Leping Li

Leping Li

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Leping Li

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Inhibitory effects of miR‑26b‑5p on thyroid cancer.

Mol Med Rep 2019 Aug 31;20(2):1196-1202. Epub 2019 May 31.

Department of General Surgery, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, Shandong 250101, P.R. China.

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http://dx.doi.org/10.3892/mmr.2019.10315DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6625412PMC
August 2019

GDF15 promotes epithelial-to-mesenchymal transition in colorectal [corrected].

Artif Cells Nanomed Biotechnol 2018 17;46(sup2):652-658. Epub 2018 May 17.

a Department of Gastrointestinal Surgery , Shandong Provincial Hospital Affiliated to Shandong University , Jinan , China.

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http://dx.doi.org/10.1080/21691401.2018.1466146DOI Listing
June 2019

Glypican 6 is a putative biomarker for metastatic progression of cutaneous melanoma.

PLoS One 2019 14;14(6):e0218067. Epub 2019 Jun 14.

Biostatistics and Computational Biology Branch, National Institute of Environmental Health Sciences, Durham, North Carolina, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0218067PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6568403PMC
June 2019

Expression of Interleukin-6 and Integrin ανβ6 in Colon Cancer: Association with Clinical Outcomes and Prognostic Implications.

Cancer Invest 2019 14;37(3):174-184. Epub 2019 Apr 14.

a Department of Gastrointestinal Surgery , Provincial Hospital Affiliated to Shandong University , Jinan , China.

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http://dx.doi.org/10.1080/07357907.2019.1597103DOI Listing
April 2019

Increased musashi 2 expression indicates a poor prognosis and promotes malignant phenotypes in gastric cancer.

Oncol Lett 2019 Mar 4;17(3):2599-2606. Epub 2019 Jan 4.

Department of Gastrointestinal Surgery, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, Shandong 250021, P.R. China.

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http://dx.doi.org/10.3892/ol.2019.9889DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365935PMC
March 2019

The effects of Tim-3 activation on T-cells in gastric cancer progression.

Oncol Lett 2019 Feb 21;17(2):1461-1466. Epub 2018 Nov 21.

Department of Gastrointestinal Surgery, Provincial Hospital Affiliated to Shandong University, Jinan, Shandong 250021, P.R. China.

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http://www.spandidos-publications.com/10.3892/ol.2018.9743
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http://dx.doi.org/10.3892/ol.2018.9743DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341528PMC
February 2019

Expert consensus on multidisciplinary therapy of colorectal cancer with lung metastases (2019 edition).

J Hematol Oncol 2019 02 14;12(1):16. Epub 2019 Feb 14.

Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Peking University Cancer Hospital & Institute, No. 52, Fucheng Road, Haidian District, Beijing, 100142, China.

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https://jhoonline.biomedcentral.com/articles/10.1186/s13045-
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http://dx.doi.org/10.1186/s13045-019-0702-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376656PMC
February 2019

Connexin43 mutations linked to skin disease have augmented hemichannel activity.

Sci Rep 2019 01 10;9(1):19. Epub 2019 Jan 10.

Department of Physiology and Biophysics, Stony Brook University, Stony Brook, NY, 11794, USA.

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http://www.nature.com/articles/s41598-018-37221-2
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http://dx.doi.org/10.1038/s41598-018-37221-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328547PMC
January 2019

Revealing a human p53 universe.

Nucleic Acids Res 2018 09;46(16):8153-8167

Genome Integrity & Structural Biology Laboratory, National Institute of Environmental Health Sciences/National Institutes of Health, Research Triangle Park, NC 27709, USA.

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http://dx.doi.org/10.1093/nar/gky720DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6144829PMC
September 2018

Mir-22-3p Enhances the Chemosensitivity of Gastrointestinal Stromal Tumor Cell Lines to Cisplatin through PTEN/PI3K/Akt Pathway.

Iran J Allergy Asthma Immunol 2018 Aug 12;17(4):318-325. Epub 2018 Aug 12.

Department of General Surgery, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, China.

