Levy Kopelovich

Levy Kopelovich

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Levy Kopelovich

Levy Kopelovich

Publications by authors named "Levy Kopelovich"

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Erratum: Drug-Targeted Inhibition of Peroxisome Proliferator-Activated Receptor-gamma Enhances the Chemopreventive Effect of Anti-Estrogen Therapy.

Oncotarget 2018 Sep 18;9(73):33866. Epub 2018 Sep 18.

Department of Oncology, Georgetown University School of Medicine, and Lombardi Comprehensive Cancer Center, Washington, DC.

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http://dx.doi.org/10.18632/oncotarget.26161DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173472PMC
September 2018

PPARs as determinants of the estrogen receptor lineage: use of synthetic lethality for the treatment of estrogen receptor-negative breast cancer.

Oncotarget 2017 Aug 20;8(31):50337-50341. Epub 2017 Apr 20.

Department of Medicine, Weill Cornell College of Medicine, New York, NY, USA.

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http://dx.doi.org/10.18632/oncotarget.17302DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584135PMC
August 2017

Naproxen Inhibits UVB-induced Basal Cell and Squamous Cell Carcinoma Development in Ptch1 /SKH-1 Hairless Mice.

Photochem Photobiol 2017 07 9;93(4):1016-1024. Epub 2017 May 9.

Department of Dermatology, VH509 University of Alabama at Birmingham, Birmingham, AL.

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http://dx.doi.org/10.1111/php.12758DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5784408PMC
July 2017

Targeting cancer stem cells with p53 modulators.

Oncotarget 2016 Jul;7(29):45079-45093

University of Pittsburgh Cancer Institute, Pittsburgh, PA, USA.

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http://dx.doi.org/10.18632/oncotarget.8650DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216707PMC
July 2016

Simultaneous targeting of 5-LOX-COX and ODC block NNK-induced lung adenoma progression to adenocarcinoma in A/J mice.

Am J Cancer Res 2016 1;6(5):894-909. Epub 2016 May 1.

Center for Cancer Prevention and Drug Development, Hematology-Oncology Section, Department of Medicine, Stephenson Cancer Center, University of Oklahoma Health Sciences Center Oklahoma City, OK 73104, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4889708PMC
June 2016

Targeting mTOR and p53 Signaling Inhibits Muscle Invasive Bladder Cancer In Vivo.

Cancer Prev Res (Phila) 2016 Jan 17;9(1):53-62. Epub 2015 Nov 17.

Center for Cancer Prevention and Drug Development, Hem-Onc Section, Department of Medicine, Stephenson Cancer Center, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma.

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http://dx.doi.org/10.1158/1940-6207.CAPR-15-0199DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839263PMC
January 2016

Early and delayed intervention with rapamycin prevents NNK-induced lung adenocarcinoma in A/J mice.

Oncol Rep 2015 Dec 16;34(6):2925-34. Epub 2015 Sep 16.

Center for Chemoprevention and Cancer Drug Development, Department of Medicine, Hem-Onc Section, PCS Oklahoma Cancer Center, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.

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http://dx.doi.org/10.3892/or.2015.4277DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735698PMC
December 2015

TP53 modulating agent, CP-31398 enhances antitumor effects of ODC inhibitor in mouse model of urinary bladder transitional cell carcinoma.

Am J Cancer Res 2015 15;5(10):3030-41. Epub 2015 Sep 15.

Center for Cancer Prevention and Drug Development, Stephenson Cancer Center, Department of Medicine, Hematology-Oncology Section, University of Oklahoma Health Sciences Center Oklahoma City, OK, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4656728PMC
December 2015

Detection of Exosomal miRNAs in the Plasma of Melanoma Patients.

J Clin Med 2015 Dec 17;4(12):2012-27. Epub 2015 Dec 17.

Department of Pathology and Laboratory Medicine, Center for Cancer Research, University of Tennessee Health Science Center, 19 South Manassas Street, Memphis, TN 38163, USA.

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http://dx.doi.org/10.3390/jcm4121957DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693157PMC
December 2015

Small-Molecule NSC59984 Restores p53 Pathway Signaling and Antitumor Effects against Colorectal Cancer via p73 Activation and Degradation of Mutant p53.

Cancer Res 2015 Sep 20;75(18):3842-52. Epub 2015 Aug 20.

