Lewis C Becker

Lewis C Becker

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Lewis C Becker

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White Matter Lesion Progression and Cognitive Function Over 5 Years in a Young Susceptible Population.

Neuroepidemiology 2017 30;49(1-2):62-63. Epub 2017 Aug 30.

The Johns Hopkins GeneSTAR Research Program, Departments of Neurology and Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

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http://dx.doi.org/10.1159/000480238DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5634942PMC
June 2019

The relationship of family history and risk of type 2 diabetes differs by ancestry.

Diabetes Metab 2019 06 21;45(3):261-267. Epub 2018 May 21.

The Johns Hopkins GeneSTAR Research Program, Department of Medicine, The Johns Hopkins Medical Institutions, 1830, East Monument Street, Room 8023, 21287 Baltimore, MD, USA.

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http://dx.doi.org/10.1016/j.diabet.2018.05.004DOI Listing
June 2019

Targeted deep sequencing of the PEAR1 locus for platelet aggregation in European and African American families.

Platelets 2019 19;30(3):380-386. Epub 2018 Mar 19.

a GeneSTAR Research Program Department of Medicine, Division of General Internal Medicine , Johns Hopkins University School of Medicine , Baltimore , MD , USA.

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http://dx.doi.org/10.1080/09537104.2018.1447659DOI Listing
April 2019

Genome-Wide Association Transethnic Meta-Analyses Identifies Novel Associations Regulating Coagulation Factor VIII and von Willebrand Factor Plasma Levels.

Circulation 2019 Jan;139(5):620-635

Department of Epidemiology, (A.P.R., B.M.P., N.L.S.), University of Washington, Seattle.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.118.034532DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6438386PMC
January 2019

Diabetes and Platelet Response to Low-Dose Aspirin.

J Clin Endocrinol Metab 2018 Dec;103(12):4599-4608

Division of Endocrinology, Diabetes & Metabolism, The Johns Hopkins University, Baltimore, Maryland.

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https://academic.oup.com/jcem/advance-article/doi/10.1210/jc
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http://dx.doi.org/10.1210/jc.2018-01254DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6232753PMC
December 2018

Whole exome sequencing in the Framingham Heart Study identifies rare variation in HYAL2 that influences platelet aggregation.

Thromb Haemost 2017 06 16;117(6):1083-1092. Epub 2017 Mar 16.

Andrew D. Johnson, Tenure Track Investigator, Population Sciences Branch, National Heart, Lung, and Blood Institute, The Framingham Heart Study, 73 Mt. Wayte Ave. Suite #2, Framingham, MA 01702, USA, Tel.: +1 508 663 4082, E-mail:

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http://dx.doi.org/10.1160/TH16-09-0677DOI Listing
June 2017

Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis.

Authors:
Frank J A van Rooij Rehan Qayyum Albert V Smith Yi Zhou Stella Trompet Toshiko Tanaka Margaux F Keller Li-Ching Chang Helena Schmidt Min-Lee Yang Ming-Huei Chen James Hayes Andrew D Johnson Lisa R Yanek Christian Mueller Leslie Lange James S Floyd Mohsen Ghanbari Alan B Zonderman J Wouter Jukema Albert Hofman Cornelia M van Duijn Karl C Desch Yasaman Saba Ayse B Ozel Beverly M Snively Jer-Yuarn Wu Reinhold Schmidt Myriam Fornage Robert J Klein Caroline S Fox Koichi Matsuda Naoyuki Kamatani Philipp S Wild David J Stott Ian Ford P Eline Slagboom Jaden Yang Audrey Y Chu Amy J Lambert André G Uitterlinden Oscar H Franco Edith Hofer David Ginsburg Bella Hu Brendan Keating Ursula M Schick Jennifer A Brody Jun Z Li Zhao Chen Tanja Zeller Jack M Guralnik Daniel I Chasman Luanne L Peters Michiaki Kubo Diane M Becker Jin Li Gudny Eiriksdottir Jerome I Rotter Daniel Levy Vera Grossmann Kushang V Patel Chien-Hsiun Chen Paul M Ridker Hua Tang Lenore J Launer Kenneth M Rice Ruifang Li-Gao Luigi Ferrucci Michelle K Evans Avik Choudhuri Eirini Trompouki Brian J Abraham Song Yang Atsushi Takahashi Yoichiro Kamatani Charles Kooperberg Tamara B Harris Sun Ha Jee Josef Coresh Fuu-Jen Tsai Dan L Longo Yuan-Tsong Chen Janine F Felix Qiong Yang Bruce M Psaty Eric Boerwinkle Lewis C Becker Dennis O Mook-Kanamori James G Wilson Vilmundur Gudnason Christopher J O'Donnell Abbas Dehghan L Adrienne Cupples Michael A Nalls Andrew P Morris Yukinori Okada Alexander P Reiner Leonard I Zon Santhi K Ganesh

Am J Hum Genet 2017 Jan 22;100(1):51-63. Epub 2016 Dec 22.

Division of Cardiovascular Medicine, Department of Internal Medicine, Department of Human Genetics, University of Michigan, 1500 E. Medical Center Drive, Ann Arbor, MI 48109, USA. Electronic address:

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http://www.cell.com/ajhg/pdf/S0002-9297(16)30520-1.pdf
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http://linkinghub.elsevier.com/retrieve/pii/S000292971630520
Publisher Site
http://dx.doi.org/10.1016/j.ajhg.2016.11.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5223059PMC
January 2017

Multiethnic Exome-Wide Association Study of Subclinical Atherosclerosis.

Authors:
Pradeep Natarajan Joshua C Bis Lawrence F Bielak Amanda J Cox Marcus Dörr Mary F Feitosa Nora Franceschini Xiuqing Guo Shih-Jen Hwang Aaron Isaacs Min A Jhun Maryam Kavousi Ruifang Li-Gao Leo-Pekka Lyytikäinen Riccardo E Marioni Ulf Schminke Nathan O Stitziel Hayato Tada Jessica van Setten Albert V Smith Dina Vojinovic Lisa R Yanek Jie Yao Laura M Yerges-Armstrong Najaf Amin Usman Baber Ingrid B Borecki J Jeffrey Carr Yii-Der Ida Chen L Adrienne Cupples Pim A de Jong Harry de Koning Bob D de Vos Ayse Demirkan Valentin Fuster Oscar H Franco Mark O Goodarzi Tamara B Harris Susan R Heckbert Gerardo Heiss Udo Hoffmann Albert Hofman Ivana Išgum J Wouter Jukema Mika Kähönen Sharon L R Kardia Brian G Kral Lenore J Launer Joe Massaro Roxana Mehran Braxton D Mitchell Thomas H Mosley Renée de Mutsert Anne B Newman Khanh-Dung Nguyen Kari E North Jeffrey R O'Connell Matthijs Oudkerk James S Pankow Gina M Peloso Wendy Post Michael A Province Laura M Raffield Olli T Raitakari Dermot F Reilly Fernando Rivadeneira Frits Rosendaal Samantha Sartori Kent D Taylor Alexander Teumer Stella Trompet Stephen T Turner Andre G Uitterlinden Dhananjay Vaidya Aad van der Lugt Uwe Völker Joanna M Wardlaw Christina L Wassel Stefan Weiss Mary K Wojczynski Diane M Becker Lewis C Becker Eric Boerwinkle Donald W Bowden Ian J Deary Abbas Dehghan Stephan B Felix Vilmundur Gudnason Terho Lehtimäki Rasika Mathias Dennis O Mook-Kanamori Bruce M Psaty Daniel J Rader Jerome I Rotter James G Wilson Cornelia M van Duijn Henry Völzke Sekar Kathiresan Patricia A Peyser Christopher J O'Donnell

Circ Cardiovasc Genet 2016 Dec 21;9(6):511-520. Epub 2016 Nov 21.

