Li-ming Gan

Li-ming Gan

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Li-ming Gan

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Inhibiting myeloperoxidase prevents onset and reverses established high fat diet -induced microvascular insulin resistance.

Am J Physiol Endocrinol Metab 2019 Oct 8. Epub 2019 Oct 8.

Division of Endocrinology, Department of Medicine, Department of Pharmacology , University of Virginia, School of Medicine, Charlottesville, VA 22908; Department of Molecular and Clinical Medicine (L.-M.G.), Institute of Medicine, Sahlgrenska Academy at the University of Gothenburg, SE-413 45 Gothenburg, Sweden; and Cardiovascular, Renal and Metabolism, IMED Biotech Unit (L.-M.G., E.M.), AstraZeneca, Gothenburg, Sweden.

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http://dx.doi.org/10.1152/ajpendo.00203.2019DOI Listing
October 2019

Cardiac expression of the microsomal triglyceride transport protein protects the heart function during ischemia.

J Mol Cell Cardiol 2019 Sep 15;137:1-8. Epub 2019 Sep 15.

Department of Molecular and Clinical Medicine, Wallenberg Laboratory, University of Gothenburg, Sahlgrenska University Hospital, Gothenburg, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.yjmcc.2019.09.003DOI Listing
September 2019

Stimulation of alpha 7 nicotinic acetylcholine receptor (α7nAChR) inhibits atherosclerosis via immunomodulatory effects on myeloid cells.

Atherosclerosis 2019 Aug 15;287:122-133. Epub 2019 Jun 15.

Department of Physiology, Institute of Neuroscience and Physiology, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.atherosclerosis.2019.06.903DOI Listing
August 2019

Frequency of Coronary Microvascular Dysfunction and Diffuse Myocardial Fibrosis (Measured by Cardiovascular Magnetic Resonance) in Patients With Heart Failure and Preserved Left Ventricular Ejection Fraction.

Am J Cardiol 2019 Aug 22. Epub 2019 Aug 22.

Department of Medicine, Cardiovascular Medicine Division, University of Virginia Health System, Charlottesville, Virginia; Department of Biomedical Engineering, University of Virginia Health System, Charlottesville, Virginia; Department of Radiology and Medical Imaging, University of Virginia Health System, Charlottesville, Virginia. Electronic address:

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http://dx.doi.org/10.1016/j.amjcard.2019.08.011DOI Listing
August 2019

Contribution of Gene Regulatory Networks to Heritability of Coronary Artery Disease.

J Am Coll Cardiol 2019 Jun;73(23):2946-2957

Deutsches Herzzentrum München, Klinik für Herz- und Kreislauferkrankungen, Technische Universität München, DZHK (German Centre for Cardiovascular Research), Munich Heart Alliance, Munich, Germany; Integrated Cardio Metabolic Centre, Department of Medicine, Karolinska Institutet, Karolinska Universitetssjukhuset, Huddinge, Sweden; Department of Genetics & Genomic Sciences, Institute of Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, New York; Clinical Gene Networks AB, Stockholm, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.jacc.2019.03.520DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6590059PMC
June 2019

Effects of pretreatment with cardiostimulants and beta-blockers on isoprenaline-induced takotsubo-like cardiac dysfunction in rats.

Int J Cardiol 2019 Apr 21;281:99-104. Epub 2018 Dec 21.

Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Sweden; Department of Anesthesiology and Intensive Care Medicine, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Sweden.

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http://dx.doi.org/10.1016/j.ijcard.2018.12.045DOI Listing
April 2019

SGLT2 inhibition with empagliflozin improves coronary microvascular function and cardiac contractility in prediabetic ob/ob mice.

Cardiovasc Diabetol 2019 02 7;18(1):16. Epub 2019 Feb 7.

Bioscience, Cardiovascular, Renal and Metabolic Diseases, IMED Biotech Unit, AstraZeneca Gothenburg, Pepparedsleden 1, Mölndal, 431 83, Gothenburg, Sweden.

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http://dx.doi.org/10.1186/s12933-019-0820-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366096PMC
February 2019

Effect of renal denervation on coronary flow reserve in patients with resistant hypertension.

Clin Physiol Funct Imaging 2019 Jan 14;39(1):15-21. Epub 2018 May 14.

Department of Clinical Physiology, Sahlgrenska Academy at Gothenburg University, Gothenburg, Sweden.

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http://dx.doi.org/10.1111/cpf.12523DOI Listing
January 2019

PanglaoDB: a web server for exploration of mouse and human single-cell RNA sequencing data.

