Publications by authors named "Linda M Liau"

100Publications

Relative oxygen extraction fraction (rOEF) MR imaging reveals higher hypoxia in human epidermal growth factor receptor (EGFR) amplified compared with non-amplified gliomas.

Neuroradiology 2020 Oct 26. Epub 2020 Oct 26.

UCLA Brain Tumor Imaging Laboratory (BTIL), Center for Computer Vision and Imaging Biomarkers, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.

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http://dx.doi.org/10.1007/s00234-020-02585-8DOI Listing
October 2020

Multiparametric MR-PET measurements in hypermetabolic regions reflect differences in molecular status and tumor grade in treatment-naïve diffuse gliomas.

J Neurooncol 2020 Sep 14;149(2):337-346. Epub 2020 Sep 14.

UCLA Brain Tumor Imaging Laboratory (BTIL), Center for Computer Vision and Imaging Biomarkers, David Geffen School of Medicine, University of California Los Angeles, 924 Westwood Blvd, Suite 615, Los Angeles, CA, 90024, USA.

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http://dx.doi.org/10.1007/s11060-020-03613-6DOI Listing
September 2020

Decorin expression is associated with predictive diffusion MR phenotypes of anti-VEGF efficacy in glioblastoma.

Sci Rep 2020 Sep 9;10(1):14819. Epub 2020 Sep 9.

UCLA Brain Tumor Imaging Laboratory (BTIL), Center for Computer Vision and Imaging Biomarkers (CVIB), Dept. of Radiological Sciences, David Geffen School of Medicine, University of California Los Angeles, 924 Westwood Blvd, Suite 615, Los Angeles, CA, 90024, USA.

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http://dx.doi.org/10.1038/s41598-020-71799-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7481206PMC
September 2020

Human IDH mutant 1p/19q co-deleted gliomas have low tumor acidity as evidenced by molecular MRI and PET: a retrospective study.

Sci Rep 2020 07 17;10(1):11922. Epub 2020 Jul 17.

UCLA Brain Tumor Imaging Laboratory (BTIL), Center for Computer Vision and Imaging Biomarkers, University of California, Los Angeles, 924 Westwood Blvd., Suite 615, Los Angeles, CA, 90024, USA.

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http://dx.doi.org/10.1038/s41598-020-68733-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7367867PMC
July 2020

Results From the CheckMate 143 Clinical Trial: Stalemate or New Game Strategy for Glioblastoma Immunotherapy?

JAMA Oncol 2020 Jul;6(7):987-989

Department of Neurosurgery, David Geffen School of Medicine, University of California, Los Angeles.

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http://dx.doi.org/10.1001/jamaoncol.2020.0857DOI Listing
July 2020

Management of low-grade glioma: a systematic review and meta-analysis.

Neurooncol Pract 2019 Jul 18;6(4):249-258. Epub 2018 Aug 18.

Department of Neurosurgery, Penn State Milton S. Hershey Medical Center, Hershey, Pennsylvania, USA.

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http://dx.doi.org/10.1093/nop/npy034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660818PMC
July 2019

Improving B Correction for pH-Weighted Amine Proton Chemical Exchange Saturation Transfer (CEST) Imaging by Use of k-Means Clustering and Lorentzian Estimation.

Tomography 2018 Sep;4(3):123-137

UCLA Brain Tumor Imaging Laboratory (BTIL), Center for Computer Vision and Imaging Biomarkers, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA.

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http://dx.doi.org/10.18383/j.tom.2018.00017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173788PMC
September 2018

Cell-Based Immunotherapy of Gliomas.

Prog Neurol Surg 2018 10;32:90-100. Epub 2018 Jul 10.

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https://www.karger.com/Article/FullText/469683
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http://dx.doi.org/10.1159/000469683DOI Listing
October 2018

Correction to: First results on survival from a large Phase 3 clinical trial of an autologous dendritic cell vaccine in newly diagnosed glioblastoma.

J Transl Med 2018 06 29;16(1):179. Epub 2018 Jun 29.

Northwest Biotherapeutics Inc., Bethesda, MD, USA.

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https://translational-medicine.biomedcentral.com/articles/10
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http://dx.doi.org/10.1186/s12967-018-1552-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6026340PMC
June 2018

Mono-exponential, diffusion kurtosis and stretched exponential diffusion MR imaging response to chemoradiation in newly diagnosed glioblastoma.

J Neurooncol 2018 Sep 31;139(3):651-659. Epub 2018 May 31.

UCLA Brain Tumor Imaging Laboratory (BTIL), Center for Computer Vision and Imaging Biomarkers, University of California, Los Angeles, Los Angeles, CA, USA.

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http://dx.doi.org/10.1007/s11060-018-2910-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6126989PMC
September 2018

D-2-Hydroxyglutarate Is Necessary and Sufficient for Isocitrate Dehydrogenase 1 Mutant-Induced Promoter Methylation.

Mol Cancer Res 2018 06 15;16(6):947-960. Epub 2018 Mar 15.

