Liewei Wang

Liewei Wang

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Publications by authors named "Liewei Wang"

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4-Hydroxytamoxifen enhances sensitivity of estrogen receptor α-positive breast cancer to docetaxel in an estrogen and ZNF423 SNP-dependent fashion.

Breast Cancer Res Treat 2019 Jun 1;175(3):567-578. Epub 2019 Apr 1.

Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN, USA.

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http://dx.doi.org/10.1007/s10549-019-05194-zDOI Listing
June 2019

Spontaneous murine tumors in the development of patient-derived xenografts: a potential pitfall.

Oncotarget 2019 Jun 11;10(39):3924-3930. Epub 2019 Jun 11.

Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN, USA.

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http://dx.doi.org/10.18632/oncotarget.27001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6570466PMC
June 2019

Pharmacogenomic Next-Generation DNA Sequencing: Lessons from the Identification and Functional Characterization of Variants of Unknown Significance in and .

Drug Metab Dispos 2019 Apr 11;47(4):425-435. Epub 2019 Feb 11.

Departments of Molecular Pharmacology and Experimental Therapeutics (S.D., I.M., M.-F.H., L.W., R.M.W., J.M.R.) and Health Sciences Research (N.B.L., S.J.B.), Personalized Genomics Laboratory, Department of Laboratory Medicine and Pathology (A.M.M., J.L.B.), and Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic Graduate School of Biomedical Sciences (D.R.N.), Mayo Clinic, Rochester, Minnesota; and Human Genome Sequencing Center, Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas (S.E.S.)

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http://dx.doi.org/10.1124/dmd.118.084269DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423619PMC
April 2019

The lncRNA MIR2052HG regulates ERα levels and aromatase inhibitor resistance through LMTK3 by recruiting EGR1.

Breast Cancer Res 2019 Apr 3;21(1):47. Epub 2019 Apr 3.

Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN, 55905, USA.

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http://dx.doi.org/10.1186/s13058-019-1130-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448248PMC
April 2019

Cell-level somatic mutation detection from single-cell RNA-sequencing.

Bioinformatics 2019 Apr 26. Epub 2019 Apr 26.

Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1093/bioinformatics/btz288DOI Listing
April 2019

UFL1 promotes histone H4 ufmylation and ATM activation.

Nat Commun 2019 03 18;10(1):1242. Epub 2019 Mar 18.

Department of Oncology, Mayo Clinic, Rochester, MN, 55905, USA.

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http://dx.doi.org/10.1038/s41467-019-09175-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423285PMC
March 2019

Identification of pathways associated with chemosensitivity through network embedding.

PLoS Comput Biol 2019 03 20;15(3):e1006864. Epub 2019 Mar 20.

Department of Computer Science, University of Illinois at Urbana-Champaign, Urbana, Illinois, United States of America.

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http://dx.doi.org/10.1371/journal.pcbi.1006864DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443184PMC
March 2019

The novel function of tumor protein D54 in regulating pyruvate dehydrogenase and metformin cytotoxicity in breast cancer.

Cancer Metab 2019 24;7. Epub 2019 Jan 24.

1Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, 200 First Street SW, Rochester, MN 55905 USA.

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http://dx.doi.org/10.1186/s40170-018-0193-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345044PMC
January 2019

Tyrosine Phosphorylation of Mitochondrial Creatine Kinase 1 Enhances a Druggable Tumor Energy Shuttle Pathway.

Cell Metab 2018 Dec 30;28(6):833-847.e8. Epub 2018 Aug 30.

Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN 55905, USA; Division of Oncology Research, Mayo Clinic, Rochester, MN 55905, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2018.08.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6281770PMC
December 2018

Single Nucleotide Polymorphisms (SNPs) Distant from Xenobiotic Response Elements Can Modulate Aryl Hydrocarbon Receptor Function: SNP-Dependent CYP1A1 Induction.

Drug Metab Dispos 2018 09 6;46(9):1372-1381. Epub 2018 Jul 6.

Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics (D.L., S.Q., B.R., L.W., R.M.W.) and Division of Biomedical Statistics and Informatics, Department of Health Sciences Research (K.R.K.), Mayo Clinic, Rochester, Minnesota

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http://dx.doi.org/10.1124/dmd.118.082164DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090174PMC
September 2018

BRCA1/2 Mutations and Bevacizumab in the Neoadjuvant Treatment of Breast Cancer: Response and Prognosis Results in Patients With Triple-Negative Breast Cancer From the GeparQuinto Study.

J Clin Oncol 2018 Aug 23;36(22):2281-2287. Epub 2018 May 23.

Peter A. Fasching and Matthias Rübner, Erlangen University Hospital, Friedrich-Alexander University of Erlangen-Nuremberg, Erlangen; Sibylle Loibl, Valentina Nekljudova, Karsten E. Weber, and Gunter von Minckwitz, German Breast Group Forschungs, Neu-Isenburg; Christian Schem, University Medical Center Schleswig-Holstein, Kiel; Hans Tesch, Centrum für Hämatologie und Onkologie Bethanien, Frankfurt; Michael Untch, Helios-Klinikum, Berlin-Buch; Jörn Hilfrich, Eilenriede-Klinik, Hannover; Mahdi Rezai, Luisenkrankenhaus; Tanja Fehm, Düsseldorf University Hospital, Heinrich-Heine University of Düsseldorf, Düsseldorf; Bernd Gerber, University of Rostock, Rostock; Serban Dan Costa, Magdeburg University Hospital, Magdeburg; Jens-Uwe Blohmer and Cornelia Liedtke, Charité University Hospital Campus Charité-Mitte, Berlin; Jens Huober, University of Ulm; Brigitte Rack, University Hospital Ulm, Ulm; Volkmar Müller, Hamburg University Hospital, Hamburg, Germany; Chunling Hu, Steven N. Hart, Hermela Shimelis, Raymond Moore, James N. Ingle, and Fergus J. Couch, Mayo Clinic; and Richard M. Weinshilboum and Liewei Wang, Mayo Clinic College of Medicine, Mayo Foundation, Rochester, MN.

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http://ascopubs.org/doi/10.1200/JCO.2017.77.2285
Publisher Site
http://dx.doi.org/10.1200/JCO.2017.77.2285DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6067803PMC
August 2018

Principled multi-omic analysis reveals gene regulatory mechanisms of phenotype variation.

Genome Res 2018 08 13;28(8):1207-1216. Epub 2018 Jun 13.

Department of Computer Science and Institute of Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, USA.

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http://dx.doi.org/10.1101/gr.227066.117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071639PMC
August 2018

Isoform-level gene expression patterns in single-cell RNA-sequencing data.

Bioinformatics 2018 07;34(14):2392-2400

Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1093/bioinformatics/bty100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6041805PMC
July 2018

HGT-ID: an efficient and sensitive workflow to detect human-viral insertion sites using next-generation sequencing data.

BMC Bioinformatics 2018 07 17;19(1):271. Epub 2018 Jul 17.

Division of Biomedical Statistics and Informatics, Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA.

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http://dx.doi.org/10.1186/s12859-018-2260-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6050683PMC
July 2018

, a Novel Transcription Factor and a Coregulator of Nuclear Factor B p65: Single Nucleotide Polymorphism and Estrogen Dependence.

J Pharmacol Exp Ther 2018 Jun 28;365(3):700-710. Epub 2018 Mar 28.

Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics (M.H., E.L.d.R., C.Z., L.W., H.L., R.M.W.), and Division of Medical Oncology, Department of Oncology (J.N.I.), Mayo Clinic, Rochester, Minnesota; Division of Hematology/Oncology, Department of Medicine, Massachusetts General Hospital Cancer Center, Boston, Massachusetts (P.E.G.); Canadian Cancer Trials Group, Kingston, Ontario, Canada (L.E.S.); and RIKEN Center for Integrative Medical Science, Yokohama, Japan (M.K.)

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http://dx.doi.org/10.1124/jpet.118.247718DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5954488PMC
June 2018

Ketamine and ketamine metabolites as novel estrogen receptor ligands: Induction of cytochrome P450 and AMPA glutamate receptor gene expression.

