Liewei Wang

Liewei Wang

UNVERIFIED PROFILE

Are you Liewei Wang?   Register this Author

Register author
Liewei Wang

Liewei Wang

Publications by authors named "Liewei Wang"

Are you Liewei Wang?   Register this Author

100Publications

2104Reads

23Profile Views

CYP2C9 and CYP2C19: Deep Mutational Scanning and Functional Characterization of Genomic Missense Variants.

Clin Transl Sci 2020 Jul 10;13(4):727-742. Epub 2020 Mar 10.

Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, Minnesota, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/cts.12758DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7359949PMC
July 2020

Regulation of sister chromatid cohesion by nuclear PD-L1.

Cell Res 2020 Jul 29;30(7):590-601. Epub 2020 Apr 29.

Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN, 55905, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41422-020-0315-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7343880PMC
July 2020

Author Correction: Regulation of sister chromatid cohesion by nuclear PD-L1.

Cell Res 2020 Jul 7. Epub 2020 Jul 7.

Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN, 55905, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41422-020-0365-yDOI Listing
July 2020

Single-nucleotide polymorphism biomarkers of adjuvant anastrozole-induced estrogen suppression in early breast cancer.

Pharmacogenet Genomics 2020 Jul 8. Epub 2020 Jul 8.

aDivision of Medical Oncology, Department of Oncology bDivision of Biomedical Statistics and Informatics, Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota cCanadian Cancer Trials Group, Kingston, Ontario, Canada dDepartment of Oncology, Baylor College of Medicine, Houston, Texas eMassachusetts General Hospital Cancer Center, Harvard University, Boston, Massachusetts fDepartment of Breast Oncology, M.D. Anderson Cancer Center, Houston, Texas gBreast Medicine Service, Memorial Sloan Kettering Cancer Center, New York, New York hDivision of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic iPatient advocate, Mayo Clinic Breast Cancer Specialized Program of Research Excellence, Rochester, Minnesota, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/FPC.0000000000000415DOI Listing
July 2020

STK38 promotes ATM activation by acting as a reader of histone H4 ufmylation.

Sci Adv 2020 Jun 3;6(23):eaax8214. Epub 2020 Jun 3.

Division of Oncology, Mayo Clinic, Rochester, MN 55905, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1126/sciadv.aax8214DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7269669PMC
June 2020

Functional genomics based on germline genome-wide association studies of endocrine therapy for breast cancer.

Pharmacogenomics 2020 06 16;21(9):615-625. Epub 2020 Jun 16.

Department of Molecular Pharmacology & Experimental Therapeutics, Mayo Clinic, Rochester, MN 55905, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2217/pgs-2019-0191DOI Listing
June 2020

Sex differences in psychotic and non-psychotic major depressive disorder in a Chinese Han population.

J Affect Disord 2020 May 3;268:55-60. Epub 2020 Mar 3.

CAS Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences, Beijing, China; Department of Psychology, University of Chinese Academy of Sciences, Beijing, China. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jad.2020.03.003DOI Listing
May 2020

Patient-specific multi-omics models and the application in personalized combination therapy.

Future Oncol 2020 May 28. Epub 2020 May 28.

Department of Molecular Pharmacology & Experimental Therapeutics, Mayo Clinic, Rochester, MN 55905, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2217/fon-2020-0119DOI Listing
May 2020

Acylcarnitine metabolomic profiles inform clinically-defined major depressive phenotypes.

J Affect Disord 2020 Mar 30;264:90-97. Epub 2019 Nov 30.

Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, NC, United States; Department of Medicine, Duke University, Durham, NC, United States; Duke Institute of Brain Sciences, Duke University, Durham, NC, United States. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jad.2019.11.122DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7024064PMC
March 2020

Plasma cell-free DNA-based predictors of response to abiraterone acetate/prednisone and prognostic factors in metastatic castration-resistant prostate cancer.

Prostate Cancer Prostatic Dis 2020 Mar 18. Epub 2020 Mar 18.

