Linda W van Laake

Linda W van Laake

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Linda W van Laake

Linda W van Laake

Publications by authors named "Linda W van Laake"

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Vasculature on the clock: Circadian rhythm and vascular dysfunction.

Vascul Pharmacol 2018 09 17;108:1-7. Epub 2018 May 17.

Hatter Institute for Cardiovascular research in Africa and Lionel Opie Preclinical Imaging Core Facility, Faculty of Health Sciences, University of Cape Town, South Africa. Electronic address:

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http://dx.doi.org/10.1016/j.vph.2018.05.003DOI Listing
September 2018

The circadian clock in cardiovascular regulation and disease: Lessons from the Nobel Prize in Physiology or Medicine 2017.

Eur Heart J 2018 Jun;39(24):2326-2329

Division of Cardiovascular Diseases, Department of Medicine, University of Alabama at Birmingham, 703 19th St. S., ZRB 308, Birmingham, Alabama, USA.

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http://dx.doi.org/10.1093/eurheartj/ehx775DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6012474PMC
June 2018

New dimensions in circadian clock function: the role of biological sex.

Cardiovasc Res 2018 Feb;114(2):203-204

Department of Cardiology, Division of Heart and Lungs, and Regenerative Medicine Center, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands.

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http://dx.doi.org/10.1093/cvr/cvx243DOI Listing
February 2018

Circadian clocks: from stem cells to tissue homeostasis and regeneration.

EMBO Rep 2018 01 19;19(1):18-28. Epub 2017 Dec 19.

Hubrecht Institute-KNAW and University Medical Center, Utrecht, The Netherlands.

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http://dx.doi.org/10.15252/embr.201745130DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5757216PMC
January 2018

Neonatal rat cardiomyocytes as an in vitro model for circadian rhythms in the heart.

J Mol Cell Cardiol 2017 11 18;112:58-63. Epub 2017 Aug 18.

Department of Cardiology, University Medical Center Utrecht, The Netherlands; UMC Utrecht Regenerative Medicine Center, University Medical Center Utrecht, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.yjmcc.2017.08.009DOI Listing
November 2017

SCA1 Cells from the Heart Possess a Molecular Circadian Clock and Display Circadian Oscillations in Cellular Functions.

Stem Cell Reports 2017 09 10;9(3):762-769. Epub 2017 Aug 10.

Department of Cardiology, Division of Heart and Lungs, and Regenerative Medicine Center, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2017.07.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599230PMC
September 2017

Melatonin as a cardioprotective therapy following ST-segment elevation myocardial infarction: is it really promising? Reply.

Cardiovasc Res 2017 09;113(11):1418-1419

The Hatter Cardiovascular Institute, University College London, London, UK; The National Institute of Health Research University College London Hospitals Biomedical Research Centre, London, UK; Cardiovascular and Metabolic Disorders Program, Duke-National University of Singapore, Singapore; and National Heart Research Institute Singapore, National Heart Centre Singapore, Singapore; Department of Cardiology, Vall d'Hebron University Hospital and Research Institute. Universitat Autònoma, Barcelona, Spain; Department of Cardiology, Aarhus University Hospital Skejby, DK-8200, Aarhus N, Denmark; The Hatter Cardiovascular Institute, University College London, London, UK; Department of Physiology and Cell Biology, College of Medicine, University of South Alabama, Mobile, AL, USA; Experimental Renal and Cardiovascular Research, Department of Nephropathology, Institute of Pathology, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany; Duke University, Durham, NC, USA; Department of Medicine, Hatter Institute for Cardiovascular Research in Africa and South African Medical Research Council Inter-University Cape Heart Group, Faculty of Health Sciences, University of Cape Town, Chris Barnard Building, Anzio Road, Observatory, 7925, Cape Town, Western Cape, South Africa; Tamman Cardiovascular Research Institute, Sheba Medical Center, Tel Hashomer, Israel; Neufeld Cardiac Research Institute, Tel-Aviv University, Sheba Medical Center, Tel Hashomer, Israel; Sheba Center for Regenerative Medicine, Stem Cell, and Tissue Engineering, Tel Hashomer, Israel; Institute of Cardiology and Center of Excellence on Aging, 'G. d'Annunzio' University - Chieti, Italy; Texas Heart Institute and University of Texas Medical School in Houston, Department of Internal Medicine, Houston, TX, USA; Explorations Fonctionnelles Cardiovasculaires, Hôpital Louis Pradel, Lyon, France UMR 1060 (CarMeN), Université Claude Bernard, Lyon, France; Division of Cardiology, Department of Advanced Biomedical Sciences, Federico II University, Naples, Italy; University of Angers, University Hospital of Angers, Department of Cardiology, Angers, France; Institute of Physiology, Justus-Liebig University of Giessen, Giessen, Germany; Cardiology and UMC Utrecht Regenerative Medicine Center, University Medical Center Utrecht, the Netherlands; University Medical Center Utrecht, Division Heart and Lungs, and Hubrecht Institute, Utrecht, the Netherlands; Division of Cardiothoracic Surgery, Department of Surgery, Emory University, Atlanta, GA, USA; The Hatter Cardiovascular Institute, University College London, London, UK; and The National Institute of Health Research University College London Hospitals Biomedical Research Centre, London, UK; Cardiovascular Research Group, Department of Medical Biology, UiT, The Arctic University of Norway, Tromsø, Norway; Institute for Pathophysiology, West-German Heart and Vascular Center, University Hospital Essen, Essen, Germany; Department of Pharmacology and Pharmacotherapy, Semmelweis University, Budapest, Hungary; and Pharmahungary Group, Szeged, Hungary.

