Leonard I Zon

Leonard I Zon

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Leonard I Zon

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Author Correction: Epoxyeicosatrienoic acids enhance embryonic haematopoiesis and adult marrow engraftment.

Nature 2019 Sep;573(7772):E1

Stem Cell Program and Division of Haematology/Oncology, Boston Children's Hospital and Dana-Farber Cancer Institute, Howard Hughes Medical Institute, Harvard Stem Cell Institute, Harvard Medical School, Boston, MA, 02115, USA.

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http://dx.doi.org/10.1038/s41586-019-1489-4DOI Listing
September 2019

Tumor-Derived Extracellular Vesicles Breach the Intact Blood-Brain Barrier Transcytosis.

ACS Nano 2019 Sep 10. Epub 2019 Sep 10.

Vascular Biology Program , Boston Children's Hospital , Boston , Massachusetts 02115 , United States.

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http://dx.doi.org/10.1021/acsnano.9b04397DOI Listing
September 2019

Neural crest state activation in NRAS driven melanoma, but not in NRAS-driven melanocyte expansion.

Dev Biol 2019 May 5;449(2):107-114. Epub 2018 Jun 5.

Stem Cell Program and Division of Hematology/Oncology, Children's Hospital Boston, Howard Hughes Medical Institute, Boston, MA 02115, USA; Harvard Stem Cell Institute, Boston, MA 02115, USA; Harvard Medical School, Boston, MA 02115, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ydbio.2018.05.026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6281797PMC
May 2019

Estrogen Activation of G-Protein-Coupled Estrogen Receptor 1 Regulates Phosphoinositide 3-Kinase and mTOR Signaling to Promote Liver Growth in Zebrafish and Proliferation of Human Hepatocytes.

Gastroenterology 2019 05 12;156(6):1788-1804.e13. Epub 2019 Jan 12.

Genetics Division, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts; Harvard Stem Cell Institute, Cambridge, Massachusetts; Dana-Farber Cancer Institute, Boston, Massachusetts; Harvard-MIT Division of Health Sciences and Technology, Cambridge, Massachusetts; Broad Institute of MIT and Harvard, Cambridge, Massachusetts; Divison of Gastroenterology, Massachusetts General Hospital, Boston, Massachusetts. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2019.01.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6532055PMC
May 2019

Modeling Cancer with Flies and Fish.

Dev Cell 2019 May;49(3):317-324

Memorial Sloan Kettering Cancer Center, Weill Cornell Medical College, New York, NY, USA. Electronic address:

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http://dx.doi.org/10.1016/j.devcel.2019.04.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6506185PMC
May 2019

Stem cell safe harbor: the hematopoietic stem cell niche in zebrafish.

Blood Adv 2018 11;2(21):3063-3069

Department of Stem Cell and Regenerative Biology and Harvard Stem Cell Institute, Cambridge, MA; and.

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http://dx.doi.org/10.1182/bloodadvances.2018021725DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6234371PMC
November 2018

Zebrafish blastomere screen identifies retinoic acid suppression of in adenoid cystic carcinoma.

J Exp Med 2018 10 12;215(10):2673-2685. Epub 2018 Sep 12.

Stem Cell Program and Division of Hematology/Oncology, Boston Children's Hospital and Dana-Farber Cancer Institute, Howard Hughes Medical Institute, Harvard Stem Cell Institute, Harvard Medical School, Boston, MA

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http://dx.doi.org/10.1084/jem.20180939DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6170170PMC
October 2018

Stu Orkin is a superhero.

Authors:
Leonard I Zon

J Clin Invest 2018 10 1;128(10):4213-4217. Epub 2018 Oct 1.

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http://dx.doi.org/10.1172/JCI124493DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6159974PMC
October 2018

Making HSCs in vitro: don't forget the hemogenic endothelium.

Blood 2018 09 8;132(13):1372-1378. Epub 2018 Aug 8.

Stem Cell Program and Division of Hematology/Oncology, Boston Children's Hospital, Harvard Stem Cell Institute, Howard Hughes Medical Institute, Harvard Medical School, Boston, MA.

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http://dx.doi.org/10.1182/blood-2018-04-784140DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161767PMC
September 2018

Purification of zebrafish erythrocytes as a means of identifying a novel regulator of haematopoiesis.

Br J Haematol 2018 02 19;180(3):420-431. Epub 2017 Dec 19.

Department of Research and Development of Next Generation Medicine, Faculty of Medical Sciences, Kyushu University, Fukuoka, Japan.

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http://dx.doi.org/10.1111/bjh.15048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5977992PMC
February 2018

The histone demethylase Jmjd3 regulates zebrafish myeloid development by promoting spi1 expression.

Biochim Biophys Acta Gene Regul Mech 2018 Feb 31;1861(2):106-116. Epub 2018 Jan 31.

State Key Laboratory for Medical Genomics, Shanghai Institute of Hematology, Collaborative Innovation Center of Hematology, Rui-Jin Hospital affiliated to Shanghai Jiao-Tong University School of Medicine, Shanghai 200025, China; Institute of Health Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences & Shanghai Jiao Tong University School of Medicine, Shanghai 200031, China.

