Publications by authors named "Leonard van den Berg"

100Publications

Excitability of motor and sensory axons in multifocal motor neuropathy.

Clin Neurophysiol 2020 Aug 26;131(11):2641-2650. Epub 2020 Aug 26.

Department of Neurology, Brain Center Utrecht, University Medical Center Utrecht, Utrecht, the Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.clinph.2020.08.004DOI Listing
August 2020

Dutch population structure across space, time and GWAS design.

Nat Commun 2020 09 11;11(1):4556. Epub 2020 Sep 11.

Smurfit Institute of Genetics, Trinity College Dublin, Dublin, D02 DK07, Republic of Ireland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41467-020-18418-4DOI Listing
September 2020

Current trends in the clinical trial landscape for amyotrophic lateral sclerosis.

Curr Opin Neurol 2020 Oct;33(5):655-661

Department of Neurology, UMC Utrecht Brain Centre.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/WCO.0000000000000861DOI Listing
October 2020

Is it accurate to classify ALS as a neuromuscular disorder?

Expert Rev Neurother 2020 Sep 1:1-12. Epub 2020 Sep 1.

Department of Neurology, UMC Utrecht Brain Center, University Medical Center Utrecht , Utrecht, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/14737175.2020.1806061DOI Listing
September 2020

Muscle strength and motor function in adolescents and adults with spinal muscular atrophy.

Neurology 2020 Jul 30. Epub 2020 Jul 30.

C. A. Wijngaarde, M. Stam, L.A.M. Otto, F. Asselman, R.P.A. van Eijk, L.H. van den Berg, H.S. Goedee, R.I. Wadman, and W.L. van der Pol: Department of Neurology, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, The Netherlands

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1212/WNL.0000000000010540DOI Listing
July 2020

Clinical outcomes in multifocal motor neuropathy: A combined cross-sectional and follow-up study.

Neurology 2020 Jul 30. Epub 2020 Jul 30.

UMC Utrecht Brain Center Rudolf Magnus, Department of Neurology and Neurosurgery, Heidelberglaan 100, 3584 CX, The Netherlands

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1212/WNL.0000000000010538DOI Listing
July 2020

Nerve ultrasound for diagnosing chronic inflammatory neuropathy: a multicenter validation study.

Neurology 2020 Jul 16. Epub 2020 Jul 16.

UMC Utrecht Brain Center Rudolf Magnus, Department of Neurology and Neurosurgery, Heidelberglaan 100, 3584 CX, The Netherlands

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1212/WNL.0000000000010369DOI Listing
July 2020

TRICALS: creating a highway toward a cure.

Amyotroph Lateral Scler Frontotemporal Degener 2020 Jul 9:1-6. Epub 2020 Jul 9.

Department of Neurology, UMC Utrecht Brain Centre, University Medical Centre Utrecht, Utrecht, the Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/21678421.2020.1788092DOI Listing
July 2020

The Beginning of Genomic Therapies for ALS.

N Engl J Med 2020 07;383(2):180-181

From Trinity College and Beaumont Hospital, Dublin (O.H.); and University Medical Center, Utrecht, the Netherlands (L.H.B.).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1056/NEJMe2012930DOI Listing
July 2020

A placebo-controlled trial to investigate the safety and efficacy of Penicillin G/Hydrocortisone in patients with ALS (PHALS trial).

Amyotroph Lateral Scler Frontotemporal Degener 2020 Jul 6:1-9. Epub 2020 Jul 6.

Department of Neurology, UMC Utrecht Brain Center, University Medical Centre Utrecht, Utrecht, the Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/21678421.2020.1788093DOI Listing
July 2020

The Distinct Traits of the UNC13A Polymorphism in Amyotrophic Lateral Sclerosis.

Ann Neurol 2020 Jul 6. Epub 2020 Jul 6.

Department of Neurology, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/ana.25841DOI Listing
July 2020

Using patient-reported symptoms of dyspnea for screening reduced respiratory function in patients with motor neuron diseases.

J Neurol 2020 Jun 23. Epub 2020 Jun 23.

Department of Rehabilitation, Physical Therapy Science and Sports, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX, Utrecht, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00415-020-10003-5DOI Listing
June 2020

Prognostic value of weight loss in patients with amyotrophic lateral sclerosis: a population-based study.

J Neurol Neurosurg Psychiatry 2020 Aug 23;91(8):867-875. Epub 2020 Jun 23.

Neurology, University Medical Centre Utrecht Brain Centre, Utrecht, The Netherlands

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/jnnp-2020-322909DOI Listing
August 2020

Transethnic Genome-Wide Association Study Provides Insights in the Genetic Architecture and Heritability of Long QT Syndrome.

Authors:
Najim Lahrouchi Rafik Tadros Lia Crotti Yuka Mizusawa Pieter G Postema Leander Beekman Roddy Walsh Kanae Hasegawa Julien Barc Marko Ernsting Kari L Turkowski Andrea Mazzanti Britt M Beckmann Keiko Shimamoto Ulla-Britt Diamant Yanushi D Wijeyeratne Yu Kucho Tomas Robyns Taisuke Ishikawa Elena Arbelo Michael Christiansen Annika Winbo Reza Jabbari Steven A Lubitz Johannes Steinfurt Boris Rudic Bart Loeys M Ben Shoemaker Peter E Weeke Ryan Pfeiffer Brianna Davies Antoine Andorin Nynke Hofman Federica Dagradi Matteo Pedrazzini David J Tester J Martijn Bos Georgia Sarquella-Brugada Óscar Campuzano Pyotr G Platonov Birgit Stallmeyer Sven Zumhagen Eline A Nannenberg Jan H Veldink Leonard H van den Berg Ammar Al-Chalabi Christopher E Shaw Pamela J Shaw Karen E Morrison Peter M Andersen Martina Müller-Nurasyid Daniele Cusi Cristina Barlassina Pilar Galan Mark Lathrop Markus Munter Thomas Werge Marta Ribasés Tin Aung Chiea C Khor Mineo Ozaki Peter Lichtner Thomas Meitinger J Peter van Tintelen Yvonne Hoedemaekers Isabelle Denjoy Antoine Leenhardt Carlo Napolitano Wataru Shimizu Jean-Jacques Schott Jean-Baptiste Gourraud Takeru Makiyama Seiko Ohno Hideki Itoh Andrew D Krahn Charles Antzelevitch Dan M Roden Johan Saenen Martin Borggrefe Katja E Odening Patrick T Ellinor Jacob Tfelt-Hansen Jonathan R Skinner Maarten P van den Berg Morten Salling Olesen Josep Brugada Ramón Brugada Naomasa Makita Jeroen Breckpot Masao Yoshinaga Elijah R Behr Annika Rydberg Takeshi Aiba Stefan Kääb Silvia G Priori Pascale Guicheney Hanno L Tan Christopher Newton-Cheh Michael J Ackerman Peter J Schwartz Eric Schulze-Bahr Vincent Probst Minoru Horie Arthur A Wilde Michael W T Tanck Connie R Bezzina

Circulation 2020 Jul 20;142(4):324-338. Epub 2020 May 20.

