frederick, Maryland, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1006236DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4973925PMC
August 2016

Impaired Recall of Positional Memory following Chemogenetic Disruption of Place Field Stability.

Cell Rep 2016 07 30;16(3):793-804. Epub 2016 Jun 30.

Department of Neuroscience, Baylor College of Medicine, Houston, TX 77030, USA; Department of Neurology, Baylor College of Medicine, Houston, TX 77030, USA; Department of Neurosurgery, Baylor College of Medicine, Houston, TX 77030, USA; Huffington Center on Aging, Baylor College of Medicine, Houston, TX 77030, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2016.06.032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4956499PMC
July 2016

Fgf3-Fgf4-cis: A new mouse line for studying Fgf functions during mouse development.

Genesis 2016 Feb 14;54(2):91-8. Epub 2016 Jan 14.

Cancer and Developmental Biology Laboratory, National Cancer Institute, Frederick, 21702, Maryland.

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http://dx.doi.org/10.1002/dvg.22913DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6760837PMC
February 2016

DAAM1 and DAAM2 are co-required for myocardial maturation and sarcomere assembly.

Dev Biol 2015 Dec 23;408(1):126-39. Epub 2015 Oct 23.

Department of Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ydbio.2015.10.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4765503PMC
December 2015

Chronic centrosome amplification without tumorigenesis.

Proc Natl Acad Sci U S A 2015 Nov 2;112(46):E6321-30. Epub 2015 Nov 2.

San Diego Branch, Ludwig Institute for Cancer Research, La Jolla, CA 92093; Department of Cellular and Molecular Medicine, University of California at San Diego, La Jolla, CA 92093

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http://dx.doi.org/10.1073/pnas.1519388112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4655534PMC
November 2015

Histone H3 Lysine 27 demethylases Jmjd3 and Utx are required for T-cell differentiation.

Nat Commun 2015 Sep 2;6:8152. Epub 2015 Sep 2.

Laboratory of Immune Cell Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1038/ncomms9152DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4569738PMC
September 2015

BDNF modulates contextual fear learning during adolescence.

Dev Neurosci 2014 1;36(3-4):269-76. Epub 2014 Jul 1.

Department of Psychiatry, Weill Cornell Medical College of Cornell University, New York, N.Y., USA.

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http://dx.doi.org/10.1159/000358824DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150737PMC
April 2015

Folliculin-interacting proteins Fnip1 and Fnip2 play critical roles in kidney tumor suppression in cooperation with Flcn.

Proc Natl Acad Sci U S A 2015 Mar 16;112(13):E1624-31. Epub 2015 Mar 16.

Urologic Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892; Basic Science Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, MD 21702

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http://dx.doi.org/10.1073/pnas.1419502112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4386336PMC
March 2015

Metabolomics reveals a role for the chromatin-binding protein HMGN5 in glutathione metabolism.

PLoS One 2014 2;9(1):e84583. Epub 2014 Jan 2.

Laboratory of Metabolism, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0084583PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3879345PMC
November 2014

Experimental mutagenesis of huntingtin to map cleavage sites: different outcomes in cell and mouse models.

J Huntingtons Dis 2014 ;3(1):73-86

Department of Neuroscience, University of Florida, Gainesville, FL, USA SantaFe HealthCare Alzheimer's Disease Research Center, University of Florida, Gainesville, FL, USA Center for Translational Research in Neurodegenerative Disease, University of Florida, Gainesville, FL, USA McKnight Brain Institute, University of Florida, Gainesville, FL, USA.

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http://dx.doi.org/10.3233/JHD-130087DOI Listing
October 2014

Normal viability of Kai1/Cd82 deficient mice.

Mol Carcinog 2014 Aug 8;53(8):610-24. Epub 2013 Feb 8.

Department of Obstetrics, Gynecology and Reproductive Biology, Michigan State University College of Human Medicine, Grand Rapids, Michigan; Center for Cancer Research, National Cancer Institute, Bethesda, Maryland.

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http://dx.doi.org/10.1002/mc.22009DOI Listing
August 2014

Loss of Cdk2 and cyclin A2 impairs cell proliferation and tumorigenesis.

Cancer Res 2014 Jul 6;74(14):3870-9. Epub 2014 May 6.

Authors' Affiliations: Institute of Molecular and Cell Biology (IMCB), A*STAR (Agency for Science, Technology and Research); Department of Biochemistry, National University of Singapore (NUS), Singapore, Republic of Singapore; and

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http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
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http://dx.doi.org/10.1158/0008-5472.CAN-13-3440DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102624PMC
July 2014

In vivo regulation of NGF-mediated functions by Nedd4-2 ubiquitination of TrkA.

