Leonor Correia Guedes

Instituto de Medicina Molecular, Lisbon, Portugal; Laboratory of Clinical Pharmacology and Therapeutics, Faculdade de Medicina, Universidade de Lisboa, Portugal; CNS - Campus Neurológico Sénior, Torres Vedras, Portugal. Electronic address:

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July 2019

LRP10 genetic variants in familial Parkinson's disease and dementia with Lewy bodies: a genome-wide linkage and sequencing study.

Authors:

Marialuisa Quadri Wim Mandemakers Martyna M Grochowska Roy Masius Hanneke Geut Edito Fabrizio Guido J Breedveld Demy Kuipers Michelle Minneboo Leonie J M Vergouw Ana Carreras Mascaro Ekaterina Yonova-Doing Erik Simons Tianna Zhao Alessio B Di Fonzo Hsiu-Chen Chang Piero Parchi Marta Melis Leonor Correia Guedes Chiara Criscuolo Astrid Thomas Rutger W W Brouwer Daphne Heijsman Angela M T Ingrassia Giovanna Calandra Buonaura Janneke P Rood Sabina Capellari Annemieke J Rozemuller Marianna Sarchioto Hsin Fen Chien Nicola Vanacore Simone Olgiati Yah-Huei Wu-Chou Tu-Hsueh Yeh Agnita J W Boon Susanne E Hoogers Mehrnaz Ghazvini Arne S IJpma Wilfred F J van IJcken Marco Onofrj Paolo Barone David J Nicholl Andreas Puschmann Michele De Mari Anneke J Kievit Egberto Barbosa Giuseppe De Michele Danielle Majoor-Krakauer John C van Swieten Frank J de Jong Joaquim J Ferreira Giovanni Cossu Chin-Song Lu Giuseppe Meco Pietro Cortelli Wilma D J van de Berg Vincenzo Bonifati

Lancet Neurol 2018 07 7;17(7):597-608. Epub 2018 Jun 7.

Department of Clinical Genetics, Erasmus Medical Center, Rotterdam, Netherlands. Electronic address:

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July 2018

Posttranslational modifications of blood-derived alpha-synuclein as biochemical markers for Parkinson's disease.

Authors:

Hugo Vicente Miranda Rafaela Cássio Leonor Correia-Guedes Marcos António Gomes Ana Chegão Elisa Miranda Tiago Soares Miguel Coelho Mário Miguel Rosa Joaquim J Ferreira Tiago Fleming Outeiro

Sci Rep 2017 10 20;7(1):13713. Epub 2017 Oct 20.

CEDOC, Chronic Diseases Research Centre, NOVA Medical School|Faculdade de Ciências Médicas, Universidade NOVA de Lisboa, Campo dos Mártires da Pátria, 130, 1169-056, Lisboa, Portugal.

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October 2017

Serum lipid alterations in GBA-associated Parkinson's disease.

Authors:

Leonor Correia Guedes Robin Barry Chan Marcos António Gomes Vasco A Conceição Raquel Bouça Machado Tiago Soares Yimeng Xu Paulo Gaspar Joao André Carriço Roy N Alcalay Joaquim J Ferreira Tiago Fleming Outeiro Gabriel Miltenberger-Miltenyi

Parkinsonism Relat Disord 2017 Nov 1;44:58-65. Epub 2017 Sep 1.

Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal; Laboratorio de Genetica, Faculty of Medicine, University of Lisbon, Portugal; Portuguese Reference Center of Lysosomal Storage Diseases, Hospital Senhora de Oliveira Guimaraes / University of Minho, Braga, Portugal. Electronic address:

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November 2017

Speech and Voice Response to a Levodopa Challenge in Late-Stage Parkinson's Disease.

Authors:

Margherita Fabbri Isabel Guimarães Rita Cardoso Miguel Coelho Leonor Correia Guedes Mario M Rosa Catarina Godinho Daisy Abreu Nilza Gonçalves Angelo Antonini Joaquim J Ferreira

Front Neurol 2017 22;8:432. Epub 2017 Aug 22.

Faculty of Medicine, Instituto de Medicina Molecular, University of Lisbon, Lisbon, Portugal.

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August 2017

Clinical rating scale for pantothenate kinase-associated neurodegeneration: A pilot study.

Mov Disord 2017 Nov 28;32(11):1620-1630. Epub 2017 Aug 28.

Unit of Pediatric Movement Disorders, Hospital Sant Joan de Déu, Barcelona, Spain.

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November 2017

Neuromelanin magnetic resonance imaging of the substantia nigra in LRRK2-related Parkinson's disease.

Mov Disord 2017 09 7;32(9):1331-1333. Epub 2017 Jul 7.

Clinical Pharmachology Unit, Instituto de Medicina Molecular, Lisbon, Portugal.