Division of Oncology, Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41391-020-0224-4DOI Listing
March 2020

Alternating EM algorithm for a bilinear model in isoform quantification from RNA-seq data.

Bioinformatics 2020 02;36(3):805-812

Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm 17177, Sweden.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/bioinformatics/btz640DOI Listing
February 2020

Cell-level somatic mutation detection from single-cell RNA sequencing.

Bioinformatics 2019 11;35(22):4679-4687

Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm 17177, Sweden.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/bioinformatics/btz288DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6853710PMC
November 2019

Pharmacogenomics in Practice.

Clin Pharmacol Ther 2019 11 9;106(5):936-938. Epub 2019 Sep 9.

Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, Minnesota, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/cpt.1600DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6857970PMC
November 2019

Targeting DNA methylation for treating triple-negative breast cancer.

Pharmacogenomics 2019 11;20(16):1151-1157

Department of Molecular Pharmacology & Experimental Therapeutics, Mayo Clinic, Rochester, MN 55905, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2217/pgs-2019-0078DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026764PMC
November 2019

Single Nucleotide Polymorphisms at a Distance from Aryl Hydrocarbon Receptor (AHR) Binding Sites Influence AHR Ligand-Dependent Gene Expression.

Drug Metab Dispos 2019 09 10;47(9):983-994. Epub 2019 Jul 10.

Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics (D.R.N., D.L., H.L., L.W., R.M.W.), Epigenomics Program, Center for Individualized Medicine (J.-H.L., T.O.), Division of Experimental Pathology and Laboratory Medicine, Department of Laboratory Medicine and Pathology (J.-H.L.), Division of Biomedical Statistics and Informatics (Z.Y.), Department of Physiology and Biomedical Engineering (T.O.), and Division of Gastroenterology and Hepatology, Department of Medicine (T.O.), Mayo Clinic, Rochester, Minnesota

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1124/dmd.119.087312DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7184190PMC
September 2019

4-Hydroxytamoxifen enhances sensitivity of estrogen receptor α-positive breast cancer to docetaxel in an estrogen and ZNF423 SNP-dependent fashion.

Breast Cancer Res Treat 2019 Jun 1;175(3):567-578. Epub 2019 Apr 1.

Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10549-019-05194-zDOI Listing
June 2019

Spontaneous murine tumors in the development of patient-derived xenografts: a potential pitfall.

Oncotarget 2019 Jun 11;10(39):3924-3930. Epub 2019 Jun 11.

Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.18632/oncotarget.27001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6570466PMC
June 2019

Pharmacogenomic Next-Generation DNA Sequencing: Lessons from the Identification and Functional Characterization of Variants of Unknown Significance in and .

Drug Metab Dispos 2019 04 11;47(4):425-435. Epub 2019 Feb 11.

Departments of Molecular Pharmacology and Experimental Therapeutics (S.D., I.M., M.-F.H., L.W., R.M.W., J.M.R.) and Health Sciences Research (N.B.L., S.J.B.), Personalized Genomics Laboratory, Department of Laboratory Medicine and Pathology (A.M.M., J.L.B.), and Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic Graduate School of Biomedical Sciences (D.R.N.), Mayo Clinic, Rochester, Minnesota; and Human Genome Sequencing Center, Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas (S.E.S.)

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1124/dmd.118.084269DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423619PMC
April 2019

The lncRNA MIR2052HG regulates ERα levels and aromatase inhibitor resistance through LMTK3 by recruiting EGR1.

Breast Cancer Res 2019 04 3;21(1):47. Epub 2019 Apr 3.

Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN, 55905, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13058-019-1130-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448248PMC
April 2019

UFL1 promotes histone H4 ufmylation and ATM activation.

Nat Commun 2019 03 18;10(1):1242. Epub 2019 Mar 18.

Department of Oncology, Mayo Clinic, Rochester, MN, 55905, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41467-019-09175-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423285PMC
March 2019

Identification of pathways associated with chemosensitivity through network embedding.

PLoS Comput Biol 2019 03 20;15(3):e1006864. Epub 2019 Mar 20.

