Lindsay Burch

Lindsay Burch

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Lindsay Burch

Lindsay Burch

Publications by authors named "Lindsay Burch"

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A single nucleotide polymorphism on exon-4 of the gene encoding PPARdelta is associated with reduced height in adults and children.

J Clin Endocrinol Metab 2009 Jul 21;94(7):2587-93. Epub 2009 Apr 21.

Biomedical Research Institute, Ninewells Hospital, Dundee DD1-9SY, United Kingdom.

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http://dx.doi.org/10.1210/jc.2009-0392DOI Listing
July 2009

Peptide combinatorial libraries identify TSC2 as a death-associated protein kinase (DAPK) death domain-binding protein and reveal a stimulatory role for DAPK in mTORC1 signaling.

J Biol Chem 2009 Jan 30;284(1):334-44. Epub 2008 Oct 30.

Institute of Genetics and Molecular Medicine, CRUK p53 Signal Transduction Laboratories, University of Edinburgh, Edinburgh EH4 2XR, United Kingdom.

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http://dx.doi.org/10.1074/jbc.M805165200DOI Listing
January 2009

Analysis of the collagen I and fibronectin of temporomandibular joint synovial fluid and discs.

J Oral Maxillofac Surg 2009 Jan;67(1):105-13

Department of Oral Diagnostic Sciences, School of Dental Medicine, State University of New York at Buffalo, Buffalo, NY, USA.

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http://dx.doi.org/10.1016/j.joms.2008.08.029DOI Listing
January 2009

DAPK-1 binding to a linear peptide motif in MAP1B stimulates autophagy and membrane blebbing.

J Biol Chem 2008 Apr 14;283(15):9999-10014. Epub 2008 Jan 14.

University of Edinburgh Cancer Centre, Cell Signalling Unit, South Crewe Road, Edinburgh, Scotland, United Kingdom.

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http://dx.doi.org/10.1074/jbc.M706040200DOI Listing
April 2008

Microarray-formatted clinical biomarker assay development using peptide aptamers to anterior gradient-2.

Biochemistry 2007 Dec 10;46(48):13742-51. Epub 2007 Nov 10.

CRUK p53 Signal Transduction Group, Cell Signalling Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XR, United Kingdom.

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http://dx.doi.org/10.1021/bi7008739DOI Listing
December 2007

Phage-peptide display identifies the interferon-responsive, death-activated protein kinase family as a novel modifier of MDM2 and p21WAF1.

J Mol Biol 2004 Mar;337(1):115-28

Cancer Research UK Laboratories, Department of Molecular and Cellular Pathology, University of Dundee, Dundee DD1 9SY, Scotland, UK.

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http://dx.doi.org/10.1016/j.jmb.2003.10.081DOI Listing
March 2004

Expansion of protein interaction maps by phage peptide display using MDM2 as a prototypical conformationally flexible target protein.

J Mol Biol 2004 Mar;337(1):129-45

Cancer Research UK Laboratories, Department of Molecular and Cellular Pathology, The University of Dundee, Dundee DD1 9SY, Scotland, UK.

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http://dx.doi.org/10.1016/j.jmb.2004.01.017DOI Listing
March 2004

The proline repeat domain of p53 binds directly to the transcriptional coactivator p300 and allosterically controls DNA-dependent acetylation of p53.

Mol Cell Biol 2003 Dec;23(23):8846-61

Cancer Research UK Laboratories, P53 Signal Transduction Group, Department of Molecular and Cellular Pathology, University of Dundee, Dundee DD1 9SY, United Kingdom.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC262654PMC
http://dx.doi.org/10.1128/mcb.23.23.8846-8861.2003DOI Listing
December 2003

Allosteric effects mediate CHK2 phosphorylation of the p53 transactivation domain.

EMBO Rep 2003 Aug;4(8):787-92

Department of Molecular and Cellular Pathology, Cancer Research UK Laboratories, University of Dundee, UK.

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http://dx.doi.org/10.1038/sj.embor.embor901DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1326341PMC
August 2003

The conformationally flexible S9-S10 linker region in the core domain of p53 contains a novel MDM2 binding site whose mutation increases ubiquitination of p53 in vivo.

J Biol Chem 2002 Aug 29;277(32):28446-58. Epub 2002 Mar 29.

Department of Molecular and Cellular Pathology, The Cancer Research UK Laboratories, The University of Dundee, Dundee DD1 9SY, Scotland.

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http://dx.doi.org/10.1074/jbc.M202296200DOI Listing
August 2002