Neuro-Oncology Program, Department of Neurology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California.

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http://dx.doi.org/10.1158/1541-7786.MCR-17-0367DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5984679PMC
June 2018

Risk factors for platelet transfusion in glioblastoma surgery.

J Clin Neurosci 2018 Apr 13;50:93-97. Epub 2018 Feb 13.

Department of Neurosurgery, Ronald Reagan UCLA Medical Center, United States; Department of Head and Neck Surgery, Ronald Reagan UCLA Medical Center, United States; Department of Radiation Oncology, Ronald Reagan UCLA Medical Center, United States; UCLA Jonsson Comprehensive Cancer Center, Ronald Reagan UCLA Medical Center, United States; Los Angeles Biomedical Research Institute (LA BioMed) at Harbor-UCLA Medical Center, Los Angeles, United States; David Geffen School of Medicine at the University of California, Los Angeles, United States. Electronic address:

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http://dx.doi.org/10.1016/j.jocn.2018.01.072DOI Listing
April 2018

Maintenance of Certification: Perceptions and Attitudes of Neurosurgeons.

Neurosurgery 2018 10;83(4):835-842

Department of Neurological Surgery, Mayo Clinic, Rochester, Minnesota.

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http://dx.doi.org/10.1093/neuros/nyx498DOI Listing
October 2018

Recognized focused practice: Does sub-specialty designation offer value to the neurosurgeon?

PLoS One 2017 14;12(12):e0189105. Epub 2017 Dec 14.

Department of Neurological Surgery, Mayo Clinic, Rochester, Minnesota, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0189105PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5730170PMC
January 2018

The Aging Neurosurgeon: When Is Enough, Enough? Attitudes Toward Ceasing Practice and Testing in Late Career.

Mayo Clin Proc 2017 Dec 15;92(12):1746-1752. Epub 2017 Nov 15.

Department of Neurological Surgery, Mayo Clinic, Rochester, MN.

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http://dx.doi.org/10.1016/j.mayocp.2017.09.004DOI Listing
December 2017

Detection of immune responses after immunotherapy in glioblastoma using PET and MRI.

Proc Natl Acad Sci U S A 2017 09 5;114(38):10220-10225. Epub 2017 Sep 5.

Department of Neurosurgery, David Geffen School of Medicine at UCLA, University of California, Los Angeles, CA 90095;

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http://dx.doi.org/10.1073/pnas.1706689114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617282PMC
September 2017

The whole-genome landscape of medulloblastoma subtypes.

Nature 2017 07;547(7663):311-317

Division of Molecular Genetics, German Cancer Research Center (DKFZ), Heidelberg, Germany.

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http://dx.doi.org/10.1038/nature22973DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5905700PMC
July 2017

Early experience with formalin-fixed paraffin-embedded (FFPE) based commercial clinical genomic profiling of gliomas-robust and informative with caveats.

Exp Mol Pathol 2017 08 27;103(1):87-93. Epub 2017 Jun 27.

Divison of Neuropathology, Department of Pathology and Laboratory Medicine, David Geffen School of Medicine, University of California-Los Angeles, Los Angeles, CA, United States; Brain Research Institute, University of California-Los Angeles, Los Angeles, CA, United States; Jonsson Comprehensive Cancer Center, University of California-Los Angeles, Los Angeles, CA, United States. Electronic address:

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http://dx.doi.org/10.1016/j.yexmp.2017.06.006DOI Listing
August 2017

Intertumoral Heterogeneity within Medulloblastoma Subgroups.

Authors:
Florence M G Cavalli Marc Remke Ladislav Rampasek John Peacock David J H Shih Betty Luu Livia Garzia Jonathon Torchia Carolina Nor A Sorana Morrissy Sameer Agnihotri Yuan Yao Thompson Claudia M Kuzan-Fischer Hamza Farooq Keren Isaev Craig Daniels Byung-Kyu Cho Seung-Ki Kim Kyu-Chang Wang Ji Yeoun Lee Wieslawa A Grajkowska Marta Perek-Polnik Alexandre Vasiljevic Cecile Faure-Conter Anne Jouvet Caterina Giannini Amulya A Nageswara Rao Kay Ka Wai Li Ho-Keung Ng Charles G Eberhart Ian F Pollack Ronald L Hamilton G Yancey Gillespie James M Olson Sarah Leary William A Weiss Boleslaw Lach Lola B Chambless Reid C Thompson Michael K Cooper Rajeev Vibhakar Peter Hauser Marie-Lise C van Veelen Johan M Kros Pim J French Young Shin Ra Toshihiro Kumabe Enrique López-Aguilar Karel Zitterbart Jaroslav Sterba Gaetano Finocchiaro Maura Massimino Erwin G Van Meir Satoru Osuka Tomoko Shofuda Almos Klekner Massimo Zollo Jeffrey R Leonard Joshua B Rubin Nada Jabado Steffen Albrecht Jaume Mora Timothy E Van Meter Shin Jung Andrew S Moore Andrew R Hallahan Jennifer A Chan Daniela P C Tirapelli Carlos G Carlotti Maryam Fouladi José Pimentel Claudia C Faria Ali G Saad Luca Massimi Linda M Liau Helen Wheeler Hideo Nakamura Samer K Elbabaa Mario Perezpeña-Diazconti Fernando Chico Ponce de León Shenandoah Robinson Michal Zapotocky Alvaro Lassaletta Annie Huang Cynthia E Hawkins Uri Tabori Eric Bouffet Ute Bartels Peter B Dirks James T Rutka Gary D Bader Jüri Reimand Anna Goldenberg Vijay Ramaswamy Michael D Taylor