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http://dx.doi.org/10.18502/ijaai.v17i4.91DOI Listing
August 2018

Loss of Glis3 causes dysregulation of retrotransposon silencing and germ cell demise in fetal mouse testis.

Sci Rep 2018 06 25;8(1):9662. Epub 2018 Jun 25.

Reproductive Developmental Biology Laboratory, National Institute of Environmental Health Sciences, Durham, NC, USA.

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http://dx.doi.org/10.1038/s41598-018-27843-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6018429PMC
June 2018

Mediator complex component MED13 regulates zygotic genome activation and is required for postimplantation development in the mouse.

Biol Reprod 2018 04;98(4):449-464

Reproductive and Developmental Biology Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina, USA.

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http://dx.doi.org/10.1093/biolre/ioy004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279059PMC
April 2018

BI2536, a potent and selective inhibitor of polo-like kinase 1, in combination with cisplatin exerts synergistic effects on gastric cancer cells.

Int J Oncol 2018 Mar 25;52(3):804-814. Epub 2018 Jan 25.

Department of Critical Care Medicine, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, Shandong 250021, P.R. China.

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http://www.spandidos-publications.com/10.3892/ijo.2018.4255
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http://dx.doi.org/10.3892/ijo.2018.4255DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5807034PMC
March 2018

Discovery of novel potent HCV NS5B polymerase non-nucleoside inhibitors bearing a fused benzofuran scaffold.

Bioorg Med Chem Lett 2018 03 31;28(5):963-968. Epub 2018 Jan 31.

Presidio Pharmaceuticals, Inc., 1700 Owens Street, Suite 184, San Francisco, CA 94158, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2018.01.029DOI Listing
March 2018

miR-135b-5p promotes gastric cancer progression by targeting CMTM3.

Int J Oncol 2018 Feb 11;52(2):589-598. Epub 2017 Dec 11.

Department of General Surgery, Shandong Provincial Hospital Affiliated to Shandong University, Ji'nan, Shandong, P.R. China.

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http://dx.doi.org/10.3892/ijo.2017.4222DOI Listing
February 2018

The screening and analysis of protein signatures and signaling associated with chemoresistance based on Protein Pathway Array technology in gastric cancer.

Oncol Rep 2018 Jan 6;39(1):307-315. Epub 2017 Nov 6.

Department of Critical Care Medicine, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, Shandong 250021, P.R. China.

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http://www.spandidos-publications.com/10.3892/or.2017.6078
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http://dx.doi.org/10.3892/or.2017.6078DOI Listing
January 2018

miR-30 decreases multidrug resistance in human gastric cancer cells by modulating cell autophagy.

Exp Ther Med 2018 Jan 23;15(1):599-605. Epub 2017 Oct 23.

Department of Gastrointestinal Surgery, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, Shandong 250021, P.R. China.

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http://dx.doi.org/10.3892/etm.2017.5354DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5763658PMC
January 2018

Putative genomic characteristics of BRAF V600K versus V600E cutaneous melanoma.

Melanoma Res 2017 12;27(6):527-535

Biostatistics and Computational Biology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, Durham, North Carolina, USA.

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http://Insights.ovid.com/crossref?an=00008390-201712000-0000
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http://dx.doi.org/10.1097/CMR.0000000000000388DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5669042PMC
December 2017

LncRNA ZEB1-AS1 predicts unfavorable prognosis in gastric cancer.

Surg Oncol 2017 Dec 30;26(4):527-534. Epub 2017 Sep 30.

Department of General Surgery, Shandong Provincial Hospital Affiliated to Shandong University, NO.324 Jingwuweiqi Road, Jinan City 250021, Shandong Province, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.suronc.2017.09.008DOI Listing
December 2017

Compression-rate-dependent nonlinear mechanics of normal and impaired porcine knee joints.

BMC Musculoskelet Disord 2017 Nov 14;18(1):447. Epub 2017 Nov 14.

Department of Mechanical and Manufacturing Engineering, University of Calgary, 2500 University Drive, N.W, Calgary, AB, T2N 1N4, Canada.

