Lewis J Smith

Lewis J Smith

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Lewis J Smith

Lewis J Smith

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Soy isoflavones reduce asthma exacerbation in asthmatic patients with high PAI-1-producing genotypes.

J Allergy Clin Immunol 2019 Jul 29;144(1):109-117.e4. Epub 2019 Jan 29.

Division of Pulmonary and Critical Care Medicine, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Ill.

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http://dx.doi.org/10.1016/j.jaci.2019.01.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612283PMC
July 2019

A Longitudinal Cohort Study of Aspirin Use and Progression of Emphysema-like Lung Characteristics on CT Imaging: The MESA Lung Study.

Chest 2018 Jul 12;154(1):41-50. Epub 2017 Dec 12.

Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, NY; Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY.

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http://dx.doi.org/10.1016/j.chest.2017.11.031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6045779PMC
July 2018

Pulmonary artery to aorta ratio is associated with cardiac structure and functional changes in mild-to-moderate COPD.

Int J Chron Obstruct Pulmon Dis 2017 12;12:1439-1446. Epub 2017 May 12.

Division of Pulmonary and Critical Care Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL.

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http://dx.doi.org/10.2147/COPD.S131413DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5439958PMC
March 2018

The lower limit of normal a fixed ratio to assess airflow limitation: will the debate ever end?

Authors:
Lewis J Smith

Eur Respir J 2018 03 29;51(3). Epub 2018 Mar 29.

Division of Pulmonary and Critical Care Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA

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http://dx.doi.org/10.1183/13993003.00403-2018DOI Listing
March 2018

Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks.

Authors:
Florence Demenais Patricia Margaritte-Jeannin Kathleen C Barnes William O C Cookson Janine Altmüller Wei Ang R Graham Barr Terri H Beaty Allan B Becker John Beilby Hans Bisgaard Unnur Steina Bjornsdottir Eugene Bleecker Klaus Bønnelykke Dorret I Boomsma Emmanuelle Bouzigon Christopher E Brightling Myriam Brossard Guy G Brusselle Esteban Burchard Kristin M Burkart Andrew Bush Moira Chan-Yeung Kian Fan Chung Alexessander Couto Alves John A Curtin Adnan Custovic Denise Daley Johan C de Jongste Blanca E Del-Rio-Navarro Kathleen M Donohue Liesbeth Duijts Celeste Eng Johan G Eriksson Martin Farrall Yuliya Fedorova Bjarke Feenstra Manuel A Ferreira Maxim B Freidin Zofia Gajdos Jim Gauderman Ulrike Gehring Frank Geller Jon Genuneit Sina A Gharib Frank Gilliland Raquel Granell Penelope E Graves Daniel F Gudbjartsson Tari Haahtela Susan R Heckbert Dick Heederik Joachim Heinrich Markku Heliövaara John Henderson Blanca E Himes Hiroshi Hirose Joel N Hirschhorn Albert Hofman Patrick Holt Jouke Hottenga Thomas J Hudson Jennie Hui Medea Imboden Vladimir Ivanov Vincent W V Jaddoe Alan James Christer Janson Marjo-Riitta Jarvelin Deborah Jarvis Graham Jones Ingileif Jonsdottir Pekka Jousilahti Michael Kabesch Mika Kähönen David B Kantor Alexandra S Karunas Elza Khusnutdinova Gerard H Koppelman Anita L Kozyrskyj Eskil Kreiner Michiaki Kubo Rajesh Kumar Ashish Kumar Mikko Kuokkanen Lies Lahousse Tarja Laitinen Catherine Laprise Mark Lathrop Susanne Lau Young-Ae Lee Terho Lehtimäki Sébastien Letort Albert M Levin Guo Li Liming Liang Laura R Loehr Stephanie J London Daan W Loth Ani Manichaikul Ingo Marenholz Fernando J Martinez Melanie C Matheson Rasika A Mathias Kenji Matsumoto Hamdi Mbarek Wendy L McArdle Mads Melbye Erik Melén Deborah Meyers Sven Michel Hamida Mohamdi Arthur W Musk Rachel A Myers Maartje A E Nieuwenhuis Emiko Noguchi George T O'Connor Ludmila M Ogorodova Cameron D Palmer Aarno Palotie Julie E Park Craig E Pennell Göran Pershagen Alexey Polonikov Dirkje S Postma Nicole Probst-Hensch Valery P Puzyrev Benjamin A Raby Olli T Raitakari Adaikalavan Ramasamy Stephen S Rich Colin F Robertson Isabelle Romieu Muhammad T Salam Veikko Salomaa Vivi Schlünssen Robert Scott Polina A Selivanova Torben Sigsgaard Angela Simpson Valérie Siroux Lewis J Smith Maria Solodilova Marie Standl Kari Stefansson David P Strachan Bruno H Stricker Atsushi Takahashi Philip J Thompson Gudmar Thorleifsson Unnur Thorsteinsdottir Carla M T Tiesler Dara G Torgerson Tatsuhiko Tsunoda André G Uitterlinden Ralf J P van der Valk Amaury Vaysse Sailaja Vedantam Andrea von Berg Erika von Mutius Judith M Vonk Johannes Waage Nick J Wareham Scott T Weiss Wendy B White Magnus Wickman Elisabeth Widén Gonneke Willemsen L Keoki Williams Inge M Wouters James J Yang Jing Hua Zhao Miriam F Moffatt Carole Ober Dan L Nicolae

Nat Genet 2018 01 22;50(1):42-53. Epub 2017 Dec 22.