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https://linkinghub.elsevier.com/retrieve/pii/S18749399173030
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http://dx.doi.org/10.1016/j.bbagrm.2017.12.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5972518PMC
February 2018

Targeting the Senescence-Overriding Cooperative Activity of Structurally Unrelated H3K9 Demethylases in Melanoma.

Cancer Cell 2018 02;33(2):322-336.e8

Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association, 13125 Berlin, Germany; Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Medical Department of Hematology, Oncology and Tumor Immunology, Virchow Campus, and Molekulares Krebsforschungszentrum, 13353 Berlin, Germany; Deutsches Konsortium für Translationale Krebsforschung (German Cancer Consortium), Partner Site Berlin, Germany.

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http://dx.doi.org/10.1016/j.ccell.2018.01.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5977991PMC
February 2018

PGE pulsing of murine bone marrow cells reduces migration of daughter monocytes/macrophages in vitro and in vivo.

Exp Hematol 2017 12 16;56:64-68. Epub 2017 Aug 16.

Telethon Kids Institute, University of Western Australia, West Perth, Western Australia, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.exphem.2017.08.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5972521PMC
December 2017

Cancer immunotherapy: The dark side of PD-1 receptor inhibition.

Nature 2017 12 15;552(7683):41-42. Epub 2017 Nov 15.

the Department of Stem Cell and Regenerative Biology, Harvard Stem Cell Institute, Harvard University, Cambridge, Massachusetts 02138, USA.

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http://dx.doi.org/10.1038/nature24759DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6136420PMC
December 2017

KIT Suppresses BRAF-Mutant Melanoma by Attenuating Oncogenic RAS/MAPK Signaling.

Cancer Res 2017 11 25;77(21):5820-5830. Epub 2017 Sep 25.

Program in Molecular Medicine, Department of Molecular, Cell, and Cancer Biology, University of Massachusetts Medical School, Worcester, Massachusetts.

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http://cancerres.aacrjournals.org/lookup/doi/10.1158/0008-54
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http://dx.doi.org/10.1158/0008-5472.CAN-17-0473DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5679278PMC
November 2017

Toddler signaling regulates mesodermal cell migration downstream of Nodal signaling.

Elife 2017 11 9;6. Epub 2017 Nov 9.

Department of Molecular and Cellular Biology, Harvard University, Cambridge, United States.

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http://dx.doi.org/10.7554/eLife.22626DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5679751PMC
November 2017

Efforts to enhance blood stem cell engraftment: Recent insights from zebrafish hematopoiesis.

J Exp Med 2017 Oct 22;214(10):2817-2827. Epub 2017 Aug 22.

Stem Cell Program and Division of Hematology/Oncology, Boston Children's Hospital, Harvard Stem Cell Institute, Harvard Medical School, Boston, MA

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http://dx.doi.org/10.1084/jem.20171069DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626407PMC
October 2017

Fishing for answers in precision cancer medicine.

Proc Natl Acad Sci U S A 2017 09 15;114(39):10306-10308. Epub 2017 Sep 15.

Stem Cell Program and Division of Hematology/Oncology, Boston Children's Hospital and Dana-Farber Cancer Institute, Boston, MA 02115;

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http://dx.doi.org/10.1073/pnas.1713769114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5625937PMC
September 2017

Efficient Transduction of Zebrafish Melanoma Cell Lines and Embryos Using Lentiviral Vectors.

Zebrafish 2017 08 30;14(4):379-382. Epub 2017 May 30.

1 Stem Cell Program, Division of Hematology/Oncology, Boston Children's Hospital , Boston, Massachusetts.

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http://www.liebertpub.com/doi/10.1089/zeb.2017.1434
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http://dx.doi.org/10.1089/zeb.2017.1434DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5549793PMC
August 2017

Blood on the tracks: hematopoietic stem cell-endothelial cell interactions in homing and engraftment.

J Mol Med (Berl) 2017 08 13;95(8):809-819. Epub 2017 Jul 13.

Stem Cell Program and Division of Hematology/Oncology, Boston Children's Hospital, Harvard Stem Cell Institute, Howard Hughes Medical Institute, Harvard Medical School, Boston, MA, 02115, USA.

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http://dx.doi.org/10.1007/s00109-017-1559-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5558790PMC
August 2017

From fish bowl to bedside: The power of zebrafish to unravel melanoma pathogenesis and discover new therapeutics.

Pigment Cell Melanoma Res 2017 07 8;30(4):402-412. Epub 2017 Jun 8.

Stem Cell Program and Division of Hematology/Oncology, Boston Children's Hospital and Dana Farber Cancer Institute, Howard Hughes Medical Institute, Harvard Stem Cell Institute, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1111/pcmr.12592DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6038924PMC
July 2017

Using Zebrafish to Study Pathways that Regulate Hematopoietic Stem Cell Self-Renewal and Migration.

Stem Cell Reports 2017 06;8(6):1465-1471

Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA 02138, USA; Stem Cell Program and Division of Hematology/Oncology, Children's Hospital Boston, Howard Hughes Medical Institute, Boston, MA 02115, USA; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Harvard Stem Cell Institute, Boston, MA 02115, USA; Harvard Medical School, Boston, MA 02115, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2017.05.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5470329PMC
June 2017

Distinct Roles for Matrix Metalloproteinases 2 and 9 in Embryonic Hematopoietic Stem Cell Emergence, Migration, and Niche Colonization.