Cancer Cell 2017 06;31(6):737-754.e6

The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, ON M5G 1X8, Canada; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, ON M5G 1X8, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON M5S 1A1, Canada; Division of Neurosurgery, The Hospital for Sick Children, Toronto, ON M5G 1X8, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2017.05.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6163053PMC
June 2017

Perfusion and diffusion MRI signatures in histologic and genetic subtypes of WHO grade II-III diffuse gliomas.

J Neurooncol 2017 Aug 25;134(1):177-188. Epub 2017 May 25.

UCLA Brain Tumor Imaging Laboratory (BTIL), Center for Computer Vision and Imaging Biomarkers, University of California, Los Angeles, Los Angeles, CA, USA.

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http://dx.doi.org/10.1007/s11060-017-2506-9DOI Listing
August 2017

Incidence, survival, pathology, and genetics of adult Latino Americans with glioblastoma.

J Neurooncol 2017 04 4;132(2):351-358. Epub 2017 Feb 4.

Divison of Neuropathology, Department of Pathology and Laboratory Medicine, David Geffen School of Medicine at UCLA, University of California-Los Angeles, 10833 LeConte Avenue, CHS13-145B, 90095, Los Angeles, CA, USA.

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http://link.springer.com/10.1007/s11060-017-2377-0
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http://dx.doi.org/10.1007/s11060-017-2377-0DOI Listing
April 2017

Multiple calcifying pseudoneoplasms of the neuraxis (MCAPNON): Distinct entity, CAPNON variant, or old neurocysticercosis?

Neuropathology 2017 Jun 10;37(3):233-240. Epub 2016 Nov 10.

Department of Pathology and Laboratory Medicine (Neuropathology), University of California at Los Angeles, Los Angeles, CA, USA.

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http://dx.doi.org/10.1111/neup.12349DOI Listing
June 2017

Simulation, phantom validation, and clinical evaluation of fast pH-weighted molecular imaging using amine chemical exchange saturation transfer echo planar imaging (CEST-EPI) in glioma at 3 T.

NMR Biomed 2016 11 15;29(11):1563-1576. Epub 2016 Sep 15.

UCLA Brain Tumor Imaging Laboratory (BTIL), Center for Computer Vision and Imaging Biomarkers, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, USA.

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http://doi.wiley.com/10.1002/nbm.3611
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http://dx.doi.org/10.1002/nbm.3611DOI Listing
November 2016

PD-1 blockade enhances the vaccination-induced immune response in glioma.

JCI Insight 2016 Jul;1(10)

Department of Neurosurgery, David Geffen School of Medicine at UCLA, UCLA, Los Angeles, California, USA; Brain Research Institute, David Geffen School of Medicine at UCLA, UCLA, Los Angeles, California, USA; Jonsson Comprehensive Cancer Center (JCCC), David Geffen School of Medicine at UCLA, UCLA, Los Angeles, California, USA; Department of Molecular and Medical Pharmacology, David Geffen School of Medicine at UCLA, UCLA, Los Angeles, California, USA.

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http://dx.doi.org/10.1172/jci.insight.87059DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951098PMC
July 2016

Therapeutic Impact of Cytoreductive Surgery and Irradiation of Posterior Fossa Ependymoma in the Molecular Era: A Retrospective Multicohort Analysis.

