Leszek Lisowski

Leszek Lisowski

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Leszek Lisowski

Leszek Lisowski

Publications by authors named "Leszek Lisowski"

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31Publications

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Age-Related Seroprevalence of Antibodies Against AAV-LK03 in a UK Population Cohort.

Hum Gene Ther 2019 Jan 19;30(1):79-87. Epub 2018 Oct 19.

1 Genetics and Genomic Medicine Programme, Great Ormond Street Institute of Child Health, University College London, London, United Kingdom.

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http://www.liebertpub.com/doi/10.1089/hum.2018.098
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http://dx.doi.org/10.1089/hum.2018.098DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343184PMC
January 2019

Directed Evolution of Adeno-Associated Virus Vectors in Human Cardiomyocytes for Cardiac Gene Therapy.

Heart Lung Circ 2018 Nov;27(11):1270-1273

Center for Heart Research, The Westmead Institute for Medical Research, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW, Australia; Department of Cardiology, Westmead Hospital, Sydney, NSW, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.hlc.2018.08.014DOI Listing
November 2018

An Atypical Parvovirus Drives Chronic Tubulointerstitial Nephropathy and Kidney Fibrosis.

Cell 2018 10 13;175(2):530-543.e24. Epub 2018 Sep 13.

Centenary Institute, Faculty of Medicine and Health, The University of Sydney, Camperdown, NSW 2050, Australia; Discipline of Dermatology, Faculty of Medicine and Health, University of Sydney, NSW 2006, Australia; Department of Dermatology, Royal Prince Alfred Hospital, Camperdown, NSW 2050, Australia; Department of Dermatology, Medical University of Vienna, Vienna 1090, Austria. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00928674183102
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http://dx.doi.org/10.1016/j.cell.2018.08.013DOI Listing
October 2018

Identification of liver-specific enhancer-promoter activity in the 3' untranslated region of the wild-type AAV2 genome.

Nat Genet 2017 Aug 19;49(8):1267-1273. Epub 2017 Jun 19.

Gene Therapy Research Unit, Children's Medical Research Institute and Sydney Children's Hospitals Network, University of Sydney, Sydney, New South Wales, Australia.

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http://dx.doi.org/10.1038/ng.3893DOI Listing
August 2017

Adeno-associated virus serotypes for gene therapeutics.

Curr Opin Pharmacol 2015 Oct 25;24:59-67. Epub 2015 Aug 25.

Gene Therapy Research Unit, The Children's Hospital at Westmead and Children's Medical Research Institute, Locked Bag 4001, Westmead 2145, NSW, Australia; Discipline of Paediatrics and Child Health, The University of Sydney, NSW, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.coph.2015.07.006DOI Listing
October 2015

Second generation codon optimized minicircle (CoMiC) for nonviral reprogramming of human adult fibroblasts.

Methods Mol Biol 2014 ;1181:1-13

Lorry I. Lokey Stem Cell Research Building, Stanford University School of Medicine, 265 Campus Drive, Room G1105, Stanford, CA, 94305-5454, USA.

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http://link.springer.com/10.1007/978-1-4939-1047-2_1
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http://dx.doi.org/10.1007/978-1-4939-1047-2_1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385867PMC
March 2015

Genome editing of isogenic human induced pluripotent stem cells recapitulates long QT phenotype for drug testing.

J Am Coll Cardiol 2014 Aug;64(5):451-9

Department of Medicine, Division of Cardiology, Stanford University School of Medicine, Stanford, California; Stanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, California; Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, California. Electronic address:

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http://dx.doi.org/10.1016/j.jacc.2014.04.057DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4149735PMC
August 2014

Somatic correction of junctional epidermolysis bullosa by a highly recombinogenic AAV variant.

Mol Ther 2014 Apr 6;22(4):725-33. Epub 2014 Jan 6.

Program in Epithelial Biology, Stanford University, School of Medicine, Stanford, California, USA.

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http://dx.doi.org/10.1038/mt.2013.290DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3982486PMC
April 2014

Selection and evaluation of clinically relevant AAV variants in a xenograft liver model.

Nature 2014 Feb 25;506(7488):382-6. Epub 2013 Dec 25.

Stanford University, School of Medicine, Departments of Pediatrics and Genetics, 269 Campus Drive, Stanford, California 94305, USA.

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http://dx.doi.org/10.1038/nature12875DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3939040PMC
February 2014

Comparison of transduction efficiency among various lentiviruses containing GFP reporter in bone marrow hematopoietic stem cell transplantation.

Exp Hematol 2013 Nov 14;41(11):934-43. Epub 2013 Aug 14.