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http://dx.doi.org/10.1186/s12891-017-1805-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5686835PMC
November 2017

Clinicopathological features and prognostic validity of WHO grading classification of SI-NENs.

BMC Cancer 2017 Aug 4;17(1):521. Epub 2017 Aug 4.

Department of Gastroenterology, The First Affiliated Hospital, Sun Yat-sen University, No.58 Zhongshan II Road, Yuexiu District, Guangzhou, 510080, China.

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http://dx.doi.org/10.1186/s12885-017-3490-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5543548PMC
August 2017

A comprehensive genomic pan-cancer classification using The Cancer Genome Atlas gene expression data.

BMC Genomics 2017 07 3;18(1):508. Epub 2017 Jul 3.

Biostatistics and Computational Biology Branch, National Institute of Environmental Health Sciences, NIH, Durham, NC, 27709, USA.

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http://dx.doi.org/10.1186/s12864-017-3906-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5496318PMC
July 2017

Sleep Apnea and Hypoventilation in Patients with Down Syndrome: Analysis of 144 Polysomnogram Studies.

Children (Basel) 2017 Jun 30;4(7). Epub 2017 Jun 30.

Department of Neurology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.

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http://dx.doi.org/10.3390/children4070055DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5532547PMC
June 2017

Upregulation of CD147 promotes cell invasion, epithelial-to-mesenchymal transition and activates MAPK/ERK signaling pathway in colorectal cancer.

Int J Clin Exp Pathol 2014 15;7(11):7432-41. Epub 2014 Oct 15.

Department of Gastrointestinal Surgery, Provincial Hospital Affiliated to Shandong University Jinan, Shandong, China.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4270601PMC
April 2017

Haploinsufficiency of SIRT1 Enhances Glutamine Metabolism and Promotes Cancer Development.

Curr Biol 2017 Feb 2;27(4):483-494. Epub 2017 Feb 2.

Signal Transduction Laboratory, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cub.2016.12.047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5319916PMC
February 2017

The novel p53 target TNFAIP8 variant 2 is increased in cancer and offsets p53-dependent tumor suppression.

Cell Death Differ 2017 01 11;24(1):181-191. Epub 2016 Nov 11.

Immunity, Inflammation, and Disease Laboratory, National Institute of Environmental Health Sciences, NIH, Research Triangle Park, NC 27709, USA.

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http://www.nature.com/articles/cdd2016130
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http://dx.doi.org/10.1038/cdd.2016.130DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5260499PMC
January 2017

Up-regulation of VEZT by small activating RNA inhibits the proliferation, invasion and migration of gastric cancer cells.

Biochem Biophys Res Commun 2017 Jan 14;482(4):542-548. Epub 2016 Nov 14.

Department of Gastrointestinal Surgery, Shandong Provincial Hospital Affiliated to Shandong University, Jinan 250000, Shandong, China. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2016.11.071DOI Listing
January 2017

The Diagnostic Efficacy and Biological Effects of microRNA-29b for Colon Cancer.

Technol Cancer Res Treat 2016 12 14;15(6):772-779. Epub 2015 Oct 14.

Department of General Surgery, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, China

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http://dx.doi.org/10.1177/1533034615604797DOI Listing
December 2016

miR-218 suppresses gastric cancer cell proliferation and invasion via regulation of angiopoietin-2.

Exp Ther Med 2016 Dec 11;12(6):3837-3842. Epub 2016 Nov 11.

Department of Gastrointestinal Surgery, School of Medicine, Shandong University, Jinan, Shandong 250012, P.R. China; Department of General Surgery, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, Shandong 250021, P.R. China.

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http://dx.doi.org/10.3892/etm.2016.3893DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5228446PMC
December 2016

Discovery of ravidasvir (PPI-668) as a potent pan-genotypic HCV NS5A inhibitor.

Bioorg Med Chem Lett 2016 09 29;26(18):4508-4512. Epub 2016 Jul 29.

