Li-Shiun Chen

Li-Shiun Chen

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Li-Shiun Chen

Li-Shiun Chen

Publications by authors named "Li-Shiun Chen"

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Determining population stratification and subgroup effects in association studies of rare genetic variants for nicotine dependence.

Psychiatr Genet 2019 Aug;29(4):111-119

Institute of Biomedical Sciences, Academia Sinica, Nankang, Taipei, Taiwan.

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http://dx.doi.org/10.1097/YPG.0000000000000227DOI Listing
August 2019

Leverage points to improve smoking cessation treatment in a large tertiary care hospital: a systems-based mixed methods study.

BMJ Open 2019 Jul 2;9(7):e030066. Epub 2019 Jul 2.

Department of Psychiatry, Washington University School of Medicine in Saint Louis, Saint Louis, Missouri, USA.

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http://dx.doi.org/10.1136/bmjopen-2019-030066DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6609123PMC
July 2019

Tobacco Genomics: Complexity and Translational Challenges.

Nicotine Tob Res 2019 May;21(6):705-706

Department of Family Medicine, The University of Chicago.

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http://dx.doi.org/10.1093/ntr/ntz033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6528148PMC
May 2019

Variants in the CHRNA5-CHRNA3-CHRNB4 region of chromosome 15 predict gastrointestinal adverse events in the TTURC smoking cessation trial.

Nicotine Tob Res 2019 Mar 18. Epub 2019 Mar 18.

Department of Psychiatry, Washington University School of Medicine, Saint Louis, MO, USA.

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http://dx.doi.org/10.1093/ntr/ntz044DOI Listing
March 2019

Most Current Smokers Desire Genetic Susceptibility Testing and Genetically-Efficacious Medication.

J Neuroimmune Pharmacol 2018 12 29;13(4):430-437. Epub 2018 Oct 29.

Department of Psychiatry, Washington University School of Medicine, 660 S. Euclid Ave., Campus Box 8134, St. Louis, MO, 63110, USA.

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http://dx.doi.org/10.1007/s11481-018-9818-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6245658PMC
December 2018

Use of polygenic risk scores of nicotine metabolism in predicting smoking behaviors.

Pharmacogenomics 2018 12 16;19(18):1383-1394. Epub 2018 Nov 16.

Department of Psychiatry, Washington University School of Medicine, St Louis, MO 63110, USA.

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https://www.futuremedicine.com/doi/10.2217/pgs-2018-0081
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http://dx.doi.org/10.2217/pgs-2018-0081DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562697PMC
December 2018

Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders.

