Liam R Cox

Liam R Cox

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Liam R Cox

Liam R Cox

Publications by authors named "Liam R Cox"

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Ligand-dependent downregulation of MR1 cell surface expression.

Proc Natl Acad Sci U S A 2020 May 27;117(19):10465-10475. Epub 2020 Apr 27.

MRC Human Immunology Unit, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford OX3 9DS, United Kingdom.

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http://dx.doi.org/10.1073/pnas.2003136117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7229755PMC
May 2020

CD1d-mediated activation of group 3 innate lymphoid cells drives IL-22 production.

EMBO Rep 2017 01 31;18(1):39-47. Epub 2016 Oct 31.

The Peter Gorer Department of Immunobiology, King's College London, London, UK

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http://dx.doi.org/10.15252/embr.201642412DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5210076PMC
January 2017

Non-glycosidic compounds can stimulate both human and mouse iNKT cells.

Eur J Immunol 2016 05 1;46(5):1224-34. Epub 2016 Mar 1.

MRC Human Immunology Unit, Radcliffe Department of Medicine, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1002/eji.201546114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4913735PMC
May 2016

In contrast to other species, α-Galactosylceramide (α-GalCer) is not an immunostimulatory NKT cell agonist in horses.

Dev Comp Immunol 2015 Mar 10;49(1):49-58. Epub 2014 Nov 10.

Department of Veterinary Microbiology and Pathology, Washington State University, College of Veterinary Medicine, P.O. Box 647040, Pullman, WA 99164-7040, USA. Electronic address:

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http://dx.doi.org/10.1016/j.dci.2014.11.005DOI Listing
March 2015

Activation of iNKT cells by a distinct constituent of the endogenous glucosylceramide fraction.

Proc Natl Acad Sci U S A 2014 Sep 2;111(37):13433-8. Epub 2014 Sep 2.

Department of Medicine, Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115;

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http://dx.doi.org/10.1073/pnas.1415357111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4169973PMC
September 2014

Ultrasound-induced emulsification of subcritical carbon dioxide/water with and without surfactant as a strategy for enhanced mass transport.

Ultrason Sonochem 2014 Jan 3;21(1):401-8. Epub 2013 Jun 3.

School of Chemical Engineering, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK.

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http://dx.doi.org/10.1016/j.ultsonch.2013.05.017DOI Listing
January 2014

Saposins modulate human invariant Natural Killer T cells self-reactivity and facilitate lipid exchange with CD1d molecules during antigen presentation.

Proc Natl Acad Sci U S A 2013 Dec 18;110(49):E4753-61. Epub 2013 Nov 18.

Medical Research Council Human Immunology Unit, Radcliffe Department of Medicine, Medical Research Council Weatherall Institute of Molecular Medicine, University of Oxford, Headington, Oxford OX3 9DS, United Kingdom.

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http://dx.doi.org/10.1073/pnas.1310050110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3856826PMC
December 2013

Endoplasmic reticulum glycoprotein quality control regulates CD1d assembly and CD1d-mediated antigen presentation.

J Biol Chem 2013 Jun 24;288(23):16391-402. Epub 2013 Apr 24.

Section of Infectious Diseases, Department of Internal Medicine, Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, Connecticut 06520-8011, USA.

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http://dx.doi.org/10.1074/jbc.M113.474221DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3675576PMC
June 2013

Disruption of the serine/threonine protein kinase H affects phthiocerol dimycocerosates synthesis in Mycobacterium tuberculosis.

Microbiology 2013 Apr 14;159(Pt 4):726-736. Epub 2013 Feb 14.

Department of Medicine, Division of Infectious Diseases, Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada.

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http://mic.microbiologyresearch.org/content/journal/micro/10
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http://dx.doi.org/10.1099/mic.0.062067-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3709824PMC
April 2013

Design, synthesis, and functional activity of labeled CD1d glycolipid agonists.

Bioconjug Chem 2013 Apr 19;24(4):586-94. Epub 2013 Mar 19.

School of Chemistry, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK.

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http://dx.doi.org/10.1021/bc300556eDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3630740PMC
April 2013

Role for lysosomal phospholipase A2 in iNKT cell-mediated CD1d recognition.

Proc Natl Acad Sci U S A 2013 Mar 14;110(13):5097-102. Epub 2013 Mar 14.

Department of Immunobiology, Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, CT 06520-8011, USA.

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http://dx.doi.org/10.1073/pnas.1302923110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3612615PMC
March 2013

Amide analogues of CD1d agonists modulate iNKT-cell-mediated cytokine production.

ACS Chem Biol 2012 May 29;7(5):847-55. Epub 2012 Feb 29.

School of Chemistry, University of Birmingham, Edgbaston, Birmingham B15 2TT, U.K.

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http://dx.doi.org/10.1021/cb2005017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3409616PMC
May 2012

Synthesis of a versatile building block for the preparation of 6-N-derivatized α-galactosyl ceramides: rapid access to biologically active glycolipids.

J Org Chem 2011 Jan 14;76(1):320-3. Epub 2010 Dec 14.

School of Biosciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, United Kingdom.

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http://dx.doi.org/10.1021/jo102064pDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3018865PMC
January 2011

Synthesis of hybrid masked triyne-phenylene axial rods containing (E)-beta-chlorovinylsilanes in the pi-conjugated framework.

J Org Chem 2009 Oct;74(20):7898-907

School of Chemistry, The University of Birmingham, Edgbaston, Birmingham, B15 2TT, United Kingdom.