Presidio Pharmaceuticals, Inc., 1700 Owens Street, Suite 585, San Francisco, CA 94158, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2016.07.066DOI Listing
September 2016

The Phosphoinosotide 3-Kinase Catalytic Subunit p110α is Required for Normal Lens Growth.

Invest Ophthalmol Vis Sci 2016 06;57(7):3145-51

Department of Physiology and Biophysics Stony Brook University, Stony Brook, New York, United States.

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http://iovs.arvojournals.org/article.aspx?doi=10.1167/iovs.1
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http://dx.doi.org/10.1167/iovs.16-19607DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4928694PMC
June 2016

Deficiency of the placenta- and yolk sac-specific tristetraprolin family member ZFP36L3 identifies likely mRNA targets and an unexpected link to placental iron metabolism.

Development 2016 Apr 7;143(8):1424-33. Epub 2016 Mar 7.

Laboratory of Signal Transduction, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA Departments of Medicine and Biochemistry, Duke University Medical Center, Durham, NC 27710, USA

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http://dx.doi.org/10.1242/dev.130369DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4852513PMC
April 2016

Overexpression of eIF4E in colorectal cancer patients is associated with liver metastasis.

Onco Targets Ther 2016 19;9:815-22. Epub 2016 Feb 19.

Department of Gastrointestinal Surgery, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, Shandong, People's Republic of China.

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http://dx.doi.org/10.2147/OTT.S98330DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4767060PMC
March 2016

ENmix: a novel background correction method for Illumina HumanMethylation450 BeadChip.

Nucleic Acids Res 2016 Feb 17;44(3):e20. Epub 2015 Sep 17.

Epidemiology Branch, National Institute of Environmental Health Sciences, NIH, Research Triangle Park, NC, USA Laboratory of Molecular Carcinogenesis, National Institute of Environmental Health Sciences, NIH, Research Triangle Park, NC, USA

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http://dx.doi.org/10.1093/nar/gkv907DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756845PMC
February 2016

Long noncoding RNAs as potential biomarkers in gastric cancer: Opportunities and challenges.

Cancer Lett 2016 Feb 11;371(1):62-70. Epub 2015 Nov 11.

Department of Gastrointestinal Surgery, Shandong Provincial Hospital Affiliated to Shandong University, Jinan 250021, China.

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http://dx.doi.org/10.1016/j.canlet.2015.11.011DOI Listing
February 2016

Connexin26 Mutations Causing Palmoplantar Keratoderma and Deafness Interact with Connexin43, Modifying Gap Junction and Hemichannel Properties.

J Invest Dermatol 2016 Jan;136(1):225-235

Department of Physiology and Biophysics, Stony Brook University, Stony Brook, New York, USA. Electronic address:

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http://dx.doi.org/10.1038/JID.2015.389DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4731051PMC
January 2016

Strain-rate-dependent non-linear tensile properties of the superficial zone of articular cartilage.

Connect Tissue Res 2015 Nov 20;56(6):469-76. Epub 2015 Aug 20.

a Department of Mechanical and Manufacturing Engineering , University of Calgary , Calgary , Alberta , Canada.

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http://www.tandfonline.com/doi/full/10.3109/03008207.2015.10
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http://dx.doi.org/10.3109/03008207.2015.1066779DOI Listing
November 2015

Hypoxia-inducible factor-1α and semaphorin4D genes involved with tumor-associated macrophage-induced metastatic behavior and clinical significance in colon cancer.

Chin Med J (Engl) 2014 ;127(20):3568-75

Department of Gastrointestinal Surgery, Shandong Provincial Hospital affiliated to Shandong University, Jinan, Shandong 250021, China. Email:

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August 2015

Expression of tumor necrosis factor α-induced protein 8 is upregulated in human gastric cancer and regulates cell proliferation, invasion and migration.

Mol Med Rep 2015 Aug 27;12(2):2636-42. Epub 2015 Apr 27.

Department of Gastrointestinal Surgery, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, Shandong 250021, P.R. China.

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https://www.spandidos-publications.com/10.3892/mmr.2015.3690
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http://dx.doi.org/10.3892/mmr.2015.3690DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4464344PMC
August 2015

microRNA-20a enhances the epithelial-to-mesenchymal transition of colorectal cancer cells by modulating matrix metalloproteinases.

