Liesbeth Vandenput

Liesbeth Vandenput

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Liesbeth Vandenput

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Evidence of a Causal Effect of Estradiol on Fracture Risk in Men.

J Clin Endocrinol Metab 2019 Feb;104(2):433-442

Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

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http://dx.doi.org/10.1210/jc.2018-00934DOI Listing
February 2019

Disentangling the genetics of lean mass.

Authors:
David Karasik M Carola Zillikens Yi-Hsiang Hsu Ali Aghdassi Kristina Akesson Najaf Amin Inês Barroso David A Bennett Lars Bertram Murielle Bochud Ingrid B Borecki Linda Broer Aron S Buchman Liisa Byberg Harry Campbell Natalia Campos-Obando Jane A Cauley Peggy M Cawthon John C Chambers Zhao Chen Nam H Cho Hyung Jin Choi Wen-Chi Chou Steven R Cummings Lisette C P G M de Groot Phillip L De Jager Ilja Demuth Luda Diatchenko Michael J Econs Gudny Eiriksdottir Anke W Enneman Joel Eriksson Johan G Eriksson Karol Estrada Daniel S Evans Mary F Feitosa Mao Fu Christian Gieger Harald Grallert Vilmundur Gudnason Launer J Lenore Caroline Hayward Albert Hofman Georg Homuth Kim M Huffman Lise B Husted Thomas Illig Erik Ingelsson Till Ittermann John-Olov Jansson Toby Johnson Reiner Biffar Joanne M Jordan Antti Jula Magnus Karlsson Kay-Tee Khaw Tuomas O Kilpeläinen Norman Klopp Jacqueline S L Kloth Daniel L Koller Jaspal S Kooner William E Kraus Stephen Kritchevsky Zoltán Kutalik Teemu Kuulasmaa Johanna Kuusisto Markku Laakso Jari Lahti Thomas Lang Bente L Langdahl Markus M Lerch Joshua R Lewis Christina Lill Lars Lind Cecilia Lindgren Yongmei Liu Gregory Livshits Östen Ljunggren Ruth J F Loos Mattias Lorentzon Jian'an Luan Robert N Luben Ida Malkin Fiona E McGuigan Carolina Medina-Gomez Thomas Meitinger Håkan Melhus Dan Mellström Karl Michaëlsson Braxton D Mitchell Andrew P Morris Leif Mosekilde Maria Nethander Anne B Newman Jeffery R O'Connell Ben A Oostra Eric S Orwoll Aarno Palotie Munro Peacock Markus Perola Annette Peters Richard L Prince Bruce M Psaty Katri Räikkönen Stuart H Ralston Samuli Ripatti Fernando Rivadeneira John A Robbins Jerome I Rotter Igor Rudan Veikko Salomaa Suzanne Satterfield Sabine Schipf Chan Soo Shin Albert V Smith Shad B Smith Nicole Soranzo Timothy D Spector Alena Stancáková Kari Stefansson Elisabeth Steinhagen-Thiessen Lisette Stolk Elizabeth A Streeten Unnur Styrkarsdottir Karin M A Swart Patricia Thompson Cynthia A Thomson Gudmar Thorleifsson Unnur Thorsteinsdottir Emmi Tikkanen Gregory J Tranah André G Uitterlinden Cornelia M van Duijn Natasja M van Schoor Liesbeth Vandenput Peter Vollenweider Henry Völzke Jean Wactawski-Wende Mark Walker Nicholas J Wareham Dawn Waterworth Michael N Weedon H-Erich Wichmann Elisabeth Widen Frances M K Williams James F Wilson Nicole C Wright Laura M Yerges-Armstrong Lei Yu Weihua Zhang Jing Hua Zhao Yanhua Zhou Carrie M Nielson Tamara B Harris Serkalem Demissie Douglas P Kiel Claes Ohlsson

Am J Clin Nutr 2019 Feb;109(2):276-287

Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

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http://dx.doi.org/10.1093/ajcn/nqy272DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6500901PMC
February 2019

Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders.

Authors:
Symen Ligthart Ahmad Vaez Urmo Võsa Maria G Stathopoulou Paul S de Vries Bram P Prins Peter J Van der Most Toshiko Tanaka Elnaz Naderi Lynda M Rose Ying Wu Robert Karlsson Maja Barbalic Honghuang Lin René Pool Gu Zhu Aurélien Macé Carlo Sidore Stella Trompet Massimo Mangino Maria Sabater-Lleal John P Kemp Ali Abbasi Tim Kacprowski Niek Verweij Albert V Smith Tao Huang Carola Marzi Mary F Feitosa Kurt K Lohman Marcus E Kleber Yuri Milaneschi Christian Mueller Mahmudul Huq Efthymia Vlachopoulou Leo-Pekka Lyytikäinen Christopher Oldmeadow Joris Deelen Markus Perola Jing Hua Zhao Bjarke Feenstra Marzyeh Amini Jari Lahti Katharina E Schraut Myriam Fornage Bhoom Suktitipat Wei-Min Chen Xiaohui Li Teresa Nutile Giovanni Malerba Jian'an Luan Tom Bak Nicholas Schork Fabiola Del Greco M Elisabeth Thiering Anubha Mahajan Riccardo E Marioni Evelin Mihailov Joel Eriksson Ayse Bilge Ozel Weihua Zhang Maria Nethander Yu-Ching Cheng Stella Aslibekyan Wei Ang Ilaria Gandin Loïc Yengo Laura Portas Charles Kooperberg Edith Hofer Kumar B Rajan Claudia Schurmann Wouter den Hollander Tarunveer S Ahluwalia Jing Zhao Harmen H M Draisma Ian Ford Nicholas Timpson Alexander Teumer Hongyan Huang Simone Wahl YongMei Liu Jie Huang Hae-Won Uh Frank Geller Peter K Joshi Lisa R Yanek Elisabetta Trabetti Benjamin Lehne Diego Vozzi Marie Verbanck Ginevra Biino Yasaman Saba Ingrid Meulenbelt Jeff R O'Connell Markku Laakso Franco Giulianini Patrik K E Magnusson Christie M Ballantyne Jouke Jan Hottenga Grant W Montgomery Fernando Rivadineira Rico Rueedi Maristella Steri Karl-Heinz Herzig David J Stott Cristina Menni Mattias Frånberg Beate St Pourcain Stephan B Felix Tune H Pers Stephan J L Bakker Peter Kraft Annette Peters Dhananjay Vaidya Graciela Delgado Johannes H Smit Vera Großmann Juha Sinisalo Ilkka Seppälä Stephen R Williams Elizabeth G Holliday Matthijs Moed Claudia Langenberg Katri Räikkönen Jingzhong Ding Harry Campbell Michele M Sale Yii-Der I Chen Alan L James Daniela Ruggiero Nicole Soranzo Catharina A Hartman Erin N Smith Gerald S Berenson Christian Fuchsberger Dena Hernandez Carla M T Tiesler Vilmantas Giedraitis David Liewald Krista Fischer Dan Mellström Anders Larsson Yunmei Wang William R Scott Matthias Lorentzon John Beilby Kathleen A Ryan Craig E Pennell Dragana Vuckovic Beverly Balkau Maria Pina Concas Reinhold Schmidt Carlos F Mendes de Leon Erwin P Bottinger Margreet Kloppenburg Lavinia Paternoster Michael Boehnke A W Musk Gonneke Willemsen David M Evans Pamela A F Madden Mika Kähönen Zoltán Kutalik Magdalena Zoledziewska Ville Karhunen Stephen B Kritchevsky Naveed Sattar Genevieve Lachance Robert Clarke Tamara B Harris Olli T Raitakari John R Attia Diana van Heemst Eero Kajantie Rossella Sorice Giovanni Gambaro Robert A Scott Andrew A Hicks Luigi Ferrucci Marie Standl Cecilia M Lindgren John M Starr Magnus Karlsson Lars Lind Jun Z Li John C Chambers Trevor A Mori Eco J C N de Geus Andrew C Heath Nicholas G Martin Juha Auvinen Brendan M Buckley Anton J M de Craen Melanie Waldenberger Konstantin Strauch Thomas Meitinger Rodney J Scott Mark McEvoy Marian Beekman Cristina Bombieri Paul M Ridker Karen L Mohlke Nancy L Pedersen Alanna C Morrison Dorret I Boomsma John B Whitfield David P Strachan Albert Hofman Peter Vollenweider Francesco Cucca Marjo-Riitta Jarvelin J Wouter Jukema Tim D Spector Anders Hamsten Tanja Zeller André G Uitterlinden Matthias Nauck Vilmundur Gudnason Lu Qi Harald Grallert Ingrid B Borecki Jerome I Rotter Winfried März Philipp S Wild Marja-Liisa Lokki Michael Boyle Veikko Salomaa Mads Melbye Johan G Eriksson James F Wilson Brenda W J H Penninx Diane M Becker Bradford B Worrall Greg Gibson Ronald M Krauss Marina Ciullo Gianluigi Zaza Nicholas J Wareham Albertine J Oldehinkel Lyle J Palmer Sarah S Murray Peter P Pramstaller Stefania Bandinelli Joachim Heinrich Erik Ingelsson Ian J Deary Reedik Mägi Liesbeth Vandenput Pim van der Harst Karl C Desch Jaspal S Kooner Claes Ohlsson Caroline Hayward Terho Lehtimäki Alan R Shuldiner Donna K Arnett Lawrence J Beilin Antonietta Robino Philippe Froguel Mario Pirastu Tine Jess Wolfgang Koenig Ruth J F Loos Denis A Evans Helena Schmidt George Davey Smith P Eline Slagboom Gudny Eiriksdottir Andrew P Morris Bruce M Psaty Russell P Tracy Ilja M Nolte Eric Boerwinkle Sophie Visvikis-Siest Alex P Reiner Myron Gross Joshua C Bis Lude Franke Oscar H Franco Emelia J Benjamin Daniel I Chasman Josée Dupuis Harold Snieder Abbas Dehghan Behrooz Z Alizadeh

Am J Hum Genet 2018 11;103(5):691-706

Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen 9700 RB, the Netherlands. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00029297183032
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http://dx.doi.org/10.1016/j.ajhg.2018.09.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218410PMC
November 2018

Serum DHEA and Its Sulfate Are Associated With Incident Fall Risk in Older Men: The MrOS Sweden Study.

J Bone Miner Res 2018 Jul 10;33(7):1227-1232. Epub 2018 Apr 10.

Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

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http://dx.doi.org/10.1002/jbmr.3418DOI Listing
July 2018

Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels.

Authors:
Xia Jiang Paul F O'Reilly Hugues Aschard Yi-Hsiang Hsu J Brent Richards Josée Dupuis Erik Ingelsson David Karasik Stefan Pilz Diane Berry Bryan Kestenbaum Jusheng Zheng Jianan Luan Eleni Sofianopoulou Elizabeth A Streeten Demetrius Albanes Pamela L Lutsey Lu Yao Weihong Tang Michael J Econs Henri Wallaschofski Henry Völzke Ang Zhou Chris Power Mark I McCarthy Erin D Michos Eric Boerwinkle Stephanie J Weinstein Neal D Freedman Wen-Yi Huang Natasja M Van Schoor Nathalie van der Velde Lisette C P G M de Groot Anke Enneman L Adrienne Cupples Sarah L Booth Ramachandran S Vasan Ching-Ti Liu Yanhua Zhou Samuli Ripatti Claes Ohlsson Liesbeth Vandenput Mattias Lorentzon Johan G Eriksson M Kyla Shea Denise K Houston Stephen B Kritchevsky Yongmei Liu Kurt K Lohman Luigi Ferrucci Munro Peacock Christian Gieger Marian Beekman Eline Slagboom Joris Deelen Diana van Heemst Marcus E Kleber Winfried März Ian H de Boer Alexis C Wood Jerome I Rotter Stephen S Rich Cassianne Robinson-Cohen Martin den Heijer Marjo-Riitta Jarvelin Alana Cavadino Peter K Joshi James F Wilson Caroline Hayward Lars Lind Karl Michaëlsson Stella Trompet M Carola Zillikens Andre G Uitterlinden Fernando Rivadeneira Linda Broer Lina Zgaga Harry Campbell Evropi Theodoratou Susan M Farrington Maria Timofeeva Malcolm G Dunlop Ana M Valdes Emmi Tikkanen Terho Lehtimäki Leo-Pekka Lyytikäinen Mika Kähönen Olli T Raitakari Vera Mikkilä M Arfan Ikram Naveed Sattar J Wouter Jukema Nicholas J Wareham Claudia Langenberg Nita G Forouhi Thomas E Gundersen Kay-Tee Khaw Adam S Butterworth John Danesh Timothy Spector Thomas J Wang Elina Hyppönen Peter Kraft Douglas P Kiel

Nat Commun 2018 01 17;9(1):260. Epub 2018 Jan 17.

Institute for Aging Research, Hebrew SeniorLife, 1200 Centre Street, Boston, MA, 02131, USA.

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http://dx.doi.org/10.1038/s41467-017-02662-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5772647PMC
January 2018

Erratum: Large meta-analysis of genome-wide association studies identifies five loci for lean body mass.

Authors:
M Carola Zillikens Serkalem Demissie Yi-Hsiang Hsu Laura M Yerges-Armstrong Wen-Chi Chou Lisette Stolk Gregory Livshits Linda Broer Toby Johnson Daniel L Koller Zoltán Kutalik Jian'an Luan Ida Malkin Janina S Ried Albert V Smith Gudmar Thorleifsson Liesbeth Vandenput Jing Hua Zhao Weihua Zhang Ali Aghdassi Kristina Åkesson Najaf Amin Leslie J Baier Inês Barroso David A Bennett Lars Bertram Rainer Biffar Murielle Bochud Michael Boehnke Ingrid B Borecki Aron S Buchman Liisa Byberg Harry Campbell Natalia Campos Obanda Jane A Cauley Peggy M Cawthon Henna Cederberg Zhao Chen Nam H Cho Hyung Jin Choi Melina Claussnitzer Francis Collins Steven R Cummings Philip L De Jager Ilja Demuth Rosalie A M Dhonukshe-Rutten Luda Diatchenko Gudny Eiriksdottir Anke W Enneman Mike Erdos Johan G Eriksson Joel Eriksson Karol Estrada Daniel S Evans Mary F Feitosa Mao Fu Melissa Garcia Christian Gieger Thomas Girke Nicole L Glazer Harald Grallert Jagvir Grewal Bok-Ghee Han Robert L Hanson Caroline Hayward Albert Hofman Eric P Hoffman Georg Homuth Wen-Chi Hsueh Monica J Hubal Alan Hubbard Kim M Huffman Lise B Husted Thomas Illig Erik Ingelsson Till Ittermann John-Olov Jansson Joanne M Jordan Antti Jula Magnus Karlsson Kay-Tee Khaw Tuomas O Kilpeläinen Norman Klopp Jacqueline S L Kloth Heikki A Koistinen William E Kraus Stephen Kritchevsky Teemu Kuulasmaa Johanna Kuusisto Markku Laakso Jari Lahti Thomas Lang Bente L Langdahl Lenore J Launer Jong-Young Lee Markus M Lerch Joshua R Lewis Lars Lind Cecilia Lindgren Yongmei Liu Tian Liu Youfang Liu Östen Ljunggren Mattias Lorentzon Robert N Luben William Maixner Fiona E McGuigan Carolina Medina-Gomez Thomas Meitinger Håkan Melhus Dan Mellström Simon Melov Karl Michaëlsson Braxton D Mitchell Andrew P Morris Leif Mosekilde Anne Newman Carrie M Nielson Jeffrey R O'Connell Ben A Oostra Eric S Orwoll Aarno Palotie Stephen C J Parker Munro Peacock Markus Perola Annette Peters Ozren Polasek Richard L Prince Katri Räikkönen Stuart H Ralston Samuli Ripatti John A Robbins Jerome I Rotter Igor Rudan Veikko Salomaa Suzanne Satterfield Eric E Schadt Sabine Schipf Laura Scott Joban Sehmi Jian Shen Chan Soo Shin Gunnar Sigurdsson Shad Smith Nicole Soranzo Alena Stančáková Elisabeth Steinhagen-Thiessen Elizabeth A Streeten Unnur Styrkarsdottir Karin M A Swart Sian-Tsung Tan Mark A Tarnopolsky Patricia Thompson Cynthia A Thomson Unnur Thorsteinsdottir Emmi Tikkanen Gregory J Tranah Jaakko Tuomilehto Natasja M van Schoor Arjun Verma Peter Vollenweider Henry Völzke Jean Wactawski-Wende Mark Walker Michael N Weedon Ryan Welch H-Erich Wichmann Elisabeth Widen Frances M K Williams James F Wilson Nicole C Wright Weijia Xie Lei Yu Yanhua Zhou John C Chambers Angela Döring Cornelia M van Duijn Michael J Econs Vilmundur Gudnason Jaspal S Kooner Bruce M Psaty Timothy D Spector Kari Stefansson Fernando Rivadeneira André G Uitterlinden Nicholas J Wareham Vicky Ossowski Dawn Waterworth Ruth J F Loos David Karasik Tamara B Harris Claes Ohlsson Douglas P Kiel

Nat Commun 2017 11 7;8(1):1414. Epub 2017 Nov 7.

Hebrew SeniorLife, Institute for Aging Research, Roslindale, MA, 02131, USA.

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http://dx.doi.org/10.1038/s41467-017-01008-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5676783PMC
November 2017

Low Serum DHEAS Predicts Increased Fracture Risk in Older Men: The MrOS Sweden Study.

