Leonard Lipovich

Leonard Lipovich

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Leonard Lipovich

Leonard Lipovich

Publications by authors named "Leonard Lipovich"

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The Growth-Arrest-Specific ()-5 Long Non-Coding RNA: A Fascinating lncRNA Widely Expressed in Cancers.

Noncoding RNA 2019 Sep 17;5(3). Epub 2019 Sep 17.

Center for Molecular Medicine and Genetics, Wayne State University School of Medicine, Detroit, MI 48201, USA.

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https://www.mdpi.com/2311-553X/5/3/46
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http://dx.doi.org/10.3390/ncrna5030046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6789762PMC
September 2019

Unintended target effect of anti-BCL-2 DNAi.

Cancer Manag Res 2017 22;9:427-432. Epub 2017 Sep 22.

Lymphoma Research Laboratory.

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http://dx.doi.org/10.2147/CMAR.S139105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5624602PMC
September 2017

Meta-Analysis of Genome-Wide Association Studies for Abdominal Aortic Aneurysm Identifies Four New Disease-Specific Risk Loci.

Authors:
Gregory T Jones Gerard Tromp Helena Kuivaniemi Solveig Gretarsdottir Annette F Baas Betti Giusti Ewa Strauss Femke N G Van't Hof Thomas R Webb Robert Erdman Marylyn D Ritchie James R Elmore Anurag Verma Sarah Pendergrass Iftikhar J Kullo Zi Ye Peggy L Peissig Omri Gottesman Shefali S Verma Jennifer Malinowski Laura J Rasmussen-Torvik Kenneth M Borthwick Diane T Smelser David R Crosslin Mariza de Andrade Evan J Ryer Catherine A McCarty Erwin P Böttinger Jennifer A Pacheco Dana C Crawford David S Carrell Glenn S Gerhard David P Franklin David J Carey Victoria L Phillips Michael J A Williams Wenhua Wei Ross Blair Andrew A Hill Thodor M Vasudevan David R Lewis Ian A Thomson Jo Krysa Geraldine B Hill Justin Roake Tony R Merriman Grzegorz Oszkinis Silvia Galora Claudia Saracini Rosanna Abbate Raffaele Pulli Carlo Pratesi Athanasios Saratzis Ana R Verissimo Suzannah Bumpstead Stephen A Badger Rachel E Clough Gillian Cockerill Hany Hafez D Julian A Scott T Simon Futers Simon P R Romaine Katherine Bridge Kathryn J Griffin Marc A Bailey Alberto Smith Matthew M Thompson Frank M van Bockxmeer Stefan E Matthiasson Gudmar Thorleifsson Unnur Thorsteinsdottir Jan D Blankensteijn Joep A W Teijink Cisca Wijmenga Jacqueline de Graaf Lambertus A Kiemeney Jes S Lindholt Anne Hughes Declan T Bradley Kathleen Stirrups Jonathan Golledge Paul E Norman Janet T Powell Steve E Humphries Stephen E Hamby Alison H Goodall Christopher P Nelson Natzi Sakalihasan Audrey Courtois Robert E Ferrell Per Eriksson Lasse Folkersen Anders Franco-Cereceda John D Eicher Andrew D Johnson Christer Betsholtz Arno Ruusalepp Oscar Franzén Eric E Schadt Johan L M Björkegren Leonard Lipovich Anne M Drolet Eric L Verhoeven Clark J Zeebregts Robert H Geelkerken Marc R van Sambeek Steven M van Sterkenburg Jean-Paul de Vries Kari Stefansson John R Thompson Paul I W de Bakker Panos Deloukas Robert D Sayers Seamus C Harrison Andre M van Rij Nilesh J Samani Matthew J Bown

Circ Res 2017 Jan 29;120(2):341-353. Epub 2016 Nov 29.

For the author affiliations, please see the Appendix.

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http://dx.doi.org/10.1161/CIRCRESAHA.116.308765DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5253231PMC
January 2017

Trans-ethnic Meta-analysis and Functional Annotation Illuminates the Genetic Architecture of Fasting Glucose and Insulin.