Exp Ther Med 2015 Aug 3;10(2):683-688. Epub 2015 Jun 3.

Department of Gastrointestinal Surgery, Provincial Hospital Affiliated to Shandong University, Jinan, Shandong 250021, P.R. China.

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http://dx.doi.org/10.3892/etm.2015.2538DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4509132PMC
August 2015

Toward predicting metastatic progression of melanoma based on gene expression data.

Pigment Cell Melanoma Res 2015 Jul 24;28(4):453-63. Epub 2015 Apr 24.

Biostatistics and Computational Biology Branch, National Institute of Environmental Health Sciences, NIH, Research Triangle Park, NC, USA.

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http://dx.doi.org/10.1111/pcmr.12374DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4469521PMC
July 2015

MiR-492 is functionally involved in Oxaliplatin resistance in colon cancer cells LS174T via its regulating the expression of CD147.

Mol Cell Biochem 2015 Jul 11;405(1-2):73-9. Epub 2015 Apr 11.

Department of Gastrointestinal Surgery, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, People's Republic of China,

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http://link.springer.com/content/pdf/10.1007/s11010-015-2397
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http://link.springer.com/10.1007/s11010-015-2397-z
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http://dx.doi.org/10.1007/s11010-015-2397-zDOI Listing
July 2015

Focal cartilage defect compromises fluid-pressure dependent load support in the knee joint.

Int J Numer Method Biomed Eng 2015 Jun 14;31(6). Epub 2015 Apr 14.

Department of Mechanical and Manufacturing Engineering, University of Calgary, 2500 University Drive, N.W., Calgary, Alberta, T2N 1N4, Canada.

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http://doi.wiley.com/10.1002/cnm.2713
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http://dx.doi.org/10.1002/cnm.2713DOI Listing
June 2015

Aberrant connexin26 hemichannels underlying keratitis-ichthyosis-deafness syndrome are potently inhibited by mefloquine.

J Invest Dermatol 2015 Apr 17;135(4):1033-1042. Epub 2014 Sep 17.

Department of Physiology and Biophysics, Stony Brook University, Stony Brook, New York, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S0022202X153718
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http://dx.doi.org/10.1038/jid.2014.408DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363291PMC
April 2015

Post-transcriptional regulation of transcript abundance by a conserved member of the tristetraprolin family in Candida albicans.

Mol Microbiol 2015 Mar 30;95(6):1036-53. Epub 2015 Jan 30.

Laboratory of Signal Transduction, National Institute of Environmental Health Sciences, Research Triangle Park, NC, 27709, USA.

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http://dx.doi.org/10.1111/mmi.12913DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4557868PMC
March 2015

Visco-hyperelastic constitutive modeling of soft tissues based on short and long-term internal variables.

Biomed Eng Online 2015 Mar 30;14:29. Epub 2015 Mar 30.

Department of Mechanical and Manufacturing Engineering, University of Calgary, 2500 University Drive NW, Calgary, Alberta, T2N 1N4, Canada.

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http://www.biomedical-engineering-online.com/content/14/1/29
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http://dx.doi.org/10.1186/s12938-015-0023-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4407883PMC
March 2015

The Drosophila Tis11 protein and its effects on mRNA expression in flies.

J Biol Chem 2014 Dec 23;289(51):35042-60. Epub 2014 Oct 23.

From the Laboratories of Signal Transduction, the Departments of Medicine and Biochemistry, Duke University Medical Center, Durham, North Carolina 27710

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http://dx.doi.org/10.1074/jbc.M114.593491DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4271196PMC
December 2014

Discovery of functionalized bisimidazoles bearing cyclic aliphatic-phenyl motifs as HCV NS5A inhibitors.

Bioorg Med Chem Lett 2014 Dec 22;24(24):5731-5737. Epub 2014 Oct 22.

