Publications by authors named "Leonel Fierro-Arias"

14 Publications

  • Page 1 of 1

Clinical and mycological study of 42 cases of dermatophytic granuloma (Majocchi granuloma).

J Dtsch Dermatol Ges 2021 05 22;19(5):758-761. Epub 2021 Apr 22.

Microbiology Department, Medicine Faculty, Universidad Autónoma de Nuevo León, Mexico.

View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.1111/ddg.14453DOI Listing
May 2021

Thoracic actinomycetoma: a retrospective clinical-epidemiological study of 64 cases.

Trans R Soc Trop Med Hyg 2021 04;115(4):337-339

Clinical Microbiology Laboratory, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Av. Vasco de Quiroga 15, Belisario Domínguez Sección XVI, Tlalpan, 14080 México City, México.

Background: Actinomycetoma is a chronic granulomatous infection that follows traumatic implantation. Thoracic actinomycetoma (TA) is rare and may lead to severe complications.

Methods: A retrospective study of cases of TA diagnosed from 1985 to 2019 was carried out. Each case underwent direct examination, culture and biopsy.

Results: Sixty-four cases (12.8%) were included, with a male predominance (84.3%); the main occupation was peasant farmer (71.8%) and the main site was the back (76.5%). Vertebral involvement was observed in 21.8% and pulmonary involvement in 7.8%. Nocardia brasiliensis was the main aetiological agent (53 cases, 74.5%).

Conclusions: TA is a poorly studied disease that can cause neurological and lung complications.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.1093/trstmh/trab037DOI Listing
April 2021

Actinomycetoma by . Clinical and therapeutic characteristics of 18 cases with two treatment modalities.

J Dermatolog Treat 2020 Jul 20:1-5. Epub 2020 Jul 20.

Microbiology Department, Facultad de Medicina y Hospital Universitario Dr. José Eleuterio González, Universidad Autónoma de Nuevo León, Monterrey, Mexico.

Background: Actinomycetoma due to is susceptible to numerous chemotherapeutic agents, however, the response to those treatments is variable and closely related to several factors.

Objective: We aimed to evaluate the clinical-therapeutic characteristics of patients with actinomycetoma due to with two treatment modalities.

Methods: This was a retrospective study of eighteen patients with a diagnosis of actinomycetoma. The most widely used therapeutic scheme was streptomycin 1 g every third day plus TMP/SMX 800 mg/160 mg/12h, followed by TMP/SMX with DDS 100 mg/day. In six patients (33%), ciprofloxacin 500 mg every 12 h was used instead of DDS.

Results: Conventional scheme achieved clinical and mycological cure in 58% of the cases, improvement in 16%, and 25% of the patients failed to treatment; in the cases treated with ciprofloxacin, clinical and microbiological cure was achieved in 83% of patients and clinical improvement in 16%. The treatment time to achieve clinical and mycological did not have a statistically significant difference (median 10 ± 1.38 vs. 12 ± 4.6).

Conclusion: Treatment based on streptomycin + TMP/SMX with ciprofloxacin was found to be effective in treating patients with actinomycetoma, and comparable to the conventional treatment with DDS in actinomycetoma due to with minimal bone involvement.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.1080/09546634.2020.1793887DOI Listing
July 2020

Treatment of Majocchi granuloma. A retrospective study of 36 cases.

J Dermatolog Treat 2021 03 12;32(2):264-265. Epub 2019 Aug 12.

Dermatology Service, Mycology Department, Hospital General de México, "Dr. Eduardo Liceaga", Mexico, Mexico.

View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.1080/09546634.2019.1646392DOI Listing
March 2021

Second joint position paper: Use of isotretinoin in severe acne

Rev Med Inst Mex Seguro Soc 2019 Jan 28;56(5):441-446. Epub 2019 Jan 28.

SPRIM Américas México, Gerencia de Investigación Clínica. Ciudad de México, México

Background: The use of isotretinoin is indicated in the treatment of severe acne; however, its adverse effects are important.

Objective: To update the first Mexican Consensus on the use of isotretinoin in severe acne vulgaris, which took place in 2009.

Methods: It was carried out a literature search between June 2009, and February 2015, in order to evaluate topics to be discussed; materials were sent to the experts to promote the debate among participants. The topics of interest were analyzed during the consensus with the Delphi modified method, using an instrument previously validated. 15 certified dermatologists with experience in handling acne with isotretinoin took part in the study; seven of them were involved in the previous consensus.