Database (Oxford) 2019 01;2019

Integrated Cardio Metabolic Centre (ICMC), Department of Medicine, Karolinska Institutet, Novum SE Huddinge, Sweden.

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https://academic.oup.com/database/article/doi/10.1093/databa
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http://dx.doi.org/10.1093/database/baz046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450036PMC
January 2019

Randomized clinical trial studying effects of a personalized supervised lifestyle intervention program on cardiovascular status in physically inactive healthy volunteers.

Oncotarget 2018 Feb 3;9(10):9498-9511. Epub 2018 Jan 3.

Department of Molecular and Clinical Medicine, Institute of Medicine at Sahlgrenska Academy, University of Gothenburg and Sahlgrenska University Hospital, Gothenburg, Sweden.

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http://dx.doi.org/10.18632/oncotarget.23958DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823634PMC
February 2018

Determinants of coronary flow reserve in non-diabetic patients with chest pain without myocardial perfusion defects.

PLoS One 2017 27;12(4):e0176511. Epub 2017 Apr 27.

Department of Molecular and Clinical Medicine, Institute of Medicine at Sahlgrenska Academy, University of Gothenburg and Sahlgrenska University Hospital, Gothenburg, Sweden.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0176511PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5407821PMC
September 2017

Soluble epoxide hydrolase activation by S-nitrosation contributes to cardiac ischemia-reperfusion injury.

J Mol Cell Cardiol 2017 09 20;110:70-79. Epub 2017 Jul 20.

Department of Physiology and Pathophysiology, Peking University Health Science Center, Beijing 100191, China; Tianjin Key Laboratory of Metabolic Diseases, Collaborative Innovation Center of Tianjin for Medical Epigenetics, Department of Physiology and Pathophysiology, Tianjin Medical University, Tianjin 300070, China. Electronic address:

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http://dx.doi.org/10.1016/j.yjmcc.2017.07.006DOI Listing
September 2017

Reassessing Phase II Heart Failure Clinical Trials: Consensus Recommendations.

Circ Heart Fail 2017 Apr;10(4)

From the Department of Medicine, Stony Brook University, NY (J.B., C.E.H.); Division of Cardiology and the CardioVascular Center, Tufts Medical Center, Boston, MA (J.E.U.); Division of Cardiology, Inova Heart & Vascular Institute, Falls Church, VA (C.O'C.); Department of Medicine, Division of Cardiovascular Medicine, Henry Ford Hospital, Detroit, MI (H.N.S.); Division of Cardiology, University of Brescia and Civil Hospital, Italy (M.M.); Division of Cardiology, Northwestern University Feinberg School of Medicine, Chicago, IL (S.J.S., C.Y.); Section on Cardiovascular Medicine, Wake Forest School of Medicine, Winston-Salem, NC (D.W.K.); Division of Cardiology, University of California San Francisco (J.R.T.); Merck & Co., Kenilworth, NJ (H.S.B., J.K.); Gilead Sciences, Foster City, CA (G.B., J.H., C.S.); Amgen Inc., Thousand Oaks, CA (C.D., M.K.); Bristol-Myers Squibb, Princeton, NJ (M.M.D., M.D., R.J.F., P.M., S.M., C.R.); Bayer, Wuppertal, Germany (W.D., M.v.d.L.); Department of Cardiology, HELIOS Clinic Wuppertal, University Hospital Witten/Herdecke, Germany (W.D.); AstraZeneca, Gaithersburg, MD (R.F.-D., J.H., L.-M.G.); AstraZeneca, Gothenburg, Sweden (R.F.-D., J.H., L.-M.G.); Relypsa Inc., Redwood City, CA (D.G., M.M.); Vifor Pharma, Opfikon, Switzerland (U.-M.G.); Department of Cardiology, Nippon Medical School Musashi-Kosugi Hospital, Kawasaki, Japan (S.I.); Novartis Pharmaceuticals Inc., East Hanover, NJ (P.K.-M., V.S.); Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA (C.J.L.); Bayer Pharma AG, Wuppertal, Germany (L.R.); Cardiology Division, Columbia University Medical Center, New York, NY (C.R.); Boehringer Ingelheim Pharmaceuticals Inc, Ridgefield, CT (A.S.); Moderna Therapeutics, Cambridge, MA (B.T.); Division of Cardiovascular and Renal Products, United States Food and Drug Administration, Silver Spring, MD (N.S.); Center for Cardiovascular Innovation, Feinberg School of Medicine, Northwestern University, Chicago, IL (M.G.).

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http://dx.doi.org/10.1161/CIRCHEARTFAILURE.116.003800DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5400283PMC
April 2017

Coronary flow reserve in patients with resistant hypertension.