Amsterdam UMC, University of Amsterdam, Heart Center; Department of Clinical and Experimental Cardiology, Amsterdam Cardiovascular Sciences, The Netherlands (N.L., R.T., Y.M., P.G.P., L.B., R.W., N.H., H.L.T., A.A.W., C.R.B.).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/CIRCULATIONAHA.120.045956DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7382531PMC
July 2020

Multimodal longitudinal study of structural brain involvement in amyotrophic lateral sclerosis.

Neurology 2020 06 15;94(24):e2592-e2604. Epub 2020 May 15.

From the Department of Neurology (H.K.v.d.B., H.-J.W., R.W., K.v.V., H.H.G.T., J.M.M., L.A.B., M.A.v.E., J.H.V., L.H.v.d.B.), Center of Excellence for Rehabilitation Medicine (L.A.B.), and Department of Radiology (J.H.), UMC Utrecht Brain Center, University Medical Center Utrecht; De Hoogstraat Rehabilitation (L.A.B.), Utrecht; and Department of Complex Trait Genetics (M.P.v.d.H.), Center for Neurogenomics and Cognitive Research, VU University Amsterdam, the Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1212/WNL.0000000000009498DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7455328PMC
June 2020

Blended psychosocial support for partners of patients with ALS and PMA: results of a randomized controlled trial.

Amyotroph Lateral Scler Frontotemporal Degener 2020 Aug 2;21(5-6):344-354. Epub 2020 May 2.

Center of Excellence for Rehabilitation Medicine, UMC Utrecht Brain Center, University Medical Center Utrecht, and De Hoogstraat Rehabilitation, Utrecht, the Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/21678421.2020.1757114DOI Listing
August 2020

Assessment of motor unit loss in patients with spinal muscular atrophy.

Clin Neurophysiol 2020 Jun 13;131(6):1280-1286. Epub 2020 Feb 13.

Department of Neurology, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, the Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.clinph.2020.01.018DOI Listing
June 2020

Natural history of lung function in spinal muscular atrophy.

Orphanet J Rare Dis 2020 04 10;15(1):88. Epub 2020 Apr 10.

Department of Neurology, UMC Utrecht Brain Centre, University Medical Centre Utrecht, Utrecht University, Heidelberglaan 100, 3508, GA, Utrecht, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13023-020-01367-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7149916PMC
April 2020

Population-based analysis of survival in spinal muscular atrophy.

Neurology 2020 04 26;94(15):e1634-e1644. Epub 2020 Mar 26.

From the Department of Neurology, UMC Utrecht Brain Center (C.A.W., M.S., L.A.M.O., R.P.A.v.E., I.C., L.H.v.d.B., R.I.W., W.L.v.d.P.), Biostatistics & Research Support, Julius Center for Health Sciences and Primary Care (R.P.A.v.E.), and Department of Pediatric Intensive Care (E.S.V.), University Medical Center Utrecht, Utrecht University, the Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1212/WNL.0000000000009248DOI Listing
April 2020

Connectome-Based Propagation Model in Amyotrophic Lateral Sclerosis.

Ann Neurol 2020 05 11;87(5):725-738. Epub 2020 Mar 11.

Dutch Connectome Lab, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Free University Amsterdam, Amsterdam, the Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/ana.25706DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7186838PMC
May 2020

Analysis of , , and as potential disease severity modifiers in spinal muscular atrophy.

Neurol Genet 2020 Feb 3;6(1):e386. Epub 2019 Jan 3.

Department of Neurology (R.I.W., M.D.J., C.A.D.C., E.J.N.G., M.S., C.A.W., J.M., P.S., K.R.E., W.R., J.H.V., L.H.B., W.L.P.), Brain Center Rudolf Magnus, University Medical Center Utrecht; Department of Pathology (M.M.H.H., J.K.), University Medical Center Utrecht; Department of Genetics (M.M.H.H.), University Medical Center Utrecht; and Department of Genetics (H.H.L.), University Medical Center Groningen, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1212/NXG.0000000000000386DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6975178PMC
February 2020

Primary lateral sclerosis: consensus diagnostic criteria.

J Neurol Neurosurg Psychiatry 2020 04 6;91(4):373-377. Epub 2020 Feb 6.

Neurology, Columbia University College of Physicians and Surgeons, New York City, New York, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/jnnp-2019-322541DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7147236PMC
April 2020

Drug treatment for spinal muscular atrophy types II and III.

Cochrane Database Syst Rev 2020 01 6;1:CD006282. Epub 2020 Jan 6.

University Medical Center Utrecht, Brain Center Rudolf Magnus, Department of Neurology, Heidelberglaan 100, Utrecht, Netherlands, 3584 CX.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/14651858.CD006282.pub5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6995983PMC
January 2020

Telehealth as part of specialized ALS care: feasibility and user experiences with "ALS home-monitoring and coaching".

Amyotroph Lateral Scler Frontotemporal Degener 2020 05 31;21(3-4):183-192. Epub 2020 Jan 31.

Department of Rehabilitation, Physical Therapy Science and Sports, UMC Utrecht Brain Centre, University Medical Centre, Utrecht, the Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/21678421.2020.1718712DOI Listing
May 2020

Nerve ultrasound improves detection of treatment-responsive chronic inflammatory neuropathies.

Neurology 2020 04 20;94(14):e1470-e1479. Epub 2020 Jan 20.

From the Department of Neurology and Neurosurgery (I.J.T.H., H.S.G., J.A.T., R.P.A.v.E., L.H.v.d.B., W.L.v.d.P.), UMC Utrecht Brain Center Rudolf Magnus; Department of Neurology and Clinical Neurophysiology (I.J.T.H., J.A.T., J.T.v.A., L.H.V.), Elisabeth-Tweesteden Hospital Tilburg; and Biostatistics & Research Support (R.P.A.v.E.), Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, the Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1212/WNL.0000000000008978DOI Listing
April 2020

The current use of telehealth in ALS care and the barriers to and facilitators of implementation: a systematic review.

