Lesley Smyth

Lesley Smyth

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Lesley Smyth

Lesley Smyth

Publications by authors named "Lesley Smyth"

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Application of carbon nanotubes in cancer vaccines: Achievements, challenges and chances.

J Control Release 2019 Mar 16;297:79-90. Epub 2019 Jan 16.

Institute of Pharmaceutical Science, School of Cancer and Pharmaceutical Science, Faculty of Life Sciences & Medicine, King's College London, Franklin-Wilkins Building, London SE1 9NH, United Kingdom. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01683659193003
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http://dx.doi.org/10.1016/j.jconrel.2019.01.017DOI Listing
March 2019

Membrane Radiolabelling of Exosomes for Comparative Biodistribution Analysis in Immunocompetent and Immunodeficient Mice - A Novel and Universal Approach.

Theranostics 2019 28;9(6):1666-1682. Epub 2019 Feb 28.

Institute of Pharmaceutical Science, Faculty of Life Sciences & Medicine, King's College London, Franklin-Wilkins Building, 150 Stamford Street, London SE1 9NH, United Kingdom.

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http://www.thno.org/v09p1666.htm
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http://dx.doi.org/10.7150/thno.27891DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6485196PMC
February 2019

Nox2 in regulatory T cells promotes angiotensin II-induced cardiovascular remodeling.

J Clin Invest 2018 07 11;128(7):3088-3101. Epub 2018 Jun 11.

King's College London British Heart Foundation Centre, School of Cardiovascular Medicine and Sciences, London, United Kingdom.

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http://dx.doi.org/10.1172/JCI97490DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6025997PMC
July 2018

Treg therapy in transplantation: a general overview.

Transpl Int 2017 Aug 6;30(8):745-753. Epub 2017 Feb 6.

Immunoregulation Laboratory, Division of Transplantation Immunology & Mucosal Biology, MRC Centre for Transplantation, King's College London, Guy's Hospital, London, UK.

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http://dx.doi.org/10.1111/tri.12909DOI Listing
August 2017

Dual stimulation of antigen presenting cells using carbon nanotube-based vaccine delivery system for cancer immunotherapy.

Biomaterials 2016 10 14;104:310-22. Epub 2016 Jul 14.

Institute of Pharmaceutical Science, Faculty of Life Sciences & Medicine, King's College London, Franklin-Wilkins Building, London SE1 9NH, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.biomaterials.2016.07.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4993816PMC
October 2016

What Is Direct Allorecognition?

Curr Transplant Rep 2016 7;3(4):275-283. Epub 2016 Oct 7.

MRC Centre for Transplantation, King's College London, Guy's Hospital, London, SE1 9RT UK ; NIHR Biomedical Research Centre, Guy's & St Thomas' NHS Foundation Trust & King's College London, Guy's Hospital, London, SE1 9RT UK.

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http://dx.doi.org/10.1007/s40472-016-0115-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5107184PMC
October 2016

Antigen-specificity using chimeric antigen receptors: the future of regulatory T-cell therapy?

Biochem Soc Trans 2016 Apr;44(2):342-8

Immunoregulation Laboratory, MRC Centre for Transplantation, Guy's Hospital, King's College London, London SE1 9RT, U.K. NIHR Biomedical Research Centre, Guy's & St Thomas' NHS Foundation Trust & King's College London, London SE1 9RT, U.K.

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http://dx.doi.org/10.1042/BST20150247DOI Listing
April 2016

Carbon nanotubes' surface chemistry determines their potency as vaccine nanocarriers in vitro and in vivo.

J Control Release 2016 Mar 21;225:205-16. Epub 2016 Jan 21.

Institute of Pharmaceutical Science, Faculty of Life Sciences & Medicine, King's College London, Franklin-Wilkins Building, London SE1 9NH, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.jconrel.2016.01.030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778609PMC
March 2016

MicroRNAs affect dendritic cell function and phenotype.

Immunology 2015 Feb;144(2):197-205

MRC Centre for Transplantation, King's College London, Guy's Hospital, London, UK.

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http://dx.doi.org/10.1111/imm.12390DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4298414PMC
February 2015

Regulatory T cell-derived exosomes: possible therapeutic and diagnostic tools in transplantation.