Presidio Pharmaceuticals, Inc., 1700 Owens Street, Suite 585, San Francisco, CA 94158, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2014.10.057DOI Listing
December 2014

Potent bisimidazole-based HCV NS5A inhibitors bearing annulated tricyclic motifs.

Bioorg Med Chem Lett 2014 Dec 22;24(24):5738-5742. Epub 2014 Oct 22.

Presidio Pharmaceuticals, Inc., 1700 Owens Street, Suite 585, San Francisco, CA 94158, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2014.10.056DOI Listing
December 2014

Connexin 46 (cx46) gap junctions provide a pathway for the delivery of glutathione to the lens nucleus.

J Biol Chem 2014 Nov 7;289(47):32694-702. Epub 2014 Oct 7.

From the Department of Biological and Vision Sciences and the Graduate Center for Vision Research, State University of New York College of Optometry, New York, New York 10036 and

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http://dx.doi.org/10.1074/jbc.M114.597898DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4239621PMC
November 2014

IUTA: a tool for effectively detecting differential isoform usage from RNA-Seq data.

BMC Genomics 2014 Oct 6;15:862. Epub 2014 Oct 6.

Biostatistics Branch, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA.

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http://dx.doi.org/10.1186/1471-2164-15-862DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4195885PMC
October 2014

Transcriptional repression by the BRG1-SWI/SNF complex affects the pluripotency of human embryonic stem cells.

Stem Cell Reports 2014 Sep 14;3(3):460-74. Epub 2014 Aug 14.

Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, Shanghai 200241, China. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2014.07.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4266000PMC
September 2014

Novel DNA motif binding activity observed in vivo with an estrogen receptor α mutant mouse.

Mol Endocrinol 2014 Jun 8;28(6):899-911. Epub 2014 Apr 8.

Receptor Biology (S.C.H., W.W., K.J.H., B.P., K.S.K.), Laboratory of Reproductive and Developmental Toxicology, Biostatistics Branch (L.L.), Integrative Bioinformatics (S.A.G., D.F.), Laboratory of Structural Biology (L.C.P.), National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina 27709; Department of Molecular and Cellular Biology (C.A.R., R.B.L., F.J.D.), Baylor College of Medicine, Houston, Texas 77030; and Department of Molecular Biology of the Cell (G.S.), German Cancer Research Center, 69121 Heidelberg, Germany.

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http://dx.doi.org/10.1210/me.2014-1051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4042070PMC
June 2014

VEZT, a novel putative tumor suppressor, suppresses the growth and tumorigenicity of gastric cancer.

PLoS One 2013 17;8(9):e74409. Epub 2013 Sep 17.

Department of Gastrointestinal Surgery, Provincial Hospital Affiliated to Shandong University, Jinan, Shandong, China.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3775783PMC
May 2014

[Correlation and clinical significance of expressions of HIF-1α and Sema4D in colorectal carcinoma tissues].

Zhonghua Wei Chang Wai Ke Za Zhi 2014 Apr;17(4):388-92

Department of Gastrointestinal Surgery, Provincial Hospital, Shandong University, Jinan 250021, China.

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April 2014

T-KDE: a method for genome-wide identification of constitutive protein binding sites from multiple ChIP-seq data sets.

BMC Genomics 2014 Jan 15;15:27. Epub 2014 Jan 15.

Biostatistics Branch, National Institute of Environmental Health Sciences, Research Triangle Park, Morrisville, NC 27709, USA.

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http://dx.doi.org/10.1186/1471-2164-15-27DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3903014PMC
January 2014

PAVIS: a tool for Peak Annotation and Visualization.

Bioinformatics 2013 Dec 4;29(23):3097-9. Epub 2013 Sep 4.

Biostatistics Branch and the Integrative Bioinformatics Group, National Institute of Environmental Health Sciences, Durham, NC 27709, USA.

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http://dx.doi.org/10.1093/bioinformatics/btt520DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3834791PMC
December 2013

The effects of age on lens transport.

Invest Ophthalmol Vis Sci 2013 Nov 1;54(12):7174-87. Epub 2013 Nov 1.

Department of Physiology & Biophysics, SUNY at Stony Brook, Stony Brook, New York.