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http://dx.doi.org/10.1161/CIRCGENETICS.116.001572DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5418659PMC
December 2016

SCARB1 Gene Variants Are Associated With the Phenotype of Combined High High-Density Lipoprotein Cholesterol and High Lipoprotein (a).

Circ Cardiovasc Genet 2016 Oct 20;9(5):408-418. Epub 2016 Sep 20.

From the Department of Medicine, Johns Hopkins Medical Institutions, Baltimore, MD (X.Y., L.R.Y., D.M.B., R.A.M., L.C.B.); Lipoprotein Metabolism Section, Pulmonary and Vascular Medicine Branch, NHLBI, National Institutes of Health, Bethesda, MD (A.S., C.K., A.T.R.); and Copenhagen University Hospital, Faculty of Health Sciences, University of Copenhagen, Denmark (B.G.N., A.T.-H.).

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http://dx.doi.org/10.1161/CIRCGENETICS.116.001402DOI Listing
October 2016

Relation of Plasma Lipoprotein(a) to Subclinical Coronary Plaque Volumes, Three-Vessel and Left Main Coronary Disease, and Severe Coronary Stenoses in Apparently Healthy African-Americans With a Family History of Early-Onset Coronary Artery Disease.

Am J Cardiol 2016 09 5;118(5):656-61. Epub 2016 Jul 5.

Johns Hopkins GeneSTAR Research Program, Department of Medicine, The Johns Hopkins Medical Institutions, Baltimore, Maryland; Department of Radiology, The Johns Hopkins Medical Institutions, Baltimore, Maryland.

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http://dx.doi.org/10.1016/j.amjcard.2016.06.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991623PMC
September 2016

Exome Genotyping Identifies Pleiotropic Variants Associated with Red Blood Cell Traits.

Authors:
Nathalie Chami Ming-Huei Chen Andrew J Slater John D Eicher Evangelos Evangelou Salman M Tajuddin Latisha Love-Gregory Tim Kacprowski Ursula M Schick Akihiro Nomura Ayush Giri Samuel Lessard Jennifer A Brody Claudia Schurmann Nathan Pankratz Lisa R Yanek Ani Manichaikul Raha Pazoki Evelin Mihailov W David Hill Laura M Raffield Amber Burt Traci M Bartz Diane M Becker Lewis C Becker Eric Boerwinkle Jette Bork-Jensen Erwin P Bottinger Michelle L O'Donoghue David R Crosslin Simon de Denus Marie-Pierre Dubé Paul Elliott Gunnar Engström Michele K Evans James S Floyd Myriam Fornage He Gao Andreas Greinacher Vilmundur Gudnason Torben Hansen Tamara B Harris Caroline Hayward Jussi Hernesniemi Heather M Highland Joel N Hirschhorn Albert Hofman Marguerite R Irvin Mika Kähönen Ethan Lange Lenore J Launer Terho Lehtimäki Jin Li David C M Liewald Allan Linneberg Yongmei Liu Yingchang Lu Leo-Pekka Lyytikäinen Reedik Mägi Rasika A Mathias Olle Melander Andres Metspalu Nina Mononen Mike A Nalls Deborah A Nickerson Kjell Nikus Chris J O'Donnell Marju Orho-Melander Oluf Pedersen Astrid Petersmann Linda Polfus Bruce M Psaty Olli T Raitakari Emma Raitoharju Melissa Richard Kenneth M Rice Fernando Rivadeneira Jerome I Rotter Frank Schmidt Albert Vernon Smith John M Starr Kent D Taylor Alexander Teumer Betina H Thuesen Eric S Torstenson Russell P Tracy Ioanna Tzoulaki Neil A Zakai Caterina Vacchi-Suzzi Cornelia M van Duijn Frank J A van Rooij Mary Cushman Ian J Deary Digna R Velez Edwards Anne-Claire Vergnaud Lars Wallentin Dawn M Waterworth Harvey D White James G Wilson Alan B Zonderman Sekar Kathiresan Niels Grarup Tõnu Esko Ruth J F Loos Leslie A Lange Nauder Faraday Nada A Abumrad Todd L Edwards Santhi K Ganesh Paul L Auer Andrew D Johnson Alexander P Reiner Guillaume Lettre

Am J Hum Genet 2016 Jul 23;99(1):8-21. Epub 2016 Jun 23.

Department of Medicine, Université de Montréal, Montréal, QC H3T 1J4, Canada; Montreal Heart Institute, Montréal, QC H1T 1C8, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2016.05.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5005438PMC
July 2016

Platelet-Related Variants Identified by Exomechip Meta-analysis in 157,293 Individuals.

Authors:
John D Eicher Nathalie Chami Tim Kacprowski Akihiro Nomura Ming-Huei Chen Lisa R Yanek Salman M Tajuddin Ursula M Schick Andrew J Slater Nathan Pankratz Linda Polfus Claudia Schurmann Ayush Giri Jennifer A Brody Leslie A Lange Ani Manichaikul W David Hill Raha Pazoki Paul Elliot Evangelos Evangelou Ioanna Tzoulaki He Gao Anne-Claire Vergnaud Rasika A Mathias Diane M Becker Lewis C Becker Amber Burt David R Crosslin Leo-Pekka Lyytikäinen Kjell Nikus Jussi Hernesniemi Mika Kähönen Emma Raitoharju Nina Mononen Olli T Raitakari Terho Lehtimäki Mary Cushman Neil A Zakai Deborah A Nickerson Laura M Raffield Rakale Quarells Cristen J Willer Gina M Peloso Goncalo R Abecasis Dajiang J Liu Panos Deloukas Nilesh J Samani Heribert Schunkert Jeanette Erdmann Myriam Fornage Melissa Richard Jean-Claude Tardif John D Rioux Marie-Pierre Dube Simon de Denus Yingchang Lu Erwin P Bottinger Ruth J F Loos Albert Vernon Smith Tamara B Harris Lenore J Launer Vilmundur Gudnason Digna R Velez Edwards Eric S Torstenson Yongmei Liu Russell P Tracy Jerome I Rotter Stephen S Rich Heather M Highland Eric Boerwinkle Jin Li Ethan Lange James G Wilson Evelin Mihailov Reedik Mägi Joel Hirschhorn Andres Metspalu Tõnu Esko Caterina Vacchi-Suzzi Mike A Nalls Alan B Zonderman Michele K Evans Gunnar Engström Marju Orho-Melander Olle Melander Michelle L O'Donoghue Dawn M Waterworth Lars Wallentin Harvey D White James S Floyd Traci M Bartz Kenneth M Rice Bruce M Psaty J M Starr David C M Liewald Caroline Hayward Ian J Deary Andreas Greinacher Uwe Völker Thomas Thiele Henry Völzke Frank J A van Rooij André G Uitterlinden Oscar H Franco Abbas Dehghan Todd L Edwards Santhi K Ganesh Sekar Kathiresan Nauder Faraday Paul L Auer Alex P Reiner Guillaume Lettre Andrew D Johnson

Am J Hum Genet 2016 Jul 23;99(1):40-55. Epub 2016 Jun 23.