J Bone Miner Res 2017 Aug 30;32(8):1607-1614. Epub 2017 Mar 30.

Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

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http://dx.doi.org/10.1002/jbmr.3123DOI Listing
August 2017

Low-Frequency Synonymous Coding Variation in CYP2R1 Has Large Effects on Vitamin D Levels and Risk of Multiple Sclerosis.

Am J Hum Genet 2017 Aug 27;101(2):227-238. Epub 2017 Jul 27.

Department of Human Genetics, McGill University, Montreal, QC H3A 1B1, Canada; Lady Davis Institute for Medical Research, Jewish General Hospital, McGill University, Montreal, QC H3T 1E2, Canada; Department of Twin Research and Genetic Epidemiology, King's College London, London WC2R 2LS, UK; Department of Medicine, McGill University, Montreal, QC H3G 1Y6, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2017.06.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5544392PMC
August 2017

Correction: Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.

Authors:
Mariaelisa Graff Robert A Scott Anne E Justice Kristin L Young Mary F Feitosa Llilda Barata Thomas W Winkler Audrey Y Chu Anubha Mahajan David Hadley Luting Xue Tsegaselassie Workalemahu Nancy L Heard-Costa Marcel den Hoed Tarunveer S Ahluwalia Qibin Qi Julius S Ngwa Frida Renström Lydia Quaye John D Eicher James E Hayes Marilyn Cornelis Zoltan Kutalik Elise Lim Jian'an Luan Jennifer E Huffman Weihua Zhang Wei Zhao Paula J Griffin Toomas Haller Shafqat Ahmad Pedro M Marques-Vidal Stephanie Bien Loic Yengo Alexander Teumer Albert Vernon Smith Meena Kumari Marie Neergaard Harder Johanne Marie Justesen Marcus E Kleber Mette Hollensted Kurt Lohman Natalia V Rivera John B Whitfield Jing Hua Zhao Heather M Stringham Leo-Pekka Lyytikäinen Charlotte Huppertz Gonneke Willemsen Wouter J Peyrot Ying Wu Kati Kristiansson Ayse Demirkan Myriam Fornage Maija Hassinen Lawrence F Bielak Gemma Cadby Toshiko Tanaka Reedik Mägi Peter J van der Most Anne U Jackson Jennifer L Bragg-Gresham Veronique Vitart Jonathan Marten Pau Navarro Claire Bellis Dorota Pasko Åsa Johansson Søren Snitker Yu-Ching Cheng Joel Eriksson Unhee Lim Mette Aadahl Linda S Adair Najaf Amin Beverley Balkau Juha Auvinen John Beilby Richard N Bergman Sven Bergmann Alain G Bertoni John Blangero Amélie Bonnefond Lori L Bonnycastle Judith B Borja Søren Brage Fabio Busonero Steve Buyske Harry Campbell Peter S Chines Francis S Collins Tanguy Corre George Davey Smith Graciela E Delgado Nicole Dueker Marcus Dörr Tapani Ebeling Gudny Eiriksdottir Tõnu Esko Jessica D Faul Mao Fu Kristine Færch Christian Gieger Sven Gläser Jian Gong Penny Gordon-Larsen Harald Grallert Tanja B Grammer Niels Grarup Gerard van Grootheest Kennet Harald Nicholas D Hastie Aki S Havulinna Dena Hernandez Lucia Hindorff Lynne J Hocking Oddgeir L Holmens Christina Holzapfel Jouke Jan Hottenga Jie Huang Tao Huang Jennie Hui Cornelia Huth Nina Hutri-Kähönen Alan L James John-Olov Jansson Min A Jhun Markus Juonala Leena Kinnunen Heikki A Koistinen Ivana Kolcic Pirjo Komulainen Johanna Kuusisto Kirsti Kvaløy Mika Kähönen Timo A Lakka Lenore J Launer Benjamin Lehne Cecilia M Lindgren Mattias Lorentzon Robert Luben Michel Marre Yuri Milaneschi Keri L Monda Grant W Montgomery Marleen H M De Moor Antonella Mulas Martina Müller-Nurasyid A W Musk Reija Männikkö Satu Männistö Narisu Narisu Matthias Nauck Jennifer A Nettleton Ilja M Nolte Albertine J Oldehinkel Matthias Olden Ken K Ong Sandosh Padmanabhan Lavinia Paternoster Jeremiah Perez Markus Perola Annette Peters Ulrike Peters Patricia A Peyser Inga Prokopenko Hannu Puolijoki Olli T Raitakari Tuomo Rankinen Laura J Rasmussen-Torvik Rajesh Rawal Paul M Ridker Lynda M Rose Igor Rudan Cinzia Sarti Mark A Sarzynski Kai Savonen William R Scott Serena Sanna Alan R Shuldiner Steve Sidney Günther Silbernagel Blair H Smith Jennifer A Smith Harold Snieder Alena Stančáková Barbara Sternfeld Amy J Swift Tuija Tammelin Sian-Tsung Tan Barbara Thorand Dorothée Thuillier Liesbeth Vandenput Henrik Vestergaard Jana V van Vliet-Ostaptchouk Marie-Claude Vohl Uwe Völker Gérard Waeber Mark Walker Sarah Wild Andrew Wong Alan F Wright M Carola Zillikens Niha Zubair Christopher A Haiman Loic Lemarchand Ulf Gyllensten Claes Ohlsson Albert Hofman Fernando Rivadeneira André G Uitterlinden Louis Pérusse James F Wilson Caroline Hayward Ozren Polasek Francesco Cucca Kristian Hveem Catharina A Hartman Anke Tönjes Stefania Bandinelli Lyle J Palmer Sharon L R Kardia Rainer Rauramaa Thorkild I A Sørensen Jaakko Tuomilehto Veikko Salomaa Brenda W J H Penninx Eco J C de Geus Dorret I Boomsma Terho Lehtimäki Massimo Mangino Markku Laakso Claude Bouchard Nicholas G Martin Diana Kuh Yongmei Liu Allan Linneberg Winfried März Konstantin Strauch Mika Kivimäki Tamara B Harris Vilmundur Gudnason Henry Völzke Lu Qi Marjo-Riitta Järvelin John C Chambers Jaspal S Kooner Philippe Froguel Charles Kooperberg Peter Vollenweider Göran Hallmans Torben Hansen Oluf Pedersen Andres Metspalu Nicholas J Wareham Claudia Langenberg David R Weir David J Porteous Eric Boerwinkle Daniel I Chasman Gonçalo R Abecasis Inês Barroso Mark I McCarthy Timothy M Frayling Jeffrey R O'Connell Cornelia M van Duijn Michael Boehnke Iris M Heid Karen L Mohlke David P Strachan Caroline S Fox Ching-Ti Liu Joel N Hirschhorn Robert J Klein Andrew D Johnson Ingrid B Borecki Paul W Franks Kari E North L Adrienne Cupples Ruth J F Loos Tuomas O Kilpeläinen

PLoS Genet 2017 Aug 23;13(8):e1006972. Epub 2017 Aug 23.

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http://dx.doi.org/10.1371/journal.pgen.1006972DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5567921PMC
August 2017

Umbilical cord blood androgen levels in girls and boys assessed by gas chromatography-tandem mass spectrometry.

J Steroid Biochem Mol Biol 2017 07 31;171:195-200. Epub 2017 Mar 31.

Wallenberg Laboratory for Cardiovascular and Metabolic Research, Sahlgrenska University Hospital, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, University of Gothenburg, Bruna Stråket 16, SE-413 45 Gothenburg, Sweden. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09600760173009
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http://dx.doi.org/10.1016/j.jsbmb.2017.03.022DOI Listing
July 2017

Large meta-analysis of genome-wide association studies identifies five loci for lean body mass.

Authors:
M Carola Zillikens Serkalem Demissie Yi-Hsiang Hsu Laura M Yerges-Armstrong Wen-Chi Chou Lisette Stolk Gregory Livshits Linda Broer Toby Johnson Daniel L Koller Zoltán Kutalik Jian'an Luan Ida Malkin Janina S Ried Albert V Smith Gudmar Thorleifsson Liesbeth Vandenput Jing Hua Zhao Weihua Zhang Ali Aghdassi Kristina Åkesson Najaf Amin Leslie J Baier Inês Barroso David A Bennett Lars Bertram Rainer Biffar Murielle Bochud Michael Boehnke Ingrid B Borecki Aron S Buchman Liisa Byberg Harry Campbell Natalia Campos Obanda Jane A Cauley Peggy M Cawthon Henna Cederberg Zhao Chen Nam H Cho Hyung Jin Choi Melina Claussnitzer Francis Collins Steven R Cummings Philip L De Jager Ilja Demuth Rosalie A M Dhonukshe-Rutten Luda Diatchenko Gudny Eiriksdottir Anke W Enneman Mike Erdos Johan G Eriksson Joel Eriksson Karol Estrada Daniel S Evans Mary F Feitosa Mao Fu Melissa Garcia Christian Gieger Thomas Girke Nicole L Glazer Harald Grallert Jagvir Grewal Bok-Ghee Han Robert L Hanson Caroline Hayward Albert Hofman Eric P Hoffman Georg Homuth Wen-Chi Hsueh Monica J Hubal Alan Hubbard Kim M Huffman Lise B Husted Thomas Illig Erik Ingelsson Till Ittermann John-Olov Jansson Joanne M Jordan Antti Jula Magnus Karlsson Kay-Tee Khaw Tuomas O Kilpeläinen Norman Klopp Jacqueline S L Kloth Heikki A Koistinen William E Kraus Stephen Kritchevsky Teemu Kuulasmaa Johanna Kuusisto Markku Laakso Jari Lahti Thomas Lang Bente L Langdahl Lenore J Launer Jong-Young Lee Markus M Lerch Joshua R Lewis Lars Lind Cecilia Lindgren Yongmei Liu Tian Liu Youfang Liu Östen Ljunggren Mattias Lorentzon Robert N Luben William Maixner Fiona E McGuigan Carolina Medina-Gomez Thomas Meitinger Håkan Melhus Dan Mellström Simon Melov Karl Michaëlsson Braxton D Mitchell Andrew P Morris Leif Mosekilde Anne Newman Carrie M Nielson Jeffrey R O'Connell Ben A Oostra Eric S Orwoll Aarno Palotie Stephen C J Parker Munro Peacock Markus Perola Annette Peters Ozren Polasek Richard L Prince Katri Räikkönen Stuart H Ralston Samuli Ripatti John A Robbins Jerome I Rotter Igor Rudan Veikko Salomaa Suzanne Satterfield Eric E Schadt Sabine Schipf Laura Scott Joban Sehmi Jian Shen Chan Soo Shin Gunnar Sigurdsson Shad Smith Nicole Soranzo Alena Stančáková Elisabeth Steinhagen-Thiessen Elizabeth A Streeten Unnur Styrkarsdottir Karin M A Swart Sian-Tsung Tan Mark A Tarnopolsky Patricia Thompson Cynthia A Thomson Unnur Thorsteinsdottir Emmi Tikkanen Gregory J Tranah Jaakko Tuomilehto Natasja M van Schoor Arjun Verma Peter Vollenweider Henry Völzke Jean Wactawski-Wende Mark Walker Michael N Weedon Ryan Welch H-Erich Wichmann Elisabeth Widen Frances M K Williams James F Wilson Nicole C Wright Weijia Xie Lei Yu Yanhua Zhou John C Chambers Angela Döring Cornelia M van Duijn Michael J Econs Vilmundur Gudnason Jaspal S Kooner Bruce M Psaty Timothy D Spector Kari Stefansson Fernando Rivadeneira André G Uitterlinden Nicholas J Wareham Vicky Ossowski Dawn Waterworth Ruth J F Loos David Karasik Tamara B Harris Claes Ohlsson Douglas P Kiel

Nat Commun 2017 07 19;8(1):80. Epub 2017 Jul 19.

Hebrew SeniorLife, Institute for Aging Research, Roslindale, MA, 02131, USA.

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http://dx.doi.org/10.1038/s41467-017-00031-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5517526PMC
July 2017

Low Testosterone, but Not Estradiol, Is Associated With Incident Falls in Older Men: The International MrOS Study.

J Bone Miner Res 2017 Jun 27;32(6):1174-1181. Epub 2017 Feb 27.

Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

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http://dx.doi.org/10.1002/jbmr.3088DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5466469PMC
June 2017

Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.

Authors:
Anne E Justice Thomas W Winkler Mary F Feitosa Misa Graff Virginia A Fisher Kristin Young Llilda Barata Xuan Deng Jacek Czajkowski David Hadley Julius S Ngwa Tarunveer S Ahluwalia Audrey Y Chu Nancy L Heard-Costa Elise Lim Jeremiah Perez John D Eicher Zoltán Kutalik Luting Xue Anubha Mahajan Frida Renström Joseph Wu Qibin Qi Shafqat Ahmad Tamuno Alfred Najaf Amin Lawrence F Bielak Amelie Bonnefond Jennifer Bragg Gemma Cadby Martina Chittani Scott Coggeshall Tanguy Corre Nese Direk Joel Eriksson Krista Fischer Mathias Gorski Marie Neergaard Harder Momoko Horikoshi Tao Huang Jennifer E Huffman Anne U Jackson Johanne Marie Justesen Stavroula Kanoni Leena Kinnunen Marcus E Kleber Pirjo Komulainen Meena Kumari Unhee Lim Jian'an Luan Leo-Pekka Lyytikäinen Massimo Mangino Ani Manichaikul Jonathan Marten Rita P S Middelberg Martina Müller-Nurasyid Pau Navarro Louis Pérusse Natalia Pervjakova Cinzia Sarti Albert Vernon Smith Jennifer A Smith Alena Stančáková Rona J Strawbridge Heather M Stringham Yun Ju Sung Toshiko Tanaka Alexander Teumer Stella Trompet Sander W van der Laan Peter J van der Most Jana V Van Vliet-Ostaptchouk Sailaja L Vedantam Niek Verweij Jacqueline M Vink Veronique Vitart Ying Wu Loic Yengo Weihua Zhang Jing Hua Zhao Martina E Zimmermann Niha Zubair Gonçalo R Abecasis Linda S Adair Saima Afaq Uzma Afzal Stephan J L Bakker Traci M Bartz John Beilby Richard N Bergman Sven Bergmann Reiner Biffar John Blangero Eric Boerwinkle Lori L Bonnycastle Erwin Bottinger Daniele Braga Brendan M Buckley Steve Buyske Harry Campbell John C Chambers Francis S Collins Joanne E Curran Gert J de Borst Anton J M de Craen Eco J C de Geus George Dedoussis Graciela E Delgado Hester M den Ruijter Gudny Eiriksdottir Anna L Eriksson Tõnu Esko Jessica D Faul Ian Ford Terrence Forrester Karl Gertow Bruna Gigante Nicola Glorioso Jian Gong Harald Grallert Tanja B Grammer Niels Grarup Saskia Haitjema Göran Hallmans Anders Hamsten Torben Hansen Tamara B Harris Catharina A Hartman Maija Hassinen Nicholas D Hastie Andrew C Heath Dena Hernandez Lucia Hindorff Lynne J Hocking Mette Hollensted Oddgeir L Holmen Georg Homuth Jouke Jan Hottenga Jie Huang Joseph Hung Nina Hutri-Kähönen Erik Ingelsson Alan L James John-Olov Jansson Marjo-Riitta Jarvelin Min A Jhun Marit E Jørgensen Markus Juonala Mika Kähönen Magnus Karlsson Heikki A Koistinen Ivana Kolcic Genovefa Kolovou Charles Kooperberg Bernhard K Krämer Johanna Kuusisto Kirsti Kvaløy Timo A Lakka Claudia Langenberg Lenore J Launer Karin Leander Nanette R Lee Lars Lind Cecilia M Lindgren Allan Linneberg Stephane Lobbens Marie Loh Mattias Lorentzon Robert Luben Gitta Lubke Anja Ludolph-Donislawski Sara Lupoli Pamela A F Madden Reija Männikkö Pedro Marques-Vidal Nicholas G Martin Colin A McKenzie Barbara McKnight Dan Mellström Cristina Menni Grant W Montgomery Aw Bill Musk Narisu Narisu Matthias Nauck Ilja M Nolte Albertine J Oldehinkel Matthias Olden Ken K Ong Sandosh Padmanabhan Patricia A Peyser Charlotta Pisinger David J Porteous Olli T Raitakari Tuomo Rankinen D C Rao Laura J Rasmussen-Torvik Rajesh Rawal Treva Rice Paul M Ridker Lynda M Rose Stephanie A Bien Igor Rudan Serena Sanna Mark A Sarzynski Naveed Sattar Kai Savonen David Schlessinger Salome Scholtens Claudia Schurmann Robert A Scott Bengt Sennblad Marten A Siemelink Günther Silbernagel P Eline Slagboom Harold Snieder Jan A Staessen David J Stott Morris A Swertz Amy J Swift Kent D Taylor Bamidele O Tayo Barbara Thorand Dorothee Thuillier Jaakko Tuomilehto Andre G Uitterlinden Liesbeth Vandenput Marie-Claude Vohl Henry Völzke Judith M Vonk Gérard Waeber Melanie Waldenberger R G J Westendorp Sarah Wild Gonneke Willemsen Bruce H R Wolffenbuttel Andrew Wong Alan F Wright Wei Zhao M Carola Zillikens Damiano Baldassarre Beverley Balkau Stefania Bandinelli Carsten A Böger Dorret I Boomsma Claude Bouchard Marcel Bruinenberg Daniel I Chasman Yii-DerIda Chen Peter S Chines Richard S Cooper Francesco Cucca Daniele Cusi Ulf de Faire Luigi Ferrucci Paul W Franks Philippe Froguel Penny Gordon-Larsen Hans-Jörgen Grabe Vilmundur Gudnason Christopher A Haiman Caroline Hayward Kristian Hveem Andrew D Johnson J Wouter Jukema Sharon L R Kardia Mika Kivimaki Jaspal S Kooner Diana Kuh Markku Laakso Terho Lehtimäki Loic Le Marchand Winfried März Mark I McCarthy Andres Metspalu Andrew P Morris Claes Ohlsson Lyle J Palmer Gerard Pasterkamp Oluf Pedersen Annette Peters Ulrike Peters Ozren Polasek Bruce M Psaty Lu Qi Rainer Rauramaa Blair H Smith Thorkild I A Sørensen Konstantin Strauch Henning Tiemeier Elena Tremoli Pim van der Harst Henrik Vestergaard Peter Vollenweider Nicholas J Wareham David R Weir John B Whitfield James F Wilson Jessica Tyrrell Timothy M Frayling Inês Barroso Michael Boehnke Panagiotis Deloukas Caroline S Fox Joel N Hirschhorn David J Hunter Tim D Spector David P Strachan Cornelia M van Duijn Iris M Heid Karen L Mohlke Jonathan Marchini Ruth J F Loos Tuomas O Kilpeläinen Ching-Ti Liu Ingrid B Borecki Kari E North L Adrienne Cupples

Nat Commun 2017 04 26;8:14977. Epub 2017 Apr 26.

Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts 02118, USA.

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April 2017

Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.

Authors:
Mariaelisa Graff Robert A Scott Anne E Justice Kristin L Young Mary F Feitosa Llilda Barata Thomas W Winkler Audrey Y Chu Anubha Mahajan David Hadley Luting Xue Tsegaselassie Workalemahu Nancy L Heard-Costa Marcel den Hoed Tarunveer S Ahluwalia Qibin Qi Julius S Ngwa Frida Renström Lydia Quaye John D Eicher James E Hayes Marilyn Cornelis Zoltan Kutalik Elise Lim Jian'an Luan Jennifer E Huffman Weihua Zhang Wei Zhao Paula J Griffin Toomas Haller Shafqat Ahmad Pedro M Marques-Vidal Stephanie Bien Loic Yengo Alexander Teumer Albert Vernon Smith Meena Kumari Marie Neergaard Harder Johanne Marie Justesen Marcus E Kleber Mette Hollensted Kurt Lohman Natalia V Rivera John B Whitfield Jing Hua Zhao Heather M Stringham Leo-Pekka Lyytikäinen Charlotte Huppertz Gonneke Willemsen Wouter J Peyrot Ying Wu Kati Kristiansson Ayse Demirkan Myriam Fornage Maija Hassinen Lawrence F Bielak Gemma Cadby Toshiko Tanaka Reedik Mägi Peter J van der Most Anne U Jackson Jennifer L Bragg-Gresham Veronique Vitart Jonathan Marten Pau Navarro Claire Bellis Dorota Pasko Åsa Johansson Søren Snitker Yu-Ching Cheng Joel Eriksson Unhee Lim Mette Aadahl Linda S Adair Najaf Amin Beverley Balkau Juha Auvinen John Beilby Richard N Bergman Sven Bergmann Alain G Bertoni John Blangero Amélie Bonnefond Lori L Bonnycastle Judith B Borja Søren Brage Fabio Busonero Steve Buyske Harry Campbell Peter S Chines Francis S Collins Tanguy Corre George Davey Smith Graciela E Delgado Nicole Dueker Marcus Dörr Tapani Ebeling Gudny Eiriksdottir Tõnu Esko Jessica D Faul Mao Fu Kristine Færch Christian Gieger Sven Gläser Jian Gong Penny Gordon-Larsen Harald Grallert Tanja B Grammer Niels Grarup Gerard van Grootheest Kennet Harald Nicholas D Hastie Aki S Havulinna Dena Hernandez Lucia Hindorff Lynne J Hocking Oddgeir L Holmens Christina Holzapfel Jouke Jan Hottenga Jie Huang Tao Huang Jennie Hui Cornelia Huth Nina Hutri-Kähönen Alan L James John-Olov Jansson Min A Jhun Markus Juonala Leena Kinnunen Heikki A Koistinen Ivana Kolcic Pirjo Komulainen Johanna Kuusisto Kirsti Kvaløy Mika Kähönen Timo A Lakka Lenore J Launer Benjamin Lehne Cecilia M Lindgren Mattias Lorentzon Robert Luben Michel Marre Yuri Milaneschi Keri L Monda Grant W Montgomery Marleen H M De Moor Antonella Mulas Martina Müller-Nurasyid A W Musk Reija Männikkö Satu Männistö Narisu Narisu Matthias Nauck Jennifer A Nettleton Ilja M Nolte Albertine J Oldehinkel Matthias Olden Ken K Ong Sandosh Padmanabhan Lavinia Paternoster Jeremiah Perez Markus Perola Annette Peters Ulrike Peters Patricia A Peyser Inga Prokopenko Hannu Puolijoki Olli T Raitakari Tuomo Rankinen Laura J Rasmussen-Torvik Rajesh Rawal Paul M Ridker Lynda M Rose Igor Rudan Cinzia Sarti Mark A Sarzynski Kai Savonen William R Scott Serena Sanna Alan R Shuldiner Steve Sidney Günther Silbernagel Blair H Smith Jennifer A Smith Harold Snieder Alena Stančáková Barbara Sternfeld Amy J Swift Tuija Tammelin Sian-Tsung Tan Barbara Thorand Dorothée Thuillier Liesbeth Vandenput Henrik Vestergaard Jana V van Vliet-Ostaptchouk Marie-Claude Vohl Uwe Völker Gérard Waeber Mark Walker Sarah Wild Andrew Wong Alan F Wright M Carola Zillikens Niha Zubair Christopher A Haiman Loic Lemarchand Ulf Gyllensten Claes Ohlsson Albert Hofman Fernando Rivadeneira André G Uitterlinden Louis Pérusse James F Wilson Caroline Hayward Ozren Polasek Francesco Cucca Kristian Hveem Catharina A Hartman Anke Tönjes Stefania Bandinelli Lyle J Palmer Sharon L R Kardia Rainer Rauramaa Thorkild I A Sørensen Jaakko Tuomilehto Veikko Salomaa Brenda W J H Penninx Eco J C de Geus Dorret I Boomsma Terho Lehtimäki Massimo Mangino Markku Laakso Claude Bouchard Nicholas G Martin Diana Kuh Yongmei Liu Allan Linneberg Winfried März Konstantin Strauch Mika Kivimäki Tamara B Harris Vilmundur Gudnason Henry Völzke Lu Qi Marjo-Riitta Järvelin John C Chambers Jaspal S Kooner Philippe Froguel Charles Kooperberg Peter Vollenweider Göran Hallmans Torben Hansen Oluf Pedersen Andres Metspalu Nicholas J Wareham Claudia Langenberg David R Weir David J Porteous Eric Boerwinkle Daniel I Chasman Gonçalo R Abecasis Inês Barroso Mark I McCarthy Timothy M Frayling Jeffrey R O'Connell Cornelia M van Duijn Michael Boehnke Iris M Heid Karen L Mohlke David P Strachan Caroline S Fox Ching-Ti Liu Joel N Hirschhorn Robert J Klein Andrew D Johnson Ingrid B Borecki Paul W Franks Kari E North L Adrienne Cupples Ruth J F Loos Tuomas O Kilpeläinen

PLoS Genet 2017 Apr 27;13(4):e1006528. Epub 2017 Apr 27.

MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, United Kingdom.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5407576PMC
April 2017

A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape.

Authors:
Janina S Ried Janina Jeff M Audrey Y Chu Jennifer L Bragg-Gresham Jenny van Dongen Jennifer E Huffman Tarunveer S Ahluwalia Gemma Cadby Niina Eklund Joel Eriksson Tõnu Esko Mary F Feitosa Anuj Goel Mathias Gorski Caroline Hayward Nancy L Heard-Costa Anne U Jackson Eero Jokinen Stavroula Kanoni Kati Kristiansson Zoltán Kutalik Jari Lahti Jian'an Luan Reedik Mägi Anubha Mahajan Massimo Mangino Carolina Medina-Gomez Keri L Monda Ilja M Nolte Louis Pérusse Inga Prokopenko Lu Qi Lynda M Rose Erika Salvi Megan T Smith Harold Snieder Alena Stančáková Yun Ju Sung Ioanna Tachmazidou Alexander Teumer Gudmar Thorleifsson Pim van der Harst Ryan W Walker Sophie R Wang Sarah H Wild Sara M Willems Andrew Wong Weihua Zhang Eva Albrecht Alexessander Couto Alves Stephan J L Bakker Cristina Barlassina Traci M Bartz John Beilby Claire Bellis Richard N Bergman Sven Bergmann John Blangero Matthias Blüher Eric Boerwinkle Lori L Bonnycastle Stefan R Bornstein Marcel Bruinenberg Harry Campbell Yii-Der Ida Chen Charleston W K Chiang Peter S Chines Francis S Collins Fracensco Cucca L Adrienne Cupples Francesca D'Avila Eco J C de Geus George Dedoussis Maria Dimitriou Angela Döring Johan G Eriksson Aliki-Eleni Farmaki Martin Farrall Teresa Ferreira Krista Fischer Nita G Forouhi Nele Friedrich Anette Prior Gjesing Nicola Glorioso Mariaelisa Graff Harald Grallert Niels Grarup Jürgen Gräßler Jagvir Grewal Anders Hamsten Marie Neergaard Harder Catharina A Hartman Maija Hassinen Nicholas Hastie Andrew Tym Hattersley Aki S Havulinna Markku Heliövaara Hans Hillege Albert Hofman Oddgeir Holmen Georg Homuth Jouke-Jan Hottenga Jennie Hui Lise Lotte Husemoen Pirro G Hysi Aaron Isaacs Till Ittermann Shapour Jalilzadeh Alan L James Torben Jørgensen Pekka Jousilahti Antti Jula Johanne Marie Justesen Anne E Justice Mika Kähönen Maria Karaleftheri Kay Tee Khaw Sirkka M Keinanen-Kiukaanniemi Leena Kinnunen Paul B Knekt Heikki A Koistinen Ivana Kolcic Ishminder K Kooner Seppo Koskinen Peter Kovacs Theodosios Kyriakou Tomi Laitinen Claudia Langenberg Alexandra M Lewin Peter Lichtner Cecilia M Lindgren Jaana Lindström Allan Linneberg Roberto Lorbeer Mattias Lorentzon Robert Luben Valeriya Lyssenko Satu Männistö Paolo Manunta Irene Mateo Leach Wendy L McArdle Barbara Mcknight Karen L Mohlke Evelin Mihailov Lili Milani Rebecca Mills May E Montasser Andrew P Morris Gabriele Müller Arthur W Musk Narisu Narisu Ken K Ong Ben A Oostra Clive Osmond Aarno Palotie James S Pankow Lavinia Paternoster Brenda W Penninx Irene Pichler Maria G Pilia Ozren Polašek Peter P Pramstaller Olli T Raitakari Tuomo Rankinen D C Rao Nigel W Rayner Rasmus Ribel-Madsen Treva K Rice Marcus Richards Paul M Ridker Fernando Rivadeneira Kathy A Ryan Serena Sanna Mark A Sarzynski Salome Scholtens Robert A Scott Sylvain Sebert Lorraine Southam Thomas Hempel Sparsø Valgerdur Steinthorsdottir Kathleen Stirrups Ronald P Stolk Konstantin Strauch Heather M Stringham Morris A Swertz Amy J Swift Anke Tönjes Emmanouil Tsafantakis Peter J van der Most Jana V Van Vliet-Ostaptchouk Liesbeth Vandenput Erkki Vartiainen Cristina Venturini Niek Verweij Jorma S Viikari Veronique Vitart Marie-Claude Vohl Judith M Vonk Gérard Waeber Elisabeth Widén Gonneke Willemsen Tom Wilsgaard Thomas W Winkler Alan F Wright Laura M Yerges-Armstrong Jing Hua Zhao M Carola Zillikens Dorret I Boomsma Claude Bouchard John C Chambers Daniel I Chasman Daniele Cusi Ron T Gansevoort Christian Gieger Torben Hansen Andrew A Hicks Frank Hu Kristian Hveem Marjo-Riitta Jarvelin Eero Kajantie Jaspal S Kooner Diana Kuh Johanna Kuusisto Markku Laakso Timo A Lakka Terho Lehtimäki Andres Metspalu Inger Njølstad Claes Ohlsson Albertine J Oldehinkel Lyle J Palmer Oluf Pedersen Markus Perola Annette Peters Bruce M Psaty Hannu Puolijoki Rainer Rauramaa Igor Rudan Veikko Salomaa Peter E H Schwarz Alan R Shudiner Jan H Smit Thorkild I A Sørensen Timothy D Spector Kari Stefansson Michael Stumvoll Angelo Tremblay Jaakko Tuomilehto André G Uitterlinden Matti Uusitupa Uwe Völker Peter Vollenweider Nicholas J Wareham Hugh Watkins James F Wilson Eleftheria Zeggini Goncalo R Abecasis Michael Boehnke Ingrid B Borecki Panos Deloukas Cornelia M van Duijn Caroline Fox Leif C Groop Iris M Heid David J Hunter Robert C Kaplan Mark I McCarthy Kari E North Jeffrey R O'Connell David Schlessinger Unnur Thorsteinsdottir David P Strachan Timothy Frayling Joel N Hirschhorn Martina Müller-Nurasyid Ruth J F Loos

Nat Commun 2016 11 23;7:13357. Epub 2016 Nov 23.

The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.

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November 2016

Genomewide meta-analysis identifies loci associated with IGF-I and IGFBP-3 levels with impact on age-related traits.

Aging Cell 2016 Oct 21;15(5):811-24. Epub 2016 Jun 21.

Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY, 10461, USA.

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October 2016

Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.

