Publications by authors named "Leonie G Mikael"

27Publications

High folic acid consumption leads to pseudo-MTHFR deficiency, altered lipid metabolism, and liver injury in mice.

Am J Clin Nutr 2015 Mar 7;101(3):646-58. Epub 2015 Jan 7.

From the Departments of Human Genetics and Pediatrics, McGill University, and the Montreal Children's Hospital site of the McGill University Health Centre Research Institute, Montreal, Quebec, Canada (KEC, LGM, NL, LD, QW, and RR); Developmental Biology and Cancer Programme, Institute of Child Health, University College London, London, United Kingdom (K-YL and NDEG); the Division of Nutritional Sciences and Genomics, Cornell University, Ithaca, NY (OVM and MAC); and the Department of Mathematics and Statistics, McGill University, Montreal, Quebec, Canada (AB).

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http://dx.doi.org/10.3945/ajcn.114.086603DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4340065PMC
March 2015

Moderately high intake of folic acid has a negative impact on mouse embryonic development.

Birth Defects Res A Clin Mol Teratol 2013 Jan 2;97(1):47-52. Epub 2012 Nov 2.

Departments of Human Genetics and Pediatrics, McGill University, Montreal Children's Hospital Research Institute, Montreal, Quebec, Canada.

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http://dx.doi.org/10.1002/bdra.23092DOI Listing
January 2013

Low dietary folate and methylenetetrahydrofolate reductase deficiency may lead to pregnancy complications through modulation of ApoAI and IFN-γ in spleen and placenta, and through reduction of methylation potential.

Mol Nutr Food Res 2013 Apr 30;57(4):661-70. Epub 2012 Oct 30.

Department of Human Genetics, McGill University, Montreal Children's Hospital Research Institute, Montreal, QC, Canada.

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http://dx.doi.org/10.1002/mnfr.201200152DOI Listing
April 2013

Differential gene expression and methylation in the retinoid/PPARA pathway and of tumor suppressors may modify intestinal tumorigenesis induced by low folate in mice.

Mol Nutr Food Res 2013 Apr 24;57(4):686-97. Epub 2012 Sep 24.

Department of Human Genetics, Montreal Children's Hospital Research Institute, McGill University, Montreal, Canada.

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http://dx.doi.org/10.1002/mnfr.201200212DOI Listing
April 2013

Disturbed one-carbon metabolism causing adverse reproductive outcomes in mice is associated with altered expression of apolipoprotein AI and inflammatory mediators PPARα, interferon-γ, and interleukin-10.

J Nutr 2012 Mar 18;142(3):411-8. Epub 2012 Jan 18.

Department of Human Genetics, McGill University, Montreal Children's Hospital Research Institute, Montreal, QC, Canada.

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https://academic.oup.com/jn/article/142/3/411/4630834
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http://dx.doi.org/10.3945/jn.111.151753DOI Listing
March 2012

Low dietary choline and low dietary riboflavin during pregnancy influence reproductive outcomes and heart development in mice.

Am J Clin Nutr 2010 Apr 17;91(4):1035-43. Epub 2010 Feb 17.

Department of Human Genetics, McGill University, Montreal Children's Hospital Research Institute, Montreal, Canada.

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http://dx.doi.org/10.3945/ajcn.2009.28754DOI Listing
April 2010

Hyperhomocysteinemia is associated with hypertriglyceridemia in mice with methylenetetrahydrofolate reductase deficiency.

Mol Genet Metab 2009 Sep-Oct;98(1-2):187-94. Epub 2009 Jun 23.

Departments of Human Genetics and Pediatrics, McGill University, Montreal Children's Hospital, Que., Canada.

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http://dx.doi.org/10.1016/j.ymgme.2009.05.011DOI Listing
November 2009

Methylenetetrahydrofolate reductase deficiency and low dietary folate increase embryonic delay and placental abnormalities in mice.

Birth Defects Res A Clin Mol Teratol 2009 Jun;85(6):531-41

Department of Human Genetics, McGill University and Montreal Children's Hospital Research Institute, Montreal, Quebec H3Z 2Z3, Canada.

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http://doi.wiley.com/10.1002/bdra.20575
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http://dx.doi.org/10.1002/bdra.20575DOI Listing
June 2009

Homocysteine modulates the effect of simvastatin on expression of ApoA-I and NF-kappaB/iNOS.

Cardiovasc Res 2008 Oct 7;80(1):151-8. Epub 2008 Jun 7.

Department of Human Genetics, McGill University, Montreal Children's Hospital Research Institute, 4060 Ste. Catherine West, Suite 241, Montréal, Quebec, Canada H3Z 2Z3.

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http://dx.doi.org/10.1093/cvr/cvn157DOI Listing
October 2008

Fhua and HgbA, outer membrane proteins of Actinobacillus pleuropneumoniae: their role as virulence determinants.

Can J Microbiol 2006 Apr;52(4):391-6

Canadian Resrarch Network on Bacterial Pathogens of Swine, Université de Montréal, Canada.

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http://dx.doi.org/10.1139/w05-135DOI Listing
April 2006

Elevated homocysteine reduces apolipoprotein A-I expression in hyperhomocysteinemic mice and in males with coronary artery disease.

Circ Res 2006 Mar 26;98(4):564-71. Epub 2006 Jan 26.

Department of Human Genetics, Montreal Children's Hospital, Montreal, Canada.

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http://dx.doi.org/10.1161/01.RES.0000204825.66410.0bDOI Listing
March 2006

Molecular cloning of haemoglobin-binding protein HgbA in the outer membrane of Actinobacillus pleuropneumoniae.

Microbiology (Reading) 2004 Jun;150(Pt 6):1723-1734

Department of Microbiology and Immunology, McGill University, 3775 University Street, Montreal, QC, Canada H3A 2B4.

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http://dx.doi.org/10.1099/mic.0.27046-0DOI Listing
June 2004

fhuA of Actinobacillus pleuropneumoniae encodes a ferrichrome receptor but is not regulated by iron.

Infect Immun 2003 May;71(5):2911-5

Groupe de Recherche sur les Maladies Infectieuses du Porc, Département de pathologie et microbiologie, Faculté de médecine vétérinaire, Université de Montréal, Saint-Hyacinthe, Québec, Canada J2S 7C6.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC153255PMC
http://dx.doi.org/10.1128/iai.71.5.2911-2915.2003DOI Listing
May 2003

Molecular cloning and characterization of the ferric hydroxamate uptake (fhu) operon in Actinobacillus pleuropneumoniae.

Microbiology (Reading) 2002 Sep;148(Pt 9):2869-2882

Groupe de Recherche sur les Maladies Infectieuses du Porc, Département de Pathologie et Microbiologie, Faculté de Médecine Vétérinaire, Université de Montréal, Saint-Hyacinthe, Québec, CanadaJ2S 7C61.

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http://mic.microbiologyresearch.org/content/journal/micro/10
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http://dx.doi.org/10.1099/00221287-148-9-2869DOI Listing
September 2002