Department of Pediatrics, Program in Immunology, Program in Human Gene Therapy, Stanford University School of Medicine, Stanford, CA, USA.

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http://dx.doi.org/10.1016/j.exphem.2013.07.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3833897PMC
November 2013

The anti-genomic (negative) strand of Hepatitis C Virus is not targetable by shRNA.

Nucleic Acids Res 2013 Apr 8;41(6):3688-98. Epub 2013 Feb 8.

Department of Pediatrics, School of Medicine, Stanford University, 269 Pasteur Drive, Stanford, CA 94305, USA.

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http://dx.doi.org/10.1093/nar/gkt068DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3616702PMC
April 2013

rAAV-mediated tumorigenesis: still unresolved after an AAV assault.

Mol Ther 2012 Nov;20(11):2014-7

Departments of Pediatrics and Genetics, Stanford University, Stanford, California 94305, USA.

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http://dx.doi.org/10.1038/mt.2012.220DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3498811PMC
November 2012

Ribosomal DNA integrating rAAV-rDNA vectors allow for stable transgene expression.

Mol Ther 2012 Oct 18;20(10):1912-23. Epub 2012 Sep 18.

Stanford University, Departments of Pediatrics and Genetics, Stanford, California 94305-5164, USA.

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http://dx.doi.org/10.1038/mt.2012.164DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3464642PMC
October 2012

AAV vectors containing rDNA homology display increased chromosomal integration and transgene persistence.

Mol Ther 2012 Oct 18;20(10):1902-11. Epub 2012 Sep 18.

Oregon Stem Cell Center, Papé Family Pediatric Research Institute, Oregon Health and Science University, Portland, Oregon 97239-3098, USA.

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http://dx.doi.org/10.1038/mt.2012.157DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3464636PMC
October 2012

Supplying clotting factors from hematopoietic stem cell-derived erythroid and megakaryocytic lineage cells.

Mol Ther 2009 Dec 20;17(12):1994-9. Epub 2009 Oct 20.

Center for Cell Engineering, Molecular Pharmacology and Chemistry Program, Memorial Sloan-Kettering Cancer Center, New York, New York 10065, USA.

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http://dx.doi.org/10.1038/mt.2009.238DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2814379PMC
December 2009

Transient in vivo beta-globin production after lentiviral gene transfer to hematopoietic stem cells in the nonhuman primate.

Hum Gene Ther 2009 Jun;20(6):563-72

Molecular and Clinical Hematology Branch (MCHB), National Institutes of Diabetes and Digestive and Kidney Disorders (NIDDK) , National Institutes of Health (NIH), Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1089/hum.2008.186DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2828625PMC
June 2009

Current status of globin gene therapy for the treatment of beta-thalassaemia.

Br J Haematol 2008 May;141(3):335-45

Memorial Sloan-Kettering Cancer Center, and Weill Graduate School of Mediccal Sciences, Cornell University, New York, NY 10021, USA.

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http://dx.doi.org/10.1111/j.1365-2141.2008.07098.xDOI Listing
May 2008

Locus control region elements HS1 and HS4 enhance the therapeutic efficacy of globin gene transfer in beta-thalassemic mice.

Blood 2007 Dec 5;110(13):4175-8. Epub 2007 Oct 5.

Center for Cell Engineering, Gene Transfer and Somatic Cell Engineering Laboratory, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA.

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http://dx.doi.org/10.1182/blood-2007-08-108647DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2234778PMC
December 2007

Progress toward the genetic treatment of the beta-thalassemias.

Ann N Y Acad Sci 2005 ;1054:78-91

Gene Transfer and Gene Expression Laboratory, Memorial Sloan-Kettering Cancer Center, Box 182, 1275 York Ave., New York, NY 10021, USA.

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http://dx.doi.org/10.1196/annals.1345.010DOI Listing
July 2006

A genetic strategy to treat sickle cell anemia by coregulating globin transgene expression and RNA interference.

Nat Biotechnol 2006 Jan 25;24(1):89-94. Epub 2005 Dec 25.

Laboratory of Gene Transfer and Gene Expression, Sloan-Kettering Institute, New York, New York 10021, USA.

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http://dx.doi.org/10.1038/nbt1176DOI Listing
January 2006

Globin gene transfer for treatment of the beta-thalassemias and sickle cell disease.

Best Pract Res Clin Haematol 2004 Sep;17(3):517-34

Laboratory of Gene Transfer and Gene Expression, Gene Transfer and Somatic Cell Engineering Facility, Box 182 Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA.

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http://dx.doi.org/10.1016/j.beha.2004.08.002DOI Listing
September 2004