Publications by authors named "Levon M Khachigian"

100Publications

Recruitment and maturation of the coronary collateral circulation: Current understanding and perspectives in arteriogenesis.

Microvasc Res 2020 Nov 13;132:104058. Epub 2020 Aug 13.

Department of Cardiology, Royal North Shore Hospital, Sydney, Australia; The University of Sydney, Sydney, Australia.

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http://dx.doi.org/10.1016/j.mvr.2020.104058DOI Listing
November 2020

Pharmaceutical patents: reconciling the human right to health with the incentive to invent.

Drug Discov Today 2020 Jul 20;25(7):1135-1141. Epub 2020 Apr 20.

Vascular Biology and Translational Research, School of Medical Sciences, Faculty of Medicine, University of New South Wales, Sydney NSW 2052, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.drudis.2020.04.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7169928PMC
July 2020

Remote Ischemic Preconditioning induces Cardioprotective Autophagy and Signals through the IL-6-Dependent JAK-STAT Pathway.

Int J Mol Sci 2020 Mar 1;21(5). Epub 2020 Mar 1.

Department of Cardiology, Kolling Institute of Medical Research, Northern Sydney Local Health District, St Leonards, NSW 2065, Australia.

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http://dx.doi.org/10.3390/ijms21051692DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7084188PMC
March 2020

Repurposing drugs for skin cancer.

Curr Med Chem 2019 Dec 19. Epub 2019 Dec 19.

Vascular Biology and Translational Research, School of Medical Sciences, Faculty of Medicine, University of New South Wales,Sydney NSW 2052. Australia.

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http://dx.doi.org/10.2174/0929867327666191220103901DOI Listing
December 2019

Transcription Factors Targeted by miRNAs Regulating Smooth Muscle Cell Growth and Intimal Thickening after Vascular Injury.

Int J Mol Sci 2019 Oct 31;20(21). Epub 2019 Oct 31.

Vascular Biology and Translational Research, School of Medical Sciences, Faculty of Medicine, University of New South Wales, Sydney NSW 2052, Australia.

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http://dx.doi.org/10.3390/ijms20215445DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6861964PMC
October 2019

The anthelmintic flubendazole blocks human melanoma growth and metastasis and suppresses programmed cell death protein-1 and myeloid-derived suppressor cell accumulation.

Cancer Lett 2019 09 23;459:268-276. Epub 2019 May 23.

Vascular Biology and Translational Research, School of Medical Sciences, UNSW Medicine, University of New South Wales, Sydney, NSW, 2052, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2019.05.026DOI Listing
September 2019

Deoxyribozymes as Catalytic Nanotherapeutic Agents.

Cancer Res 2019 03 13;79(5):879-888. Epub 2019 Feb 13.

Vascular Biology and Translational Research, School of Medical Sciences, Faculty of Medicine, University of New South Wales, Sydney, Australia.

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http://dx.doi.org/10.1158/0008-5472.CAN-18-2474DOI Listing
March 2019

Extracellular signal-regulated kinase-1 phosphorylates early growth response-1 at serine 26.

Biochem Biophys Res Commun 2019 03 31;510(3):345-351. Epub 2019 Jan 31.

Vascular Biology and Translational Research Laboratory, School of Medical Sciences, University of New South Wales, Sydney, Australia; UNSW Medicine, University of New South Wales, Sydney, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2019.01.019DOI Listing
March 2019

Promoter Usage and Dynamics in Vascular Smooth Muscle Cells Exposed to Fibroblast Growth Factor-2 or Interleukin-1β.

Sci Rep 2018 09 3;8(1):13164. Epub 2018 Sep 3.

Vascular Biology and Translational Research, School of Medical Sciences, University of New South Wales, Sydney, 2052, Australia.

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http://dx.doi.org/10.1038/s41598-018-30702-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120868PMC
September 2018

Melanoma protective antitumor immunity activated by catalytic DNA.

Oncogene 2018 09 29;37(37):5115-5126. Epub 2018 May 29.

Vascular Biology and Translational Research, School of Medical Sciences & UNSW Medicine, The University of New South Wales, Sydney, NSW, 2052, Australia.

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http://www.nature.com/articles/s41388-018-0306-0
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http://dx.doi.org/10.1038/s41388-018-0306-0DOI Listing
September 2018

Targeted therapies in the management of locally advanced and metastatic pancreatic cancer: a systematic review.

Oncotarget 2018 Apr 20;9(30):21613-21627. Epub 2018 Apr 20.

Vascular Biology and Translational Research, School of Medical Sciences, University of New South Wales, Sydney NSW 2052, Australia.

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http://dx.doi.org/10.18632/oncotarget.25085DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940404PMC
April 2018

The Yin and Yang of YY1 in tumor growth and suppression.

Int J Cancer 2018 08 31;143(3):460-465. Epub 2018 Jan 31.

Vascular Biology and Translational Research, School of Medical Sciences, The University of New South Wales, Sydney, New South Wales, 2052, Australia.

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http://dx.doi.org/10.1002/ijc.31255DOI Listing
August 2018

FANTOM5 CAGE profiles of human and mouse samples.