Penn State Hershey Cancer Institute, Hershey, Pennsylvania. Laboratory of Translational Oncology and Experimental Cancer Therapeutics, Department of Medical Oncology and Molecular Therapeutics Program, Fox Chase Cancer Center, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1158/0008-5472.CAN-13-1079DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4573895PMC
September 2015

Polymorphisms in alcohol metabolism genes ADH1B and ALDH2, alcohol consumption and colorectal cancer.

PLoS One 2013 25;8(11):e80158. Epub 2013 Nov 25.

Cancer Prevention and Control Program, Catalan Institute of Oncology, Barcelona, Spain ; Colorectal Cancer Group, Bellvitge Biomedical Research Institute and Consorcio de Investigación Biomédica de Epidemiología y Salud Pública (CIBERESP), Barcelona, Spain.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0080158PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3839967PMC
January 2015

Chemoprevention of urothelial cell carcinoma growth and invasion by the dual COX-LOX inhibitor licofelone in UPII-SV40T transgenic mice.

Cancer Prev Res (Phila) 2014 Jul 2;7(7):708-16. Epub 2014 May 2.

Authors' Affiliations: Center for Cancer Prevention and Drug Development, Hem-Onc Section, Department of Medicine, PCS Oklahoma Cancer Center, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma;

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http://dx.doi.org/10.1158/1940-6207.CAPR-14-0087DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4310686PMC
July 2014

p53 modulates Hsp90 ATPase activity and regulates aryl hydrocarbon receptor signaling.

Cancer Prev Res (Phila) 2014 Jun 15;7(6):596-606. Epub 2014 Apr 15.

Authors' Affiliations: Department of Medicine, Weill Cornell Medical College; Department of Basic Sciences, College of Dentistry; and Department of Environmental Medicine, School of Medicine, New York University, New York; Department of Otolaryngology-Head and Neck Surgery, The Johns Hopkins Medical Institutions, Baltimore, Maryland; and Department of Medical and Molecular Genetics, Indiana University Simon Cancer Center, Indiana University School of Medicine, Indianapolis, Indiana

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http://dx.doi.org/10.1158/1940-6207.CAPR-14-0051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4074578PMC
June 2014

p53 protein regulates Hsp90 ATPase activity and thereby Wnt signaling by modulating Aha1 expression.

J Biol Chem 2014 Mar 22;289(10):6513-25. Epub 2014 Jan 22.

From the Department of Medicine, Weill Cornell Medical College, New York, New York 10065.

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http://dx.doi.org/10.1074/jbc.M113.532523DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3945316PMC
March 2014

Prodigiosin rescues deficient p53 signaling and antitumor effects via upregulating p73 and disrupting its interaction with mutant p53.

Cancer Res 2014 Feb 18;74(4):1153-65. Epub 2013 Nov 18.

Authors' Affiliations: Hematology/Oncology Division, Penn State College of Medicine, Penn State Hershey Cancer Institute, Penn State Hershey Medical Center, Hershey, Pennsylvania; and Division of Cancer Prevention, National Cancer Institute, Bethesda, Maryland.

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http://cancerres.aacrjournals.org/content/74/4/1153.full.pdf
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http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
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http://dx.doi.org/10.1158/0008-5472.CAN-13-0955DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4535712PMC
February 2014

Unbiased metabolite profiling indicates that a diminished thymidine pool is the underlying mechanism of colon cancer chemoprevention by alpha-difluoromethylornithine.

Cancer Discov 2013 Sep 14;3(9):1072-81. Epub 2013 Jun 14.

1Departments of Medicine, Genetic Medicine and Cell Biology, and 2Pharmacology, Weill Cornell College of Medicine, New York, New York; and 3Division of Chemoprevention, National Cancer Institute, Frederick, Maryland.

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http://dx.doi.org/10.1158/2159-8290.CD-12-0305DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3770777PMC
September 2013

Dietary polyphenols suppress elevated levels of proinflammatory mediators and aromatase in the mammary gland of obese mice.

Cancer Prev Res (Phila) 2013 Sep 23;6(9):886-97. Epub 2013 Jul 23.

Department of Medicine, Weill Cornell Medical College, 525 East 68th St, Room F-206, New York, New York 10065, USA.

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http://dx.doi.org/10.1158/1940-6207.CAPR-13-0140DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3767430PMC
September 2013

Chemopreventive effects of the p53-modulating agents CP-31398 and Prima-1 in tobacco carcinogen-induced lung tumorigenesis in A/J mice.