Department of Computer Science, University of Illinois at Urbana-Champaign, Urbana, Illinois, United States of America.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.pcbi.1006864DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443184PMC
March 2019

The novel function of tumor protein D54 in regulating pyruvate dehydrogenase and metformin cytotoxicity in breast cancer.

Cancer Metab 2019 24;7. Epub 2019 Jan 24.

1Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, 200 First Street SW, Rochester, MN 55905 USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s40170-018-0193-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345044PMC
January 2019

Tyrosine Phosphorylation of Mitochondrial Creatine Kinase 1 Enhances a Druggable Tumor Energy Shuttle Pathway.

Cell Metab 2018 12 30;28(6):833-847.e8. Epub 2018 Aug 30.

Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN 55905, USA; Division of Oncology Research, Mayo Clinic, Rochester, MN 55905, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cmet.2018.08.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6281770PMC
December 2018

Single Nucleotide Polymorphisms (SNPs) Distant from Xenobiotic Response Elements Can Modulate Aryl Hydrocarbon Receptor Function: SNP-Dependent CYP1A1 Induction.

Drug Metab Dispos 2018 09 6;46(9):1372-1381. Epub 2018 Jul 6.

Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics (D.L., S.Q., B.R., L.W., R.M.W.) and Division of Biomedical Statistics and Informatics, Department of Health Sciences Research (K.R.K.), Mayo Clinic, Rochester, Minnesota

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1124/dmd.118.082164DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090174PMC
September 2018

BRCA1/2 Mutations and Bevacizumab in the Neoadjuvant Treatment of Breast Cancer: Response and Prognosis Results in Patients With Triple-Negative Breast Cancer From the GeparQuinto Study.

J Clin Oncol 2018 08 23;36(22):2281-2287. Epub 2018 May 23.

Peter A. Fasching and Matthias Rübner, Erlangen University Hospital, Friedrich-Alexander University of Erlangen-Nuremberg, Erlangen; Sibylle Loibl, Valentina Nekljudova, Karsten E. Weber, and Gunter von Minckwitz, German Breast Group Forschungs, Neu-Isenburg; Christian Schem, University Medical Center Schleswig-Holstein, Kiel; Hans Tesch, Centrum für Hämatologie und Onkologie Bethanien, Frankfurt; Michael Untch, Helios-Klinikum, Berlin-Buch; Jörn Hilfrich, Eilenriede-Klinik, Hannover; Mahdi Rezai, Luisenkrankenhaus; Tanja Fehm, Düsseldorf University Hospital, Heinrich-Heine University of Düsseldorf, Düsseldorf; Bernd Gerber, University of Rostock, Rostock; Serban Dan Costa, Magdeburg University Hospital, Magdeburg; Jens-Uwe Blohmer and Cornelia Liedtke, Charité University Hospital Campus Charité-Mitte, Berlin; Jens Huober, University of Ulm; Brigitte Rack, University Hospital Ulm, Ulm; Volkmar Müller, Hamburg University Hospital, Hamburg, Germany; Chunling Hu, Steven N. Hart, Hermela Shimelis, Raymond Moore, James N. Ingle, and Fergus J. Couch, Mayo Clinic; and Richard M. Weinshilboum and Liewei Wang, Mayo Clinic College of Medicine, Mayo Foundation, Rochester, MN.

View Article

Download full-text PDF

Source
http://ascopubs.org/doi/10.1200/JCO.2017.77.2285
Publisher Site
http://dx.doi.org/10.1200/JCO.2017.77.2285DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6067803PMC
August 2018

Principled multi-omic analysis reveals gene regulatory mechanisms of phenotype variation.

Genome Res 2018 08 13;28(8):1207-1216. Epub 2018 Jun 13.

Department of Computer Science and Institute of Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1101/gr.227066.117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071639PMC
August 2018

Isoform-level gene expression patterns in single-cell RNA-sequencing data.

Bioinformatics 2018 07;34(14):2392-2400

Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/bioinformatics/bty100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6041805PMC
July 2018

HGT-ID: an efficient and sensitive workflow to detect human-viral insertion sites using next-generation sequencing data.