Population Sciences Branch, National Heart Lung and Blood Institute, The Framingham Heart Study, Framingham, MA 01702, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2016.05.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5005441PMC
July 2016

Large-Scale Exome-wide Association Analysis Identifies Loci for White Blood Cell Traits and Pleiotropy with Immune-Mediated Diseases.

Authors:
Salman M Tajuddin Ursula M Schick John D Eicher Nathalie Chami Ayush Giri Jennifer A Brody W David Hill Tim Kacprowski Jin Li Leo-Pekka Lyytikäinen Ani Manichaikul Evelin Mihailov Michelle L O'Donoghue Nathan Pankratz Raha Pazoki Linda M Polfus Albert Vernon Smith Claudia Schurmann Caterina Vacchi-Suzzi Dawn M Waterworth Evangelos Evangelou Lisa R Yanek Amber Burt Ming-Huei Chen Frank J A van Rooij James S Floyd Andreas Greinacher Tamara B Harris Heather M Highland Leslie A Lange Yongmei Liu Reedik Mägi Mike A Nalls Rasika A Mathias Deborah A Nickerson Kjell Nikus John M Starr Jean-Claude Tardif Ioanna Tzoulaki Digna R Velez Edwards Lars Wallentin Traci M Bartz Lewis C Becker Joshua C Denny Laura M Raffield John D Rioux Nele Friedrich Myriam Fornage He Gao Joel N Hirschhorn David C M Liewald Stephen S Rich Andre Uitterlinden Lisa Bastarache Diane M Becker Eric Boerwinkle Simon de Denus Erwin P Bottinger Caroline Hayward Albert Hofman Georg Homuth Ethan Lange Lenore J Launer Terho Lehtimäki Yingchang Lu Andres Metspalu Chris J O'Donnell Rakale C Quarells Melissa Richard Eric S Torstenson Kent D Taylor Anne-Claire Vergnaud Alan B Zonderman David R Crosslin Ian J Deary Marcus Dörr Paul Elliott Michele K Evans Vilmundur Gudnason Mika Kähönen Bruce M Psaty Jerome I Rotter Andrew J Slater Abbas Dehghan Harvey D White Santhi K Ganesh Ruth J F Loos Tõnu Esko Nauder Faraday James G Wilson Mary Cushman Andrew D Johnson Todd L Edwards Neil A Zakai Guillaume Lettre Alex P Reiner Paul L Auer

Am J Hum Genet 2016 Jul 23;99(1):22-39. Epub 2016 Jun 23.

Zilber School of Public Health, University of Wisconsin-Milwaukee, Milwaukee, WI 53205, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2016.05.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5005433PMC
July 2016

A meta-analysis of 120 246 individuals identifies 18 new loci for fibrinogen concentration.

Authors:
Paul S de Vries Daniel I Chasman Maria Sabater-Lleal Ming-Huei Chen Jennifer E Huffman Maristella Steri Weihong Tang Alexander Teumer Riccardo E Marioni Vera Grossmann Jouke J Hottenga Stella Trompet Martina Müller-Nurasyid Jing Hua Zhao Jennifer A Brody Marcus E Kleber Xiuqing Guo Jie Jin Wang Paul L Auer John R Attia Lisa R Yanek Tarunveer S Ahluwalia Jari Lahti Cristina Venturini Toshiko Tanaka Lawrence F Bielak Peter K Joshi Ares Rocanin-Arjo Ivana Kolcic Pau Navarro Lynda M Rose Christopher Oldmeadow Helene Riess Johanna Mazur Saonli Basu Anuj Goel Qiong Yang Mohsen Ghanbari Gonneke Willemsen Ann Rumley Edoardo Fiorillo Anton J M de Craen Anne Grotevendt Robert Scott Kent D Taylor Graciela E Delgado Jie Yao Annette Kifley Charles Kooperberg Rehan Qayyum Lorna M Lopez Tina L Berentzen Katri Räikkönen Massimo Mangino Stefania Bandinelli Patricia A Peyser Sarah Wild David-Alexandre Trégouët Alan F Wright Jonathan Marten Tatijana Zemunik Alanna C Morrison Bengt Sennblad Geoffrey Tofler Moniek P M de Maat Eco J C de Geus Gordon D Lowe Magdalena Zoledziewska Naveed Sattar Harald Binder Uwe Völker Melanie Waldenberger Kay-Tee Khaw Barbara Mcknight Jie Huang Nancy S Jenny Elizabeth G Holliday Lihong Qi Mark G Mcevoy Diane M Becker John M Starr Antti-Pekka Sarin Pirro G Hysi Dena G Hernandez Min A Jhun Harry Campbell Anders Hamsten Fernando Rivadeneira Wendy L Mcardle P Eline Slagboom Tanja Zeller Wolfgang Koenig Bruce M Psaty Talin Haritunians Jingmin Liu Aarno Palotie André G Uitterlinden David J Stott Albert Hofman Oscar H Franco Ozren Polasek Igor Rudan Pierre-Emmanuel Morange James F Wilson Sharon L R Kardia Luigi Ferrucci Tim D Spector Johan G Eriksson Torben Hansen Ian J Deary Lewis C Becker Rodney J Scott Paul Mitchell Winfried März Nick J Wareham Annette Peters Andreas Greinacher Philipp S Wild J Wouter Jukema Dorret I Boomsma Caroline Hayward Francesco Cucca Russell Tracy Hugh Watkins Alex P Reiner Aaron R Folsom Paul M Ridker Christopher J O'Donnell Nicholas L Smith David P Strachan Abbas Dehghan

Hum Mol Genet 2016 Jan 10;25(2):358-70. Epub 2015 Nov 10.

Department of Epidemiology,

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http://hmg.oxfordjournals.org/content/early/2015/12/08/hmg.d
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http://www.hmg.oxfordjournals.org/lookup/doi/10.1093/hmg/ddv
Publisher Site
http://dx.doi.org/10.1093/hmg/ddv454DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4715256PMC
January 2016

Effect of white matter lesions on manual dexterity in healthy middle-aged persons.

Neurology 2015 May 10;84(19):1920-6. Epub 2015 Apr 10.

