Publications by authors named "Leonard D Shultz"

100Publications

Understanding Normal and Malignant Human Hematopoiesis Using Next-Generation Humanized Mice.

Trends Immunol 2020 08 3;41(8):706-720. Epub 2020 Jul 3.

RIKEN Center for Integrative Medical Sciences, Yokohama City, Kanagawa, 230-0045, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.it.2020.06.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7395895PMC
August 2020

Dapagliflozin Does Not Directly Affect Human α or β Cells.

Endocrinology 2020 Aug;161(8)

Division of Diabetes, Endocrinology and Metabolism, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee.

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http://dx.doi.org/10.1210/endocr/bqaa080DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7375801PMC
August 2020

Improved mouse models and advanced genetic and genomic technologies for the study of neutrophils.

Drug Discov Today 2020 Jun 5;25(6):1013-1025. Epub 2020 May 5.

The Jackson Laboratory for Mammalian Genetics, 600 Main Street, Bar Harbor, ME 04609 USA.

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http://dx.doi.org/10.1016/j.drudis.2020.03.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7329609PMC
June 2020

Genome-wide Analysis of Salmonella enterica serovar Typhi in Humanized Mice Reveals Key Virulence Features.

Cell Host Microbe 2019 09 22;26(3):426-434.e6. Epub 2019 Aug 22.

Department of Microbiology, University of Washington, Seattle, WA 98195, USA; Department of Global Health, University of Washington, Seattle, WA 98195, USA; Department of Laboratory Medicine, University of Washington, Seattle, WA 98195, USA. Electronic address:

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http://dx.doi.org/10.1016/j.chom.2019.08.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6742556PMC
September 2019

Humanized immune system mouse models: progress, challenges and opportunities.

Nat Immunol 2019 07;20(7):770-774

Division of Allergy, Immunology and Transplantation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD, USA.

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http://dx.doi.org/10.1038/s41590-019-0416-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265413PMC
July 2019

Mesenchymal stem cells: From regeneration to cancer.

Pharmacol Ther 2019 08 16;200:42-54. Epub 2019 Apr 16.

The Jackson Laboratory, Bar Harbor, ME 04609, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01637258193006
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http://dx.doi.org/10.1016/j.pharmthera.2019.04.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6626571PMC
August 2019

Humanized mouse models of immunological diseases and precision medicine.

Mamm Genome 2019 06 7;30(5-6):123-142. Epub 2019 Mar 7.

Diabetes Center of Excellence, The University of Massachusetts Medical School, 368 Plantation Street, Worcester, MA, 01605, USA.

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http://link.springer.com/10.1007/s00335-019-09796-2
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http://dx.doi.org/10.1007/s00335-019-09796-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6610695PMC
June 2019

Ectopic high endothelial venules in pancreatic ductal adenocarcinoma: A unique site for targeted delivery.

EBioMedicine 2018 Dec 27;38:79-88. Epub 2018 Nov 27.

Transplantation Research Center, Renal Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2018.11.030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306381PMC
December 2018

Ectonucleoside Triphosphate Diphosphohydrolase-3 Antibody Targets Adult Human Pancreatic β Cells for In Vitro and In Vivo Analysis.

Cell Metab 2019 03 15;29(3):745-754.e4. Epub 2018 Nov 15.

Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN 37240, USA; Department of Medicine, Division of Diabetes, Endocrinology, and Metabolism, Vanderbilt University Medical Center, Nashville, TN 37232, USA; VA Tennessee Valley Healthcare, Nashville, TN 37212, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15504131183063
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http://dx.doi.org/10.1016/j.cmet.2018.10.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6402969PMC
March 2019

Genetic Models of Macrophage Depletion.

Methods Mol Biol 2018 ;1784:243-258

The Jackson Laboratory, Bar Harbor, ME, USA.

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http://dx.doi.org/10.1007/978-1-4939-7837-3_22DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333569PMC
January 2019

α Cell Function and Gene Expression Are Compromised in Type 1 Diabetes.