Clin Res Cardiol 2017 Feb 17;106(2):151-157. Epub 2016 Oct 17.

Department of Cardiology, Sahlgrenska University Hospital, 4 Bruna Straket, 41345, Gothenburg, Sweden.

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http://link.springer.com/10.1007/s00392-016-1043-4
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http://dx.doi.org/10.1007/s00392-016-1043-4DOI Listing
February 2017

Inflammatory Biomarkers Predict Heart Failure Severity and Prognosis in Patients With Heart Failure With Preserved Ejection Fraction: A Holistic Proteomic Approach.

Circ Cardiovasc Genet 2017 Feb;10(1)

From the Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden (C.H., C.L., L.H.L.); Department of Cardiology, Karolinska University Hospital, Stockholm, Sweden (C.H., C.L., L.H.L.); Cardiovascular and Metabolic Diseases, Innovative Medicines and Early Development Biotech Unit, AstraZeneca R&D, Mölndal, Sweden (E.M., L.-M.G.); Département de Cardiologie and CIC-IT U 804, Centre Hospitalier Universitaire de Rennes, France (E.D., J.-C.D.); and Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy at the University of Gothenburg, Sweden (L.-M.G.).

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https://www.ahajournals.org/doi/10.1161/CIRCGENETICS.116.001
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http://dx.doi.org/10.1161/CIRCGENETICS.116.001633DOI Listing
February 2017

Effects of nitroglycerine on coronary flow velocity before and during adenosine provocation.

Cardiovasc Ultrasound 2016 Dec 6;14(1):48. Epub 2016 Dec 6.

Dept of Molecular and Clinical Medicine, Institute of Medicine at Sahlgrenska Academy, University of Gothenburg, 41345, Gothenburg, Sweden.

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http://dx.doi.org/10.1186/s12947-016-0091-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5139021PMC
December 2016

Long non-coding RNA ANRIL regulates inflammatory responses as a novel component of NF-κB pathway.

RNA Biol 2016 ;13(1):98-108

a Laboratory of Nucleic Acid Technology, Institute of Molecular Medicine, Peking University , Beijing , 100871 , China.

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http://dx.doi.org/10.1080/15476286.2015.1122164DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4829310PMC
October 2016

Perilipin 5 is protective in the ischemic heart.

Int J Cardiol 2016 Sep 16;219:446-54. Epub 2016 Jun 16.

Department of Molecular and Clinical Medicine, Institute of Medicine, University of Gothenburg and Sahlgrenska University Hospital, Gothenburg, Sweden; Wallenberg Laboratory, Institute of Medicine, University of Gothenburg and Sahlgrenska University Hospital, Gothenburg, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.ijcard.2016.06.037DOI Listing
September 2016

Inhibition of soluble epoxide hydrolase alleviated atherosclerosis by reducing monocyte infiltration in Ldlr(-/-) mice.

J Mol Cell Cardiol 2016 09 3;98:128-37. Epub 2016 Aug 3.

Department of Physiology and Pathophysiology, Peking University Health Science Center, Beijing 100191, China; Collaborative Innovation Center of Tianjin for Medical Epigenetics and Department of Physiology and Pathophysiology, Tianjin Medical University, Tianjin 300070, China. Electronic address:

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http://dx.doi.org/10.1016/j.yjmcc.2016.08.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5559083PMC
September 2016

Coronary flow reserve as a link between exercise capacity, cardiac systolic and diastolic function.

Int J Cardiol 2016 Aug 3;217:161-6. Epub 2016 May 3.

Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden; AstraZeneca R&D, Mölndal, Sweden; Department of Clinical Physiology, Sahlgrenska University Hospital, Gothenburg, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.ijcard.2016.04.179DOI Listing
August 2016

Cardiometabolic risk loci share downstream cis- and trans-gene regulation across tissues and diseases.

Science 2016 Aug;353(6301):827-30

Department of Genetics and Genomic Sciences, The Icahn Institute for Genomics and Multiscale Biology Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York , NY 10029, USA. Clinical Gene Networks AB, Jungfrugatan 10, 114 44 Stockholm, Sweden. Department of Pathophysiology, Institute of Biomedicine and Translation Medicine, University of Tartu, Biomeedikum, Ravila 19, 50411, Tartu, Estonia. Division of Vascular Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Scheeles Väg 2, 171 77 Stockholm, Sweden.

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http://dx.doi.org/10.1126/science.aad6970DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5534139PMC
August 2016

Impaired Coronary and Renal Vascular Function in Spontaneously Type 2 Diabetic Leptin-Deficient Mice.