Authors:
Vijay Ramaswamy Thomas Hielscher Stephen C Mack Alvaro Lassaletta Tong Lin Kristian W Pajtler David T W Jones Betty Luu Florence M G Cavalli Kenneth Aldape Marc Remke Martin Mynarek Stefan Rutkowski Sridharan Gururangan Roger E McLendon Eric S Lipp Christopher Dunham Juliette Hukin David D Eisenstat Dorcas Fulton Frank K H van Landeghem Mariarita Santi Marie-Lise C van Veelen Erwin G Van Meir Satoru Osuka Xing Fan Karin M Muraszko Daniela P C Tirapelli Sueli M Oba-Shinjo Suely K N Marie Carlos G Carlotti Ji Yeoun Lee Amulya A Nageswara Rao Caterina Giannini Claudia C Faria Sofia Nunes Jaume Mora Ronald L Hamilton Peter Hauser Nada Jabado Kevin Petrecca Shin Jung Luca Massimi Massimo Zollo Giuseppe Cinalli László Bognár Almos Klekner Tibor Hortobágyi Sarah Leary Ralph P Ermoian James M Olson Jeffrey R Leonard Corrine Gardner Wieslawa A Grajkowska Lola B Chambless Jason Cain Charles G Eberhart Sama Ahsan Maura Massimino Felice Giangaspero Francesca R Buttarelli Roger J Packer Lyndsey Emery William H Yong Horacio Soto Linda M Liau Richard Everson Andrew Grossbach Tarek Shalaby Michael Grotzer Matthias A Karajannis David Zagzag Helen Wheeler Katja von Hoff Marta M Alonso Teresa Tuñon Ulrich Schüller Karel Zitterbart Jaroslav Sterba Jennifer A Chan Miguel Guzman Samer K Elbabaa Howard Colman Girish Dhall Paul G Fisher Maryam Fouladi Amar Gajjar Stewart Goldman Eugene Hwang Marcel Kool Harshad Ladha Elizabeth Vera-Bolanos Khalida Wani Frank Lieberman Tom Mikkelsen Antonio M Omuro Ian F Pollack Michael Prados H Ian Robins Riccardo Soffietti Jing Wu Phillipe Metellus Uri Tabori Ute Bartels Eric Bouffet Cynthia E Hawkins James T Rutka Peter Dirks Stefan M Pfister Thomas E Merchant Mark R Gilbert Terri S Armstrong Andrey Korshunov David W Ellison Michael D Taylor

J Clin Oncol 2016 07 6;34(21):2468-77. Epub 2016 Jun 6.

Vijay Ramaswamy, Stephen C. Mack, Alvaro Lassaletta, Betty Luu, Florence M.G. Cavalli, Uri Tabori, Ute Bartels, Eric Bouffet, Cynthia E. Hawkins, James T. Rutka, Peter Dirks, and Michael D. Taylor, The Hospital for Sick Children; Vijay Ramaswamy, Kenneth Aldape, James T. Rutka, and Michael D. Taylor, University of Toronto; Kenneth Aldape, Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario; Christopher Dunham and Juliette Hukin, British Columbia Children's Hospital; Juliette Hukin, University of British Columbia, Vancouver, British Columbia; David D. Eisenstat, Dorcas Fulton, and Frank K.H. van Landeghem, University of Alberta, Edmonton; Jennifer A. Chan, University of Calgary, Calgary, Alberta; Nada Jabado and Kevin Petrecca, McGill University, Montreal, Quebec, Canada; Thomas Hielscher, Kristian W. Pajtler, David T.W. Jones, Marcel Kool, Stefan M. Pfister, and Andrey Korshunov, German Cancer Research Center; Stefan M. Pfister, University Hospital Heidelberg, Heidelberg; Marc Remke, University Hospital Düsseldorf, Düsseldorf; Martin Mynarek, Stefan Rutkowski, and Katja von Hoff, University Medical Center Hamburg-Eppendorf, Hamburg; Ulrich Schüller, Ludwig-Maximilians-Universität, Munich, Germany; Stephen C. Mack, Cleveland Clinic Foundation, Cleveland; Maryam Fouladi, University of Cincinnati, Cincinnati Children's Hospital Medical Center, Cincinnati, OH; Tong Lin, Amar Gajjar, Thomas E. Merchant, and David W. Ellison, St Jude Children's Research Hospital, Memphis; Lola B. Chambless, Vanderbilt Medical Center, Nashville, TN; Sridharan Gururangan, Roger E. McLendon, and Eric S. Lipp, Duke University, Durham; Jing Wu, University of North Carolina at Chapel Hill, Chapel Hill, NC; Mariarita Santi, Children's Hospital of Philadelphia; Lyndsey Emery, Hospital of the University of Pennsylvania, Philadelphia; Ronald L. Hamilton and Ian F. Pollack, University of Pittsburgh School of Medicine; Frank Lieberman, University of Pittsburgh Medical Cen

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http://dx.doi.org/10.1200/JCO.2015.65.7825DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4962737PMC
July 2016

Large-scale assessment of the gliomasphere model system.

Neuro Oncol 2016 10 25;18(10):1367-78. Epub 2016 Apr 25.

Department of Biological Chemistry, University of California, Los Angeles, California (D.R.L.); Department of Psychiatry and Biobehavioral Sciences and Semel Institute for Neuroscience & Human Behavior, University of California, Los Angeles, California (T.J.C., M.Y.S.S., J.M., F.G., M.C.G., G.C., H.I.K.); Department of Pharmacology, University of California, Los Angeles, California (J.S.); Department of Pathology, University of California, Los Angeles, California (W.H.Y.); Department of Neurology, University of California, Los Angeles, California (T.F.C., A.L., G.C.); Department of Neurosurgery, University of California, Los Angeles, California (L.M.L.); Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, University of California, Los Angeles, California (H.I.K.); The Jonsson Comprehensive Cancer Center, University of California, Los Angeles, California (W.H.Y., T.F.C., L.M.L., A.L., H.I.K.)