From the Departments of Neurology (P.A.N.), Anesthesiology and Critical Care Medicine (P.A.N.), and Neurosurgery (P.A.N.), and Department of Medicine, Division of General Internal Medicine (L.R.Y., L.C.B., K.C.-D., B.G.K., D.V., D.M.B.), GeneSTAR Research Program; Department of Biomedical Engineering (M.B., J.L.C., J.P.), Johns Hopkins School of Medicine; and Department of Medicine, Division of Cardiology (L.C.B., B.G.K.), and Department of Radiology, Divisions of Diagnostic Radiology and Neuroradiology (D.Y.), The Johns Hopkins Medical Institutions, Baltimore, MD.

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http://dx.doi.org/10.1212/WNL.0000000000001557DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4433457PMC
May 2015

Genome-wide association study of platelet aggregation in African Americans.

BMC Genet 2015 May 30;16:58. Epub 2015 May 30.

Department of Medicine, Thomas Jefferson University, Jefferson Medical College, Philadelphia, Pennsylvania, 19107, USA.

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http://dx.doi.org/10.1186/s12863-015-0217-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4448541PMC
May 2015

Age differences in periventricular and deep white matter lesions.

Neurobiol Aging 2015 Apr 7;36(4):1653-1658. Epub 2015 Jan 7.

Division of General Internal Medicine, Department of Medicine, GeneSTAR Research Program, Johns Hopkins School of Medicine, Baltimore, MD, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S01974580150000
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http://dx.doi.org/10.1016/j.neurobiolaging.2015.01.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4380525PMC
April 2015

Greater collagen-induced platelet aggregation following cyclooxygenase 1 inhibition predicts incident acute coronary syndromes.

Clin Transl Sci 2015 Feb 25;8(1):17-22. Epub 2014 Jul 25.

GeneSTAR Research Program, Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

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http://dx.doi.org/10.1111/cts.12195DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4305501PMC
February 2015

Noncalcified coronary plaque volumes in healthy people with a family history of early onset coronary artery disease.

Circ Cardiovasc Imaging 2014 May 27;7(3):446-53. Epub 2014 Feb 27.

From the Johns Hopkins GeneSTAR Research Program, Department of Medicine (B.G.K., L.C.B., D.V., L.R.Y., R.Q., T.F.M., D.M.B.) and Department of Radiology (S.L.Z., E.K.F.), The Johns Hopkins Medical Institutions, Baltimore, MD; and the Biomedical Imaging Research Institute, Department of Biomedical Sciences (D.D.) and Departments of Imaging and Medicine (D.S.B.), Cedars-Sinai Medical Center, Los Angeles, CA.

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http://dx.doi.org/10.1161/CIRCIMAGING.113.000980DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4419782PMC
May 2014

Genome-wide association study for circulating tissue plasminogen activator levels and functional follow-up implicates endothelial STXBP5 and STX2.

Authors:
Jie Huang Jennifer E Huffman Munekazu Yamakuchi Munekazu Yamkauchi Stella Trompet Folkert W Asselbergs Maria Sabater-Lleal David-Alexandre Trégouët Wei-Min Chen Nicholas L Smith Marcus E Kleber So-Youn Shin Diane M Becker Weihong Tang Abbas Dehghan Andrew D Johnson Vinh Truong Lasse Folkersen Qiong Yang Tiphaine Oudot-Mellkah Brendan M Buckley Jason H Moore Frances M K Williams Harry Campbell Günther Silbernagel Veronique Vitart Igor Rudan Geoffrey H Tofler Gerjan J Navis Anita Destefano Alan F Wright Ming-Huei Chen Anton J M de Craen Bradford B Worrall Alicja R Rudnicka Ann Rumley Ebony B Bookman Bruce M Psaty Fang Chen Keith L Keene Oscar H Franco Bernhard O Böhm Andre G Uitterlinden Angela M Carter J Wouter Jukema Naveed Sattar Joshua C Bis Mohammad A Ikram Michèle M Sale Barbara McKnight Myriam Fornage Ian Ford Kent Taylor P Eline Slagboom Wendy L McArdle Fang-Chi Hsu Anders Franco-Cereceda Alison H Goodall Lisa R Yanek Karen L Furie Mary Cushman Albert Hofman Jacqueline C M Witteman Aaron R Folsom Saonli Basu Nena Matijevic Wiek H van Gilst James F Wilson Rudi G J Westendorp Sekar Kathiresan Muredach P Reilly Russell P Tracy Ozren Polasek Bernhard R Winkelmann Peter J Grant Hans L Hillege Francois Cambien David J Stott Gordon D Lowe Timothy D Spector James B Meigs Winfried Marz Per Eriksson Lewis C Becker Pierre-Emmanuel Morange Nicole Soranzo Scott M Williams Caroline Hayward Pim van der Harst Anders Hamsten Charles J Lowenstein David P Strachan Christopher J O'Donnell

Arterioscler Thromb Vasc Biol 2014 May 27;34(5):1093-101. Epub 2014 Feb 27.

From National Heart, Lung, and Blood Institute's Framingham Heart Study, Framingham, MA (J.H., A.D.J., C.J.O.); Division of Intramural Research, National Heart, Lung, and Blood Institute, Bethesda, MD (J.H., A.D.J., C.J.O.); MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh, Scotland, United Kingdom (J.E.H., V.V., A.F.W., C.H.); The Aab Cardiovascular Research Institute, Department of Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY (M.Y., C.J.L.); Departments of Cardiology (S.T., J.W.J.), Gerontology and Geriatrics (S.T., A.J.M.d.C., R.G.J.W.), and Molecular Epidemiology (P.E.S.), Leiden University Medical Center, the Netherlands; Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands (F.W.A.); Durrer Center for Cardiogenetic Research, ICIN-Netherlands Heart Institute, Utrecht, the Netherlands (F.W.A.); Institute of Cardiovascular Science, Faculty of Population Health Sciences, University College London, London, United Kingdom (F.W.A.); Cardiovascular Genetics and Genomics Group, Atherosclerosis Research Unit, Department of Medicine (M.S.-L., L.F., P.E., A.H.), Karolinska Institutet, Karolinska University Hospital, Solna, Stockholm, Sweden; INSERM UMRS 937, Pierre et Marie Curie University, Paris, France (D.-A.T., V.T., T.O.M., F.C.); ICAN Institute for Cardiometabolism and Nutrion, Paris, France (D.-A.T., V.T., F.C.); Departments of Public Health Sciences (W.M.C., B.B.W., F.C.) and Biochemistry and Molecular Genetics (M.M.S.), Center for Public Health Genomics, University of Virginia, Charlottesville, VA; Departments of Epidemiology (N.L.S., B.M.P., B.M.), Medicine (B.M.P., J.C.B.), and Health Services (B.M.P.), University of Washington, Seattle, WA; Group Health Research Institute, Group Health Cooperative, Seattle, WA (N.L.S., B.M.P.); Seattle Epidemiologic Research and Information Center, VA Office of Research and

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http://dx.doi.org/10.1161/ATVBAHA.113.302088DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4009733PMC
May 2014

A Simple Scalable Association Hypothesis Test Combining Gene-wide Evidence From Multiple Polymorphisms.