PLoS One 2015 22;10(6):e0130648. Epub 2015 Jun 22.

Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden; CVMD iMED, AstraZeneca R&D Mölndal, Mölndal, Sweden; Department of Clinical Physiology, Sahlgrenska University Hospital, Gothenburg, Sweden.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0130648PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4476758PMC
March 2016

Insulin Enhances Endothelial Function Throughout the Arterial Tree in Healthy But Not Metabolic Syndrome Subjects.

J Clin Endocrinol Metab 2016 Mar 12;101(3):1198-206. Epub 2016 Jan 12.

Departments of Medicine (L.A.J., L.H., N.R., B.L., J.J.K., K.A., E.J.B.) and Pharmacology (E.J.B.), University of Virginia School of Medicine, Charlottesville, Virginia 22908; Department of Molecular and Clinical Medicine (L.-M.G., H.U.W.), Institute of Medicine, Sahlgrenska Academy at the University of Gothenburg, SE-413 45 Gothenburg, Sweden; and CVMD iMED (L.-M.G.), Department of Research and Development, AstraZeneca, 431 83 Mölndal, Sweden.

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http://dx.doi.org/10.1210/jc.2015-3293DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4803154PMC
March 2016

Elevated Plasma Levels of MMP-12 Are Associated With Atherosclerotic Burden and Symptomatic Cardiovascular Disease in Subjects With Type 2 Diabetes.

Arterioscler Thromb Vasc Biol 2015 Jul 7;35(7):1723-31. Epub 2015 May 7.

From the Department of Clinical Sciences Malmö, Lund University, Malmö, Sweden (I.G., E.B., A.E., P.D., G.N.F., H.B., G.Ö., M.P., J.N.); Medical Research Institute, University of Dundee, Dundee, UK (H.M.C., F.K., H.C.L., F.A., J.B.); Institute of Biomedical and Clinical Science, Diabetes and Vascular Medicine, NIHR Exeter Clinical Research Facility and University of Exeter Medical School, Exeter, UK (A.C.S., K.A., F.C., K.G., D.S.); Department of Clinical and Experimental Medicine (A.N., S.P., E.V.) and Department of Surgical, Medical, Molecular and Critical Area Pathology (C.P., M.K.), University of Pisa, Pisa, Italy; and AstraZeneca, Cardiovascular and Metabolic Diseases, Mölndal, Sweden (L.-M.G., V.S.).

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http://dx.doi.org/10.1161/ATVBAHA.115.305631DOI Listing
July 2015

Endothelial function in a mouse model of myeloperoxidase deficiency.

Biomed Res Int 2014 23;2014:128046. Epub 2014 Feb 23.

Department of Physiology, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, P.O. Box 432, 405 30 Gothenburg, Sweden.

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http://dx.doi.org/10.1155/2014/128046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3950905PMC
January 2015

Characterization of VCAM-1-binding peptide-functionalized quantum dots for molecular imaging of inflamed endothelium.

PLoS One 2013 31;8(12):e83805. Epub 2013 Dec 31.

Science for Life Laboratory, Department of Applied Physics, Royal Institute of Technology, Stockholm, Sweden.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0083805PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877406PMC
September 2014

Non-invasive evaluation of coronary flow reserve with transthoracic Doppler echocardiography predicts the presence of significant stenosis in coronary arteries.

Int J Cardiol 2014 Sep 10;176(1):294-7. Epub 2014 Jul 10.

Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden; Department of Cardiology, Sahlgrenska University Hospital, Gothenburg, Sweden.

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http://dx.doi.org/10.1016/j.ijcard.2014.06.076DOI Listing
September 2014

Radial artery intima-media thickness predicts major cardiovascular events in patients with suspected coronary artery disease.

Eur Heart J Cardiovasc Imaging 2014 Jul 26;15(7):769-75. Epub 2014 Jan 26.

Department of Molecular and Clinical Medicine/Clinical Physiology, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, S-41345 Gothenburg, Sweden Translational Sciences, CVGI Innovative Medicine Unit, AstraZeneca R&D, S-43183 Mölndal, Sweden.

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http://dx.doi.org/10.1093/ehjci/jet285DOI Listing
July 2014

Different catecholamines induce different patterns of takotsubo-like cardiac dysfunction in an apparently afterload dependent manner.

Int J Cardiol 2014 Jun 15;174(2):330-6. Epub 2014 Apr 15.

Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska University Hospital, Gothenburg, Sweden; Department of Cardiology, Sahlgrenska University Hospital, Gothenburg, Sweden.

