Linda Baughn

Linda Baughn

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Linda Baughn

Linda Baughn

Publications by authors named "Linda Baughn"

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A near-haploid clone harboring a BCR/ABL1 gene fusion in an adult patient with newly diagnosed B-lymphoblastic leukemia.

Genes Chromosomes Cancer 2019 09 18;58(9):665-668. Epub 2019 Mar 18.

Division of Laboratory Genetics and Genomics, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota.

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http://dx.doi.org/10.1002/gcc.22744DOI Listing
September 2019

Whole Genome Mate-pair Sequencing of Plasma Cell Neoplasm as a Novel Diagnostic Strategy: A Case of Unrecognized t(2;11) Structural Variation.

Clin Lymphoma Myeloma Leuk 2019 Sep 18;19(9):598-602. Epub 2019 Jun 18.

Division of Laboratory Genetics and Genomics, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN. Electronic address:

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http://dx.doi.org/10.1016/j.clml.2019.06.006DOI Listing
September 2019

Characterization of a rarely reported STAT5B/RARA gene fusion in a young adult with newly diagnosed acute promyelocytic leukemia with resistance to ATRA therapy.

Cancer Genet 2019 Sep 12;237:51-54. Epub 2019 Jun 12.

Division of Laboratory Medicine and Pathology, Department of Laboratory Medicine and Pathology, Mayo Clinic, 200 First Street SW, Rochester, MN, United States.

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http://dx.doi.org/10.1016/j.cancergen.2019.06.007DOI Listing
September 2019

Fluorescence In Situ Hybridization for TP63 Rearrangements in T-cell Lymphomas: Single Site Experience of 470 Patients and Implications for Clinical Testing.

Histopathology 2019 Sep 26. Epub 2019 Sep 26.

Department of Laboratory Medicine and Pathology, Division of Hematopathology, Mayo Clinic, Rochester, MN, USA.

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http://dx.doi.org/10.1111/his.14005DOI Listing
September 2019

Acute leukemias harboring KMT2A/MLLT10 fusion: a 10-year experience from a single genomics laboratory.

Genes Chromosomes Cancer 2019 08 19;58(8):567-577. Epub 2019 Mar 19.

Division of Laboratory Genetics and Genomics, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota.

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http://dx.doi.org/10.1002/gcc.22741DOI Listing
August 2019

Use of mate-pair sequencing to characterize a complex cryptic BCR/ABL1 rearrangement observed in a newly diagnosed case of chronic myeloid leukemia.

Hum Pathol 2019 Jul 26;89:109-114. Epub 2018 Sep 26.

Department of Laboratory Medicine and Pathology, Division of Laboratory Genetics and Genomics, Mayo Clinic, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1016/j.humpath.2018.09.010DOI Listing
July 2019

The future of myeloma precision medicine: integrating the compendium of known drug resistance mechanisms with emerging tumor profiling technologies.

Leukemia 2019 04 25;33(4):863-883. Epub 2019 Jan 25.

Department of Genetics, Cell Biology & Development, University of Minnesota, Minneapolis, MN, USA.

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http://dx.doi.org/10.1038/s41375-018-0362-zDOI Listing
April 2019

Molecular signatures of multiple myeloma progression through single cell RNA-Seq.

Blood Cancer J 2019 01 3;9(1). Epub 2019 Jan 3.

Genome Analysis Core, Medical Genome Facility, Center for Individualized Medicine, Mayo Clinic, Rochester, MN, USA.

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http://dx.doi.org/10.1038/s41408-018-0160-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6318319PMC
January 2019

KMT2A (MLL) rearrangements observed in pediatric/young adult T-lymphoblastic leukemia/lymphoma: A 10-year review from a single cytogenetic laboratory.

Genes Chromosomes Cancer 2018 11 10;57(11):541-546. Epub 2018 Sep 10.

Division of Laboratory Genetics and Genomics, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota.

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http://dx.doi.org/10.1002/gcc.22666DOI Listing
November 2018

The Utilization of Chromosomal Microarray Technologies for Hematologic Neoplasms: An ACLPS Critical Review.

