Liang-Kee Goh

Liang-Kee Goh

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Liang-Kee Goh

Liang-Kee Goh

Publications by authors named "Liang-Kee Goh"

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28Publications

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Melanoma associated antigen (MAGE)-A3 promotes cell proliferation and chemotherapeutic drug resistance in gastric cancer.

Cell Oncol (Dordr) 2016 Apr 11;39(2):175-86. Epub 2016 Feb 11.

Department of Haematology-Oncology, National University Hospital, Level 7, NUHS Tower Block, 1E, Kent Ridge Road, Singapore, 119228, Singapore.

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http://dx.doi.org/10.1007/s13402-015-0261-5DOI Listing
April 2016

TOMM40 alterations in Alzheimer's disease over a 2-year follow-up period.

J Alzheimers Dis 2015 ;44(1):57-61

Department of Geriatric Medicine, Tan Tock Seng Hospital, Singapore, Singapore Institute of Geriatrics and Active Ageing, Tan Tock Seng Hospital, Singapore, Singapore.

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http://dx.doi.org/10.3233/JAD-141590DOI Listing
September 2015

Molecular characterization of hepatocarcinogenesis using mouse models.

Dis Model Mech 2015 Jul 5;8(7):743-53. Epub 2015 May 5.

Division of Cellular & Molecular Research, Humphrey Oei Institute of Cancer Research, National Cancer Centre, 11 Hospital Drive, 169610, Singapore Cancer and Stem Cell Biology Program, Duke-NUS Graduate Medical School, Duke-NUS Graduate Medical School, 8 College Road, 169857, Singapore Department of Biochemistry, National University of Singapore, 8 Medical Drive, 117597, Singapore

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http://dx.doi.org/10.1242/dmm.017624DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4486853PMC
July 2015

Regulatory crosstalk between lineage-survival oncogenes KLF5, GATA4 and GATA6 cooperatively promotes gastric cancer development.

Gut 2015 May 22;64(5):707-19. Epub 2014 Jul 22.

Cancer and Stem Cell Biology program, Duke-NUS Graduate Medical School Singapore, Singapore, Singapore Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore Cellular and Molecular Research, National Cancer Centre, Singapore, Singapore Genome Institute of Singapore, Singapore, Singapore.

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http://dx.doi.org/10.1136/gutjnl-2013-306596DOI Listing
May 2015

An integrative approach identified genes associated with drug response in gastric cancer.

Carcinogenesis 2015 Apr 5;36(4):441-51. Epub 2015 Mar 5.

Centre for Quantitative Medicine, Duke-National University of Singapore Graduate Medical School, Singapore, Singapore; Laboratory of Computational Biology, Cancer and Stem Cell Biology Program, Duke-National University of Singapore Graduate Medical School, Singapore, Singapore, Department of Medical Oncology, National Cancer Centre, Singapore, Singapore, Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore.

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http://dx.doi.org/10.1093/carcin/bgv014DOI Listing
April 2015

Hypoxia-inducible TAp73 supports tumorigenesis by regulating the angiogenic transcriptome.

Nat Cell Biol 2015 Apr 16;17(4):511-23. Epub 2015 Mar 16.

1] Division of Cellular &Molecular Research, Humphrey Oei Institute of Cancer Research, National Cancer Centre, Singapore 169610, Singapore [2] Cancer and Stem Cell Biology Program, Duke-NUS Graduate Medical School, Singapore 169857, Singapore [3] Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228, Singapore.

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http://dx.doi.org/10.1038/ncb3130DOI Listing
April 2015

Nanoscale chromatin profiling of gastric adenocarcinoma reveals cancer-associated cryptic promoters and somatically acquired regulatory elements.

Nat Commun 2014 Jul 10;5:4361. Epub 2014 Jul 10.

1] Cancer Therapeutics and Stratified Oncology, Genome Institute of Singapore, 60 Biopolis Street, Genome #02-01, Singapore 138672, Singapore [2] Cancer and Stem Cell Biology Program, Duke-NUS Graduate Medical School, 8 College Road, Singapore 169857, Singapore [3] Cancer Science Institute of Singapore, National University of Singapore, 14 Medical Drive, #12-01, Singapore 117599, Singapore [4] Cellular and Molecular Research, National Cancer Centre, 11 Hospital Drive, Singapore 169610, Singapore.

