Lewis Whitehead

Lewis Whitehead

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Lewis Whitehead

Lewis Whitehead

Publications by authors named "Lewis Whitehead"

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Automated ligand- and structure-based protocol for in silico prediction of human serum albumin binding.

J Chem Inf Model 2013 Apr 2;53(4):907-22. Epub 2013 Apr 2.

Novartis Institutes for Biomedical Research, 100 Technology Square, Cambridge, Massachusetts 02143, USA.

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http://dx.doi.org/10.1021/ci3006098DOI Listing
April 2013

The chemical tuning of a weak zinc binding motif for histone deacetylase using electronic effects.

Chem Biol Drug Des 2012 Aug 15;80(2):203-14. Epub 2012 May 15.

Novartis Institutes of Biomedical Research, 100 Technology Square, Cambridge, MA 02139, USA.

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http://doi.wiley.com/10.1111/j.1747-0285.2012.01382.x
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http://dx.doi.org/10.1111/j.1747-0285.2012.01382.xDOI Listing
August 2012

An investigation into pharmaceutically relevant mutagenicity data and the influence on Ames predictive potential.

J Cheminform 2011 Nov 22;3:51. Epub 2011 Nov 22.

Novartis Institutes for Biomedical Research, 100 Technology Square, Cambridge, MA 02139, USA.

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http://dx.doi.org/10.1186/1758-2946-3-51DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3277490PMC
November 2011

Atomic-scale characterization of conformational changes in the preQ₁ riboswitch aptamer upon ligand binding.

J Mol Graph Model 2011 Sep 22;30:179-85. Epub 2011 Jul 22.

Novartis Institutes for BioMedical Research, Inc., 100 Technology Square & 250 Massachusetts Ave. Cambridge, MA 02139, USA.

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http://dx.doi.org/10.1016/j.jmgm.2011.07.006DOI Listing
September 2011

Avoidance of the Ames test liability for aryl-amines via computation.

Bioorg Med Chem 2011 May 3;19(10):3173-82. Epub 2011 Apr 3.

Novartis Institutes for Biomedical Research, Cambridge, MA 02139, USA.

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http://dx.doi.org/10.1016/j.bmc.2011.03.066DOI Listing
May 2011

Application of non-parametric regression to quantitative structure-activity relationships.

Bioorg Med Chem 2002 Apr;10(4):1037-41

School of Chemistry, University of Nottingham, University Park, NG7 2RD, Nottingham, UK.

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http://dx.doi.org/10.1016/s0968-0896(01)00359-5DOI Listing
April 2002