Cell Rep 2018 03;22(10):2667-2676

Department of Medicine, Division of Diabetes, Endocrinology and Metabolism, Vanderbilt University Medical Center, Nashville, TN, USA; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, USA; Department of Veterans Affairs, Tennessee Valley Healthcare System, Nashville, TN, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2018.02.032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368357PMC
March 2018

Tissue-specific role of RHBDF2 in cutaneous wound healing and hyperproliferative skin disease.

BMC Res Notes 2017 Nov 7;10(1):573. Epub 2017 Nov 7.

The Jackson Laboratory, 600 Main Street, Bar Harbor, ME, 04609, USA.

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http://dx.doi.org/10.1186/s13104-017-2899-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5678570PMC
November 2017

Survival Advantage of Both Human Hepatocyte Xenografts and Genome-Edited Hepatocytes for Treatment of α-1 Antitrypsin Deficiency.

Mol Ther 2017 11 25;25(11):2477-2489. Epub 2017 Sep 25.

Department of Pediatrics and Horae Gene Therapy Center, University of Massachusetts Medical School, Worcester, MA 01605, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ymthe.2017.09.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5675605PMC
November 2017

Age-dependent human β cell proliferation induced by glucagon-like peptide 1 and calcineurin signaling.

J Clin Invest 2017 Oct 18;127(10):3835-3844. Epub 2017 Sep 18.

Division of Diabetes, Endocrinology and Metabolism, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.

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http://dx.doi.org/10.1172/JCI91761DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617654PMC
October 2017

Alloimmune Responses of Humanized Mice to Human Pluripotent Stem Cell Therapeutics.

Cell Rep 2017 Aug;20(8):1978-1990

Stanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, California, USA; Department of Medicine, Stanford University School of Medicine, Stanford, California, USA; Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, California, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2017.08.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5573767PMC
August 2017

mRNA-mediated glycoengineering ameliorates deficient homing of human stem cell-derived hematopoietic progenitors.

J Clin Invest 2017 Jun 8;127(6):2433-2437. Epub 2017 May 8.

Program in Cellular and Molecular Medicine, Division of Hematology/Oncology, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1172/JCI92030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5451245PMC
June 2017

Development of Humanized Mice in the Age of Genome Editing.

J Cell Biochem 2017 10 15;118(10):3043-3048. Epub 2017 May 15.

The Jackson Laboratory, Bar Harbor 04609, Maine.

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http://doi.wiley.com/10.1002/jcb.26002
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http://dx.doi.org/10.1002/jcb.26002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5550330PMC
October 2017

Early induction of NRF2 antioxidant pathway by RHBDF2 mediates rapid cutaneous wound healing.

Exp Mol Pathol 2017 04 6;102(2):337-346. Epub 2017 Mar 6.

The Jackson Laboratory, Bar Harbor, ME 04609, United States. Electronic address:

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http://dx.doi.org/10.1016/j.yexmp.2017.03.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436942PMC
April 2017

Analysis of parameters that affect human hematopoietic cell outputs in mutant c-kit-immunodeficient mice.

Exp Hematol 2017 04 11;48:41-49. Epub 2017 Jan 11.

Terry Fox Laboratory, British Columbia Cancer Agency, Vancouver, BC, Canada; Department of Medicine, University of British Columbia, Vancouver, BC, Canada; Department of Medical Genetics, University of British Columbia, Vancouver, BC, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.exphem.2016.12.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926796PMC
April 2017

Improved B cell development in humanized NOD mice transgenically expressing human stem cell factor, granulocyte-macrophage colony-stimulating factor and interleukin-3.

Immun Inflamm Dis 2016 12 28;4(4):427-440. Epub 2016 Aug 28.

Program in Molecular Medicine, Diabetes Center of Excellence™ University of Massachusetts Medical School Worcester Massachusetts 01605 USA.