Authors:
Thomas W Winkler Anne E Justice Mariaelisa Graff Llilda Barata Mary F Feitosa Su Chu Jacek Czajkowski Tõnu Esko Tove Fall Tuomas O Kilpeläinen Yingchang Lu Reedik Mägi Evelin Mihailov Tune H Pers Sina Rüeger Alexander Teumer Georg B Ehret Teresa Ferreira Nancy L Heard-Costa Juha Karjalainen Vasiliki Lagou Anubha Mahajan Michael D Neinast Inga Prokopenko Jeannette Simino Tanya M Teslovich Rick Jansen Harm-Jan Westra Charles C White Devin Absher Tarunveer S Ahluwalia Shafqat Ahmad Eva Albrecht Alexessander Couto Alves Jennifer L Bragg-Gresham Anton J M de Craen Joshua C Bis Amélie Bonnefond Gabrielle Boucher Gemma Cadby Yu-Ching Cheng Charleston W K Chiang Graciela Delgado Ayse Demirkan Nicole Dueker Niina Eklund Gudny Eiriksdottir Joel Eriksson Bjarke Feenstra Krista Fischer Francesca Frau Tessel E Galesloot Frank Geller Anuj Goel Mathias Gorski Tanja B Grammer Stefan Gustafsson Saskia Haitjema Jouke-Jan Hottenga Jennifer E Huffman Anne U Jackson Kevin B Jacobs Åsa Johansson Marika Kaakinen Marcus E Kleber Jari Lahti Irene Mateo Leach Benjamin Lehne Youfang Liu Ken Sin Lo Mattias Lorentzon Jian'an Luan Pamela A F Madden Massimo Mangino Barbara McKnight Carolina Medina-Gomez Keri L Monda May E Montasser Gabriele Müller Martina Müller-Nurasyid Ilja M Nolte Kalliope Panoutsopoulou Laura Pascoe Lavinia Paternoster Nigel W Rayner Frida Renström Federica Rizzi Lynda M Rose Kathy A Ryan Perttu Salo Serena Sanna Hubert Scharnagl Jianxin Shi Albert Vernon Smith Lorraine Southam Alena Stančáková Valgerdur Steinthorsdottir Rona J Strawbridge Yun Ju Sung Ioanna Tachmazidou Toshiko Tanaka Gudmar Thorleifsson Stella Trompet Natalia Pervjakova Jonathan P Tyrer Liesbeth Vandenput Sander W van der Laan Nathalie van der Velde Jessica van Setten Jana V van Vliet-Ostaptchouk Niek Verweij Efthymia Vlachopoulou Lindsay L Waite Sophie R Wang Zhaoming Wang Sarah H Wild Christina Willenborg James F Wilson Andrew Wong Jian Yang Loïc Yengo Laura M Yerges-Armstrong Lei Yu Weihua Zhang Jing Hua Zhao Ehm A Andersson Stephan J L Bakker Damiano Baldassarre Karina Banasik Matteo Barcella Cristina Barlassina Claire Bellis Paola Benaglio John Blangero Matthias Blüher Fabrice Bonnet Lori L Bonnycastle Heather A Boyd Marcel Bruinenberg Aron S Buchman Harry Campbell Yii-Der Ida Chen Peter S Chines Simone Claudi-Boehm John Cole Francis S Collins Eco J C de Geus Lisette C P G M de Groot Maria Dimitriou Jubao Duan Stefan Enroth Elodie Eury Aliki-Eleni Farmaki Nita G Forouhi Nele Friedrich Pablo V Gejman Bruna Gigante Nicola Glorioso Alan S Go Omri Gottesman Jürgen Gräßler Harald Grallert Niels Grarup Yu-Mei Gu Linda Broer Annelies C Ham Torben Hansen Tamara B Harris Catharina A Hartman Maija Hassinen Nicholas Hastie Andrew T Hattersley Andrew C Heath Anjali K Henders Dena Hernandez Hans Hillege Oddgeir Holmen Kees G Hovingh Jennie Hui Lise L Husemoen Nina Hutri-Kähönen Pirro G Hysi Thomas Illig Philip L De Jager Shapour Jalilzadeh Torben Jørgensen J Wouter Jukema Markus Juonala Stavroula Kanoni Maria Karaleftheri Kay Tee Khaw Leena Kinnunen Steven J Kittner Wolfgang Koenig Ivana Kolcic Peter Kovacs Nikolaj T Krarup Wolfgang Kratzer Janine Krüger Diana Kuh Meena Kumari Theodosios Kyriakou Claudia Langenberg Lars Lannfelt Chiara Lanzani Vaneet Lotay Lenore J Launer Karin Leander Jaana Lindström Allan Linneberg Yan-Ping Liu Stéphane Lobbens Robert Luben Valeriya Lyssenko Satu Männistö Patrik K Magnusson Wendy L McArdle Cristina Menni Sigrun Merger Lili Milani Grant W Montgomery Andrew P Morris Narisu Narisu Mari Nelis Ken K Ong Aarno Palotie Louis Pérusse Irene Pichler Maria G Pilia Anneli Pouta Myriam Rheinberger Rasmus Ribel-Madsen Marcus Richards Kenneth M Rice Treva K Rice Carlo Rivolta Veikko Salomaa Alan R Sanders Mark A Sarzynski Salome Scholtens Robert A Scott William R Scott Sylvain Sebert Sebanti Sengupta Bengt Sennblad Thomas Seufferlein Angela Silveira P Eline Slagboom Jan H Smit Thomas H Sparsø Kathleen Stirrups Ronald P Stolk Heather M Stringham Morris A Swertz Amy J Swift Ann-Christine Syvänen Sian-Tsung Tan Barbara Thorand Anke Tönjes Angelo Tremblay Emmanouil Tsafantakis Peter J van der Most Uwe Völker Marie-Claude Vohl Judith M Vonk Melanie Waldenberger Ryan W Walker Roman Wennauer Elisabeth Widén Gonneke Willemsen Tom Wilsgaard Alan F Wright M Carola Zillikens Suzanne C van Dijk Natasja M van Schoor Folkert W Asselbergs Paul I W de Bakker Jacques S Beckmann John Beilby David A Bennett Richard N Bergman Sven Bergmann Carsten A Böger Bernhard O Boehm Eric Boerwinkle Dorret I Boomsma Stefan R Bornstein Erwin P Bottinger Claude Bouchard John C Chambers Stephen J Chanock Daniel I Chasman Francesco Cucca Daniele Cusi George Dedoussis Jeanette Erdmann Johan G Eriksson Denis A Evans Ulf de Faire Martin Farrall Luigi Ferrucci Ian Ford Lude Franke Paul W Franks Philippe Froguel Ron T Gansevoort Christian Gieger Henrik Grönberg Vilmundur Gudnason Ulf Gyllensten Per Hall Anders Hamsten Pim van der Harst Caroline Hayward Markku Heliövaara Christian Hengstenberg Andrew A Hicks Aroon Hingorani Albert Hofman Frank Hu Heikki V Huikuri Kristian Hveem Alan L James Joanne M Jordan Antti Jula Mika Kähönen Eero Kajantie Sekar Kathiresan Lambertus A L M Kiemeney Mika Kivimaki Paul B Knekt Heikki A Koistinen Jaspal S Kooner Seppo Koskinen Johanna Kuusisto Winfried Maerz Nicholas G Martin Markku Laakso Timo A Lakka Terho Lehtimäki Guillaume Lettre Douglas F Levinson Lars Lind Marja-Liisa Lokki Pekka Mäntyselkä Mads Melbye Andres Metspalu Braxton D Mitchell Frans L Moll Jeffrey C Murray Arthur W Musk Markku S Nieminen Inger Njølstad Claes Ohlsson Albertine J Oldehinkel Ben A Oostra Lyle J Palmer James S Pankow Gerard Pasterkamp Nancy L Pedersen Oluf Pedersen Brenda W Penninx Markus Perola Annette Peters Ozren Polašek Peter P Pramstaller Bruce M Psaty Lu Qi Thomas Quertermous Olli T Raitakari Tuomo Rankinen Rainer Rauramaa Paul M Ridker John D Rioux Fernando Rivadeneira Jerome I Rotter Igor Rudan Hester M den Ruijter Juha Saltevo Naveed Sattar Heribert Schunkert Peter E H Schwarz Alan R Shuldiner Juha Sinisalo Harold Snieder Thorkild I A Sørensen Tim D Spector Jan A Staessen Bandinelli Stefania Unnur Thorsteinsdottir Michael Stumvoll Jean-Claude Tardif Elena Tremoli Jaakko Tuomilehto André G Uitterlinden Matti Uusitupa André L M Verbeek Sita H Vermeulen Jorma S Viikari Veronique Vitart Henry Völzke Peter Vollenweider Gérard Waeber Mark Walker Henri Wallaschofski Nicholas J Wareham Hugh Watkins Eleftheria Zeggini Aravinda Chakravarti Deborah J Clegg L Adrienne Cupples Penny Gordon-Larsen Cashell E Jaquish D C Rao Goncalo R Abecasis Themistocles L Assimes Inês Barroso Sonja I Berndt Michael Boehnke Panos Deloukas Caroline S Fox Leif C Groop David J Hunter Erik Ingelsson Robert C Kaplan Mark I McCarthy Karen L Mohlke Jeffrey R O'Connell David Schlessinger David P Strachan Kari Stefansson Cornelia M van Duijn Joel N Hirschhorn Cecilia M Lindgren Iris M Heid Kari E North Ingrid B Borecki Zoltán Kutalik Ruth J F Loos

PLoS Genet 2016 06 29;12(6):e1006166. Epub 2016 Jun 29.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4927064PMC
June 2016

High Serum SHBG Predicts Incident Vertebral Fractures in Elderly Men.

J Bone Miner Res 2016 Mar 20;31(3):683-9. Epub 2016 Jan 20.

Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832265PMC
March 2016

Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels.

Authors:
Tuomas O Kilpeläinen Jayne F Martin Carli Alicja A Skowronski Qi Sun Jennifer Kriebel Mary F Feitosa Åsa K Hedman Alexander W Drong James E Hayes Jinghua Zhao Tune H Pers Ursula Schick Niels Grarup Zoltán Kutalik Stella Trompet Massimo Mangino Kati Kristiansson Marian Beekman Leo-Pekka Lyytikäinen Joel Eriksson Peter Henneman Jari Lahti Toshiko Tanaka Jian'an Luan Fabiola Del Greco M Dorota Pasko Frida Renström Sara M Willems Anubha Mahajan Lynda M Rose Xiuqing Guo Yongmei Liu Marcus E Kleber Louis Pérusse Tom Gaunt Tarunveer S Ahluwalia Yun Ju Sung Yolande F Ramos Najaf Amin Antoinette Amuzu Inês Barroso Claire Bellis John Blangero Brendan M Buckley Stefan Böhringer Yii-Der I Chen Anton J N de Craen David R Crosslin Caroline E Dale Zari Dastani Felix R Day Joris Deelen Graciela E Delgado Ayse Demirkan Francis M Finucane Ian Ford Melissa E Garcia Christian Gieger Stefan Gustafsson Göran Hallmans Susan E Hankinson Aki S Havulinna Christian Herder Dena Hernandez Andrew A Hicks David J Hunter Thomas Illig Erik Ingelsson Andreea Ioan-Facsinay John-Olov Jansson Nancy S Jenny Marit E Jørgensen Torben Jørgensen Magnus Karlsson Wolfgang Koenig Peter Kraft Joanneke Kwekkeboom Tiina Laatikainen Karl-Heinz Ladwig Charles A LeDuc Gordon Lowe Yingchang Lu Pedro Marques-Vidal Christa Meisinger Cristina Menni Andrew P Morris Richard H Myers Satu Männistö Mike A Nalls Lavinia Paternoster Annette Peters Aruna D Pradhan Tuomo Rankinen Laura J Rasmussen-Torvik Wolfgang Rathmann Treva K Rice J Brent Richards Paul M Ridker Naveed Sattar David B Savage Stefan Söderberg Nicholas J Timpson Liesbeth Vandenput Diana van Heemst Hae-Won Uh Marie-Claude Vohl Mark Walker Heinz-Erich Wichmann Elisabeth Widén Andrew R Wood Jie Yao Tanja Zeller Yiying Zhang Ingrid Meulenbelt Margreet Kloppenburg Arne Astrup Thorkild I A Sørensen Mark A Sarzynski D C Rao Pekka Jousilahti Erkki Vartiainen Albert Hofman Fernando Rivadeneira André G Uitterlinden Eero Kajantie Clive Osmond Aarno Palotie Johan G Eriksson Markku Heliövaara Paul B Knekt Seppo Koskinen Antti Jula Markus Perola Risto K Huupponen Jorma S Viikari Mika Kähönen Terho Lehtimäki Olli T Raitakari Dan Mellström Mattias Lorentzon Juan P Casas Stefanie Bandinelli Winfried März Aaron Isaacs Ko W van Dijk Cornelia M van Duijn Tamara B Harris Claude Bouchard Matthew A Allison Daniel I Chasman Claes Ohlsson Lars Lind Robert A Scott Claudia Langenberg Nicholas J Wareham Luigi Ferrucci Timothy M Frayling Peter P Pramstaller Ingrid B Borecki Dawn M Waterworth Sven Bergmann Gérard Waeber Peter Vollenweider Henrik Vestergaard Torben Hansen Oluf Pedersen Frank B Hu P Eline Slagboom Harald Grallert Tim D Spector J W Jukema Robert J Klein Erik E Schadt Paul W Franks Cecilia M Lindgren Rudolph L Leibel Ruth J F Loos

Nat Commun 2016 Feb 1;7:10494. Epub 2016 Feb 1.

MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge CB2 0QQ, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4740377PMC
February 2016

New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk.

Authors:
Yingchang Lu Felix R Day Stefan Gustafsson Martin L Buchkovich Jianbo Na Veronique Bataille Diana L Cousminer Zari Dastani Alexander W Drong Tõnu Esko David M Evans Mario Falchi Mary F Feitosa Teresa Ferreira Åsa K Hedman Robin Haring Pirro G Hysi Mark M Iles Anne E Justice Stavroula Kanoni Vasiliki Lagou Rui Li Xin Li Adam Locke Chen Lu Reedik Mägi John R B Perry Tune H Pers Qibin Qi Marianna Sanna Ellen M Schmidt William R Scott Dmitry Shungin Alexander Teumer Anna A E Vinkhuyzen Ryan W Walker Harm-Jan Westra Mingfeng Zhang Weihua Zhang Jing Hua Zhao Zhihong Zhu Uzma Afzal Tarunveer Singh Ahluwalia Stephan J L Bakker Claire Bellis Amélie Bonnefond Katja Borodulin Aron S Buchman Tommy Cederholm Audrey C Choh Hyung Jin Choi Joanne E Curran Lisette C P G M de Groot Philip L De Jager Rosalie A M Dhonukshe-Rutten Anke W Enneman Elodie Eury Daniel S Evans Tom Forsen Nele Friedrich Frédéric Fumeron Melissa E Garcia Simone Gärtner Bok-Ghee Han Aki S Havulinna Caroline Hayward Dena Hernandez Hans Hillege Till Ittermann Jack W Kent Ivana Kolcic Tiina Laatikainen Jari Lahti Irene Mateo Leach Christine G Lee Jong-Young Lee Tian Liu Youfang Liu Stéphane Lobbens Marie Loh Leo-Pekka Lyytikäinen Carolina Medina-Gomez Karl Michaëlsson Mike A Nalls Carrie M Nielson Laticia Oozageer Laura Pascoe Lavinia Paternoster Ozren Polašek Samuli Ripatti Mark A Sarzynski Chan Soo Shin Nina Smolej Narančić Dominik Spira Priya Srikanth Elisabeth Steinhagen-Thiessen Yun Ju Sung Karin M A Swart Leena Taittonen Toshiko Tanaka Emmi Tikkanen Nathalie van der Velde Natasja M van Schoor Niek Verweij Alan F Wright Lei Yu Joseph M Zmuda Niina Eklund Terrence Forrester Niels Grarup Anne U Jackson Kati Kristiansson Teemu Kuulasmaa Johanna Kuusisto Peter Lichtner Jian'an Luan Anubha Mahajan Satu Männistö Cameron D Palmer Janina S Ried Robert A Scott Alena Stancáková Peter J Wagner Ayse Demirkan Angela Döring Vilmundur Gudnason Douglas P Kiel Brigitte Kühnel Massimo Mangino Barbara Mcknight Cristina Menni Jeffrey R O'Connell Ben A Oostra Alan R Shuldiner Kijoung Song Liesbeth Vandenput Cornelia M van Duijn Peter Vollenweider Charles C White Michael Boehnke Yvonne Boettcher Richard S Cooper Nita G Forouhi Christian Gieger Harald Grallert Aroon Hingorani Torben Jørgensen Pekka Jousilahti Mika Kivimaki Meena Kumari Markku Laakso Claudia Langenberg Allan Linneberg Amy Luke Colin A Mckenzie Aarno Palotie Oluf Pedersen Annette Peters Konstantin Strauch Bamidele O Tayo Nicholas J Wareham David A Bennett Lars Bertram John Blangero Matthias Blüher Claude Bouchard Harry Campbell Nam H Cho Steven R Cummings Stefan A Czerwinski Ilja Demuth Rahel Eckardt Johan G Eriksson Luigi Ferrucci Oscar H Franco Philippe Froguel Ron T Gansevoort Torben Hansen Tamara B Harris Nicholas Hastie Markku Heliövaara Albert Hofman Joanne M Jordan Antti Jula Mika Kähönen Eero Kajantie Paul B Knekt Seppo Koskinen Peter Kovacs Terho Lehtimäki Lars Lind Yongmei Liu Eric S Orwoll Clive Osmond Markus Perola Louis Pérusse Olli T Raitakari Tuomo Rankinen D C Rao Treva K Rice Fernando Rivadeneira Igor Rudan Veikko Salomaa Thorkild I A Sørensen Michael Stumvoll Anke Tönjes Bradford Towne Gregory J Tranah Angelo Tremblay André G Uitterlinden Pim van der Harst Erkki Vartiainen Jorma S Viikari Veronique Vitart Marie-Claude Vohl Henry Völzke Mark Walker Henri Wallaschofski Sarah Wild James F Wilson Loïc Yengo D Timothy Bishop Ingrid B Borecki John C Chambers L Adrienne Cupples Abbas Dehghan Panos Deloukas Ghazaleh Fatemifar Caroline Fox Terrence S Furey Lude Franke Jiali Han David J Hunter Juha Karjalainen Fredrik Karpe Robert C Kaplan Jaspal S Kooner Mark I McCarthy Joanne M Murabito Andrew P Morris Julia A N Bishop Kari E North Claes Ohlsson Ken K Ong Inga Prokopenko J Brent Richards Eric E Schadt Tim D Spector Elisabeth Widén Cristen J Willer Jian Yang Erik Ingelsson Karen L Mohlke Joel N Hirschhorn John Andrew Pospisilik M Carola Zillikens Cecilia Lindgren Tuomas Oskari Kilpeläinen Ruth J F Loos

Nat Commun 2016 Feb 1;7:10495. Epub 2016 Feb 1.

The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4740398PMC
February 2016

Whole-genome sequencing identifies EN1 as a determinant of bone density and fracture.

