Li-Rong Wen

Li-Rong Wen

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Li-Rong Wen

Li-Rong Wen

Publications by authors named "Li-Rong Wen"

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N-Phenoxyamides as Multitasking Reagents: Base-Controlled Selective Construction of Benzofurans or Dihydrobenzofuro[2,3- d]oxazoles.

J Org Chem 2019 Jul 24;84(13):8523-8530. Epub 2019 Jun 24.

State Key Laboratory Base of Eco-Chemical Engineering, College of Chemistry and Molecular Engineering , Qingdao University of Science & Technology , Qingdao 266042 , China.

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http://dx.doi.org/10.1021/acs.joc.9b00858DOI Listing
July 2019

One Base for Two Shots: Metal-Free Substituent-Controlled Synthesis of Two Kinds of Oxadiazine Derivatives from Alkynylbenziodoxolones and Amidoximes.

J Org Chem 2019 Jun 23;84(11):6904-6915. Epub 2019 May 23.

State Key Laboratory Base of Eco-Chemical Engineering, College of Chemistry and Molecular Engineering , Qingdao University of Science and Technology , Qingdao 266042 , P. R. China.

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http://dx.doi.org/10.1021/acs.joc.9b00659DOI Listing
June 2019

Construction of Benzofuran-3(2 H)-one Scaffolds with a Quaternary Center via Rh/Co Relay Catalyzed C-H Functionalization/Annulation of N-Aryloxyacetamides and Propiolic Acids.

Org Lett 2019 03 1;21(6):1654-1658. Epub 2019 Mar 1.

State Key Laboratory Base of Eco-Chemical Engineering, College of Chemistry and Molecular Engineering , Qingdao University of Science and Technology , Qingdao 266042 , P.R. China.

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http://dx.doi.org/10.1021/acs.orglett.9b00181DOI Listing
March 2019

Intramolecular dehydrogenative C-S bond coupling of thioamides to form 1,3-benzothiazines under metal-free conditions.

Org Biomol Chem 2019 Mar;17(13):3356-3360

State Key Laboratory Base of Eco-Chemical Engineering, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, P. R. China.

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http://dx.doi.org/10.1039/c9ob00237eDOI Listing
March 2019

Metal-Free Direct Construction of 2-(Oxazol-5-yl)phenols from N-Phenoxyamides and Alkynylbenziodoxolones via Sequential [3,3]-Rearrangement/Cyclization.

Org Lett 2018 12 29;20(23):7694-7698. Epub 2018 Nov 29.

State Key Laboratory Base of Eco-Chemical Engineering, College of Chemistry and Molecular Engineering , Qingdao University of Science & Technology , Qingdao , 266042 , China.

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http://dx.doi.org/10.1021/acs.orglett.8b03427DOI Listing
December 2018

Nickle Catalysis Enables Access to Thiazolidines from Thioureas via Oxidative Double Isocyanide Insertion Reactions.

Org Lett 2018 11 6;20(22):7158-7162. Epub 2018 Nov 6.

State Key Laboratory Base of Eco-Chemical Engineering, College of Chemistry and Molecular Engineering , Qingdao University of Science and Technology , Qingdao 266042 , P. R. China.

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http://pubs.acs.org/doi/10.1021/acs.orglett.8b03098
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http://dx.doi.org/10.1021/acs.orglett.8b03098DOI Listing
November 2018

Fast Construction of 1,3-Benzothiazepines by Direct Intramolecular Dehydrogenative C-S Bond Formation of Thioamides under Metal-Free Conditions.

Org Lett 2018 10 4;20(20):6394-6397. Epub 2018 Oct 4.

State Key Laboratory Base of Eco-Chemical Engineering, College of Chemistry and Molecular Engineering , Qingdao University of Science & Technology , Qingdao 266042 , China.

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http://pubs.acs.org/doi/10.1021/acs.orglett.8b02697
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http://dx.doi.org/10.1021/acs.orglett.8b02697DOI Listing
October 2018

When Ethyl Isocyanoacetate Meets Isatins: A 1,3-Dipolar/Inverse 1,3-Dipolar/Olefination Reaction for Access to 3-Ylideneoxindoles.

Org Lett 2018 03 8;20(6):1513-1516. Epub 2018 Mar 8.

State Key Laboratory Base of Eco-Chemical Engineering, College of Chemistry and Molecular Engineering , Qingdao University of Science & Technology , Qingdao 266042 , China.

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http://dx.doi.org/10.1021/acs.orglett.8b00217DOI Listing
March 2018

PM Exposure Elicits Oxidative Stress Responses and Mitochondrial Apoptosis Pathway Activation in HaCaT Keratinocytes.

Chin Med J (Engl) 2017 Sep;130(18):2205-2214

Skin Research Center, Landproof Testing Technology Co., Ltd., Guangzhou, Guangdong 510635, China.