Authors:
Raymond K Walters Renato Polimanti Emma C Johnson Jeanette N McClintick Mark J Adams Amy E Adkins Fazil Aliev Silviu-Alin Bacanu Anthony Batzler Sarah Bertelsen Joanna M Biernacka Tim B Bigdeli Li-Shiun Chen Toni-Kim Clarke Yi-Ling Chou Franziska Degenhardt Anna R Docherty Alexis C Edwards Pierre Fontanillas Jerome C Foo Louis Fox Josef Frank Ina Giegling Scott Gordon Laura M Hack Annette M Hartmann Sarah M Hartz Stefanie Heilmann-Heimbach Stefan Herms Colin Hodgkinson Per Hoffmann Jouke Jan Hottenga Martin A Kennedy Mervi Alanne-Kinnunen Bettina Konte Jari Lahti Marius Lahti-Pulkkinen Dongbing Lai Lannie Ligthart Anu Loukola Brion S Maher Hamdi Mbarek Andrew M McIntosh Matthew B McQueen Jacquelyn L Meyers Yuri Milaneschi Teemu Palviainen John F Pearson Roseann E Peterson Samuli Ripatti Euijung Ryu Nancy L Saccone Jessica E Salvatore Sandra Sanchez-Roige Melanie Schwandt Richard Sherva Fabian Streit Jana Strohmaier Nathaniel Thomas Jen-Chyong Wang Bradley T Webb Robbee Wedow Leah Wetherill Amanda G Wills Jason D Boardman Danfeng Chen Doo-Sup Choi William E Copeland Robert C Culverhouse Norbert Dahmen Louisa Degenhardt Benjamin W Domingue Sarah L Elson Mark A Frye Wolfgang Gäbel Caroline Hayward Marcus Ising Margaret Keyes Falk Kiefer John Kramer Samuel Kuperman Susanne Lucae Michael T Lynskey Wolfgang Maier Karl Mann Satu Männistö Bertram Müller-Myhsok Alison D Murray John I Nurnberger Aarno Palotie Ulrich Preuss Katri Räikkönen Maureen D Reynolds Monika Ridinger Norbert Scherbaum Marc A Schuckit Michael Soyka Jens Treutlein Stephanie Witt Norbert Wodarz Peter Zill Daniel E Adkins Joseph M Boden Dorret I Boomsma Laura J Bierut Sandra A Brown Kathleen K Bucholz Sven Cichon E Jane Costello Harriet de Wit Nancy Diazgranados Danielle M Dick Johan G Eriksson Lindsay A Farrer Tatiana M Foroud Nathan A Gillespie Alison M Goate David Goldman Richard A Grucza Dana B Hancock Kathleen Mullan Harris Andrew C Heath Victor Hesselbrock John K Hewitt Christian J Hopfer John Horwood William Iacono Eric O Johnson Jaakko A Kaprio Victor M Karpyak Kenneth S Kendler Henry R Kranzler Kenneth Krauter Paul Lichtenstein Penelope A Lind Matt McGue James MacKillop Pamela A F Madden Hermine H Maes Patrik Magnusson Nicholas G Martin Sarah E Medland Grant W Montgomery Elliot C Nelson Markus M Nöthen Abraham A Palmer Nancy L Pedersen Brenda W J H Penninx Bernice Porjesz John P Rice Marcella Rietschel Brien P Riley Richard Rose Dan Rujescu Pei-Hong Shen Judy Silberg Michael C Stallings Ralph E Tarter Michael M Vanyukov Scott Vrieze Tamara L Wall John B Whitfield Hongyu Zhao Benjamin M Neale Joel Gelernter Howard J Edenberg Arpana Agrawal

Nat Neurosci 2018 12 26;21(12):1656-1669. Epub 2018 Nov 26.

Washington University School of Medicine, Department of Psychiatry, St. Louis, MO, USA.

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http://dx.doi.org/10.1038/s41593-018-0275-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6430207PMC
December 2018

Finding paths with the greatest chance of success: enabling and focusing lung cancer screening and cessation in resource-constrained areas.

Transl Lung Cancer Res 2018 Sep;7(Suppl 3):S261-S264

Center for Research on Women and Gender, College of Medicine, University of Illinois at Chicago, Chicago, IL 60607, USA.

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http://tlcr.amegroups.com/article/view/24028/18282
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http://dx.doi.org/10.21037/tlcr.2018.09.11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6193916PMC
September 2018

Low-Burden Strategies to Promote Smoking Cessation Treatment Among Patients With Serious Mental Illness.

Psychiatr Serv 2018 08 1;69(8):849-851. Epub 2018 Jun 1.

Dr. Chen, Dr. Brownson, and Dr. Bierut are with the Siteman Cancer Center and Institute of Public Health Sciences, and Dr. Chen and Dr. Bierut are also with the Department of Psychiatry, Washington University School of Medicine in St. Louis, St. Louis. Dr. Brownson is also with the School of Social Work, Washington University in St. Louis. Dr. Baker is with the Center for Tobacco Research and Intervention, Department of Medicine, School of Medicine and Public Health, University of Wisconsin-Madison. Dr. Korpecki, Dr. Johnson, and Dr. Hook are with BJC Behavioral Health, BJC Healthcare, St. Louis. Marcela Horvitz-Lennon, M.D., and Kenneth Minkoff, M.D., are editors of this column.