Authors:
Ching-Ti Liu Sridharan Raghavan Nisa Maruthur Edmond Kato Kabagambe Jaeyoung Hong Maggie C Y Ng Marie-France Hivert Yingchang Lu Ping An Amy R Bentley Anne M Drolet Kyle J Gaulton Xiuqing Guo Loren L Armstrong Marguerite R Irvin Man Li Leonard Lipovich Denis V Rybin Kent D Taylor Charles Agyemang Nicholette D Palmer Brian E Cade Wei-Min Chen Marco Dauriz Joseph A C Delaney Todd L Edwards Daniel S Evans Michele K Evans Leslie A Lange Aaron Leong Jingmin Liu Yongmei Liu Uma Nayak Sanjay R Patel Bianca C Porneala Laura J Rasmussen-Torvik Marieke B Snijder Sarah C Stallings Toshiko Tanaka Lisa R Yanek Wei Zhao Diane M Becker Lawrence F Bielak Mary L Biggs Erwin P Bottinger Donald W Bowden Guanjie Chen Adolfo Correa David J Couper Dana C Crawford Mary Cushman John D Eicher Myriam Fornage Nora Franceschini Yi-Ping Fu Mark O Goodarzi Omri Gottesman Kazuo Hara Tamara B Harris Richard A Jensen Andrew D Johnson Min A Jhun Andrew J Karter Margaux F Keller Abel N Kho Jorge R Kizer Ronald M Krauss Carl D Langefeld Xiaohui Li Jingling Liang Simin Liu William L Lowe Thomas H Mosley Kari E North Jennifer A Pacheco Patricia A Peyser Alan L Patrick Kenneth M Rice Elizabeth Selvin Mario Sims Jennifer A Smith Salman M Tajuddin Dhananjay Vaidya Mary P Wren Jie Yao Xiaofeng Zhu Julie T Ziegler Joseph M Zmuda Alan B Zonderman Aeilko H Zwinderman Adebowale Adeyemo Eric Boerwinkle Luigi Ferrucci M Geoffrey Hayes Sharon L R Kardia Iva Miljkovic James S Pankow Charles N Rotimi Michele M Sale Lynne E Wagenknecht Donna K Arnett Yii-Der Ida Chen Michael A Nalls Michael A Province W H Linda Kao David S Siscovick Bruce M Psaty James G Wilson Ruth J F Loos Josée Dupuis Stephen S Rich Jose C Florez Jerome I Rotter Andrew P Morris James B Meigs

Am J Hum Genet 2016 Jul 16;99(1):56-75. Epub 2016 Jun 16.

Division of General Internal Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2016.05.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5005440PMC
July 2016

Promoter analysis reveals globally differential regulation of human long non-coding RNA and protein-coding genes.

PLoS One 2014 2;9(10):e109443. Epub 2014 Oct 2.

King Abdullah University of Science and Technology (KAUST), Computational Bioscience Research Center (CBRC), Computer, Electrical and Mathematical Sciences and Engineering Division (CEMSE), Thuwal, Saudi Arabia.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0109443PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4183604PMC
December 2015

Identification of long noncoding RNAs dysregulated in the midbrain of human cocaine abusers.

J Neurochem 2015 Oct 1;135(1):50-9. Epub 2015 Sep 1.

Department of Pharmacology, Wayne State University School of Medicine, Detroit, Michigan, USA.

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http://dx.doi.org/10.1111/jnc.13255DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4830632PMC
October 2015

Pseudogene-derived lncRNAs: emerging regulators of gene expression.

Front Genet 2014 4;5:476. Epub 2015 Feb 4.

Center for Molecular Medicine and Genetics, Wayne State University School of Medicine , Detroit, MI, USA.

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http://dx.doi.org/10.3389/fgene.2014.00476DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4316772PMC
February 2015

Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility.