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http://dx.doi.org/10.1038/ncomms5361DOI Listing
July 2014

Optimizing Ventana chromogenic dual in-situ hybridization for mucinous epithelial ovarian cancer.

BMC Res Notes 2013 Dec 28;6:562. Epub 2013 Dec 28.

Cancer & Stem Cell Biology, Duke-National University of Singapore, Singapore, Singapore.

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http://dx.doi.org/10.1186/1756-0500-6-562DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3892083PMC
December 2013

Muscarinic cholinergic receptor (M2) plays a crucial role in the development of myopia in mice.

Dis Model Mech 2013 Sep 2;6(5):1146-58. Epub 2013 May 2.

Singapore Eye Research Institute, 11 Third Hospital Avenue, 168751 Singapore, Singapore.

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http://dx.doi.org/10.1242/dmm.010967DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759334PMC
September 2013

New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism.

Authors:
Momoko Horikoshi Hanieh Yaghootkar Dennis O Mook-Kanamori Ulla Sovio H Rob Taal Branwen J Hennig Jonathan P Bradfield Beate St Pourcain David M Evans Pimphen Charoen Marika Kaakinen Diana L Cousminer Terho Lehtimäki Eskil Kreiner-Møller Nicole M Warrington Mariona Bustamante Bjarke Feenstra Diane J Berry Elisabeth Thiering Thiemo Pfab Sheila J Barton Beverley M Shields Marjan Kerkhof Elisabeth M van Leeuwen Anthony J Fulford Zoltán Kutalik Jing Hua Zhao Marcel den Hoed Anubha Mahajan Virpi Lindi Liang-Kee Goh Jouke-Jan Hottenga Ying Wu Olli T Raitakari Marie N Harder Aline Meirhaeghe Ioanna Ntalla Rany M Salem Karen A Jameson Kaixin Zhou Dorota M Monies Vasiliki Lagou Mirna Kirin Jani Heikkinen Linda S Adair Fowzan S Alkuraya Ali Al-Odaib Philippe Amouyel Ehm Astrid Andersson Amanda J Bennett Alexandra I F Blakemore Jessica L Buxton Jean Dallongeville Shikta Das Eco J C de Geus Xavier Estivill Claudia Flexeder Philippe Froguel Frank Geller Keith M Godfrey Frédéric Gottrand Christopher J Groves Torben Hansen Joel N Hirschhorn Albert Hofman Mads V Hollegaard David M Hougaard Elina Hyppönen Hazel M Inskip Aaron Isaacs Torben Jørgensen Christina Kanaka-Gantenbein John P Kemp Wieland Kiess Tuomas O Kilpeläinen Norman Klopp Bridget A Knight Christopher W Kuzawa George McMahon John P Newnham Harri Niinikoski Ben A Oostra Louise Pedersen Dirkje S Postma Susan M Ring Fernando Rivadeneira Neil R Robertson Sylvain Sebert Olli Simell Torsten Slowinski Carla M T Tiesler Anke Tönjes Allan Vaag Jorma S Viikari Jacqueline M Vink Nadja Hawwa Vissing Nicholas J Wareham Gonneke Willemsen Daniel R Witte Haitao Zhang Jianhua Zhao James F Wilson Michael Stumvoll Andrew M Prentice Brian F Meyer Ewan R Pearson Colin A G Boreham Cyrus Cooper Matthew W Gillman George V Dedoussis Luis A Moreno Oluf Pedersen Maiju Saarinen Karen L Mohlke Dorret I Boomsma Seang-Mei Saw Timo A Lakka Antje Körner Ruth J F Loos Ken K Ong Peter Vollenweider Cornelia M van Duijn Gerard H Koppelman Andrew T Hattersley John W Holloway Berthold Hocher Joachim Heinrich Chris Power Mads Melbye Mònica Guxens Craig E Pennell Klaus Bønnelykke Hans Bisgaard Johan G Eriksson Elisabeth Widén Hakon Hakonarson André G Uitterlinden Anneli Pouta Debbie A Lawlor George Davey Smith Timothy M Frayling Mark I McCarthy Struan F A Grant Vincent W V Jaddoe Marjo-Riitta Jarvelin Nicholas J Timpson Inga Prokopenko Rachel M Freathy

Nat Genet 2013 Jan 2;45(1):76-82. Epub 2012 Dec 2.

Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1038/ng.2477DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3605762PMC
January 2013

Analysis of blood-based gene expression signature in first-episode psychosis.

Psychiatry Res 2012 Nov 13;200(1):52-4. Epub 2012 Apr 13.

Department of General Psychiatry 1 & Research Division, Institute of Mental Health/Woodbridge Hospital, and Office of Clinical Sciences, Duke-National University of Singapore Graduate Medical School, Singapore.

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http://dx.doi.org/10.1016/j.psychres.2012.03.021DOI Listing
November 2012

Large scale international replication and meta-analysis study confirms association of the 15q14 locus with myopia. The CREAM consortium.

Authors:
Virginie J M Verhoeven Pirro G Hysi Seang-Mei Saw Veronique Vitart Alireza Mirshahi Jeremy A Guggenheim Mary Frances Cotch Kenji Yamashiro Paul N Baird David A Mackey Robert Wojciechowski M Kamran Ikram Alex W Hewitt Priya Duggal Sarayut Janmahasatian Chiea-Chuen Khor Qiao Fan Xin Zhou Terri L Young E-Shyong Tai Liang-Kee Goh Yi-Ju Li Tin Aung Eranga Vithana Yik-Ying Teo Wanting Tay Xueling Sim Igor Rudan Caroline Hayward Alan F Wright Ozren Polasek Harry Campbell James F Wilson Brian W Fleck Isao Nakata Nagahisa Yoshimura Ryo Yamada Fumihiko Matsuda Kyoko Ohno-Matsui Abhishek Nag George McMahon Beate St Pourcain Yi Lu Jugnoo S Rahi Phillippa M Cumberland Shomi Bhattacharya Claire L Simpson Larry D Atwood Xiaohui Li Leslie J Raffel Federico Murgia Laura Portas Dominiek D G Despriet Leonieke M E van Koolwijk Christian Wolfram Karl J Lackner Anke Tönjes Reedik Mägi Terho Lehtimäki Mika Kähönen Tõnu Esko Andres Metspalu Taina Rantanen Olavi Pärssinen Barbara E Klein Thomas Meitinger Timothy D Spector Ben A Oostra Albert V Smith Paulus T V M de Jong Albert Hofman Najaf Amin Lennart C Karssen Fernando Rivadeneira Johannes R Vingerling Guðný Eiríksdóttir Vilmundur Gudnason Angela Döring Thomas Bettecken André G Uitterlinden Cathy Williams Tanja Zeller Raphaële Castagné Konrad Oexle Cornelia M van Duijn Sudha K Iyengar Paul Mitchell Jie Jin Wang René Höhn Norbert Pfeiffer Joan E Bailey-Wilson Dwight Stambolian Tien-Yin Wong Christopher J Hammond Caroline C W Klaver

Hum Genet 2012 Sep 5;131(9):1467-80. Epub 2012 Jun 5.

Department of Ophthalmology, Erasmus Medical Center, 3000 CA Rotterdam, The Netherlands.

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http://dx.doi.org/10.1007/s00439-012-1176-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3418496PMC
September 2012

Genetic and bioinformatic analyses of the expression and function of PI3K regulatory subunit PIK3R3 in an Asian patient gastric cancer library.

BMC Med Genomics 2012 Aug 9;5:34. Epub 2012 Aug 9.

Laboratory of Hormonal Regulation, Cardiovascular and Metabolic Disorders Program, Duke-National University of Singapore Graduate Medical School, Singapore.

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http://bmcmedgenomics.biomedcentral.com/articles/10.1186/175
Publisher Site
http://dx.doi.org/10.1186/1755-8794-5-34DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3479415PMC
August 2012

Hepatocyte growth factor and retinal arteriolar diameter in Singapore Chinese.

Ophthalmology 2010 May 1;117(5):939-45. Epub 2010 Feb 1.

Section for Genetic Medicine, Singapore Institute for Clinical Sciences, Agency for Science, Technology and Research, Singapore, Republic of Singapore.

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http://dx.doi.org/10.1016/j.ophtha.2009.09.055DOI Listing
May 2010