Br J Med Med Res 2014 Mar;4(6):1413-1422

Johns Hopkins School of Medicine, Department of Medicine, Baltimore, MD.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3969754PMC
March 2014

Targeted deep resequencing identifies coding variants in the PEAR1 gene that play a role in platelet aggregation.

PLoS One 2013 21;8(5):e64179. Epub 2013 May 21.

Genometrics Section, Inherited Disease Research Branch, National Human Genome Research Institute, National Institutes of Health, Baltimore, Maryland, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0064179PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3660448PMC
December 2013

Effect of positive well-being on incidence of symptomatic coronary artery disease.

Am J Cardiol 2013 Oct 28;112(8):1120-5. Epub 2013 Jun 28.

GeneSTAR Research Program, Division of General Internal Medicine, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland. Electronic address:

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http://dx.doi.org/10.1016/j.amjcard.2013.05.055DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3788860PMC
October 2013

Relation of subclinical coronary artery atherosclerosis to cerebral white matter disease in healthy subjects from families with early-onset coronary artery disease.

Am J Cardiol 2013 Sep 3;112(6):747-52. Epub 2013 Jun 3.

Division of Cardiology, Department of Medicine, Johns Hopkins GeneSTAR Research Program, The Johns Hopkins Medical Institutions, Baltimore, MD, USA.

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September 2013

Scavenger receptor-BI is a receptor for lipoprotein(a).

J Lipid Res 2013 Sep 29;54(9):2450-7. Epub 2013 Jun 29.

Cardiology Division, Department of Medicine, Johns Hopkins Medical Institutions, Baltimore, MD, USA.

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September 2013

Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease.

Authors:
Maria Sabater-Lleal Jie Huang Daniel Chasman Silvia Naitza Abbas Dehghan Andrew D Johnson Alexander Teumer Alex P Reiner Lasse Folkersen Saonli Basu Alicja R Rudnicka Stella Trompet Anders Mälarstig Jens Baumert Joshua C Bis Xiuqing Guo Jouke J Hottenga So-Youn Shin Lorna M Lopez Jari Lahti Toshiko Tanaka Lisa R Yanek Tiphaine Oudot-Mellakh James F Wilson Pau Navarro Jennifer E Huffman Tatijana Zemunik Susan Redline Reena Mehra Drazen Pulanic Igor Rudan Alan F Wright Ivana Kolcic Ozren Polasek Sarah H Wild Harry Campbell J David Curb Robert Wallace Simin Liu Charles B Eaton Diane M Becker Lewis C Becker Stefania Bandinelli Katri Räikkönen Elisabeth Widen Aarno Palotie Myriam Fornage David Green Myron Gross Gail Davies Sarah E Harris David C Liewald John M Starr Frances M K Williams Peter J Grant Timothy D Spector Rona J Strawbridge Angela Silveira Bengt Sennblad Fernando Rivadeneira Andre G Uitterlinden Oscar H Franco Albert Hofman Jenny van Dongen Gonneke Willemsen Dorret I Boomsma Jie Yao Nancy Swords Jenny Talin Haritunians Barbara McKnight Thomas Lumley Kent D Taylor Jerome I Rotter Bruce M Psaty Annette Peters Christian Gieger Thomas Illig Anne Grotevendt Georg Homuth Henry Völzke Thomas Kocher Anuj Goel Maria Grazia Franzosi Udo Seedorf Robert Clarke Maristella Steri Kirill V Tarasov Serena Sanna David Schlessinger David J Stott Naveed Sattar Brendan M Buckley Ann Rumley Gordon D Lowe Wendy L McArdle Ming-Huei Chen Geoffrey H Tofler Jaejoon Song Eric Boerwinkle Aaron R Folsom Lynda M Rose Anders Franco-Cereceda Martina Teichert M Arfan Ikram Thomas H Mosley Steve Bevan Martin Dichgans Peter M Rothwell Cathie L M Sudlow Jemma C Hopewell John C Chambers Danish Saleheen Jaspal S Kooner John Danesh Christopher P Nelson Jeanette Erdmann Muredach P Reilly Sekar Kathiresan Heribert Schunkert Pierre-Emmanuel Morange Luigi Ferrucci Johan G Eriksson David Jacobs Ian J Deary Nicole Soranzo Jacqueline C M Witteman Eco J C de Geus Russell P Tracy Caroline Hayward Wolfgang Koenig Francesco Cucca J Wouter Jukema Per Eriksson Sudha Seshadri Hugh S Markus Hugh Watkins Nilesh J Samani Henri Wallaschofski Nicholas L Smith David Tregouet Paul M Ridker Weihong Tang David P Strachan Anders Hamsten Christopher J O'Donnell

Circulation 2013 Sep 22;128(12):1310-24. Epub 2013 Aug 22.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3842025PMC
September 2013

Genome-wide association analysis of blood-pressure traits in African-ancestry individuals reveals common associated genes in African and non-African populations.

Authors:
Nora Franceschini Ervin Fox Zhaogong Zhang Todd L Edwards Michael A Nalls Yun Ju Sung Bamidele O Tayo Yan V Sun Omri Gottesman Adebawole Adeyemo Andrew D Johnson J Hunter Young Ken Rice Qing Duan Fang Chen Yun Li Hua Tang Myriam Fornage Keith L Keene Jeanette S Andrews Jennifer A Smith Jessica D Faul Zhang Guangfa Wei Guo Yu Liu Sarah S Murray Solomon K Musani Sathanur Srinivasan Digna R Velez Edwards Heming Wang Lewis C Becker Pascal Bovet Murielle Bochud Ulrich Broeckel Michel Burnier Cara Carty Daniel I Chasman Georg Ehret Wei-Min Chen Guanjie Chen Wei Chen Jingzhong Ding Albert W Dreisbach Michele K Evans Xiuqing Guo Melissa E Garcia Rich Jensen Margaux F Keller Guillaume Lettre Vaneet Lotay Lisa W Martin Jason H Moore Alanna C Morrison Thomas H Mosley Adesola Ogunniyi Walter Palmas George Papanicolaou Alan Penman Joseph F Polak Paul M Ridker Babatunde Salako Andrew B Singleton Daniel Shriner Kent D Taylor Ramachandran Vasan Kerri Wiggins Scott M Williams Lisa R Yanek Wei Zhao Alan B Zonderman Diane M Becker Gerald Berenson Eric Boerwinkle Erwin Bottinger Mary Cushman Charles Eaton Fredrik Nyberg Gerardo Heiss Joel N Hirschhron Virginia J Howard Konrad J Karczewsk Matthew B Lanktree Kiang Liu Yongmei Liu Ruth Loos Karen Margolis Michael Snyder Bruce M Psaty Nicholas J Schork David R Weir Charles N Rotimi Michele M Sale Tamara Harris Sharon L R Kardia Steven C Hunt Donna Arnett Susan Redline Richard S Cooper Neil J Risch D C Rao Jerome I Rotter Aravinda Chakravarti Alex P Reiner Daniel Levy Brendan J Keating Xiaofeng Zhu

Am J Hum Genet 2013 Sep 22;93(3):545-54. Epub 2013 Aug 22.