Authors:
Shuhei Noguchi Takahiro Arakawa Shiro Fukuda Masaaki Furuno Akira Hasegawa Fumi Hori Sachi Ishikawa-Kato Kaoru Kaida Ai Kaiho Mutsumi Kanamori-Katayama Tsugumi Kawashima Miki Kojima Atsutaka Kubosaki Ri-Ichiroh Manabe Mitsuyoshi Murata Sayaka Nagao-Sato Kenichi Nakazato Noriko Ninomiya Hiromi Nishiyori-Sueki Shohei Noma Eri Saijyo Akiko Saka Mizuho Sakai Christophe Simon Naoko Suzuki Michihira Tagami Shoko Watanabe Shigehiro Yoshida Peter Arner Richard A Axton Magda Babina J Kenneth Baillie Timothy C Barnett Anthony G Beckhouse Antje Blumenthal Beatrice Bodega Alessandro Bonetti James Briggs Frank Brombacher Ailsa J Carlisle Hans C Clevers Carrie A Davis Michael Detmar Taeko Dohi Albert S B Edge Matthias Edinger Anna Ehrlund Karl Ekwall Mitsuhiro Endoh Hideki Enomoto Afsaneh Eslami Michela Fagiolini Lynsey Fairbairn Mary C Farach-Carson Geoffrey J Faulkner Carmelo Ferrai Malcolm E Fisher Lesley M Forrester Rie Fujita Jun-Ichi Furusawa Teunis B Geijtenbeek Thomas Gingeras Daniel Goldowitz Sven Guhl Reto Guler Stefano Gustincich Thomas J Ha Masahide Hamaguchi Mitsuko Hara Yuki Hasegawa Meenhard Herlyn Peter Heutink Kelly J Hitchens David A Hume Tomokatsu Ikawa Yuri Ishizu Chieko Kai Hiroshi Kawamoto Yuki I Kawamura Judith S Kempfle Tony J Kenna Juha Kere Levon M Khachigian Toshio Kitamura Sarah Klein S Peter Klinken Alan J Knox Soichi Kojima Haruhiko Koseki Shigeo Koyasu Weonju Lee Andreas Lennartsson Alan Mackay-Sim Niklas Mejhert Yosuke Mizuno Hiromasa Morikawa Mitsuru Morimoto Kazuyo Moro Kelly J Morris Hozumi Motohashi Christine L Mummery Yutaka Nakachi Fumio Nakahara Toshiyuki Nakamura Yukio Nakamura Tadasuke Nozaki Soichi Ogishima Naganari Ohkura Hiroshi Ohno Mitsuhiro Ohshima Mariko Okada-Hatakeyama Yasushi Okazaki Valerio Orlando Dmitry A Ovchinnikov Robert Passier Margaret Patrikakis Ana Pombo Swati Pradhan-Bhatt Xian-Yang Qin Michael Rehli Patrizia Rizzu Sugata Roy Antti Sajantila Shimon Sakaguchi Hiroki Sato Hironori Satoh Suzana Savvi Alka Saxena Christian Schmidl Claudio Schneider Gundula G Schulze-Tanzil Anita Schwegmann Guojun Sheng Jay W Shin Daisuke Sugiyama Takaaki Sugiyama Kim M Summers Naoko Takahashi Jun Takai Hiroshi Tanaka Hideki Tatsukawa Andru Tomoiu Hiroo Toyoda Marc van de Wetering Linda M van den Berg Roberto Verardo Dipti Vijayan Christine A Wells Louise N Winteringham Ernst Wolvetang Yoko Yamaguchi Masayuki Yamamoto Chiyo Yanagi-Mizuochi Misako Yoneda Yohei Yonekura Peter G Zhang Silvia Zucchelli Imad Abugessaisa Erik Arner Jayson Harshbarger Atsushi Kondo Timo Lassmann Marina Lizio Serkan Sahin Thierry Sengstag Jessica Severin Hisashi Shimoji Masanori Suzuki Harukazu Suzuki Jun Kawai Naoto Kondo Masayoshi Itoh Carsten O Daub Takeya Kasukawa Hideya Kawaji Piero Carninci Alistair R R Forrest Yoshihide Hayashizaki

Sci Data 2017 08 29;4:170112. Epub 2017 Aug 29.

RIKEN Omics Science Center, Yokohama, Kanagawa 230-0045, Japan.

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http://dx.doi.org/10.1038/sdata.2017.112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574368PMC
August 2017

Inhibition of intimal thickening after vascular injury with a cocktail of vascular endothelial growth factor and cyclic Arg-Gly-Asp peptide.

Int J Cardiol 2016 Oct 30;220:185-91. Epub 2016 Jun 30.

School of Medical Sciences, University of New South Wales, Sydney, NSW 2052, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.ijcard.2016.06.300DOI Listing
October 2016

Early growth response-1 in the pathogenesis of cardiovascular disease.

J Mol Med (Berl) 2016 07 1;94(7):747-53. Epub 2016 Jun 1.

School of Medical Sciences, Faculty of Medicine, University of New South Wales, Sydney, Australia.

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http://link.springer.com/10.1007/s00109-016-1428-x
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http://dx.doi.org/10.1007/s00109-016-1428-xDOI Listing
July 2016

MicroRNA miR-191 targets the zinc finger transcription factor Egr-1 and suppresses intimal thickening after carotid injury.