Neoplasia 2013 Sep;15(9):1018-27

Center for Cancer Prevention and Drug Development, Hematology-Oncology Section, Department of Medicine, Peggy and Charles Stephenson Cancer Center, University of Oklahoma Health Sciences Center, Oklahoma City, OK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3769881PMC
September 2013

Laccaic acid A is a direct, DNA-competitive inhibitor of DNA methyltransferase 1.

J Biol Chem 2013 Aug 9;288(33):23858-67. Epub 2013 Jul 9.

Department of Biochemistry, Carver College of Medicine, University of Iowa, Iowa City, Iowa 52242, USA.

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http://dx.doi.org/10.1074/jbc.M113.480517DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3745332PMC
August 2013

Heritable one-hit events defining cancer prevention?

Cell Cycle 2013 Aug 29;12(16):2553-7. Epub 2013 Jul 29.

Division of Cancer Prevention, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.

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http://dx.doi.org/10.4161/cc.25690DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3865044PMC
August 2013

PPARδ induces estrogen receptor-positive mammary neoplasia through an inflammatory and metabolic phenotype linked to mTOR activation.

Cancer Res 2013 Jul 27;73(14):4349-61. Epub 2013 Jun 27.

Department of Oncology and Lombardi Comprehensive Cancer Center, Lombardi Comprehensive Cancer Center, Washington, DC 20007, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-13-0322DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3723355PMC
July 2013

Rapamycin targeting mTOR and hedgehog signaling pathways blocks human rhabdomyosarcoma growth in xenograft murine model.

Biochem Biophys Res Commun 2013 Jun 9;435(4):557-61. Epub 2013 May 9.

Division of Hematology & Oncology, Department of Pediatrics, University of Alabama at Birmingham, 1600 7th Avenue South, ACC 414, Birmingham, AL 35233, USA.

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http://dx.doi.org/10.1016/j.bbrc.2013.05.001DOI Listing
June 2013

Nitric oxide-releasing sulindac is a novel skin cancer chemopreventive agent for UVB-induced photocarcinogenesis.

Toxicol Appl Pharmacol 2013 May 27;268(3):249-55. Epub 2012 Dec 27.

Department of Dermatology, University of Alabama at Birmingham, 1530 3rd Avenue South, VH509, Birmingham, AL 35294-0019, USA.

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http://dx.doi.org/10.1016/j.taap.2012.12.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3780591PMC
May 2013

Nitric oxide donor exisulind is an effective inhibitor of murine photocarcinogenesis.

Photochem Photobiol 2012 Sep-Oct;88(5):1141-8. Epub 2012 Feb 24.

Department of Dermatology, University of Alabama at Birmingham, Birmingham, AL, USA.

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http://dx.doi.org/10.1111/j.1751-1097.2012.01093.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3368998PMC
January 2013

Metformin, an antidiabetic agent reduces growth of cutaneous squamous cell carcinoma by targeting mTOR signaling pathway.

Photochem Photobiol 2012 Sep-Oct;88(5):1149-56. Epub 2012 Jun 1.

Department of Dermatology, University of Alabama at Birmingham, Birmingham, AL, USA.

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http://dx.doi.org/10.1111/j.1751-1097.2012.01165.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3476735PMC
January 2013

Vorinostat, an HDAC inhibitor attenuates epidermoid squamous cell carcinoma growth by dampening mTOR signaling pathway in a human xenograft murine model.

Toxicol Appl Pharmacol 2013 Jan 9;266(2):233-44. Epub 2012 Nov 9.

Department of Dermatology and Skin Diseases Research Center, University of Alabama at Birmingham, 1530 3rd Avenue South, VH 509, Birmingham, AL 35294-0019, USA.

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http://dx.doi.org/10.1016/j.taap.2012.11.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3534787PMC
January 2013

Altered transcriptome signature of phenotypically normal skin fibroblasts heterozygous for CDKN2A in familial melanoma: relevance to early intervention.

Oncotarget 2013 Jan;4(1):128-41

Department of Pathology and Laboratory Medicine, and the Center for Cancer Research, University of Tennessee Health Science Center, Memphis, TN, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3702213PMC
http://dx.doi.org/10.18632/oncotarget.786DOI Listing
January 2013

Pharmacokinetics and tissue and tumor exposure of CP-31398, a p53-stabilizing agent, in rats.

Cancer Chemother Pharmacol 2012 May;69(5):1301-6

Chemopreventive Agent Development Research Group, Division of Cancer Prevention, National Cancer Institute, 6130 Executive Blvd., Rm. 2116, Bethesda, MD 20892, USA.