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September 2017

Substantia Nigra Neuromelanin as an Imaging Biomarker of Disease Progression in Parkinson's Disease.

Authors:

Margherita Fabbri Sofia Reimão Miguel Carvalho Rita G Nunes Daisy Abreu Leonor Correia Guedes Raquel Bouça Patricia P Lobo Catarina Godinho Miguel Coelho Nilza C Gonçalves Mario Miguel Rosa Angelo Antonini Joaquim J Ferreira

J Parkinsons Dis 2017 ;7(3):491-501

Clinical Pharmacology Unit, Instituto de Medicina Molecular, Faculty of Medicine, University of Lisbon, Lisbon, Portugal.

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April 2018

Survival, Mortality, Causes and Places of Death in a European Huntington's Disease Prospective Cohort.

Authors:

Filipe Brogueira Rodrigues Daisy Abreu Joana Damásio Nilza Goncalves Leonor Correia-Guedes Miguel Coelho Joaquim J Ferreira

Mov Disord Clin Pract 2017 Sep-Oct;4(5):737-742. Epub 2017 May 26.

Clinical Pharmacology Unit Instituto de Medicina Molecular Lisbon Portugal.

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May 2017

Acute response of non-motor symptoms to subthalamic deep brain stimulation in Parkinson's disease.

Authors:

Margherita Fabbri Miguel Coelho Leonor Correia Guedes Mario M Rosa Daisy Abreu Nilza Gonçalves Angelo Antonini Joaquim J Ferreira

Parkinsonism Relat Disord 2017 Aug 8;41:113-117. Epub 2017 May 8.

Instituto de Medicina Molecular, Faculty of Medicine, University of Lisbon, Portugal; Neurology Service, Department of Neurosciences, Hospital Santa Maria, Lisbon, Portugal; Laboratory of Clinical Pharmacology and Therapeutics, Faculty of Medicine, University of Lisbon, Portugal. Electronic address:

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August 2017

Response of non-motor symptoms to levodopa in late-stage Parkinson's disease: Results of a levodopa challenge test.

Authors:

Margherita Fabbri Miguel Coelho Leonor Correia Guedes Ines Chendo Catarina Sousa Mario M Rosa Daisy Abreu Nilza Costa Catarina Godinho Angelo Antonini Joaquim J Ferreira

Parkinsonism Relat Disord 2017 06 7;39:37-43. Epub 2017 Feb 7.

Instituto de Medicina Molecular, Faculty of Medicine, University of Lisbon, Portugal; Department of Neurosciences, Hospital Santa Maria, Centro Hospitalar Lisboa Norte, Lisbon, Portugal; Laboratory of Clinical Pharmacology and Therapeutics, Faculty of Medicine, University of Lisbon, Portugal. Electronic address:

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June 2017

Disability in Activities of Daily Living and Severity of Dyskinesias Determine the Handicap of Parkinson's Disease Patients in Advanced Stage Selected to DBS.

Authors:

Miguel Coelho Daisy Abreu Leonor Correia-Guedes Patricia Pita Lobo Margherita Fabbri Catarina Godinho Josefa Domingos Luisa Albuquerque Vanda Freitas João Miguel Pereira Begona Cattoni Herculano Carvalho Sofia Reimão Mário M Rosa António Gonalves Ferreira Joaquim J Ferreira

J Parkinsons Dis 2017 ;7(2):255-261

Department of Neurosciences, Service of Neurology, Hospital Santa Maria, Lisbon, Portugal.

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January 2018

Clinical trials in palliative care: a systematic review of their methodological characteristics and of the quality of their reporting.

Authors:

Raquel Bouça-Machado Madalena Rosário Joana Alarcão Leonor Correia-Guedes Daisy Abreu Joaquim J Ferreira

BMC Palliat Care 2017 Jan 25;16(1):10. Epub 2017 Jan 25.

Clinical Pharmacology Unit, Instituto de Medicina Molecular, Faculty of Medicine, University of Lisbon, Avenue Professor Egas Moniz, 1649-028, Lisbon, Portugal.

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January 2017

Mutations in TMEM230 are not a common cause of Parkinson's disease.

Mov Disord 2017 02 16;32(2):302-304. Epub 2017 Jan 16.

Department of Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands.

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February 2017

Lack of evidence for a role of genetic variation in TMEM230 in the risk for Parkinson's disease in the Caucasian population.

Neurobiol Aging 2017 02 11;50:167.e11-167.e13. Epub 2016 Oct 11.

Department for Neurodegenerative Diseases, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany; German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany. Electronic address:

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February 2017

Musician's Dystonia as the Initial Presentation of Parkinson's Disease.

Authors:

Ana Castro Caldas Leonor Correia Guedes Joaquim J Ferreira Miguel Coelho

Mov Disord Clin Pract 2016 Nov-Dec;3(6):624-625. Epub 2016 Jun 6.