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http://dx.doi.org/10.1176/appi.ps.201700399DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280191PMC
August 2018

Pathways to precision medicine in smoking cessation treatments.

Neurosci Lett 2018 03 18;669:83-92. Epub 2016 May 18.

Department of Psychiatry, Washington University School of Medicine, St. Louis, MO 63110, United States.

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http://dx.doi.org/10.1016/j.neulet.2016.05.033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5115988PMC
March 2018

Toward the implementation of genomic applications for smoking cessation and smoking-related diseases.

Transl Behav Med 2018 01;8(1):7-17

Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, USA.

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http://dx.doi.org/10.1093/tbm/ibx060DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6065540PMC
January 2018

Smoking Cessation and Electronic Cigarettes in Community Mental Health Centers: Patient and Provider Perspectives.

Community Ment Health J 2017 08 30;53(6):695-702. Epub 2016 Nov 30.

Department of Psychiatry, Washington University School of Medicine, 660 S. Euclid Ave., Box 8134, St. Louis, MO, 63110, USA.

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http://dx.doi.org/10.1007/s10597-016-0065-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5449258PMC
August 2017

Task-related fMRI responses to a nicotinic acetylcholine receptor partial agonist in schizophrenia: A randomized trial.

Prog Neuropsychopharmacol Biol Psychiatry 2016 11 28;71:66-75. Epub 2016 Jun 28.

Novartis Pharma AG, Basel, Switzerland; Department of Neurology and Neurosurgery, McGill University, Montreal, Québec, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.pnpbp.2016.06.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6432789PMC
November 2016

Associations between smoking behavior-related alleles and the risk of melanoma.

Oncotarget 2016 Jul;7(30):47366-47375

Department of Epidemiology, Richard M. Fairbanks School of Public Health, Melvin and Bren Simon Cancer Center, Indiana University, Indianapolis, Indiana, USA.

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http://dx.doi.org/10.18632/oncotarget.10144DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216947PMC
July 2016

Association of the OPRM1 Variant rs1799971 (A118G) with Non-Specific Liability to Substance Dependence in a Collaborative de novo Meta-Analysis of European-Ancestry Cohorts.

Authors:
Tae-Hwi Schwantes-An Juan Zhang Li-Shiun Chen Sarah M Hartz Robert C Culverhouse Xiangning Chen Hilary Coon Josef Frank Helen M Kamens Bettina Konte Leena Kovanen Antti Latvala Lisa N Legrand Brion S Maher Whitney E Melroy Elliot C Nelson Mark W Reid Jason D Robinson Pei-Hong Shen Bao-Zhu Yang Judy A Andrews Paul Aveyard Olga Beltcheva Sandra A Brown Dale S Cannon Sven Cichon Robin P Corley Norbert Dahmen Louisa Degenhardt Tatiana Foroud Wolfgang Gaebel Ina Giegling Stephen J Glatt Richard A Grucza Jill Hardin Annette M Hartmann Andrew C Heath Stefan Herms Colin A Hodgkinson Per Hoffmann Hyman Hops David Huizinga Marcus Ising Eric O Johnson Elaine Johnstone Radka P Kaneva Kenneth S Kendler Falk Kiefer Henry R Kranzler Ken S Krauter Orna Levran Susanne Lucae Michael T Lynskey Wolfgang Maier Karl Mann Nicholas G Martin Manuel Mattheisen Grant W Montgomery Bertram Müller-Myhsok Michael F Murphy Michael C Neale Momchil A Nikolov Denise Nishita Markus M Nöthen John Nurnberger Timo Partonen Michele L Pergadia Maureen Reynolds Monika Ridinger Richard J Rose Noora Rouvinen-Lagerström Norbert Scherbaum Christine Schmäl Michael Soyka Michael C Stallings Michael Steffens Jens Treutlein Ming Tsuang Tamara L Wall Norbert Wodarz Vadim Yuferov Peter Zill Andrew W Bergen Jingchun Chen Paul M Cinciripini Howard J Edenberg Marissa A Ehringer Robert E Ferrell Joel Gelernter David Goldman John K Hewitt Christian J Hopfer William G Iacono Jaakko Kaprio Mary Jeanne Kreek Ivo M Kremensky Pamela A F Madden Matt McGue Marcus R Munafò Robert A Philibert Marcella Rietschel Alec Roy Dan Rujescu Sirkku T Saarikoski Gary E Swan Alexandre A Todorov Michael M Vanyukov Robert B Weiss Laura J Bierut Nancy L Saccone