Int J Cardiol 2016 Jun 16;212:299-302. Epub 2016 Mar 16.

School of Medical Sciences, University of New South Wales, Sydney, NSW 2052, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.ijcard.2016.03.037DOI Listing
June 2016

Transcribed enhancers lead waves of coordinated transcription in transitioning mammalian cells.

Authors:
Erik Arner Carsten O Daub Kristoffer Vitting-Seerup Robin Andersson Berit Lilje Finn Drabløs Andreas Lennartsson Michelle Rönnerblad Olga Hrydziuszko Morana Vitezic Tom C Freeman Ahmad M N Alhendi Peter Arner Richard Axton J Kenneth Baillie Anthony Beckhouse Beatrice Bodega James Briggs Frank Brombacher Margaret Davis Michael Detmar Anna Ehrlund Mitsuhiro Endoh Afsaneh Eslami Michela Fagiolini Lynsey Fairbairn Geoffrey J Faulkner Carmelo Ferrai Malcolm E Fisher Lesley Forrester Daniel Goldowitz Reto Guler Thomas Ha Mitsuko Hara Meenhard Herlyn Tomokatsu Ikawa Chieko Kai Hiroshi Kawamoto Levon M Khachigian S Peter Klinken Soichi Kojima Haruhiko Koseki Sarah Klein Niklas Mejhert Ken Miyaguchi Yosuke Mizuno Mitsuru Morimoto Kelly J Morris Christine Mummery Yutaka Nakachi Soichi Ogishima Mariko Okada-Hatakeyama Yasushi Okazaki Valerio Orlando Dmitry Ovchinnikov Robert Passier Margaret Patrikakis Ana Pombo Xian-Yang Qin Sugata Roy Hiroki Sato Suzana Savvi Alka Saxena Anita Schwegmann Daisuke Sugiyama Rolf Swoboda Hiroshi Tanaka Andru Tomoiu Louise N Winteringham Ernst Wolvetang Chiyo Yanagi-Mizuochi Misako Yoneda Susan Zabierowski Peter Zhang Imad Abugessaisa Nicolas Bertin Alexander D Diehl Shiro Fukuda Masaaki Furuno Jayson Harshbarger Akira Hasegawa Fumi Hori Sachi Ishikawa-Kato Yuri Ishizu Masayoshi Itoh Tsugumi Kawashima Miki Kojima Naoto Kondo Marina Lizio Terrence F Meehan Christopher J Mungall Mitsuyoshi Murata Hiromi Nishiyori-Sueki Serkan Sahin Sayaka Nagao-Sato Jessica Severin Michiel J L de Hoon Jun Kawai Takeya Kasukawa Timo Lassmann Harukazu Suzuki Hideya Kawaji Kim M Summers Christine Wells David A Hume Alistair R R Forrest Albin Sandelin Piero Carninci Yoshihide Hayashizaki

Science 2015 Feb 12;347(6225):1010-4. Epub 2015 Feb 12.

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http://dx.doi.org/10.1126/science.1259418DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4681433PMC
February 2015

Regulatory roles of c-jun in H5N1 influenza virus replication and host inflammation.

Biochim Biophys Acta 2014 Dec 26;1842(12 Pt A):2479-88. Epub 2014 Apr 26.

Key Laboratory of Animal Epidemiology and Zoonosis of Ministry of Agriculture, College of Veterinary Medicine, China Agricultural University, Beijing 100193, China; Key Laboratory of Veterinary Bioproduction and Veterinary Medicine of the Ministry of Agriculture, Zhongmu Institute of China Animal Husbandry Industry Co., Ltd, No. 156 Beiqing Road, Haidian District, Beijing 100095, China. Electronic address:

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http://dx.doi.org/10.1016/j.bbadis.2014.04.017DOI Listing
December 2014

A promoter-level mammalian expression atlas.

