Publications by authors named "Lindsey Doyle"

14Publications

Unintended specificity of an engineered ligand-binding protein facilitated by unpredicted plasticity of the protein fold.

Protein Eng Des Sel 2018 10;31(10):375-387

Division of Basic Sciences, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave. N., Seattle, WA, USA.

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October 2018

Structure, subunit organization and behavior of the asymmetric Type IIT restriction endonuclease BbvCI.

Nucleic Acids Res 2019 01;47(1):450-467

Division of Basic Sciences, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave. N., Seattle, WA 98109, USA.

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January 2019

Sampling and energy evaluation challenges in ligand binding protein design.

Protein Sci 2017 Dec 30;26(12):2426-2437. Epub 2017 Oct 30.

Institute for Protein Design, University of Washington, Seattle, Washington.

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December 2017

The effect of increasing numbers of repeats on TAL effector DNA binding specificity.

Nucleic Acids Res 2017 Jun;45(11):6960-6970

Plant Pathology and Plant-Microbe Biology Section, School of Integrative Plant Science, Cornell University, Ithaca, NY 14853, USA.

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June 2017

Rational design of α-helical tandem repeat proteins with closed architectures.

Nature 2015 Dec 16;528(7583):585-8. Epub 2015 Dec 16.

Division of Basic Sciences, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue N., Seattle, Washington 98109, USA.

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December 2015

A synthetic sex ratio distortion system for the control of the human malaria mosquito.

Nat Commun 2014 Jun 10;5:3977. Epub 2014 Jun 10.

1] Department of Life Sciences, Imperial College London, South Kensington Campus, London SW7 2AZ, UK [2] Centro di Genomica Funzionale, University of Perugia, Dipartimento di Medicina Sperimentale Via Gambuli, Edificio D, 3° Piano, 06132 Perugia, Italy [3].

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June 2014

Comprehensive homing endonuclease target site specificity profiling reveals evolutionary constraints and enables genome engineering applications.

Nucleic Acids Res 2012 Mar 25;40(6):2587-98. Epub 2011 Nov 25.

Department of Pathology, University of Washington, Box 357705, Seattle, WA 98195, USA.

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March 2012