BMC Bioinformatics 2018 07 17;19(1):271. Epub 2018 Jul 17.

Division of Biomedical Statistics and Informatics, Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12859-018-2260-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6050683PMC
July 2018

, a Novel Transcription Factor and a Coregulator of Nuclear Factor B p65: Single Nucleotide Polymorphism and Estrogen Dependence.

J Pharmacol Exp Ther 2018 06 28;365(3):700-710. Epub 2018 Mar 28.

Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics (M.H., E.L.d.R., C.Z., L.W., H.L., R.M.W.), and Division of Medical Oncology, Department of Oncology (J.N.I.), Mayo Clinic, Rochester, Minnesota; Division of Hematology/Oncology, Department of Medicine, Massachusetts General Hospital Cancer Center, Boston, Massachusetts (P.E.G.); Canadian Cancer Trials Group, Kingston, Ontario, Canada (L.E.S.); and RIKEN Center for Integrative Medical Science, Yokohama, Japan (M.K.)

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1124/jpet.118.247718DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5954488PMC
June 2018

Ketamine and ketamine metabolites as novel estrogen receptor ligands: Induction of cytochrome P450 and AMPA glutamate receptor gene expression.

Biochem Pharmacol 2018 06 3;152:279-292. Epub 2018 Apr 3.

Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bcp.2018.03.032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5960634PMC
June 2018

Differential roles of ERRFI1 in EGFR and AKT pathway regulation affect cancer proliferation.

EMBO Rep 2018 03 15;19(3). Epub 2018 Jan 15.

Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN, USA

View Article

Download full-text PDF

Source
http://dx.doi.org/10.15252/embr.201744767DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5835844PMC
March 2018

Pharmacogenomic Discovery to Function and Mechanism: Breast Cancer as a Case Study.

Clin Pharmacol Ther 2018 02 1;103(2):243-252. Epub 2017 Dec 1.

Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, Minnesota, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/cpt.915DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760458PMC
February 2018

Pharmacogenomics: Precision Medicine and Drug Response.

Mayo Clin Proc 2017 11 1;92(11):1711-1722. Epub 2017 Nov 1.

Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.mayocp.2017.09.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5682947PMC
November 2017

SNPs near the cysteine proteinase cathepsin O gene (CTSO) determine tamoxifen sensitivity in ERα-positive breast cancer through regulation of BRCA1.

PLoS Genet 2017 Oct 2;13(10):e1007031. Epub 2017 Oct 2.

Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, Minnesota, United States of America.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.pgen.1007031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5638617PMC
October 2017

Single-Nucleotide Polymorphisms and Estrogen-Mediated Toll-Like Receptor-MYD88-Dependent Nuclear Factor-B Activation: Single-Nucleotide Polymorphism- and Selective Estrogen Receptor Modulator-Dependent Modification of Inflammation and Immune Response.

Mol Pharmacol 2017 08 14;92(2):175-184. Epub 2017 Jun 14.

Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics (M.-F.H., L.W., R.M.W.), Division of Medical Oncology, Department of Oncology (J.N.I.), and Division of Biomedical Statistics and Informatics, Department of Health Sciences Research (K.R.K.), Mayo Clinic, Rochester, Minnesota; Department of Emergency Medicine, Vanderbilt Medical Center, Nashville, Tennessee (T.B.); Division of Hematology/Oncology, Department of Medicine, Massachusetts General Hospital Cancer Center, Boston, Massachusetts (P.E.G.); NCIC Clinical Trials Group, Kingston, Ontario Canada (L.E.S.); and RIKEN Center for Integrative Medical Science, Tsurumi-ku, Yokohama, Japan (T.M., M.K.)

View Article

Download full-text PDF

Source
http://molpharm.aspetjournals.org/lookup/doi/10.1124/mol.117
Publisher Site
http://dx.doi.org/10.1124/mol.117.108340DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5508195PMC
August 2017

Knowledge-guided gene prioritization reveals new insights into the mechanisms of chemoresistance.