Authors:
Alistair R R Forrest Hideya Kawaji Michael Rehli J Kenneth Baillie Michiel J L de Hoon Vanja Haberle Timo Lassmann Ivan V Kulakovskiy Marina Lizio Masayoshi Itoh Robin Andersson Christopher J Mungall Terrence F Meehan Sebastian Schmeier Nicolas Bertin Mette Jørgensen Emmanuel Dimont Erik Arner Christian Schmidl Ulf Schaefer Yulia A Medvedeva Charles Plessy Morana Vitezic Jessica Severin Colin A Semple Yuri Ishizu Robert S Young Margherita Francescatto Intikhab Alam Davide Albanese Gabriel M Altschuler Takahiro Arakawa John A C Archer Peter Arner Magda Babina Sarah Rennie Piotr J Balwierz Anthony G Beckhouse Swati Pradhan-Bhatt Judith A Blake Antje Blumenthal Beatrice Bodega Alessandro Bonetti James Briggs Frank Brombacher A Maxwell Burroughs Andrea Califano Carlo V Cannistraci Daniel Carbajo Yun Chen Marco Chierici Yari Ciani Hans C Clevers Emiliano Dalla Carrie A Davis Michael Detmar Alexander D Diehl Taeko Dohi Finn Drabløs Albert S B Edge Matthias Edinger Karl Ekwall Mitsuhiro Endoh Hideki Enomoto Michela Fagiolini Lynsey Fairbairn Hai Fang Mary C Farach-Carson Geoffrey J Faulkner Alexander V Favorov Malcolm E Fisher Martin C Frith Rie Fujita Shiro Fukuda Cesare Furlanello Masaaki Furino Jun-ichi Furusawa Teunis B Geijtenbeek Andrew P Gibson Thomas Gingeras Daniel Goldowitz Julian Gough Sven Guhl Reto Guler Stefano Gustincich Thomas J Ha Masahide Hamaguchi Mitsuko Hara Matthias Harbers Jayson Harshbarger Akira Hasegawa Yuki Hasegawa Takehiro Hashimoto Meenhard Herlyn Kelly J Hitchens Shannan J Ho Sui Oliver M Hofmann Ilka Hoof Furni Hori Lukasz Huminiecki Kei Iida Tomokatsu Ikawa Boris R Jankovic Hui Jia Anagha Joshi Giuseppe Jurman Bogumil Kaczkowski Chieko Kai Kaoru Kaida Ai Kaiho Kazuhiro Kajiyama Mutsumi Kanamori-Katayama Artem S Kasianov Takeya Kasukawa Shintaro Katayama Sachi Kato Shuji Kawaguchi Hiroshi Kawamoto Yuki I Kawamura Tsugumi Kawashima Judith S Kempfle Tony J Kenna Juha Kere Levon M Khachigian Toshio Kitamura S Peter Klinken Alan J Knox Miki Kojima Soichi Kojima Naoto Kondo Haruhiko Koseki Shigeo Koyasu Sarah Krampitz Atsutaka Kubosaki Andrew T Kwon Jeroen F J Laros Weonju Lee Andreas Lennartsson Kang Li Berit Lilje Leonard Lipovich Alan Mackay-Sim Ri-ichiroh Manabe Jessica C Mar Benoit Marchand Anthony Mathelier Niklas Mejhert Alison Meynert Yosuke Mizuno David A de Lima Morais Hiromasa Morikawa Mitsuru Morimoto Kazuyo Moro Efthymios Motakis Hozumi Motohashi Christine L Mummery Mitsuyoshi Murata Sayaka Nagao-Sato Yutaka Nakachi Fumio Nakahara Toshiyuki Nakamura Yukio Nakamura Kenichi Nakazato Erik van Nimwegen Noriko Ninomiya Hiromi Nishiyori Shohei Noma Shohei Noma Tadasuke Noazaki Soichi Ogishima Naganari Ohkura Hiroko Ohimiya Hiroshi Ohno Mitsuhiro Ohshima Mariko Okada-Hatakeyama Yasushi Okazaki Valerio Orlando Dmitry A Ovchinnikov Arnab Pain Robert Passier Margaret Patrikakis Helena Persson Silvano Piazza James G D Prendergast Owen J L Rackham Jordan A Ramilowski Mamoon Rashid Timothy Ravasi Patrizia Rizzu Marco Roncador Sugata Roy Morten B Rye Eri Saijyo Antti Sajantila Akiko Saka Shimon Sakaguchi Mizuho Sakai Hiroki Sato Suzana Savvi Alka Saxena Claudio Schneider Erik A Schultes Gundula G Schulze-Tanzil Anita Schwegmann Thierry Sengstag Guojun Sheng Hisashi Shimoji Yishai Shimoni Jay W Shin Christophe Simon Daisuke Sugiyama Takaai Sugiyama Masanori Suzuki Naoko Suzuki Rolf K Swoboda Peter A C 't Hoen Michihira Tagami Naoko Takahashi Jun Takai Hiroshi Tanaka Hideki Tatsukawa Zuotian Tatum Mark Thompson Hiroo Toyodo Tetsuro Toyoda Elvind Valen Marc van de Wetering Linda M van den Berg Roberto Verado Dipti Vijayan Ilya E Vorontsov Wyeth W Wasserman Shoko Watanabe Christine A Wells Louise N Winteringham Ernst Wolvetang Emily J Wood Yoko Yamaguchi Masayuki Yamamoto Misako Yoneda Yohei Yonekura Shigehiro Yoshida Susan E Zabierowski Peter G Zhang Xiaobei Zhao Silvia Zucchelli Kim M Summers Harukazu Suzuki Carsten O Daub Jun Kawai Peter Heutink Winston Hide Tom C Freeman Boris Lenhard Vladimir B Bajic Martin S Taylor Vsevolod J Makeev Albin Sandelin David A Hume Piero Carninci Yoshihide Hayashizaki

Nature 2014 Mar;507(7493):462-70

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http://dx.doi.org/10.1038/nature13182DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4529748PMC
March 2014

DNAzyme delivery approaches in biological settings.

Curr Med Chem 2013 ;20(28):3448-55

Centre for Vascular Research, University of New South Wales, Sydney, NSW 2052, Australia.

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http://dx.doi.org/10.2174/09298673113209990033DOI Listing
February 2014

GILZ overexpression inhibits endothelial cell adhesive function through regulation of NF-κB and MAPK activity.

