Leonie A Cluse

Leonie A Cluse

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Leonie A Cluse

Leonie A Cluse

Publications by authors named "Leonie A Cluse"

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14Publications

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A Comprehensive Protocol Resource for Performing Pooled shRNA and CRISPR Screens.

Methods Mol Biol 2018 ;1725:201-227

Victorian Centre for Functional Genomics, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.

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http://dx.doi.org/10.1007/978-1-4939-7568-6_17DOI Listing
January 2019

BET Inhibition Induces Apoptosis in Aggressive B-Cell Lymphoma via Epigenetic Regulation of BCL-2 Family Members.

Mol Cancer Ther 2016 09 12;15(9):2030-41. Epub 2016 Jul 12.

Gene Regulation Laboratory, Research Division, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia. Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, Victoria, Australia.

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http://dx.doi.org/10.1158/1535-7163.MCT-15-0924DOI Listing
September 2016

Functional-genetic dissection of HDAC dependencies in mouse lymphoid and myeloid malignancies.

Blood 2015 Nov 7;126(21):2392-403. Epub 2015 Oct 7.

Cancer Therapeutics Program, Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia; Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Victoria, Australia;

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http://dx.doi.org/10.1182/blood-2015-03-632984DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4653767PMC
November 2015

An intact immune system is required for the anticancer activities of histone deacetylase inhibitors.

Cancer Res 2013 Dec 24;73(24):7265-76. Epub 2013 Oct 24.

Authors' Affiliations: Cancer Therapeutics Program, and Cancer Immunology Program, Peter MacCallum Cancer Centre, East Melbourne; Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Victoria; The University of Queensland Diamantina Institute, Translational Research Institute, Woolloongabba; Queensland Institute of Medical Research; and School of Medicine, University of Queensland, Herston, Queensland, Australia.

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http://dx.doi.org/10.1158/0008-5472.CAN-13-0890DOI Listing
December 2013

Deciphering the molecular events necessary for synergistic tumor cell apoptosis mediated by the histone deacetylase inhibitor vorinostat and the BH3 mimetic ABT-737.

Cancer Res 2011 May 11;71(10):3603-15. Epub 2011 Mar 11.

Gene Regulation Laboratory, Cancer Therapeutics Program, The Peter MacCallum Cancer Institute, East Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1158/0008-5472.CAN-10-3289DOI Listing
May 2011

Defining the target specificity of ABT-737 and synergistic antitumor activities in combination with histone deacetylase inhibitors.

Blood 2009 Feb 5;113(9):1982-91. Epub 2008 Dec 5.

Cancer Immunology Program, The Peter MacCallum Cancer Centre, Trescowthick Research Laboratories, East Melbourne, Australia.

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http://dx.doi.org/10.1182/blood-2008-05-156851DOI Listing
February 2009

Characterisation of the novel apoptotic and therapeutic activities of the histone deacetylase inhibitor romidepsin.

Mol Cancer Ther 2008 May;7(5):1066-79

Cancer Immunology Program, Peter MacCallum Cancer Centre, Trescowthick Research Laboratories, St. Andrews Place, East Melbourne, Victoria 3002, Australia.

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http://dx.doi.org/10.1158/1535-7163.MCT-07-2256DOI Listing
May 2008

SOCS3 is a critical physiological negative regulator of G-CSF signaling and emergency granulopoiesis.

Immunity 2004 Feb;20(2):153-65

Cancer and Haematology Division, The Walter and Eliza Hall Institute of Medical Research and The Cooperative Research Centre for Cellular Growth Factors, Parkville, Victoria 3050, Australia.

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http://dx.doi.org/10.1016/s1074-7613(04)00022-6DOI Listing
February 2004

Rac2-deficient mice display perturbed T-cell distribution and chemotaxis, but only minor abnormalities in T(H)1 responses.

Immunol Cell Biol 2002 Jun;80(3):231-40

Divisions of Cancer, Walter and Eliza Hall Institute of Medical Research, Royal Melbourne Hospital, Parkville, Victoria, South Australia.

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http://dx.doi.org/10.1046/j.1440-1711.2002.01077.xDOI Listing
June 2002

The Rac2 guanosine triphosphatase regulates B lymphocyte antigen receptor responses and chemotaxis and is required for establishment of B-1a and marginal zone B lymphocytes.

J Immunol 2002 Apr;168(7):3376-86

Division of Cancer and Hematology and Immunology, Walter and Eliza Hall Institute of Medical Research, Royal Melbourne Hospital, Parkville, Victoria, Australia.

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http://dx.doi.org/10.4049/jimmunol.168.7.3376DOI Listing
April 2002