Authors:
Jennifer Wessel Audrey Y Chu Sara M Willems Shuai Wang Hanieh Yaghootkar Jennifer A Brody Marco Dauriz Marie-France Hivert Sridharan Raghavan Leonard Lipovich Bertha Hidalgo Keolu Fox Jennifer E Huffman Ping An Yingchang Lu Laura J Rasmussen-Torvik Niels Grarup Margaret G Ehm Li Li Abigail S Baldridge Alena Stančáková Ravinder Abrol Céline Besse Anne Boland Jette Bork-Jensen Myriam Fornage Daniel F Freitag Melissa E Garcia Xiuqing Guo Kazuo Hara Aaron Isaacs Johanna Jakobsdottir Leslie A Lange Jill C Layton Man Li Jing Hua Zhao Karina Meidtner Alanna C Morrison Mike A Nalls Marjolein J Peters Maria Sabater-Lleal Claudia Schurmann Angela Silveira Albert V Smith Lorraine Southam Marcus H Stoiber Rona J Strawbridge Kent D Taylor Tibor V Varga Kristine H Allin Najaf Amin Jennifer L Aponte Tin Aung Caterina Barbieri Nathan A Bihlmeyer Michael Boehnke Cristina Bombieri Donald W Bowden Sean M Burns Yuning Chen Yii-DerI Chen Ching-Yu Cheng Adolfo Correa Jacek Czajkowski Abbas Dehghan Georg B Ehret Gudny Eiriksdottir Stefan A Escher Aliki-Eleni Farmaki Mattias Frånberg Giovanni Gambaro Franco Giulianini William A Goddard Anuj Goel Omri Gottesman Megan L Grove Stefan Gustafsson Yang Hai Göran Hallmans Jiyoung Heo Per Hoffmann Mohammad K Ikram Richard A Jensen Marit E Jørgensen Torben Jørgensen Maria Karaleftheri Chiea C Khor Andrea Kirkpatrick Aldi T Kraja Johanna Kuusisto Ethan M Lange I T Lee Wen-Jane Lee Aaron Leong Jiemin Liao Chunyu Liu Yongmei Liu Cecilia M Lindgren Allan Linneberg Giovanni Malerba Vasiliki Mamakou Eirini Marouli Nisa M Maruthur Angela Matchan Roberta McKean-Cowdin Olga McLeod Ginger A Metcalf Karen L Mohlke Donna M Muzny Ioanna Ntalla Nicholette D Palmer Dorota Pasko Andreas Peter Nigel W Rayner Frida Renström Ken Rice Cinzia F Sala Bengt Sennblad Ioannis Serafetinidis Jennifer A Smith Nicole Soranzo Elizabeth K Speliotes Eli A Stahl Kathleen Stirrups Nikos Tentolouris Anastasia Thanopoulou Mina Torres Michela Traglia Emmanouil Tsafantakis Sundas Javad Lisa R Yanek Eleni Zengini Diane M Becker Joshua C Bis James B Brown L Adrienne Cupples Torben Hansen Erik Ingelsson Andrew J Karter Carlos Lorenzo Rasika A Mathias Jill M Norris Gina M Peloso Wayne H-H Sheu Daniela Toniolo Dhananjay Vaidya Rohit Varma Lynne E Wagenknecht Heiner Boeing Erwin P Bottinger George Dedoussis Panos Deloukas Ele Ferrannini Oscar H Franco Paul W Franks Richard A Gibbs Vilmundur Gudnason Anders Hamsten Tamara B Harris Andrew T Hattersley Caroline Hayward Albert Hofman Jan-Håkan Jansson Claudia Langenberg Lenore J Launer Daniel Levy Ben A Oostra Christopher J O'Donnell Stephen O'Rahilly Sandosh Padmanabhan James S Pankow Ozren Polasek Michael A Province Stephen S Rich Paul M Ridker Igor Rudan Matthias B Schulze Blair H Smith André G Uitterlinden Mark Walker Hugh Watkins Tien Y Wong Eleftheria Zeggini Markku Laakso Ingrid B Borecki Daniel I Chasman Oluf Pedersen Bruce M Psaty E Shyong Tai Cornelia M van Duijn Nicholas J Wareham Dawn M Waterworth Eric Boerwinkle W H Linda Kao Jose C Florez Ruth J F Loos James G Wilson Timothy M Frayling David S Siscovick Josée Dupuis Jerome I Rotter James B Meigs Robert A Scott Mark O Goodarzi

Nat Commun 2015 Jan 29;6:5897. Epub 2015 Jan 29.

1] Department of Medicine and Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, California 90048, USA [2] Division of Endocrinology, Diabetes and Metabolism, Cedars-Sinai Medical Center, Los Angeles, California 90048, USA.