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http://dx.doi.org/10.1093/neuonc/now045DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5035518PMC
October 2016

Contrast-enhancing tumor growth dynamics of preoperative, treatment-naive human glioblastoma.

Cancer 2016 06 21;122(11):1718-27. Epub 2016 Mar 21.

UCLA Neuro-Oncology Program, David Geffen School of Medicine, University of California-Los Angeles, Los Angeles, California.

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http://dx.doi.org/10.1002/cncr.29957DOI Listing
June 2016

Ribosomal Proteins RPS11 and RPS20, Two Stress-Response Markers of Glioblastoma Stem Cells, Are Novel Predictors of Poor Prognosis in Glioblastoma Patients.

PLoS One 2015 27;10(10):e0141334. Epub 2015 Oct 27.

Department of Surgery/Surgical-Oncology, University of California Los Angeles, Los Angeles, California, United States of America; Jonsson Comprehensive Cancer Center, David Geffen School of Medicine at University of California Los Angeles, Los Angeles, California, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0141334PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4624638PMC
June 2016

Efficacy of systemic adoptive transfer immunotherapy targeting NY-ESO-1 for glioblastoma.

Neuro Oncol 2016 Mar 1;18(3):368-78. Epub 2015 Sep 1.

Department of Neurosurgery, University of California Los Angeles, Los Angeles, California (R.G.E., J.P.A., D.N.L., H.S., R.S., M.C.G., C.A.K., L.M.L., R.M.P.); Department of Molecular and Medical Pharmacology, University of California Los Angeles, Los Angeles, California (D.N.L., R.M.P.); Department of Pathology and Laboratory Medicine, University of California Los Angeles, Los Angeles, California (W.H.Y.); Department of Biostatistics, University of California Los Angeles, Los Angeles, California (N.L., G.L.); Brain Research Institute, University of California Los Angeles, Los Angeles, California (C.A.K., L.M.L., R.M.P.); Jonsson Comprehensive Cancer Center, David Geffen School of Medicine at UCLA, University of California Los Angeles, Los Angeles, California (C.A.K., L.M.L., R.M.P.).

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http://dx.doi.org/10.1093/neuonc/nov153DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4767237PMC
March 2016

HLA Markers DQ8 and DR53 Are Associated With Lymphocytic Hypophysitis and May Aid in Differential Diagnosis.

J Clin Endocrinol Metab 2015 Nov 28;100(11):4092-7. Epub 2015 Aug 28.

Departments of Medicine (A.P.H., B.S.), Neurosurgery (A.P.H., M.B., L.M.L.), and Pathology (W.H.Y.), UCLA-David Geffen School of Medicine, Los Angeles, California 90095; and Immunogenetics and Transplantation Laboratory (R.R.), Department of Surgery, University of California San Francisco, San Francisco, California 94143.

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http://dx.doi.org/10.1210/jc.2015-2702DOI Listing
November 2015

pH-weighted molecular imaging of gliomas using amine chemical exchange saturation transfer MRI.

Neuro Oncol 2015 Nov 24;17(11):1514-24. Epub 2015 Jun 24.

Department of Radiological Sciences (R.J.H., W.B.P., B.M.E.), Department of Biomedical Physics (R.J.H., B.M.E.), Department of Neurology (T.F.C., A.L., P.L.N.), Department of Neurosurgery, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California (L.M.L., R.M.P., J.P.A.); Department of Biomedical Sciences and Imaging, Cedars-Sinai Medical Center, Los Angeles, California (D.L.); Department of Bioengineering (D.L., B.M.E.), Department of Pathology and Laboratory Medicine, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California (W.H.Y.).

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http://dx.doi.org/10.1093/neuonc/nov106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4648305PMC
November 2015

Introduction: brain tumor immunotherapy.

J Neurooncol 2015 Jul;123(3):321-2

Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, MD, 21287, USA,

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http://dx.doi.org/10.1007/s11060-015-1848-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4515570PMC
July 2015

Dendritic cell immunotherapy for brain tumors.

J Neurooncol 2015 Jul 3;123(3):425-32. Epub 2015 Jun 3.

Department of Neurosurgery, David Geffen School of Medicine at UCLA, University of California Los Angeles, Los Angeles, CA, 90095, USA.

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http://dx.doi.org/10.1007/s11060-015-1830-1DOI Listing
July 2015

MRI perfusion measurements calculated using advanced deconvolution techniques predict survival in recurrent glioblastoma treated with bevacizumab.

J Neurooncol 2015 May 15;122(3):497-505. Epub 2015 Mar 15.

UCLA Brain Tumor Imaging Laboratory (BTIL), Department of Radiological Sciences, David Geffen School of Medicine, University of California Los Angeles, 924 Westwood Blvd., Suite 615, Los Angeles, CA, 90024, USA.

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http://dx.doi.org/10.1007/s11060-015-1755-8DOI Listing
May 2015

Radial mobility and cytotoxic function of retroviral replicating vector transduced, non-adherent alloresponsive T lymphocytes.

J Vis Exp 2015 Feb 11(96). Epub 2015 Feb 11.