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http://iovs.arvojournals.org/article.aspx?doi=10.1167/iovs.1
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http://dx.doi.org/10.1167/iovs.13-12593DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3816616PMC
November 2013

Inter-insertional distance is a poor correlate for ligament load: analysis from in vivo gait kinetics data.

J Biomech 2013 Sep 17;46(13):2264-70. Epub 2013 Jul 17.

Department of Biomedical Engineering, Faculty of Engineering, University of Calgary, Calgary, Alberta, Canada.

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http://dx.doi.org/10.1016/j.jbiomech.2013.06.023DOI Listing
September 2013

Characterization of constitutive CTCF/cohesin loci: a possible role in establishing topological domains in mammalian genomes.

BMC Genomics 2013 Aug 14;14:553. Epub 2013 Aug 14.

Biostatistics Branch, National Institute of Environmental Health Sciences, Research Triangle Park, Durham, NC 27709, USA.

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http://dx.doi.org/10.1186/1471-2164-14-553DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3765723PMC
August 2013

Posttranscriptional regulation of cell-cell interaction protein-encoding transcripts by Zfs1p in Schizosaccharomyces pombe.

Mol Cell Biol 2012 Oct 20;32(20):4206-14. Epub 2012 Aug 20.

Laboratory of Signal Transduction, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina, USA.

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http://dx.doi.org/10.1128/MCB.00325-12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3457339PMC
October 2012

Discovery of a novel melanin concentrating hormone receptor 1 (MCHR1) antagonist with reduced hERG inhibition.

Bioorg Med Chem Lett 2012 Jun 7;22(11):3781-5. Epub 2012 Apr 7.

Department of Chemistry, Amgen San Francisco, South San Francisco, CA 94080, USA.

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http://dx.doi.org/10.1016/j.bmcl.2012.04.006DOI Listing
June 2012

Research resource: whole-genome estrogen receptor α binding in mouse uterine tissue revealed by ChIP-seq.

Mol Endocrinol 2012 May 22;26(5):887-98. Epub 2012 Mar 22.

Receptor Biology, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina 27709, USA.

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http://dx.doi.org/10.1210/me.2011-1311DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3355558PMC
May 2012

Discovery of a new class of ghrelin receptor antagonists.

Bioorg Med Chem Lett 2012 Mar 14;22(5):2046-51. Epub 2012 Jan 14.

Amgen Inc., 1120 Veterans Boulevard, ASF2-3, South San Francisco, CA 94080, USA.

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March 2012

ART: a next-generation sequencing read simulator.

Bioinformatics 2012 Feb 23;28(4):593-4. Epub 2011 Dec 23.

Biostatistics Branch, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA.

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http://dx.doi.org/10.1093/bioinformatics/btr708DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3278762PMC
February 2012

Discovery and characterization of a potent and selective antagonist of melanin-concentrating hormone receptor 2.

Bioorg Med Chem Lett 2012 Jan 9;22(1):363-6. Epub 2011 Nov 9.

Amgen Inc., 1120 Veterans Boulevard, ASF2-3, South San Francisco, CA 94080, USA.

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http://dx.doi.org/10.1016/j.bmcl.2011.10.125DOI Listing
January 2012

coMOTIF: a mixture framework for identifying transcription factor and a coregulator motif in ChIP-seq data.

Bioinformatics 2011 Oct 19;27(19):2625-32. Epub 2011 Jul 19.

Biostatistics Branch, National Institute of Environmental Health Sciences, NIH, Research Triangle Park, NC 27709, USA.

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http://dx.doi.org/10.1093/bioinformatics/btr397DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3179653PMC
October 2011

Efficiently identifying genome-wide changes with next-generation sequencing data.

Nucleic Acids Res 2011 Oct 29;39(19):e130. Epub 2011 Jul 29.

Biostatistics Branch, National Institute of Environmental Health Sciences, RTP, NC 27709, USA.

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http://dx.doi.org/10.1093/nar/gkr592DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3201882PMC
October 2011

Down-regulation of VEZT gene expression in human gastric cancer involves promoter methylation and miR-43c.