Departments of Statistics, Human Genetics and Medicine, Section of Genetic Medicine, University of Chicago, Chicago, IL, USA.

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http://www.nature.com/articles/s41588-017-0014-7
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http://dx.doi.org/10.1038/s41588-017-0014-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5901974PMC
January 2018

Rapid decline in lung function is temporally associated with greater metabolically active adiposity in a longitudinal study of healthy adults.

Thorax 2017 12 20;72(12):1113-1120. Epub 2017 Jul 20.

Department of Medicine, School of Medicine, University of New Mexico Health Sciences Center, Albuquerque, New Mexico, USA.

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http://dx.doi.org/10.1136/thoraxjnl-2016-209125DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158777PMC
December 2017

Leukotrienes and sex: strange bedfellows?

Authors:
Lewis J Smith

J Clin Invest 2017 Aug 24;127(8):2895-2896. Epub 2017 Jul 24.

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http://dx.doi.org/10.1172/JCI95717DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5531399PMC
August 2017

Large-scale genome-wide association studies and meta-analyses of longitudinal change in adult lung function.

PLoS One 2014 1;9(7):e100776. Epub 2014 Jul 1.

Division of Nutritional Sciences, Cornell University, Ithaca, New York, United States of America; Department of Health Care Policy and Research, Division of Biostatistics and Epidemiology, Weill Cornell Medical College, New York, New York, United States of America.

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http://repub.eur.nl/pub/55346/journal.pone.0100776.pdf
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http://dx.plos.org/10.1371/journal.pone.0100776
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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0100776PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4077649PMC
November 2015

Genome-wide association analysis identifies six new loci associated with forced vital capacity.

Authors:
Daan W Loth María Soler Artigas Sina A Gharib Louise V Wain Nora Franceschini Beate Koch Tess D Pottinger Albert Vernon Smith Qing Duan Chris Oldmeadow Mi Kyeong Lee David P Strachan Alan L James Jennifer E Huffman Veronique Vitart Adaikalavan Ramasamy Nicholas J Wareham Jaakko Kaprio Xin-Qun Wang Holly Trochet Mika Kähönen Claudia Flexeder Eva Albrecht Lorna M Lopez Kim de Jong Bharat Thyagarajan Alexessander Couto Alves Stefan Enroth Ernst Omenaas Peter K Joshi Tove Fall Ana Viñuela Lenore J Launer Laura R Loehr Myriam Fornage Guo Li Jemma B Wilk Wenbo Tang Ani Manichaikul Lies Lahousse Tamara B Harris Kari E North Alicja R Rudnicka Jennie Hui Xiangjun Gu Thomas Lumley Alan F Wright Nicholas D Hastie Susan Campbell Rajesh Kumar Isabelle Pin Robert A Scott Kirsi H Pietiläinen Ida Surakka Yongmei Liu Elizabeth G Holliday Holger Schulz Joachim Heinrich Gail Davies Judith M Vonk Mary Wojczynski Anneli Pouta Asa Johansson Sarah H Wild Erik Ingelsson Fernando Rivadeneira Henry Völzke Pirro G Hysi Gudny Eiriksdottir Alanna C Morrison Jerome I Rotter Wei Gao Dirkje S Postma Wendy B White Stephen S Rich Albert Hofman Thor Aspelund David Couper Lewis J Smith Bruce M Psaty Kurt Lohman Esteban G Burchard André G Uitterlinden Melissa Garcia Bonnie R Joubert Wendy L McArdle A Bill Musk Nadia Hansel Susan R Heckbert Lina Zgaga Joyce B J van Meurs Pau Navarro Igor Rudan Yeon-Mok Oh Susan Redline Deborah L Jarvis Jing Hua Zhao Taina Rantanen George T O'Connor Samuli Ripatti Rodney J Scott Stefan Karrasch Harald Grallert Nathan C Gaddis John M Starr Cisca Wijmenga Ryan L Minster David J Lederer Juha Pekkanen Ulf Gyllensten Harry Campbell Andrew P Morris Sven Gläser Christopher J Hammond Kristin M Burkart John Beilby Stephen B Kritchevsky Vilmundur Gudnason Dana B Hancock O Dale Williams Ozren Polasek Tatijana Zemunik Ivana Kolcic Marcy F Petrini Matthias Wjst Woo Jin Kim David J Porteous Generation Scotland Blair H Smith Anne Viljanen Markku Heliövaara John R Attia Ian Sayers Regina Hampel Christian Gieger Ian J Deary H Marike Boezen Anne Newman Marjo-Riitta Jarvelin James F Wilson Lars Lind Bruno H Stricker Alexander Teumer Timothy D Spector Erik Melén Marjolein J Peters Leslie A Lange R Graham Barr Ken R Bracke Fien M Verhamme Joohon Sung Pieter S Hiemstra Patricia A Cassano Akshay Sood Caroline Hayward Josée Dupuis Ian P Hall Guy G Brusselle Martin D Tobin Stephanie J London