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http://dx.doi.org/10.1021/jo901766pDOI Listing
October 2009

Total synthesis and proof of relative stereochemistry of (-)-aureonitol.

J Org Chem 2008 Oct 6;73(19):7616-24. Epub 2008 Sep 6.

School of Chemistry, The University of Birmingham, Edgbaston, Birmingham, B15 2TT, United Kingdom.

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http://dx.doi.org/10.1021/jo801338tDOI Listing
October 2008

Temporary silicon connection strategies in intramolecular allylation of aldehydes with allylsilanes.

J Org Chem 2008 Jul 17;73(14):5462-75. Epub 2008 Jun 17.

School of Chemistry, The University of Birmingham, Edgbaston, Birmingham, B15 2TT, United Kingdom.

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http://dx.doi.org/10.1021/jo800824xDOI Listing
July 2008

A Brønsted acid mediated cascade enone synthesis from aldehydes containing a tethered propargylsilane.

J Org Chem 2008 Feb 16;73(4):1631-4. Epub 2008 Jan 16.

School of Chemistry, The University of Birmingham, Edgbaston, Birmingham B15 2TT, UK.

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http://dx.doi.org/10.1021/jo702351sDOI Listing
February 2008

Stereoselective synthesis of 2-dienyl-substituted piperidines using an eta4-dienetricarbonyliron complex as the stereocontrolling element in a double reductive amination cascade.

Org Biomol Chem 2007 Oct 12;5(20):3325-9. Epub 2007 Sep 12.

School of Chemistry, University of Birmingham, Edgbaston, Birmingham, UKB15 2TT.

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http://dx.doi.org/10.1039/b710898bDOI Listing
October 2007

Beta-chlorovinylsilanes as masked alkynes in oligoyne assembly: synthesis of the first aryl-end-capped dodecayne.

Chem Commun (Camb) 2007 Oct 23(39):4035-7. Epub 2007 Aug 23.

School of Chemistry, University of Birmingham, Edgbaston, Birmingham, UK B15 2TT.

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http://dx.doi.org/10.1039/b707681aDOI Listing
October 2007

Tether-directed synthesis of highly substituted oxasilacycles via an intramolecular allylation employing allylsilanes.

Beilstein J Org Chem 2007 Feb 8;3. Epub 2007 Feb 8.

School of Chemistry, The University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK.

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http://dx.doi.org/10.1186/1860-5397-3-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1810303PMC
February 2007

Stereoselective synthesis of 2,4,5-trisubstituted tetrahydropyrans using an intramolecular allylation strategy.

Org Lett 2006 Sep;8(20):4649-52

School of Chemistry, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK.

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http://dx.doi.org/10.1021/ol061957vDOI Listing
September 2006

Regio- and stereoselective hydrosilylation of terminal alkynes using Grubbs' first-generation olefin-metathesis catalyst.

Org Biomol Chem 2004 Sep 13;2(18):2558-62. Epub 2004 Aug 13.

School of Chemistry, The University of Birmingham, Edgbaston, Birmingham, UK B15 2TT.

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http://dx.doi.org/10.1039/B409832CDOI Listing
September 2004

Stereoselective synthesis of allyl-C-mannosyl compounds: use of a temporary silicon connection in intramolecular allylation strategies with allylsilanes.

J Org Chem 2004 Sep;69(19):6341-56

School of Chemistry, The University of Birmingham, Edgbaston, Birmingham B15 2TT, UK.

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http://pubs.acs.org/doi/abs/10.1021/jo049061w
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http://dx.doi.org/10.1021/jo049061wDOI Listing
September 2004

Using a temporary silicon connection in stereoselective allylation with allylsilanes: application to the synthesis of stereodefined 1,2,4-triols.

Org Lett 2003 Oct;5(22):4231-4

School of Chemistry, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK.

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http://dx.doi.org/10.1021/ol035762oDOI Listing
October 2003

Catalytic asymmetric synthesis of a 1-deoxy-1,1-difluoro-D-xylulose.

Org Lett 2003 Feb;5(3):337-9

School of Chemical Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, United Kingdom.

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http://dx.doi.org/10.1021/ol0273553DOI Listing
February 2003

1,3-Diethynylallenes: New Modules for Three-Dimensional Acetylenic Scaffolding.

Angew Chem Int Ed Engl 2001 Jun;40(12):2334-2337

Laboratorium für Organische Chemie, ETH-Zentrum Universitätstrasse 16, 8092 Zürich (Switzerland) Fax: (+41) 1-632-1109.

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http://dx.doi.org/10.1002/1521-3773(20010618)40:12<2334::AID-ANIE2334>3.0.CO;2-7DOI Listing
June 2001

1,3-Diethynylallenes: New Modules for Three-Dimensional Acetylenic Scaffolding We thank the ETH Research Council and the Fonds der Chemischen Industrie for their support of this work.

Angew Chem Int Ed Engl 2001 Jun;40(12):2334-2337

Laboratorium für Organische Chemie, ETH-Zentrum Universitätstrasse 16, 8092 Zürich (Switzerland).

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June 2001

(pi-Allyl)tricarbonyliron Lactone Complexes in Organic Synthesis: A Useful and Conceptually Unusual Route to Lactones and Lactams.

Chem Rev 1996 Feb;96(1):423-442

Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, UK.

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http://dx.doi.org/10.1021/cr950015tDOI Listing
February 1996