Front Immunol 2014 5;5:555. Epub 2014 Nov 5.

Medical Research Council (MRC) Centre for Transplantation, King's College London, Guy's Hospital , London , UK.

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http://dx.doi.org/10.3389/fimmu.2014.00555DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4220709PMC
November 2014

Monitoring the efficacy of dendritic cell vaccination by early detection of (99m) Tc-HMPAO-labelled CD4(+) T cells.

Eur J Immunol 2014 Jul 14;44(7):2188-91. Epub 2014 Apr 14.

Medical Research Council (MRC) Centre for Transplantation, King's College London, King's Health Partners, Guy's Hospital, London, United Kingdom; Division of Imaging Sciences and Biomedical Engineering, King's College London, St. Thomas Hospital, London, United Kingdom.

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http://dx.doi.org/10.1002/eji.201344337DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4211358PMC
July 2014

CD73 expression on extracellular vesicles derived from CD4+ CD25+ Foxp3+ T cells contributes to their regulatory function.

Eur J Immunol 2013 Sep 15;43(9):2430-40. Epub 2013 Jul 15.

MRC Centre for Transplantation, King's College London, Guy's Hospital, London, UK.

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http://dx.doi.org/10.1002/eji.201242909DOI Listing
September 2013

C3a and C5a promote renal ischemia-reperfusion injury.

J Am Soc Nephrol 2012 Sep 12;23(9):1474-85. Epub 2012 Jul 12.

MRC Centre for Transplantation, King's College London, London SE1 9RT, United Kingdom.

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http://dx.doi.org/10.1681/ASN.2011111072DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431410PMC
September 2012

Acquisition of MHC:peptide complexes by dendritic cells contributes to the generation of antiviral CD8+ T cell immunity in vivo.

J Immunol 2012 Sep 20;189(5):2274-82. Epub 2012 Jul 20.

Medical Research Council Centre for Transplantation, King's College London, London SE1 9RT, United Kingdom.

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http://dx.doi.org/10.4049/jimmunol.1200664DOI Listing
September 2012

In vivo SPECT reporter gene imaging of regulatory T cells.

PLoS One 2011 17;6(10):e25857. Epub 2011 Oct 17.

Medical Research Council, Centre for Transplantation, King's College London, King's Health Partners, Guy's Hospital, London, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0025857PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3197183PMC
April 2012

Cell therapy to promote transplantation tolerance: a winning strategy?

Immunotherapy 2011 Apr;3(4 Suppl):28-31

Medical Research Council Centre for Transplantation and National Institute for Health Research Comprehensive Biomedical Research Centre at Guy's and St Thomas', NHS Foundation Trust, King's College London, UK.

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http://dx.doi.org/10.2217/imt.11.42DOI Listing
April 2011

The relative efficiency of acquisition of MHC:peptide complexes and cross-presentation depends on dendritic cell type.

J Immunol 2008 Sep;181(5):3212-20

Department of Nephrology and Transplantation, King's College London, School of Medicine, Guy's Hospital, London, United Kingdom.

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http://dx.doi.org/10.4049/jimmunol.181.5.3212DOI Listing
September 2008

A novel pathway of antigen presentation by dendritic and endothelial cells: Implications for allorecognition and infectious diseases.

Transplantation 2006 Jul;82(1 Suppl):S15-8

Department of Nephrology and Transplantation, Kings College London, Guy's Hospital, London, United Kingdom.

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https://insights.ovid.com/crossref?an=00007890-200607151-000
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http://dx.doi.org/10.1097/01.tp.0000231347.06149.caDOI Listing
July 2006

cMet and Fas receptor interaction inhibits death-inducing signaling complex formation in endothelial cells.

Hypertension 2005 Jul 23;46(1):100-6. Epub 2005 May 23.

Molecular Hematology and Cancer Biology Unit, Institute of Child Health, University College London, 30 Guilford St, London WC1N 1EH, United Kingdom.

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https://www.ahajournals.org/doi/10.1161/01.HYP.0000167991.82
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http://dx.doi.org/10.1161/01.HYP.0000167991.82153.16DOI Listing
July 2005