Amyotroph Lateral Scler Frontotemporal Degener 2020 05 26;21(3-4):167-182. Epub 2019 Dec 26.

Department of Rehabilitation, Physical Therapy Science & Sports, UMC Utrecht Brain Centre, University Medical Centre Utrecht, the Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/21678421.2019.1706581DOI Listing
May 2020

Drug treatment for spinal muscular atrophy type I.

Cochrane Database Syst Rev 2019 12 11;12:CD006281. Epub 2019 Dec 11.

University Medical Center Utrecht, Brain Center Rudolf Magnus, Department of Neurology, Heidelberglaan 100, Utrecht, Netherlands, 3584 CX.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/14651858.CD006281.pub5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6905354PMC
December 2019

Psychological distress in partners of patients with amyotrophic lateral sclerosis and progressive muscular atrophy: what's the role of care demands and perceived control?

Psychol Health Med 2020 03 20;25(3):319-330. Epub 2019 Nov 20.

Center of Excellence in Rehabilitation Medicine, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht University and De Hoogstraat Rehabilitation, Utrecht, the Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/13548506.2019.1686646DOI Listing
March 2020

Associations of autozygosity with a broad range of human phenotypes.

Authors:
David W Clark Yukinori Okada Kristjan H S Moore Dan Mason Nicola Pirastu Ilaria Gandin Hannele Mattsson Catriona L K Barnes Kuang Lin Jing Hua Zhao Patrick Deelen Rebecca Rohde Claudia Schurmann Xiuqing Guo Franco Giulianini Weihua Zhang Carolina Medina-Gomez Robert Karlsson Yanchun Bao Traci M Bartz Clemens Baumbach Ginevra Biino Matthew J Bixley Marco Brumat Jin-Fang Chai Tanguy Corre Diana L Cousminer Annelot M Dekker David A Eccles Kristel R van Eijk Christian Fuchsberger He Gao Marine Germain Scott D Gordon Hugoline G de Haan Sarah E Harris Edith Hofer Alicia Huerta-Chagoya Catherine Igartua Iris E Jansen Yucheng Jia Tim Kacprowski Torgny Karlsson Marcus E Kleber Shengchao Alfred Li Ruifang Li-Gao Anubha Mahajan Koichi Matsuda Karina Meidtner Weihua Meng May E Montasser Peter J van der Most Matthias Munz Teresa Nutile Teemu Palviainen Gauri Prasad Rashmi B Prasad Tallapragada Divya Sri Priyanka Federica Rizzi Erika Salvi Bishwa R Sapkota Daniel Shriner Line Skotte Melissa C Smart Albert Vernon Smith Ashley van der Spek Cassandra N Spracklen Rona J Strawbridge Salman M Tajuddin Stella Trompet Constance Turman Niek Verweij Clara Viberti Lihua Wang Helen R Warren Robyn E Wootton Lisa R Yanek Jie Yao Noha A Yousri Wei Zhao Adebowale A Adeyemo Saima Afaq Carlos Alberto Aguilar-Salinas Masato Akiyama Matthew L Albert Matthew A Allison Maris Alver Tin Aung Fereidoun Azizi Amy R Bentley Heiner Boeing Eric Boerwinkle Judith B Borja Gert J de Borst Erwin P Bottinger Linda Broer Harry Campbell Stephen Chanock Miao-Li Chee Guanjie Chen Yii-Der I Chen Zhengming Chen Yen-Feng Chiu Massimiliano Cocca Francis S Collins Maria Pina Concas Janie Corley Giovanni Cugliari Rob M van Dam Anna Damulina Maryam S Daneshpour Felix R Day Graciela E Delgado Klodian Dhana Alexander S F Doney Marcus Dörr Ayo P Doumatey Nduna Dzimiri S Sunna Ebenesersdóttir Joshua Elliott Paul Elliott Ralf Ewert Janine F Felix Krista Fischer Barry I Freedman Giorgia Girotto Anuj Goel Martin Gögele Mark O Goodarzi Mariaelisa Graff Einat Granot-Hershkovitz Francine Grodstein Simonetta Guarrera Daniel F Gudbjartsson Kamran Guity Bjarni Gunnarsson Yu Guo Saskia P Hagenaars Christopher A Haiman Avner Halevy Tamara B Harris Mehdi Hedayati David A van Heel Makoto Hirata Imo Höfer Chao Agnes Hsiung Jinyan Huang Yi-Jen Hung M Arfan Ikram Anuradha Jagadeesan Pekka Jousilahti Yoichiro Kamatani Masahiro Kanai Nicola D Kerrison Thorsten Kessler Kay-Tee Khaw Chiea Chuen Khor Dominique P V de Kleijn Woon-Puay Koh Ivana Kolcic Peter Kraft Bernhard K Krämer Zoltán Kutalik Johanna Kuusisto Claudia Langenberg Lenore J Launer Deborah A Lawlor I-Te Lee Wen-Jane Lee Markus M Lerch Liming Li Jianjun Liu Marie Loh Stephanie J London Stephanie Loomis Yingchang Lu Jian'an Luan Reedik Mägi Ani W Manichaikul Paolo Manunta Gísli Másson Nana Matoba Xue W Mei Christa Meisinger Thomas Meitinger Massimo Mezzavilla Lili Milani Iona Y Millwood Yukihide Momozawa Amy Moore Pierre-Emmanuel Morange Hortensia Moreno-Macías Trevor A Mori Alanna C Morrison Taulant Muka Yoshinori Murakami Alison D Murray Renée de Mutsert Josyf C Mychaleckyj Mike A Nalls Matthias Nauck Matt J Neville Ilja M Nolte Ken K Ong Lorena Orozco Sandosh Padmanabhan Gunnar Pálsson James S Pankow Cristian Pattaro Alison Pattie Ozren Polasek Neil Poulter Peter P Pramstaller Lluis Quintana-Murci Katri Räikkönen Sarju Ralhan Dabeeru C Rao Wouter van Rheenen Stephen S Rich Paul M Ridker Cornelius A Rietveld Antonietta Robino Frank J A van Rooij Daniela Ruggiero Yasaman Saba Charumathi Sabanayagam Maria Sabater-Lleal Cinzia Felicita Sala Veikko Salomaa Kevin Sandow Helena Schmidt Laura J Scott William R Scott Bahareh Sedaghati-Khayat Bengt Sennblad Jessica van Setten Peter J Sever Wayne H-H Sheu Yuan Shi Smeeta Shrestha Sharvari Rahul Shukla Jon K Sigurdsson Timo Tonis Sikka Jai Rup Singh Blair H Smith Alena Stančáková Alice Stanton John M Starr Lilja Stefansdottir Leon Straker Patrick Sulem Gardar Sveinbjornsson Morris A Swertz Adele M Taylor Kent D Taylor Natalie Terzikhan Yih-Chung Tham Gudmar Thorleifsson Unnur Thorsteinsdottir Annika Tillander Russell P Tracy Teresa Tusié-Luna Ioanna Tzoulaki Simona Vaccargiu Jagadish Vangipurapu Jan H Veldink Veronique Vitart Uwe Völker Eero Vuoksimaa Salma M Wakil Melanie Waldenberger Gurpreet S Wander Ya Xing Wang Nicholas J Wareham Sarah Wild Chittaranjan S Yajnik Jian-Min Yuan Lingyao Zeng Liang Zhang Jie Zhou Najaf Amin Folkert W Asselbergs Stephan J L Bakker Diane M Becker Benjamin Lehne David A Bennett Leonard H van den Berg Sonja I Berndt Dwaipayan Bharadwaj Lawrence F Bielak Murielle Bochud Mike Boehnke Claude Bouchard Jonathan P Bradfield Jennifer A Brody Archie Campbell Shai Carmi Mark J Caulfield David Cesarini John C Chambers Giriraj Ratan Chandak Ching-Yu Cheng Marina Ciullo Marilyn Cornelis Daniele Cusi George Davey Smith Ian J Deary Rajkumar Dorajoo Cornelia M van Duijn David Ellinghaus Jeanette Erdmann Johan G Eriksson Evangelos Evangelou Michele K Evans Jessica D Faul Bjarke Feenstra Mary Feitosa Sylvain Foisy Andre Franke Yechiel Friedlander Paolo Gasparini Christian Gieger Clicerio Gonzalez Philippe Goyette Struan F A Grant Lyn R Griffiths Leif Groop Vilmundur Gudnason Ulf Gyllensten Hakon Hakonarson Anders Hamsten Pim van der Harst Chew-Kiat Heng Andrew A Hicks Hagit Hochner Heikki Huikuri Steven C Hunt Vincent W V Jaddoe Philip L De Jager Magnus Johannesson Åsa Johansson Jost B Jonas J Wouter Jukema Juhani Junttila Jaakko Kaprio Sharon L R Kardia Fredrik Karpe Meena Kumari Markku Laakso Sander W van der Laan Jari Lahti Matthias Laudes Rodney A Lea Wolfgang Lieb Thomas Lumley Nicholas G Martin Winfried März Giuseppe Matullo Mark I McCarthy Sarah E Medland Tony R Merriman Andres Metspalu Brian F Meyer Karen L Mohlke Grant W Montgomery Dennis Mook-Kanamori Patricia B Munroe Kari E North Dale R Nyholt Jeffery R O'connell Carole Ober Albertine J Oldehinkel Walter Palmas Colin Palmer Gerard G Pasterkamp Etienne Patin Craig E Pennell Louis Perusse Patricia A Peyser Mario Pirastu Tinca J C Polderman David J Porteous Danielle Posthuma Bruce M Psaty John D Rioux Fernando Rivadeneira Charles Rotimi Jerome I Rotter Igor Rudan Hester M Den Ruijter Dharambir K Sanghera Naveed Sattar Reinhold Schmidt Matthias B Schulze Heribert Schunkert Robert A Scott Alan R Shuldiner Xueling Sim Neil Small Jennifer A Smith Nona Sotoodehnia E-Shyong Tai Alexander Teumer Nicholas J Timpson Daniela Toniolo David-Alexandre Tregouet Tiinamaija Tuomi Peter Vollenweider Carol A Wang David R Weir John B Whitfield Cisca Wijmenga Tien-Yin Wong John Wright Jingyun Yang Lei Yu Babette S Zemel Alan B Zonderman Markus Perola Patrik K E Magnusson André G Uitterlinden Jaspal S Kooner Daniel I Chasman Ruth J F Loos Nora Franceschini Lude Franke Chris S Haley Caroline Hayward Robin G Walters John R B Perry Tōnu Esko Agnar Helgason Kari Stefansson Peter K Joshi Michiaki Kubo James F Wilson