Genome Biol 2017 08 11;18(1):153. Epub 2017 Aug 11.

Department of Computer Science and Institute of Genomic Biology, University of Illinois at Urbana-Champaign, 2122 Siebel Center, 201N. Goodwin Ave, Urbana, IL, 61801, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13059-017-1282-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5554409PMC
August 2017

Sirolimus Therapy Is Associated with Elevation in Circulating PCSK9 Levels in Cardiac Transplant Patients.

J Cardiovasc Transl Res 2017 Feb 27;10(1):9-15. Epub 2016 Dec 27.

Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, 200 First Street SW, Rochester, MN, 55905, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s12265-016-9719-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325778PMC
February 2017

Regulation of Serine-Threonine Kinase Akt Activation by NAD-Dependent Deacetylase SIRT7.

Cell Rep 2017 01;18(5):1229-1240

Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN 55905, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.celrep.2017.01.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5298804PMC
January 2017

Genetic variations associated with gemcitabine treatment outcome in pancreatic cancer.

Pharmacogenet Genomics 2016 Dec;26(12):527-537

aDepartment of Oncology bKey Laboratory of Biotechnology of Antibiotics, the National Health and Family Planning Commission (NHFPC), Institute of Medicinal Biotechnology cDepartment of Abdominal Surgery, Cancer Hospital, Peking Union Medical College & Chinese Academy of Medical Sciences, Beijing, China dDepartment of Molecular Pharmacology and Experimental Therapeutics, Division of Clinical Pharmacology eDepartment of Health Sciences Research, Division of Biomedical Statistics and Informatics fDepartment of Oncology, Mayo Clinic, Rochester, Minnesota gDepartment of Biostatistics, University of Kansas Medical Center, Kansas City, Kansas, USA.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5083195PMC
http://dx.doi.org/10.1097/FPC.0000000000000241DOI Listing
December 2016

A network-based phenotype mapping approach to identify genes that modulate drug response phenotypes.

Sci Rep 2016 11 14;6:37003. Epub 2016 Nov 14.

Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic College of Medicine, Rochester, MN 55905, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/srep37003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5107984PMC
November 2016

Beta-Poisson model for single-cell RNA-seq data analyses.

Bioinformatics 2016 07 19;32(14):2128-35. Epub 2016 Apr 19.

Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, 17177 Stockholm, Sweden.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/bioinformatics/btw202DOI Listing
July 2016

Estrogen, SNP-Dependent Chemokine Expression and Selective Estrogen Receptor Modulator Regulation.

Mol Endocrinol 2016 Mar 11;30(3):382-98. Epub 2016 Feb 11.

Division of Clinical Pharmacology (M.-F.H., M.L., L.W., R.M.W.), Department of Molecular Pharmacology and Experimental Therapeutics, Division of Rheumatology (M.-F.H., T.B.), Department of Medicine, Division of Biomedical Statistics and Informatics (K.R.K.), Department of Health Sciences Research, and Division of Medical Oncology (M.P.G., J.N.I.), Department of Oncology, Mayo Clinic, Rochester, Minnesota 55905; Division of Hematology/Oncology (P.E.G.), Department of Medicine, Massachusetts General Hospital Cancer Center, Harvard University, Boston, Massachusetts 02114; National Cancer Institute of Canada Clinical Trials Group (L.E.S.), Kingston, Ontario, Canada K7L 3N6; and RIKEN Center for Integrative Medical Science (M.K.), Yokohama 230-0045, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1210/me.2015-1267DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4771694PMC
March 2016

Measure transcript integrity using RNA-seq data.

BMC Bioinformatics 2016 Feb 3;17:58. Epub 2016 Feb 3.

Division of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, MN, 55905, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12859-016-0922-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4739097PMC
February 2016

Deubiquitination and Activation of AMPK by USP10.

Mol Cell 2016 Feb 11;61(4):614-624. Epub 2016 Feb 11.

Division of Oncology Research, Mayo Clinic, Rochester, MN 55905, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.molcel.2016.01.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4836875PMC
February 2016