Lingegowda S Mangala

Lingegowda S Mangala

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Lingegowda S Mangala

Lingegowda S Mangala

Publications by authors named "Lingegowda S Mangala"

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A-to-I-edited miRNA-379-5p inhibits cancer cell proliferation through CD97-induced apoptosis.

J Clin Invest 2019 Nov 4. Epub 2019 Nov 4.

Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.

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http://dx.doi.org/10.1172/JCI123396DOI Listing
November 2019

Identifying and targeting angiogenesis-related microRNAs in ovarian cancer.

Oncogene 2019 Aug 9;38(33):6095-6108. Epub 2019 Jul 9.

Department of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

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http://dx.doi.org/10.1038/s41388-019-0862-yDOI Listing
August 2019

PTGER3 induces ovary tumorigenesis and confers resistance to cisplatin therapy through up-regulation Ras-MAPK/Erk-ETS1-ELK1/CFTR1 axis.

EBioMedicine 2019 Feb 14;40:290-304. Epub 2019 Jan 14.

Department of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Center for RNA Interference and Non-Coding RNA, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2018.11.045DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411965PMC
February 2019

Bone protection by inhibition of microRNA-182.

Nat Commun 2018 10 5;9(1):4108. Epub 2018 Oct 5.

Arthritis and Tissue Degeneration Program, The David Z. Rosensweig Genomics Research Center, Hospital for Special Surgery, New York, 10021, NY, USA.

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http://dx.doi.org/10.1038/s41467-018-06446-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173760PMC
October 2018

ADH1B promotes mesothelial clearance and ovarian cancer infiltration.

Oncotarget 2018 May 18;9(38):25115-25126. Epub 2018 May 18.

Department of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.

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http://dx.doi.org/10.18632/oncotarget.25344DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5982754PMC
May 2018

Chitosan Nanoparticles for miRNA Delivery.

Methods Mol Biol 2017 ;1632:219-230

Center for RNA Interference and Non-coding RNA, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

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http://dx.doi.org/10.1007/978-1-4939-7138-1_14DOI Listing
April 2018

RNA interference-based therapy and its delivery systems.

Cancer Metastasis Rev 2018 03;37(1):107-124

Department of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

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http://dx.doi.org/10.1007/s10555-017-9717-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5898634PMC
March 2018

Cancer-associated fibroblasts regulate endothelial adhesion protein LPP to promote ovarian cancer chemoresistance.

J Clin Invest 2018 02 18;128(2):589-606. Epub 2017 Dec 18.

Department of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.

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http://dx.doi.org/10.1172/JCI95200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5785271PMC
February 2018

Peroxisomes contribute to oxidative stress in neurons during doxorubicin-based chemotherapy.

Mol Cell Neurosci 2018 01 24;86:65-71. Epub 2017 Nov 24.

Department of Neurobiology and Anatomy, The University of Texas, Houston Medical School, Houston, TX, United States; The University of Texas Graduate School of Biomedical Sciences, Houston, TX, United States. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10447431173011
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http://dx.doi.org/10.1016/j.mcn.2017.11.014DOI Listing
January 2018

MYC Targeted Long Noncoding RNA DANCR Promotes Cancer in Part by Reducing p21 Levels.

Cancer Res 2018 01 27;78(1):64-74. Epub 2017 Nov 27.

Abramson Family Cancer Research Institute, Abramson Cancer Center and Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1158/0008-5472.CAN-17-0815DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993051PMC
January 2018

Differential Effects of EGFL6 on Tumor versus Wound Angiogenesis.

Cell Rep 2017 Dec;21(10):2785-2795

Department of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Center for RNA Interference and Non-Coding RNA, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2017.11.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749980PMC
December 2017

Systematic characterization of A-to-I RNA editing hotspots in microRNAs across human cancers.

Genome Res 2017 07 14;27(7):1112-1125. Epub 2017 Apr 14.