Nat Commun 2019 10 31;10(1):4957. Epub 2019 Oct 31.

Centre for Global Health Research, Usher Institute, University of Edinburgh, Edinburgh, EH8 9AG, Scotland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41467-019-12283-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6823371PMC
October 2019

Pharmacogenetic interactions in amyotrophic lateral sclerosis: a step closer to a cure?

Pharmacogenomics J 2020 04 17;20(2):220-226. Epub 2019 Oct 17.

Department of Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41397-019-0111-3DOI Listing
April 2020

Magnetic resonance imaging of the cervical spinal cord in spinal muscular atrophy.

Neuroimage Clin 2019 3;24:102002. Epub 2019 Sep 3.

UMC Utrecht Brain Center, Department of Neurology, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.nicl.2019.102002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6812296PMC
September 2019

In pursuit of the normal progressor: the holy grail for ALS clinical trial design?

Amyotroph Lateral Scler Frontotemporal Degener 2020 02 11;21(1-2):1-2. Epub 2019 Oct 11.

Department of Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, the Netherlands and.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/21678421.2019.1675710DOI Listing
February 2020

Prospective natural history study of ALS clinical characteristics and biomarkers.

Neurology 2019 10 2;93(17):e1605-e1617. Epub 2019 Oct 2.

From the Department of Neurology (A.J.C., T.H., C.D., J.J.-B., A.M., S.B., A.S., T.J.E., C.C., T.M.M.), Washington University School of Medicine, St. Louis, MO; Department of Neurology (N.A., H.Y., A.V.S., M.C.), Neurological Clinical Research Institute, Massachusetts General Hospital, Boston; Department of Neurology (L.H.v.d.B., M.A.v.E., J.H.V., B.S.d.V.), Brain Center Rudolf Magnus, University Medical Center Utrecht, University Utrecht, the Netherlands; Department of Neurology (M.H.), Columbia University, New York, NY; Department of Neurology (R.H. Baloh), Cedars-Sinai Medical Center, Los Angeles, CA; Department of Neurology (R.H. Brown, N.W., D.M.-Y., M.A.O., C.D.), University of Massachusetts, Worcester; Department of Neurology (J.D.R.), Johns Hopkins University, Baltimore, MD; and Biogen Inc. (A.M., T.F.), Boston, MA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1212/WNL.0000000000008359DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6946465PMC
October 2019

Development and assessment of the inter-rater and intra-rater reproducibility of a self-administration version of the ALSFRS-R.