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http://dx.doi.org/10.1038/ncomms6897DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4311266PMC
January 2015

Anti-centrosome antibodies in breast cancer are the expression of autoimmunity.

Immunol Res 2014 Dec;60(2-3):339-47

Division of Rheumatology, Department of Internal Medicine, Wayne State University School of Medicine, 540 Canfield, Detroit, MI, 48201, USA,

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http://dx.doi.org/10.1007/s12026-014-8582-4DOI Listing
December 2014

Reply to Skoyles: Decline in growth rate, not muscle mass, predicts the human childhood peak in brain metabolism.

Proc Natl Acad Sci U S A 2014 Nov 10;111(46):E4910. Epub 2014 Nov 10.

Departments of Psychiatry and Biostatistics, Harvard University and McLean Hospital, Cambridge, MA 02138.

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http://dx.doi.org/10.1073/pnas.1418398111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4246347PMC
November 2014

Transcriptome interrogation of human myometrium identifies differentially expressed sense-antisense pairs of protein-coding and long non-coding RNA genes in spontaneous labor at term.

J Matern Fetal Neonatal Med 2014 Sep 13;27(14):1397-408. Epub 2014 Jan 13.

Perinatology Research Branch, Program for Perinatal Research and Obstetrics, Division of Intramural Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH , Bethesda, MD and Detroit, MI , USA .

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http://dx.doi.org/10.3109/14767058.2013.860963DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4208830PMC
September 2014

Metabolic costs and evolutionary implications of human brain development.

Proc Natl Acad Sci U S A 2014 Sep 25;111(36):13010-5. Epub 2014 Aug 25.

Department of Psychiatry and Department of Biostatistics, Harvard University and McLean Hospital, Cambridge, MA 02138.

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http://dx.doi.org/10.1073/pnas.1323099111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4246958PMC
September 2014

Evolutionary conservation of long non-coding RNAs; sequence, structure, function.

Biochim Biophys Acta 2014 Mar 27;1840(3):1063-71. Epub 2013 Oct 27.

School of Biotechnology and Biomolecular Sciences, The University of New South Wales, Sydney, Australia; Department of Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, CA, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S03044165130047
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http://dx.doi.org/10.1016/j.bbagen.2013.10.035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909678PMC
March 2014

A promoter-level mammalian expression atlas.