Graduate Program in Structural and Computational Biology and Molecular Biophysics, Baylor College of Medicine, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1101/gr.219741.116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5495064PMC
July 2017

Role of CTGF in Sensitivity to Hyperthermia in Ovarian and Uterine Cancers.

Cell Rep 2016 11;17(6):1621-1631

Department of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center (MDACC), Houston, TX 77030, USA; Center for RNA Interference and Non-Coding RNAs, MDACC, Houston, TX 77030, USA; Department of Cancer Biology, MDACC, Houston, TX 77030, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2016.10.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5123842PMC
November 2016

Targeting Stromal Glutamine Synthetase in Tumors Disrupts Tumor Microenvironment-Regulated Cancer Cell Growth.

Cell Metab 2016 11;24(5):685-700

Laboratory for Systems Biology of Human Diseases, Rice University, Houston, TX 77005, USA; Department of Chemical and Biomolecular Engineering, Rice University, Houston, TX 77005, USA; Department of Bioengineering, Rice University, Houston, TX 77005, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2016.10.011DOI Listing
November 2016

Assessment of In Vivo siRNA Delivery in Cancer Mouse Models.

Methods Mol Biol 2016 ;1402:189-197

Department of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center (MDACC), Houston, TX, 77054, USA.

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http://dx.doi.org/10.1007/978-1-4939-3378-5_15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5142631PMC
October 2016

ΔNp63/DGCR8-Dependent MicroRNAs Mediate Therapeutic Efficacy of HDAC Inhibitors in Cancer.

Cancer Cell 2016 06;29(6):874-888

Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA; Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA; Graduate School of Biomedical Sciences, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA; Center for RNA Interference and Non-Coding RNA, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2016.04.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908836PMC
June 2016

Role of Increased n-acetylaspartate Levels in Cancer.

J Natl Cancer Inst 2016 Jan 26;108(6):djv426. Epub 2016 Jan 26.

Departments of Gynecologic Oncology and Reproductive Medicine (BZ, RAP, RR, TM, ASN, HJD, WH, CI, SYW, KMG, SP, LSM, AMN, GAP, AKS), Cancer Systems Imaging (NMZ, CRM, PKB), Biostatistics (MG), Cancer Medicine (CVP), Center for RNA Interference and Non-Coding RNA (CI, LSM, CRA, GLB, AKS), Cancer Biology (YS, MBE, GLB, AKS), Experimental Therapeutics (CRA, GLB), Bioinformatics and Computational Biology (YW, KAB), Melanoma Medical Oncology (MAD), and Pathology (JL), University of Texas M. D. Anderson Cancer Center, Houston, TX; Department of Nanomedicine and Bioengineering, UT Health, Houston, TX (GLB, AKS); Departments of Psychology, Urology, and Obstetrics and Gynecology, the University of Iowa, Iowa City, IA (SKL); Laboratory for Systems Biology of Human Diseases (LY, JB, AA, DN), Department of Chemical and Biomolecular Engineering (LY, JB, AA, DN), and Department of Bioengineering (DN), Rice University, Houston, TX.

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http://dx.doi.org/10.1093/jnci/djv426DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4849357PMC
January 2016

Targeting c-MYC in Platinum-Resistant Ovarian Cancer.

Mol Cancer Ther 2015 Oct 30;14(10):2260-9. Epub 2015 Jul 30.

Department of Biochemistry, University of Puerto Rico, Medical Sciences Campus, San Juan, Puerto Rico. University of Puerto Rico Comprehensive Cancer Center, San Juan, Puerto Rico.

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http://dx.doi.org/10.1158/1535-7163.MCT-14-0801DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4596776PMC
October 2015

Augmentation of response to chemotherapy by microRNA-506 through regulation of RAD51 in serous ovarian cancers.

J Natl Cancer Inst 2015 Jul 20;107(7). Epub 2015 May 20.