J Neurol Neurosurg Psychiatry 2020 01 26;91(1):75-81. Epub 2019 Sep 26.

Department of Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, The Netherlands

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/jnnp-2019-321138DOI Listing
January 2020

Multifocal motor neuropathy: controversies and priorities.

J Neurol Neurosurg Psychiatry 2020 02 11;91(2):140-148. Epub 2019 Sep 11.

Department of Neurology, Royal Hobart Hospital, Hobart, Tasmania, Australia

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/jnnp-2019-321532DOI Listing
February 2020

Cross-sectional and longitudinal assessment of the upper cervical spinal cord in motor neuron disease.

Neuroimage Clin 2019 16;24:101984. Epub 2019 Aug 16.

Department of Neurology, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht, The Netherlands. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.nicl.2019.101984DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6734179PMC
August 2019

Human immune globulin 10% with recombinant human hyaluronidase in multifocal motor neuropathy.

J Neurol 2019 Nov 19;266(11):2734-2742. Epub 2019 Jul 19.

Department of Neurology and Neurosurgery, UMC Utrecht Brain Center Rudolf Magnus, Heidelberglaan 100, 3584 CX, Utrecht, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00415-019-09475-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6803588PMC
November 2019

Nerve ultrasound can identify treatment-responsive chronic neuropathies without electrodiagnostic features of demyelination.

Muscle Nerve 2019 10 24;60(4):415-419. Epub 2019 Jul 24.

Brain Centre Rudolf Magnus, Department of Neurology and Neurosurgery, University Medical Center Utrecht, Utrecht, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/mus.26629DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6771613PMC
October 2019

Critical design considerations for time-to-event endpoints in amyotrophic lateral sclerosis clinical trials.

J Neurol Neurosurg Psychiatry 2019 12 10;90(12):1331-1337. Epub 2019 Jul 10.

Department of Neurology, Brain Center Rudolf Magnus, University Medical Centre Utrecht, Utrecht, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/jnnp-2019-320998DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6902062PMC
December 2019

Simulating perinodal changes observed in immune-mediated neuropathies: impact on conduction in a model of myelinated motor and sensory axons.

J Neurophysiol 2019 09 10;122(3):1036-1049. Epub 2019 Jul 10.

Department of Neurology, Brain Center Utrecht, University Medical Center Utrecht, Utrecht, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1152/jn.00326.2019DOI Listing
September 2019

Safety and tolerability of Triumeq in amyotrophic lateral sclerosis: the Lighthouse trial.

Amyotroph Lateral Scler Frontotemporal Degener 2019 11 8;20(7-8):595-604. Epub 2019 Jul 8.

King's College London, Maurice Wohl Clinical Neuroscience Institute, Department of Basic and Clinical Neuroscience , London , United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/21678421.2019.1632899DOI Listing
November 2019

A case of ALS with posterior cortical atrophy.

Amyotroph Lateral Scler Frontotemporal Degener 2019 11 8;20(7-8):506-510. Epub 2019 Jul 8.

Department of Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht University , Utrecht , The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/21678421.2019.1632348DOI Listing
November 2019

Amyotrophic lateral sclerosis as a multi-step process: an Australia population study.

Amyotroph Lateral Scler Frontotemporal Degener 2019 11 8;20(7-8):532-537. Epub 2019 Jul 8.

Brain and Mind Centre, University of Sydney and Institute of Clinical Neurosciences, Royal Prince Alfred Hospital , Sydney , Australia.

View Article

Download full-text PDF

Source
https://www.tandfonline.com/doi/full/10.1080/21678421.2018.1
Publisher Site
http://dx.doi.org/10.1080/21678421.2018.1556697DOI Listing
November 2019

The project MinE databrowser: bringing large-scale whole-genome sequencing in ALS to researchers and the public.

Amyotroph Lateral Scler Frontotemporal Degener 2019 08;20(5-6):432-440

a Department of Neurology , Brain Center Rudolf Magnus, University Medical Center Utrecht , Utrecht , The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/21678421.2019.1606244DOI Listing
August 2019

Implications of spirometric reference values for amyotrophic lateral sclerosis.

Amyotroph Lateral Scler Frontotemporal Degener 2019 11 4;20(7-8):473-480. Epub 2019 Jul 4.

Department of Neurology, Brain Centre Rudolf Magnus, University Medical Centre Utrecht , Utrecht , the Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/21678421.2019.1634736DOI Listing
November 2019

Neuropathy associated with immunoglobulin M monoclonal gammopathy: A combined sonographic and nerve conduction study.

Muscle Nerve 2019 09 24;60(3):263-270. Epub 2019 Jul 24.

Brain Center Rudolf Magnus, Department of Neurology and Neurosurgery, University Medical Center Utrecht, Utrecht, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/mus.26626DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6771847PMC
September 2019

Warming nerves for excitability testing.

Muscle Nerve 2019 09 10;60(3):279-285. Epub 2019 Jul 10.

Department of Neurology, University Medical Center Utrecht, Brain Center, Utrecht University, P.O. Box 85500, 3508 GA, Utrecht, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/mus.26621DOI Listing
September 2019

User perspectives on a psychosocial blended support program for partners of patients with amyotrophic lateral sclerosis and progressive muscular atrophy: a qualitative study.

BMC Psychol 2019 Jun 15;7(1):35. Epub 2019 Jun 15.

Center of Excellence in Rehabilitation Medicine, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht University and De Hoogstraat Rehabilitation, Utrecht, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s40359-019-0308-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6570885PMC
June 2019

Accelerometry for remote monitoring of physical activity in amyotrophic lateral sclerosis: a longitudinal cohort study.

J Neurol 2019 Oct 11;266(10):2387-2395. Epub 2019 Jun 11.

Department of Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX, Utrecht, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00415-019-09427-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6765690PMC
October 2019

Natural course of scoliosis and lifetime risk of scoliosis surgery in spinal muscular atrophy.

