Leonard B Saltz

Leonard B Saltz

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Leonard B Saltz

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Molecular and cytogenetic characteristics of myeloid malignancies following luminal gastrointestinal cancer.

Leuk Res 2019 Jul 24;82:19-23. Epub 2019 May 24.

Department of Medicine, Memorial Sloan Kettering Cancer Center, USA; Division of Hematologic Malignancies, Leukemia Service, Memorial Sloan Kettering Cancer Center, 1275 York Ave, New York, NY, 10065, USA; Department of Medicine, Weill Cornell Medical College, 1300 York Ave, New York, NY, 10065, USA. Electronic address:

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http://dx.doi.org/10.1016/j.leukres.2019.05.010DOI Listing
July 2019

Prognostic association of PTGS2 (COX-2) over-expression according to BRAF mutation status in colorectal cancer: Results from two prospective cohorts and CALGB 89803 (Alliance) trial.

Eur J Cancer 2019 Apr 1;111:82-93. Epub 2019 Mar 1.

Department of Oncologic Pathology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA, USA; Program in MPE Molecular Pathological Epidemiology, Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA; Broad Institute of MIT and Harvard, Cambridge, MA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2019.01.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6436990PMC
April 2019

Precision oncology giveth and precision oncology taketh away.

Authors:
Leonard B Saltz

Lancet Oncol 2019 Apr 8;20(4):464-466. Epub 2019 Mar 8.

Gastrointestinal Oncology Service, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Weill Cornell Medical College, New York, NY, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S14702045193009
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http://dx.doi.org/10.1016/S1470-2045(19)30095-6DOI Listing
April 2019

Value-Added Decisions in Oncology.

Am Soc Clin Oncol Educ Book 2019 Jan 17;39:122-131. Epub 2019 May 17.

3 Gastrointestinal Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.

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http://dx.doi.org/10.1200/EDBK_238831DOI Listing
January 2019

The Addition of Bevacizumab to Oxaliplatin-Based Chemotherapy: Impact Upon Hepatic Sinusoidal Injury and Thrombocytopenia.

J Natl Cancer Inst 2018 08;110(8):888-894

Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX.

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http://dx.doi.org/10.1093/jnci/djx288DOI Listing
August 2018

Can We Afford That CAR? Confronting the Effect of Novel Immunotherapies on Future Health Care Costs.

J Clin Oncol 2018 05 16;36(13):1381-1382. Epub 2018 Mar 16.

Angela K. Green and Leonard B. Saltz, Memorial Sloan Kettering Cancer Center, New York, NY.

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http://dx.doi.org/10.1200/JCO.2018.78.4397DOI Listing
May 2018

Assessing the Value of Next-Generation Sequencing Tests in a Dynamic Environment.

Am Soc Clin Oncol Educ Book 2018 May;38:139-146

From Sarah Cannon, Nashville, TN; Memorial Sloan Kettering Cancer Center, New York, NY; Hartford HealthCare Cancer Institute, Hartford, CT, Memorial Sloan Kettering Cancer Center, New York, NY.

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http://dx.doi.org/10.1200/EDBK_200825DOI Listing
May 2018

Nut Consumption and Survival in Patients With Stage III Colon Cancer: Results From CALGB 89803 (Alliance).

J Clin Oncol 2018 04 28;36(11):1112-1120. Epub 2018 Feb 28.

Temidayo Fadelu, Sui Zhang, Robert J. Mayer, Shuji Ogino, Kimmie Ng, Jeffrey Meyerhardt, and Charles S. Fuchs, Dana-Farber/Partners CancerCare; Shuji Ogino, Kana Wu, Walter Willett, and Edward Giovannucci, Harvard TH Chan School of Public Health; Shuji Ogino, Edward Giovannucci, and Ying Bao, Brigham and Women's Hospital, and Harvard Medical School, Boston, MA; Donna Niedzwiecki and Xing Ye, Alliance Statistics and Data Center, Duke University, Durham; Michael Messino, Southeast Clinical Oncology Research Consortium, Mission Hospitals, Asheville, NC; Leonard B. Saltz, Memorial Sloan Kettering Cancer Center, New York, NY; Rex B. Mowat, Toledo Community Hospital Oncology Program, Toledo, OH; Renaud Whittom, Hôpital du Sacré-Coeur de Montréal, Montreal, Quebec, Canada; Alexander Hantel, Loyola University Stritch School of Medicine, Naperville; Al B. Benson, Robert H Lurie Comprehensive Cancer Center, Northwestern University; Hedy L. Kindler, University of Chicago Comprehensive Cancer, Chicago, IL; Daniel M. Atienza, Virginia Oncology Associates, Norfolk, VA; Alan Venook, University of California at San Francisco Comprehensive Cancer Center, San Francisco, CA; and Charles S. Fuchs, Yale Cancer Center, Yale School of Medicine, New Haven, CT.