J Neurosci 2014 Apr;34(17):6098-106

Departments of Cell Biology and Pathology, Biochemistry and Molecular Biology, Instituto de Neurociencias de Castilla y León (INCyL), Universidad de Salamanca, Salamanca 37007, Spain, Neural Development Group, Mouse Cancer Genetics Program, Center for Cancer Research, National Cancer Institute, Frederick, Maryland 21702, and Institute of Biomedical Research of Salamanca, Salamanca 37007, Spain.

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http://dx.doi.org/10.1523/JNEUROSCI.4271-13.2014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3996226PMC
April 2014

TrkA in vivo function is negatively regulated by ubiquitination.

J Neurosci 2014 Mar;34(11):4090-8

Neural Development Section, Mouse Cancer Genetics Program, National Cancer Institute, Frederick, Maryland 21702, Department of Target Discovery and Experimental Microbiology, U.S. Army Medical Research Institute of Infectious Diseases, Frederick, Maryland 21702, University of Maryland School of Nursing and Program in Neuroscience, Baltimore, Maryland 21201, and Department of MVIMG, Wexner Medical Center Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio 43210.

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http://dx.doi.org/10.1523/JNEUROSCI.4294-13.2014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3951704PMC
March 2014

Non-Myeloid Cells are Major Contributors to Innate Immune Responses via Production of Monocyte Chemoattractant Protein-1/CCL2.

Front Immunol 2014 Jan 7;4:482. Epub 2014 Jan 7.

Laboratory of Molecular Immunoregulation, Cancer and Inflammation Program, Center for Cancer Research, National Cancer Institute , Frederick, MD , USA.

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http://dx.doi.org/10.3389/fimmu.2013.00482DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3882876PMC
January 2014

Parthanatos mediates AIMP2-activated age-dependent dopaminergic neuronal loss.

Nat Neurosci 2013 Oct 25;16(10):1392-400. Epub 2013 Aug 25.

1] Neuroregeneration and Stem Cell Programs, Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA. [2] Department of Physiology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA. [3] Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA. [4] Adrienne Helis Malvin Medical Research Foundation, New Orleans, Louisiana, USA.

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http://dx.doi.org/10.1038/nn.3500DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3785563PMC
October 2013

RanBPM, a scaffolding protein for gametogenesis.

Curr Top Dev Biol 2013 ;102:357-84

Neural Development Section, Mouse Cancer Genetics Program, Center for Cancer Research, NCI, Frederick, Maryland, USA.

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https://linkinghub.elsevier.com/retrieve/pii/B97801241602480
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http://dx.doi.org/10.1016/B978-0-12-416024-8.00013-1DOI Listing
September 2013

Signal relay by CC chemokine receptor 2 (CCR2) and formylpeptide receptor 2 (Fpr2) in the recruitment of monocyte-derived dendritic cells in allergic airway inflammation.

J Biol Chem 2013 Jun 19;288(23):16262-73. Epub 2013 Apr 19.

Laboratory of Molecular Immunoregulation, Cancer and Inflammation Program, Center for Cancer Research, NCI, National Institutes of Health, Frederick, Maryland 21702, USA.

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http://dx.doi.org/10.1074/jbc.M113.450635DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3675565PMC
June 2013

Chemotherapy-induced bone marrow nerve injury impairs hematopoietic regeneration.

Nat Med 2013 Jun 5;19(6):695-703. Epub 2013 May 5.

Ruth L. and David S. Gottesman Institute for Stem Cell and Regenerative Medicine Research, Albert Einstein College of Medicine, New York, New York, USA.

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http://dx.doi.org/10.1038/nm.3155DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3964478PMC
June 2013

Essential regulation of lung surfactant homeostasis by the orphan G protein-coupled receptor GPR116.

Cell Rep 2013 May 16;3(5):1457-64. Epub 2013 May 16.

Tumor Angiogenesis Section, Mouse Cancer Genetics Program (MCGP), Center for Cancer Research (CCR), National Cancer Institute (NCI), Frederick, MD 21702, USA.

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http://dx.doi.org/10.1016/j.celrep.2013.04.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3695742PMC
May 2013

Musashi1-CreER(T2) : a new cre line for conditional mutagenesis in neural stem cells.

Genesis 2013 Feb 26;51(2):128-34. Epub 2012 Nov 26.

Division of Genomics and Genetics, Institute of Molecular and Cell Biology, Agency for Science, Technology and Research, Singapore.

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http://dx.doi.org/10.1002/dvg.22357DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3577968PMC
February 2013

Midbrain-derived neurotrophins support survival of immature striatal projection neurons.

J Neurosci 2013 Feb;33(8):3363-9

Department of Pharmacology and Physiology, Georgetown University Medical Center, Washington, DC 20057, USA.