Neurology 2019 07 4;93(2):e149-e158. Epub 2019 Jun 4.

From the Department of Neurology and Neurosurgery (C.A.W., F.A.S.d.K., M.S., L.A.M.O., F.-L.A., R.P.A.v.E., J.S., I.C., L.H.v.d.B., R.I.W., W-L.v.d.P), Department of Rehabilitation (M.V.), Department of Orthopedic Surgery (R.C.B., R.M.C.), Department of Pediatrics, Child Development and Exercise Centre (B.B), and Biostatistics & Research Support Julius Centre for Health Sciences and Primary Care (R.P.A.v.E.), University Medical Centre Utrecht, Utrecht University, the Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1212/WNL.0000000000007742DOI Listing
July 2019

Loss of appetite is associated with a loss of weight and fat mass in patients with amyotrophic lateral sclerosis.

Amyotroph Lateral Scler Frontotemporal Degener 2019 11 30;20(7-8):497-505. Epub 2019 May 30.

Australian Institute for Bioengineering and Nanotechnology, The University of Queensland , Brisbane , Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/21678421.2019.1621346DOI Listing
November 2019

A neuropsychological and behavioral study of PLS.

Amyotroph Lateral Scler Frontotemporal Degener 2019 08 28;20(5-6):376-384. Epub 2019 May 28.

a Department of Neurology , Brain Center Rudolf Magnus, University Medical Center Utrecht , Utrecht , the Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/21678421.2019.1620284DOI Listing
August 2019

10Kin1day: A Bottom-Up Neuroimaging Initiative.

Authors:
Martijn P van den Heuvel Lianne H Scholtens Hannelore K van der Burgh Federica Agosta Clara Alloza Celso Arango Bonnie Auyeung Simon Baron-Cohen Silvia Basaia Manon J N L Benders Frauke Beyer Linda Booij Kees P J Braun Geraldo Busatto Filho Wiepke Cahn Dara M Cannon Tiffany M Chaim-Avancini Sandra S M Chan Eric Y H Chen Benedicto Crespo-Facorro Eveline A Crone Udo Dannlowski Sonja M C de Zwarte Bruno Dietsche Gary Donohoe Stefan Du Plessis Sarah Durston Covadonga M Díaz-Caneja Ana M Díaz-Zuluaga Robin Emsley Massimo Filippi Thomas Frodl Martin Gorges Beata Graff Dominik Grotegerd Dariusz Gąsecki Julie M Hall Laurena Holleran Rosemary Holt Helene J Hopman Andreas Jansen Joost Janssen Krzysztof Jodzio Lutz Jäncke Vasiliy G Kaleda Jan Kassubek Shahrzad Kharabian Masouleh Tilo Kircher Martijn G J C Koevoets Vladimir S Kostic Axel Krug Stephen M Lawrie Irina S Lebedeva Edwin H M Lee Tristram A Lett Simon J G Lewis Franziskus Liem Michael V Lombardo Carlos Lopez-Jaramillo Daniel S Margulies Sebastian Markett Paulo Marques Ignacio Martínez-Zalacaín Colm McDonald Andrew M McIntosh Genevieve McPhilemy Susanne L Meinert José M Menchón Christian Montag Pedro S Moreira Pedro Morgado David O Mothersill Susan Mérillat Hans-Peter Müller Leila Nabulsi Pablo Najt Krzysztof Narkiewicz Patrycja Naumczyk Bob Oranje Victor Ortiz-Garcia de la Foz Jiska S Peper Julian A Pineda Paul E Rasser Ronny Redlich Jonathan Repple Martin Reuter Pedro G P Rosa Amber N V Ruigrok Agnieszka Sabisz Ulrich Schall Soraya Seedat Mauricio H Serpa Stavros Skouras Carles Soriano-Mas Nuno Sousa Edyta Szurowska Alexander S Tomyshev Diana Tordesillas-Gutierrez Sofie L Valk Leonard H van den Berg Theo G M van Erp Neeltje E M van Haren Judith M C van Leeuwen Arno Villringer Christiaan H Vinkers Christian Vollmar Lea Waller Henrik Walter Heather C Whalley Marta Witkowska A Veronica Witte Marcus V Zanetti Rui Zhang Siemon C de Lange

Front Neurol 2019 9;10:425. Epub 2019 May 9.

Connectome Lab, CTG, CNCR, VU Amsterdam, Amsterdam, Netherlands.

View Article

Download full-text PDF

Source
https://www.frontiersin.org/article/10.3389/fneur.2019.00425
Publisher Site
http://dx.doi.org/10.3389/fneur.2019.00425DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6524614PMC
May 2019

Two heads are better than one: benefits of joint models for ALS trials.

J Neurol Neurosurg Psychiatry 2019 09 11;90(9):1071-1072. Epub 2019 Apr 11.

Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, The Netherlands.

View Article

Download full-text PDF

Source
http://jnnp.bmj.com/lookup/doi/10.1136/jnnp-2019-320553
Publisher Site
http://dx.doi.org/10.1136/jnnp-2019-320553DOI Listing
September 2019

Occupation and motor neuron disease: a New Zealand case-control study.

Occup Environ Med 2019 05 22;76(5):309-316. Epub 2019 Mar 22.

Centre for Public Health Research, Massey University, Wellington, New Zealand.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/oemed-2018-105605DOI Listing
May 2019

Multicentre, population-based, case-control study of particulates, combustion products and amyotrophic lateral sclerosis risk.

J Neurol Neurosurg Psychiatry 2019 08 8;90(8):854-860. Epub 2019 Mar 8.

Department of Neurology, Brain Centre Rudolf Magnus, University Medical Centre Utrecht, Utrecht, The Netherlands

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/jnnp-2018-319779DOI Listing
August 2019

Revised Airlie House consensus guidelines for design and implementation of ALS clinical trials.

Neurology 2019 04 8;92(14):e1610-e1623. Epub 2019 Mar 8.