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http://dx.doi.org/10.1200/JCO.2017.75.5413DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5891130PMC
April 2018

Author's Response.

J Pain Symptom Manage 2018 01 13;55(1):e2-e3. Epub 2017 Nov 13.

Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA.

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http://dx.doi.org/10.1016/j.jpainsymman.2017.11.003DOI Listing
January 2018

How Should We Intervene on the Financial Toxicity of Cancer Care? One Shot, Four Perspectives.

Am Soc Clin Oncol Educ Book 2017 ;37:35-39

From the Duke Cancer Institute, Durham, NC; UnitedHealth Group, Minneapolis, MN; Pfizer, New York, NY; National Coalition for Cancer Survivorship, Washington, DC; Memorial Sloan Kettering Cancer Center; New York, NY.

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http://dx.doi.org/10.1200/EDBK_174893DOI Listing
December 2017

FDA Approval of Tisagenlecleucel: Promise and Complexities of a $475 000 Cancer Drug.

JAMA 2017 11;318(19):1861-1862

Memorial Sloan Kettering Cancer Center, New York, New York.

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http://dx.doi.org/10.1001/jama.2017.15218DOI Listing
November 2017

Raising the Dose and Raising the Cost: The Case of Pembrolizumab in Lung Cancer.

J Natl Cancer Inst 2017 11;109(11)

Center for Health Policy and Outcomes and Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.

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http://dx.doi.org/10.1093/jnci/djx125DOI Listing
November 2017

Complete Responses to Mitotane in Metastatic Adrenocortical Carcinoma-A New Look at an Old Drug.

Oncologist 2017 09 30;22(9):1102-1106. Epub 2017 May 30.

Department of Medicine, Center for Molecular Oncology, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.

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http://dx.doi.org/10.1634/theoncologist.2016-0459DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599197PMC
September 2017

Discharge to Subacute Rehabilitation Facilities Does Not Benefit Patients Hospitalized With Progressive Gastrointestinal Cancer.

J Pain Symptom Manage 2017 08 22;54(2):e4-e7. Epub 2017 Apr 22.

Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA.

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http://dx.doi.org/10.1016/j.jpainsymman.2017.03.006DOI Listing
August 2017

Capecitabine With Mitomycin Reduces Acute Hematologic Toxicity and Treatment Delays in Patients Undergoing Definitive Chemoradiation Using Intensity Modulated Radiation Therapy for Anal Cancer.

Int J Radiat Oncol Biol Phys 2017 08 22;98(5):1087-1095. Epub 2017 Mar 22.

Gastrointestinal Oncology Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York.

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http://dx.doi.org/10.1016/j.ijrobp.2017.03.022DOI Listing
August 2017

Erratum: Mutational landscape of metastatic cancer revealed from prospective clinical sequencing of 10,000 patients.

Authors:
Ahmet Zehir Ryma Benayed Ronak H Shah Aijazuddin Syed Sumit Middha Hyunjae R Kim Preethi Srinivasan Jianjiong Gao Debyani Chakravarty Sean M Devlin Matthew D Hellmann David A Barron Alison M Schram Meera Hameed Snjezana Dogan Dara S Ross Jaclyn F Hechtman Deborah F DeLair JinJuan Yao Diana L Mandelker Donavan T Cheng Raghu Chandramohan Abhinita S Mohanty Ryan N Ptashkin Gowtham Jayakumaran Meera Prasad Mustafa H Syed Anoop Balakrishnan Rema Zhen Y Liu Khedoudja Nafa Laetitia Borsu Justyna Sadowska Jacklyn Casanova Ruben Bacares Iwona J Kiecka Anna Razumova Julie B Son Lisa Stewart Tessara Baldi Kerry A Mullaney Hikmat Al-Ahmadie Efsevia Vakiani Adam A Abeshouse Alexander V Penson Philip Jonsson Niedzica Camacho Matthew T Chang Helen H Won Benjamin E Gross Ritika Kundra Zachary J Heins Hsiao-Wei Chen Sarah Phillips Hongxin Zhang Jiaojiao Wang Angelica Ochoa Jonathan Wills Michael Eubank Stacy B Thomas Stuart M Gardos Dalicia N Reales Jesse Galle Robert Durany Roy Cambria Wassim Abida Andrea Cercek Darren R Feldman Mrinal M Gounder A Ari Hakimi James J Harding Gopa Iyer Yelena Y Janjigian Emmet J Jordan Ciara M Kelly Maeve A Lowery Luc G T Morris Antonio M Omuro Nitya Raj Pedram Razavi Alexander N Shoushtari Neerav Shukla Tara E Soumerai Anna M Varghese Rona Yaeger Jonathan Coleman Bernard Bochner Gregory J Riely Leonard B Saltz Howard I Scher Paul J Sabbatini Mark E Robson David S Klimstra Barry S Taylor Jose Baselga Nikolaus Schultz David M Hyman Maria E Arcila David B Solit Marc Ladanyi Michael F Berger