Stem Cell Reports 2017 05 13;8(5):1226-1241. Epub 2017 Apr 13.

Beth Israel Deaconess Medical Center, Harvard Medical School, Center for Life Sciences, 3 Blackfan Circle, Boston, MA 02115, USA; Harvard Stem Cell Institute, Harvard University, Cambridge, MA 02138, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2017.03.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5425629PMC
May 2017

CXCR1 remodels the vascular niche to promote hematopoietic stem and progenitor cell engraftment.

J Exp Med 2017 04 28;214(4):1011-1027. Epub 2017 Mar 28.

Stem Cell Program and Division of Hematology/Oncology, Boston Children's Hospital and Dana Farber Cancer Institute, Howard Hughes Medical Institute, Harvard Medical School, Harvard Stem Cell Institute, Stem Cell and Regenerative Biology Department, Harvard University, Boston, MA 02138

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http://dx.doi.org/10.1084/jem.20161616DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379982PMC
April 2017

Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis.

Authors:
Frank J A van Rooij Rehan Qayyum Albert V Smith Yi Zhou Stella Trompet Toshiko Tanaka Margaux F Keller Li-Ching Chang Helena Schmidt Min-Lee Yang Ming-Huei Chen James Hayes Andrew D Johnson Lisa R Yanek Christian Mueller Leslie Lange James S Floyd Mohsen Ghanbari Alan B Zonderman J Wouter Jukema Albert Hofman Cornelia M van Duijn Karl C Desch Yasaman Saba Ayse B Ozel Beverly M Snively Jer-Yuarn Wu Reinhold Schmidt Myriam Fornage Robert J Klein Caroline S Fox Koichi Matsuda Naoyuki Kamatani Philipp S Wild David J Stott Ian Ford P Eline Slagboom Jaden Yang Audrey Y Chu Amy J Lambert André G Uitterlinden Oscar H Franco Edith Hofer David Ginsburg Bella Hu Brendan Keating Ursula M Schick Jennifer A Brody Jun Z Li Zhao Chen Tanja Zeller Jack M Guralnik Daniel I Chasman Luanne L Peters Michiaki Kubo Diane M Becker Jin Li Gudny Eiriksdottir Jerome I Rotter Daniel Levy Vera Grossmann Kushang V Patel Chien-Hsiun Chen Paul M Ridker Hua Tang Lenore J Launer Kenneth M Rice Ruifang Li-Gao Luigi Ferrucci Michelle K Evans Avik Choudhuri Eirini Trompouki Brian J Abraham Song Yang Atsushi Takahashi Yoichiro Kamatani Charles Kooperberg Tamara B Harris Sun Ha Jee Josef Coresh Fuu-Jen Tsai Dan L Longo Yuan-Tsong Chen Janine F Felix Qiong Yang Bruce M Psaty Eric Boerwinkle Lewis C Becker Dennis O Mook-Kanamori James G Wilson Vilmundur Gudnason Christopher J O'Donnell Abbas Dehghan L Adrienne Cupples Michael A Nalls Andrew P Morris Yukinori Okada Alexander P Reiner Leonard I Zon Santhi K Ganesh

Am J Hum Genet 2017 Jan 22;100(1):51-63. Epub 2016 Dec 22.

Division of Cardiovascular Medicine, Department of Internal Medicine, Department of Human Genetics, University of Michigan, 1500 E. Medical Center Drive, Ann Arbor, MI 48109, USA. Electronic address:

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http://www.cell.com/ajhg/pdf/S0002-9297(16)30520-1.pdf
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http://linkinghub.elsevier.com/retrieve/pii/S000292971630520
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http://dx.doi.org/10.1016/j.ajhg.2016.11.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5223059PMC
January 2017

Understanding the regulation of vertebrate hematopoiesis and blood disorders - big lessons from a small fish.

FEBS Lett 2016 Nov 25;590(22):4016-4033. Epub 2016 Sep 25.

Howard Hughes Medical Institute, Harvard Stem Cell Institute, Boston Children's Hospital and Harvard Medical School, Boston, MA, USA.

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http://doi.wiley.com/10.1002/1873-3468.12415
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http://dx.doi.org/10.1002/1873-3468.12415DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5483340PMC
November 2016

Development: For cloche the Bell Tolls.

Curr Biol 2016 10 10;26(19):R890-R892. Epub 2016 Oct 10.

Stem Cell Program and Division of Hematology/Oncology, Children's Hospital Boston, Howard Hughes Medical Institute and Harvard Medical School, Boston, MA 02115, USA. Department of Medical Oncology and Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA; Department of Stem Cell and Regenerative Biology and Harvard Stem Cell Institute, Harvard University, Cambridge, MA 02138, USA. Electronic address:

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http://www.cell.com/current-biology/pdf/S0960-9822(16)30921-
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http://dx.doi.org/10.1016/j.cub.2016.08.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6126534PMC
October 2016

Identifying Novel Cancer Therapies Using Chemical Genetics and Zebrafish.

Adv Exp Med Biol 2016 ;916:103-24

Stem Cell Program and Division of Hematology/Oncology, Boston Children's Hospital, Boston, MA, 02115, USA.