Biochem Biophys Res Commun 2011 Jan 13;404(2):622-7. Epub 2010 Dec 13.

Department of Gastrointestinal Surgery, Shandong Provincial Hospital, Shandong University, Jinan 250021, China.

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January 2011

Comparing the effects of Bassini versus tension-free hernioplasty: 3 years' follow-up.

Front Med China 2010 Dec 25;4(4):463-8. Epub 2010 Nov 25.

Division of Gastrointestinal Surgery, Affiliated Provincial Hospital of Shandong University, Jinwu Road 324, Jinan, 250021, China.

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http://dx.doi.org/10.1007/s11684-010-0050-5DOI Listing
December 2010

Pausing of RNA polymerase II disrupts DNA-specified nucleosome organization to enable precise gene regulation.

Cell 2010 Nov;143(4):540-51

Laboratory of Molecular Carcinogenesis, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC 27709, USA.

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http://dx.doi.org/10.1016/j.cell.2010.10.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2991113PMC
November 2010

DNA methylation prevents CTCF-mediated silencing of the oncogene BCL6 in B cell lymphomas.

J Exp Med 2010 Aug 23;207(9):1939-50. Epub 2010 Aug 23.

Laboratory of Molecular Carcinogenesis, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA.

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http://dx.doi.org/10.1084/jem.20100204DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2931164PMC
August 2010

Identification of piperazine-bisamide GHSR antagonists for the treatment of obesity.

Bioorg Med Chem Lett 2010 Mar 20;20(5):1758-62. Epub 2010 Jan 20.

Amgen Inc. 1120 Veterans Boulevard, South San Francisco, CA 94080, USA.

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http://dx.doi.org/10.1016/j.bmcl.2010.01.043DOI Listing
March 2010

Estrogen-mediated regulation of Igf1 transcription and uterine growth involves direct binding of estrogen receptor alpha to estrogen-responsive elements.

J Biol Chem 2010 Jan 17;285(4):2676-85. Epub 2009 Nov 17.

Receptor Biology Section, Laboratory of Reproductive and Developmental Toxicology, NIEHS, National Institutes of Health, Research Triangle Park, North Carolina 27709, USA.

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http://dx.doi.org/10.1074/jbc.M109.043471DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2807324PMC
January 2010

Interaction between Connexin50 and mitogen-activated protein kinase signaling in lens homeostasis.

Mol Biol Cell 2009 May 25;20(10):2582-92. Epub 2009 Mar 25.

Department of Physiology and Biophysics, Stony Brook University, Stony Brook, NY 11794-8661, USA.

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http://www.molbiolcell.org/doi/10.1091/mbc.e08-12-1257
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http://dx.doi.org/10.1091/mbc.e08-12-1257DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2682599PMC
May 2009

Coexpression of cyclooxygenase-2 and vascular endothelial growth factor in gastrointestinal stromal tumor: possible relations to pathological parameters and clinical behavior.

Hepatogastroenterology 2008 Nov-Dec;55(88):2012-5

Department of Surgery, Shandong Provincial Hospital, Shandong University, P.R. China.

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April 2009

The cataract causing Cx50-S50P mutant inhibits Cx43 and intercellular communication in the lens epithelium.

Exp Cell Res 2009 Apr 30;315(6):1063-75. Epub 2009 Jan 30.

Department of Physiology and Biophysics, State University of New York, T5-147, Basic Science Tower, Stony Brook, NY 11794-8661, USA.

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http://dx.doi.org/10.1016/j.yexcr.2009.01.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2670955PMC
April 2009

GADEM: a genetic algorithm guided formation of spaced dyads coupled with an EM algorithm for motif discovery.

Authors:
Leping Li

J Comput Biol 2009 Feb;16(2):317-29

Biostatistics Branch, National Institute of Environmental Health Sciences, NIH, Research Triangle Park, NC 27709, USA.

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http://dx.doi.org/10.1089/cmb.2008.16TTDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2756050PMC
February 2009