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http://link.springer.com/content/pdf/10.1007/s00280-011-1811
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http://link.springer.com/10.1007/s00280-011-1811-9
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http://dx.doi.org/10.1007/s00280-011-1811-9DOI Listing
May 2012

The chemopreventive effect of mifepristone on mammary tumorigenesis is associated with an anti-invasive and anti-inflammatory gene signature.

Cancer Prev Res (Phila) 2012 May 16;5(5):754-64. Epub 2012 Mar 16.

Department of Oncology, Georgetown University Medical Center, Washington, DC 20007, USA.

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http://dx.doi.org/10.1158/1940-6207.CAPR-11-0526DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3437618PMC
May 2012

Drug-targeted inhibition of peroxisome proliferator-activated receptor-gamma enhances the chemopreventive effect of anti-estrogen therapy.

Oncotarget 2012 Mar;3(3):345-56

Department of Oncology, Georgetown University School of Medicine, and Lombardi Comprehensive Cancer Center, Washington, DC, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3359890PMC
http://dx.doi.org/10.18632/oncotarget.457DOI Listing
March 2012

Stem cell antigen-1 deficiency enhances the chemopreventive effect of peroxisome proliferator-activated receptorγ activation.

Cancer Prev Res (Phila) 2012 Jan 28;5(1):51-60. Epub 2011 Sep 28.

Department of Oncology and Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC 20007, USA..

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http://dx.doi.org/10.1158/1940-6207.CAPR-11-0256DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3252486PMC
January 2012

Pharmacological activation of p53 in cancer cells.

Curr Pharm Des 2011 ;17(6):631-9

Department of Dermatology, The University of Alabama at Birmingham, Volker Hall, Room 509, 1530 3rd Avenue South, Birmingham, Alabama 35294-0019, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3780581PMC
November 2011

Subchronic oral toxicity and metabolite profiling of the p53 stabilizing agent, CP-31398, in rats and dogs.

Toxicology 2011 Nov 16;289(2-3):141-50. Epub 2011 Aug 16.

Life Sciences Group, IIT Research Institute, 10 West 35th Street, Chicago, IL 60616, USA.

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http://dx.doi.org/10.1016/j.tox.2011.08.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3195508PMC
November 2011

Phospho-sulindac (OXT-328) combined with difluoromethylornithine prevents colon cancer in mice.

Cancer Prev Res (Phila) 2011 Jul 4;4(7):1052-60. Epub 2011 Apr 4.

Division of Cancer Prevention, Department of Medicine, Stony Brook University, Stony Brook, NY 11794, USA.

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http://dx.doi.org/10.1158/1940-6207.CAPR-11-0067DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3131469PMC
July 2011

Rapamycin and mTORC1 inhibition in the mouse: skin cancer prevention.

Cancer Prev Res (Phila) 2011 Jul;4(7):957-61

Department of Dermatology, Skin Diseases Research Center and UAB Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, Alabama, USA.

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http://dx.doi.org/10.1158/1940-6207.CAPR-11-0266DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3136877PMC
July 2011

Protein nitration and nitrosylation by NO-donating aspirin in colon cancer cells: Relevance to its mechanism of action.

Exp Cell Res 2011 Jun 22;317(10):1359-67. Epub 2011 Mar 22.

Division of Cancer Prevention, Stony Brook University, HSC, T17-080, Stony Brook, NY 11794-8173, USA.

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http://dx.doi.org/10.1016/j.yexcr.2011.03.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3096692PMC
June 2011

Phospho-ibuprofen (MDC-917) is a novel agent against colon cancer: efficacy, metabolism, and pharmacokinetics in mouse models.

J Pharmacol Exp Ther 2011 Jun 21;337(3):876-86. Epub 2011 Mar 21.

Division of Cancer Prevention, Department of Medicine, Stony Brook University, Stony Brook, NY 11794-8173, USA.

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http://dx.doi.org/10.1124/jpet.111.180224DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3101013PMC
June 2011

Aspirin and low-dose nitric oxide-donating aspirin increase life span in a Lynch syndrome mouse model.

Cancer Prev Res (Phila) 2011 May 24;4(5):684-93. Epub 2011 Mar 24.

Department of Molecular Virology, Immunology & Medical Genetics, Ohio State University, Columbus, OH 43210, USA.

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http://dx.doi.org/10.1158/1940-6207.CAPR-10-0319DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3991477PMC
May 2011

Pathogenesis of nonmelanoma skin cancers in organ transplant recipients.