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http://dx.doi.org/10.1093/cvr/cvx137DOI Listing
September 2017

Circadian networks in human embryonic stem cell-derived cardiomyocytes.

EMBO Rep 2017 07 23;18(7):1199-1212. Epub 2017 May 23.

Division of Heart and Lungs, Department of Cardiology, University Medical Center Utrecht, Utrecht, The Netherlands

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http://dx.doi.org/10.15252/embr.201743897DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5494509PMC
July 2017

Defined Engineered Human Myocardium With Advanced Maturation for Applications in Heart Failure Modeling and Repair.

Circulation 2017 May 6;135(19):1832-1847. Epub 2017 Feb 6.

From Institute of Pharmacology and Toxicology, University Medical Center Göttingen, Germany (M.T., J.E.H., P.B., S.S., T.M., M.-L.C.L., E.L., F.R., S.Z., E. Wettwer, W.-H.Z.); German Center for Cardiovascular Research (DZHK), partner site Göttingen, Germany (M.T., J.E.H., P.B., S.S., T.M., M.-L.C.L., E.L., F.R., S.Z., E. Wingender, W.A.L., W.-H.Z.); Institute of Bioinformatics, University Medical Center Göttingen, Germany (S.Z., E. Wingender); Stanford Cardiovascular Institute (J.R., M.W., J.D.G., J.C.W.) and Department of Radiology (J.D.G., J.C.W.), Molecular Imaging Program, Stanford University School of Medicine, CA; The Sohnis Laboratory for Cardiac Electrophysiology and Regenerative Medicine, Technion-Israel Institute of Technology, Haifa (I.K., L.G.); Institute of Pharmacology and Toxicology, Technical University Dresden, Germany (E. Wettwer, U.R.); University Medical Center Utrecht and Hubrecht Institute, The Netherlands (P.D., L.W.v.L.); Leiden University Medical Center, The Netherlands (M.J.G.); Clinic for Cardiology and Pneumology, University Medical Center Göttingen, Germany (S.K., K.T., G.H., W.A.L.); Center for Applied Technology, Beckman Research Institute, City of Hope, Duarte, CA (L.A.C.); Department of Cardiovascular Physiology, Institute of Physiology, Ruhr University Bochum, Bochum, Germany (A.U., W.A.L.); New Laura and Isaac Perlmutter Cancer Center at New York University Langone (T.A., B.N.); and McEwen Centre for Regenerative Medicine, Toronto, Canada (G.K.). The current address for Dr Hudson is Laboratory for Cardiac Regeneration, School of Biomedical Sciences, The University of Queensland, Australia.

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https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.116.0
Publisher Site
http://dx.doi.org/10.1161/CIRCULATIONAHA.116.024145DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501412PMC
May 2017

Modeling the Human Scarred Heart In Vitro: Toward New Tissue Engineered Models.

Adv Healthc Mater 2017 Feb 1;6(3). Epub 2016 Dec 1.

Department of Cardiology, University Medical Center Utrecht, 3584CX, Utrecht, The Netherlands.

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http://dx.doi.org/10.1002/adhm.201600571DOI Listing
February 2017

Stem Cell Aging and Age-Related Cardiovascular Disease: Perspectives of Treatment by Ex-vivo Stem Cell Rejuvenation.

Curr Drug Targets 2015 ;16(8):780-5

Center of Excellence on Aging, "G. d'Annunzio" University, Via Paolicchi, 66100 Chieti, Italy.

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May 2016

Gelatin Microspheres as Vehicle for Cardiac Progenitor Cells Delivery to the Myocardium.

Adv Healthc Mater 2016 05 23;5(9):1071-9. Epub 2016 Feb 23.

Department of Cardiology, DH&L, University Medical Center Utrecht, Utrecht 3584, CX, The Netherlands.