J Immunol 2013 Jul 31;191(1):424-33. Epub 2013 May 31.

Centre for Inflammatory Diseases, Monash University Department of Medicine, Monash Medical Centre, Clayton, Victoria 3168, Australia.

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http://dx.doi.org/10.4049/jimmunol.1202662DOI Listing
July 2013

Therapeutic perspectives on pancreatic cancer.

Curr Cancer Drug Targets 2013 May;13(4):400-10

Centre for Vascular Research, School of Medical Sciences, University of New South Wales, Sydney, Australia.

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http://dx.doi.org/10.2174/1568009611313040004DOI Listing
May 2013

Current and potential treatments for cervical cancer.

Curr Cancer Drug Targets 2013 Feb;13(2):205-20

Centre for Vascular Research, University of New South Wales, Sydney, NSW 2052, Australia.

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http://dx.doi.org/10.2174/1568009611313020009DOI Listing
February 2013

SUMOylation regulates the transcriptional repression activity of FOG-2 and its association with GATA-4.

PLoS One 2012 30;7(11):e50637. Epub 2012 Nov 30.

Department of Medicine, St George Clinical School, University of New South Wales, Sydney, New South Wales, Australia.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0050637PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3511347PMC
May 2013

Genistein inhibits PDGF-stimulated proteoglycan synthesis in vascular smooth muscle without blocking PDGFβ receptor phosphorylation.

Arch Biochem Biophys 2012 Sep 7;525(1):25-31. Epub 2012 Jun 7.

Discipline of Pharmacy, School of Medical Sciences and Diabetes Complications Group, Health Innovations Research Institute, RMIT University, Bundoora, VIC 3083, Australia.

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https://linkinghub.elsevier.com/retrieve/pii/S00039861120023
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http://dx.doi.org/10.1016/j.abb.2012.05.025DOI Listing
September 2012

Platelet-derived growth factor-BB mediates cell migration through induction of activating transcription factor 4 and tenascin-C.

Am J Pathol 2012 Jun 14;180(6):2590-7. Epub 2012 Apr 14.

Centre for Vascular Research, University of New South Wales, Sydney, Australia.

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http://dx.doi.org/10.1016/j.ajpath.2012.02.009DOI Listing
June 2012

Sp1, acetylated histone-3 and p300 regulate TRAIL transcription: mechanisms of PDGF-BB-mediated VSMC proliferation and migration.

J Cell Biochem 2012 Aug;113(8):2597-606

Centre for Vascular Research, University of New South Wales, Sydney, NSW 2052, Australia.

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http://doi.wiley.com/10.1002/jcb.24135
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http://dx.doi.org/10.1002/jcb.24135DOI Listing
August 2012

Intracoronary delivery of DNAzymes targeting human EGR-1 reduces infarct size following myocardial ischaemia reperfusion.

J Pathol 2012 Jun 17;227(2):157-64. Epub 2012 Feb 17.

Centre for Vascular Research, University of New South Wales, Sydney, NSW 2052, Australia.

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http://dx.doi.org/10.1002/path.2991DOI Listing
June 2012

Repression of PDGF-R-α after cellular injury involves TNF-α, formation of a c-Fos-YY1 complex, and negative regulation by HDAC.

Am J Physiol Cell Physiol 2012 Jun 8;302(11):C1590-8. Epub 2012 Feb 8.

Centre for Vascular Research, University of New South Wales, Sydney, Australia.

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http://dx.doi.org/10.1152/ajpcell.00429.2011DOI Listing
June 2012

Yin Yang-1 inhibits tumor cell growth and inhibits p21WAF1/Cip1 complex formation with cdk4 and cyclin D1.

Int J Oncol 2012 May 9;40(5):1575-80. Epub 2012 Feb 9.

Centre for Vascular Research, University of New South Wales, Sydney, Australia.

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http://www.spandidos-publications.com/10.3892/ijo.2012.1362
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http://dx.doi.org/10.3892/ijo.2012.1362DOI Listing
May 2012

Dominantly inherited constitutional epigenetic silencing of MLH1 in a cancer-affected family is linked to a single nucleotide variant within the 5'UTR.

Cancer Cell 2011 Aug;20(2):200-13

Adult Cancer Program, Lowy Cancer Research Centre, Prince of Wales Clinical School, Faculty of Medicine at the University of New South Wales, NSW 2052, Australia.

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http://dx.doi.org/10.1016/j.ccr.2011.07.003DOI Listing
August 2011

Recent developments in drug-eluting stents.

J Mol Med (Berl) 2011 Jun 29;89(6):545-53. Epub 2011 Jan 29.

Centre for Vascular Research, University of New South Wales, Sydney, Australia.

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http://dx.doi.org/10.1007/s00109-011-0729-3DOI Listing
June 2011

Emerging therapeutic approaches in the management of retinal angiogenesis and edema.

J Mol Med (Berl) 2011 Apr 18;89(4):343-61. Epub 2010 Dec 18.

Centre for Vascular Research, University of New South Wales, 3rd floor, Lowy Cancer Research Centre, Sydney, NSW 2052, Australia.