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http://link.springer.com/10.1007/978-3-319-30654-4_5
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http://dx.doi.org/10.1007/978-3-319-30654-4_5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022836PMC
September 2016

Long-term drug administration in the adult zebrafish using oral gavage for cancer preclinical studies.

Dis Model Mech 2016 07 11;9(7):811-20. Epub 2016 May 11.

Stem Cell Program and Division of Pediatric Hematology/Oncology, Boston Children's Hospital, Boston, MA 02115, USA Howard Hughes Medical Institute, Boston, MA 02115, USA Harvard Medical School, Boston, MA 02138, USA

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http://dmm.biologists.org/lookup/doi/10.1242/dmm.024166
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http://dx.doi.org/10.1242/dmm.024166DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4958307PMC
July 2016

Engineering Hematopoietic Stem Cells: Lessons from Development.

Cell Stem Cell 2016 06;18(6):707-20

Stem Cell Program and Division of Hematology/Oncology, Boston Children's Hospital, Boston, MA 02115, USA; Howard Hughes Medical Institute, Boston, MA 02115, USA; Harvard Stem Cell Institute, Cambridge, MA 02138, USA; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA; Division of Hematology, Brigham and Women's Hospital, Boston, MA 02115, USA; Manton Center for Orphan Disease Research, Boston, MA 02115, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2016.05.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4911194PMC
June 2016

Generation of Parabiotic Zebrafish Embryos by Surgical Fusion of Developing Blastulae.

J Vis Exp 2016 06 11(112). Epub 2016 Jun 11.

Division of Hematology/Oncology, Boston Children's Hospital; Harvard Medical School; Division of Hematology, Department of Medicine, Brigham and Women's Hospital; Harvard Stem Cell Institute; Broad Institute of Massachusetts Institute of Technology;

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4927786PMC
http://dx.doi.org/10.3791/54168DOI Listing
June 2016

Ex vivo tools for the clonal analysis of zebrafish hematopoiesis.

Nat Protoc 2016 May 28;11(5):1007-20. Epub 2016 Apr 28.

Department of Cell Differentiation, Institute of Molecular Genetics AS CR v.v.i., Prague, Czech Republic.

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http://dx.doi.org/10.1038/nprot.2016.053DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5560128PMC
May 2016

Fish to Learn: Insights into Blood Development and Blood Disorders from Zebrafish Hematopoiesis.

Hum Gene Ther 2016 Apr;27(4):287-94

1 Division of Hematology/Oncology, Boston Children's Hospital and Dana-Farber Cancer Institute , Boston, Massachusetts.

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http://www.liebertpub.com/doi/10.1089/hum.2016.024
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http://dx.doi.org/10.1089/hum.2016.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4841069PMC
April 2016

Insight into GATA1 transcriptional activity through interrogation of cis elements disrupted in human erythroid disorders.

Proc Natl Acad Sci U S A 2016 Apr 4;113(16):4434-9. Epub 2016 Apr 4.

Division of Hematology/Oncology, Manton Center for Orphan Disease Research, Boston Children's Hospital, Boston, MA 02115; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA; 02115; The Broad Institute, Cambridge, MA 02142;

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http://dx.doi.org/10.1073/pnas.1521754113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4843446PMC
April 2016

Stress from Nucleotide Depletion Activates the Transcriptional Regulator HEXIM1 to Suppress Melanoma.

Mol Cell 2016 Apr;62(1):34-46

Howard Hughes Medical Institute, Stem Cell Program and Division of Pediatric Hematology/Oncology, Boston Children's Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02115, USA; Department of Stem Cell and Regenerative Biology, Harvard Stem Cell Institute, Cambridge, MA 02138, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2016.03.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4836061PMC
April 2016

GATA Factor-G-Protein-Coupled Receptor Circuit Suppresses Hematopoiesis.

Stem Cell Reports 2016 Mar 18;6(3):368-82. Epub 2016 Feb 18.

UW-Madison Blood Research Program, Department of Cell and Regenerative Biology, Carbone Cancer Center, University of Wisconsin School of Medicine and Public Health, Madison, WI 53705, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2016.01.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4788764PMC
March 2016

A zebrafish melanoma model reveals emergence of neural crest identity during melanoma initiation.

Science 2016 Jan 28;351(6272):aad2197. Epub 2016 Jan 28.

Stem Cell Program and Division of Hematology/Oncology, Children's Hospital Boston, Howard Hughes Medical Institute, Boston, MA 02115, USA. Harvard Stem Cell Institute, Boston, MA 02115, USA. Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA. Harvard Medical School, Boston, MA 02115, USA. Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA 02138, USA.

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http://dx.doi.org/10.1126/science.aad2197DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4868069PMC
January 2016

A Cdx4-Sall4 regulatory module controls the transition from mesoderm formation to embryonic hematopoiesis.

Stem Cell Reports 2013 7;1(5):425-36. Epub 2013 Nov 7.

Stem Cell Program and Division of Hematology/Oncology, Boston Children's Hospital, Harvard Stem Cell Institute, Harvard Medical School and Howard Hughes Medical Institute, Boston, MA 02115, USA.

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http://dx.doi.org/10.1016/j.stemcr.2013.10.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3841246PMC
October 2015

A non-canonical function of telomerase RNA in the regulation of developmental myelopoiesis in zebrafish.