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http://dx.doi.org/10.1523/JNEUROSCI.3687-12.2013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3711532PMC
February 2013

Deletion of the BDNF truncated receptor TrkB.T1 delays disease onset in a mouse model of amyotrophic lateral sclerosis.

PLoS One 2012 27;7(6):e39946. Epub 2012 Jun 27.

Neural Development Section, Mouse Cancer Genetics Program, Center for Cancer Research, National Cancer Institute, Frederick, Maryland, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0039946PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3384607PMC
January 2013

Sexually dimorphic BDNF signaling directs sensory innervation of the mammary gland.

Science 2012 Dec;338(6112):1357-60

The Solomon H. Snyder Department of Neuroscience, Howard Hughes Medical Institute, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

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http://www.sciencemag.org/cgi/doi/10.1126/science.1228258
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http://dx.doi.org/10.1126/science.1228258DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3826154PMC
December 2012

TrkB phosphorylation by Cdk5 is required for activity-dependent structural plasticity and spatial memory.

Nat Neurosci 2012 Nov 14;15(11):1506-15. Epub 2012 Oct 14.

Division of Life Science, The Hong Kong University of Science and Technology, Hong Kong, China.

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http://www.nature.com/articles/nn.3237
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http://dx.doi.org/10.1038/nn.3237DOI Listing
November 2012

Cancer-associated epithelial cell adhesion molecule (EpCAM; CD326) enables epidermal Langerhans cell motility and migration in vivo.

Proc Natl Acad Sci U S A 2012 Apr 12;109(15):E889-97. Epub 2012 Mar 12.

Dermatology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.

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http://www.pnas.org/cgi/doi/10.1073/pnas.1117674109
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http://dx.doi.org/10.1073/pnas.1117674109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3326512PMC
April 2012

Cyclin-dependent kinase 1 (Cdk1) is essential for cell division and suppression of DNA re-replication but not for liver regeneration.

Proc Natl Acad Sci U S A 2012 Mar 21;109(10):3826-31. Epub 2012 Feb 21.

Institute of Molecular and Cell Biology, Agency for Science, Technology, and Research (ASTAR), Republic of Singapore 138673.

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http://dx.doi.org/10.1073/pnas.1115201109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3309725PMC
March 2012

Characterization of transgenic mice expressing cancer-associated variants of human NOTCH1.

Genesis 2012 Feb 6;50(2):112-8. Epub 2012 Jan 6.

Department of Anatomy and Cell Biology, Carver College of Medicine, University of Iowa, Iowa City, Iowa 52242, USA.

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http://doi.wiley.com/10.1002/dvg.20798
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http://dx.doi.org/10.1002/dvg.20798DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3682665PMC
February 2012

Tamalin is a critical mediator of electroconvulsive shock-induced adult neuroplasticity.

J Neurosci 2012 Feb;32(7):2252-62

Neural Development Section, Mouse Cancer Genetics Program, Center for Cancer Research, National Cancer Institute, Frederick, Maryland 21702, USA.

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http://www.jneurosci.org/cgi/doi/10.1523/JNEUROSCI.5493-11.2
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http://dx.doi.org/10.1523/JNEUROSCI.5493-11.2012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3780770PMC
February 2012

RanBPM is essential for mouse spermatogenesis and oogenesis.

Development 2011 Jun 11;138(12):2511-21. Epub 2011 May 11.

Neural Development Section, Mouse Cancer Genetics Program, Center for Cancer Research, NCI, Frederick, MD 21702, USA.

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http://dx.doi.org/10.1242/dev.062505DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3100708PMC
June 2011

The cytoskeletal adaptor protein band 4.1B is required for the maintenance of paranodal axoglial septate junctions in myelinated axons.

J Neurosci 2011 Jun;31(22):8013-24

Department of Cell and Molecular Physiology, University of North Carolina Neuroscience Center, and Carolina Center for Developmental Disabilities, University of North Carolina School of Medicine, Chapel Hill, North Carolina 27599, USA.

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http://dx.doi.org/10.1523/JNEUROSCI.1015-11.2011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3121702PMC
June 2011

Embryonic stem cell-derived motoneurons provide a highly sensitive cell culture model for botulinum neurotoxin studies, with implications for high-throughput drug discovery.

Stem Cell Res 2011 May 19;6(3):195-205. Epub 2011 Jan 19.

Department of Target Discovery and Experimental Microbiology, US Army Medical Research Institute of Infectious Diseases, 1425 Porter Street, Frederick, MD 21702-5011, USA.

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http://dx.doi.org/10.1016/j.scr.2011.01.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3081902PMC
May 2011