Authors:
Hou-Feng Zheng Vincenzo Forgetta Yi-Hsiang Hsu Karol Estrada Alberto Rosello-Diez Paul J Leo Chitra L Dahia Kyung Hyun Park-Min Jonathan H Tobias Charles Kooperberg Aaron Kleinman Unnur Styrkarsdottir Ching-Ti Liu Charlotta Uggla Daniel S Evans Carrie M Nielson Klaudia Walter Ulrika Pettersson-Kymmer Shane McCarthy Joel Eriksson Tony Kwan Mila Jhamai Katerina Trajanoska Yasin Memari Josine Min Jie Huang Petr Danecek Beth Wilmot Rui Li Wen-Chi Chou Lauren E Mokry Alireza Moayyeri Melina Claussnitzer Chia-Ho Cheng Warren Cheung Carolina Medina-Gómez Bing Ge Shu-Huang Chen Kwangbom Choi Ling Oei James Fraser Robert Kraaij Matthew A Hibbs Celia L Gregson Denis Paquette Albert Hofman Carl Wibom Gregory J Tranah Mhairi Marshall Brooke B Gardiner Katie Cremin Paul Auer Li Hsu Sue Ring Joyce Y Tung Gudmar Thorleifsson Anke W Enneman Natasja M van Schoor Lisette C P G M de Groot Nathalie van der Velde Beatrice Melin John P Kemp Claus Christiansen Adrian Sayers Yanhua Zhou Sophie Calderari Jeroen van Rooij Chris Carlson Ulrike Peters Soizik Berlivet Josée Dostie Andre G Uitterlinden Stephen R Williams Charles Farber Daniel Grinberg Andrea Z LaCroix Jeff Haessler Daniel I Chasman Franco Giulianini Lynda M Rose Paul M Ridker John A Eisman Tuan V Nguyen Jacqueline R Center Xavier Nogues Natalia Garcia-Giralt Lenore L Launer Vilmunder Gudnason Dan Mellström Liesbeth Vandenput Najaf Amin Cornelia M van Duijn Magnus K Karlsson Östen Ljunggren Olle Svensson Göran Hallmans François Rousseau Sylvie Giroux Johanne Bussière Pascal P Arp Fjorda Koromani Richard L Prince Joshua R Lewis Bente L Langdahl A Pernille Hermann Jens-Erik B Jensen Stephen Kaptoge Kay-Tee Khaw Jonathan Reeve Melissa M Formosa Angela Xuereb-Anastasi Kristina Åkesson Fiona E McGuigan Gaurav Garg Jose M Olmos Maria T Zarrabeitia Jose A Riancho Stuart H Ralston Nerea Alonso Xi Jiang David Goltzman Tomi Pastinen Elin Grundberg Dominique Gauguier Eric S Orwoll David Karasik George Davey-Smith Albert V Smith Kristin Siggeirsdottir Tamara B Harris M Carola Zillikens Joyce B J van Meurs Unnur Thorsteinsdottir Matthew T Maurano Nicholas J Timpson Nicole Soranzo Richard Durbin Scott G Wilson Evangelia E Ntzani Matthew A Brown Kari Stefansson David A Hinds Tim Spector L Adrienne Cupples Claes Ohlsson Celia M T Greenwood Rebecca D Jackson David W Rowe Cynthia A Loomis David M Evans Cheryl L Ackert-Bicknell Alexandra L Joyner Emma L Duncan Douglas P Kiel Fernando Rivadeneira J Brent Richards

Nature 2015 Oct 14;526(7571):112-7. Epub 2015 Sep 14.

Departments of Medicine, Human Genetics, Epidemiology and Biostatistics, McGill University, Montréal H3A 1A2, Canada.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4755714PMC
October 2015

The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.

Authors:
Thomas W Winkler Anne E Justice Mariaelisa Graff Llilda Barata Mary F Feitosa Su Chu Jacek Czajkowski Tõnu Esko Tove Fall Tuomas O Kilpeläinen Yingchang Lu Reedik Mägi Evelin Mihailov Tune H Pers Sina Rüeger Alexander Teumer Georg B Ehret Teresa Ferreira Nancy L Heard-Costa Juha Karjalainen Vasiliki Lagou Anubha Mahajan Michael D Neinast Inga Prokopenko Jeannette Simino Tanya M Teslovich Rick Jansen Harm-Jan Westra Charles C White Devin Absher Tarunveer S Ahluwalia Shafqat Ahmad Eva Albrecht Alexessander Couto Alves Jennifer L Bragg-Gresham Anton J M de Craen Joshua C Bis Amélie Bonnefond Gabrielle Boucher Gemma Cadby Yu-Ching Cheng Charleston W K Chiang Graciela Delgado Ayse Demirkan Nicole Dueker Niina Eklund Gudny Eiriksdottir Joel Eriksson Bjarke Feenstra Krista Fischer Francesca Frau Tessel E Galesloot Frank Geller Anuj Goel Mathias Gorski Tanja B Grammer Stefan Gustafsson Saskia Haitjema Jouke-Jan Hottenga Jennifer E Huffman Anne U Jackson Kevin B Jacobs Åsa Johansson Marika Kaakinen Marcus E Kleber Jari Lahti Irene Mateo Leach Benjamin Lehne Youfang Liu Ken Sin Lo Mattias Lorentzon Jian'an Luan Pamela A F Madden Massimo Mangino Barbara McKnight Carolina Medina-Gomez Keri L Monda May E Montasser Gabriele Müller Martina Müller-Nurasyid Ilja M Nolte Kalliope Panoutsopoulou Laura Pascoe Lavinia Paternoster Nigel W Rayner Frida Renström Federica Rizzi Lynda M Rose Kathy A Ryan Perttu Salo Serena Sanna Hubert Scharnagl Jianxin Shi Albert Vernon Smith Lorraine Southam Alena Stančáková Valgerdur Steinthorsdottir Rona J Strawbridge Yun Ju Sung Ioanna Tachmazidou Toshiko Tanaka Gudmar Thorleifsson Stella Trompet Natalia Pervjakova Jonathan P Tyrer Liesbeth Vandenput Sander W van der Laan Nathalie van der Velde Jessica van Setten Jana V van Vliet-Ostaptchouk Niek Verweij Efthymia Vlachopoulou Lindsay L Waite Sophie R Wang Zhaoming Wang Sarah H Wild Christina Willenborg James F Wilson Andrew Wong Jian Yang Loïc Yengo Laura M Yerges-Armstrong Lei Yu Weihua Zhang Jing Hua Zhao Ehm A Andersson Stephan J L Bakker Damiano Baldassarre Karina Banasik Matteo Barcella Cristina Barlassina Claire Bellis Paola Benaglio John Blangero Matthias Blüher Fabrice Bonnet Lori L Bonnycastle Heather A Boyd Marcel Bruinenberg Aron S Buchman Harry Campbell Yii-Der Ida Chen Peter S Chines Simone Claudi-Boehm John Cole Francis S Collins Eco J C de Geus Lisette C P G M de Groot Maria Dimitriou Jubao Duan Stefan Enroth Elodie Eury Aliki-Eleni Farmaki Nita G Forouhi Nele Friedrich Pablo V Gejman Bruna Gigante Nicola Glorioso Alan S Go Omri Gottesman Jürgen Gräßler Harald Grallert Niels Grarup Yu-Mei Gu Linda Broer Annelies C Ham Torben Hansen Tamara B Harris Catharina A Hartman Maija Hassinen Nicholas Hastie Andrew T Hattersley Andrew C Heath Anjali K Henders Dena Hernandez Hans Hillege Oddgeir Holmen Kees G Hovingh Jennie Hui Lise L Husemoen Nina Hutri-Kähönen Pirro G Hysi Thomas Illig Philip L De Jager Shapour Jalilzadeh Torben Jørgensen J Wouter Jukema Markus Juonala Stavroula Kanoni Maria Karaleftheri Kay Tee Khaw Leena Kinnunen Steven J Kittner Wolfgang Koenig Ivana Kolcic Peter Kovacs Nikolaj T Krarup Wolfgang Kratzer Janine Krüger Diana Kuh Meena Kumari Theodosios Kyriakou Claudia Langenberg Lars Lannfelt Chiara Lanzani Vaneet Lotay Lenore J Launer Karin Leander Jaana Lindström Allan Linneberg Yan-Ping Liu Stéphane Lobbens Robert Luben Valeriya Lyssenko Satu Männistö Patrik K Magnusson Wendy L McArdle Cristina Menni Sigrun Merger Lili Milani Grant W Montgomery Andrew P Morris Narisu Narisu Mari Nelis Ken K Ong Aarno Palotie Louis Pérusse Irene Pichler Maria G Pilia Anneli Pouta Myriam Rheinberger Rasmus Ribel-Madsen Marcus Richards Kenneth M Rice Treva K Rice Carlo Rivolta Veikko Salomaa Alan R Sanders Mark A Sarzynski Salome Scholtens Robert A Scott William R Scott Sylvain Sebert Sebanti Sengupta Bengt Sennblad Thomas Seufferlein Angela Silveira P Eline Slagboom Jan H Smit Thomas H Sparsø Kathleen Stirrups Ronald P Stolk Heather M Stringham Morris A Swertz Amy J Swift Ann-Christine Syvänen Sian-Tsung Tan Barbara Thorand Anke Tönjes Angelo Tremblay Emmanouil Tsafantakis Peter J van der Most Uwe Völker Marie-Claude Vohl Judith M Vonk Melanie Waldenberger Ryan W Walker Roman Wennauer Elisabeth Widén Gonneke Willemsen Tom Wilsgaard Alan F Wright M Carola Zillikens Suzanne C van Dijk Natasja M van Schoor Folkert W Asselbergs Paul I W de Bakker Jacques S Beckmann John Beilby David A Bennett Richard N Bergman Sven Bergmann Carsten A Böger Bernhard O Boehm Eric Boerwinkle Dorret I Boomsma Stefan R Bornstein Erwin P Bottinger Claude Bouchard John C Chambers Stephen J Chanock Daniel I Chasman Francesco Cucca Daniele Cusi George Dedoussis Jeanette Erdmann Johan G Eriksson Denis A Evans Ulf de Faire Martin Farrall Luigi Ferrucci Ian Ford Lude Franke Paul W Franks Philippe Froguel Ron T Gansevoort Christian Gieger Henrik Grönberg Vilmundur Gudnason Ulf Gyllensten Per Hall Anders Hamsten Pim van der Harst Caroline Hayward Markku Heliövaara Christian Hengstenberg Andrew A Hicks Aroon Hingorani Albert Hofman Frank Hu Heikki V Huikuri Kristian Hveem Alan L James Joanne M Jordan Antti Jula Mika Kähönen Eero Kajantie Sekar Kathiresan Lambertus A L M Kiemeney Mika Kivimaki Paul B Knekt Heikki A Koistinen Jaspal S Kooner Seppo Koskinen Johanna Kuusisto Winfried Maerz Nicholas G Martin Markku Laakso Timo A Lakka Terho Lehtimäki Guillaume Lettre Douglas F Levinson Lars Lind Marja-Liisa Lokki Pekka Mäntyselkä Mads Melbye Andres Metspalu Braxton D Mitchell Frans L Moll Jeffrey C Murray Arthur W Musk Markku S Nieminen Inger Njølstad Claes Ohlsson Albertine J Oldehinkel Ben A Oostra Lyle J Palmer James S Pankow Gerard Pasterkamp Nancy L Pedersen Oluf Pedersen Brenda W Penninx Markus Perola Annette Peters Ozren Polašek Peter P Pramstaller Bruce M Psaty Lu Qi Thomas Quertermous Olli T Raitakari Tuomo Rankinen Rainer Rauramaa Paul M Ridker John D Rioux Fernando Rivadeneira Jerome I Rotter Igor Rudan Hester M den Ruijter Juha Saltevo Naveed Sattar Heribert Schunkert Peter E H Schwarz Alan R Shuldiner Juha Sinisalo Harold Snieder Thorkild I A Sørensen Tim D Spector Jan A Staessen Bandinelli Stefania Unnur Thorsteinsdottir Michael Stumvoll Jean-Claude Tardif Elena Tremoli Jaakko Tuomilehto André G Uitterlinden Matti Uusitupa André L M Verbeek Sita H Vermeulen Jorma S Viikari Veronique Vitart Henry Völzke Peter Vollenweider Gérard Waeber Mark Walker Henri Wallaschofski Nicholas J Wareham Hugh Watkins Eleftheria Zeggini Aravinda Chakravarti Deborah J Clegg L Adrienne Cupples Penny Gordon-Larsen Cashell E Jaquish D C Rao Goncalo R Abecasis Themistocles L Assimes Inês Barroso Sonja I Berndt Michael Boehnke Panos Deloukas Caroline S Fox Leif C Groop David J Hunter Erik Ingelsson Robert C Kaplan Mark I McCarthy Karen L Mohlke Jeffrey R O'Connell David Schlessinger David P Strachan Kari Stefansson Cornelia M van Duijn Joel N Hirschhorn Cecilia M Lindgren Iris M Heid Kari E North Ingrid B Borecki Zoltán Kutalik Ruth J F Loos

PLoS Genet 2015 Oct 1;11(10):e1005378. Epub 2015 Oct 1.

MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, United Kingdom; The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York, United States of America; The Department of Preventive Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York, United States of America; The Genetics of Obesity and Related Metabolic Traits Program, The Icahn School of Medicine at Mount Sinai, New York, New York, United States of America; The Mindich Child Health and Development Institute, The Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.

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October 2015

Hydroxysteroid (17β)-dehydrogenase 1-deficient female mice present with normal puberty onset but are severely subfertile due to a defect in luteinization and progesterone production.

FASEB J 2015 Sep 27;29(9):3806-16. Epub 2015 May 27.

*Department of Physiology, Institute of Biomedicine, and Turku Center for Disease Modeling, University of Turku, Turku, Finland; and Institute of Medicine, The Sahlgrenska Academy, Gothenburg University, Gothenburg, Sweden

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September 2015

Measurement of a Comprehensive Sex Steroid Profile in Rodent Serum by High-Sensitive Gas Chromatography-Tandem Mass Spectrometry.

Endocrinology 2015 Jul 9;156(7):2492-502. Epub 2015 Apr 9.

Centre for Bone and Arthritis Research (M.E.N., L.V., M.K.L., S.H.W., A.E.B., H.H.F., M.P., C.O.), Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Wallenberg Laboratory for Cardiovascular and Metabolic Research (Å.T.), Institute of Medicine, Department of Physiology (A.B., M.M., E.S.-V.), Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg SE-413 45, Sweden; Department of Clinical Chemistry (M.E.N., A.-K.N., H.R.), Sahlgrenska University Hospital, Gothenburg SE-413 45, Sweden; and Department of Physiology (M.P.), Institute of Biomedicine and Turku Center for Disease Modeling, University of Turku, Turku FI-20014, Finland.

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July 2015

Sleep Duration and Disturbances Were Associated With Testosterone Level, Muscle Mass, and Muscle Strength--A Cross-Sectional Study in 1274 Older Men.

J Am Med Dir Assoc 2015 Jul 8;16(7):630.e1-6. Epub 2015 May 8.

Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, China.

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July 2015

Genetic studies of body mass index yield new insights for obesity biology.