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http://www.cmj.org/text.asp?2017/130/18/2205/212942
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http://dx.doi.org/10.4103/0366-6999.212942DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5598333PMC
September 2017

Synthesis of 6-Phosphorylated Phenanthridines by Mn(II)-Promoted Tandem Reactions of 2-Biaryl Isothiocyanates with Phosphine Oxides.

J Org Chem 2017 07 21;82(13):7015-7022. Epub 2017 Jun 21.

State Key Laboratory Base of Eco-Chemical Engineering, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology , Qingdao 266042, China.

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http://dx.doi.org/10.1021/acs.joc.7b00907DOI Listing
July 2017

Synthesis of disulfides tethered pyrroles from β-ketothioamides via a bicyclization/ring-opening/oxidative coupling reaction.

Org Biomol Chem 2017 Jul 29;15(27):5820-5823. Epub 2017 Jun 29.

State Key Laboratory Base of Eco-Chemical Engineering, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, P. R. China.

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http://xlink.rsc.org/?DOI=C7OB00655A
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http://dx.doi.org/10.1039/c7ob00655aDOI Listing
July 2017

Chemo-, Regio-, and Stereoselective Construction of Core Skeleton of Furo[2,3-b]pyrrole via Multicomponent Bicyclization Reaction.

J Org Chem 2017 06 12;82(11):5566-5573. Epub 2017 May 12.

State Key Laboratory Base of Eco-Chemical Engineering, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology , Qingdao 266042, P.R. China.

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http://dx.doi.org/10.1021/acs.joc.7b00371DOI Listing
June 2017

Synthesis of 1-Thio-Substituted Isoquinoline Derivatives by Tandem Cyclization of Isothiocyanates.

J Org Chem 2017 02 23;82(3):1428-1436. Epub 2017 Jan 23.

State Key Laboratory Base of Eco-Chemical Engineering, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology , Qingdao 266042, P. R. China.

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http://dx.doi.org/10.1021/acs.joc.6b02605DOI Listing
February 2017

Direct Construction of 2-Aryliminochromenes from Arynes, N,S-Keteneacetals, and DMF.

J Org Chem 2016 07 28;81(14):5942-8. Epub 2016 Jun 28.

State Key Laboratory Base of Eco-Chemical Engineering, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology , Qingdao 266042, P. R. China.

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http://dx.doi.org/10.1021/acs.joc.6b00843DOI Listing
July 2016

Yb(OTf)3-Mediated Access to Furans from β-Ketothioamides via Eschenmoser Sulfide Contraction Reaction.

J Org Chem 2015 Dec 18;80(24):11999-2005. Epub 2015 Nov 18.

State Key Laboratory Base of Eco-Chemical Engineering, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology , Qingdao 266042, P. R. China.

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http://dx.doi.org/10.1021/acs.joc.5b01924DOI Listing
December 2015

Dual Roles of β-Oxodithioesters in the Copper-Catalyzed Synthesis of Benzo[e]pyrazolo[1,5-c][1,3]thiazine Derivatives.

J Org Chem 2015 May 30;80(10):4942-9. Epub 2015 Apr 30.

State Key Laboratory Base of Eco-Chemical Engineering, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, China.

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http://dx.doi.org/10.1021/acs.joc.5b00288DOI Listing
May 2015

β-ketothioamides: efficient reagents in the synthesis of heterocycles.

Org Biomol Chem 2015 Feb;13(7):1942-53

State Key Laboratory Base of Eco-Chemical Engineering, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, P. R. China.

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http://dx.doi.org/10.1039/c4ob02024cDOI Listing
February 2015

Copper-Catalyzed Tandem Reactions for Synthesis of Pyrazolo[5,1-a]isoquinolines with Heterocyclic Ketene Aminals as Ligands.

J Org Chem 2015 Jan 10;80(1):90-8. Epub 2014 Dec 10.

State Key Laboratory Base of Eco-Chemical Engineering, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, People's Republic of China.

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http://dx.doi.org/10.1021/jo5020323DOI Listing
January 2015

DABCO-mediated isocyanide-based multicomponent reaction: synthesis of highly substituted cyclopentenes.

Org Biomol Chem 2014 Jul;12(26):4628-32

State Key Laboratory Base of Eco-Chemical Engineering, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, P. R. China.

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http://dx.doi.org/10.1039/c4ob00012aDOI Listing
July 2014

Switching regioselectivity of β-ketothioamides by means of iodine catalysis: synthesis of thiazolylidenes and 1,4-dithiines.

Chemistry 2014 Apr 18;20(17):5028-33. Epub 2014 Mar 18.

State Key Laboratory Base of Eco-Chemical Engineering, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042 (P.R. China).