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http://dx.doi.org/10.1016/j.ijcard.2014.04.103DOI Listing
June 2014

Contrast echocardiography reveals apparently normal coronary perfusion in a rat model of stress-induced (Takotsubo) cardiomyopathy.

Eur Heart J Cardiovasc Imaging 2014 Feb 5;15(2):152-7. Epub 2013 Jul 5.

Department of Molecular and Clinical Medicine, Sahlgrenska Academy at University of Gothenburg, Bruna stråket 16, SE 413 45 Gothenburg, Sweden.

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http://ehjcimaging.oxfordjournals.org/content/ejechocard/15/
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http://ehjcimaging.oxfordjournals.org/cgi/doi/10.1093/ehjci/
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http://dx.doi.org/10.1093/ehjci/jet079DOI Listing
February 2014

Coronary flow reserve from mouse to man--from mechanistic understanding to future interventions.

J Cardiovasc Transl Res 2013 Oct 23;6(5):715-28. Epub 2013 Jul 23.

Department of Molecular and Clinical Medicine, Institute of Medicine at Sahlgrenska Academy, University of Gothenburg and Sahlgrenska University Hospital, Göteborg, Sweden,

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http://dx.doi.org/10.1007/s12265-013-9497-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3790920PMC
October 2013

Reply: To PMID 23312702.

J Am Coll Cardiol 2013 Aug 7;62(7):647. Epub 2013 Jun 7.

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http://dx.doi.org/10.1016/j.jacc.2013.05.039DOI Listing
August 2013

Ticagrelor enhances adenosine-induced coronary vasodilatory responses in humans.

J Am Coll Cardiol 2013 Feb 9;61(7):723-7. Epub 2013 Jan 9.

Department of Clinical and Molecular Medicine, Institution of Medicine, Sahlgrenska Academy, Göteborg University, Göteborg, Sweden.

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http://dx.doi.org/10.1016/j.jacc.2012.11.032DOI Listing
February 2013

High-resolution radial artery intima-media thickness and cardiovascular risk factors in patients with suspected coronary artery disease--comparison with common carotid artery intima-media thickness.

Atherosclerosis 2012 Mar 29;221(1):118-23. Epub 2011 Dec 29.

Department of Clinical Physiology, Sahlgrenska University Hospital, S-41345 Gothenburg, Sweden.

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http://dx.doi.org/10.1016/j.atherosclerosis.2011.12.035DOI Listing
March 2012

Increased interleukin-6 but not tumour necrosis factor-alpha predicts mortality in the population of elderly heart failure patients.

Exp Clin Cardiol 2008 ;13(1):19-24

Department of Molecular and Clinical Medicine, Wallenberg Laboratory, Institute of Medicine, Sahlgrenska Academy, Gothenburg University.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2435396PMC
July 2011

Longitudinal common carotid artery wall motion is associated with plaque burden in man and mouse.

Atherosclerosis 2011 Jul 3;217(1):120-4. Epub 2011 Mar 3.

The Department of Clinical Physiology, Sahlgrenska University Hospital, Sweden.

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http://linkinghub.elsevier.com/retrieve/pii/S002191501100210
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http://dx.doi.org/10.1016/j.atherosclerosis.2011.02.046DOI Listing
July 2011

Carotid artery longitudinal displacement predicts 1-year cardiovascular outcome in patients with suspected coronary artery disease.

Arterioscler Thromb Vasc Biol 2011 Jul 28;31(7):1668-74. Epub 2011 Apr 28.

Department of Clinical Physiology, Sahlgrenska University Hospital, S:413 45 Göteborg, Sweden.

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https://www.ahajournals.org/doi/10.1161/ATVBAHA.111.222901
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http://dx.doi.org/10.1161/ATVBAHA.111.222901DOI Listing
July 2011

Longitudinal wall motion of the common carotid artery can be assessed by velocity vector imaging.

Clin Physiol Funct Imaging 2011 Jan 23;31(1):32-8. Epub 2010 Sep 23.

The Department of Clinical Physiology, Sahlgrenska University Hospital, Göteborg, Sweden.

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http://dx.doi.org/10.1111/j.1475-097X.2010.00976.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3042148PMC
January 2011

Omega-3 fatty acid supplementation improves vascular function and reduces inflammation in obese adolescents.

Atherosclerosis 2010 Oct 21;212(2):580-5. Epub 2010 Jul 21.

Department of Clinical Physiology, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden.

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http://dx.doi.org/10.1016/j.atherosclerosis.2010.06.046DOI Listing
October 2010

High levels of soluble intercellular adhesion molecule-1, insulin resistance and saturated fatty acids are associated with endothelial dysfunction in healthy adolescents.