Department of Epidemiology, University of North Carolina at Chapel Hill, NC 27599, USA.

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http://dx.doi.org/10.1016/j.ajhg.2013.07.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3769920PMC
September 2013

The robustness of generalized estimating equations for association tests in extended family data.

Hum Hered 2012 3;74(1):17-26. Epub 2012 Oct 3.

Genometrics Section, Inherited Disease Research Branch, National Human Genome Research Institute, National Institutes of Health, Baltimore, MD 21205, USA.

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April 2013

Genome-wide association study for circulating levels of PAI-1 provides novel insights into its regulation.

Blood 2012 Dec 18;120(24):4873-81. Epub 2012 Sep 18.

National Heart, Lung, and Blood Institute (NHBLI) Framingham Heart Study, Framingham, MA 01702, USA.

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December 2012

Response to catecholamine stimulation of polymorphisms of the beta-1 and beta-2 adrenergic receptors.

Am J Cardiol 2012 Oct 27;110(7):1001-7. Epub 2012 Jun 27.

Division of Cardiology, Department of Medicine, the Johns Hopkins University, Baltimore, Maryland, USA.

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October 2012

Ethnic-specific determinants of exercise capacity in a healthy high-risk population.

Med Sci Sports Exerc 2012 Jun;44(6):1150-6

Division of General Internal Medicine, Johns Hopkins Medical Institutions, Baltimore,MD 21287, USA.

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June 2012

Activation of Stat3 in endothelial cells following hypoxia-reoxygenation is mediated by Rac1 and protein Kinase C.

Biochim Biophys Acta 2012 May;1823(5):997-1006

Division of Cardiology, Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3392026PMC
May 2012

Severity of inducible myocardial ischemia predicts incident acute coronary syndromes in asymptomatic individuals with a family history of premature coronary artery disease.

J Nucl Cardiol 2012 Feb 12;19(1):28-36. Epub 2011 Nov 12.

Division of Cardiology, Department of Medicine, The Johns Hopkins GeneSTAR Research Program, The Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3266988PMC
February 2012

Silent myocardial ischaemia and long-term coronary artery disease outcomes in apparently healthy people from families with early-onset ischaemic heart disease.

Eur Heart J 2011 Nov 23;32(22):2766-72. Epub 2011 Jul 23.

The Johns Hopkins GeneSTAR Research Program, Division of Cardiology, Department of Medicine, The Johns Hopkins Medical Institutions, 1830 East Monument Street, Room 8023, Baltimore, MD 21287, USA.

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November 2011

Identification, replication, and fine-mapping of Loci associated with adult height in individuals of african ancestry.

PLoS Genet 2011 Oct 6;7(10):e1002298. Epub 2011 Oct 6.

Montreal Heart Institute, Montréal, Canada.

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October 2011

Ischemic preconditioning attenuates mitochondrial localization of PTEN induced by ischemia-reperfusion.

Am J Physiol Heart Circ Physiol 2011 Jun 18;300(6):H2177-86. Epub 2011 Mar 18.

720 Rutland Ave., Ross 333, Baltimore, MD 21205, USA.

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http://dx.doi.org/10.1152/ajpheart.01138.2010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3119092PMC
June 2011

Polymorphisms of the beta adrenergic receptor predict left ventricular remodeling following acute myocardial infarction.

Cardiovasc Drugs Ther 2011 Jun;25(3):251-8

Division of Cardiology, Department of Medicine, The Johns Hopkins Medical Institutions, Baltimore, MD, USA.

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June 2011

Abnormalities in arterial-ventricular coupling in older healthy persons are attenuated by sodium nitroprusside.

Am J Physiol Heart Circ Physiol 2011 May 4;300(5):H1914-22. Epub 2011 Mar 4.

Laboratory of Cardiovascular Science, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, USA.

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http://www.physiology.org/doi/10.1152/ajpheart.01048.2010
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3094083PMC
May 2011

Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease.

Authors:
Heribert Schunkert Inke R König Sekar Kathiresan Muredach P Reilly Themistocles L Assimes Hilma Holm Michael Preuss Alexandre F R Stewart Maja Barbalic Christian Gieger Devin Absher Zouhair Aherrahrou Hooman Allayee David Altshuler Sonia S Anand Karl Andersen Jeffrey L Anderson Diego Ardissino Stephen G Ball Anthony J Balmforth Timothy A Barnes Diane M Becker Lewis C Becker Klaus Berger Joshua C Bis S Matthijs Boekholdt Eric Boerwinkle Peter S Braund Morris J Brown Mary Susan Burnett Ian Buysschaert John F Carlquist Li Chen Sven Cichon Veryan Codd Robert W Davies George Dedoussis Abbas Dehghan Serkalem Demissie Joseph M Devaney Patrick Diemert Ron Do Angela Doering Sandra Eifert Nour Eddine El Mokhtari Stephen G Ellis Roberto Elosua James C Engert Stephen E Epstein Ulf de Faire Marcus Fischer Aaron R Folsom Jennifer Freyer Bruna Gigante Domenico Girelli Solveig Gretarsdottir Vilmundur Gudnason Jeffrey R Gulcher Eran Halperin Naomi Hammond Stanley L Hazen Albert Hofman Benjamin D Horne Thomas Illig Carlos Iribarren Gregory T Jones J Wouter Jukema Michael A Kaiser Lee M Kaplan John J P Kastelein Kay-Tee Khaw Joshua W Knowles Genovefa Kolovou Augustine Kong Reijo Laaksonen Diether Lambrechts Karin Leander Guillaume Lettre Mingyao Li Wolfgang Lieb Christina Loley Andrew J Lotery Pier M Mannucci Seraya Maouche Nicola Martinelli Pascal P McKeown Christa Meisinger Thomas Meitinger Olle Melander Pier Angelica Merlini Vincent Mooser Thomas Morgan Thomas W Mühleisen Joseph B Muhlestein Thomas Münzel Kiran Musunuru Janja Nahrstaedt Christopher P Nelson Markus M Nöthen Oliviero Olivieri Riyaz S Patel Chris C Patterson Annette Peters Flora Peyvandi Liming Qu Arshed A Quyyumi Daniel J Rader Loukianos S Rallidis Catherine Rice Frits R Rosendaal Diana Rubin Veikko Salomaa M Lourdes Sampietro Manj S Sandhu Eric Schadt Arne Schäfer Arne Schillert Stefan Schreiber Jürgen Schrezenmeir Stephen M Schwartz David S Siscovick Mohan Sivananthan Suthesh Sivapalaratnam Albert Smith Tamara B Smith Jaapjan D Snoep Nicole Soranzo John A Spertus Klaus Stark Kathy Stirrups Monika Stoll W H Wilson Tang Stephanie Tennstedt Gudmundur Thorgeirsson Gudmar Thorleifsson Maciej Tomaszewski Andre G Uitterlinden Andre M van Rij Benjamin F Voight Nick J Wareham George A Wells H-Erich Wichmann Philipp S Wild Christina Willenborg Jaqueline C M Witteman Benjamin J Wright Shu Ye Tanja Zeller Andreas Ziegler Francois Cambien Alison H Goodall L Adrienne Cupples Thomas Quertermous Winfried März Christian Hengstenberg Stefan Blankenberg Willem H Ouwehand Alistair S Hall Panos Deloukas John R Thompson Kari Stefansson Robert Roberts Unnur Thorsteinsdottir Christopher J O'Donnell Ruth McPherson Jeanette Erdmann Nilesh J Samani

Nat Genet 2011 Mar 6;43(4):333-8. Epub 2011 Mar 6.