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http://dx.doi.org/10.1002/adhm.201500861DOI Listing
May 2016

Heart failure specialization in Europe.

Eur J Heart Fail 2016 04 12;18(4):347-9. Epub 2016 Apr 12.

Department of Cardiology, University Medical Center Utrecht, University of Utrecht, Utrecht, the Netherlands.

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http://dx.doi.org/10.1002/ejhf.506DOI Listing
April 2016

Muscle-on-chip: An in vitro model for donor-host cardiomyocyte coupling.

J Cell Biol 2016 Feb 8;212(4):371-3. Epub 2016 Feb 8.

Division of Heart and Lungs, Department of Cardiology, University Medical Center Utrecht and Hubrecht Institute, 3584 CX Utrecht, Netherlands

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http://dx.doi.org/10.1083/jcb.201601074DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754721PMC
February 2016

Novel therapeutic strategies for cardioprotection.

Pharmacol Ther 2014 Oct 13;144(1):60-70. Epub 2014 May 13.

Department of Cardiology, University Medical Center Utrecht, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.pharmthera.2014.05.005DOI Listing
October 2014

Circadian rhythms in cell maturation.

Physiology (Bethesda) 2014 Jan;29(1):72-83

Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, The Netherlands;

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http://www.physiology.org/doi/10.1152/physiol.00036.2013
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http://dx.doi.org/10.1152/physiol.00036.2013DOI Listing
January 2014

Stem cells for cardiac repair: an introduction.

J Geriatr Cardiol 2013 Jun;10(2):186-97

Departments of Cardiology and Medical Physiology, Division of Heart and Lungs, University Medical Center Utrecht, P.O. box 85500, 3508 GA Utrecht, the Netherlands.

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http://dx.doi.org/10.3969/j.issn.1671-5411.2013.02.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708059PMC
June 2013

Embryonic template-based generation and purification of pluripotent stem cell-derived cardiomyocytes for heart repair.

J Cardiovasc Transl Res 2012 Oct 18;5(5):566-80. Epub 2012 Jul 18.

Division Heart and Lungs, University Medical Center Utrecht, Utrecht, The Netherlands.

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http://dx.doi.org/10.1007/s12265-012-9391-6DOI Listing
October 2012

miR-24 inhibits apoptosis and represses Bim in mouse cardiomyocytes.

J Exp Med 2011 Mar 7;208(3):549-60. Epub 2011 Mar 7.

Gladstone Institute of Cardiovascular Disease, University of California, San Francisco, San Francisco, CA 94143, USA.

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http://dx.doi.org/10.1084/jem.20101547DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3058576PMC
March 2011

Human embryonic stem cell-derived cardiomyocytes and cardiac repair in rodents.

Circ Res 2008 May 24;102(9):1008-10. Epub 2008 Apr 24.

Hubrecht Institute, Uppsalalaan 8, 3584 CT Utrecht, The Netherlands.

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http://dx.doi.org/10.1161/CIRCRESAHA.108.175505DOI Listing
May 2008

Stem-cell-based therapy and lessons from the heart.

Nature 2008 May;453(7193):322-9

Hubrecht Institute, Developmental Biology and Stem Cell Research, Uppsalalaan 8, 3584 CT Utrecht, The Netherlands.

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http://dx.doi.org/10.1038/nature07040DOI Listing
May 2008

MicroRNAs in the human heart: a clue to fetal gene reprogramming in heart failure.

Circulation 2007 Jul 2;116(3):258-67. Epub 2007 Jul 2.

University of Würzburg, University Hospital, Department of Internal Medicine I, Cardiology, Würzburg, Germany.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.107.687947DOI Listing
July 2007

Heart repair and stem cells.

J Physiol 2006 Dec 28;577(Pt 2):467-78. Epub 2006 Sep 28.

Hubrecht Laboratory, Interuniversity Cardiology Institute of the Netherlands, Utrecht, the Netherlands.

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http://dx.doi.org/10.1113/jphysiol.2006.115816DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1890431PMC
December 2006

Diversity of microRNAs in human and chimpanzee brain.

Nat Genet 2006 Dec 29;38(12):1375-7. Epub 2006 Oct 29.

Hubrecht Laboratory-KNAW, Uppsalalaan 8, 3584 CT Utrecht, The Netherlands.

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https://www.umcg.nl/EN/Research/ERIBA/Documents/Publications
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http://www.nature.com/doifinder/10.1038/ng1914
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http://dx.doi.org/10.1038/ng1914DOI Listing
December 2006

Cardiomyocytes derived from stem cells.

Ann Med 2005 ;37(7):499-512

Hubrecht Laboratory (Netherlands Institute for Developmental Biology), Utrecht, Netherlands.

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http://dx.doi.org/10.1080/07853890500327843DOI Listing
February 2006