Publications by authors named "Leslie Bell"

19Publications

Comparison of treatment planning approaches for spatially fractionated irradiation of deep tumors.

Authors:
Khadija Sheikh William T Hrinivich Leslie A Bell Joseph A Moore Wolfram Laub Akila N Viswanathan Yulong Yan Todd R McNutt Jeffrey Meyer

J Appl Clin Med Phys 2019 Jun 21;20(6):125-133. Epub 2019 May 21.

Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

View Article and Find Full Text PDF
June 2019

Providing Restricted Access to an Electronic Medical Record for Research Monitoring.

Authors:
Leslie Bell Stephanie Gentilin Susan Sonne Toni Mauney Patrick Flume

Clin Res (Alex) 2018 13;32(3). Epub 2018 Mar 13.

Medical University of South Carolina.

View Article and Find Full Text PDF
March 2018

Response to Commentary: Regulatory Support Improves Subsequent IRB Approval Rates in Studies Initially Deemed Not Ready for Review-A CTSA Institution's Experience.

Authors:
Susan Sonne Stephanie Gentilin Royce R Sampson Leslie Bell Toni Mauney Summer Young Katherine Bright Patrick Flume

J Empir Res Hum Res Ethics 2018 04 18;13(2):148. Epub 2018 Jan 18.

View Article and Find Full Text PDF
April 2018

Regulatory Support Improves Subsequent IRB Approval Rates in Studies Initially Deemed Not Ready for Review: A CTSA Institution's Experience.

Authors:
Susan Sonne Stephanie Gentilin Royce R Sampson Leslie Bell Toni Mauney Summer Young Katherine Bright Patrick Flume

J Empir Res Hum Res Ethics 2018 04 18;13(2):139-144. Epub 2018 Jan 18.

1 Medical University of South Carolina, Charleston, SC, USA.

View Article and Find Full Text PDF
April 2018

Promoting Radiation Safety Protocols in Computed Tomography.

Authors:
Leslie Ann Bell

Radiol Technol 2016 Jan-Feb;87(3):344-8

View Article and Find Full Text PDF
October 2016

The Unseen and the Unheard: South African and Indian Responses to Social Invisibility and Psychic Pain.

Authors:
Leslie Bell

J Am Psychoanal Assoc 2015 Oct;63(5):965-76

View Article and Find Full Text PDF
October 2015

C. elegans NIMA-related kinases NEKL-2 and NEKL-3 are required for the completion of molting.

Authors:
John Yochem Vladimir Lažetić Leslie Bell Lihsia Chen David Fay

Dev Biol 2015 Feb 16;398(2):255-66. Epub 2014 Dec 16.

Department of Molecular Biology, College of Agriculture and Natural Resources, University of Wyoming, Laramie, WY 82071, United States. Electronic address:

View Article and Find Full Text PDF
February 2015

A novel nondevelopmental role of the sax-7/L1CAM cell adhesion molecule in synaptic regulation in Caenorhabditis elegans.

Authors:
Karla Opperman Melinda Moseley-Alldredge John Yochem Leslie Bell Tony Kanayinkal Lihsia Chen

Genetics 2015 Feb 8;199(2):497-509. Epub 2014 Dec 8.

Department of Genetics, Cell Biology, and Development, University of Minnesota, Minneapolis, Minnesota 55455 Developmental Biology Center, University of Minnesota, Minneapolis, Minnesota 55455

View Article and Find Full Text PDF
February 2015

A numerical method for analysis of in vitro time-dependent inhibition data. Part 2. Application to experimental data.

Authors:
Ken Korzekwa Donald Tweedie Upendra A Argikar Andrea Whitcher-Johnstone Leslie Bell Shari Bickford Swati Nagar

Drug Metab Dispos 2014 Sep 17;42(9):1587-95. Epub 2014 Jun 17.

Department of Pharmaceutical Sciences, Temple University School of Pharmacy, Philadelphia, Pennsylvania (K.K., S.N.); Drug Metabolism and Pharmacokinetics, Boehringer Ingelheim, Ridgefield, Connecticut (D.T., A.W.-J.); and Analytical Sciences and Imaging (U.A.A.) and Metabolism and Pharmacokinetics (L.B., S.B.), Novartis Institutes for BioMedical Research Inc., Cambridge, Massachusetts

View Article and Find Full Text PDF
September 2014

Metabolically Stable tert-Butyl Replacement.

Authors:
David Barnes-Seeman Monish Jain Leslie Bell Suzie Ferreira Scott Cohen Xiao-Hui Chen Jakal Amin Brad Snodgrass Panos Hatsis

ACS Med Chem Lett 2013 Jun 22;4(6):514-6. Epub 2013 Apr 22.

Department of Metabolism and Pharmacokinetics, Novartis Institutes for Biomedical Research , 250 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States.

