Liliane Michalik

Liliane Michalik

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Liliane Michalik

Liliane Michalik

Publications by authors named "Liliane Michalik"

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57Publications

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The Janus face of rosiglitazone.

Oncotarget 2018 Dec 28;9(102):37614-37615. Epub 2018 Dec 28.

Center for Integrative Genomics, University of Lausanne, Lausanne, Switzerland.

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http://dx.doi.org/10.18632/oncotarget.26532DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6340879PMC
December 2018

PPARβ/δ prevents endoplasmic reticulum stress-associated inflammation and insulin resistance in skeletal muscle cells through an AMPK-dependent mechanism.

Diabetologia 2014 Oct 26;57(10):2126-35. Epub 2014 Jul 26.

Department of Pharmacology and Therapeutic Chemistry, Faculty of Pharmacy, University of Barcelona, Diagonal 643, 08028, Barcelona, Spain.

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http://dx.doi.org/10.1007/s00125-014-3331-8DOI Listing
October 2014

PPARβ/δ attenuates palmitate-induced endoplasmic reticulum stress and induces autophagic markers in human cardiac cells.

Int J Cardiol 2014 Jun 8;174(1):110-8. Epub 2014 Apr 8.

Department of Pharmacology and Therapeutic Chemistry, IBUB (Institut de Biomedicina de la Universitat de Barcelona), CIBER de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Faculty of Pharmacy, University of Barcelona, Diagonal 643, Barcelona E-08028, Spain. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01675273140062
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http://dx.doi.org/10.1016/j.ijcard.2014.03.176DOI Listing
June 2014

Tau hyperphosphorylation and increased BACE1 and RAGE levels in the cortex of PPARβ/δ-null mice.

Biochim Biophys Acta 2013 Aug 16;1832(8):1241-8. Epub 2013 Mar 16.

Unitat de Farmacologia, Department de Farmacologia i Química Terapèutica, Facultat de Farmàcia, Universitat de Barcelona, Institut de Biomedicina de la UB, IBUB, Spain.

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http://dx.doi.org/10.1016/j.bbadis.2013.03.006DOI Listing
August 2013

PPARs at the crossroads of lipid signaling and inflammation.

Trends Endocrinol Metab 2012 Jul 14;23(7):351-63. Epub 2012 Jun 14.

Center for Integrative Genomics, National Research Center Frontiers in Genetics, University of Lausanne, Le Génopode, CH-1015 Lausanne, Switzerland.

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http://dx.doi.org/10.1016/j.tem.2012.05.001DOI Listing
July 2012

New insights into the role of PPARs.

Prostaglandins Leukot Essent Fatty Acids 2011 Nov 20;85(5):235-43. Epub 2011 Jul 20.

Center for Integrative Genomics, National Research Center "Frontiers in Genetics", University of Lausanne, Genopode Building, CH-1015 Lausanne, Switzerland.

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http://dx.doi.org/10.1016/j.plefa.2011.04.016DOI Listing
November 2011

PPARs Mediate Lipid Signaling in Inflammation and Cancer.

PPAR Res 2008 21;2008:134059. Epub 2008 Dec 21.

Center for Integrative Genomics, National Research Center Frontiers in Genetics, University of Lausanne, 1015 Lausanne, Switzerland.

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http://dx.doi.org/10.1155/2008/134059DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2606065PMC
July 2011

PPARβ/δ activation blocks lipid-induced inflammatory pathways in mouse heart and human cardiac cells.

Biochim Biophys Acta 2011 Feb 9;1811(2):59-67. Epub 2010 Nov 9.

Department of Pharmacology and Therapeutic Chemistry, Institut de Biomedicina de la Universitat de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1016/j.bbalip.2010.11.002DOI Listing
February 2011

Activation of peroxisome proliferator-activated receptor beta/delta inhibits lipopolysaccharide-induced cytokine production in adipocytes by lowering nuclear factor-kappaB activity via extracellular signal-related kinase 1/2.

Diabetes 2008 Aug 28;57(8):2149-57. Epub 2008 Apr 28.

Pharmacology Unit, Department of Pharmacology and Therapeutic Chemistry, Faculty of Pharmacy, Institut de Biomedicina de la UB (IBUB) and CIBERDEM-Instituto de Salud Carlos III, University of Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.2337/db08-0176DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2494695PMC
August 2008

The nuclear hormone receptor peroxisome proliferator-activated receptor beta/delta potentiates cell chemotactism, polarization, and migration.