Authors:
Alistair R R Forrest Hideya Kawaji Michael Rehli J Kenneth Baillie Michiel J L de Hoon Vanja Haberle Timo Lassmann Ivan V Kulakovskiy Marina Lizio Masayoshi Itoh Robin Andersson Christopher J Mungall Terrence F Meehan Sebastian Schmeier Nicolas Bertin Mette Jørgensen Emmanuel Dimont Erik Arner Christian Schmidl Ulf Schaefer Yulia A Medvedeva Charles Plessy Morana Vitezic Jessica Severin Colin A Semple Yuri Ishizu Robert S Young Margherita Francescatto Intikhab Alam Davide Albanese Gabriel M Altschuler Takahiro Arakawa John A C Archer Peter Arner Magda Babina Sarah Rennie Piotr J Balwierz Anthony G Beckhouse Swati Pradhan-Bhatt Judith A Blake Antje Blumenthal Beatrice Bodega Alessandro Bonetti James Briggs Frank Brombacher A Maxwell Burroughs Andrea Califano Carlo V Cannistraci Daniel Carbajo Yun Chen Marco Chierici Yari Ciani Hans C Clevers Emiliano Dalla Carrie A Davis Michael Detmar Alexander D Diehl Taeko Dohi Finn Drabløs Albert S B Edge Matthias Edinger Karl Ekwall Mitsuhiro Endoh Hideki Enomoto Michela Fagiolini Lynsey Fairbairn Hai Fang Mary C Farach-Carson Geoffrey J Faulkner Alexander V Favorov Malcolm E Fisher Martin C Frith Rie Fujita Shiro Fukuda Cesare Furlanello Masaaki Furino Jun-ichi Furusawa Teunis B Geijtenbeek Andrew P Gibson Thomas Gingeras Daniel Goldowitz Julian Gough Sven Guhl Reto Guler Stefano Gustincich Thomas J Ha Masahide Hamaguchi Mitsuko Hara Matthias Harbers Jayson Harshbarger Akira Hasegawa Yuki Hasegawa Takehiro Hashimoto Meenhard Herlyn Kelly J Hitchens Shannan J Ho Sui Oliver M Hofmann Ilka Hoof Furni Hori Lukasz Huminiecki Kei Iida Tomokatsu Ikawa Boris R Jankovic Hui Jia Anagha Joshi Giuseppe Jurman Bogumil Kaczkowski Chieko Kai Kaoru Kaida Ai Kaiho Kazuhiro Kajiyama Mutsumi Kanamori-Katayama Artem S Kasianov Takeya Kasukawa Shintaro Katayama Sachi Kato Shuji Kawaguchi Hiroshi Kawamoto Yuki I Kawamura Tsugumi Kawashima Judith S Kempfle Tony J Kenna Juha Kere Levon M Khachigian Toshio Kitamura S Peter Klinken Alan J Knox Miki Kojima Soichi Kojima Naoto Kondo Haruhiko Koseki Shigeo Koyasu Sarah Krampitz Atsutaka Kubosaki Andrew T Kwon Jeroen F J Laros Weonju Lee Andreas Lennartsson Kang Li Berit Lilje Leonard Lipovich Alan Mackay-Sim Ri-ichiroh Manabe Jessica C Mar Benoit Marchand Anthony Mathelier Niklas Mejhert Alison Meynert Yosuke Mizuno David A de Lima Morais Hiromasa Morikawa Mitsuru Morimoto Kazuyo Moro Efthymios Motakis Hozumi Motohashi Christine L Mummery Mitsuyoshi Murata Sayaka Nagao-Sato Yutaka Nakachi Fumio Nakahara Toshiyuki Nakamura Yukio Nakamura Kenichi Nakazato Erik van Nimwegen Noriko Ninomiya Hiromi Nishiyori Shohei Noma Shohei Noma Tadasuke Noazaki Soichi Ogishima Naganari Ohkura Hiroko Ohimiya Hiroshi Ohno Mitsuhiro Ohshima Mariko Okada-Hatakeyama Yasushi Okazaki Valerio Orlando Dmitry A Ovchinnikov Arnab Pain Robert Passier Margaret Patrikakis Helena Persson Silvano Piazza James G D Prendergast Owen J L Rackham Jordan A Ramilowski Mamoon Rashid Timothy Ravasi Patrizia Rizzu Marco Roncador Sugata Roy Morten B Rye Eri Saijyo Antti Sajantila Akiko Saka Shimon Sakaguchi Mizuho Sakai Hiroki Sato Suzana Savvi Alka Saxena Claudio Schneider Erik A Schultes Gundula G Schulze-Tanzil Anita Schwegmann Thierry Sengstag Guojun Sheng Hisashi Shimoji Yishai Shimoni Jay W Shin Christophe Simon Daisuke Sugiyama Takaai Sugiyama Masanori Suzuki Naoko Suzuki Rolf K Swoboda Peter A C 't Hoen Michihira Tagami Naoko Takahashi Jun Takai Hiroshi Tanaka Hideki Tatsukawa Zuotian Tatum Mark Thompson Hiroo Toyodo Tetsuro Toyoda Elvind Valen Marc van de Wetering Linda M van den Berg Roberto Verado Dipti Vijayan Ilya E Vorontsov Wyeth W Wasserman Shoko Watanabe Christine A Wells Louise N Winteringham Ernst Wolvetang Emily J Wood Yoko Yamaguchi Masayuki Yamamoto Misako Yoneda Yohei Yonekura Shigehiro Yoshida Susan E Zabierowski Peter G Zhang Xiaobei Zhao Silvia Zucchelli Kim M Summers Harukazu Suzuki Carsten O Daub Jun Kawai Peter Heutink Winston Hide Tom C Freeman Boris Lenhard Vladimir B Bajic Martin S Taylor Vsevolod J Makeev Albin Sandelin David A Hume Piero Carninci Yoshihide Hayashizaki

Nature 2014 Mar;507(7493):462-70

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http://dx.doi.org/10.1038/nature13182DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4529748PMC
March 2014

Characterization of human cortical gene expression in relation to glucose utilization.