Behav Genet 2016 Mar 21;46(2):151-69. Epub 2015 Sep 21.

Department of Genetics, Washington University School of Medicine, 4523 Clayton Avenue, Campus Box 8232, St. Louis, MO, 63110, USA.

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https://genepi.qimr.edu.au/contents/p/staff/Schwantes_An_Beh
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http://link.springer.com/10.1007/s10519-015-9737-3
Publisher Site
http://dx.doi.org/10.1007/s10519-015-9737-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4752855PMC
March 2016

The value of control conditions for evaluating pharmacogenetic effects.

Pharmacogenomics 2015 Dec 26;16(18):2005-6. Epub 2015 Nov 26.

Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA.

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http://dx.doi.org/10.2217/pgs.15.143DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5558525PMC
December 2015

Genetic variation (CHRNA5), medication (combination nicotine replacement therapy vs. varenicline), and smoking cessation.

Drug Alcohol Depend 2015 Sep 23;154:278-82. Epub 2015 Jun 23.

Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, 63110, United States; The Alvin J. Siteman Cancer Center, Washington University School of Medicine, St. Louis, MO, 63110, United States.

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http://dx.doi.org/10.1016/j.drugalcdep.2015.06.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4537319PMC
September 2015

CHRNA5 risk variant predicts delayed smoking cessation and earlier lung cancer diagnosis--a meta-analysis.

J Natl Cancer Inst 2015 May 14;107(5). Epub 2015 Apr 14.

Department of Psychiatry, Washington University School of Medicine, St. Louis, MO (LSC, AHo, LJB); The Alvin J. Siteman Cancer Center, Washington University School of Medicine, St. Louis, MO (LSC, LJB); Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, Canada (RJH, JM); Tobacco Research and Intervention, University of Wisconsin, School of Medicine, Madison, WI (TB); Department of Medicine, Washington University School of Medicine, St. Louis, MO (RC); Department of Genetics, Washington University School of Medicine, St. Louis, MO (NS); Cancer Prevention Institute of California, Fremont, CA (IC); Division of Epidemiology, Department of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, MN (BD, JW, PY); Department of Community and Family Medicine, Geisel School of Medicine at Dartmouth, Hanover, NH (YH, CIA); Department of Neurological Surgery, University of California San Francisco, San Francisco, CA (HMH, MRW, JKW); Department of Oncology, University of Sheffield, Sheffield, UK (JHo, PW); Department of Epidemiology, UCLA Fielding School of Public Health, University of California Los Angeles, Los Angeles, CA (CK, ZFZ); Department of Biostatistics & Informatics, University of Colorado Anschutz Medical Campus, Denver, CO (SL); Department of Genetic Epidemiology, University of Goettingen Medical School, Goettingen, Germany (AR, HBi); Comprehensive Cancer Centre, the Netherlands, Utrecht, Netherland & Department for Health Evidence, Radboud University Medical Center, Nijmegen, the Netherlands (KKA); Norris Cotton Cancer Center, Geisel School of Medicine at Dartmouth, Lebanon, NH (ASA); Department of Epidemiology, Michigan State University, East Lansing, MI (NB); Division of Clinical Epidemiology and Aging Research German Cancer Research Center, German Cancer research Center, Heidelberg, Germany (AKD, HBr); German Cancer Consortium, Heidelberg, Germany (AKD, HBr); Department of Thoracic Surgery, Thoraxklinik at University Hospital

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http://dx.doi.org/10.1093/jnci/djv100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4822525PMC
May 2015

Interplay of genetic risk (CHRNA5) and environmental risk (partner smoking) on cigarette smoking reduction.