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http://dx.doi.org/10.1007/s00109-010-0709-zDOI Listing
April 2011

Divergent roles of NF-κB and Egr-1 in flow-dependent restenosis after angioplasty and stenting.

Atherosclerosis 2011 Jan 8;214(1):65-72. Epub 2010 Oct 8.

Department of Cardiology, Royal North Shore Hospital and University of Sydney, St Leonards, NSW 2065, Australia.

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http://dx.doi.org/10.1016/j.atherosclerosis.2010.10.003DOI Listing
January 2011

Interplay between heme oxygenase-1 and the multifunctional transcription factor yin yang 1 in the inhibition of intimal hyperplasia.

Circ Res 2010 Dec 28;107(12):1490-7. Epub 2010 Oct 28.

Centre for Vascular Research, School of Medical Sciences and Bosch Institute, Medical Foundation Building (K25), University of Sydney, 92-94 Parramatta Rd, Camperdown, NSW 2006, Australia.

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http://dx.doi.org/10.1161/CIRCRESAHA.110.231985DOI Listing
December 2010

PDGF beta-receptor kinase activity and ERK1/2 mediate glycosaminoglycan elongation on biglycan and increases binding to LDL.

Endocrinology 2010 Sep 7;151(9):4356-67. Epub 2010 Jul 7.

Diabetes and Cell Biology Laboratory, Baker IDI Heart and Diabetes Institute, PO Box 6492, St. Kilda Road Central, Melbourne, Victoria 8008, Australia.

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https://academic.oup.com/endo/article-lookup/doi/10.1210/en.
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http://dx.doi.org/10.1210/en.2010-0027DOI Listing
September 2010

Macrophage migration inhibitory factor increases leukocyte-endothelial interactions in human endothelial cells via promotion of expression of adhesion molecules.

J Immunol 2010 Jul 16;185(2):1238-47. Epub 2010 Jun 16.

Department of Medicine, Monash Medical Centre, Centre for Inflammatory Diseases, Monash University, Clayton, Victoria, Australia.

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http://www.jimmunol.org/cgi/doi/10.4049/jimmunol.0904104
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http://dx.doi.org/10.4049/jimmunol.0904104DOI Listing
July 2010

Activation transcription factor-4 and the acute vascular response to injury.

J Mol Med (Berl) 2010 Jun 21;88(6):545-52. Epub 2010 Mar 21.

Centre for Vascular Research, University of New South Wales, Sydney, NSW, 2052, Australia.

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http://dx.doi.org/10.1007/s00109-010-0615-4DOI Listing
June 2010

TRAIL promotes VSMC proliferation and neointima formation in a FGF-2-, Sp1 phosphorylation-, and NFkappaB-dependent manner.

Circ Res 2010 Apr 11;106(6):1061-71. Epub 2010 Feb 11.

Centre for Vascular Research, The University of New South Wales, Sydney NSW 2052, Australia.

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https://www.ahajournals.org/doi/10.1161/CIRCRESAHA.109.20602
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http://dx.doi.org/10.1161/CIRCRESAHA.109.206029DOI Listing
April 2010

Phosphorylation and acetylation of histone H3 and autoregulation by early growth response 1 mediate interleukin 1beta induction of early growth response 1 transcription.

Arterioscler Thromb Vasc Biol 2010 Mar 17;30(3):536-45. Epub 2009 Dec 17.

Centre for Vascular Research, University of New South Wales, Sydney NSW 2052, Australia.

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http://dx.doi.org/10.1161/ATVBAHA.109.193821DOI Listing
March 2010

Angiotensin II-inducible smooth muscle cell apoptosis involves the angiotensin II type 2 receptor, GATA-6 activation, and FasL-Fas engagement.

Circ Res 2009 Aug 23;105(5):422-30. Epub 2009 Jul 23.

Centre for Vascular Research, University of New South Wales, Sydney NSW 2052, Australia.

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http://dx.doi.org/10.1161/CIRCRESAHA.109.203323DOI Listing
August 2009

c-Jun DNAzymes inhibit myocardial inflammation, ROS generation, infarct size, and improve cardiac function after ischemia-reperfusion injury.

Arterioscler Thromb Vasc Biol 2009 Nov 10;29(11):1836-42. Epub 2009 Jul 10.

Centre for Vascular Research, University of New South Wales, Sydney, NSW, Australia.

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http://dx.doi.org/10.1161/ATVBAHA.109.189753DOI Listing
November 2009

Recent advances in vascular biology: selected highlights from IVBM 2008.

Thromb Haemost 2009 Jun;101(6):997-8

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June 2009

A key role for early growth response-1 and nuclear factor-kappaB in mediating and maintaining GRO/CXCR2 proliferative signaling in esophageal cancer.

Mol Cancer Res 2009 May 12;7(5):755-64. Epub 2009 May 12.

Division of Medical Biochemistry, Institute of Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Anzio Road, Observatory, Cape Town 7925, South Africa.

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http://dx.doi.org/10.1158/1541-7786.MCR-08-0472DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6944287PMC
May 2009

Related transcriptional enhancer factor-1 induces fibroblast growth factor receptor-1 expression in endothelial cells.

Biochem Biophys Res Commun 2009 Mar 29;380(3):689-94. Epub 2009 Jan 29.