Nat Commun 2014 ;5:3228

1] Telomerase, Aging and Cancer Group, Research Unit, Department of Surgery, CIBERehd, University Hospital 'Virgen de la Arrixaca', 30120 Murcia, Spain [2] Instituto Murciano de Investigación Biosanitaria (IMIB), 30120 Murcia, Spain.

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http://www.nature.com/articles/ncomms4228
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http://dx.doi.org/10.1038/ncomms4228DOI Listing
October 2015

Mutation of kri1l causes definitive hematopoiesis failure via PERK-dependent excessive autophagy induction.

Cell Res 2015 Aug 3;25(8):946-62. Epub 2015 Jul 3.

1] Key Laboratory of Stem Cell Biology, Institute of Health Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences & Shanghai Jiao Tong University School of Medicine, Shanghai, China [2] Collaborative Innovation Center of Systems Biomedicine, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

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http://dx.doi.org/10.1038/cr.2015.81DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4528055PMC
August 2015

Generation of vascular endothelial and smooth muscle cells from human pluripotent stem cells.

Nat Cell Biol 2015 Aug 27;17(8):994-1003. Epub 2015 Jul 27.

1] Department of Stem Cell and Regenerative Biology and Harvard Stem Cell Institute, Harvard University, Massachusetts 02138, USA [2] Cardiovascular Research Center and Cardiology Division, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA [3] Stem Cell Program and Division of Hematology/Oncology, Boston Children's Hospital and Dana Farber Cancer Institute, Howard Hughes Medical Institute, Harvard Medical School, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1038/ncb3205DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4566857PMC
August 2015

Screening for melanoma resistance genes in vivo.

Pigment Cell Melanoma Res 2015 Jul 13;28(4):375-6. Epub 2015 Apr 13.

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http://doi.wiley.com/10.1111/pcmr.12368
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http://dx.doi.org/10.1111/pcmr.12368DOI Listing
July 2015

TopBP1 Governs Hematopoietic Stem/Progenitor Cells Survival in Zebrafish Definitive Hematopoiesis.

PLoS Genet 2015 Jul 1;11(7):e1005346. Epub 2015 Jul 1.

Key Laboratory of Stem Cell Biology, Institute of Health Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences & Shanghai Jiao Tong University School of Medicine, Shanghai, China.

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http://dx.doi.org/10.1371/journal.pgen.1005346DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4488437PMC
July 2015

Epoxyeicosatrienoic acids enhance embryonic haematopoiesis and adult marrow engraftment.

Nature 2015 Jul;523(7561):468-71

1] Stem Cell Program and Division of Haematology/Oncology, Boston Children's Hospital and Dana-Farber Cancer Institute, Howard Hughes Medical Institute, Harvard Stem Cell Institute, Harvard Medical School, Boston, Massachuestts 02115, USA [2] Chemical Biology Program, Harvard University, Cambridge, Massachusetts 02138, USA.

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http://dx.doi.org/10.1038/nature14569DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754787PMC
July 2015

Adenosine signaling promotes hematopoietic stem and progenitor cell emergence.

J Exp Med 2015 May 13;212(5):649-63. Epub 2015 Apr 13.

Stem Cell Program, Division of Hematology/Oncology, Boston Children's Hospital and Dana-Farber Cancer Institute, Boston, MA 02115 Harvard Stem Cell Institute, Howard Hughes Medical Institute, and Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA 02138 Harvard Stem Cell Institute, Howard Hughes Medical Institute, and Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA 02138 Harvard Stem Cell Institute, Howard Hughes Medical Institute, and Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA 02138

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http://dx.doi.org/10.1084/jem.20141528DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4419349PMC
May 2015

Flow-induced protein kinase A-CREB pathway acts via BMP signaling to promote HSC emergence.

J Exp Med 2015 May 13;212(5):633-48. Epub 2015 Apr 13.

Division of Pediatric Hematology/Oncology, Boston Children's Hospital and Dana Farber Cancer Institute; Howard Hughes Medical Institute, Harvard Stem Cell Institute; Stem Cell Transplantation Program, Division of Pediatric Hematology/Oncology, Boston Children's Hospital and Dana Farber Cancer Institute; and Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115 Division of Pediatric Hematology/Oncology, Boston Children's Hospital and Dana Farber Cancer Institute; Howard Hughes Medical Institute, Harvard Stem Cell Institute; Stem Cell Transplantation Program, Division of Pediatric Hematology/Oncology, Boston Children's Hospital and Dana Farber Cancer Institute; and Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115 Division of Pediatric Hematology/Oncology, Boston Children's Hospital and Dana Farber Cancer Institute; Howard Hughes Medical Institute, Harvard Stem Cell Institute; Stem Cell Transplantation Program, Division of Pediatric Hematology/Oncology, Boston Children's Hospital and Dana Farber Cancer Institute; and Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115

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http://www.jem.org/lookup/doi/10.1084/jem.20141514
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http://dx.doi.org/10.1084/jem.20141514DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4419355PMC
May 2015

A CRISPR/Cas9 vector system for tissue-specific gene disruption in zebrafish.

Dev Cell 2015 Mar 5;32(6):756-64. Epub 2015 Mar 5.