Biochem Pharmacol 2018 06 3;152:279-292. Epub 2018 Apr 3.

Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bcp.2018.03.032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5960634PMC
June 2018

Differential roles of ERRFI1 in EGFR and AKT pathway regulation affect cancer proliferation.

EMBO Rep 2018 03 15;19(3). Epub 2018 Jan 15.

Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN, USA

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http://dx.doi.org/10.15252/embr.201744767DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5835844PMC
March 2018

Pharmacogenomic Discovery to Function and Mechanism: Breast Cancer as a Case Study.

Clin Pharmacol Ther 2018 02 1;103(2):243-252. Epub 2017 Dec 1.

Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, Minnesota, USA.

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http://dx.doi.org/10.1002/cpt.915DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760458PMC
February 2018

Pharmacogenomics: Precision Medicine and Drug Response.

Mayo Clin Proc 2017 11 1;92(11):1711-1722. Epub 2017 Nov 1.

Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN.

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http://dx.doi.org/10.1016/j.mayocp.2017.09.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5682947PMC
November 2017

SNPs near the cysteine proteinase cathepsin O gene (CTSO) determine tamoxifen sensitivity in ERα-positive breast cancer through regulation of BRCA1.

PLoS Genet 2017 Oct 2;13(10):e1007031. Epub 2017 Oct 2.

Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, Minnesota, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1007031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5638617PMC
October 2017

Single-Nucleotide Polymorphisms and Estrogen-Mediated Toll-Like Receptor-MYD88-Dependent Nuclear Factor-B Activation: Single-Nucleotide Polymorphism- and Selective Estrogen Receptor Modulator-Dependent Modification of Inflammation and Immune Response.

Mol Pharmacol 2017 08 14;92(2):175-184. Epub 2017 Jun 14.

Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics (M.-F.H., L.W., R.M.W.), Division of Medical Oncology, Department of Oncology (J.N.I.), and Division of Biomedical Statistics and Informatics, Department of Health Sciences Research (K.R.K.), Mayo Clinic, Rochester, Minnesota; Department of Emergency Medicine, Vanderbilt Medical Center, Nashville, Tennessee (T.B.); Division of Hematology/Oncology, Department of Medicine, Massachusetts General Hospital Cancer Center, Boston, Massachusetts (P.E.G.); NCIC Clinical Trials Group, Kingston, Ontario Canada (L.E.S.); and RIKEN Center for Integrative Medical Science, Tsurumi-ku, Yokohama, Japan (T.M., M.K.)

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http://molpharm.aspetjournals.org/lookup/doi/10.1124/mol.117
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http://dx.doi.org/10.1124/mol.117.108340DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5508195PMC
August 2017

Knowledge-guided gene prioritization reveals new insights into the mechanisms of chemoresistance.

Genome Biol 2017 08 11;18(1):153. Epub 2017 Aug 11.

Department of Computer Science and Institute of Genomic Biology, University of Illinois at Urbana-Champaign, 2122 Siebel Center, 201N. Goodwin Ave, Urbana, IL, 61801, USA.

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http://dx.doi.org/10.1186/s13059-017-1282-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5554409PMC
August 2017

Sirolimus Therapy Is Associated with Elevation in Circulating PCSK9 Levels in Cardiac Transplant Patients.

J Cardiovasc Transl Res 2017 Feb 27;10(1):9-15. Epub 2016 Dec 27.

Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, 200 First Street SW, Rochester, MN, 55905, USA.

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http://dx.doi.org/10.1007/s12265-016-9719-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325778PMC
February 2017

Regulation of Serine-Threonine Kinase Akt Activation by NAD-Dependent Deacetylase SIRT7.

Cell Rep 2017 01;18(5):1229-1240

Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN 55905, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2017.01.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5298804PMC
January 2017

Genetic variations associated with gemcitabine treatment outcome in pancreatic cancer.