Atherosclerosis 2010 Aug 16;211(2):638-42. Epub 2010 Mar 16.

Department of Molecular and Clinical Medicine/Clinical Physiology, The Sahlgrenska Academy and University Hospital, University of Gothenburg, SE 41345 Gothenburg, Sweden.

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http://linkinghub.elsevier.com/retrieve/pii/S002191501000229
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http://dx.doi.org/10.1016/j.atherosclerosis.2010.03.013DOI Listing
August 2010

Increased intima thickness of the radial artery in individuals with prehypertension and hypertension.

Atherosclerosis 2010 Mar 13;209(1):147-51. Epub 2009 Sep 13.

Department of Internal Medicine, Varberg Hospital, Sweden.

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http://dx.doi.org/10.1016/j.atherosclerosis.2009.09.017DOI Listing
March 2010

Increased intima thickness of the radial artery in patients with coronary heart disease.

Vasc Med 2010 Feb 25;15(1):33-7. Epub 2009 Sep 25.

Department of Internal Medicine, Varberg Hospital, Varberg, Sweden.

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http://dx.doi.org/10.1177/1358863X09106619DOI Listing
February 2010

Muscle sympathetic nerve activity is related to a surrogate marker of endothelial function in healthy individuals.

PLoS One 2010 Feb 17;5(2):e9257. Epub 2010 Feb 17.

Institute of Neuroscience and Physiology, Department of Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0009257PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2822841PMC
February 2010

Protein disulfide isomerase increases in myocardial endothelial cells in mice exposed to chronic hypoxia: a stimulatory role in angiogenesis.

Am J Physiol Heart Circ Physiol 2009 Sep 17;297(3):H1078-86. Epub 2009 Jul 17.

Sahlgrenska Center for Cardiovascular and Metabolic Research, Wallenberg Laboratory, University of Gothenburg, SE-413 45 Göteborg, Sweden.

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http://www.physiology.org/doi/10.1152/ajpheart.00937.2008
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http://dx.doi.org/10.1152/ajpheart.00937.2008DOI Listing
September 2009

Evaluation of new automated gated-SPECT and echocardiographic methods for calculating left ventricular volumes and ejection fraction.

Int J Cardiol 2009 Aug 13;136(2):171-7. Epub 2008 Aug 13.

Department of Clinical Physiology, Sahlgrenska University Hospital, SE-413 45 Göteborg, Sweden.

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http://dx.doi.org/10.1016/j.ijcard.2008.04.082DOI Listing
August 2009

Sex differences in peripheral artery intima, media and intima media thickness in children and adolescents.

Atherosclerosis 2009 Mar 5;203(1):172-7. Epub 2008 Jun 5.

Department of Metabolism and Cardiovascular Research/Clinical Physiology, Sahlgrenska University Hospital, Göteborg, Sweden.

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http://linkinghub.elsevier.com/retrieve/pii/S002191500800388
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http://dx.doi.org/10.1016/j.atherosclerosis.2008.05.054DOI Listing
March 2009

High-salt diet combined with elevated angiotensin II accelerates atherosclerosis in apolipoprotein E-deficient mice.

J Hypertens 2009 Jan;27(1):41-7

Department of Molecular and Clinical Medicine, Clinical Physiology, The Sahlgrenska Academy, Göteborg University, Göteborg, Sweden.

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http://dx.doi.org/10.1097/hjh.0b013e328318697bDOI Listing
January 2009

Obese children show increased intimal wall thickness and decreased pulse wave velocity.

Clin Physiol Funct Imaging 2008 Sep 12;28(5):287-93. Epub 2008 May 12.

Department of Molecular and Clinical Medicine, Clinical Physiology, Sahlgrenska University Hospital, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden.

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http://dx.doi.org/10.1111/j.1475-097X.2008.00806.xDOI Listing
September 2008

Effects of social isolation and environmental enrichment on atherosclerosis in ApoE-/- mice.

Stress 2008 Sep;11(5):381-9

Department of Molecular and Clinical Medicine/Clinical Physiology, Institute of Medicine, The Sahlgrenska Academy, Götenborg University, Göteborg, Sweden.

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http://dx.doi.org/10.1080/10253890701824051DOI Listing
September 2008

Adenosine induces dilation of epicardial coronary arteries in mice: relationship between coronary flow velocity reserve and coronary flow reserve in vivo using transthoracic echocardiography.

Ultrasound Med Biol 2008 Jul 3;34(7):1053-62. Epub 2008 Mar 3.