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http://doi.wiley.com/10.1002/iid3.124
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http://dx.doi.org/10.1002/iid3.124DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5134721PMC
December 2016

Humanized Mouse Models of Clinical Disease.

Annu Rev Pathol 2017 Jan 5;12:187-215. Epub 2016 Dec 5.

The Jackson Laboratory, Bar Harbor, Maine 04609; email:

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http://dx.doi.org/10.1146/annurev-pathol-052016-100332DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5280554PMC
January 2017

Distinct Differences on Neointima Formation in Immunodeficient and Humanized Mice after Carotid or Femoral Arterial Injury.

Sci Rep 2016 10 19;6:35387. Epub 2016 Oct 19.

Department of Pathology and Medical Biology-Pathology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.

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http://www.nature.com/articles/srep35387
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http://dx.doi.org/10.1038/srep35387DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5069488PMC
October 2016

Cell-Extrinsic MHC Class I Molecule Engagement Augments Human NK Cell Education Programmed by Cell-Intrinsic MHC Class I.

Immunity 2016 08 2;45(2):280-91. Epub 2016 Aug 2.

Immunology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Weill Cornell Medical College, New York, NY 10065, USA. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2016.07.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5003427PMC
August 2016

Generation of Immunodeficient Mice Bearing Human Immune Systems by the Engraftment of Hematopoietic Stem Cells.

Methods Mol Biol 2016 ;1438:67-78

Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, MA, 01605, USA.

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http://dx.doi.org/10.1007/978-1-4939-3661-8_4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5268072PMC
December 2017

Humanized mouse model of mast cell-mediated passive cutaneous anaphylaxis and passive systemic anaphylaxis.

J Allergy Clin Immunol 2016 09 6;138(3):769-779. Epub 2016 Apr 6.

Diabetes Center of Excellence, Department of Molecular Medicine, University of Massachusetts Medical School, Worcester, Mass. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2016.01.049DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5014665PMC
September 2016

Patient-Derived Tumor Xenografts: Why Now?

JAMA Oncol 2016 May;2(5):567-568

The Jackson Laboratory, Bar Harbor, Maine.

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http://dx.doi.org/10.1001/jamaoncol.2016.0193DOI Listing
May 2016

P-Rex1 Promotes Resistance to VEGF/VEGFR-Targeted Therapy in Prostate Cancer.

Cell Rep 2016 Mar 25;14(9):2193-2208. Epub 2016 Feb 25.

Department of Molecular, Cell and Cancer Biology, University of Massachusetts Medical School, Worcester, MA 01605, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2016.02.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791963PMC
March 2016

Genetic ablation of lymphocytes and cytokine signaling in nonobese diabetic mice prevents diet-induced obesity and insulin resistance.

FASEB J 2016 Mar 7;30(3):1328-38. Epub 2015 Dec 7.

*Program in Molecular Medicine, Diabetes Center of Excellence, and Division of Endocrinology, Metabolism, and Diabetes, Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, USA; The Jackson Laboratory, Bar Harbor, Maine, USA; and World Class University Biomodulation Major, Department of Agricultural Biotechnology and Center for Food and Bioconvergence, Seoul National University, Seoul, Republic of Korea

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http://dx.doi.org/10.1096/fj.15-280610DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4750424PMC
March 2016

Convergent mutations and kinase fusions lead to oncogenic STAT3 activation in anaplastic large cell lymphoma.

Cancer Cell 2015 Apr;27(4):516-32

Department of Molecular Biotechnology and Health Science and Center for Experimental Research and Medical Studies, University of Torino, 10126 Torino, Italy; Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, NY 10021, USA; Department of Pathology and NYU Cancer Center, New York University School of Medicine, New York, NY 10016, USA. Electronic address:

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http://www.cell.com/cancer-cell/pdf/S1535-6108(15)00094-X.pd
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http://linkinghub.elsevier.com/retrieve/pii/S153561081500094
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http://dx.doi.org/10.1016/j.ccell.2015.03.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5898430PMC
April 2015

MEK guards proteome stability and inhibits tumor-suppressive amyloidogenesis via HSF1.