Mol Cell Biol 2007 Oct 6;27(20):7161-75. Epub 2007 Aug 6.

Center for Integrative Genomics, National Research Center Frontiers in Genetics, University of Lausanne, CH-1015 Lausanne, Switzerland.

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http://dx.doi.org/10.1128/MCB.00436-07DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2168901PMC
October 2007

Peroxisome proliferator-activated receptors (PPARs) in skin health, repair and disease.

Biochim Biophys Acta 2007 Aug 24;1771(8):991-8. Epub 2007 Feb 24.

Center for Integrative Genomics, National Research Center Frontiers in Genetics, University of Lausanne, Genopode Building, CH-1015 Lausanne, Switzerland.

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http://dx.doi.org/10.1016/j.bbalip.2007.02.004DOI Listing
August 2007

Guiding ligands to nuclear receptors.

Cell 2007 May;129(4):649-51

Center for Integrative Genomics, National Research Center Frontiers in Genetics, University of Lausanne, Switzerland.

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http://dx.doi.org/10.1016/j.cell.2007.05.001DOI Listing
May 2007

Combined simulation and mutagenesis analyses reveal the involvement of key residues for peroxisome proliferator-activated receptor alpha helix 12 dynamic behavior.

J Biol Chem 2007 Mar 2;282(13):9666-77. Epub 2007 Jan 2.

Center for Integrative Genomics and National Research Center Frontiers in Genetics, University of Lausanne, Le Génopode, CH-1015 Lausanne, Switzerland.

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http://dx.doi.org/10.1074/jbc.M610523200DOI Listing
March 2007

Functions of the peroxisome proliferator-activated receptor (PPAR) alpha and beta in skin homeostasis, epithelial repair, and morphogenesis.

J Investig Dermatol Symp Proc 2006 Sep;11(1):30-5

Center for Integrative Genomics, National Research Centre Frontiers in Genetics, University of Lausanne, Le Génopode, Lausanne-Dorigny, Switzerland.

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http://dx.doi.org/10.1038/sj.jidsymp.5650007DOI Listing
September 2006

Reciprocal regulation of brain and muscle Arnt-like protein 1 and peroxisome proliferator-activated receptor alpha defines a novel positive feedback loop in the rodent liver circadian clock.

Mol Endocrinol 2006 Aug 23;20(8):1715-27. Epub 2006 Mar 23.

Structure and Evolution of Nuclear Receptors, Centre National de la Recherche Scientifique (CNRS) Unité Mixte de Recherche 5161, Institut Fédératif de Recherche (IFR) 128 BioSciences Lyon-Gerland, Lyon, France.

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http://dx.doi.org/10.1210/me.2006-0052DOI Listing
August 2006

Transcriptional regulation of metabolism.

Physiol Rev 2006 Apr;86(2):465-514

Center for Integrative Genomics, National Centre of Competence in Research Frontiers in Genetics, University of Lausanne, Lausanne, Switzerland.

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http://www.physiology.org/doi/10.1152/physrev.00025.2005
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http://dx.doi.org/10.1152/physrev.00025.2005DOI Listing
April 2006

From molecular action to physiological outputs: peroxisome proliferator-activated receptors are nuclear receptors at the crossroads of key cellular functions.

Prog Lipid Res 2006 Mar 25;45(2):120-59. Epub 2006 Jan 25.

Center for Integrative Genomics, NCCR Frontiers in Genetics, Le Génopode, University of Lausanne, CH-1015 Lausanne, Switzerland.

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http://linkinghub.elsevier.com/retrieve/pii/S016378270500060
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http://dx.doi.org/10.1016/j.plipres.2005.12.002DOI Listing
March 2006

Involvement of PPAR nuclear receptors in tissue injury and wound repair.

J Clin Invest 2006 Mar;116(3):598-606

Center for Integrative Genomics, National Research Centre Frontiers in Genetics, University of Lausanne, Lausanne, Switzerland.

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http://dx.doi.org/10.1172/JCI27958DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1386118PMC
March 2006

PPARs in diseases: control mechanisms of inflammation.

Curr Med Chem 2005 ;12(25):2995-3009

Center for Integrative Genomics, NCCR Frontiers in Genetics, University of Lausanne, CH-1015 Lausanne, Switzerland.

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http://dx.doi.org/10.2174/092986705774462905DOI Listing
January 2006

Transcriptional repression of peroxisome proliferator-activated receptor beta/delta in murine keratinocytes by CCAAT/enhancer-binding proteins.