Harbin Medical University, Baojian Road, Harbin, Heilongjiang 150081, China.

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http://dx.doi.org/10.1016/j.bbrc.2009.01.151DOI Listing
March 2009

Sp1 phosphorylation and its regulation of gene transcription.

Mol Cell Biol 2009 May 9;29(10):2483-8. Epub 2009 Mar 9.

Centre for Vascular Research, Department of Pathology, University of New South Wales. Sydney, NSW 2052, Australia.

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http://mcb.asm.org/cgi/doi/10.1128/MCB.01828-08
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http://dx.doi.org/10.1128/MCB.01828-08DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2682032PMC
May 2009

Early growth response-1 regulates angiopoietin-1-induced endothelial cell proliferation, migration, and differentiation.

Arterioscler Thromb Vasc Biol 2009 Feb 26;29(2):209-16. Epub 2008 Dec 26.

Critical Care Division, Department of Medicine, McGill University Health Centre, McGill University, Montreal, Québec, Canada.

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http://dx.doi.org/10.1161/ATVBAHA.108.181073DOI Listing
February 2009

c-Jun Is critical for the progression of osteosarcoma: proof in an orthotopic spontaneously metastasizing model.

Mol Cancer Res 2008 Aug;6(8):1289-92

Department of Orthopaedics, St. Vincent's Hospital, Fitzroy, Melbourne, Victoria 3065, Australia.

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http://mcr.aacrjournals.org/cgi/doi/10.1158/1541-7786.MCR-08
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http://dx.doi.org/10.1158/1541-7786.MCR-08-0036DOI Listing
August 2008

c-Jun knockdown sensitizes osteosarcoma to doxorubicin.

Mol Cancer Ther 2008 Jul;7(7):1909-12

Department of Orthopaedics, St. Vincent's Hospital Melbourne, P.O. Box 2900, Fitzroy, Victoria 3065, Australia.

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http://mct.aacrjournals.org/cgi/doi/10.1158/1535-7163.MCT-08
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http://dx.doi.org/10.1158/1535-7163.MCT-08-0086DOI Listing
July 2008

Involvement of c-jun in human liposarcoma growth: supporting data from clinical immunohistochemistry and DNAzyme efficacy.

Cancer Biol Ther 2008 Aug 13;7(8):1297-301. Epub 2008 Aug 13.

Department of Orthopaedics and University of Melbourne Department of Surgery, St. Vincent's Hospital, Fitzroy, Victoria, Australia.

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http://dx.doi.org/10.4161/cbt.7.8.6301DOI Listing
August 2008

Biocompatible chitosan-DNAzyme nanoparticle exhibits enhanced biological activity.

J Microencapsul 2008 Sep;25(6):421-5

Department of Orthopaedics, St. Vincent's Hospital, VIC, Australia.

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http://dx.doi.org/10.1080/02652040802033673DOI Listing
September 2008

Perceptions in health and medical research careers: the Australian Society for Medical Research Workforce Survey.

Med J Aust 2008 May;188(9):520-4

Pharmacoproteomics program, Children's Cancer Institute Australia for Medical Research, Sydney, NSW, Australia.

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May 2008

Downregulation of c-jun results in apoptosis-mediated anti-osteosarcoma activity in an orthotopic model.

Cancer Biol Ther 2008 Jul 4;7(7):1033-6. Epub 2008 Apr 4.

Department of Orthopaedics and University of Melbourne Department of Surgery, St. Vincent's Hospital, Victoria, Australia.

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http://dx.doi.org/10.4161/cbt.7.7.6037DOI Listing
July 2008

DNAzyme technology and cancer therapy: cleave and let die.

Mol Cancer Ther 2008 Feb;7(2):243-51

Department of Orthopaedics, St. Vincent's Hospital Melbourne, Fitzroy, Vic 3065, Australia.

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http://dx.doi.org/10.1158/1535-7163.MCT-07-0510DOI Listing
February 2008

Angiotensin II induction of PDGF-C expression is mediated by AT1 receptor-dependent Egr-1 transactivation.

Nucleic Acids Res 2008 Apr 13;36(6):1941-51. Epub 2008 Feb 13.

The Centre for Vascular Research, The University of New South Wales and Department of Haematology, The Prince of Wales Hospital, Sydney, Australia.

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http://dx.doi.org/10.1093/nar/gkm923DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2330232PMC
April 2008

Angiotensin II-inducible platelet-derived growth factor-D transcription requires specific Ser/Thr residues in the second zinc finger region of Sp1.

Circ Res 2008 Feb 7;102(4):e38-51. Epub 2008 Feb 7.

Centre for Vascular Research, School of Medical Sciences, University of New South Wales, Sydney, Australia.

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http://dx.doi.org/10.1161/CIRCRESAHA.107.167395DOI Listing
February 2008

TRAIL stimulates proliferation of vascular smooth muscle cells via activation of NF-kappaB and induction of insulin-like growth factor-1 receptor.

J Biol Chem 2008 Mar 3;283(12):7754-62. Epub 2008 Jan 3.

Division of Cardiovascular Medicine, University of Cambridge, Box 110, Addenbrooke's Hospital, Cambridge CB2 2QQ, United Kingdom.