Department of Neurosurgery, UCLA David Geffen School of Medicine; Brain Research Institute, UCLA David Geffen School of Medicine; Jonsson Comprehensive Cancer Center, UCLA David Geffen School of Medicine;

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http://dx.doi.org/10.3791/52416DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354631PMC
February 2015

Relationship Between [18F]FDOPA PET Uptake, Apparent Diffusion Coefficient (ADC), and Proliferation Rate in Recurrent Malignant Gliomas.

Mol Imaging Biol 2015 Jun;17(3):434-42

Department of Radiological Sciences, David Geffen School of Medicine, University of California Los Angeles, 924 Westwood Blvd, Suite 615, Los Angeles, CA, 90024, USA.

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http://dx.doi.org/10.1007/s11307-014-0807-3DOI Listing
June 2015

The histone deacetylase inhibitor, LBH589, promotes the systemic cytokine and effector responses of adoptively transferred CD8+ T cells.

J Immunother Cancer 2014 15;2. Epub 2014 Apr 15.

Department of Molecular and Medical Pharmacology, 650 Charles E. Young Drive South, 23-120 Center for Health Sciences, Los Angeles, CA 90095-1735, USA ; Department of Neurosurgery, University of California-Los Angeles School of Medicine, Center for Health Sciences, Room 74-145 CHS, 10833 Le Conte Avenue, Box 956901, Los Angeles, CA 90095-6901, USA ; Jonsson Comprehensive Cancer Center, University of California-Los Angeles School of Medicine, 8-684 Factor Building, Box 951781, Los Angeles, CA 90095-1781, USA ; Brain Research Institute, University of California-Los Angeles School of Medicine, 695 Charles E. Young Drive South, Los Angeles, CA 90095, USA.

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http://dx.doi.org/10.1186/2051-1426-2-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4105687PMC
July 2014

Deferred use of bevacizumab for recurrent glioblastoma is not associated with diminished efficacy.

Neuro Oncol 2014 Jun 13;16(6):815-22. Epub 2014 Mar 13.

Department of Neurosciences, University of California San Diego, San Diego, California (D.E.P.); Department of Neurology, David Geffen School of Medicine at University of California Los Angeles, Los Angeles, California (J.S., R.R.M., R.C., S.L., S.L., M.Z., P.L.N., T.F.C., A.L.); Department of Neurosurgery, David Geffen School of Medicine at University of California Los Angeles, Los Angeles, California (A.P.C., L.M.L.); Department of Pathology, David Geffen School of Medicine at University of California Los Angeles, Los Angeles, California (D.E.S., W.H.Y.); Peterhouse, University of Cambridge, Cambridge, UK (J.W.); Department of Radiological Sciences, David Geffen School of Medicine at University of California Los Angeles, Los Angeles, California (B.M.E., W.B.P.); Kaiser Permanente Southern California, Los Angeles, California (J.Q., R.M.G.); Department of Biomathematics, David Geffen School of Medicine at University of California Los Angeles, Los Angeles, California (H.W., R.E.).

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http://dx.doi.org/10.1093/neuonc/nou028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4022228PMC
June 2014

Cytogenetic prognostication within medulloblastoma subgroups.

J Clin Oncol 2014 Mar 3;32(9):886-96. Epub 2014 Feb 3.

David J.H. Shih, Marc Remke, Vijay Ramaswamy, Betty Luu, Yuan Yao, Xin Wang, Adrian M. Dubuc, Livia Garzia, John Peacock, Stephen C. Mack, Xiaochong Wu, Adi Rolider, A. Sorana Morrissy, Florence M.G. Cavalli, Claudia C. Faria, Stephen W. Scherer, Uri Tabori, Cynthia E. Hawkins, David Malkin, Eric Bouffet, James T. Rutka, and Michael D. Taylor, Hospital for Sick Children; David J.H. Shih, Marc Remke, Vijay Ramaswamy, Yuan Yao, Xin Wang, Adrian M. Dubuc, John Peacock, Stephen C. Mack, and Michael D. Taylor, University of Toronto, Toronto; Boleslaw Lach, McMaster University, Hamilton, Ontario; Jennifer A. Chan, University of Calgary, Calgary, Alberta; Steffen Albrecht, Adam Fontebasso, and Nada Jabado, McGill University, Montreal, Quebec, Canada; Paul A. Northcott, Andrey Korshunov, Marcel Kool, David T.W. Jones, and Stefan M. Pfister, German Cancer Research Center; Stefan M. Pfister, University Hospital Heidelberg, Heidelberg; Ulrich Schüller, Ludwig-Maximilians-University, Munich; Stefan Rutkowski, University Medical Center Hamburg-Eppendorf, Hamburg, Germany; Karel Zitterbart, Masaryk University School of Medicine; Karel Zitterbart and Leos Kren, University Hospital Brno, Brno, Czech Republic; Toshihiro Kumabe and Teiji Tominaga, Tohoku University Graduate School of Medicine, Sendai, Japan; Young Shin Ra, University of Ulsan, Asan Medical Center; Ji-Yeoun Lee, Byung-Kyu Cho, Seung-Ki Kim, and Kyu-Chang Wang, Seoul National University Children's Hospital, Seoul; Shin Jung, Chonnam National University Research Institute of Medical Sciences, Chonnam National University Hwasun Hospital and Medical School, Chonnam, South Korea; Peter Hauser and Miklós Garami, Semmelweis University, Budapest; László Bognár and Almos Klekner, University of Debrecen, Medical and Health Science Centre, Debrecen, Hungary; Shenandoah Robinson, Boston Children's Hospital; Scott L. Pomeroy, Harvard Medical School, Boston, MA; Ali G. Saad, University of Arkansas for Medical Sciences, Little