Nat Genet 2014 Jul 15;46(7):669-77. Epub 2014 Jun 15.

1] Epidemiology Branch, National Institute of Environmental Health Sciences, US National Institutes of Health, US Department of Health and Human Services, Research Triangle Park, North Carolina, USA. [2].

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http://dx.doi.org/10.1038/ng.3011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4140093PMC
July 2014

Reply: body mass index is a stronger predictor than the metabolic syndrome for future asthma in women.

Am J Respir Crit Care Med 2014 Jan;189(2):232-3

1 University of New Mexico Health Sciences Center School of Medicine Albuquerque, New Mexico.

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http://dx.doi.org/10.1164/rccm.201308-1488LEDOI Listing
January 2014

Body mass index is a stronger predictor than the metabolic syndrome for future asthma in women. The longitudinal CARDIA study.

Am J Respir Crit Care Med 2013 Aug;188(3):319-26

Department of Medicine, University of New Mexico Health Sciences Center School of Medicine, Albuquerque, NM 87131, USA.

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http://dx.doi.org/10.1164/rccm.201303-0457OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5448505PMC
August 2013

Adult-onset asthma becomes the dominant phenotype among women by age 40 years. the longitudinal CARDIA study.

Ann Am Thorac Soc 2013 Jun;10(3):188-97

University of New Mexico Health Sciences Center School of Medicine, Department of Medicine, Albuquerque, NM 87131, USA.

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http://dx.doi.org/10.1513/AnnalsATS.201212-115OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3960903PMC
June 2013

Association of dietary soy genistein intake with lung function and asthma control: a post-hoc analysis of patients enrolled in a prospective multicentre clinical trial.

Prim Care Respir J 2012 Dec;21(4):398-404

Johns Hopkins University School of Medicine-Pulmonary and Critical Care Medicine, Johns Hopkins Asthma and Allergy Center, Baltimore, Maryland 21224-6801, USA.

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http://dx.doi.org/10.4104/pcrj.2012.00073DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3811067PMC
December 2012

Low serum adiponectin predicts future risk for asthma in women.

Am J Respir Crit Care Med 2012 Jul 6;186(1):41-7. Epub 2012 Apr 6.

Division of Pulmonary and Critical Care Medicine, University of New Mexico Health Sciences Center, School of Medicine, Department of Medicine, University of New Mexico, Albuquerque, NM 87131, USA.

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http://dx.doi.org/10.1164/rccm.201110-1767OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3400996PMC
July 2012

Reduced lung diffusion capacity in type 2 diabetes is independent of heart failure.

Diabetes Res Clin Pract 2012 Jun 20;96(3):e73-5. Epub 2012 Mar 20.

Department of Medicine, University of California, San Francisco, CA 94143-0131, USA.

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http://dx.doi.org/10.1016/j.diabres.2012.02.014DOI Listing
June 2012

Right heart structural changes are independently associated with exercise capacity in non-severe COPD.

PLoS One 2011 29;6(12):e29069. Epub 2011 Dec 29.

Pulmonary Hypertension Program, Division of Pulmonary and Critical Care Medicine, Northwestern University, Chicago, Illinois, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0029069PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3248404PMC
April 2012

Pulmonary hypertension in advanced chronic obstructive pulmonary disease.

Curr Opin Pulm Med 2012 Mar;18(2):138-43

Division of Pulmonary and Critical Care Medicine, Northwestern University, Chicago, Illinois, USA.

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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/MCP.0b013e32834f2093DOI Listing
March 2012

Rate of decline of forced vital capacity predicts future arterial hypertension: the Coronary Artery Risk Development in Young Adults Study.

Hypertension 2012 Feb 27;59(2):219-25. Epub 2011 Dec 27.

Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, 1300 South Second St, Minneapolis, MN 55454, USA.

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https://www.ahajournals.org/doi/10.1161/HYPERTENSIONAHA.111.
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http://dx.doi.org/10.1161/HYPERTENSIONAHA.111.184101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3269403PMC
February 2012

Risk factors for montelukast treatment failure in step-down therapy for controlled asthma.