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http://dx.doi.org/10.1074/jbc.M706927200DOI Listing
March 2008

Oxidative stress regulates IGF1R expression in vascular smooth-muscle cells via p53 and HDAC recruitment.

Biochem J 2007 Oct;407(1):79-87

Division of Cardiovascular Medicine, University of Cambridge, Box 110, Addenbrooke's Hospital, Cambridge CB2 2QQ, UK.

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http://dx.doi.org/10.1042/BJ20070380DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2267398PMC
October 2007

Yin Yang-1 inhibits vascular smooth muscle cell growth and intimal thickening by repressing p21WAF1/Cip1 transcription and p21WAF1/Cip1-Cdk4-cyclin D1 assembly.

Circ Res 2007 Jul 7;101(2):146-55. Epub 2007 Jun 7.

Centre for Vascular Research, Department of Pathology, University of New South Wales, and Department of Haematology, The Prince of Wales Hospital, Sydney, NSW, Australia.

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http://dx.doi.org/10.1161/CIRCRESAHA.106.145235DOI Listing
July 2007

Collagen antibody-induced arthritis.

Nat Protoc 2006 ;1(5):2512-6

Centre for Vascular Research, Department of Pathology, School of Medical Sciences, The University of New South Wales, Sydney, NSW 2052, Australia.

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http://dx.doi.org/10.1038/nprot.2006.393DOI Listing
October 2007

Suppression of growth factor expression and human vascular smooth muscle cell growth by small interfering RNA targeting EGR-1.

J Cell Biochem 2007 Apr;100(6):1526-35

Department of Pathology, Centre for Vascular Research, The University of New South Wales, Sydney, Australia.

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http://dx.doi.org/10.1002/jcb.21145DOI Listing
April 2007

Rat models of myocardial infarction. Pathogenetic insights and clinical relevance.

Thromb Haemost 2006 Nov;96(5):602-10

Vascular Biology Laboratory, Anzac Research Institute, University of Sydney and Cardiology Department, Concord Repatriation General Hospital, New South Wales, Australia.

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November 2006

Health and medical research funding: an investment in Australia's future.

Med J Aust 2006 Oct;185(7):348-9

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October 2006

JUN siRNA regulates matrix metalloproteinase-2 expression, microvascular endothelial growth and retinal neovascularisation.

J Cell Sci 2006 Aug 17;119(Pt 15):3219-26. Epub 2006 Jul 17.

Centre for Vascular Research, The University of New South Wales and Department of Haematology, The Prince of Wales Hospital.

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http://jcs.biologists.org/cgi/doi/10.1242/jcs.03059
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August 2006

Suppression of vascular permeability and inflammation by targeting of the transcription factor c-Jun.

Nat Biotechnol 2006 Jul 2;24(7):856-63. Epub 2006 Jul 2.

Centre for Vascular Research, University of New South Wales, and Department of Haematology, The Prince of Wales Hospital, Sydney NSW 2031, Australia.

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http://dx.doi.org/10.1038/nbt1225DOI Listing
July 2006

Early growth response-1 in cardiovascular pathobiology.

Circ Res 2006 Feb;98(2):186-91

Centre for Vascular Research, Department of Pathology, The University of New South Wales, The Prince of Wales Hospital, Sydney, Australia.

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http://dx.doi.org/10.1161/01.RES.0000200177.53882.c3DOI Listing
February 2006

Peroxide-inducible Ets-1 mediates platelet-derived growth factor receptor-alpha gene transcription in vascular smooth muscle cells.

Am J Pathol 2005 Oct;167(4):1149-59

Centre for Vascular Research, Department of Pathology, The University of New South Wales, Sydney, NSW 2052, Australia.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1603673PMC
http://dx.doi.org/10.1016/s0002-9440(10)61203-5DOI Listing
October 2005

Inducible platelet-derived growth factor D-chain expression by angiotensin II and hydrogen peroxide involves transcriptional regulation by Ets-1 and Sp1.

Blood 2006 Mar 27;107(6):2322-9. Epub 2005 Sep 27.

Centre for Vascular Research, Department of Pathology, University of New South Wales, Sydney NSW 2052 Australia.

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http://dx.doi.org/10.1182/blood-2005-06-2377DOI Listing
March 2006

Early growth response gene 1 (EGR1) regulates heparanase gene transcription in tumor cells.

J Biol Chem 2005 Oct 10;280(42):35136-47. Epub 2005 Aug 10.

Cancer and Vascular Biology Group, Division of Immunology and Genetics, The John Curtin School of Medical Research, The Australian National University, Acton ACT 2601.

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http://dx.doi.org/10.1074/jbc.M503414200DOI Listing
October 2005

Suppressing a sick heart.

Nat Med 2005 Aug;11(8):828-9

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http://www.nature.com/articles/nm0805-828
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August 2005

Fibroblast growth factor 2 and the transcription factor Egr-1 localise to endothelial cell microvascular channels in human coronary artery occlusion.

Thromb Haemost 2005 Jan;93(1):172-4

Centre for Vascular Research, School of Medical Sciences, University of New South Wales, Sydney, Australia.

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January 2005