Results: Several cases of isolated adverse events were identified. Neither systematic reviews, meta-analyses nor comparative, randomized, controlled clinical trials were published during the observation period.

Conclusions: Isotretinoin is still the best treatment for severe nodulocystic acne. However, it must be taken into consideration its teratogenic effect on pregnant women and its association with inflammatory bowel disease, depression and suicidal ideas. Monitoring with laboratory tests is a tool for identifying possible adverse events.
View Article and Find Full Text PDF

Download full-text PDF

Source
January 2019

Dermatologists happiness and satisfaction

Gac Med Mex 2018 ;154(1):26-35

Servicio de Micología, Hospital General Dr. Manuel Gea González. Ciudad de México, México.

Objective: To assess the level of happiness and satisfaction in the life and medical practice of dermatologists in Mexico.

Method: A descriptive study (online survey) was conducted focused on practicing dermatologists in our country. Questions included demographic characteristics, the Pemberton happiness index (with local validation) and questions that assessed the degree of personal satisfaction. Descriptive statistics were used to obtain the central tendency and dispersion. Measures of central tendency and dispersion were performed; to compare categorical variables, contingency tables for chi-square test were used and when comparing quantitative variables with normal distribution, Student’s t t-test was used.

Results: 219 surveys were included, 72.6% female and 27.4% male, with an average age of 45.6 and an average of 16 years of medical practice. Most of them (64.8%) graduate from Mexico City; 93% were very satisfied with the specialty and 98.6% of them would choose the same once again, the most important reason is to encompass medical and surgical areas. The level of happiness by using the Pemberton scale was “high” (mode: 9.11; standard deviation: 1.73).

Conclusions: This first study in Latin America on this subject in dermatologists showed high levels of satisfaction and happiness in both professional and personal areas.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.24875/GMM.17002763DOI Listing
June 2018

Congenital Malalignment of the Great Toenail.

Skinmed 2015;13(6):433-7. Epub 2015 Dec 1.

Department of Dermatology, Mexico.

Congenital malalignment of the great toenail (CMA) is a disorder of the anatomic orientation of the ungual apparatus, in which the longitudinal axis of the nail plate is not parallel with the axis of the distal phalanx but is deflected sideways. This disorder is understood to arise from multiple factors. Although many theories have been proposed about its origin, its pathogenesis is not fully known. Besides the cosmetic impact, this disorder causes such problems in the medium and long term as onychocryptosis and difficulty in motion. Some cases may regress spontaneously, although persistent cases may require a specialized surgical approach. Congenital malalignment of the great toenail is poorly understood and described medical condition that is often treated incorrectly; thus, reviewing the subject is important. A symptombased clinical classification system is proposed to guide diagnosis and treatment modality decisions.
View Article and Find Full Text PDF

Download full-text PDF

Source
December 2015

[Nail changes associated with distal renal tubular acidosis in pediatric patients].

Gac Med Mex 2015 Sep-Oct;151(5):614-9

Residente de segundo año de dermatología. Centro Dermatológico «Dr. Ladislao de la Pascua», México, D.F., México.

Renal tubular acidosis is a disease prevalent in childhood, responsible for a decrease in growth due inadequate acid-base levels regulation. It is well known that systemic conditions can generate or accompany nail changes by different pathophysiologic mechanisms, however no one has ever found or reported any association of onychopathy with renal tubular acidosis so far. That is why we would like to share our experience on this topic.
View Article and Find Full Text PDF

Download full-text PDF

Source
March 2016

Periungual eccrine poroma.

J Cutan Med Surg 2015 Jan-Feb;19(1):84-6. Epub 2015 Jan 1.

Dermatologic Surgery and Oncology Unit, Dermatology Service, and Dermatopathology Service, Hospital General de México, Mexico City, Mexico.

Background: Eccrine poroma is a rare, benign skin appendage tumor originating from the intraepidermal portion of the eccrine sweat duct, which typically occurs on the sides and soles of the feet. Nonetheless, eccrine poroma may be found in any skin area bearing sweat glands.

Objective: Herein we report a case of an eccrine poroma in an unusual location, the surgical management of the condition, and follow-up processes.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.2310/7750.2014.14012DOI Listing
September 2015

Periungual eccrine poroma.