Authors:
Adam E Locke Bratati Kahali Sonja I Berndt Anne E Justice Tune H Pers Felix R Day Corey Powell Sailaja Vedantam Martin L Buchkovich Jian Yang Damien C Croteau-Chonka Tonu Esko Tove Fall Teresa Ferreira Stefan Gustafsson Zoltán Kutalik Jian'an Luan Reedik Mägi Joshua C Randall Thomas W Winkler Andrew R Wood Tsegaselassie Workalemahu Jessica D Faul Jennifer A Smith Jing Hua Zhao Wei Zhao Jin Chen Rudolf Fehrmann Åsa K Hedman Juha Karjalainen Ellen M Schmidt Devin Absher Najaf Amin Denise Anderson Marian Beekman Jennifer L Bolton Jennifer L Bragg-Gresham Steven Buyske Ayse Demirkan Guohong Deng Georg B Ehret Bjarke Feenstra Mary F Feitosa Krista Fischer Anuj Goel Jian Gong Anne U Jackson Stavroula Kanoni Marcus E Kleber Kati Kristiansson Unhee Lim Vaneet Lotay Massimo Mangino Irene Mateo Leach Carolina Medina-Gomez Sarah E Medland Michael A Nalls Cameron D Palmer Dorota Pasko Sonali Pechlivanis Marjolein J Peters Inga Prokopenko Dmitry Shungin Alena Stančáková Rona J Strawbridge Yun Ju Sung Toshiko Tanaka Alexander Teumer Stella Trompet Sander W van der Laan Jessica van Setten Jana V Van Vliet-Ostaptchouk Zhaoming Wang Loïc Yengo Weihua Zhang Aaron Isaacs Eva Albrecht Johan Ärnlöv Gillian M Arscott Antony P Attwood Stefania Bandinelli Amy Barrett Isabelita N Bas Claire Bellis Amanda J Bennett Christian Berne Roza Blagieva Matthias Blüher Stefan Böhringer Lori L Bonnycastle Yvonne Böttcher Heather A Boyd Marcel Bruinenberg Ida H Caspersen Yii-Der Ida Chen Robert Clarke E Warwick Daw Anton J M de Craen Graciela Delgado Maria Dimitriou Alex S F Doney Niina Eklund Karol Estrada Elodie Eury Lasse Folkersen Ross M Fraser Melissa E Garcia Frank Geller Vilmantas Giedraitis Bruna Gigante Alan S Go Alain Golay Alison H Goodall Scott D Gordon Mathias Gorski Hans-Jörgen Grabe Harald Grallert Tanja B Grammer Jürgen Gräßler Henrik Grönberg Christopher J Groves Gaëlle Gusto Jeffrey Haessler Per Hall Toomas Haller Goran Hallmans Catharina A Hartman Maija Hassinen Caroline Hayward Nancy L Heard-Costa Quinta Helmer Christian Hengstenberg Oddgeir Holmen Jouke-Jan Hottenga Alan L James Janina M Jeff Åsa Johansson Jennifer Jolley Thorhildur Juliusdottir Leena Kinnunen Wolfgang Koenig Markku Koskenvuo Wolfgang Kratzer Jaana Laitinen Claudia Lamina Karin Leander Nanette R Lee Peter Lichtner Lars Lind Jaana Lindström Ken Sin Lo Stéphane Lobbens Roberto Lorbeer Yingchang Lu François Mach Patrik K E Magnusson Anubha Mahajan Wendy L McArdle Stela McLachlan Cristina Menni Sigrun Merger Evelin Mihailov Lili Milani Alireza Moayyeri Keri L Monda Mario A Morken Antonella Mulas Gabriele Müller Martina Müller-Nurasyid Arthur W Musk Ramaiah Nagaraja Markus M Nöthen Ilja M Nolte Stefan Pilz Nigel W Rayner Frida Renstrom Rainer Rettig Janina S Ried Stephan Ripke Neil R Robertson Lynda M Rose Serena Sanna Hubert Scharnagl Salome Scholtens Fredrick R Schumacher William R Scott Thomas Seufferlein Jianxin Shi Albert Vernon Smith Joanna Smolonska Alice V Stanton Valgerdur Steinthorsdottir Kathleen Stirrups Heather M Stringham Johan Sundström Morris A Swertz Amy J Swift Ann-Christine Syvänen Sian-Tsung Tan Bamidele O Tayo Barbara Thorand Gudmar Thorleifsson Jonathan P Tyrer Hae-Won Uh Liesbeth Vandenput Frank C Verhulst Sita H Vermeulen Niek Verweij Judith M Vonk Lindsay L Waite Helen R Warren Dawn Waterworth Michael N Weedon Lynne R Wilkens Christina Willenborg Tom Wilsgaard Mary K Wojczynski Andrew Wong Alan F Wright Qunyuan Zhang Eoin P Brennan Murim Choi Zari Dastani Alexander W Drong Per Eriksson Anders Franco-Cereceda Jesper R Gådin Ali G Gharavi Michael E Goddard Robert E Handsaker Jinyan Huang Fredrik Karpe Sekar Kathiresan Sarah Keildson Krzysztof Kiryluk Michiaki Kubo Jong-Young Lee Liming Liang Richard P Lifton Baoshan Ma Steven A McCarroll Amy J McKnight Josine L Min Miriam F Moffatt Grant W Montgomery Joanne M Murabito George Nicholson Dale R Nyholt Yukinori Okada John R B Perry Rajkumar Dorajoo Eva Reinmaa Rany M Salem Niina Sandholm Robert A Scott Lisette Stolk Atsushi Takahashi Toshihiro Tanaka Ferdinand M van 't Hooft Anna A E Vinkhuyzen Harm-Jan Westra Wei Zheng Krina T Zondervan Andrew C Heath Dominique Arveiler Stephan J L Bakker John Beilby Richard N Bergman John Blangero Pascal Bovet Harry Campbell Mark J Caulfield Giancarlo Cesana Aravinda Chakravarti Daniel I Chasman Peter S Chines Francis S Collins Dana C Crawford L Adrienne Cupples Daniele Cusi John Danesh Ulf de Faire Hester M den Ruijter Anna F Dominiczak Raimund Erbel Jeanette Erdmann Johan G Eriksson Martin Farrall Stephan B Felix Ele Ferrannini Jean Ferrières Ian Ford Nita G Forouhi Terrence Forrester Oscar H Franco Ron T Gansevoort Pablo V Gejman Christian Gieger Omri Gottesman Vilmundur Gudnason Ulf Gyllensten Alistair S Hall Tamara B Harris Andrew T Hattersley Andrew A Hicks Lucia A Hindorff Aroon D Hingorani Albert Hofman Georg Homuth G Kees Hovingh Steve E Humphries Steven C Hunt Elina Hyppönen Thomas Illig Kevin B Jacobs Marjo-Riitta Jarvelin Karl-Heinz Jöckel Berit Johansen Pekka Jousilahti J Wouter Jukema Antti M Jula Jaakko Kaprio John J P Kastelein Sirkka M Keinanen-Kiukaanniemi Lambertus A Kiemeney Paul Knekt Jaspal S Kooner Charles Kooperberg Peter Kovacs Aldi T Kraja Meena Kumari Johanna Kuusisto Timo A Lakka Claudia Langenberg Loic Le Marchand Terho Lehtimäki Valeriya Lyssenko Satu Männistö André Marette Tara C Matise Colin A McKenzie Barbara McKnight Frans L Moll Andrew D Morris Andrew P Morris Jeffrey C Murray Mari Nelis Claes Ohlsson Albertine J Oldehinkel Ken K Ong Pamela A F Madden Gerard Pasterkamp John F Peden Annette Peters Dirkje S Postma Peter P Pramstaller Jackie F Price Lu Qi Olli T Raitakari Tuomo Rankinen D C Rao Treva K Rice Paul M Ridker John D Rioux Marylyn D Ritchie Igor Rudan Veikko Salomaa Nilesh J Samani Jouko Saramies Mark A Sarzynski Heribert Schunkert Peter E H Schwarz Peter Sever Alan R Shuldiner Juha Sinisalo Ronald P Stolk Konstantin Strauch Anke Tönjes David-Alexandre Trégouët Angelo Tremblay Elena Tremoli Jarmo Virtamo Marie-Claude Vohl Uwe Völker Gérard Waeber Gonneke Willemsen Jacqueline C Witteman M Carola Zillikens Linda S Adair Philippe Amouyel Folkert W Asselbergs Themistocles L Assimes Murielle Bochud Bernhard O Boehm Eric Boerwinkle Stefan R Bornstein Erwin P Bottinger Claude Bouchard Stéphane Cauchi John C Chambers Stephen J Chanock Richard S Cooper Paul I W de Bakker George Dedoussis Luigi Ferrucci Paul W Franks Philippe Froguel Leif C Groop Christopher A Haiman Anders Hamsten Jennie Hui David J Hunter Kristian Hveem Robert C Kaplan Mika Kivimaki Diana Kuh Markku Laakso Yongmei Liu Nicholas G Martin Winfried März Mads Melbye Andres Metspalu Susanne Moebus Patricia B Munroe Inger Njølstad Ben A Oostra Colin N A Palmer Nancy L Pedersen Markus Perola Louis Pérusse Ulrike Peters Chris Power Thomas Quertermous Rainer Rauramaa Fernando Rivadeneira Timo E Saaristo Danish Saleheen Naveed Sattar Eric E Schadt David Schlessinger P Eline Slagboom Harold Snieder Tim D Spector Unnur Thorsteinsdottir Michael Stumvoll Jaakko Tuomilehto André G Uitterlinden Matti Uusitupa Pim van der Harst Mark Walker Henri Wallaschofski Nicholas J Wareham Hugh Watkins David R Weir H-Erich Wichmann James F Wilson Pieter Zanen Ingrid B Borecki Panos Deloukas Caroline S Fox Iris M Heid Jeffrey R O'Connell David P Strachan Kari Stefansson Cornelia M van Duijn Gonçalo R Abecasis Lude Franke Timothy M Frayling Mark I McCarthy Peter M Visscher André Scherag Cristen J Willer Michael Boehnke Karen L Mohlke Cecilia M Lindgren Jacques S Beckmann Inês Barroso Kari E North Erik Ingelsson Joel N Hirschhorn Ruth J F Loos Elizabeth K Speliotes

Nature 2015 Feb;518(7538):197-206

Department of Internal Medicine, Division of Gastroenterology, and Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan 48109, USA.

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February 2015

DHEA and mortality: what is the nature of the association?

J Steroid Biochem Mol Biol 2015 Jan 2;145:248-53. Epub 2014 Apr 2.

Wallenberg Laboratory for Cardiovascular and Metabolic Research, Institute of Medicine, Sahlgrenska University Hospital, University of Gothenburg, Bruna Stråket 16, S-413 45 Gothenburg, Sweden. Electronic address:

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January 2015

Sex steroid actions in male bone.

Endocr Rev 2014 Dec 9;35(6):906-60. Epub 2014 Sep 9.

Clinical and Experimental Endocrinology (D.V.) and Gerontology and Geriatrics (M.R.L., E.G.), Department of Clinical and Experimental Medicine; Laboratory of Molecular Endocrinology, Department of Cellular and Molecular Medicine (M.R.L., F.C.); and Centre for Metabolic Bone Diseases (D.V., M.R.L., E.G.), KU Leuven, B-3000 Leuven, Belgium; and Center for Bone and Arthritis Research (M.K.L., L.V., A.E.B., C.O.), Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, 413 45 Gothenburg, Sweden.

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December 2014

Dehydroepiandrosterone and its sulfate predict the 5-year risk of coronary heart disease events in elderly men.

J Am Coll Cardiol 2014 Oct 21;64(17):1801-10. Epub 2014 Oct 21.

Centre for Bone and Arthritis Research, Institute of Medicine, University of Gothenburg, Gothenburg, Sweden.

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October 2014

Serum estradiol levels are inversely associated with cortical porosity in older men.

J Clin Endocrinol Metab 2014 Jul 2;99(7):E1322-6. Epub 2014 Apr 2.

Centre for Bone and Arthritis Research (L.V., M.L., D.S., M.E.N., D.M., C.O.), Department of Geriatric Medicine (M.L., D.S., D.M.), Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, SE-413 45 Gothenburg, Sweden; Department of Clinical Chemistry (M.E.N.), Sahlgrenska University Hospital, SE-413 45 Gothenburg, Sweden; and Clinical and Molecular Osteoporosis Research Unit (M.K.K.), Department of Clinical Sciences, Lund University, and Department of Orthopaedics (M.K.K.), Malmö University Hospital, S-205 02 Malmö, Sweden.

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July 2014

Serum estradiol associates with blood hemoglobin in elderly men: the MrOS Sweden study.

J Clin Endocrinol Metab 2014 Jul 14;99(7):2549-56. Epub 2014 Apr 14.

Section of Hematology and Coagulation, Department of Internal Medicine, Institute of Medicine (C.L., H.N.-E.), Department of Clinical Chemistry and Transfusion Medicine (S.J.), and Center for Bone and Arthritis Research (CBAR), Geriatric Medicine at the Institute of Medicine (H.J., V.S., M.L., D.M.), Sahlgrenska Academy at the University of Gothenburg, 413 45 Gothenburg, Sweden; Clinical and Molecular Osteoporosis Research Unit (M.K.K.), Department of Clinical Sciences and Orthopaedics, Lund University, SE-20502 Malmö, Sweden; Department of Family and Preventative Medicine (E.B.-C.), University of California, San Diego, California 92093; and CBAR (L.V., C.O.), Department of Internal Medicine and Clinical Nutrition, at the Institute of Medicine, Sahlgrenska Academy at the University of Gothenburg, SE-411 45 Gothenburg, Sweden.

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July 2014

Genome-wide association studies on serum sex steroid levels.

Mol Cell Endocrinol 2014 Jan 28;382(1):758-766. Epub 2013 Mar 28.

Centre for Bone and Arthritis Research, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

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January 2014

Genetics of endocrine disorders in the era of genome-wide association studies.

Mol Cell Endocrinol 2014 Jan 3;382(1):725. Epub 2013 Jul 3.

Centre for Bone and Arthritis Research, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, 413 45 Gothenburg, Sweden. Electronic address:

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January 2014

Sex steroids and bone health in men.

Bonekey Rep 2012 10;1. Epub 2012 Jan 10.

Centre for Bone and Arthritis Research, Department of Internal Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg , Göteborg, Sweden .

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August 2013

Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders.

Authors:
Marcel den Hoed Mark Eijgelsheim Tõnu Esko Bianca J J M Brundel David S Peal David M Evans Ilja M Nolte Ayellet V Segrè Hilma Holm Robert E Handsaker Harm-Jan Westra Toby Johnson Aaron Isaacs Jian Yang Alicia Lundby Jing Hua Zhao Young Jin Kim Min Jin Go Peter Almgren Murielle Bochud Gabrielle Boucher Marilyn C Cornelis Daniel Gudbjartsson David Hadley Pim van der Harst Caroline Hayward Martin den Heijer Wilmar Igl Anne U Jackson Zoltán Kutalik Jian'an Luan John P Kemp Kati Kristiansson Claes Ladenvall Mattias Lorentzon May E Montasser Omer T Njajou Paul F O'Reilly Sandosh Padmanabhan Beate St Pourcain Tuomo Rankinen Perttu Salo Toshiko Tanaka Nicholas J Timpson Veronique Vitart Lindsay Waite William Wheeler Weihua Zhang Harmen H M Draisma Mary F Feitosa Kathleen F Kerr Penelope A Lind Evelin Mihailov N Charlotte Onland-Moret Ci Song Michael N Weedon Weijia Xie Loic Yengo Devin Absher Christine M Albert Alvaro Alonso Dan E Arking Paul I W de Bakker Beverley Balkau Cristina Barlassina Paola Benaglio Joshua C Bis Nabila Bouatia-Naji Søren Brage Stephen J Chanock Peter S Chines Mina Chung Dawood Darbar Christian Dina Marcus Dörr Paul Elliott Stephan B Felix Krista Fischer Christian Fuchsberger Eco J C de Geus Philippe Goyette Vilmundur Gudnason Tamara B Harris Anna-Liisa Hartikainen Aki S Havulinna Susan R Heckbert Andrew A Hicks Albert Hofman Suzanne Holewijn Femke Hoogstra-Berends Jouke-Jan Hottenga Majken K Jensen Asa Johansson Juhani Junttila Stefan Kääb Bart Kanon Shamika Ketkar Kay-Tee Khaw Joshua W Knowles Angrad S Kooner Jan A Kors Meena Kumari Lili Milani Päivi Laiho Edward G Lakatta Claudia Langenberg Maarten Leusink Yongmei Liu Robert N Luben Kathryn L Lunetta Stacey N Lynch Marcello R P Markus Pedro Marques-Vidal Irene Mateo Leach Wendy L McArdle Steven A McCarroll Sarah E Medland Kathryn A Miller Grant W Montgomery Alanna C Morrison Martina Müller-Nurasyid Pau Navarro Mari Nelis Jeffrey R O'Connell Christopher J O'Donnell Ken K Ong Anne B Newman Annette Peters Ozren Polasek Anneli Pouta Peter P Pramstaller Bruce M Psaty Dabeeru C Rao Susan M Ring Elizabeth J Rossin Diana Rudan Serena Sanna Robert A Scott Jaban S Sehmi Stephen Sharp Jordan T Shin Andrew B Singleton Albert V Smith Nicole Soranzo Tim D Spector Chip Stewart Heather M Stringham Kirill V Tarasov André G Uitterlinden Liesbeth Vandenput Shih-Jen Hwang John B Whitfield Cisca Wijmenga Sarah H Wild Gonneke Willemsen James F Wilson Jacqueline C M Witteman Andrew Wong Quenna Wong Yalda Jamshidi Paavo Zitting Jolanda M A Boer Dorret I Boomsma Ingrid B Borecki Cornelia M van Duijn Ulf Ekelund Nita G Forouhi Philippe Froguel Aroon Hingorani Erik Ingelsson Mika Kivimaki Richard A Kronmal Diana Kuh Lars Lind Nicholas G Martin Ben A Oostra Nancy L Pedersen Thomas Quertermous Jerome I Rotter Yvonne T van der Schouw W M Monique Verschuren Mark Walker Demetrius Albanes David O Arnar Themistocles L Assimes Stefania Bandinelli Michael Boehnke Rudolf A de Boer Claude Bouchard W L Mark Caulfield John C Chambers Gary Curhan Daniele Cusi Johan Eriksson Luigi Ferrucci Wiek H van Gilst Nicola Glorioso Jacqueline de Graaf Leif Groop Ulf Gyllensten Wen-Chi Hsueh Frank B Hu Heikki V Huikuri David J Hunter Carlos Iribarren Bo Isomaa Marjo-Riitta Jarvelin Antti Jula Mika Kähönen Lambertus A Kiemeney Melanie M van der Klauw Jaspal S Kooner Peter Kraft Licia Iacoviello Terho Lehtimäki Marja-Liisa L Lokki Braxton D Mitchell Gerjan Navis Markku S Nieminen Claes Ohlsson Neil R Poulter Lu Qi Olli T Raitakari Eric B Rimm John D Rioux Federica Rizzi Igor Rudan Veikko Salomaa Peter S Sever Denis C Shields Alan R Shuldiner Juha Sinisalo Alice V Stanton Ronald P Stolk David P Strachan Jean-Claude Tardif Unnur Thorsteinsdottir Jaako Tuomilehto Dirk J van Veldhuisen Jarmo Virtamo Jorma Viikari Peter Vollenweider Gérard Waeber Elisabeth Widen Yoon Shin Cho Jesper V Olsen Peter M Visscher Cristen Willer Lude Franke Jeanette Erdmann John R Thompson Arne Pfeufer Nona Sotoodehnia Christopher Newton-Cheh Patrick T Ellinor Bruno H Ch Stricker Andres Metspalu Markus Perola Jacques S Beckmann George Davey Smith Kari Stefansson Nicholas J Wareham Patricia B Munroe Ody C M Sibon David J Milan Harold Snieder Nilesh J Samani Ruth J F Loos

Nat Genet 2013 Jun 14;45(6):621-31. Epub 2013 Apr 14.

Medical Research Council MRC Epidemiology Unit, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, UK.

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June 2013

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.