Am J Hum Biol 2013 May-Jun;25(3):418-30. Epub 2013 Apr 4.

Center for Molecular Medicine and Genetics, Wayne State University School of Medicine, Detroit, MI 48201, USA.

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http://dx.doi.org/10.1002/ajhb.22394DOI Listing
November 2013

Making sense of Dlx1 antisense RNA.

Dev Biol 2013 Apr 8;376(2):224-35. Epub 2013 Feb 8.

Stem Cell and Developmental Biology, Genome Institute of Singapore, Singapore 138672, Singapore.

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http://dx.doi.org/10.1016/j.ydbio.2013.01.035DOI Listing
April 2013

Challenging paradigms: long non-coding RNAs in breast ductal carcinoma in situ (DCIS).

Front Genet 2013 9;4:50. Epub 2013 Apr 9.

Department of Surgery, Wayne State University School of Medicine Detroit, MI, USA ; Department of Oncology, Karmanos Cancer Institute, Wayne State University School of Medicine Detroit, MI, USA.

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http://dx.doi.org/10.3389/fgene.2013.00050DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3620487PMC
April 2013

MicroRNAs in opioid addiction: elucidating evolution.

Front Genet 2012 26;3:241. Epub 2012 Nov 26.

Center for Molecular Medicine and Genetics, School of Medicine, Wayne State University Detroit, MI, USA.

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http://journal.frontiersin.org/article/10.3389/fgene.2012.00
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http://dx.doi.org/10.3389/fgene.2012.00241DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3516178PMC
December 2012

Tissue-restricted transcription from a conserved intragenic CpG island in the Klf1 gene in mice.

Biol Reprod 2012 Nov 1;87(5):108. Epub 2012 Nov 1.

Center for Molecular Medicine and Genetics, Wayne State University School of Medicine, Detroit, Michigan 48201, USA.

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http://www.biolreprod.org/content/early/2012/08/27/biolrepro
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http://www.biolreprod.org/cgi/doi/10.1095/biolreprod.112.099
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http://dx.doi.org/10.1095/biolreprod.112.099879DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3509778PMC
November 2012

Activity-dependent human brain coding/noncoding gene regulatory networks.

Genetics 2012 Nov 7;192(3):1133-48. Epub 2012 Sep 7.

Center for Molecular Medicine and Genetics, Wayne State University School of Medicine, Detroit, Michigan 48202, USA

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http://www.genetics.org/content/genetics/192/3/1133.full.pdf
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http://www.genetics.org/cgi/doi/10.1534/genetics.112.145128
Publisher Site
http://dx.doi.org/10.1534/genetics.112.145128DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3522156PMC
November 2012

MacroRNA underdogs in a microRNA world: evolutionary, regulatory, and biomedical significance of mammalian long non-protein-coding RNA.

Biochim Biophys Acta 2010 Sep 14;1799(9):597-615. Epub 2010 Oct 14.

Department of Neurology, Wayne State University, Detroit, MI, USA.

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http://dx.doi.org/10.1016/j.bbagrm.2010.10.001DOI Listing
September 2010

Genome-wide computational identification and manual annotation of human long noncoding RNA genes.

RNA 2010 Aug 29;16(8):1478-87. Epub 2010 Jun 29.

Center for Molecular Medicine and Genetics, Wayne State University, Detroit, MO 48202, USA.

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http://rnajournal.cshlp.org/cgi/doi/10.1261/rna.1951310
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http://dx.doi.org/10.1261/rna.1951310DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2905748PMC
August 2010

Conserved long noncoding RNAs transcriptionally regulated by Oct4 and Nanog modulate pluripotency in mouse embryonic stem cells.

RNA 2010 Feb 21;16(2):324-37. Epub 2009 Dec 21.

Stem Cell and Developmental Biology, Genome Institute of Singapore, 138672 Singapore.

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http://dx.doi.org/10.1261/rna.1441510DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2811662PMC
February 2010

Phylogenomic analyses reveal convergent patterns of adaptive evolution in elephant and human ancestries.

Proc Natl Acad Sci U S A 2009 Dec 19;106(49):20824-9. Epub 2009 Nov 19.