J Cutan Med Surg 2014 Oct;18(5):1-3

Background: Eccrine poroma is a rare, benign skin appendage tumor originating from the intraepidermal portion of the eccrine sweat duct, which typically occurs on the sides and soles of the feet. Nonetheless, eccrine poroma may be found in any skin area bearing sweat glands.

Objective: Herein we report a case of an eccrine poroma in an unusual location, the surgical management of the condition, and follow-up processes.
View Article and Find Full Text PDF

Download full-text PDF

Source
October 2014

[Position paper about isotretinoin on acne vulgaris].

Rev Med Inst Mex Seguro Soc 2011 May-Jun;49(3):281-8

Servicio de Dermatología, Hospital Universitario José Eleuterio González, Monterrey, Nuevo León, México.

Isotretinoin was authorized since 1982 for the treatment of acne vulgaris associated to severe cutaneous lesions. It has been used in others clinical conditions in various plans of prescription. Since the Isotretinoin was launched, it caused controversies in our country and around the world, especially in relation with the security. Isotretinoin is proscribed in pregnant patient. As a security rule we must measure serum lipids and hepatic enzymes. The aim of the consensus was to spread information worked by a group of Mexican experienced dermatologists to the health professionals about the use and the specific indications about isotretinoin.
View Article and Find Full Text PDF

Download full-text PDF

Source
September 2011

[Skin cancer in adults younger than 40 years at the General Hospital of Mexico].

Gac Med Mex 2011 Jan-Feb;147(1):17-21

Departamento de Dermatología, Hospital General de México, México, D.F.

Skin cancer is the most common malignant neoplasm reported worldwide. Over the last 20 years, skin cancer has been recognized in a high proportion among young people not associated with genetic disorders or other diseases. In Mexico there is no epidemiological information about this topic, so we made a retrospective study from 2006 to 2009 in the Dermatology service of the General Hospital of Mexico. We included 730 patients with diagnosis of primary skin cancer; 51 cases occurred in people younger than 40 years with an average age of 38 years, and with an estimated accumulated incidence of 6.8% for the elapsed time. In this study, skin cancer in young people showed a predominance of women (67% of patients); basal cell carcinoma was the most common type. Most of the lesions were found in sun-exposed areas. Skin cancer in people younger than 40 years is increasing dramatically, so we recommend avoiding ultraviolet radiation exposure in childhood and adolescence, and implementing sun-protection campaigns in order to educate this sector of the population and make them more aware of the potential dangers.
View Article and Find Full Text PDF

Download full-text PDF

Source
June 2011

Mycetoma in children: experience with 15 cases.

Pediatr Infect Dis J 2007 Jan;26(1):50-2

Mycology Department, Hospital General de Mexico, Mexico City, Mexico.

Background: Mycetoma is a chronic infection caused by aerobic actinomycetes and filamentous fungi. It is an occupational disease frequent in tropical countries and is uncommon in children.

Methods: A retrospective (25 years) report of mycetomas was conducted in children less than 15 years of age. Each of the cases was studied clinically and proven with microbiologic tests: direct examinations (to identify and classify the grains), cultures and identification based on morphology and biochemical tests. The therapeutic experience of the cases was also reviewed.

Results: In a 25-year period, a total of 334 mycetomas were seen at our institution, 15 of which (4.5%) were in patients 15 years of age and younger (mean age: 11.2 years, age range: 6-15 years). Twelve cases were males and 3 females. The main clinical location was the foot in 10 of 15 (66.6%). Etiologies included 13 actinomycetomas and 2 eumycetomas. Etiologic agents were Nocardia brasiliensis in 12 cases, Nocardia asteroides in one and Madurella mycetomatis in 2. Eleven of the13 cases of actinomycetomas treated with trimethoprim-sulfamethoxazole plus diaminodiphenylsulfone were cured. The 2 failures were successfully treated with amoxicillin/clavulanate. One of the eumycetomas was cured with itraconazole therapy, whereas the other failed various treatments eventuating in surgical amputation.

Conclusions: Mycetomas are exceptional in children; in our setting, actinomycetomas are more frequent than eumycetomas. The clinical and microbiologic diagnosis is simple. Overall, treatment response is better for actinomycetomas than for eumycetomas.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.1097/01.inf.0000247108.86199.64DOI Listing
January 2007
-->