Authors:
Sonja I Berndt Stefan Gustafsson Reedik Mägi Andrea Ganna Eleanor Wheeler Mary F Feitosa Anne E Justice Keri L Monda Damien C Croteau-Chonka Felix R Day Tõnu Esko Tove Fall Teresa Ferreira Davide Gentilini Anne U Jackson Jian'an Luan Joshua C Randall Sailaja Vedantam Cristen J Willer Thomas W Winkler Andrew R Wood Tsegaselassie Workalemahu Yi-Juan Hu Sang Hong Lee Liming Liang Dan-Yu Lin Josine L Min Benjamin M Neale Gudmar Thorleifsson Jian Yang Eva Albrecht Najaf Amin Jennifer L Bragg-Gresham Gemma Cadby Martin den Heijer Niina Eklund Krista Fischer Anuj Goel Jouke-Jan Hottenga Jennifer E Huffman Ivonne Jarick Åsa Johansson Toby Johnson Stavroula Kanoni Marcus E Kleber Inke R König Kati Kristiansson Zoltán Kutalik Claudia Lamina Cecile Lecoeur Guo Li Massimo Mangino Wendy L McArdle Carolina Medina-Gomez Martina Müller-Nurasyid Julius S Ngwa Ilja M Nolte Lavinia Paternoster Sonali Pechlivanis Markus Perola Marjolein J Peters Michael Preuss Lynda M Rose Jianxin Shi Dmitry Shungin 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Kraja Meena Kumari Kari Kuulasmaa Johanna Kuusisto Jaana H Laitinen Timo A Lakka Claudia Langenberg Lenore J Launer Lars Lind Jaana Lindström Jianjun Liu Antonio Liuzzi Marja-Liisa Lokki Mattias Lorentzon Pamela A Madden Patrik K Magnusson Paolo Manunta Diana Marek Winfried März Irene Mateo Leach Barbara McKnight Sarah E Medland Evelin Mihailov Lili Milani Grant W Montgomery Vincent Mooser Thomas W Mühleisen Patricia B Munroe Arthur W Musk Narisu Narisu Gerjan Navis George Nicholson Ellen A Nohr Ken K Ong Ben A Oostra Colin N A Palmer Aarno Palotie John F Peden Nancy Pedersen Annette Peters Ozren Polasek Anneli Pouta Peter P Pramstaller Inga Prokopenko Carolin Pütter Aparna Radhakrishnan Olli Raitakari Augusto Rendon Fernando Rivadeneira Igor Rudan Timo E Saaristo Jennifer G Sambrook Alan R Sanders Serena Sanna Jouko Saramies Sabine Schipf Stefan Schreiber Heribert Schunkert So-Youn Shin Stefano Signorini Juha Sinisalo Boris Skrobek Nicole Soranzo Alena Stančáková Klaus Stark Jonathan 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Nicholas G Martin Andres Metspalu Andrew D Morris Markku S Nieminen Inger Njølstad Claes Ohlsson Albertine J Oldehinkel Willem H Ouwehand Lyle J Palmer Brenda Penninx Chris Power Michael A Province Bruce M Psaty Lu Qi Rainer Rauramaa Paul M Ridker Samuli Ripatti Veikko Salomaa Nilesh J Samani Harold Snieder Thorkild I A Sørensen Timothy D Spector Kari Stefansson Anke Tönjes Jaakko Tuomilehto André G Uitterlinden Matti Uusitupa Pim van der Harst Peter Vollenweider Henri Wallaschofski Nicholas J Wareham Hugh Watkins H-Erich Wichmann James F Wilson Goncalo R Abecasis Themistocles L Assimes Inês Barroso Michael Boehnke Ingrid B Borecki Panos Deloukas Caroline S Fox Timothy Frayling Leif C Groop Talin Haritunian Iris M Heid David Hunter Robert C Kaplan Fredrik Karpe Miriam F Moffatt Karen L Mohlke Jeffrey R O'Connell Yudi Pawitan Eric E Schadt David Schlessinger Valgerdur Steinthorsdottir David P Strachan Unnur Thorsteinsdottir Cornelia M van Duijn Peter M Visscher Anna Maria Di Blasio Joel N Hirschhorn Cecilia M Lindgren Andrew P Morris David Meyre André Scherag Mark I McCarthy Elizabeth K Speliotes Kari E North Ruth J F Loos Erik Ingelsson

Nat Genet 2013 May 7;45(5):501-12. Epub 2013 Apr 7.

US Department of Health and Human Services, Division of Cancer Epidemiology and Genetics, National Cancer Institute, US National Institutes of Health, Bethesda, Maryland, USA.

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May 2013

A genome-wide association meta-analysis of circulating sex hormone-binding globulin reveals multiple Loci implicated in sex steroid hormone regulation.

Authors:
Andrea D Coviello Robin Haring Melissa Wellons Dhananjay Vaidya Terho Lehtimäki Sarah Keildson Kathryn L Lunetta Chunyan He Myriam Fornage Vasiliki Lagou Massimo Mangino N Charlotte Onland-Moret Brian Chen Joel Eriksson Melissa Garcia Yong Mei Liu Annemarie Koster Kurt Lohman Leo-Pekka Lyytikäinen Ann-Kristin Petersen Jennifer Prescott Lisette Stolk Liesbeth Vandenput Andrew R Wood Wei Vivian Zhuang Aimo Ruokonen Anna-Liisa Hartikainen Anneli Pouta Stefania Bandinelli Reiner Biffar Georg Brabant David G Cox Yuhui Chen Steven Cummings Luigi Ferrucci Marc J Gunter Susan E Hankinson Hannu Martikainen Albert Hofman Georg Homuth Thomas Illig John-Olov Jansson Andrew D Johnson David Karasik Magnus Karlsson Johannes Kettunen Douglas P Kiel Peter Kraft Jingmin Liu Östen Ljunggren Mattias Lorentzon Marcello Maggio Marcello R P Markus Dan Mellström Iva Miljkovic Daniel Mirel Sarah Nelson Laure Morin Papunen Petra H M Peeters Inga Prokopenko Leslie Raffel Martin Reincke Alex P Reiner Kathryn Rexrode Fernando Rivadeneira Stephen M Schwartz David Siscovick Nicole Soranzo Doris Stöckl Shelley Tworoger André G Uitterlinden Carla H van Gils Ramachandran S Vasan H-Erich Wichmann Guangju Zhai Shalender Bhasin Martin Bidlingmaier Stephen J Chanock Immaculata De Vivo Tamara B Harris David J Hunter Mika Kähönen Simin Liu Pamela Ouyang Tim D Spector Yvonne T van der Schouw Jorma Viikari Henri Wallaschofski Mark I McCarthy Timothy M Frayling Anna Murray Steve Franks Marjo-Riitta Järvelin Frank H de Jong Olli Raitakari Alexander Teumer Claes Ohlsson Joanne M Murabito John R B Perry

PLoS Genet 2012 19;8(7):e1002805. Epub 2012 Jul 19.

Section of Preventive Medicine and Epidemiology, Boston University School of Medicine, Boston, Massachusetts, United States of America.

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January 2013

Assessment of gene-by-sex interaction effect on bone mineral density.

J Bone Miner Res 2012 Oct;27(10):2051-64

Department of Biostatistics, Boston University School of Public Health, 801 Massachusetts Avenue CT3, Boston,MA 02118, USA.

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October 2012

The role of IGF-1 for fracture risk in men.

Front Endocrinol (Lausanne) 2012 27;3:51. Epub 2012 Mar 27.

Department of Internal Medicine, Institute of Medicine, Centre for Bone and Arthritis Research, Sahlgrenska Academy, University of Gothenburg Gothenburg, Sweden.

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July 2012

Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture.

Authors:
Karol Estrada Unnur Styrkarsdottir Evangelos Evangelou Yi-Hsiang Hsu Emma L Duncan Evangelia E Ntzani Ling Oei Omar M E Albagha Najaf Amin John P Kemp Daniel L Koller Guo Li Ching-Ti Liu Ryan L Minster Alireza Moayyeri Liesbeth Vandenput Dana Willner Su-Mei Xiao Laura M Yerges-Armstrong Hou-Feng Zheng Nerea Alonso Joel Eriksson Candace M Kammerer Stephen K Kaptoge Paul J Leo Gudmar Thorleifsson Scott G Wilson James F Wilson Ville Aalto Markku Alen Aaron K Aragaki Thor Aspelund Jacqueline R Center Zoe Dailiana David J Duggan Melissa Garcia Natàlia Garcia-Giralt Sylvie Giroux Göran Hallmans Lynne J Hocking Lise Bjerre Husted Karen A Jameson Rita Khusainova Ghi Su Kim Charles Kooperberg Theodora Koromila Marcin Kruk Marika Laaksonen Andrea Z Lacroix Seung Hun Lee Ping C Leung Joshua R Lewis Laura Masi Simona Mencej-Bedrac Tuan V Nguyen Xavier Nogues Millan S Patel Janez Prezelj Lynda M Rose Serena Scollen Kristin Siggeirsdottir Albert V Smith Olle Svensson Stella Trompet Olivia Trummer Natasja M van Schoor Jean Woo Kun Zhu Susana Balcells Maria Luisa Brandi Brendan M Buckley Sulin Cheng Claus Christiansen Cyrus Cooper George Dedoussis Ian Ford Morten Frost David Goltzman Jesús González-Macías Mika Kähönen Magnus Karlsson Elza Khusnutdinova Jung-Min Koh Panagoula Kollia Bente Lomholt Langdahl William D Leslie Paul Lips Östen Ljunggren Roman S Lorenc Janja Marc Dan Mellström Barbara Obermayer-Pietsch José M Olmos Ulrika Pettersson-Kymmer David M Reid José A Riancho Paul M Ridker François Rousseau P Eline Slagboom Nelson L S Tang Roser Urreizti Wim Van Hul Jorma Viikari María T Zarrabeitia Yurii S Aulchenko Martha Castano-Betancourt Elin Grundberg Lizbeth Herrera Thorvaldur Ingvarsson Hrefna Johannsdottir Tony Kwan Rui Li Robert Luben Carolina Medina-Gómez Stefan Th Palsson Sjur Reppe Jerome I Rotter Gunnar Sigurdsson Joyce B J van Meurs Dominique Verlaan Frances M K Williams Andrew R Wood Yanhua Zhou Kaare M Gautvik Tomi Pastinen Soumya Raychaudhuri Jane A Cauley Daniel I Chasman Graeme R Clark Steven R Cummings Patrick Danoy Elaine M Dennison Richard Eastell John A Eisman Vilmundur Gudnason Albert Hofman Rebecca D Jackson Graeme Jones J Wouter Jukema Kay-Tee Khaw Terho Lehtimäki Yongmei Liu Mattias Lorentzon Eugene McCloskey Braxton D Mitchell Kannabiran Nandakumar Geoffrey C Nicholson Ben A Oostra Munro Peacock Huibert A P Pols Richard L Prince Olli Raitakari Ian R Reid John Robbins Philip N Sambrook Pak Chung Sham Alan R Shuldiner Frances A Tylavsky Cornelia M van Duijn Nick J Wareham L Adrienne Cupples Michael J Econs David M Evans Tamara B Harris Annie Wai Chee Kung Bruce M Psaty Jonathan Reeve Timothy D Spector Elizabeth A Streeten M Carola Zillikens Unnur Thorsteinsdottir Claes Ohlsson David Karasik J Brent Richards Matthew A Brown Kari Stefansson André G Uitterlinden Stuart H Ralston John P A Ioannidis Douglas P Kiel Fernando Rivadeneira

Nat Genet 2012 Apr 15;44(5):491-501. Epub 2012 Apr 15.

Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands.

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April 2012

Low DHEAS levels are associated with depressive symptoms in elderly Chinese men: results from a large study.

Asian J Androl 2011 Nov 29;13(6):898-902. Epub 2011 Aug 29.

School of Public Health and Primary Care, The Chinese University of Hong Kong, Hong Kong, China.

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November 2011

Genetic determinants of serum testosterone concentrations in men.

PLoS Genet 2011 Oct 6;7(10):e1002313. Epub 2011 Oct 6.

Center for Bone and Arthritis Research, Department of Internal Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Sweden.

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October 2011

Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile.

Authors:
Tuomas O Kilpeläinen M Carola Zillikens Alena Stančákova Francis M Finucane Janina S Ried Claudia Langenberg Weihua Zhang Jacques S Beckmann Jian'an Luan Liesbeth Vandenput Unnur Styrkarsdottir Yanhua Zhou Albert Vernon Smith Jing-Hua Zhao Najaf Amin Sailaja Vedantam So-Youn Shin Talin Haritunians Mao Fu Mary F Feitosa Meena Kumari Bjarni V Halldorsson Emmi Tikkanen Massimo Mangino Caroline Hayward Ci Song Alice M Arnold Yurii S Aulchenko Ben A Oostra Harry Campbell L Adrienne Cupples Kathryn E Davis Angela Döring Gudny Eiriksdottir Karol Estrada José Manuel Fernández-Real Melissa Garcia Christian Gieger Nicole L Glazer Candace Guiducci Albert Hofman Steve E Humphries Bo Isomaa Leonie C Jacobs Antti Jula David Karasik Magnus K Karlsson Kay-Tee Khaw Lauren J Kim Mika Kivimäki Norman Klopp Brigitte Kühnel Johanna Kuusisto Yongmei Liu Osten Ljunggren Mattias Lorentzon Robert N Luben Barbara McKnight Dan Mellström Braxton D Mitchell Vincent Mooser José Maria Moreno Satu Männistö Jeffery R O'Connell Laura Pascoe Leena Peltonen Belén Peral Markus Perola Bruce M Psaty Veikko Salomaa David B Savage Robert K Semple Tatjana Skaric-Juric Gunnar Sigurdsson Kijoung S Song Timothy D Spector Ann-Christine Syvänen Philippa J Talmud Gudmar Thorleifsson Unnur Thorsteinsdottir André G Uitterlinden Cornelia M van Duijn Antonio Vidal-Puig Sarah H Wild Alan F Wright Deborah J Clegg Eric Schadt James F Wilson Igor Rudan Samuli Ripatti Ingrid B Borecki Alan R Shuldiner Erik Ingelsson John-Olov Jansson Robert C Kaplan Vilmundur Gudnason Tamara B Harris Leif Groop Douglas P Kiel Fernando Rivadeneira Mark Walker Inês Barroso Peter Vollenweider Gérard Waeber John C Chambers Jaspal S Kooner Nicole Soranzo Joel N Hirschhorn Kari Stefansson H-Erich Wichmann Claes Ohlsson Stephen O'Rahilly Nicholas J Wareham Elizabeth K Speliotes Caroline S Fox Markku Laakso Ruth J F Loos

Nat Genet 2011 Jun 26;43(8):753-60. Epub 2011 Jun 26.

Medical Research Council (MRC) Epidemiology Unit, Institute of Metabolic Science, Cambridge, UK.

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June 2011

Testosterone but not estradiol level is positively related to muscle strength and physical performance independent of muscle mass: a cross-sectional study in 1489 older men.

Eur J Endocrinol 2011 May 23;164(5):811-7. Epub 2011 Feb 23.

The S H Ho Centre of Gerontology and Geriatrics, The Chinese University of Hong Kong, Shatin, Hong Kong, People's Republic of China.

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May 2011

Older men with low serum IGF-1 have an increased risk of incident fractures: the MrOS Sweden study.

J Bone Miner Res 2011 Apr;26(4):865-72

Centre for Bone and Arthritis Research at the Sahlgrenska Academy, Institute of Medicine, University of Göteborg, Göteborg, Sweden.

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April 2011

Association of SRD5A2 variants and serum androstane-3alpha,17beta-diol glucuronide concentration in Chinese elderly men.

Clin Chem 2010 Nov 20;56(11):1742-9. Epub 2010 Sep 20.

Department of Chemical Pathology, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China.

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November 2010

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution.