Universität zu Lübeck, Medizinische Klinik II, Lübeck, Germany.

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March 2011

Lack of association between the Trp719Arg polymorphism in kinesin-like protein-6 and coronary artery disease in 19 case-control studies.

Authors:
Themistocles L Assimes Hilma Hólm Sekar Kathiresan Muredach P Reilly Gudmar Thorleifsson Benjamin F Voight Jeanette Erdmann Christina Willenborg Dhananjay Vaidya Changchun Xie Chris C Patterson Thomas M Morgan Mary Susan Burnett Mingyao Li Mark A Hlatky Joshua W Knowles John R Thompson Devin Absher Carlos Iribarren Alan Go Stephen P Fortmann Stephen Sidney Neil Risch Hua Tang Richard M Myers Klaus Berger Monika Stoll Svati H Shah Gudmundur Thorgeirsson Karl Andersen Aki S Havulinna J Enrique Herrera Nauder Faraday Yoonhee Kim Brian G Kral Rasika A Mathias Ingo Ruczinski Bhoom Suktitipat Alexander F Wilson Lisa R Yanek Lewis C Becker Patrick Linsel-Nitschke Wolfgang Lieb Inke R König Christian Hengstenberg Marcus Fischer Klaus Stark Wibke Reinhard Janina Winogradow Martina Grassl Anika Grosshennig Michael Preuss Stefan Schreiber H-Erich Wichmann Christa Meisinger Jean Yee Yechiel Friedlander Ron Do James B Meigs Gordon Williams David M Nathan Calum A MacRae Liming Qu Robert L Wilensky William H Matthai Atif N Qasim Hakon Hakonarson Augusto D Pichard Kenneth M Kent Lowell Satler Joseph M Lindsay Ron Waksman Christopher W Knouff Dawn M Waterworth Max C Walker Vincent E Mooser Jaume Marrugat Gavin Lucas Isaac Subirana Joan Sala Rafael Ramos Nicola Martinelli Oliviero Olivieri Elisabetta Trabetti Giovanni Malerba Pier Franco Pignatti Candace Guiducci Daniel Mirel Melissa Parkin Joel N Hirschhorn Rosanna Asselta Stefano Duga Kiran Musunuru Mark J Daly Shaun Purcell Sandra Eifert Peter S Braund Benjamin J Wright Anthony J Balmforth Stephen G Ball Willem H Ouwehand Panos Deloukas Michael Scholz Francois Cambien Andreas Huge Thomas Scheffold Veikko Salomaa Domenico Girelli Christopher B Granger Leena Peltonen Pascal P McKeown David Altshuler Olle Melander Joseph M Devaney Stephen E Epstein Daniel J Rader Roberto Elosua James C Engert Sonia S Anand Alistair S Hall Andreas Ziegler Christopher J O'Donnell John A Spertus David Siscovick Stephen M Schwartz Diane Becker Unnur Thorsteinsdottir Kari Stefansson Heribert Schunkert Nilesh J Samani Thomas Quertermous

J Am Coll Cardiol 2010 Nov;56(19):1552-63

Department of Medicine, Stanford University School of Medicine, Stanford, California 94304-1334, USA.

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November 2010

Genome-wide association study identifies a sequence variant within the DAB2IP gene conferring susceptibility to abdominal aortic aneurysm.

Authors:
Solveig Gretarsdottir Annette F Baas Gudmar Thorleifsson Hilma Holm Martin den Heijer Jean-Paul P M de Vries Steef E Kranendonk Clark J A M Zeebregts Steven M van Sterkenburg Robert H Geelkerken Andre M van Rij Michael J A Williams Albert P M Boll Jelena P Kostic Adalbjorg Jonasdottir Aslaug Jonasdottir G Bragi Walters Gisli Masson Patrick Sulem Jona Saemundsdottir Magali Mouy Kristinn P Magnusson Gerard Tromp James R Elmore Natzi Sakalihasan Raymond Limet Jean-Olivier Defraigne Robert E Ferrell Antti Ronkainen Ynte M Ruigrok Cisca Wijmenga Diederick E Grobbee Svati H Shah Christopher B Granger Arshed A Quyyumi Viola Vaccarino Riyaz S Patel A Maziar Zafari Allan I Levey Harland Austin Domenico Girelli Pier Franco Pignatti Oliviero Olivieri Nicola Martinelli Giovanni Malerba Elisabetta Trabetti Lewis C Becker Diane M Becker Muredach P Reilly Daniel J Rader Thomas Mueller Benjamin Dieplinger Meinhard Haltmayer Sigitas Urbonavicius Bengt Lindblad Anders Gottsäter Eleonora Gaetani Roberto Pola Philip Wells Marc Rodger Melissa Forgie Nicole Langlois Javier Corral Vicente Vicente Jordi Fontcuberta Francisco España Niels Grarup Torben Jørgensen Daniel R Witte Torben Hansen Oluf Pedersen Katja K Aben Jacqueline de Graaf Suzanne Holewijn Lasse Folkersen Anders Franco-Cereceda Per Eriksson David A Collier Hreinn Stefansson Valgerdur Steinthorsdottir Thorunn Rafnar Einar M Valdimarsson Hulda B Magnadottir Sigurlaug Sveinbjornsdottir Isleifur Olafsson Magnus Karl Magnusson Robert Palmason Vilhelmina Haraldsdottir Karl Andersen Pall T Onundarson Gudmundur Thorgeirsson Lambertus A Kiemeney Janet T Powell David J Carey Helena Kuivaniemi Jes S Lindholt Gregory T Jones Augustine Kong Jan D Blankensteijn Stefan E Matthiasson Unnur Thorsteinsdottir Kari Stefansson

Nat Genet 2010 Aug 11;42(8):692-7. Epub 2010 Jul 11.

Population Genomics, deCODE Genetics, Reykjavik, Iceland.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4157066PMC
August 2010

Evidence for a role of immunoproteasomes in regulating cardiac muscle mass in diabetic mice.

J Mol Cell Cardiol 2010 Jul 12;49(1):5-15. Epub 2010 Feb 12.