Cell 2015 Feb;160(4):729-744

The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2015.01.028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4564124PMC
February 2015

Viral infection of engrafted human islets leads to diabetes.

Diabetes 2015 Apr 12;64(4):1358-69. Epub 2014 Nov 12.

Department of Medicine, University of Massachusetts Medical School, Worcester, MA

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http://dx.doi.org/10.2337/db14-1020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4375078PMC
April 2015

Dengue virus infection induces broadly cross-reactive human IgM antibodies that recognize intact virions in humanized BLT-NSG mice.

Exp Biol Med (Maywood) 2015 Jan 14;240(1):67-78. Epub 2014 Aug 14.

Division of Infectious Diseases and Immunology, University of Massachusetts Medical School, Worcester, MA 01655, USA

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http://dx.doi.org/10.1177/1535370214546273DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4446989PMC
January 2015

Immunodeficient mouse model for human hematopoietic stem cell engraftment and immune system development.

Methods Mol Biol 2014 ;1185:267-78

Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, MA, USA.

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http://dx.doi.org/10.1007/978-1-4939-1133-2_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4476265PMC
March 2015

Inhibition of bromodomain proteins for the treatment of human diffuse large B-cell lymphoma.

Clin Cancer Res 2015 Jan 9;21(1):113-22. Epub 2014 Jul 9.

Department of Cell and Developmental Biology, University of Massachusetts Medical School, Worcester, Massachusetts.

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http://dx.doi.org/10.1158/1078-0432.CCR-13-3346DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4286476PMC
January 2015

Human cancer growth and therapy in immunodeficient mouse models.

Cold Spring Harb Protoc 2014 Jul 1;2014(7):694-708. Epub 2014 Jul 1.

University of Massachusetts Medical School, Worcester, Massachusetts 01605.

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http://dx.doi.org/10.1101/pdb.top073585DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4411952PMC
July 2014

Subcapsular transplantation of tissue in the kidney.

Cold Spring Harb Protoc 2014 Jul 1;2014(7):737-40. Epub 2014 Jul 1.

University of Massachusetts Medical School, Worcester, Massachusetts 01605.

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http://dx.doi.org/10.1101/pdb.prot078089DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4411958PMC
July 2014

NOD-scidIl2rg (tm1Wjl) and NOD-Rag1 (null) Il2rg (tm1Wjl) : a model for stromal cell-tumor cell interaction for human colon cancer.

Dig Dis Sci 2014 Jun 6;59(6):1169-79. Epub 2014 May 6.

Division of Colorectal Surgery, Department of Surgery, UMass Memorial Health Care System, Worcester, MA, USA.

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http://link.springer.com/10.1007/s10620-014-3168-5
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http://dx.doi.org/10.1007/s10620-014-3168-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4032472PMC
June 2014

Regulated splicing of the α6 integrin cytoplasmic domain determines the fate of breast cancer stem cells.

Cell Rep 2014 May 24;7(3):747-61. Epub 2014 Apr 24.

Department of Cancer Biology, University of Massachusetts Medical School, Worcester, MA 01605, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2014.03.059DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038359PMC
May 2014

Generation of improved humanized mouse models for human infectious diseases.

J Immunol Methods 2014 Aug 4;410:3-17. Epub 2014 Mar 4.

The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, United States. Electronic address:

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http://dx.doi.org/10.1016/j.jim.2014.02.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4155027PMC
August 2014

An epigenetic mechanism of resistance to targeted therapy in T cell acute lymphoblastic leukemia.

Nat Genet 2014 Apr 2;46(4):364-70. Epub 2014 Mar 2.

1] Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA. [2] Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA. [3] Center for Cancer Research, Massachusetts General Hospital, Boston, Massachusetts, USA. [4] Howard Hughes Medical Institute, Chevy Chase, Maryland, USA.