J Asthma 2011 Dec 27;48(10):1051-7. Epub 2011 Oct 27.

Division of Pulmonary and Critical Care Medicine, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21224, USA.

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http://dx.doi.org/10.3109/02770903.2011.627488DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4277696PMC
December 2011

Serum Adiponectin is Associated with Adverse Outcomes of Asthma in Men but Not in Women.

Front Pharmacol 2011 5;2:55. Epub 2011 Oct 5.

University of New Mexico Health Sciences Center School of Medicine Albuquerque, NM, USA.

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http://dx.doi.org/10.3389/fphar.2011.00055DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3186942PMC
November 2011

Reduced diffusion lung capacity in patients with type 2 diabetes mellitus predicts hospitalization for pneumonia.

Diabetes Res Clin Pract 2011 Apr 14;92(1):e12-5. Epub 2011 Jan 14.

Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, United States.

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https://linkinghub.elsevier.com/retrieve/pii/S01688227100060
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http://dx.doi.org/10.1016/j.diabres.2010.12.012DOI Listing
April 2011

Effect of obesity on asthma phenotype is dependent upon asthma severity.

J Asthma 2011 Feb 22;48(1):98-104. Epub 2010 Nov 22.

Department of Pulmonary and Critical Care Medicine, Northshore University Health System, Evanston, IL, USA.

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http://dx.doi.org/10.3109/02770903.2010.534220DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4007205PMC
February 2011

Serum adiponectin is positively associated with lung function in young adults, independent of obesity: the CARDIA study.

Respir Res 2010 Dec 9;11:176. Epub 2010 Dec 9.

Department of Laboratory Medicine and Pathology, Medical School, University of Minnesota Minneapolis, MN 55455, USA.

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http://dx.doi.org/10.1186/1465-9921-11-176DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3014903PMC
December 2010

Anticholinergics for patients with asthma?

Authors:
Lewis J Smith

N Engl J Med 2010 Oct 19;363(18):1764-5. Epub 2010 Sep 19.

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http://dx.doi.org/10.1056/NEJMe1009429DOI Listing
October 2010

Systemic inflammation in young adults is associated with abnormal lung function in middle age.

PLoS One 2010 Jul 2;5(7):e11431. Epub 2010 Jul 2.

Asthma-Chronic Obstructive Pulmonary Disease Program, Division of Pulmonary and Critical Care Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0011431PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2896391PMC
July 2010

Prospective measurements of intra-abdominal volume and pulmonary function after repair of massive ventral hernias with the components separation technique.

Ann Surg 2010 May;251(5):981-8

Division of Plastic and Reconstructive Surgery, Department of Radiation Oncology, Northwestern University, Evanston, IL, USA.

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http://dx.doi.org/10.1097/SLA.0b013e3181d7707bDOI Listing
May 2010

Diet and asthma.

Curr Opin Pulm Med 2010 Jan;16(1):71-6

Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, USA.

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https://insights.ovid.com/crossref?an=00063198-201001000-000
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http://dx.doi.org/10.1097/MCP.0b013e3283323b73DOI Listing
January 2010

Obesity-asthma association: is it explained by systemic oxidant stress?

Chest 2009 Oct 10;136(4):1055-1062. Epub 2009 Jul 10.

Division of Epidemiology, University of Minnesota, Minneapolis, MN; Institute for Nutrition Research, University of Oslo, Oslo, Norway.

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http://dx.doi.org/10.1378/chest.09-0493DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2771042PMC
October 2009

Association of circulating adhesion molecules with lung function. The CARDIA study.

Chest 2009 Jun 18;135(6):1481-1487. Epub 2009 Feb 18.

Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, MN; Department of Nutrition, University of Oslo, Oslo, Norway. Electronic address:

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http://dx.doi.org/10.1378/chest.08-1753DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2821290PMC
June 2009

Longitudinal association of body mass index with lung function: the CARDIA study.

Respir Res 2008 Apr 4;9:31. Epub 2008 Apr 4.

Dept of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, Minnesota, USA.

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http://dx.doi.org/10.1186/1465-9921-9-31DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2386787PMC
April 2008

Plasma fibrinogen and lung function: the CARDIA Study.

Int J Epidemiol 2006 Aug 22;35(4):1001-8. Epub 2006 Mar 22.

Division of Epidemiology, School of Public Health, University of Minnesota, Minneapolis, 55454, USA.

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http://dx.doi.org/10.1093/ije/dyl049DOI Listing
August 2006

Dietary intake of soy genistein is associated with lung function in patients with asthma.

J Asthma 2004 ;41(8):833-43

Feinberg School of Medicine, Northwestern University, Evanston, Illinois, USA.

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January 2005