J Biol Chem 2005 Nov 15;280(46):38700-10. Epub 2005 Sep 15.

Center for Integrative Genomics, National Center of Competence in Research Frontiers in Genetics, University of Lausanne, CH-1015 Lausanne, Switzerland.

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http://dx.doi.org/10.1074/jbc.M507782200DOI Listing
November 2005

Genetic- or transforming growth factor-beta 1-induced changes in epidermal peroxisome proliferator-activated receptor beta/delta expression dictate wound repair kinetics.

J Biol Chem 2005 May 11;280(18):18163-70. Epub 2005 Feb 11.

Center for Integrative Genomics, National Center of Competence in Research Frontiers in Genetics, University of Lausanne, Lausanne CH-1015, Switzerland.

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http://dx.doi.org/10.1074/jbc.M412829200DOI Listing
May 2005

Kinase signaling cascades that modulate peroxisome proliferator-activated receptors.

Curr Opin Cell Biol 2005 Apr;17(2):216-22

Center for Integrative Genomics, NCCR Frontiers in Genetics, University of Lausanne, Switzerland.

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http://dx.doi.org/10.1016/j.ceb.2005.02.002DOI Listing
April 2005

Peroxisome proliferator-activated receptor beta/delta activation inhibits hypertrophy in neonatal rat cardiomyocytes.

Cardiovasc Res 2005 Mar;65(4):832-41

Pharmacology Unit, Department of Pharmacology and Therapeutic Chemistry, Faculty of Pharmacy, University of Barcelona, Diagonal 643, E-08028 Barcelona, Spain.

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http://dx.doi.org/10.1016/j.cardiores.2004.11.011DOI Listing
March 2005

Decreased expression of peroxisome proliferator-activated receptor alpha and liver fatty acid binding protein after partial hepatectomy of rats and mice.

Liver Int 2005 Feb;25(1):33-40

Research Center for Endocrinology and Metabolism, Sahlgrenska Unbiversity Hospital, Göteborg University, SE-413 45 Göteborg, Sweden.

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http://dx.doi.org/10.1111/j.1478-3231.2004.0998.xDOI Listing
February 2005

Multiple expression control mechanisms of peroxisome proliferator-activated receptors and their target genes.

J Steroid Biochem Mol Biol 2005 Feb;93(2-5):99-105

Center for Integrative Genomics, NCCR Frontiers in Genetics, University of Lausanne, Biology Building, CH-1015 Lausanne, Switzerland.

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http://dx.doi.org/10.1016/j.jsbmb.2004.12.025DOI Listing
February 2005

PPARs as drug targets to modulate inflammatory responses?

Curr Drug Targets Inflamm Allergy 2004 Dec;3(4):361-75

Center for Integrative Genomics, NCCR Frontiers in Genomics, University of Lausanne, CH-1015 Lausanne, Switzerland.

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http://dx.doi.org/10.2174/1568010042634578DOI Listing
December 2004

Functions of peroxisome proliferator-activated receptors (PPAR) in skin homeostasis.

Lipids 2004 Nov;39(11):1093-9

Center for Integrative Genomics, NCCR Frontiers in Genetics, University of Lausanne, CH-1015 Lausanne, Switzerland.

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http://dx.doi.org/10.1007/s11745-004-1335-yDOI Listing
November 2004

Essential role of Smad3 in the inhibition of inflammation-induced PPARbeta/delta expression.

EMBO J 2004 Oct 7;23(21):4211-21. Epub 2004 Oct 7.

Center for Integrative Genomics, NCCR Frontiers in Genetics, University of Lausanne, 1015 Lausanne, Switzerland.

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http://dx.doi.org/10.1038/sj.emboj.7600437DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC524401PMC
October 2004

Be fit or be sick: peroxisome proliferator-activated receptors are down the road.

Mol Endocrinol 2004 Jun 15;18(6):1321-32. Epub 2004 Apr 15.

Center for Integrative Genomics, University of Lausanne, Biology Building, CH-1015 Lausanne-Dorigny, Switzerland.

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http://dx.doi.org/10.1210/me.2004-0088DOI Listing
June 2004

Peroxisome proliferator-activated receptor-beta as a target for wound healing drugs.

Expert Opin Ther Targets 2004 Feb;8(1):39-48

Center for Integrative Genomics, NNCR Frontiers in Genetics, University of Lausanne, Switzerland.