: Departments of Pathology (GL, DY, YS, XL, PJ, DC, LH, WZ), Experimental Therapeutics (CRA, GLB), and Gynecologic Oncology and Reproductive Medicine (RR, LSM, AKS), Division of Cancer Medicine (CVP), Center for RNAi and Non-Coding RNA (RR, CVP, LSM, CRA, GLB, AKS, WZ), the University of Texas MD Anderson Cancer Center, Houston, TX; Department of Gynecology and Obstetrics, Tianjin Medical University General Hospital, Tianjin, China (GL, YW, FX); Department of Pathology (YS) and Epidemiology (KC), Tianjin Medical University Cancer Institute and Hospital, Tianjin, China; Department of Biochemistry and Molecular Biology, State Key Laboratory of Cancer Biology, the Fourth Military Medical University, Xi'an, China (XL); Institute for Systems Biology, Seattle, WA (IS); Department of Experimental Oncology and Molecular Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy (LDC, DM).

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http://academic.oup.com/jnci/article/doi/10.1093/jnci/djv108
Publisher Site
http://dx.doi.org/10.1093/jnci/djv108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4554255PMC
July 2015

Immunotherapy targeting folate receptor induces cell death associated with autophagy in ovarian cancer.

Clin Cancer Res 2015 Jan 21;21(2):448-59. Epub 2014 Nov 21.

Department of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas. Department of Systems Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas. Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas.

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http://clincancerres.aacrjournals.org/content/early/2015/01/
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http://clincancerres.aacrjournals.org/content/early/2014/11/
Web Search
http://clincancerres.aacrjournals.org/cgi/doi/10.1158/1078-0
Publisher Site
http://dx.doi.org/10.1158/1078-0432.CCR-14-1578DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4297546PMC
January 2015

Calcium-dependent FAK/CREB/TNNC1 signalling mediates the effect of stromal MFAP5 on ovarian cancer metastatic potential.

Nat Commun 2014 Oct 3;5:5092. Epub 2014 Oct 3.

1] Department of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA [2] The University of Texas Graduate School of Biomedical Sciences at Houston, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1038/ncomms6092DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4185407PMC
October 2014

Hypoxia-mediated downregulation of miRNA biogenesis promotes tumour progression.

Nat Commun 2014 Oct 29;5:5202. Epub 2014 Oct 29.

1] Department of Gynecologic Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, Texas 77030, USA [2] Center for RNA Interference and Non-Coding RNA, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, Texas 77030, USA [3] Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1038/ncomms6202DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4215647PMC
October 2014

miR-34a blocks osteoporosis and bone metastasis by inhibiting osteoclastogenesis and Tgif2.

Nature 2014 Aug 25;512(7515):431-5. Epub 2014 Jun 25.

1] Department of Pharmacology, The University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA [2] Simmons Cancer Center, The University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.

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http://dx.doi.org/10.1038/nature13375DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4149606PMC
August 2014

Hematogenous metastasis of ovarian cancer: rethinking mode of spread.

Cancer Cell 2014 Jul;26(1):77-91

Department of Gynecologic Oncology and Reproductive Medicine, University of Texas M.D. Anderson Cancer Center, Houston, TX 77030, USA; Department of Cancer Biology, University of Texas M.D. Anderson Cancer Center, Houston, TX 77030, USA; Center for RNA Interference and Non-coding RNA, University of Texas M.D. Anderson Cancer Center, Houston, TX 77030, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccr.2014.05.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4100212PMC
July 2014

Notch3 pathway alterations in ovarian cancer.

Cancer Res 2014 Jun 17;74(12):3282-93. Epub 2014 Apr 17.

