Publications by authors named "Leontien Bosch"

15Publications

Ultrarapid Delayed Rectifier K Channelopathies in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes.

Front Cell Dev Biol 2020 28;8:536. Epub 2020 Jul 28.

Department of Medical Biology, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands.

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http://dx.doi.org/10.3389/fcell.2020.00536DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7399090PMC
July 2020

Gene replacement ameliorates deficits in mouse and human models of cyclin-dependent kinase-like 5 disorder.

Brain 2020 03;143(3):811-832

Gene Therapy, Section of Neuroscience, Department of Brain Sciences, Faculty of Medicine, Imperial College London, Hammersmith Campus, London W12 0NN, UK.

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http://dx.doi.org/10.1093/brain/awaa028DOI Listing
March 2020

Methylation-mediated repression of PRDM14 contributes to apoptosis evasion in HPV-positive cancers.

Carcinogenesis 2014 Nov 18;35(11):2611-8. Epub 2014 Sep 18.

Department of Pathology, Unit of Molecular Pathology, VU University Medical Center, Amsterdam, The Netherlands and

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http://dx.doi.org/10.1093/carcin/bgu197DOI Listing
November 2014

Differential in vitro immortalization capacity of eleven (probable) [corrected] high-risk human papillomavirus types.

J Virol 2014 Feb 20;88(3):1714-24. Epub 2013 Nov 20.

Department of Pathology, Unit of Molecular Pathology, VU University Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1128/JVI.02859-13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3911618PMC
February 2014

Focal aberrations indicate EYA2 and hsa-miR-375 as oncogene and tumor suppressor in cervical carcinogenesis.

Genes Chromosomes Cancer 2013 Jan 14;52(1):56-68. Epub 2012 Sep 14.

Department of Pathology, VU University Medical Center, Amsterdam, The Netherlands.

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http://doi.wiley.com/10.1002/gcc.22006
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http://dx.doi.org/10.1002/gcc.22006DOI Listing
January 2013

The functional role of Notch signaling in HPV-mediated transformation is dose-dependent and linked to AP-1 alterations.

Cell Oncol (Dordr) 2012 Apr 24;35(2):77-84. Epub 2012 Jan 24.

Department of Pathology, Unit of Molecular Pathology, VU University Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1007/s13402-011-0062-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3306567PMC
April 2012

CXCR3 antagonists: quaternary ammonium salts equipped with biphenyl- and polycycloaliphatic-anchors.

Bioorg Med Chem 2011 Jun 24;19(11):3384-93. Epub 2011 Apr 24.

Leiden/Amsterdam Center for Drug Research, Division of Medicinal Chemistry, Faculty of Sciences, VU University Amsterdam, De Boelelaan 1083, 1081 HV Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.bmc.2011.04.035DOI Listing
June 2011

Exploring a pocket for polycycloaliphatic groups in the CXCR3 receptor with the aid of a modular synthetic strategy.

Bioorg Med Chem Lett 2009 Apr 27;19(8):2252-7. Epub 2009 Feb 27.

Division of Medicinal Chemistry, Faculty of Sciences, Leiden/Amsterdam Center for Drug Research, VU University Amsterdam, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.bmcl.2009.02.093DOI Listing
April 2009

Nonpeptidergic allosteric antagonists differentially bind to the CXCR2 chemokine receptor.

J Pharmacol Exp Ther 2009 May 3;329(2):783-90. Epub 2009 Feb 3.

Leiden/Amsterdam Center of Drug Research, Division of Medicinal Chemistry, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1124/jpet.108.148387DOI Listing
May 2009

Synthesis and structure-activity relationships of 3H-quinazolin-4-ones and 3H-pyrido[2,3-d]pyrimidin-4-ones as CXCR3 receptor antagonists.

Arch Pharm (Weinheim) 2007 Jun;340(6):281-91

Leiden/Amsterdam Center for Drug Research (LACDR), Division of Medicinal Chemistry, Faculty of Sciences, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.

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http://dx.doi.org/10.1002/ardp.200700037DOI Listing
June 2007