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http://dx.doi.org/10.1200/JCO.2013.50.9539DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3948094PMC
March 2014

C-terminally truncated form of αB-crystallin is associated with IDH1 R132H mutation in anaplastic astrocytoma.

J Neurooncol 2014 Mar 29;117(1):53-65. Epub 2014 Jan 29.

Department of Biological Chemistry, David Geffen School of Medicine at UCLA, 615 Charles E. Young Dr. South, Los Angeles, CA, 90095, USA.

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March 2014

Nonlinear distortion correction of diffusion MR images improves quantitative DTI measurements in glioblastoma.

J Neurooncol 2014 Feb 7;116(3):551-8. Epub 2013 Dec 7.

Department of Radiological Sciences, David Geffen School of Medicine, University of California, Los Angeles, 924 Westwood Blvd, Suite 615, Los Angeles, CA, USA.

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http://dx.doi.org/10.1007/s11060-013-1320-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3918907PMC
February 2014

Protective properties of radio-chemoresistant glioblastoma stem cell clones are associated with metabolic adaptation to reduced glucose dependence.

PLoS One 2013 18;8(11):e80397. Epub 2013 Nov 18.

Department of Surgery/Surgical Oncology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, United States of America ; Department of Neurosurgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832364PMC
July 2014

TERT promoter mutations are highly recurrent in SHH subgroup medulloblastoma.

Acta Neuropathol 2013 Dec 31;126(6):917-29. Epub 2013 Oct 31.

The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, ON, Canada.

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http://dx.doi.org/10.1007/s00401-013-1198-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3830749PMC
December 2013

BEAMing and Droplet Digital PCR Analysis of Mutant IDH1 mRNA in Glioma Patient Serum and Cerebrospinal Fluid Extracellular Vesicles.

Mol Ther Nucleic Acids 2013 Jul 23;2:e109. Epub 2013 Jul 23.

1] Department of Neurology, Massachusetts General Hospital, and Neuroscience Program, Harvard Medical School, Boston, Massachusetts, USA [2] Department of Radiology, Massachusetts General Hospital, and Neuroscience Program, Harvard Medical School, Boston, Massachusetts, USA [3] Program, Harvard-MIT Division of Health, Science, and Technology, Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1038/mtna.2013.28DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3732870PMC
July 2013

Autologous tumor lysate-pulsed dendritic cell immunotherapy for pediatric patients with newly diagnosed or recurrent high-grade gliomas.

Anticancer Res 2013 May;33(5):2047-56

Department of Pediatrics, Division of Pediatric Hematology/ Oncology, Harbor-UCLA Medical Center/LA Biomed, David Geffen School of Medicine UCLA, Torrance, CA 90502, USA.

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May 2013

Quantitative probabilistic functional diffusion mapping in newly diagnosed glioblastoma treated with radiochemotherapy.

Neuro Oncol 2013 Mar 28;15(3):382-90. Epub 2012 Dec 28.

Department of Radiological Sciences, David Geffen School of Medicine, University of California Los Angeles, 924 Westwood Blvd., Ste. 615, Los Angeles, CA 90024, USA.

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http://dx.doi.org/10.1093/neuonc/nos314DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3578489PMC
March 2013

Overexpression of isocitrate dehydrogenase mutant proteins renders glioma cells more sensitive to radiation.

Neuro Oncol 2013 Jan 31;15(1):57-68. Epub 2012 Oct 31.

Department of Neurology, David Geffen School of Medicine at UCLA, University of California at Los Angeles, Los Angeles, California 90095, USA.

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http://dx.doi.org/10.1093/neuonc/nos261DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3534418PMC
January 2013

Subgroup-specific structural variation across 1,000 medulloblastoma genomes.