Pharmacogenet Genomics 2016 Dec;26(12):527-537

aDepartment of Oncology bKey Laboratory of Biotechnology of Antibiotics, the National Health and Family Planning Commission (NHFPC), Institute of Medicinal Biotechnology cDepartment of Abdominal Surgery, Cancer Hospital, Peking Union Medical College & Chinese Academy of Medical Sciences, Beijing, China dDepartment of Molecular Pharmacology and Experimental Therapeutics, Division of Clinical Pharmacology eDepartment of Health Sciences Research, Division of Biomedical Statistics and Informatics fDepartment of Oncology, Mayo Clinic, Rochester, Minnesota gDepartment of Biostatistics, University of Kansas Medical Center, Kansas City, Kansas, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5083195PMC
http://dx.doi.org/10.1097/FPC.0000000000000241DOI Listing
December 2016

Using EHR-Linked Biobank Data to Study Metformin Pharmacogenomics.

Stud Health Technol Inform 2015 ;210:914-8

Mayo Clinic, Department of Health of Sciences Research.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5051541PMC
November 2016

A network-based phenotype mapping approach to identify genes that modulate drug response phenotypes.

Sci Rep 2016 11 14;6:37003. Epub 2016 Nov 14.

Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic College of Medicine, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1038/srep37003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5107984PMC
November 2016

Beta-Poisson model for single-cell RNA-seq data analyses.

Bioinformatics 2016 07 19;32(14):2128-35. Epub 2016 Apr 19.

Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, 17177 Stockholm, Sweden.

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http://dx.doi.org/10.1093/bioinformatics/btw202DOI Listing
July 2016

Estrogen, SNP-Dependent Chemokine Expression and Selective Estrogen Receptor Modulator Regulation.

Mol Endocrinol 2016 Mar 11;30(3):382-98. Epub 2016 Feb 11.

Division of Clinical Pharmacology (M.-F.H., M.L., L.W., R.M.W.), Department of Molecular Pharmacology and Experimental Therapeutics, Division of Rheumatology (M.-F.H., T.B.), Department of Medicine, Division of Biomedical Statistics and Informatics (K.R.K.), Department of Health Sciences Research, and Division of Medical Oncology (M.P.G., J.N.I.), Department of Oncology, Mayo Clinic, Rochester, Minnesota 55905; Division of Hematology/Oncology (P.E.G.), Department of Medicine, Massachusetts General Hospital Cancer Center, Harvard University, Boston, Massachusetts 02114; National Cancer Institute of Canada Clinical Trials Group (L.E.S.), Kingston, Ontario, Canada K7L 3N6; and RIKEN Center for Integrative Medical Science (M.K.), Yokohama 230-0045, Japan.

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http://dx.doi.org/10.1210/me.2015-1267DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4771694PMC
March 2016

Measure transcript integrity using RNA-seq data.

BMC Bioinformatics 2016 Feb 3;17:58. Epub 2016 Feb 3.

Division of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, MN, 55905, USA.

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http://dx.doi.org/10.1186/s12859-016-0922-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4739097PMC
February 2016

Deubiquitination and Activation of AMPK by USP10.

Mol Cell 2016 Feb 11;61(4):614-624. Epub 2016 Feb 11.

Division of Oncology Research, Mayo Clinic, Rochester, MN 55905, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2016.01.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4836875PMC
February 2016

Bora downregulation results in radioresistance by promoting repair of double strand breaks.

PLoS One 2015 5;10(3):e0119208. Epub 2015 Mar 5.

Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, Minnesota, 55905, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0119208PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351037PMC
January 2016

In vitro human cell line models to predict clinical response to anticancer drugs.

Pharmacogenomics 2015 ;16(3):273-85

Division of Clinical Pharmacology, Department of Molecular Pharmacology & Experimental Therapeutics, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA.

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http://dx.doi.org/10.2217/pgs.14.170DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4358765PMC
November 2015

DBC1 functions as a tumor suppressor by regulating p53 stability.

Cell Rep 2015 Mar 26;10(8):1324-34. Epub 2015 Feb 26.

Division of Oncology Research, Mayo Clinic, Rochester, MN 55905, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2015.01.066DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351187PMC
March 2015

PharmGKB summary: gemcitabine pathway.