Division of Cardiology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

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http://dx.doi.org/10.1016/j.yjmcc.2010.02.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2883685PMC
July 2010

Effect of obesity on platelet reactivity and response to low-dose aspirin.

Prev Cardiol 2010 ;13(2):56-62

Department of Population Medicine, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1111/j.1751-7141.2009.00058.xDOI Listing
July 2010

Independent metabolic syndrome variants predict new-onset coronary artery disease.

Diabetes Care 2010 Jun 18;33(6):1376-8. Epub 2010 Mar 18.

Department of Medicine, Division of General Internal Medicine, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA.

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http://dx.doi.org/10.2337/dc09-2211DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2875458PMC
June 2010

Avoiding the high Bonferroni penalty in genome-wide association studies.

Genet Epidemiol 2010 Jan;34(1):100-5

Division of Statistical Genomics, Washington University School of Medicine, St. Louis, MO 63108, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2796708PMC
January 2010

Single nucleotide polymorphisms in monocyte chemoattractant protein-1 and its receptor act synergistically to increase the risk of carotid atherosclerosis.

Cerebrovasc Dis 2009 5;28(2):124-30. Epub 2009 Jun 5.

Department of Anesthesiology/Critical Care Medicine, Johns Hopkins School of Medicine, Baltimore, MD 21287, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2914430PMC
September 2009

Ischemic preconditioning-induced cardioprotection is lost in mice with immunoproteasome subunit low molecular mass polypeptide-2 deficiency.

FASEB J 2008 Dec 26;22(12):4248-57. Epub 2008 Aug 26.

Division of Cardiology, Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

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http://www.fasebj.org/doi/10.1096/fj.08-105940
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2614607PMC
December 2008

A novel variant in the platelet endothelial aggregation receptor-1 gene is associated with increased platelet aggregability.

Arterioscler Thromb Vasc Biol 2008 Aug 29;28(8):1484-90. Epub 2008 May 29.

Departments of Medicine and Anesthesiology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA.

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https://www.ahajournals.org/doi/10.1161/ATVBAHA.108.168971
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2739240PMC
August 2008

Sustainability of a multiple risk factor intervention on cardiovascular disease in high-risk African American families.

Ethn Dis 2008 ;18(2):169-75

Division of General Internal Medicine, Johns Hopkins Medical Institutions, Baltimore, Maryland 21287, USA.

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July 2008

Platelet inhibition by aspirin 81 and 325 mg/day in men versus women without clinically apparent cardiovascular disease.

Am J Cardiol 2008 May 17;101(9):1359-63. Epub 2008 Mar 17.

Division of General Internal Medicine, Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

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http://dx.doi.org/10.1016/j.amjcard.2007.12.038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3038606PMC
May 2008

Casual chocolate consumption and inhibition of platelet function.

Prev Cardiol 2007 ;10(4):175-80

Department of Medicine, Division of General Internal Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.

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December 2007

Fractalkine upregulates intercellular adhesion molecule-1 in endothelial cells through CX3CR1 and the Jak Stat5 pathway.

Circ Res 2007 Nov 20;101(10):1001-8. Epub 2007 Sep 20.

Cardiology Division, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

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http://dx.doi.org/10.1161/CIRCRESAHA.107.160812DOI Listing
November 2007

Pharmacogenomics of platelet responsiveness to aspirin.

Pharmacogenomics 2007 Oct;8(10):1413-25

Johns Hopkins University School of Medicine, Department of Anesthesiology/Critical Care Medicine, Division of Cardiac Surgical Intensive Care, 298 Meyer Bldg, 600 N Wolfe St, Baltimore, MD 21287, USA.

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https://www.futuremedicine.com/doi/10.2217/14622416.8.10.141
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October 2007

A monocyte chemoattractant protein-1 gene polymorphism is associated with occult ischemia in a high-risk asymptomatic population.

Atherosclerosis 2007 Aug 24;193(2):366-72. Epub 2006 Aug 24.

Immunopathology Section, National Institute of Dental and Craniofacial Research, USA.

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http://dx.doi.org/10.1016/j.atherosclerosis.2006.06.029DOI Listing
August 2007

Heritability of platelet responsiveness to aspirin in activation pathways directly and indirectly related to cyclooxygenase-1.

Circulation 2007 May 30;115(19):2490-6. Epub 2007 Apr 30.

Department of Anesthesiology/Critical Care Medicine, Division of Cardiac Surgical Intensive Care, Johns Hopkins Medical Institutions, Baltimore, MD, USA.

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https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.106.6
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May 2007

Glucose levels in the normal range predict incident diabetes in families with premature coronary heart disease.

Diabetes Res Clin Pract 2006 Dec 23;74(3):267-73. Epub 2006 May 23.

Divisions of General Internal Medicine, The Johns Hopkins Medical Institutions, Baltimore, MD, USA.

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December 2006

Inhibition of TNF-alpha reduces myocardial injury and proinflammatory pathways following ischemia-reperfusion in the dog.

J Cardiovasc Pharmacol 2006 Dec;48(6):320-8

Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

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December 2006

Impaired chronotropic and vasodilator reserves limit exercise capacity in patients with heart failure and a preserved ejection fraction.

Circulation 2006 Nov 6;114(20):2138-47. Epub 2006 Nov 6.

Division of Cardiology, Department of Medicine, Johns Hopkins Medical Institutions, Baltimore, MD 21205, USA.

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November 2006

Relation between atherosclerosis risk factors and aspirin resistance in a primary prevention population.

Am J Cardiol 2006 Sep 28;98(6):774-9. Epub 2006 Jul 28.

Division of Cardiac Surgical Intensive Care, Department of Anesthesiology/Critical Care Medicine, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA.

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September 2006

Sex differences in platelet reactivity and response to low-dose aspirin therapy.

JAMA 2006 Mar;295(12):1420-7

Division of General Internal Medicine, Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, Md, USA.

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http://jama.jamanetwork.com/article.aspx?doi=10.1001/jama.29
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http://dx.doi.org/10.1001/jama.295.12.1420DOI Listing
March 2006

Comparison of coronary calcium and stress myocardial perfusion imaging in apparently healthy siblings of individuals with premature coronary artery disease.

Am J Cardiol 2006 Feb;97(3):328-33

The Department of Medicine, Division of Cardiology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

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http://dx.doi.org/10.1016/j.amjcard.2005.08.048DOI Listing
February 2006

Interaction of body mass index and framingham risk score in predicting incident coronary disease in families.

Circulation 2005 Apr;111(15):1871-6

Center for Cardiovascular Disease Prevention, Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, 900 Commonwealth Ave East, 3rd Floor, Boston, MA 02215, USA.

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https://www.ahajournals.org/doi/10.1161/01.CIR.0000161956.75
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http://dx.doi.org/10.1161/01.CIR.0000161956.75255.7BDOI Listing
April 2005

Yin and yang of MCP-1.

Authors:
Lewis C Becker

Circ Res 2005 Apr;96(8):812-4

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http://dx.doi.org/10.1161/01.RES.0000165652.82726.d9DOI Listing
April 2005