Authors:
Paul A Northcott David J H Shih John Peacock Livia Garzia A Sorana Morrissy Thomas Zichner Adrian M Stütz Andrey Korshunov Jüri Reimand Steven E Schumacher Rameen Beroukhim David W Ellison Christian R Marshall Anath C Lionel Stephen Mack Adrian Dubuc Yuan Yao Vijay Ramaswamy Betty Luu Adi Rolider Florence M G Cavalli Xin Wang Marc Remke Xiaochong Wu Readman Y B Chiu Andy Chu Eric Chuah Richard D Corbett Gemma R Hoad Shaun D Jackman Yisu Li Allan Lo Karen L Mungall Ka Ming Nip Jenny Q Qian Anthony G J Raymond Nina T Thiessen Richard J Varhol Inanc Birol Richard A Moore Andrew J Mungall Robert Holt Daisuke Kawauchi Martine F Roussel Marcel Kool David T W Jones Hendrick Witt Africa Fernandez-L Anna M Kenney Robert J Wechsler-Reya Peter Dirks Tzvi Aviv Wieslawa A Grajkowska Marta Perek-Polnik Christine C Haberler Olivier Delattre Stéphanie S Reynaud François F Doz Sarah S Pernet-Fattet Byung-Kyu Cho Seung-Ki Kim Kyu-Chang Wang Wolfram Scheurlen Charles G Eberhart Michelle Fèvre-Montange Anne Jouvet Ian F Pollack Xing Fan Karin M Muraszko G Yancey Gillespie Concezio Di Rocco Luca Massimi Erna M C Michiels Nanne K Kloosterhof Pim J French Johan M Kros James M Olson Richard G Ellenbogen Karel Zitterbart Leos Kren Reid C Thompson Michael K Cooper Boleslaw Lach Roger E McLendon Darell D Bigner Adam Fontebasso Steffen Albrecht Nada Jabado Janet C Lindsey Simon Bailey Nalin Gupta William A Weiss László Bognár Almos Klekner Timothy E Van Meter Toshihiro Kumabe Teiji Tominaga Samer K Elbabaa Jeffrey R Leonard Joshua B Rubin Linda M Liau Erwin G Van Meir Maryam Fouladi Hideo Nakamura Giuseppe Cinalli Miklós Garami Peter Hauser Ali G Saad Achille Iolascon Shin Jung Carlos G Carlotti Rajeev Vibhakar Young Shin Ra Shenandoah Robinson Massimo Zollo Claudia C Faria Jennifer A Chan Michael L Levy Poul H B Sorensen Matthew Meyerson Scott L Pomeroy Yoon-Jae Cho Gary D Bader Uri Tabori Cynthia E Hawkins Eric Bouffet Stephen W Scherer James T Rutka David Malkin Steven C Clifford Steven J M Jones Jan O Korbel Stefan M Pfister Marco A Marra Michael D Taylor

Nature 2012 Aug;488(7409):49-56

Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario M5G 1L7, Canada.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3683624PMC
August 2012

Use of language mapping to aid in resection of gliomas in eloquent brain regions.

Neurosurg Clin N Am 2012 Jul;23(3):497-506

UCLA Department of Neurosurgery, David Geffen School of Medicine at UCLA, Los Angeles, CA 90096-6901, USA.

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http://dx.doi.org/10.1016/j.nec.2012.05.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3618998PMC
July 2012

IDH mutations in human glioma.

Neurosurg Clin N Am 2012 Jul 31;23(3):471-80. Epub 2012 May 31.

Department of Neurosurgery, University of California Los Angeles, Los Angeles, CA 90095-6901, USA.

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http://dx.doi.org/10.1016/j.nec.2012.04.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3618997PMC
July 2012

Endogenous vaults and bioengineered vault nanoparticles for treatment of glioblastomas: implications for future targeted therapies.

Neurosurg Clin N Am 2012 Jul 31;23(3):451-8. Epub 2012 May 31.

Department of Biological Chemistry, David Geffen School of Medicine at University of California, Los Angeles, Los Angeles, CA 90095-1737, USA.

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http://dx.doi.org/10.1016/j.nec.2012.04.012DOI Listing
July 2012

Monitoring of regulatory T cell frequencies and expression of CTLA-4 on T cells, before and after DC vaccination, can predict survival in GBM patients.

PLoS One 2012 2;7(4):e32614. Epub 2012 Apr 2.

Department of Neurosurgery, David Geffen School of Medicine at UCLA, University of California Los Angeles, Los Angeles, California, United States of America.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3317661PMC
July 2012

Functional diffusion maps (fDMs) evaluated before and after radiochemotherapy predict progression-free and overall survival in newly diagnosed glioblastoma.

Neuro Oncol 2012 Mar 22;14(3):333-43. Epub 2012 Jan 22.

Department of Radiological Sciences, David Geffen School of Medicine, University of California Los Angeles, 924 Westwood Blvd, Suite 615, Los Angeles, CA 90024, USA.

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http://dx.doi.org/10.1093/neuonc/nor220DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3280805PMC
March 2012

Decitabine immunosensitizes human gliomas to NY-ESO-1 specific T lymphocyte targeting through the Fas/Fas ligand pathway.

J Transl Med 2011 Nov 7;9:192. Epub 2011 Nov 7.

Graduate Program in Physiological Sciences, David Geffen School of Medicine at UCLA, University of California Los Angeles, Los Angeles, California, 90095, USA.

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http://dx.doi.org/10.1186/1479-5876-9-192DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3229551PMC
November 2011