Stem Cell Program and Division of Hematology/Oncology, Boston Children's Hospital and Dana Farber Cancer Institute, Boston, MA 02115, USA; Harvard Stem Cell Institute, Harvard University, Cambridge, MA 02138, USA; Howard Hughes Medical Institute, Boston, MA 02115, USA. Electronic address:

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http://dx.doi.org/10.1016/j.devcel.2015.01.032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4379706PMC
March 2015

Notch1 acts via Foxc2 to promote definitive hematopoiesis via effects on hemogenic endothelium.

Blood 2015 Feb 13;125(9):1418-26. Epub 2015 Jan 13.

Stem Cell Program and Division of Hematology/Oncology, Children's Hospital Boston and Dana-Farber Cancer Institute, Howard Hughes Medical Institute, Harvard Medical School, Boston, MA; Stem Cell Transplantation Program, Manton Center for Orphan Disease Research, Children's Hospital Boston, Boston, MA; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA; Harvard Stem Cell Institute, Boston, MA;

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http://dx.doi.org/10.1182/blood-2014-04-568170DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4342355PMC
February 2015

DNA methyltransferase 1 functions through C/ebpa to maintain hematopoietic stem and progenitor cells in zebrafish.

J Hematol Oncol 2015 Feb 22;8:15. Epub 2015 Feb 22.

CNRS-LIA124, Sino-French Research Center for Life Sciences and Genomics, State Key Laboratory of Medical Genomics, Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China.

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http://www.jhoonline.org/content/8/1/15
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http://dx.doi.org/10.1186/s13045-015-0115-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372312PMC
February 2015

A comparison of non-integrating reprogramming methods.

Nat Biotechnol 2015 Jan 1;33(1):58-63. Epub 2014 Dec 1.

1] Division of Pediatric Hematology/Oncology, Boston Children's Hospital, Dana-Farber Cancer Institute, Boston, Massachusetts, USA. [2] Harvard Stem Cell Institute, Cambridge, Massachusetts, USA. [3] Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts, USA. [4] Howard Hughes Medical Institute, Children's Hospital Boston and Dana Farber Cancer Institute, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1038/nbt.3070DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4329913PMC
January 2015

Hematopoietic stem cell arrival triggers dynamic remodeling of the perivascular niche.

Cell 2015 Jan;160(1-2):241-52

Stem Cell Program and Division of Hematology/Oncology, Boston Children's Hospital and Dana Farber Cancer Institute, Howard Hughes Medical Institute, Harvard Stem Cell Institute, Harvard Medical School, Boston, MA 02115, USA; Biological and Biomedical Sciences, Harvard University, Cambridge, MA 02138, USA; Chemical Biology Program, Harvard University, Cambridge, MA 02138, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2014.12.032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4346256PMC
January 2015

Getting more for your marrow: boosting hematopoietic stem cell numbers with PGE2.

Exp Cell Res 2014 Dec 2;329(2):220-6. Epub 2014 Aug 2.

Stem Cell Program and Division of Hematology/Oncology, Boston Children׳s Hospital and Dana Farber Cancer Institute, Howard Hughes Medical Institute, Harvard Stem Cell Institute, and Harvard Medical School, Boston, MA 02115, USA. Electronic address:

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http://dx.doi.org/10.1016/j.yexcr.2014.07.030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4250398PMC
December 2014

Intrinsic expression of a multiexon type 3 deiodinase gene controls zebrafish embryo size.

Endocrinology 2014 Oct 8;155(10):4069-80. Epub 2014 Jul 8.

State Key Laboratory of Medical Genomics (C.G., X.C., H.S.), Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200025 China; Thyroid Program of the Division of Endocrinology (C.G., X.C., H.S., M.A.M., R.H.J., N.Y.L., L.A.C., S.A.H.) and Clinical Research Center (H.A.F.), Boston Children's Hospital; Stem Cell Program and Division of Hematology/Oncology (Y.Z., J.J.G., D.W., L.I.Z.), Boston Children's Hospital, Harvard Stem Cell Institute, Harvard Medical School, and Howard Hughes Medical Institute; Department of Medicine (A.V.L., V.N.G., S.A.H.), Brigham and Women's Hospital; Dana Farber Cancer Institute (V.N.G., L.I.Z., S.A.H.), Boston, Massachusetts 02115; and Departments of Physiology and Pharmacology (T.S.S.), Oregon Health and Science University, Portland, Oregon 97239.

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http://dx.doi.org/10.1210/en.2013-2029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4164935PMC
October 2014

Selective microRNA uridylation by Zcchc6 (TUT7) and Zcchc11 (TUT4).

Nucleic Acids Res 2014 Oct 15;42(18):11777-91. Epub 2014 Sep 15.

Stem Cell Program, Boston Children's Hospital, Boston, MA 02115, USA Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA Department of Pediatrics, Harvard Medical School, Boston, MA 02115, USA Harvard Stem Cell Institute, Cambridge, MA 02138, USA

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http://academic.oup.com/nar/article/42/18/11777/2435142/Sele
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http://dx.doi.org/10.1093/nar/gku805DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4191393PMC
October 2014

Dissection of vertebrate hematopoiesis using zebrafish thrombopoietin.

Blood 2014 Jul 28;124(2):220-8. Epub 2014 May 28.

Department of Cell Differentiation, Institute of Molecular Genetics, Academy of Sciences of the Czech Republic v.v.i., Prague, Czech Republic;

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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2014-03-56
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http://dx.doi.org/10.1182/blood-2014-03-564682DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4093681PMC
July 2014

Small molecule screening in zebrafish: swimming in potential drug therapies.