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http://dx.doi.org/10.1002/chem.201304497DOI Listing
April 2014

Three-component cascade annulation of β-ketothioamides promoted by CF3CH2OH: a regioselective synthesis of tetrasubstituted thiophenes.

J Org Chem 2013 Nov 16;78(21):10617-28. Epub 2013 Oct 16.

State Key Laboratory Base of Eco-Chemical Engineering, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology , Qingdao 266042, P. R. China.

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http://dx.doi.org/10.1021/jo401397dDOI Listing
November 2013

(E)-6-(4-Chloro-phen-yl)-4-[(2-cyano-3-phenyl-all-yl)sulfan-yl]-2,2-difluoro-3-phenyl-1,3,2-oxaza-borinin-3-ium-2-uide.

Acta Crystallogr Sect E Struct Rep Online 2013 May 5;69(Pt 5):o648. Epub 2013 Apr 5.

College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, People's Republic of China.

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http://dx.doi.org/10.1107/S1600536813007800DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3647846PMC
May 2013

Direct solvent-free regioselective construction of pyrrolo[1,2-a][1,10]phenanthrolines based on isocyanide-based multicomponent reactions.

Org Lett 2013 Mar 5;15(6):1262-5. Epub 2013 Mar 5.

State Key Laboratory Base of Eco-Chemical Engineering, College of Chemistry, Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, P. R. China.

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http://dx.doi.org/10.1021/ol400191bDOI Listing
March 2013

A new rapid multicomponent domino heteroannulation of heterocyclic ketene aminals: solvent-free regioselective synthesis of functionalized benzo[g]imidazo[1,2-a]quinolinediones.

Org Biomol Chem 2013 Feb 7;11(5):781-6. Epub 2012 Dec 7.

State Key Laboratory Base of Eco-Chemical Engineering, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, PR China.

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http://dx.doi.org/10.1039/c2ob27137kDOI Listing
February 2013

Four-component cascade heteroannulation of heterocyclic ketene aminals: synthesis of functionalized tetrahydroimidazo[1,2-a]pyridine derivatives.

J Org Chem 2012 Oct 26;77(20):8956-67. Epub 2012 Sep 26.

State Key Laboratory Base of Eco-Chemical Engineering, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, People's Republic of China.

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http://dx.doi.org/10.1021/jo3013836DOI Listing
October 2012

One-pot multicomponent cascade reaction of N,S-ketene acetal: solvent-free synthesis of imidazo[1,2-a]thiochromeno[3,2-e]pyridines.

Org Lett 2012 Jul 26;14(13):3470-3. Epub 2012 Jun 26.

State Key Laboratory Base of Eco-Chemical Engineering, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, P. R. China.

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http://dx.doi.org/10.1021/ol301441vDOI Listing
July 2012

Alterations in gene expression and steroidogenesis in the testes of transient cerebral ischemia in male rats.

Chin Med J (Engl) 2012 Jun;125(12):2168-72

Heilongjiang Key Laboratory of Anti-fibrosis Biotherapy, Mudanjiang Medical University, Mudanjiang, Heilongjiang 157001, China.

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June 2012

[Study on HPLC fingerprint of Oldenlandia diffusa].

Zhong Yao Cai 2012 Jun;35(6):886-92

Institute of Traditional Chinese Medicine and Natural Products, College of Pharmacy, Jinan University, Guangzhou 510632, China.

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June 2012

Modulating the reactivity of functionalized N,S-ketene acetal in MCR: selective synthesis of tetrahydropyridines and thiochromeno[2,3-b]pyridines via DABCO-catalyzed tandem annulation.

J Org Chem 2012 May 25;77(9):4252-60. Epub 2012 Apr 25.

State Key Laboratory Base of Eco-Chemical Engineering, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, 53 Zhengzhou Road, Qingdao 266042, P. R. China.

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http://dx.doi.org/10.1021/jo202665qDOI Listing
May 2012

Chemistry of heterocyclic ketene aminals: construction of imidazo(pyrido)[1,2-a]pyridines and imidazo(pyrido)[3,2,1-ij][1,8]naphthyridines via DABCO-catalyzed tandem annulations.

J Org Chem 2011 May 14;76(9):3054-63. Epub 2011 Apr 14.

State Key Laboratory Base of Eco-Chemical Engineering, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, PR China.

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http://dx.doi.org/10.1021/jo102167gDOI Listing
May 2011

Reactivity of functionalized N,S-ketene acetal: regioselective construction of tetrahydrobenzo[b]pyran and chromeno[2,3-b]quinoline derivatives.

J Org Chem 2010 Dec 18;75(24):8522-32. Epub 2010 Nov 18.

State Key Laboratory Base of Eco-Chemical Engineering, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, 53 Zhengzhou Road, Qingdao 266042, PR China.

