Publications by authors named "Lieselotte Vande Walle"

31Publications

Therapeutic modulation of inflammasome pathways.

Immunol Rev 2020 Sep 7;297(1):123-138. Epub 2020 Aug 7.

Laboratory of Medical Innate Immunity, Department of Internal Medicine and Pediatrics, Ghent University, Ghent, Belgium.

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http://dx.doi.org/10.1111/imr.12908DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7497261PMC
September 2020

Snapshot of a Deadly Embrace: The Caspase-1-GSDMD Interface.

Immunity 2020 Jul;53(1):6-8

Laboratory of Medical Innate Immunity, Department of Internal Medicine and Pediatrics, Ghent University, B-9000 Ghent, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2020.06.019DOI Listing
July 2020

Pyroptosis.

Curr Biol 2016 07;26(13):R568-R572

NOD-like receptor and Inflammasome Laboratory, Inflammation Research Center, VIB, Technologiepark 927, Zwijnaarde, B-9052, Belgium; Department of Internal Medicine, Ghent University, Ghent, B-9000, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.cub.2016.02.019DOI Listing
July 2016

Flagellin-induced NLRC4 phosphorylation primes the inflammasome for activation by NAIP5.

Proc Natl Acad Sci U S A 2015 Feb 20;112(5):1541-6. Epub 2015 Jan 20.

Department of Medical Protein Research, VIB, Ghent B-9000, Belgium; Department of Biochemistry, Ghent University, Ghent B-9000, Belgium;

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http://dx.doi.org/10.1073/pnas.1417945112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4321312PMC
February 2015

Sensing the enemy within: how macrophages detect intracellular Gram-negative bacteria.

Trends Biochem Sci 2014 Dec 4;39(12):574-6. Epub 2014 Nov 4.

Department of Medical Protein Research, VIB, Ghent, B-9000, Belgium; Department of Biochemistry, Ghent University, Ghent, B-9000, Belgium. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09680004140018
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http://dx.doi.org/10.1016/j.tibs.2014.10.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4247376PMC
December 2014

Activation of the NLRP1b inflammasome independently of ASC-mediated caspase-1 autoproteolysis and speck formation.

Nat Commun 2014 ;5:3209

1] Department of Medical Protein Research, VIB, Ghent B-9000, Belgium [2] Department of Biochemistry, Ghent University, Ghent B-9000, Belgium [3].

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http://www.nature.com/articles/ncomms4209
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http://dx.doi.org/10.1038/ncomms4209DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3926011PMC
October 2015

The small GTPase Arf6 is essential for the Tram/Trif pathway in TLR4 signaling.

J Biol Chem 2014 Jan 2;289(3):1364-76. Epub 2013 Dec 2.

From the Department of Medical Protein Research, Cytokine Receptor Lab, VIB, Ghent B-9000, Belgium.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M113.499194
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http://dx.doi.org/10.1074/jbc.M113.499194DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3894321PMC
January 2014

Addendum: defective Dock2 expression in a subset of ASC-deficient mouse lines.

Nat Immunol 2012 Jul;13(7):701-2

Department of Immunology St. Jude Children’s Research Hospital, Memphis, Tennessee, USA.

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http://dx.doi.org/10.1038/ni.2389DOI Listing
July 2012

Non-canonical inflammasome activation targets caspase-11.

Nature 2011 Oct 16;479(7371):117-21. Epub 2011 Oct 16.

Department of Physiological Chemistry, Genentech Inc., South San Francisco, California 94080, USA.

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http://dx.doi.org/10.1038/nature10558DOI Listing
October 2011

Deregulated inflammasome signaling in disease.

Immunol Rev 2011 Sep;243(1):163-73

Department of Biochemistry, Ghent University, Ghent, Belgium.

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http://dx.doi.org/10.1111/j.1600-065X.2011.01042.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3170132PMC
September 2011

HMGB1 release by inflammasomes.

Virulence 2011 Mar-Apr;2(2):162-5. Epub 2011 Mar 1.

Department of Biochemistry, Ghent University, Ghent, Belgium.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3265758PMC
http://dx.doi.org/10.4161/viru.2.2.15480DOI Listing
August 2011

Inflammasome-dependent release of the alarmin HMGB1 in endotoxemia.

J Immunol 2010 Oct 27;185(7):4385-92. Epub 2010 Aug 27.

Department of Physiological Chemistry, Genentech, South San Francisco, CA 94080, USA.

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http://dx.doi.org/10.4049/jimmunol.1000803DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3428148PMC
October 2010

Caspase-mediated cleavage of the exosome subunit PM/Scl-75 during apoptosis.

Arthritis Res Ther 2007 ;9(1):R12

Department of Biomolecular Chemistry, Nijmegen Center for Molecular Life Sciences, Institute for Molecules and Materials, Radboud University Nijmegen, Geert Grooteplein 26-28, Nijmegen, 6525 GA, The Netherlands.

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http://dx.doi.org/10.1186/ar2119DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1860071PMC
April 2007

Proteome-wide Identification of HtrA2/Omi Substrates.

J Proteome Res 2007 Mar 1;6(3):1006-15. Epub 2007 Feb 1.

Department of Molecular Biomedical Research, VIB, 9052, Ghent, Belgium.

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http://dx.doi.org/10.1021/pr060510dDOI Listing
March 2007

A novel caspase-2 complex containing TRAF2 and RIP1.

J Biol Chem 2005 Feb 8;280(8):6923-32. Epub 2004 Dec 8.

Unit of Molecular Signalling and Cell Death, Department for Molecular Biomedical Research, Ghent University and Flemish Interuniversity Institute for Biotechnology, Technologiepark 927, Zwijnaarde B-9052, Belgium.

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http://www.jbc.org/content/280/8/6923.full.pdf
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http://www.jbc.org/content/early/2004/12/08/jbc.M411180200.f
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http://www.jbc.org/cgi/doi/10.1074/jbc.M411180200
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http://dx.doi.org/10.1074/jbc.M411180200DOI Listing
February 2005

Toxic proteins released from mitochondria in cell death.

Oncogene 2004 Apr;23(16):2861-74

Department for Molecular Biomedical Research, VIB and Ghent University, Fiers-Shell-Van Montagu Building, Ghent B9052, Belgium.

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http://dx.doi.org/10.1038/sj.onc.1207523DOI Listing
April 2004