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http://www.nature.com/articles/ng.2913
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http://dx.doi.org/10.1038/ng.2913DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4086945PMC
April 2014

Chronic proliferative dermatitis in Sharpin null mice: development of an autoinflammatory disease in the absence of B and T lymphocytes and IL4/IL13 signaling.

PLoS One 2014 21;9(1):e85666. Epub 2014 Jan 21.

The Jackson Laboratory, Bar Harbor, Maine, United States of America ; Department of Comparative Pathobiology, College of Veterinary Medicine, Purdue University, West Lafayette, Indiana, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0085666PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3897490PMC
October 2014

Site-specific Genome Editing in PBMCs With PLGA Nanoparticle-delivered PNAs Confers HIV-1 Resistance in Humanized Mice.

Mol Ther Nucleic Acids 2013 Nov 19;2:e135. Epub 2013 Nov 19.

Department of Therapeutic Radiology and Genetics, Yale University School of Medicine, New Haven, Connecticut, USA.

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http://dx.doi.org/10.1038/mtna.2013.59DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3889188PMC
November 2013

Overcoming current limitations in humanized mouse research.

J Infect Dis 2013 Nov;208 Suppl 2:S125-30

Program in Molecular Medicine, University of Massachusetts Medical School, Worcester.

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http://dx.doi.org/10.1093/infdis/jit319DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3807974PMC
November 2013

Changes in ovarian tumor cell number, tumor vasculature, and T cell function monitored in vivo using a novel xenograft model.

Cancer Immun 2013 31;13:11. Epub 2013 May 31.

Department of Microbiology and Immunology, School of Medicine and Biomedical Sciences, The State University of New York at Buffalo, Buffalo, NY, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3721261PMC
May 2014

Humanized mice for the study of infectious diseases.

Curr Opin Immunol 2013 Aug 8;25(4):428-35. Epub 2013 Jun 8.

Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, MA 01655, United States.

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http://dx.doi.org/10.1016/j.coi.2013.05.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3775881PMC
August 2013

Generation of islet-like cells from mouse gall bladder by direct ex vivo reprogramming.

Stem Cell Res 2013 Jul 18;11(1):503-15. Epub 2013 Feb 18.

Oregon Stem Cell Center, Papé Family Pediatric Research Institute, Oregon Health & Science University, Portland, OR 97203, USA.

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http://dx.doi.org/10.1016/j.scr.2013.02.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3940065PMC
July 2013

Inflammatory dilated cardiomyopathy in Abcg5-deficient mice.

Toxicol Pathol 2013 Aug 5;41(6):880-92. Epub 2012 Nov 5.

Department of Pathology Microbiology and Immunology, School of Veterinary Medicine, University of California-Davis, CA 95616, USA.

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http://dx.doi.org/10.1177/0192623312466191DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3905339PMC
August 2013

Humanized mice for immune system investigation: progress, promise and challenges.

Nat Rev Immunol 2012 Nov 12;12(11):786-98. Epub 2012 Oct 12.

Jackson Laboratory, 600 Main Street, Bar Harbor, Maine 04609, USA.

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http://dx.doi.org/10.1038/nri3311DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3749872PMC
November 2012

A novel animal model for bone metastasis in human lung cancer.

Oncol Lett 2012 Apr 1;3(4):802-806. Epub 2012 Feb 1.

Laboratory of Endocrinology and Metabolism, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P.R. China.

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http://dx.doi.org/10.3892/ol.2012.586DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3362336PMC
April 2012

Development of mature and functional human myeloid subsets in hematopoietic stem cell-engrafted NOD/SCID/IL2rγKO mice.

J Immunol 2012 Jun 18;188(12):6145-55. Epub 2012 May 18.

Department of Medical Genome Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Chiba, Japan.

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http://dx.doi.org/10.4049/jimmunol.1103660DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3370073PMC
June 2012