From the Department of Neurology (L.H.v.d.B.), Brain Center Rudolf Magnus, University Medical Center Utrecht, the Netherlands; Department of Neurology (E.S.), Mayo Clinic, Rochester, MN; Department of Neurology (G.G.), University of Kansas Medical Center, Kansas City; Department of Medicine (E.A.M.), Massachusetts General Hospital, Biostatistics Center, Harvard Medical School, Boston; Department of Neurology (J.A., H.M.), Columbia University, Eleanor and Lou Gehrig ALS Center, New York, NY; Department of Neurology (R.H.B.), Cedars-Sinai Medical Center, Los Angeles, CA; Department of Neurology (M.B.), University of Miami, FL; Neurological Clinical Research Institute (J.D.B.), Massachusetts General Hospital, Boston; Rita Levi Montalcini Department of Neuroscience (A.C.), University of Torino, Italy; Centre Constitutif SLA (P.C.), Université de Tours, France; Department of Neurology (A.G.), Clinical Research Unit, Montreal Neurological Institute, Neurosurgery, McGill University, Montreal, Canada; National Institute of Neurological Disorders and Stroke (A.K.G.), National Institutes of Health, Bethesda, MD; ALS Center (C.L.-H.), University of California San Francisco; Department of Neuroscience (C.J.M.), Sheffield Institute for Translational Neuroscience, University of Sheffield, UK; Department of Neurology (E.P.P.), Section of ALS & Related Disorders, Cleveland Clinic, OH; Department of Neurology (J.R.), The Center for Restorative Neurology, Loma Linda University School of Medicine, CA; Department of Neurology and Laboratory of Neuroscience (V.S.), Istituto Auxologico Italiano, IRCCS, Milan; Department of Pathophysiology and Transplantation (V.S.), "Dino Ferrari" Centre, Università degli Studi di Milano, Milan, Italy; Nuffield Department of Clinical Neurosciences (M.R.T.), University of Oxford, UK; Neuromuscular Diseases Unit/ALS Clinic (M.W.), Kantonsspital St. Gallen, Switzerland; Carolinas Neuromuscular/ALS-MDA Care Center (B.R.B.), Charlotte; Department of Neurology (B.R.B.), Carolinas Medical Center, University of North Carolina School of Medicine, Charlotte; Forbes Norris ALS Treatment and Research Center (R.G.M.), California Pacific Medical Center San Francisco; and Department of Neurosciences (R.G.M.), Stanford University, CA.

View Article

Download full-text PDF

Source
http://www.neurology.org/lookup/doi/10.1212/WNL.000000000000
Publisher Site
http://dx.doi.org/10.1212/WNL.0000000000007242DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448453PMC
April 2019

Serum cytokine patterns in immunoglobulin m monoclonal gammopathy-associated polyneuropathy.

Muscle Nerve 2019 06 22;59(6):694-698. Epub 2019 Mar 22.

Department of Neurology and Neurosurgery, Brain Center Rudolf Magnus, University Medical Center, Utrecht, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/mus.26462DOI Listing
June 2019

Evidence for a multimodal effect of riluzole in patients with ALS?

J Neurol Neurosurg Psychiatry 2019 10 7;90(10):1183-1184. Epub 2019 Mar 7.

Neurology, Brain Centre Rudolf Magnus, University Medical Centre Utrecht, Utrecht, The Netherlands

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/jnnp-2018-320211DOI Listing
October 2019

Statins do not increase risk of polyneuropathy: A case-control study and literature review.

Neurology 2019 04 8;92(18):e2136-e2144. Epub 2019 Feb 8.

From the UMC Utrecht Brain Center (J.K.W., A.F.J.E.V., N.A.V., L.H.v.d.B., N.C.N.), Department of Neurology, UMC Utrecht; and Biostatistics & Research Support (R.P.A.v.E.), Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, the Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1212/WNL.0000000000007148DOI Listing
April 2019

Psychological distress and coping styles of caregivers of patients with amyotrophic lateral sclerosis: a longitudinal study.

Amyotroph Lateral Scler Frontotemporal Degener 2019 05 18;20(3-4):235-241. Epub 2019 Jan 18.

a Center of Excellence for Rehabilitation Medicine , Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht University and De Hoogstraat Rehabilitation , Utrecht , The Netherlands.

View Article

Download full-text PDF

Source
https://www.tandfonline.com/doi/full/10.1080/21678421.2018.1
Publisher Site
http://dx.doi.org/10.1080/21678421.2018.1534976DOI Listing
May 2019

Refining eligibility criteria for amyotrophic lateral sclerosis clinical trials.

Neurology 2019 Jan 9. Epub 2019 Jan 9.

From the Department of Neurology (R.P.A.v.E., H.-J.W., I.E.V., M.A.v.E., L.H.v.d.B.), Brain Center Rudolf Magnus, and Biostatistics & Research Support (R.P.A.v.E., S.N., M.J.C.E.), Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, the Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1212/WNL.0000000000006855DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369899PMC
January 2019

Nerve ultrasound: A reproducible diagnostic tool in peripheral neuropathy.

Neurology 2018 Dec 28. Epub 2018 Dec 28.

From the Department of Neurology and Clinical Neurophysiology (J.A.T., I.J.T.H., J.-T.H.v.A., L.H.V.), Elisabeth-Tweesteden Hospital, Tilburg; Department of Neurology and Neurosurgery (J.A.T., I.J.T.H., H.S.G., W.L.v.d.P., L.H.v.d.B.), Brain Center Rudolf Magnus, UMC Utrecht; Department of Neurology and Clinical Neurophysiology (C.V.), Academic Medical Center, Amsterdam; and Department of Biostatistics (S.N.), Julius Center for Health Sciences and Primary Care, UMC Utrecht, the Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1212/WNL.0000000000006856DOI Listing
December 2018

Association of maternal prenatal smoking GFI1-locus and cardio-metabolic phenotypes in 18,212 adults.

EBioMedicine 2018 Dec 13;38:206-216. Epub 2018 Nov 13.

Center for Life Course Health Research, University of Oulu, Oulu, Finland; Biocenter Oulu, University of Oulu, Oulu, Finland; Medical Research Centre (MRC) Oulu, Oulu University Hospital, University of Oulu, Oulu, Finland. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S23523964183048
Publisher Site
http://dx.doi.org/10.1016/j.ebiom.2018.10.066DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306313PMC
December 2018

Derivation of norms for the Dutch version of the Edinburgh cognitive and behavioral ALS screen.

Amyotroph Lateral Scler Frontotemporal Degener 2019 02 12;20(1-2):19-27. Epub 2018 Oct 12.

a Department of Neurology , Brain Centre Rudolf Magnus, University Medical Centre Utrecht , Utrecht , The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/21678421.2018.1522352DOI Listing
February 2019

Microglia innately develop within cerebral organoids.

Nat Commun 2018 10 9;9(1):4167. Epub 2018 Oct 9.

