Publications by authors named "Lianjin Weng"

3 Publications

  • Page 1 of 1

Fabrication and wetting behaviour of micro/nanostructured mushroom-shaped silver pillar surface.

Nanotechnology 2020 Apr 3;31(17):175701. Epub 2020 Jan 3.

Institute of Chemical Engineering, Huaqiao University, Xiamen, 361021 People's Republic of China.

This manuscript presents a simple, one-step method for the fabrication of micro/nanostructured metal-based superhydrophobic surfaces via electroplating using stacked polycarbonate membranes with nanoscale and microscale pores as a template. The two-tiered mushroom-shaped silver pillar arrays include a top layer composed of nanopillars and a bottom layer composed of T-shaped micropillars. The presence of the re-entrant surface structures with a strong resistance pin the droplets to the cap's ridge and prevent water droplets from penetrating into the valleys of the rough surface, thus resulting in an increase in water contact angle (WCA). Compared with microstructured mushroom-shaped surfaces (WCA = 148°, sliding angle (SA) ∼ 26°) and nanostructured surfaces (WCA = 151.5°, SA ∼ 4.8°), the micro/nanostructured mushroom-shaped pillar arrays (WCA = 154.1°, SA ∼ 2°) exhibit remarkable superhydrophobic properties with high CA and low SA. This new micro/nanostructured surface will have a potential application in metal-based superhydrophobic materials.
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http://dx.doi.org/10.1088/1361-6528/ab674bDOI Listing
April 2020

Macranthol attenuates lipopolysaccharide-induced depressive-like behaviors by inhibiting neuroinflammation in prefrontal cortex.

Physiol Behav 2019 05 10;204:33-40. Epub 2019 Feb 10.

Department of Chemical and Pharmaceutical Engineering, Huaqiao University, Xiamen 361021, Fujian Province, PR China; Fujian Provincial Key Laboratory of Biochemical Technology, Huaqiao University, Xiamen 361021, Fujian Province, PR China. Electronic address:

Macranthol is a lignans natural product isolated from Illicium dunnianum Tutch. Our previous studies have shown that BDNF dependent signaling pathway activation was involved in the antidepressant-like effects of macranthol. However, it is not clear whether neuro-inflammation suppression is involved in the effects of macranthol. Therefore, the aim of this present study was to determine whether macranthol affected the neuro-inflammation system in lipopolysaccharide (LPS)-induced mice by measuring pro-inflammatory cytokines and CD11b. Macranthol was orally administrated for successive seven days before a single LPS injection. The behavioral evaluation showed that macranthol prevented LPS-induced depressive-like deficits both in sucrose preference test and forced swimming test. The elevation of serum and prefrontal cortex pro-inflammatory cytokines including interleukin-1β (IL-1β), interleukin-6 (IL-6) and tumor necrosis factor-α (TNF-α) was decreased by macranthol pretreatment. In addition, LPS induced the elevation of CD11b in the prefrontal cortex, which was also inhibited by macranthol. Last but not the least, the immunofluorescence found that the number of positive iba-1 cells was also decreased by macranthol. These findings suggest that macranthol could alleviate depressive-like behaviors in mice induced by LPS that are mediated, at least by suppressing microglia-related neuro-inflammation in the prefrontal cortex.
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http://dx.doi.org/10.1016/j.physbeh.2019.02.010DOI Listing
May 2019

Apigenin reverses depression-like behavior induced by chronic corticosterone treatment in mice.

Eur J Pharmacol 2016 Mar 27;774:50-4. Epub 2016 Jan 27.

Department of Chemical and Pharmaceutical Engineering, College of Chemical Engineering, Huaqiao University, No. 668, Jimei Road, Xiamen, Fujian Province, PR China.

Previous researches found that apigenin exerted antidepressant-like effects in rodents. However, it is unclear whether the neurotrophic system is involved in the antidepressant-like effects of apigenin. Our present study aimed to explore the neurotrophic related mechanism of apigenin in depressive-like mice induced by chronic corticosterone treatment. Mice were repeatedly injected with corticosterone (40 mg/kg) subcutaneously (s.c) once daily for consecutive 21 days. Apigenin (20 and 40 mg/kg) and fluoxetine (20 mg/kg) were administered 30 min prior to the corticosterone injection. The behavioral tests indicated that apigenin reversed the reduction of sucrose preference and the elevation of immobility time in mice induced by chronic corticosterone treatment. In addition, the increase in serum corticosterone levels and the decrease in hippocampal brain-derived neurotrophic factor (BDNF) levels in corticosterone-treated mice were also ameliorated by apigenin administration. Taken together, our findings intensively confirmed the antidepressant-like effects of apigenin and indicated that the antidepressant-like mechanism of apigenin was mediated, at least partly by up-regulation of BDNF levels in the hippocampus.
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http://dx.doi.org/10.1016/j.ejphar.2016.01.015DOI Listing
March 2016
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