Arch Biochem Biophys 2011 Apr 11;508(2):159-63. Epub 2011 Jan 11.

Department of Dermatology and Skin Diseases Research Center, University of Alabama at Birmingham, Birmingham, AL 35294-0019, USA.

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http://dx.doi.org/10.1016/j.abb.2011.01.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3063391PMC
April 2011

Mutant proteins as cancer-specific biomarkers.

Proc Natl Acad Sci U S A 2011 Feb 19;108(6):2444-9. Epub 2011 Jan 19.

Ludwig Center for Cancer Genetics and Therapeutics and The Howard Hughes Medical Institute, Johns Hopkins Kimmel Cancer Center, Baltimore, MD21231, USA.

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http://dx.doi.org/10.1073/pnas.1019203108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3038743PMC
February 2011

Resveratrol targets transforming growth factor-β2 signaling to block UV-induced tumor progression.

J Invest Dermatol 2011 Jan 19;131(1):195-202. Epub 2010 Aug 19.

Department of Dermatology, Columbia University Medical Center, Irving Cancer Research Center, New York, New York, USA.

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http://dx.doi.org/10.1038/jid.2010.250DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3153356PMC
January 2011

Phospho-sulindac (OXT-328), a novel sulindac derivative, is safe and effective in colon cancer prevention in mice.

Gastroenterology 2010 Oct 20;139(4):1320-32. Epub 2010 Jun 20.

Division of Cancer Prevention, Department of Medicine, Stony Brook University, Stony Brook, New York 11794-8173, USA.

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http://dx.doi.org/10.1053/j.gastro.2010.06.044DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2949489PMC
October 2010

Enhanced induction of mucin-depleted foci in estrogen receptor {beta} knockout mice.

Cancer Prev Res (Phila) 2010 Sep 17;3(9):1198-204. Epub 2010 Aug 17.

Cancer Biology Division, IIT Research Institute, 10 West 35th Street, Chicago, IL 60616, USA.

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http://dx.doi.org/10.1158/1940-6207.CAPR-10-0044DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2933324PMC
September 2010

Genetic variation in 3-hydroxy-3-methylglutaryl CoA reductase modifies the chemopreventive activity of statins for colorectal cancer.

Cancer Prev Res (Phila) 2010 May 19;3(5):597-603. Epub 2010 Apr 19.

Department of Medicine, Weill Cornell School of Medicine, New York, New York 10021, USA.

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http://dx.doi.org/10.1158/1940-6207.CAPR-10-0007DOI Listing
May 2010

Inhibition of BCL2 expression and activity increases H460 sensitivity to the growth inhibitory effects of polyphenon E.

J Exp Ther Oncol 2009 ;8(2):129-44

Department of Medicine, College of Physicians and Surgeons of Columbia University, 177 Fort Washington Avenue, New York, NY 10032, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361110PMC
March 2010

Sulindac effects on inflammation and tumorigenesis in the intestine of mice with Apc and Mlh1 mutations.

Carcinogenesis 2009 Nov 15;30(11):1923-6. Epub 2009 Sep 15.

Strang Cancer Research Laboratory, Division of Gastroenterology and Hepatology, Department of Medicine, Weill Medical College of Cornell University, New York, NY 10021, USA.

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http://dx.doi.org/10.1093/carcin/bgp200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2783002PMC
November 2009

Inhibition of azoxymethane-induced colorectal cancer by CP-31398, a TP53 modulator, alone or in combination with low doses of celecoxib in male F344 rats.

Cancer Res 2009 Oct 13;69(20):8175-82. Epub 2009 Oct 13.

Department of Medicine, Hem-Onc Section, University of Oklahoma Cancer Institute, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma 73104, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-09-1377DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2792897PMC
October 2009

A Tcf4-GFP reporter mouse model for monitoring effects of Apc mutations during intestinal tumorigenesis.

Mol Carcinog 2009 Sep;48(9):821-31

Thomas Jefferson University, Kimmel Cancer Center, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1002/mc.20526DOI Listing
September 2009

Multiple molecular targets of resveratrol: Anti-carcinogenic mechanisms.

Arch Biochem Biophys 2009 Jun;486(2):95-102

Departments of Dermatology, Columbia University Medical Center, Irving Cancer Research Center, New York, NY 10032, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2749321PMC
June 2009

Identification of microbial DNA in human cancer.

BMC Med Genomics 2009 May 8;2:22. Epub 2009 May 8.