Department of Translational Neuroscience, Brain Center Rudolf Magnus, University Medical Center Utrecht (BCRM-UMCU), Utrecht University, P.O. Box 85500, Universiteitsweg 100, 3584 CG, Utrecht, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41467-018-06684-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6177485PMC
October 2018

A continuous repetitive task to detect fatigability in spinal muscular atrophy.

Orphanet J Rare Dis 2018 09 12;13(1):160. Epub 2018 Sep 12.

Department of Neurology, Brain Center Rudolf Magnus Institute of Neuroscience, Utrecht University, University Medical Center Utrecht, Heidelberglaan 100, F02.230, 3508 GA, Utrecht, The Netherlands.

View Article

Download full-text PDF

Source
https://ojrd.biomedcentral.com/articles/10.1186/s13023-018-0
Publisher Site
http://dx.doi.org/10.1186/s13023-018-0904-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6134509PMC
September 2018

Nerve ultrasound and magnetic resonance imaging in the diagnosis of neuropathy.

Curr Opin Neurol 2018 10;31(5):526-533

Brain Center Rudolf Magnus, Department of Neurology and Neurosurgery.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/WCO.0000000000000607DOI Listing
October 2018

Association between alcohol exposure and the risk of amyotrophic lateral sclerosis in the Euro-MOTOR study.

J Neurol Neurosurg Psychiatry 2019 01 3;90(1):11-19. Epub 2018 Aug 3.

'Rita Levi Montalcini' Department of Neurosciences, University of Turin, Turin, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/jnnp-2018-318559DOI Listing
January 2019

Cognitive and behavioural changes in PLS and PMA:challenging the concept of restricted phenotypes.

J Neurol Neurosurg Psychiatry 2019 02 3;90(2):141-147. Epub 2018 Aug 3.

Department of Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, The Netherlands

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/jnnp-2018-318788DOI Listing
February 2019

The multistep hypothesis of ALS revisited: The role of genetic mutations.

Neurology 2018 08 25;91(7):e635-e642. Epub 2018 Jul 25.

From the "Rita Levi Montalcini" Department of Neuroscience (A. Chiò, A. Canosa, C.M., U.M., M.B., M.B., A. Calvo), University of Torino; Institute of Cognitive Sciences and Technologies (A. Chiò), National Research Council, Rome; ALS Center (L.M., E.B.), Department of Neurology, Azienda Ospedaliera Universitaria Maggiore della Carità; Department of Health Sciences (S.D., L.C.), Interdisciplinary Research Center of Autoimmune Diseases, "Amedeo Avogadro" University of Eastern Piedmont, Novara, Italy; Department of Medical Statistics (N.P.), London School of Hygiene and Tropical Medicine, UK; Centre for Public Health Research (N.P.), Massey University Wellington Campus, New Zealand; Department of Neurology and Neurosurgery (J.H.V., L.H.v.d.B.), Brain Center Rudolf Magnus, University Medical Center Utrecht, the Netherlands; Academic Unit of Neurology (R.M., A.V., O.H., J.R.), Trinity Biomedical Sciences Institute, Trinity College Dublin, Ireland; Istituti Clinici Scientifici Maugeri (G.M.), IRCCS Milano, Italy (Gabriele Mora); and King's College London (W.S., A.A.-C.), Institute of Psychiatry, Psychology and Neuroscience, Maurice Wohl Clinical Neuroscience Institute, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1212/WNL.0000000000005996DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6105040PMC
August 2018

The life expectancy of Stephen Hawking, according to the ENCALS model.

Lancet Neurol 2018 08 17;17(8):662-663. Epub 2018 Jul 17.

Department of Neurology, Brain Centre Rudolf Magnus, University Medical Centre Utrecht, Utrecht 3584 CX, Netherlands. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/S1474-4422(18)30241-2DOI Listing
August 2018

Social participation of adult patients with spinal muscular atrophy: Frequency, restrictions, satisfaction, and correlates.

Muscle Nerve 2018 12 15;58(6):805-811. Epub 2018 Nov 15.

Center of Excellence for Rehabilitation Medicine, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht University and De Hoogstraat Rehabilitation, Utrecht, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/mus.26201DOI Listing
December 2018

Long-Term Air Pollution Exposure and Amyotrophic Lateral Sclerosis in Netherlands: A Population-based Case-control Study.

Environ Health Perspect 2017 09 27;125(9):097023. Epub 2017 Sep 27.

Environmental Epidemiology Division, Institute for Risk Assessment Sciences, Utrecht University, Utrecht, Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1289/EHP1115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915195PMC
September 2017

A blended psychosocial support program for partners of patients with amyotrophic lateral sclerosis and progressive muscular atrophy: protocol of a randomized controlled trial.

BMC Psychol 2018 May 2;6(1):20. Epub 2018 May 2.

Center of Excellence in Rehabilitation Medicine, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht University and De Hoogstraat Rehabilitation, Utrecht, the Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s40359-018-0232-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5930742PMC
May 2018

Multicentre, cross-cultural, population-based, case-control study of physical activity as risk factor for amyotrophic lateral sclerosis.

J Neurol Neurosurg Psychiatry 2018 08 23;89(8):797-803. Epub 2018 Apr 23.

Department of Neurology, Brain Centre Rudolf Magnus, University Medical Centre Utrecht, Utrecht, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/jnnp-2017-317724DOI Listing
August 2018

Understanding the use of NIV in ALS: results of an international ALS specialist survey.

Amyotroph Lateral Scler Frontotemporal Degener 2018 08 16;19(5-6):331-341. Epub 2018 Apr 16.

k Department of Neurology, Brain Centre Rudolf Magnus , University Medical Centre Utrecht , Utrecht , The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/21678421.2018.1457058DOI Listing
August 2018

Author Correction: A replication study of genetic risk loci for ischemic stroke in a Dutch population: a case-control study.

Sci Rep 2018 Apr 11;8(1):6057. Epub 2018 Apr 11.

Department of Neurology and Neurosurgery, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41598-018-22952-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895799PMC
April 2018

"ALS reversals": demographics, disease characteristics, treatments, and co-morbidities.

Amyotroph Lateral Scler Frontotemporal Degener 2018 11 2;19(7-8):495-499. Epub 2018 Apr 2.

f Department of Neurology , Duke University and Durham VA Medical Center , Durham , NC , USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/21678421.2018.1457059DOI Listing
November 2018