Authors:
Iris M Heid Anne U Jackson Joshua C Randall Thomas W Winkler Lu Qi Valgerdur Steinthorsdottir Gudmar Thorleifsson M Carola Zillikens Elizabeth K Speliotes Reedik Mägi Tsegaselassie Workalemahu Charles C White Nabila Bouatia-Naji Tamara B Harris Sonja I Berndt Erik Ingelsson Cristen J Willer Michael N Weedon Jian'an Luan Sailaja Vedantam Tõnu Esko Tuomas O Kilpeläinen Zoltán Kutalik Shengxu Li Keri L Monda Anna L Dixon Christopher C Holmes Lee M Kaplan Liming Liang Josine L Min Miriam F Moffatt Cliona Molony George Nicholson Eric E Schadt Krina T Zondervan Mary F Feitosa Teresa Ferreira Hana Lango Allen Robert J Weyant Eleanor Wheeler Andrew R Wood Karol Estrada Michael E Goddard Guillaume Lettre Massimo Mangino Dale R Nyholt Shaun Purcell Albert Vernon Smith Peter M Visscher Jian Yang Steven A McCarroll James Nemesh Benjamin F Voight Devin Absher Najaf Amin Thor Aspelund Lachlan Coin Nicole L Glazer Caroline Hayward Nancy L Heard-Costa Jouke-Jan Hottenga Asa Johansson Toby Johnson Marika Kaakinen Karen Kapur Shamika Ketkar Joshua W Knowles Peter Kraft Aldi T Kraja Claudia Lamina Michael F Leitzmann Barbara McKnight Andrew P Morris Ken K Ong John R B Perry Marjolein J Peters Ozren Polasek Inga Prokopenko Nigel W Rayner Samuli Ripatti Fernando Rivadeneira Neil R Robertson Serena Sanna Ulla Sovio Ida Surakka Alexander Teumer Sophie van Wingerden Veronique Vitart Jing Hua Zhao Christine Cavalcanti-Proença Peter S Chines Eva Fisher Jennifer R Kulzer Cecile Lecoeur Narisu Narisu Camilla Sandholt Laura J Scott Kaisa Silander Klaus Stark Mari-Liis Tammesoo Tanya M Teslovich Nicholas John Timpson Richard M Watanabe Ryan Welch Daniel I Chasman Matthew N Cooper John-Olov Jansson Johannes Kettunen Robert W Lawrence Niina Pellikka Markus Perola Liesbeth Vandenput Helene Alavere Peter Almgren Larry D Atwood Amanda J Bennett Reiner Biffar Lori L Bonnycastle Stefan R Bornstein Thomas A Buchanan Harry Campbell Ian N M Day Mariano Dei Marcus Dörr Paul Elliott Michael R Erdos Johan G Eriksson Nelson B Freimer Mao Fu Stefan Gaget Eco J C Geus Anette P Gjesing Harald Grallert Jürgen Grässler Christopher J Groves Candace Guiducci Anna-Liisa Hartikainen Neelam Hassanali Aki S Havulinna Karl-Heinz Herzig Andrew A Hicks Jennie Hui Wilmar Igl Pekka Jousilahti Antti Jula Eero Kajantie Leena Kinnunen Ivana Kolcic Seppo Koskinen Peter Kovacs Heyo K Kroemer Vjekoslav Krzelj Johanna Kuusisto Kirsti Kvaloy Jaana Laitinen Olivier Lantieri G Mark Lathrop Marja-Liisa Lokki Robert N Luben Barbara Ludwig Wendy L McArdle Anne McCarthy Mario A Morken Mari Nelis Matt J Neville Guillaume Paré Alex N Parker John F Peden Irene Pichler Kirsi H Pietiläinen Carl G P Platou Anneli Pouta Martin Ridderstråle Nilesh J Samani Jouko Saramies Juha Sinisalo Jan H Smit Rona J Strawbridge Heather M Stringham Amy J Swift Maris Teder-Laving Brian Thomson Gianluca Usala Joyce B J van Meurs Gert-Jan van Ommen Vincent Vatin Claudia B Volpato Henri Wallaschofski G Bragi Walters Elisabeth Widen Sarah H Wild Gonneke Willemsen Daniel R Witte Lina Zgaga Paavo Zitting John P Beilby Alan L James Mika Kähönen Terho Lehtimäki Markku S Nieminen Claes Ohlsson Lyle J Palmer Olli Raitakari Paul M Ridker Michael Stumvoll Anke Tönjes Jorma Viikari Beverley Balkau Yoav Ben-Shlomo Richard N Bergman Heiner Boeing George Davey Smith Shah Ebrahim Philippe Froguel Torben Hansen Christian Hengstenberg Kristian Hveem Bo Isomaa Torben Jørgensen Fredrik Karpe Kay-Tee Khaw Markku Laakso Debbie A Lawlor Michel Marre Thomas Meitinger Andres Metspalu Kristian Midthjell Oluf Pedersen Veikko Salomaa Peter E H Schwarz Tiinamaija Tuomi Jaakko Tuomilehto Timo T Valle Nicholas J Wareham Alice M Arnold Jacques S Beckmann Sven Bergmann Eric Boerwinkle Dorret I Boomsma Mark J Caulfield Francis S Collins Gudny Eiriksdottir Vilmundur Gudnason Ulf Gyllensten Anders Hamsten Andrew T Hattersley Albert Hofman Frank B Hu Thomas Illig Carlos Iribarren Marjo-Riitta Jarvelin W H Linda Kao Jaakko Kaprio Lenore J Launer Patricia B Munroe Ben Oostra Brenda W Penninx Peter P Pramstaller Bruce M Psaty Thomas Quertermous Aila Rissanen Igor Rudan Alan R Shuldiner Nicole Soranzo Timothy D Spector Ann-Christine Syvanen Manuela Uda André Uitterlinden Henry Völzke Peter Vollenweider James F Wilson Jacqueline C Witteman Alan F Wright Gonçalo R Abecasis Michael Boehnke Ingrid B Borecki Panos Deloukas Timothy M Frayling Leif C Groop Talin Haritunians David J Hunter Robert C Kaplan Kari E North Jeffrey R O'Connell Leena Peltonen David Schlessinger David P Strachan Joel N Hirschhorn Themistocles L Assimes H-Erich Wichmann Unnur Thorsteinsdottir Cornelia M van Duijn Kari Stefansson L Adrienne Cupples Ruth J F Loos Inês Barroso Mark I McCarthy Caroline S Fox Karen L Mohlke Cecilia M Lindgren

Nat Genet 2010 Nov 10;42(11):949-60. Epub 2010 Oct 10.

Regensburg University Medical Center, Department of Epidemiology and Preventive Medicine, Regensburg, Germany.

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November 2010

Hundreds of variants clustered in genomic loci and biological pathways affect human height.

Authors:
Hana Lango Allen Karol Estrada Guillaume Lettre Sonja I Berndt Michael N Weedon Fernando Rivadeneira Cristen J Willer Anne U Jackson Sailaja Vedantam Soumya Raychaudhuri Teresa Ferreira Andrew R Wood Robert J Weyant Ayellet V Segrè Elizabeth K Speliotes Eleanor Wheeler Nicole Soranzo Ju-Hyun Park Jian Yang Daniel Gudbjartsson Nancy L Heard-Costa Joshua C Randall Lu Qi Albert Vernon Smith Reedik Mägi Tomi Pastinen Liming Liang Iris M Heid Jian'an Luan Gudmar Thorleifsson Thomas W Winkler Michael E Goddard Ken Sin Lo Cameron Palmer Tsegaselassie Workalemahu Yurii S Aulchenko Asa Johansson M Carola Zillikens Mary F Feitosa Tõnu Esko Toby Johnson Shamika Ketkar Peter Kraft Massimo Mangino Inga Prokopenko Devin Absher Eva Albrecht Florian Ernst Nicole L Glazer Caroline Hayward Jouke-Jan Hottenga Kevin B Jacobs Joshua W Knowles Zoltán Kutalik Keri L Monda Ozren Polasek Michael Preuss Nigel W Rayner Neil R Robertson Valgerdur Steinthorsdottir Jonathan P Tyrer Benjamin F Voight Fredrik Wiklund Jianfeng Xu Jing Hua Zhao Dale R Nyholt Niina Pellikka Markus Perola John R B Perry Ida Surakka Mari-Liis Tammesoo Elizabeth L Altmaier Najaf Amin Thor Aspelund Tushar Bhangale Gabrielle Boucher Daniel I Chasman Constance Chen Lachlan Coin Matthew N Cooper Anna L Dixon Quince Gibson Elin Grundberg Ke Hao M Juhani Junttila Lee M Kaplan Johannes Kettunen Inke R König Tony Kwan Robert W Lawrence Douglas F Levinson Mattias Lorentzon Barbara McKnight Andrew P Morris Martina Müller Julius Suh Ngwa Shaun Purcell Suzanne Rafelt Rany M Salem Erika Salvi Serena Sanna Jianxin Shi Ulla Sovio John R Thompson Michael C Turchin Liesbeth Vandenput Dominique J Verlaan Veronique Vitart Charles C White Andreas Ziegler Peter Almgren Anthony J Balmforth Harry Campbell Lorena Citterio Alessandro De Grandi Anna Dominiczak Jubao Duan Paul Elliott Roberto Elosua Johan G Eriksson Nelson B Freimer Eco J C Geus Nicola Glorioso Shen Haiqing Anna-Liisa Hartikainen Aki S Havulinna Andrew A Hicks Jennie Hui Wilmar Igl Thomas Illig Antti Jula Eero Kajantie Tuomas O Kilpeläinen Markku Koiranen Ivana Kolcic Seppo Koskinen Peter Kovacs Jaana Laitinen Jianjun Liu Marja-Liisa Lokki Ana Marusic Andrea Maschio Thomas Meitinger Antonella Mulas Guillaume Paré Alex N Parker John F Peden Astrid Petersmann Irene Pichler Kirsi H Pietiläinen Anneli Pouta Martin Ridderstråle Jerome I Rotter Jennifer G Sambrook Alan R Sanders Carsten Oliver Schmidt Juha Sinisalo Jan H Smit Heather M Stringham G Bragi Walters Elisabeth Widen Sarah H Wild Gonneke Willemsen Laura Zagato Lina Zgaga Paavo Zitting Helene Alavere Martin Farrall Wendy L McArdle Mari Nelis Marjolein J Peters Samuli Ripatti Joyce B J van Meurs Katja K Aben Kristin G Ardlie Jacques S Beckmann John P Beilby Richard N Bergman Sven Bergmann Francis S Collins Daniele Cusi Martin den Heijer Gudny Eiriksdottir Pablo V Gejman Alistair S Hall Anders Hamsten Heikki V Huikuri Carlos Iribarren Mika Kähönen Jaakko Kaprio Sekar Kathiresan Lambertus Kiemeney Thomas Kocher Lenore J Launer Terho Lehtimäki Olle Melander Tom H Mosley Arthur W Musk Markku S Nieminen Christopher J O'Donnell Claes Ohlsson Ben Oostra Lyle J Palmer Olli Raitakari Paul M Ridker John D Rioux Aila Rissanen Carlo Rivolta Heribert Schunkert Alan R Shuldiner David S Siscovick Michael Stumvoll Anke Tönjes Jaakko Tuomilehto Gert-Jan van Ommen Jorma Viikari Andrew C Heath Nicholas G Martin Grant W Montgomery Michael A Province Manfred Kayser Alice M Arnold Larry D Atwood Eric Boerwinkle Stephen J Chanock Panos Deloukas Christian Gieger Henrik Grönberg Per Hall Andrew T Hattersley Christian Hengstenberg Wolfgang Hoffman G Mark Lathrop Veikko Salomaa Stefan Schreiber Manuela Uda Dawn Waterworth Alan F Wright Themistocles L Assimes Inês Barroso Albert Hofman Karen L Mohlke Dorret I Boomsma Mark J Caulfield L Adrienne Cupples Jeanette Erdmann Caroline S Fox Vilmundur Gudnason Ulf Gyllensten Tamara B Harris Richard B Hayes Marjo-Riitta Jarvelin Vincent Mooser Patricia B Munroe Willem H Ouwehand Brenda W Penninx Peter P Pramstaller Thomas Quertermous Igor Rudan Nilesh J Samani Timothy D Spector Henry Völzke Hugh Watkins James F Wilson Leif C Groop Talin Haritunians Frank B Hu Robert C Kaplan Andres Metspalu Kari E North David Schlessinger Nicholas J Wareham David J Hunter Jeffrey R O'Connell David P Strachan H-Erich Wichmann Ingrid B Borecki Cornelia M van Duijn Eric E Schadt Unnur Thorsteinsdottir Leena Peltonen André G Uitterlinden Peter M Visscher Nilanjan Chatterjee Ruth J F Loos Michael Boehnke Mark I McCarthy Erik Ingelsson Cecilia M Lindgren Gonçalo R Abecasis Kari Stefansson Timothy M Frayling Joel N Hirschhorn

Nature 2010 Oct 29;467(7317):832-8. Epub 2010 Sep 29.

Genetics of Complex Traits, Peninsula College of Medicine and Dentistry, University of Exeter, Exeter EX1 2LU, UK.

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October 2010

Low serum levels of dehydroepiandrosterone sulfate predict all-cause and cardiovascular mortality in elderly Swedish men.

J Clin Endocrinol Metab 2010 Sep 7;95(9):4406-14. Epub 2010 Jul 7.

Wallenberg Laboratory for Cardiovascular Research, Institute of Medicine, University of Gothenburg, S-413 45 Gothenburg, Sweden.

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September 2010

Sex steroid metabolism in the regulation of bone health in men.

J Steroid Biochem Mol Biol 2010 Aug 31;121(3-5):582-8. Epub 2010 Mar 31.

Center for Bone and Arthritis Research at the Sahlgrenska Academy, Department of Internal Medicine, Institute of Medicine, University of Gothenburg, Gothenburg, Sweden.

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August 2010

Common genetic determinants of vitamin D insufficiency: a genome-wide association study.

Lancet 2010 Jul 10;376(9736):180-8. Epub 2010 Jun 10.

Division of Cardiology, Department of Medicine, Massachusetts General Hospital, Boston, MA 02114, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3086761PMC
July 2010

A semiparametric Bayesian approach for structural equation models.

Biom J 2010 Jun;52(3):314-32

Department of Statistics, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong.

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http://dx.doi.org/10.1002/bimj.200900135DOI Listing
June 2010

Serum estradiol is associated with lean mass in elderly Swedish men.

Eur J Endocrinol 2010 Apr 8;162(4):737-45. Epub 2010 Jan 8.

Division of Endocrinology, Department of Internal Medicine and Geriatrics, Institute of Medicine, University of Gothenburg, Center for Bone Research at the Sahlgrenska Academy, SE-41345 Gothenburg, Sweden.

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April 2010

Estrogens as regulators of bone health in men.

Nat Rev Endocrinol 2009 Aug 16;5(8):437-43. Epub 2009 Jun 16.

Center for Bone Research, Department of Internal Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

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August 2009

Low serum testosterone and estradiol predict mortality in elderly men.

J Clin Endocrinol Metab 2009 Jul 28;94(7):2482-8. Epub 2009 Apr 28.

Wallenberg Laboratory for Cardiovascular Research, Bruna Stråket 16, Sahlgrenska University Hospital, S-413 45 Göteborg, Sweden.

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July 2009

The role of estrogens for male bone health.

Eur J Endocrinol 2009 Jun 20;160(6):883-9. Epub 2009 Mar 20.

Center for Bone Research, Division of Endocrinology, Department of Internal Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, SE-41345 Gothenburg, Sweden.

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June 2009

Peripheral blood leukocyte distribution and body mass index are associated with the methylation pattern of the androgen receptor promoter.

Endocrine 2009 Apr 6;35(2):204-10. Epub 2009 Feb 6.

Division of Endocrinology, Departments of Internal Medicine and Geriatrics, Center for Bone Research at the Sahlgrenska Academy (CBS), University of Gothenburg, Gröna Stråket 8, 413 45 Gothenburg, Sweden.

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April 2009

Genetic variations in sex steroid-related genes as predictors of serum estrogen levels in men.

J Clin Endocrinol Metab 2009 Mar 30;94(3):1033-41. Epub 2008 Dec 30.

Center for Bone Research at the Sahlgrenska Academy, Department of Internal Medicine Gothenburg University, SE-413 45 Gothenburg, Sweden.

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March 2009

Comparable amounts of sex steroids are made outside the gonads in men and women: strong lesson for hormone therapy of prostate and breast cancer.

J Steroid Biochem Mol Biol 2009 Jan 27;113(1-2):52-6. Epub 2008 Nov 27.

Molecular Endocrinology and Oncology Research Center, Laval University Hospital Research Center (CRCHUL) 2705, Laurier Boulevard, Quebec City, Quebec, Canada G1V 4G2.

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January 2009

Older men with low serum estradiol and high serum SHBG have an increased risk of fractures.

J Bone Miner Res 2008 Oct;23(10):1552-60

Center for Bone Research, Sahlgrenska Academy, Department of Internal Medicine, University of Gothenburg, Gothenburg, Sweden.

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October 2008

The uridine diphosphate glucuronosyltransferase 2B15 D85Y and 2B17 deletion polymorphisms predict the glucuronidation pattern of androgens and fat mass in men.

J Clin Endocrinol Metab 2007 Dec 14;92(12):4878-82. Epub 2007 Aug 14.

Center for Bone Research at the Sahlgrenska Academy, Department of Internal Medicine, Göteborg University, SE-41345 Göteborg, Sweden.

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December 2007

Androgens and glucuronidated androgen metabolites are associated with metabolic risk factors in men.

J Clin Endocrinol Metab 2007 Nov 21;92(11):4130-7. Epub 2007 Aug 21.

Department of Internal Medicine, Gothenburg University, SE-41345 Gothenburg, Sweden.

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http://dx.doi.org/10.1210/jc.2007-0252DOI Listing
November 2007

Sex steroid levels and cortical bone size in young men are associated with a uridine diphosphate glucuronosyltransferase 2B7 polymorphism (H268Y).

J Clin Endocrinol Metab 2007 Sep 19;92(9):3697-704. Epub 2007 Jun 19.

Center for Bone Research at the Sahlgrenska Academy, Department of Internal Medicine, Gothenburg University, SE-41345 Gothenburg, Sweden.

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September 2007

Serum levels of specific glucuronidated androgen metabolites predict BMD and prostate volume in elderly men.

J Bone Miner Res 2007 Feb;22(2):220-7

Center for Bone Research, Departments of Internal Medicine and Geriatrics, The Sahlgrenska Academy at Göteborg University, Göteborg, Sweden.

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http://doi.wiley.com/10.1359/jbmr.061018
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February 2007

Reversing sex steroid deficiency and optimizing skeletal development in the adolescent with gonadal failure.

Endocr Dev 2005 ;8:150-65

Laboratory for Experimental Medicine and Endocrinology, Katholieke Universiteit Leuven, Leuven, Belgium.

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May 2005

Role of the androgen receptor in skeletal homeostasis: the androgen-resistant testicular feminized male mouse model.

J Bone Miner Res 2004 Sep 10;19(9):1462-70. Epub 2004 May 10.

Laboratory for Experimental Medicine and Endocrinology, Katholieke Universiteit Leuven, Leuven B-3000, Belgium.

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http://dx.doi.org/10.1359/JBMR.040505DOI Listing
September 2004

Androgens and bone.

Endocr Rev 2004 Jun;25(3):389-425

Laboratory for Experimental Medicine and Endocrinology, Katholieke Universiteit Leuven, Leuven, Belgium.

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June 2004