Am J Clin Pathol 2018 Oct;150(5):375-384

Department of Laboratory Medicine and Pathology, Division of Laboratory Genetics and Genomics, Mayo Clinic, Rochester, MN.

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http://dx.doi.org/10.1093/ajcp/aqy076DOI Listing
October 2018

Phenotypic and functional characterization of a bortezomib-resistant multiple myeloma cell line by flow and mass cytometry.

Leuk Lymphoma 2017 08 16;58(8):1931-1940. Epub 2016 Dec 16.

d Division of Hematopathology, Department of Laboratory Medicine and Pathology , University of Minnesota , Minneapolis , MN , USA.

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http://dx.doi.org/10.1080/10428194.2016.1266621DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5504883PMC
August 2017

CNV-RF Is a Random Forest-Based Copy Number Variation Detection Method Using Next-Generation Sequencing.

J Mol Diagn 2016 11 3;18(6):872-881. Epub 2016 Sep 3.

Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, Minnesota. Electronic address:

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http://dx.doi.org/10.1016/j.jmoldx.2016.07.001DOI Listing
November 2016

Bosutinib, a Lyn/Btk inhibiting tyrosine kinase inhibitor, is ineffective in advanced systemic mastocytosis.

Am J Hematol 2015 Apr 2;90(4):E74. Epub 2015 Mar 2.

Division of HematologyôOncology and Transplantation, Department of Medicine, University of Minnesota, Minneapolis, Minnesota.

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http://dx.doi.org/10.1002/ajh.23942DOI Listing
April 2015

Utilization of translational bioinformatics to identify novel biomarkers of bortezomib resistance in multiple myeloma.

J Cancer 2014 21;5(9):720-7. Epub 2014 Sep 21.

6. Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN.

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http://dx.doi.org/10.7150/jca.9864DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4216795PMC
November 2014

Bortezomib resistance can be reversed by induced expression of plasma cell maturation markers in a mouse in vitro model of multiple myeloma.

PLoS One 2013 29;8(10):e77608. Epub 2013 Oct 29.

Department of Genetics, Cell Biology and Development, University of Minnesota, Minneapolis, Minnesota, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0077608PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3812176PMC
August 2014

Stabilization of activation induced cytidine deaminase by bortezomib does not confer increased drug target mutation frequency.

Leuk Lymphoma 2014 Jan 4;55(1):220-2. Epub 2013 Jun 4.

Department of Genetics, Cell Biology and Development.

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http://dx.doi.org/10.3109/10428194.2013.797575DOI Listing
January 2014

Recombinase-mediated cassette exchange as a novel method to study somatic hypermutation in Ramos cells.

MBio 2011 11;2(5). Epub 2011 Oct 11.

Departments of Cell Biology, Albert Einstein College of Medicine, Bronx, New York, USA.

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http://dx.doi.org/10.1128/mBio.00186-11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3190358PMC
January 2012

SH2-containing inositol 5'-phosphatase inhibits transformation of Abelson murine leukemia virus.

J Virol 2011 Sep 22;85(17):9239-42. Epub 2011 Jun 22.

Immunology Graduate Program, Sackler School of Graduate Biomedical Sciences, Tufts University School of Medicine, Boston, Massachusetts 02111, USA.

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http://dx.doi.org/10.1128/JVI.05115-11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3165847PMC
September 2011

CDK2 phosphorylation of Smad2 disrupts TGF-beta transcriptional regulation in resistant primary bone marrow myeloma cells.

J Immunol 2009 Feb;182(4):1810-7

Department of Pathology, Weill Medical College of Cornell University, New York, NY 10065, USA.

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http://dx.doi.org/10.4049/jimmunol.0713726DOI Listing
February 2009

Disruption of the Shc/Grb2 complex during abelson virus transformation affects proliferation, but not apoptosis.

J Virol 2005 Feb;79(4):2325-34

Immunology Graduate Program, Sacker School of Graduate Biomedicals Sciences, Tufts University School of Medicine, Boston, MA 02111, USA.

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http://jvi.asm.org/cgi/doi/10.1128/JVI.79.4.2325-2334.2005
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http://dx.doi.org/10.1128/JVI.79.4.2325-2334.2005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC546584PMC
February 2005