Publications by authors named "Leslie Bell"

19Publications

Comparison of treatment planning approaches for spatially fractionated irradiation of deep tumors.

J Appl Clin Med Phys 2019 Jun 21;20(6):125-133. Epub 2019 May 21.

Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

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June 2019

C. elegans NIMA-related kinases NEKL-2 and NEKL-3 are required for the completion of molting.

Dev Biol 2015 Feb 16;398(2):255-66. Epub 2014 Dec 16.

Department of Molecular Biology, College of Agriculture and Natural Resources, University of Wyoming, Laramie, WY 82071, United States. Electronic address:

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February 2015

A novel nondevelopmental role of the sax-7/L1CAM cell adhesion molecule in synaptic regulation in Caenorhabditis elegans.

Genetics 2015 Feb 8;199(2):497-509. Epub 2014 Dec 8.

Department of Genetics, Cell Biology, and Development, University of Minnesota, Minneapolis, Minnesota 55455 Developmental Biology Center, University of Minnesota, Minneapolis, Minnesota 55455

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February 2015

A numerical method for analysis of in vitro time-dependent inhibition data. Part 2. Application to experimental data.

Drug Metab Dispos 2014 Sep 17;42(9):1587-95. Epub 2014 Jun 17.

Department of Pharmaceutical Sciences, Temple University School of Pharmacy, Philadelphia, Pennsylvania (K.K., S.N.); Drug Metabolism and Pharmacokinetics, Boehringer Ingelheim, Ridgefield, Connecticut (D.T., A.W.-J.); and Analytical Sciences and Imaging (U.A.A.) and Metabolism and Pharmacokinetics (L.B., S.B.), Novartis Institutes for BioMedical Research Inc., Cambridge, Massachusetts

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September 2014

Metabolically Stable tert-Butyl Replacement.

ACS Med Chem Lett 2013 Jun 22;4(6):514-6. Epub 2013 Apr 22.

Department of Metabolism and Pharmacokinetics, Novartis Institutes for Biomedical Research , 250 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States.

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June 2013

Caenorhabditis elegans reveals a FxNPxY-independent low-density lipoprotein receptor internalization mechanism mediated by epsin1.

Mol Biol Cell 2013 Feb 14;24(3):308-18. Epub 2012 Dec 14.

Department of Genetics, Cell Biology, and Development and the Developmental Biology Center, University of Minnesota, Minneapolis, MN 55455, USA.

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February 2013

Probe ADME and test hypotheses: a PATH beyond clearance in vitro-in vivo correlations in early drug discovery.

Expert Opin Drug Metab Toxicol 2012 Sep 11;8(9):1131-55. Epub 2012 Jun 11.

Novartis Institutes for Biomedical Research, Metabolism and Pharmacokinetics, Cambridge, MA 02139, USA.

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September 2012

Evaluation of fluorescence- and mass spectrometry-based CYP inhibition assays for use in drug discovery.

J Biomol Screen 2008 Jun 12;13(5):343-53. Epub 2008 May 12.

ADME Profiling Cambridge, Metabolism and Pharmacokinetics, Global Discovery Chemistry, Novartis Institutes for Biomedical Research, Cambridge, Massachusetts 02139, USA.

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June 2008

The molecular identities of the Caenorhabditis elegans intraflagellar transport genes dyf-6, daf-10 and osm-1.

Genetics 2006 Jul 30;173(3):1275-86. Epub 2006 Apr 30.

Department of Genetics, Cell Biology, and Development, University of Minnesota, Minneapolis, Minnesota 55455, USA.

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July 2006

Isopentenyl-diphosphate isomerase is essential for viability of Caenorhabditis elegans.

Mol Genet Genomics 2005 Apr 12;273(2):158-66. Epub 2005 Mar 12.

Department of Genetics, Cell Biology and Development, University of Minnesota, 6-160 Jackson Hall, 321 Church Street SE, Minneapolis, MN 55455, USA.

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April 2005

The identities of sym-2, sym-3 and sym-4, three genes that are synthetically lethal with mec-8 in Caenorhabditis elegans.

Genetics 2004 Nov;168(3):1293-306

Department of Genetics, Cell Biology, and Development, University of Minnesota, Minneapolis, Minnesota 55455, USA.

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November 2004