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http://dx.doi.org/10.1021/jo101902zDOI Listing
December 2010

Modulating the reactivity of heterocyclic ketene aminals in MCR: selective construction of tetrahydrobenzo[b]imidazo[3,2,1-ij][1,8]naphthyridines.

J Org Chem 2010 Nov 27;75(22):7605-14. Epub 2010 Oct 27.

State Key Laboratory Base of Eco-Chemical Engineering, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, P. R. China.

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http://dx.doi.org/10.1021/jo101454qDOI Listing
November 2010

[Studies on technology optimization for extraction and purification of total flavones from root bark of Artocarpus styracifolius].

Zhong Yao Cai 2010 Aug;33(8):1320-3

Key Laboratory of Modern Preparation of TCM, Jiangxi University of Traditional Chinese Medicine, Ministry of Education, Nanchang 330004, China.

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August 2010

7-(2,4-Dichloro-phen-yl)-2-methyl-sulfanyl-pyrazolo[1,5-a]pyrimidine-3-carbonitrile.

Acta Crystallogr Sect E Struct Rep Online 2009 Apr 25;65(Pt 5):o1116. Epub 2009 Apr 25.

College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, People's Republic of China.

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http://dx.doi.org/10.1107/S1600536809014792DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2977792PMC
April 2009

Gephyrin interacts with the glutamate receptor interacting protein 1 isoforms at GABAergic synapses.

J Neurochem 2008 Jun;105(6):2300-14

Department of Physiology and Neurobiology, University of Connecticut, Storrs, Connecticut 06269-3156, USA.

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http://dx.doi.org/10.1111/j.1471-4159.2008.05311.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2891215PMC
June 2008

7-Chloro-4-(2,5-dichloro-phen-yl)-1-phenyl-1H-thio-chromeno[2,3-b]pyridine-2,5(3H,4H)-dione.

Acta Crystallogr Sect E Struct Rep Online 2008 Mar 5;64(Pt 4):o670. Epub 2008 Mar 5.

College of Chemistry and Molecular Engineering, Qingdao University of, Science and Technology, Qingdao 266042, People's Republic of China.

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http://dx.doi.org/10.1107/S1600536808000573DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2960985PMC
March 2008

Application of beta-(2-chloroaroyl) thioacetanilides in synthesis: an unusual and highly efficient access to thiochromeno[2,3-b]pyridine derivatives.

J Org Chem 2008 Mar 26;73(5):1852-63. Epub 2008 Jan 26.

Key Laboratory of Eco-Chemical Engineering, Ministry of Education, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, China.

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http://dx.doi.org/10.1021/jo7024702DOI Listing
March 2008

2-Anilino-3-benzoyl-4-(2,5-dichloro-phen-yl)-7,7-dimethyl-5-oxo-5,6,7,8-tetra-hydro-4H-benzo[b]pyran.

Acta Crystallogr Sect E Struct Rep Online 2008 Jan 9;64(Pt 2):o407. Epub 2008 Jan 9.

College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, People's Republic of China.

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http://dx.doi.org/10.1107/S1600536807068377DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2960223PMC
January 2008

Gephyrin clustering is required for the stability of GABAergic synapses.

Mol Cell Neurosci 2007 Dec 23;36(4):484-500. Epub 2007 Aug 23.

Department of Physiology and Neurobiology, University of Connecticut, Storrs, CT 06269, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S104474310700193
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http://dx.doi.org/10.1016/j.mcn.2007.08.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2464357PMC
December 2007

Disruption of postsynaptic GABA receptor clusters leads to decreased GABAergic innervation of pyramidal neurons.

J Neurochem 2005 Nov;95(3):756-70

Department of Physiology and Neurobiology, University of Connecticut, Storrs, Connecticut 06269, USA.

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http://dx.doi.org/10.1111/j.1471-4159.2005.03426.xDOI Listing
November 2005

GRIP1 in GABAergic synapses.

J Comp Neurol 2005 Jul;488(1):11-27

Department of Physiology and Neurobiology, University of Connecticut at Storrs, 06269, USA.

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http://dx.doi.org/10.1002/cne.20566DOI Listing
July 2005

[Development of morphology and mechanical properties in polyurethane-urea(PUU) curing process].

Guang Pu Xue Yu Guang Pu Fen Xi 2002 Oct;22(5):774-8

Department of Applied Chemistry, Qingdao Institute of Chemical Technology, Qingdao 102200, China.

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October 2002

Synaptic and extrasynaptic GABAA receptor and gephyrin clusters.

Prog Brain Res 2002 ;136:157-80

Department of Physiology and Neurobiology, 3107 Horsebarn Hill Road, U-4156, Storrs, CT 06269, USA.

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http://dx.doi.org/10.1016/s0079-6123(02)36015-1DOI Listing
September 2002