Publications by authors named "Lesley Mathews Griner"

24Publications

Generation of High-Throughput Three-Dimensional Tumor Spheroids for Drug Screening.

J Vis Exp 2018 09 5(139). Epub 2018 Sep 5.

Oncology Drug Discovery: Molecular Pharmacology, Novartis Institutes for Biomedical Research.

View Article and Find Full Text PDF
September 2018

Large-scale pharmacological profiling of 3D tumor models of cancer cells.

Cell Death Dis 2016 12 1;7(12):e2492. Epub 2016 Dec 1.

National Center for Advancing Translational Sciences, Division of Pre-Clinical Innovation, National Institutes of Health, Bethesda, MD, USA.

View Article and Find Full Text PDF
December 2016

Chemical Screens Identify Drugs that Enhance or Mitigate Cellular Responses to Antibody-Toxin Fusion Proteins.

PLoS One 2016 24;11(8):e0161415. Epub 2016 Aug 24.

Division of Preclinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland, 20850, United States of America.

View Article and Find Full Text PDF
July 2017

Efficacy and Mechanism of Action of Low Dose Emetine against Human Cytomegalovirus.

PLoS Pathog 2016 06 23;12(6):e1005717. Epub 2016 Jun 23.

Department of Pediatrics, Division of Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America.

View Article and Find Full Text PDF
June 2016

Targeting Estrogen Receptor Signaling with Fulvestrant Enhances Immune and Chemotherapy-Mediated Cytotoxicity of Human Lung Cancer.

Clin Cancer Res 2016 Dec 7;22(24):6204-6216. Epub 2016 Jun 7.

Laboratory of Tumor Immunology and Biology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland.

View Article and Find Full Text PDF
December 2016

Ranking Differential Drug Activities from Dose-Response Synthetic Lethality Screens.

J Biomol Screen 2016 Oct 25;21(9):942-55. Epub 2016 Apr 25.

Division of Preclinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD, USA

View Article and Find Full Text PDF
October 2016

Selective targeting of JAK/STAT signaling is potentiated by Bcl-xL blockade in IL-2-dependent adult T-cell leukemia.

Proc Natl Acad Sci U S A 2015 Oct 22;112(40):12480-5. Epub 2015 Sep 22.

Lymphoid Malignancies Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892;

View Article and Find Full Text PDF
October 2015