Department of Neurosciences, Service of Neurology Hospital de Santa Maria CHLN Lisbon Portugal.

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June 2016

Espresso Coffee for the Treatment of Somnolence in Parkinson's Disease: Results of n-of-1 Trials.

Authors:

Joaquim J Ferreira Tiago Mestre Leonor Correia Guedes Miguel Coelho Mário M Rosa Ana T Santos Márcio Barra Cristina Sampaio Olivier Rascol

Front Neurol 2016 8;7:27. Epub 2016 Mar 8.

Departments of Clinical Pharmacology and Neurosciences, University Hospital of Toulouse and Clinical Investigation Center INSERM CIC9302 and UMR825, University of Toulouse III , Toulouse , France.

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March 2016

Do patients with late-stage Parkinson's disease still respond to levodopa?

Authors:

Margherita Fabbri Miguel Coelho Daisy Abreu Leonor Correia Guedes Mario M Rosa Nilza Costa Angelo Antonini Joaquim J Ferreira

Parkinsonism Relat Disord 2016 05 26;26:10-6. Epub 2016 Feb 26.

Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Avenida Professor Egas Moniz, 1649-028, Lisboa, Portugal; Neurology Service, Department of Neurosciences, Hospital Santa Maria, Lisbon, Portugal; Laboratory of Clinical Pharmacology and Therapeutics, Faculty of Medicine, University of Lisbon, Portugal. Electronic address:

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May 2016

Quantitative Analysis Versus Visual Assessment of Neuromelanin MR Imaging for the Diagnosis of Parkinson's disease.

Authors:

Sofia Reimão Patrícia Pita Lobo Dulce Neutel Leonor Correia Guedes Miguel Coelho Mario M Rosa Joana Ferreira Daisy Abreu Nilza Gonçalves Carlos Morgado Rita G Nunes Jorge Campos Joaquim J Ferreira

J Parkinsons Dis 2015 ;5(3):561-7

Clinical Pharmacology Unit, Instituto de Medicina Molecular, University of Lisbon, Portugal.

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July 2016

Quantitative Analysis Versus Visual Assessment of Neuromelanin MR Imaging for the Diagnosis of Parkinson's disease.

Authors:

Sofia Reimão Patrícia Pita Lobo Dulce Neutel Leonor Correia Guedes Miguel Coelho Mario M Rosa Joana Ferreira Daisy Abreu Nilza Gonçalves Carlos Morgado Rita G Nunes Jorge Campos Joaquim J Ferreira

J Parkinsons Dis 2015 ;5(3):561-7

Clinical Pharmacology Unit, Instituto de Medicina Molecular, University of Lisbon, Portugal.

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July 2016

Eye of the Tiger Sign and Very Late Onset in Dentatorubral-Pallidoluysian Atrophy.

Authors:

Joana Morgado Sofia Reimão Miguel Coelho Mário M Rosa Joaquim J Ferreira Leonor Correia Guedes

Mov Disord Clin Pract 2015 Sep 22;2(3):313-315. Epub 2015 May 22.

Department of Neurology Hospital de Santa Maria Lisbon Portugal.

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September 2015

Substantia nigra neuromelanin-MR imaging differentiates essential tremor from Parkinson's disease.

Authors:

Sofia Reimão Patrícia Pita Lobo Dulce Neutel Leonor Correia Guedes Miguel Coelho Mário M Rosa Pedro Azevedo Joana Ferreira Daisy Abreu Nilza Gonçalves Rita G Nunes Jorge Campos Joaquim J Ferreira

Mov Disord 2015 Jun 11;30(7):953-9. Epub 2015 Mar 11.

Clinical Pharmacology Unit, Instituto de Medicina Molecular, Faculty of Medicine, University of Lisbon, Portugal.

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June 2015

An exome study of Parkinson's disease in Sardinia, a Mediterranean genetic isolate.

Neurogenetics 2015 Jan 8;16(1):55-64. Epub 2014 Oct 8.

Department of Clinical Genetics, Erasmus MC, PO Box 2040, 3000, CA, Rotterdam, The Netherlands.

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January 2015

STN-DBS does not change emotion recognition in advanced Parkinson's disease.

Authors:

Luisa Albuquerque Miguel Coelho Maurício Martins Leonor Correia Guedes Mário M Rosa Joaquim J Ferreira Maria Begoña Cattoni Herculano Carvalho A Gonçalves Ferreira Isabel Pavão Martins

Parkinsonism Relat Disord 2014 Feb 18;20(2):166-9. Epub 2013 Oct 18.

Language Research Laboratory, University of Lisbon, and Department of Clinical Neurosciences, Santa Maria Hospital, Lisbon, Portugal; Institute of Molecular Medicine and Faculty of Medicine, University of Lisbon, and Department of Clinical Neurosciences, Santa Maria Hospital, Lisbon, Portugal.

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February 2014