Authors' Affiliations: Departments of Gynecologic Oncology and Reproductive Medicine, Systems Biology, Pathology, Experimental Therapeutics, Bioinformatics and Computational Biology, Cancer Biology, Thoracic/Head and Neck Medical Oncology, and The Center for RNA Interference and Non-Coding RNA, The University of Texas MD Anderson Cancer Center, Houston, TexasAuthors' Affiliations: Departments of Gynecologic Oncology and Reproductive Medicine, Systems Biology, Pathology, Experimental Therapeutics, Bioinformatics and Computational Biology, Cancer Biology, Thoracic/Head and Neck Medical Oncology, and The Center for RNA Interference and Non-Coding RNA, The University of Texas MD Anderson Cancer Center, Houston, TexasAuthors' Affiliations: Departments of Gynecologic Oncology and Reproductive Medicine, Systems Biology, Pathology, Experimental Therapeutics, Bioinformatics and Computational Biology, Cancer Biology, Thoracic/Head and Neck Medical Oncology, and The Center for RNA Interference and Non-Coding RNA, The University of Texas MD Anderson Cancer Center, Houston, Texas

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http://dx.doi.org/10.1158/0008-5472.CAN-13-2066DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4058356PMC
June 2014

Cell killing and radiosensitizing effects of atorvastatin in PC3 prostate cancer cells.

J Radiat Res 2012 ;53(2):225-33

University of Houston at Clear Lake, Houston, Texas 77058, USA.

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http://dx.doi.org/10.1269/jrr.11114DOI Listing
August 2012

Effects of simulated microgravity on expression profile of microRNA in human lymphoblastoid cells.

J Biol Chem 2011 Sep 20;286(37):32483-90. Epub 2011 Jul 20.

Radiation Biophysics Laboratory, NASA Johnson Space Center, Houston, TX 77058, USA.

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http://dx.doi.org/10.1074/jbc.M111.267765DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3173213PMC
September 2011

Dopamine blocks stress-mediated ovarian carcinoma growth.

Clin Cancer Res 2011 Jun 29;17(11):3649-59. Epub 2011 Apr 29.

Departments of Gynecologic Oncology, Cancer Biology, and Experimental Therapeutics, and Center for RNA Interference and Non-coding RNA, University of Texas MD Anderson Cancer Center, Houston, Texas, USA.

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http://clincancerres.aacrjournals.org/cgi/doi/10.1158/1078-0
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http://dx.doi.org/10.1158/1078-0432.CCR-10-2441DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3107884PMC
June 2011

Targeted gene silencing using RGD-labeled chitosan nanoparticles.

Clin Cancer Res 2010 Aug 10;16(15):3910-22. Epub 2010 Jun 10.

Department of Gynecologic Oncology, University of Texas M.D. Anderson Cancer Center, 1515 Holcombe Blvd., Houston, TX 77030, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-10-0005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2912984PMC
August 2010

Liposomal siRNA for ovarian cancer.

Methods Mol Biol 2009 ;555:29-42

Department of Gynecologic Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, TX, USA.

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http://dx.doi.org/10.1007/978-1-60327-295-7_3DOI Listing
September 2009

Estrous cycle modulates ovarian carcinoma growth.

Clin Cancer Res 2009 May 21;15(9):2971-8. Epub 2009 Apr 21.

Department of Gynecologic Oncology and Cancer Biology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-08-2525DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2743312PMC
May 2009

Tissue transglutaminase: from biological glue to cell survival cues.

Front Biosci 2006 Jan 1;11:173-85. Epub 2006 Jan 1.

Department of Experimental Therapeutics, The University of Texas M.D. Anderson Cancer, Houston, TX 77030, USA.

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http://dx.doi.org/10.2741/1789DOI Listing
January 2006

Tissue transglutaminase-induced alterations in extracellular matrix inhibit tumor invasion.

Mol Cancer 2005 Sep 9;4:33. Epub 2005 Sep 9.

Department of Experimental Therapeutics, The University of Texas M. D. Anderson Cancer Center, Houston, Texas, USA.

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http://dx.doi.org/10.1186/1476-4598-4-33DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1224867PMC
September 2005

Tissue transglutaminase (TG2) in cancer biology.

Prog Exp Tumor Res 2005 ;38:125-38

The University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA.

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http://dx.doi.org/10.1159/000084237DOI Listing
May 2005