Drug Alcohol Depend 2014 Oct 3;143:36-43. Epub 2014 Jul 3.

Department of Psychiatry, Washington University School of Medicine, St. Louis, MO 63110, United States.

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http://dx.doi.org/10.1016/j.drugalcdep.2014.06.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161618PMC
October 2014

CHRNA5 variant predicts smoking cessation in patients with acute myocardial infarction.

Nicotine Tob Res 2014 Sep 11;16(9):1224-31. Epub 2014 Apr 11.

Department of Medicine, Washington University School of Medicine, St. Louis, MO; Department of Genetics, Washington University School of Medicine, St. Louis, MO;

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http://dx.doi.org/10.1093/ntr/ntu059DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4155476PMC
September 2014

Pharmacotherapy effects on smoking cessation vary with nicotine metabolism gene (CYP2A6).

Addiction 2014 Jan 11;109(1):128-137. Epub 2013 Nov 11.

Department of Psychiatry, Washington University School of Medicine, St. Louis, MO 63110.

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http://dx.doi.org/10.1111/add.12353DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3946972PMC
January 2014

Genomics and personalized medicine: and smoking cessation treatment.

J Food Drug Anal 2013 Dec;21(4):S87-S90

Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA.

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http://dx.doi.org/10.1016/j.jfda.2013.09.041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4158847PMC
December 2013

Genetics and pharmacogenetics of substance use disorders.

J Food Drug Anal 2013 Dec;21(4):S23-S24

Center for Neuropsychiatric Research, National Health Research Institutes, Taiwan, Republic of China.

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http://dx.doi.org/10.1016/j.jfda.2013.09.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176940PMC
December 2013

Dissection of the phenotypic and genotypic associations with nicotinic dependence.

Nicotine Tob Res 2012 Apr 18;14(4):425-33. Epub 2011 Nov 18.

Department of Psychiatry (Box 8134), Washington University School of Medicine, 660S. Euclid Ave., St. Louis, MO 63110, USA.

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https://academic.oup.com/ntr/article-lookup/doi/10.1093/ntr/
Publisher Site
http://dx.doi.org/10.1093/ntr/ntr231DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3313785PMC
April 2012

Peer smoking and the nicotinic receptor genes: an examination of genetic and environmental risks for nicotine dependence.

Addiction 2010 Nov 15;105(11):2014-22. Epub 2010 Sep 15.

Behavioral Health Epidemiology Program, Research Triangle Institute International, 3040 Cornwallis Road, Research Triangle Park, NC 27709-2194, USA.

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http://dx.doi.org/10.1111/j.1360-0443.2010.03074.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2970633PMC
November 2010

Familial aggregation of clinical and neurocognitive features in sibling pairs with and without schizophrenia.

Schizophr Res 2009 Jun 23;111(1-3):159-66. Epub 2009 Apr 23.

Department of Psychiatry, Washington University School of Medicine, St. Louis, MO 63110, USA.

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http://dx.doi.org/10.1016/j.schres.2009.03.030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2813565PMC
June 2009

Agoraphobia in adults: incidence and longitudinal relationship with panic.

Br J Psychiatry 2006 May;188:432-8

Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, 600 North Wolfe Street, Meyer 101, Baltimore, MD 21287, USA.

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http://dx.doi.org/10.1192/bjp.bp.105.010827DOI Listing
May 2006

Incidence rates for alcohol dependence among adults: prospective data from the Baltimore Epidemiologic Catchment Area Follow-Up Survey, 1981-1996.

J Stud Alcohol 2005 Nov;66(6):795-805

The Johns Hopkins Medical Institutions, Welch Center for Prevention, Epidemiology and Clinical Research, 2024 East Monument Street, Suite 2-500, Baltimore, Maryland 21205, USA.

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http://dx.doi.org/10.15288/jsa.2005.66.795DOI Listing
November 2005