Department of Neuroscience and Physiology, Institute of Physiology, the Sahlgrenska Academy, Göteborg University, Göteborg, Sweden.

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http://dx.doi.org/10.1016/j.ultrasmedbio.2007.12.004DOI Listing
July 2008

Epidermal growth factor levels are related to diastolic blood pressure and carotid artery stiffness.

Scand Cardiovasc J 2007 Oct;41(5):308-12

Department of Physiology, Institute of Physiology and Pharmacology, The Sahlgrenska Academy, Gothenburg University, Gothenburg, Sweden.

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http://dx.doi.org/10.1080/14017430701439508DOI Listing
October 2007

Imaging of atherosclerosis in WHHL rabbits using high-resolution ultrasound.

Ultrasound Med Biol 2007 May 26;33(5):720-6. Epub 2007 Mar 26.

Department of Clinical Physiology, Sahlgrenska University Hospital, Göteborg, Sweden.

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http://dx.doi.org/10.1016/j.ultrasmedbio.2006.11.012DOI Listing
May 2007

Increasing peripheral artery intima thickness from childhood to seniority.

Arterioscler Thromb Vasc Biol 2007 Mar 28;27(3):671-6. Epub 2006 Dec 28.

Department of Clinical Physiology, Sahlgrenska University Hospital/Sahlgrenska, SE-413 45 Göteborg, Sweden.

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http://dx.doi.org/10.1161/01.ATV.0000256468.95403.6fDOI Listing
March 2007

Non-invasive real-time imaging of atherosclerosis in mice using ultrasound biomicroscopy.

Atherosclerosis 2007 Feb 4;190(2):313-20. Epub 2006 May 4.

Department of Physiology, Institute of Physiology and Pharmacology, The Sahlgrenska Academy, Göteborg University, Göteborg, Sweden.

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http://dx.doi.org/10.1016/j.atherosclerosis.2006.03.035DOI Listing
February 2007

Increased atherosclerotic lesion area in apoE deficient mice overexpressing bovine growth hormone.

Atherosclerosis 2006 Oct 20;188(2):331-40. Epub 2005 Dec 20.

Department of Physiology, Göteborg University, Göteborg, Sweden.

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http://dx.doi.org/10.1016/j.atherosclerosis.2005.11.020DOI Listing
October 2006

Blood pressure is the major driving force for plaque formation in aortic-constricted ApoE-/- mice.

J Hypertens 2006 Oct;24(10):2001-8

Department of Physiology, Institute of Neuroscience and Physiology, The Sahlgrenska Academy, Göteborg University, Göteborg, Sweden.

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http://dx.doi.org/10.1097/01.hjh.0000244949.65040.deDOI Listing
October 2006

Platelet-derived growth factor B retention is essential for development of normal structure and function of conduit vessels and capillaries.

Cardiovasc Res 2006 Aug 25;71(3):557-65. Epub 2006 May 25.

Institute of Physiology and Pharmacology, Department of Physiology, Göteborg University, and RCEM and Wallenberg Laboratory, Sahlgrenska University Hospital, Sweden.

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http://dx.doi.org/10.1016/j.cardiores.2006.05.019DOI Listing
August 2006

Proximal to middle left coronary artery flow velocity ratio, as assessed using color Doppler echocardiography, predicts coronary artery atherosclerosis in mice.

Arterioscler Thromb Vasc Biol 2006 May 2;26(5):1126-31. Epub 2006 Mar 2.

Department of Physiology, Institute of Neuroscience and Physiology, The Sahlgrenska Academy, Göteborg University, Sweden.

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http://dx.doi.org/10.1161/01.ATV.0000216121.17190.a5DOI Listing
May 2006

Endothelial dysfunction in growth hormone transgenic mice.

Clin Sci (Lond) 2006 Feb;110(2):217-25

Department of Physiology, Institute of Physiology and Pharmacology, Sahlgrenska Academy, Göteborg University, Göteborg, Sweden.

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http://clinsci.org/lookup/doi/10.1042/CS20050281
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http://dx.doi.org/10.1042/CS20050281DOI Listing
February 2006

Physical exercise capacity is associated with coronary and peripheral vascular function in healthy young adults.

Am J Physiol Heart Circ Physiol 2005 Oct 3;289(4):H1627-34. Epub 2005 Jun 3.

Institute of Physiology and Pharmacology, Sahlgrenska Academy, Göteborg University, Göteborg, Sweden.

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http://dx.doi.org/10.1152/ajpheart.00135.2005DOI Listing
October 2005

Voluntary physical exercise and coronary flow velocity reserve: a transthoracic colour Doppler echocardiography study in spontaneously hypertensive rats.