Wiley Interdiscip Rev Dev Biol 2012 May-Jun;1(3):459-68. Epub 2012 Feb 28.

Stem Cell Program and Hematology/Oncology, Children's Hospital Boston, Howard Hughes Medical Institute, Harvard Stem Cell Institute, Harvard Medical School, Boston, MA, USA.

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http://doi.wiley.com/10.1002/wdev.37
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April 2014

Mutations in QARS, encoding glutaminyl-tRNA synthetase, cause progressive microcephaly, cerebral-cerebellar atrophy, and intractable seizures.

Am J Hum Genet 2014 Apr 20;94(4):547-58. Epub 2014 Mar 20.

Department of Pediatric Neurology, Centre de Reference Epilepsies Rares, Hôpital Necker-Enfants Malades, Assistance Publique-Hôpitaux de Paris, 75015 Paris, France; Institut National de la Santé et de la Recherche Médicale U1129, Université Paris Descartes, 75006 Paris, France; Institut National de la Santé et de la Recherche Médicale U1129, NeuroSpin, Commissariat à l'Énergie Atomique et aux Énergies Alternatives, 91191 Gif-sur-Yvette, France. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00029297140010
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http://dx.doi.org/10.1016/j.ajhg.2014.03.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3980424PMC
April 2014

Neural crest development and craniofacial morphogenesis is coordinated by nitric oxide and histone acetylation.

Chem Biol 2014 Apr 27;21(4):488-501. Epub 2014 Mar 27.

Center for Regenerative Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA; Division of Plastic and Reconstructive Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA; Shriners Hospitals for Children, Boston, MA 02114, USA; Harvard Stem Cell Institute, Boston, MA 02114, USA. Electronic address:

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http://dx.doi.org/10.1016/j.chembiol.2014.02.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4349424PMC
April 2014

Unexpectedly uneven: posttransplant skeletal distribution of hematopoietic stem cell clones.

J Exp Med 2014 Mar;211(3):384-5

Boston Children's Hospital, Harvard Medical School, Howard Hughes Medical Institute.

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http://www.jem.org/lookup/doi/10.1084/jem.2113insight2
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http://dx.doi.org/10.1084/jem.2113insight2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3949574PMC
March 2014

The histone methyltransferase SUV39H1 suppresses embryonal rhabdomyosarcoma formation in zebrafish.

PLoS One 2013 21;8(5):e64969. Epub 2013 May 21.

Stem Cell Program and Division of Hematology/Oncology, Boston Children's Hospital and Dana Farber Cancer Institute, Howard Hughes Medical Institute, Harvard Stem Cell Institute, Harvard Medical School, Boston, Massachusetts, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0064969PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3660348PMC
December 2013

Assaying hematopoiesis using zebrafish.

Blood Cells Mol Dis 2013 Dec 2;51(4):271-6. Epub 2013 Aug 2.

Stem Cell Program and Division of Hematology/Oncology, Children's Hospital Boston, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1016/j.bcmd.2013.07.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3882012PMC
December 2013

The zebrafish granulocyte colony-stimulating factors (Gcsfs): 2 paralogous cytokines and their roles in hematopoietic development and maintenance.

Blood 2013 Dec 15;122(24):3918-28. Epub 2013 Oct 15.

Department of Cellular and Molecular Medicine, University of California at San Diego School of Medicine, La Jolla, CA;

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http://dx.doi.org/10.1182/blood-2012-12-475392DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3854111PMC
December 2013

zebraflash transgenic lines for in vivo bioluminescence imaging of stem cells and regeneration in adult zebrafish.

Development 2013 Dec 6;140(24):4988-97. Epub 2013 Nov 6.

Department of Cell Biology and Howard Hughes Medical Institute, Duke University Medical Center, Durham, NC 27710, USA.

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http://dev.biologists.org/cgi/doi/10.1242/dev.102053
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http://dx.doi.org/10.1242/dev.102053DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3848191PMC
December 2013

A network of epigenetic regulators guides developmental haematopoiesis in vivo.

Nat Cell Biol 2013 Dec 17;15(12):1516-25. Epub 2013 Nov 17.

1] Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA [2] Stem Cell Program and Division of Pediatric Hematology/Oncology, Children's Hospital Boston and Dana-Farber Cancer Institute, Howard Hughes Medical Institute, Boston, Massachusetts 02115, USA [3].

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http://dx.doi.org/10.1038/ncb2870DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3959952PMC
December 2013

Of fish and men: using zebrafish to fight human diseases.

Trends Cell Biol 2013 Dec;23(12):584-6

Stem Cell Program and Division of Hematology/Oncology, Children's Hospital and Dana Farber Cancer Institute, Boston, MA, USA.

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http://dx.doi.org/10.1016/j.tcb.2013.09.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6047759PMC
December 2013

Induction of multipotential hematopoietic progenitors from human pluripotent stem cells via respecification of lineage-restricted precursors.

Cell Stem Cell 2013 Oct;13(4):459-70

Stem Cell Transplantation Program, Division of Pediatric Hematology/Oncology, Manton Center for Orphan Disease Research, Howard Hughes Medical Institute, Children's Hospital Boston and Dana Farber Cancer Institute; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA; Harvard Stem Cell Institute, Cambridge, MA 02138, USA.