Preston Robert Tisch Brain Tumor Center, Pediatric Brain Tumor Foundation Institute, Department of Pathology, Duke University Medical Center, Durham, North Carolina 27710, USA.

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http://dx.doi.org/10.1186/1755-8794-2-22DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2685141PMC
May 2009

Ovarian adenocarcinomas in the laying hen and women share similar alterations in p53, ras, and HER-2/neu.

Cancer Prev Res (Phila) 2009 Feb 27;2(2):114-21. Epub 2009 Jan 27.

Division of Gynecologic Oncology, Evanston Northwestern Healthcare, Northwestern University, Evanston, Illinois, [corrected] USA.

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http://dx.doi.org/10.1158/1940-6207.CAPR-08-0065DOI Listing
February 2009

Efficacy of chemopreventive agents in mouse mammary gland organ culture (MMOC) model: a comprehensive review.

Curr Med Chem 2008 ;15(27):2785-825

IIT Research Institute, 10 West 35th Street, Chicago, IL 60616, USA.

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January 2009

Inhibition of peroxisome proliferator-activated receptor gamma increases estrogen receptor-dependent tumor specification.

Cancer Res 2009 Jan;69(2):687-94

Department of Oncology and Lombardi Comprehensive Cancer Center, Georgetown University, Washington, District of Columbia 20007, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-08-2446DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3693579PMC
January 2009

Pharmacokinetic and pharmacodynamic study of NO-donating aspirin in F344 rats.

Int J Oncol 2008 Oct;33(4):799-805

Department of Medicine, Hematology-Oncology Section, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2579329PMC
October 2008

Suppression of familial adenomatous polyposis by CP-31398, a TP53 modulator, in APCmin/+ mice.

Cancer Res 2008 Sep;68(18):7670-5

Department of Medicine, Hem-Onc Section, University of Oklahoma Cancer Institute, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma 73104, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-08-1610DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2597360PMC
September 2008

Cyclooxygenase-2 inhibitor nimesulide blocks ultraviolet B-induced photocarcinogenesis in SKH-1 hairless mice.

Photochem Photobiol 2008 Mar-Apr;84(2):522-7. Epub 2008 Feb 2.

Department of Dermatology, College of Physicians and Surgeons, Columbia University, New York, NY, USA.

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http://dx.doi.org/10.1111/j.1751-1097.2008.00303.xDOI Listing
April 2008

A forward chemical genetic screen reveals an inhibitor of the Mre11-Rad50-Nbs1 complex.

Nat Chem Biol 2008 Feb 6;4(2):119-25. Epub 2008 Jan 6.

Columbia University, Institute for Cancer Genetics, Irving Cancer Research Center, 1130 St. Nicholas Avenue, Room 602, New York, New York 10032, USA.

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http://dx.doi.org/10.1038/nchembio.63DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3065498PMC
February 2008

CP-31398 restores mutant p53 tumor suppressor function and inhibits UVB-induced skin carcinogenesis in mice.

J Clin Invest 2007 Dec;117(12):3753-64

Department of Dermatology, Columbia University College of Physicians and Surgeons, New York, New York, USA.

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http://dx.doi.org/10.1172/JCI32481DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2096455PMC
December 2007

Nitric oxide-donating aspirin derivatives suppress microsatellite instability in mismatch repair-deficient and hereditary nonpolyposis colorectal cancer cells.

Cancer Res 2007 Nov;67(22):10966-75

Department of Molecular Virology, Immunology, and Medical Genetics, The Ohio State University Comprehensive Cancer Center and Medical Center, Columbus, Ohio 43026, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-07-2562DOI Listing
November 2007

The inhibitory effect of (-)-epigallocatechin gallate on activation of the epidermal growth factor receptor is associated with altered lipid order in HT29 colon cancer cells.

Cancer Res 2007 Jul;67(13):6493-501

Herbert Irving Comprehensive Cancer Center and Department of Medicine, Columbia University Medical Center, New Yourk, NY 10032-2704, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-07-0411DOI Listing
July 2007

The mammalian target of rapamycin pathway as a potential target for cancer chemoprevention.

Cancer Epidemiol Biomarkers Prev 2007 Jul;16(7):1330-40

Division of Cancer Prevention, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.

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http://cebp.aacrjournals.org/cgi/doi/10.1158/1055-9965.EPI-0
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http://dx.doi.org/10.1158/1055-9965.EPI-07-0045DOI Listing
July 2007