Center for Molecular Medicine and Genetics, Department of Anatomy and Cell Biology, Wayne State University School of Medicine, Detroit, MI 48201, USA.

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http://www.pnas.org/cgi/doi/10.1073/pnas.0911239106
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http://dx.doi.org/10.1073/pnas.0911239106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2791620PMC
December 2009

Global discovery of primate-specific genes in the human genome.

Proc Natl Acad Sci U S A 2009 Jul 6;106(29):12019-24. Epub 2009 Jul 6.

Genome Institute of Singapore, 60 Biopolis Street 02-01, 138672 Singapore.

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http://dx.doi.org/10.1073/pnas.0904569106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2715485PMC
July 2009

Sall4 regulates distinct transcription circuitries in different blastocyst-derived stem cell lineages.

Cell Stem Cell 2008 Nov 18;3(5):543-54. Epub 2008 Sep 18.

Stem Cell and Developmental Biology, Genome Institute of Singapore, 138672 Singapore.

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http://dx.doi.org/10.1016/j.stem.2008.08.004DOI Listing
November 2008

Structural differences of orthologous genes: insights from human-primate comparisons.

Genomics 2008 Sep 7;92(3):134-43. Epub 2008 Jul 7.

School of Computer Engineering, Nanyang Technological University, Singapore.

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http://dx.doi.org/10.1016/j.ygeno.2008.05.006DOI Listing
September 2008

Detailed characterization of the mouse embryonic stem cell transcriptome reveals novel genes and intergenic splicing associated with pluripotency.

BMC Genomics 2008 Apr 9;9:155. Epub 2008 Apr 9.

Computational & Mathematical Biology, Genome Institute of Singapore, 60 Biopolis Street #02-01, Singapore 138672, Singapore.

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http://bmcgenomics.biomedcentral.com/articles/10.1186/1471-2
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http://dx.doi.org/10.1186/1471-2164-9-155DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2375908PMC
April 2008

Primate-specific endogenous cis-antisense transcription in the human 5q31 protocadherin gene cluster.

J Mol Evol 2006 Jan 6;62(1):73-88. Epub 2005 Dec 6.

Genome Institute of Singapore, 60 Biopolis Street #02-01, Singapore 138672, Singapore.

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http://link.springer.com/10.1007/s00239-005-0041-3
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http://dx.doi.org/10.1007/s00239-005-0041-3DOI Listing
January 2006

Abundant novel transcriptional units and unconventional gene pairs on human chromosome 22.

Genome Res 2006 Jan 12;16(1):45-54. Epub 2005 Dec 12.

Department of Genome Sciences, University of Washington, Seattle, Washington 98195-7730, USA.

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http://www.genome.org/cgi/doi/10.1101/gr.3883606
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http://dx.doi.org/10.1101/gr.3883606DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1356128PMC
January 2006

Gene identification signature (GIS) analysis for transcriptome characterization and genome annotation.

Nat Methods 2005 Feb 9;2(2):105-11. Epub 2005 Jan 9.

Genome Institute of Singapore, 60 Biopolis Street, Genome 02-01, Singapore 138672.

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http://dx.doi.org/10.1038/nmeth733DOI Listing
February 2005

5' Long serial analysis of gene expression (LongSAGE) and 3' LongSAGE for transcriptome characterization and genome annotation.

Proc Natl Acad Sci U S A 2004 Aug 22;101(32):11701-6. Epub 2004 Jul 22.

Genome Institute of Singapore, 60 Biopolis Street, Genome 02-01, Singapore 138672.

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http://dx.doi.org/10.1073/pnas.0403514101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC511040PMC
August 2004

Pharmaceutical companies need to broaden research.

Authors:
Leonard Lipovich

Drug Discov Today 2003 Jan;8(1):18

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http://dx.doi.org/10.1016/s1359-6446(02)02546-1DOI Listing
January 2003

Comparative genomics comes of age.

Authors:
Leonard Lipovich

Genome Biol 2002 Jul 15;3(8):REPORTS4024. Epub 2002 Jul 15.

Department of Genome Sciences, University of Washington, Seattle, WA 98195-7730, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC139393PMC
http://dx.doi.org/10.1186/gb-2002-3-8-reports4024DOI Listing
July 2002