Clin Sci (Lond) 2005 Sep;109(3):325-34

Department of Physiology, Institute of Physiology and Pharmacology, Göteborg University, Göteborg, Sweden.

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http://dx.doi.org/10.1042/CS20050052DOI Listing
September 2005

Gene expression profile and aortic vessel distensibility in voluntarily exercised spontaneously hypertensive rats: potential role of heat shock proteins.

Physiol Genomics 2005 Aug 24;22(3):319-26. Epub 2005 May 24.

Department of Physiology, Institute of Physiology and Pharmacology, Göteborg University, Sweden.

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http://dx.doi.org/10.1152/physiolgenomics.00073.2005DOI Listing
August 2005

Angiotensin II, type 2 receptor is not involved in the angiotensin II-mediated pro-atherogenic process in ApoE-/- mice.

J Hypertens 2005 Aug;23(8):1541-9

Department of Physiology, Institute of Physiology and Pharmacology, The Sahlgrenska Academy, Göteborg University, Göteborg, Sweden.

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http://dx.doi.org/10.1097/01.hjh.0000174078.95745.77DOI Listing
August 2005

Functional and morphologic imaging of coronary atherosclerosis in living mice using high-resolution color Doppler echocardiography and ultrasound biomicroscopy.

J Am Coll Cardiol 2005 Aug;46(4):720-7

Department of Physiology, Institute of Physiology and Pharmacology, The Sahlgrenska Academy, Göteborg University, Sweden.

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http://linkinghub.elsevier.com/retrieve/pii/S073510970501174
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http://dx.doi.org/10.1016/j.jacc.2005.04.053DOI Listing
August 2005

Haemodynamically significant plaque formation and regional endothelial dysfunction in cholesterol-fed ApoE-/- mice.

Clin Sci (Lond) 2005 Jun;108(6):531-8

Department of Physiology, Institute of Physiology and Pharmacology, The Sahlgrenska Academy, Göteborg University, Göteborg, Sweden.

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http://dx.doi.org/10.1042/CS20040322DOI Listing
June 2005

A short period of apnoea causes a marked increase in coronary flow velocity: a transthoracic pulsed wave Doppler study.

Clin Physiol Funct Imaging 2005 May;25(3):148-51

Department of Clinical Physiology, Sahlgrenska University Hospital, Göteborg, Sweden.

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http://doi.wiley.com/10.1111/j.1475-097X.2005.00605.x
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http://dx.doi.org/10.1111/j.1475-097X.2005.00605.xDOI Listing
May 2005

Voluntary physical exercise-induced vascular effects in spontaneously hypertensive rats.

Clin Sci (Lond) 2004 Dec;107(6):571-81

Department of Physiology, Institute of Physiology and Pharmacology, Göteborg University, Göteborg, Sweden.

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http://dx.doi.org/10.1042/CS20040171DOI Listing
December 2004

Amplitude and velocity of mitral annulus motion in rabbits.

Echocardiography 2004 May;21(4):313-7

Department of Clinical Physiology, Sahlgrenska University Hospital, Gothenburg, Sweden.

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http://doi.wiley.com/10.1111/j.0742-2822.2004.03111.x
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http://dx.doi.org/10.1111/j.0742-2822.2004.03111.xDOI Listing
May 2004

Non-invasive imaging of coronary arteries in living mice using high-resolution echocardiography.

Scand Cardiovasc J 2004 May;38(2):121-6

Department of Clinical Physiology, Cardiovascular Institute, Sahlgrenska University Hospital, SE-413 45 Göteborg, Sweden.

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http://www.tandfonline.com/doi/full/10.1080/1401743041002968
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http://dx.doi.org/10.1080/14017430410029680DOI Listing
May 2004

A technique to estimate the rate of whole body nitric oxide formation in conscious mice.

Nitric Oxide 2003 Sep;9(2):77-85

Department of Physiology, Sahlgrenska Academy, Göteborg University, PO Box 432, S-405 30, Göteborg, Sweden.

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September 2003

Intraluminal pressure modulates eicosanoid enzyme expression in vascular endothelium of intact human conduit vessels at physiological levels of shear stress.

J Hypertens 2002 Jan;20(1):63-70

Clinical Experimental Research Laboratory, Heart and Lung Institute, Sahlgrenska University Hospital/Ostra, Göteborg University, S-416 85 Göteborg, Sweden.

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http://dx.doi.org/10.1097/00004872-200201000-00010DOI Listing
January 2002