Linda P Yu

Linda P C Yu

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Linda P Yu

Linda P C Yu

Publications by authors named "Linda P C Yu"

7Publications

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1PubMed Central Citations

Quantifying prion disease penetrance using large population control cohorts.

Sci Transl Med 2016 Jan;8(322):322ra9

Program in Medical and Population Genetics, Broad Institute of Massachusetts Institute of Technology (MIT) and Harvard, Cambridge, MA 02142, USA. Analytical and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA 02114, USA.

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http://dx.doi.org/10.1126/scitranslmed.aad5169DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4774245PMC
January 2016

Functional conformations for pyruvate carboxylase during catalysis explored by cryoelectron microscopy.

Structure 2014 Jun 29;22(6):911-22. Epub 2014 May 29.

Structural Biology Unit, Center for Cooperative Research in Biosciences, CIC bioGUNE, 48160 Derio, Spain; Department of Biochemistry and Molecular Biology, University of the Basque Country, P.O. Box 644, 48080 Bilbao, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.str.2014.04.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4090597PMC
June 2014

Characterizing the importance of the biotin carboxylase domain dimer for Staphylococcus aureus pyruvate carboxylase catalysis.

Biochemistry 2013 Jan 9;52(3):488-96. Epub 2013 Jan 9.

Department of Biological Sciences, Columbia University, New York, NY 10027, USA.

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http://dx.doi.org/10.1021/bi301294dDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3553216PMC
January 2013

Mechanism for the inhibition of the carboxyltransferase domain of acetyl-coenzyme A carboxylase by pinoxaden.

Proc Natl Acad Sci U S A 2010 Dec 6;107(51):22072-7. Epub 2010 Dec 6.

Department of Biological Sciences, Columbia University, New York, NY 10027, USA.

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http://dx.doi.org/10.1073/pnas.1012039107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3009786PMC
December 2010

Crystal structure of biotin carboxylase in complex with substrates and implications for its catalytic mechanism.

J Biol Chem 2009 Apr 12;284(17):11690-7. Epub 2009 Feb 12.

Department of Biological Sciences, Columbia University, New York, New York 10027, USA.

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http://dx.doi.org/10.1074/jbc.M805783200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2670172PMC
April 2009