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http://dx.doi.org/10.1016/j.stem.2013.09.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3888026PMC
October 2013

Zebrafish rhabdomyosarcoma reflects the developmental stage of oncogene expression during myogenesis.

Development 2013 Jul;140(14):3040-50

Stem Cell Program and Division of Hematology/Oncology, Boston Children's Hospital and Dana-Farber Cancer Institute, Boston, MA 02115, USA.

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http://dx.doi.org/10.1242/dev.087858DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3699286PMC
July 2013

A novel chemical screening strategy in zebrafish identifies common pathways in embryogenesis and rhabdomyosarcoma development.

Development 2013 Jun 24;140(11):2354-64. Epub 2013 Apr 24.

Stem Cell Program and Division of Hematology/Oncology, Children's Hospital and Dana Farber Cancer Institute, Howard Hughes Medical Institute, Harvard Stem Cell Institute, Harvard Medical School, Boston, MA 02115, USA.

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http://dev.biologists.org/cgi/doi/10.1242/dev.088427
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http://dx.doi.org/10.1242/dev.088427DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3653557PMC
June 2013

Hematopoiesis.

Development 2013 Jun;140(12):2463-7

HHMI/Children's Hospital Boston, Boston, MA 02115, USA.

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http://dx.doi.org/10.1242/dev.083147DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3666375PMC
June 2013

The zebrafish reference genome sequence and its relationship to the human genome.

Authors:
Kerstin Howe Matthew D Clark Carlos F Torroja James Torrance Camille Berthelot Matthieu Muffato John E Collins Sean Humphray Karen McLaren Lucy Matthews Stuart McLaren Ian Sealy Mario Caccamo Carol Churcher Carol Scott Jeffrey C Barrett Romke Koch Gerd-Jörg Rauch Simon White William Chow Britt Kilian Leonor T Quintais José A Guerra-Assunção Yi Zhou Yong Gu Jennifer Yen Jan-Hinnerk Vogel Tina Eyre Seth Redmond Ruby Banerjee Jianxiang Chi Beiyuan Fu Elizabeth Langley Sean F Maguire Gavin K Laird David Lloyd Emma Kenyon Sarah Donaldson Harminder Sehra Jeff Almeida-King Jane Loveland Stephen Trevanion Matt Jones Mike Quail Dave Willey Adrienne Hunt John Burton Sarah Sims Kirsten McLay Bob Plumb Joy Davis Chris Clee Karen Oliver Richard Clark Clare Riddle David Elliot David Eliott Glen Threadgold Glenn Harden Darren Ware Sharmin Begum Beverley Mortimore Beverly Mortimer Giselle Kerry Paul Heath Benjamin Phillimore Alan Tracey Nicole Corby Matthew Dunn Christopher Johnson Jonathan Wood Susan Clark Sarah Pelan Guy Griffiths Michelle Smith Rebecca Glithero Philip Howden Nicholas Barker Christine Lloyd Christopher Stevens Joanna Harley Karen Holt Georgios Panagiotidis Jamieson Lovell Helen Beasley Carl Henderson Daria Gordon Katherine Auger Deborah Wright Joanna Collins Claire Raisen Lauren Dyer Kenric Leung Lauren Robertson Kirsty Ambridge Daniel Leongamornlert Sarah McGuire Ruth Gilderthorp Coline Griffiths Deepa Manthravadi Sarah Nichol Gary Barker Siobhan Whitehead Michael Kay Jacqueline Brown Clare Murnane Emma Gray Matthew Humphries Neil Sycamore Darren Barker David Saunders Justene Wallis Anne Babbage Sian Hammond Maryam Mashreghi-Mohammadi Lucy Barr Sancha Martin Paul Wray Andrew Ellington Nicholas Matthews Matthew Ellwood Rebecca Woodmansey Graham Clark James D Cooper James Cooper Anthony Tromans Darren Grafham Carl Skuce Richard Pandian Robert Andrews Elliot Harrison Andrew Kimberley Jane Garnett Nigel Fosker Rebekah Hall Patrick Garner Daniel Kelly Christine Bird Sophie Palmer Ines Gehring Andrea Berger Christopher M Dooley Zübeyde Ersan-Ürün Cigdem Eser Horst Geiger Maria Geisler Lena Karotki Anette Kirn Judith Konantz Martina Konantz Martina Oberländer Silke Rudolph-Geiger Mathias Teucke Christa Lanz Günter Raddatz Kazutoyo Osoegawa Baoli Zhu Amanda Rapp Sara Widaa Cordelia Langford Fengtang Yang Stephan C Schuster Nigel P Carter Jennifer Harrow Zemin Ning Javier Herrero Steve M J Searle Anton Enright Robert Geisler Ronald H A Plasterk Charles Lee Monte Westerfield Pieter J de Jong Leonard I Zon John H Postlethwait Christiane Nüsslein-Volhard Tim J P Hubbard Hugues Roest Crollius Jane Rogers Derek L Stemple

Nature 2013 Apr 17;496(7446):498-503. Epub 2013 Apr 17.

Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK.

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http://dx.doi.org/10.1038/nature12111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3703927PMC
April 2013