View Article and Find Full Text PDF
June 2013

Caenorhabditis elegans reveals a FxNPxY-independent low-density lipoprotein receptor internalization mechanism mediated by epsin1.

Authors:
Yuan-Lin Kang John Yochem Leslie Bell Erika B Sorensen Lihsia Chen Sean D Conner

Mol Biol Cell 2013 Feb 14;24(3):308-18. Epub 2012 Dec 14.

Department of Genetics, Cell Biology, and Development and the Developmental Biology Center, University of Minnesota, Minneapolis, MN 55455, USA.

View Article and Find Full Text PDF
February 2013

Probe ADME and test hypotheses: a PATH beyond clearance in vitro-in vivo correlations in early drug discovery.

Authors:
Leslie C Bell Jianling Wang

Expert Opin Drug Metab Toxicol 2012 Sep 11;8(9):1131-55. Epub 2012 Jun 11.

Novartis Institutes for Biomedical Research, Metabolism and Pharmacokinetics, Cambridge, MA 02139, USA.

View Article and Find Full Text PDF
September 2012

A new structural alert for benzimidazoles: 2,6-dimethylphenyl substituents increase mutagenic potential and time-dependent CYP3A4 inhibition risk.

Authors:
Youngshin Kwak Gary Coppola Cornelia J Forster Thomas A Gilmore Yongjin Gong Aaron Kanter Alan Neubert Bryan Stroup Paul Szklennik Susanne Glowienke Pascal Stadelmann Leslie Bell Shari Bickford Eric Gangl Mithat Gunduz Monish Jain Jenny Zhan Michael H Serrano-Wu

Bioorg Med Chem Lett 2011 Mar 11;21(5):1422-4. Epub 2011 Jan 11.

Global Discovery Chemistry, Cambridge, MA 02139, USA.

View Article and Find Full Text PDF
March 2011

High-throughput analysis of in vitro cytochrome p450 inhibition samples using mass spectrometry coupled with an integrated liquid chromatography/autosampler system.

Authors:
Ann Brown Shari Bickford Panos Hatsis Jakal Amin Leslie Bell Shawn Harriman

Rapid Commun Mass Spectrom 2010 Apr;24(8):1207-10

View Article and Find Full Text PDF
April 2010

Evaluation of fluorescence- and mass spectrometry-based CYP inhibition assays for use in drug discovery.

Authors:
Leslie Bell Shari Bickford Phong Hung Nguyen Jianling Wang Timothy He Bailin Zhang Yannick Friche Alfred Zimmerlin Laszlo Urban Dejan Bojanic

J Biomol Screen 2008 Jun 12;13(5):343-53. Epub 2008 May 12.

ADME Profiling Cambridge, Metabolism and Pharmacokinetics, Global Discovery Chemistry, Novartis Institutes for Biomedical Research, Cambridge, Massachusetts 02139, USA.

View Article and Find Full Text PDF
June 2008

High-throughput in vitro profiling assays: lessons learnt from experiences at Novartis.

Authors:
Bernard Faller Jianling Wang Alfred Zimmerlin Leslie Bell Jacques Hamon Steven Whitebread Kamal Azzaoui Dejan Bojanic Laszlo Urban

Expert Opin Drug Metab Toxicol 2006 Dec;2(6):823-33

Novartis Institutes for BioMedical Research, Basel, Switzerland.

View Article and Find Full Text PDF
December 2006

The molecular identities of the Caenorhabditis elegans intraflagellar transport genes dyf-6, daf-10 and osm-1.

Authors:
Leslie R Bell Steven Stone John Yochem Jocelyn E Shaw Robert K Herman

Genetics 2006 Jul 30;173(3):1275-86. Epub 2006 Apr 30.

Department of Genetics, Cell Biology, and Development, University of Minnesota, Minneapolis, Minnesota 55455, USA.

View Article and Find Full Text PDF
July 2006

Isopentenyl-diphosphate isomerase is essential for viability of Caenorhabditis elegans.

Authors:
John Yochem David H Hall Leslie R Bell Edward M Hedgecock Robert K Herman

Mol Genet Genomics 2005 Apr 12;273(2):158-66. Epub 2005 Mar 12.

Department of Genetics, Cell Biology and Development, University of Minnesota, 6-160 Jackson Hall, 321 Church Street SE, Minneapolis, MN 55455, USA.

View Article and Find Full Text PDF
April 2005

The identities of sym-2, sym-3 and sym-4, three genes that are synthetically lethal with mec-8 in Caenorhabditis elegans.

Authors:
John Yochem Leslie R Bell Robert K Herman

Genetics 2004 Nov;168(3):1293-306

Department of Genetics, Cell Biology, and Development, University of Minnesota, Minneapolis, Minnesota 55455, USA.

View Article and Find Full Text PDF
November 2004