Pharmacogenet Genomics 2014 Nov;24(11):564-74

Departments of aGenetics bBioengineering, Stanford University, Stanford, California, USA cDepartment of Pharmacotherapy and Translational Research dCenter for Pharmacogenomics, College of Pharmacy, University of Florida, Gainesville, Florida eDepartment of Molecular Pharmacology & Experimental Therapeutics, Division of Clinical Pharmacology, Mayo Clinic, Rochester, Minnesota, USA.

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http://dx.doi.org/10.1097/FPC.0000000000000086DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4189987PMC
November 2014

Snail contributes to the maintenance of stem cell-like phenotype cells in human pancreatic cancer.

PLoS One 2014 29;9(1):e87409. Epub 2014 Jan 29.

Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, Minnesota, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0087409PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3906155PMC
October 2014

Aromatase inhibitor-associated bone fractures: a case-cohort GWAS and functional genomics.

Mol Endocrinol 2014 Oct 22;28(10):1740-51. Epub 2014 Aug 22.

Division of Clinical Pharmacology (M.L., L.W., R.M.W.), Department of Molecular Pharmacology and Experimental Therapeutics; Departments of Oncology (J.N.I.) and Health Sciences Research (A.B., G.D.J., E.E.C., D.J.S.); and Division of Endocrinology (S.K.), Mayo Clinic, Rochester, Minnesota 55905; Massachusetts General Hospital (P.E.G.), Harvard University, Boston, Massachusetts 02114; Rikagaku Kenkyūsho Center for Integrative Medical Science (M.K., Y.F.), Yokohama, Japan 230-0045; School of Medicine (Y.N.), Chicago University, Chicago, Illinois 60637; National Cancer Institute of Canada Clinical Trials Group (J.-A.W.C., L.E.S.), Kingston, Ontario, Canada K7L 3N6; and Division of Oncology (M.J.E.), Department of Medicine, Washington University School of Medicine, St Louis, Missouri 63110.

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http://dx.doi.org/10.1210/me.2014-1147DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4179631PMC
October 2014

Metformin pharmacogenomics: biomarkers to mechanisms.

Diabetes 2014 Aug;63(8):2609-10

Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Mayo Clinic College of Medicine, Rochester, MN

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http://dx.doi.org/10.2337/db14-0609DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4113071PMC
August 2014

AMPK regulates histone H2B O-GlcNAcylation.

Nucleic Acids Res 2014 May 1;42(9):5594-604. Epub 2014 Apr 1.

State Key Laboratory of Proteomics, Beijing Proteome Research Center, Beijing Institute of Radiation Medicine, Beijing 100850, China

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http://dx.doi.org/10.1093/nar/gku236DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4027166PMC
May 2014

Thiopurine pharmacogenomics: association of SNPs with clinical response and functional validation of candidate genes.

Pharmacogenomics 2014 Mar;15(4):433-47

Division of Clinical Pharmacology, Department of Molecular Pharmacology & Experimental Therapeutics, Mayo Clinic, Rochester, MN 55905, USA.

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http://dx.doi.org/10.2217/pgs.13.226DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4027966PMC
March 2014

Genome-wide meta-analysis of homocysteine and methionine metabolism identifies five one carbon metabolism loci and a novel association of ALDH1L1 with ischemic stroke.

PLoS Genet 2014 Mar 20;10(3):e1004214. Epub 2014 Mar 20.

Center for Public Health Genomics, University of Virginia, Charlottesville, Virginia, United States of America; Department of Medicine, University of Virginia, Charlottesville, Virginia, United States of America; Department of Biochemistry and Molecular Genetics, University of Virginia, Charlottesville, Virginia, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1004214DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3961178PMC
March 2014

Discovery of genetic biomarkers contributing to variation in drug response of cytidine analogues using human lymphoblastoid cell lines.

BMC Genomics 2014 Feb 1;15:93. Epub 2014 Feb 1.

Division of Biomedical Statistics and Informatics, Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, USA.

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http://dx.doi.org/10.1186/1471-2164-15-93DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3930546PMC
February 2014