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http://dx.doi.org/10.1517/14728222.8.1.39DOI Listing
February 2004

Impaired expression of NADH dehydrogenase subunit 1 and PPARgamma coactivator-1 in skeletal muscle of ZDF rats: restoration by troglitazone.

J Lipid Res 2004 Jan 16;45(1):113-23. Epub 2003 Oct 16.

Pharmacology Unit, Department of Pharmacology and Therapeutic Chemistry, Faculty of Pharmacy, University of Barcelona, Spain.

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http://dx.doi.org/10.1194/jlr.M300208-JLR200DOI Listing
January 2004

Lack of hypotriglyceridemic effect of gemfibrozil as a consequence of age-related changes in rat liver PPARalpha.

Biochem Pharmacol 2004 Jan;67(1):157-66

Facultad de Farmacia, Unidad de Farmacología y Farmacognosia, Universidad de Barcelona, Avda Diagonal 643, 08028, Barcelona, Spain.

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http://dx.doi.org/10.1016/j.bcp.2003.08.034DOI Listing
January 2004

Peroxisome-proliferator-activated receptors and cancers: complex stories.

Nat Rev Cancer 2004 Jan;4(1):61-70

Center for Integrative Genomics, NCCR Frontiers in Genetics, University of Lausanne, CH-1015 Lausanne, Switzerland.

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http://dx.doi.org/10.1038/nrc1254DOI Listing
January 2004

Peroxisome proliferator-activated receptor (PPAR)-beta as a target for wound healing drugs: what is possible?

Am J Clin Dermatol 2003 ;4(8):523-30

Unité CIG-Sciences, Centre Intégratif de Génomique, Université de Lausanne, Lausanne, Switzerland.

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http://dx.doi.org/10.2165/00128071-200304080-00001DOI Listing
November 2003

The anti-apoptotic role of PPARbeta contributes to efficient skin wound healing.

J Steroid Biochem Mol Biol 2003 Jun;85(2-5):257-65

Center for Integrative Genomics, NCCR Frontiers in Genetics, University of Lausanne, CH-1015 Lausanne, Switzerland.

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http://dx.doi.org/10.1016/s0960-0760(03)00215-2DOI Listing
June 2003

Peroxisome proliferator-activated receptors beta/delta: emerging roles for a previously neglected third family member.

Curr Opin Lipidol 2003 Apr;14(2):129-35

Center for Integrative Genomics, NCCR Frontiers in Genetics, University of Lausanne, CH-1015 Lausanne, Switzerland.

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http://dx.doi.org/10.1097/00041433-200304000-00003DOI Listing
April 2003

PPARbeta regulates vitamin A metabolism-related gene expression in hepatic stellate cells undergoing activation.

J Lipid Res 2003 Feb 16;44(2):280-95. Epub 2002 Nov 16.

Laboratory of Molecular Liver Cell Biology, Vrije Universiteit Brussel, 1090 Brussels, Belgium.

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http://dx.doi.org/10.1194/jlr.M200376-JLR200DOI Listing
February 2003

Peroxisome proliferator-activated receptor-beta signaling contributes to enhanced proliferation of hepatic stellate cells.

Gastroenterology 2003 Jan;124(1):184-201

Laboratory of Molecular Liver Cell Biology, Faculty of Medicine and Pharmacy, Free University of Brussels, Laarbeeklaan 103, 1090 Brussel-Jette, Belgium.

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http://www.cmtc.psu.edu/Papers/Shan_etal_HEPA%20copy.pdf
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http://linkinghub.elsevier.com/retrieve/pii/S001650850350031
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http://dx.doi.org/10.1053/gast.2003.50015DOI Listing
January 2003

A new selective peroxisome proliferator-activated receptor gamma antagonist with antiobesity and antidiabetic activity.

Mol Endocrinol 2002 Nov;16(11):2628-44

Institut de biologie animale, Université de Lausanne, CH-1015 Lausanne, Switzerland.

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http://dx.doi.org/10.1210/me.2002-0036DOI Listing
November 2002

Antiapoptotic role of PPARbeta in keratinocytes via transcriptional control of the Akt1 signaling pathway.

Mol Cell 2002 Oct;10(4):721-33

Institut de Biologie Animale, Université de Lausanne, CH-1015, Lausanne, Switzerland.

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http://dx.doi.org/10.1016/s1097-2765(02)00646-9DOI Listing
October 2002

PPAR expression and function during vertebrate development.

Int J Dev Biol 2002 Jan;46(1):105-14

Institut de Biologie Animale, Université de Lausanne, Switzerland.

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January 2002