Nat Med 2017 08;23(8):1004

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http://dx.doi.org/10.1038/nm0817-1004cDOI Listing
August 2017

OncoKB: A Precision Oncology Knowledge Base.

JCO Precis Oncol 2017 Jul 16;2017. Epub 2017 May 16.

, Marie-Josée and Henry R. Kravis Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA; , Gastrointestinal Oncology Service, Division of Solid Tumor Oncology, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA; , Gynecologic Medical Oncology Service, Division of Solid Tumor Oncology, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA; , Breast Medicine Service, Division of Solid Tumor Oncology, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA, Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA, Weill Cornell Medical College, New York, NY USA; , Breast Medicine Service, Division of Solid Tumor Oncology, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA; , Thoracic Oncology Service, Division of Solid Tumor Oncology, Department of Medicine, Memorial Sloan Kettering Cancer Center , New York, NY, USA, Weill Cornell Medical College, New York, NY USA; , Head and Neck Oncology Service, Division of Solid Tumor Oncology, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA; , , Department of Hematology and Oncology, Quest Diagnostics Nichols Institute, 33608 Ortega Highway, San Juan Capistrano, CA, 92675, USA; , Department of R&D and Bioinformatics, Quest Diagnostics Nichols Institute, 33608 Ortega Highway, San Juan Capistrano, CA, 92675, USA; , Head and Neck Oncology Service, Division of Solid Tumor Oncology, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA, Weill Cornell Medical College, New York, NY USA; , Melanoma and Immunotherapeutics Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA, Weill Cornell Medical College, New York, NY USA; , Gynecologic Medical Oncology Service, Division of Solid Tumor Oncology, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA; , Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA, Sarcoma Medical Oncology Service, Division of Solid Tumor Oncology, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY, USA, Weill Cornell Medical College, New York, NY USA; Genitourinary Oncology Service, Division of Solid Tumor Oncology, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA, Weill Cornell Medical College, New York, NY USA; , Developmental Therapeutics, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA, Sarcoma Medical Oncology Service, Division of Solid Tumor Oncology, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY, USA, Weill Cornell Medical College, New York, NY USA; , Gastrointestinal Oncology Service, Division of Solid Tumor Oncology, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA, Weill Cornell Medical College, New York, NY USA; , Department of Neurology, Memorial Sloan Kettering Cancer Center, New York, NY, USA; , Brain Tumor Center, Memorial Sloan Kettering Cancer Center, New York, NY, USA, Department of Neurology, Memorial Sloan Kettering Cancer Center, New York, NY, USA; , Department of Oncology and Internal Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA, Weill Cornell Medical College, New York, NY USA; , Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, USA; , Genitourinary Oncology Service, Division of Solid Tumor Oncology, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA , Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA; , Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA, Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA, Marie-Josée and Henry R. Kravis Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA, Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA; , Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA, Marie-Josée and Henry R. Kravis Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA, Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA; , Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA, Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA; , Marie-Josée and Henry R. Kravis Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA, Developmental Therapeutics, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA; , Breast Medicine Service, Division of Solid Tumor Oncology, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA, Developmental Therapeutics, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA, Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA, Weill Cornell Medical College, New York, NY USA; , Marie-Josée and Henry R. Kravis Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA, Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA, Genitourinary Oncology Service, Division of Solid Tumor Oncology, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA, Weill Cornell Medical College, New York, NY USA; , Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA, Marie-Josée and Henry R. Kravis Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA, Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

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https://www.researchgate.net/profile/Debyani_Chakravarty/pub
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http://ascopubs.org/doi/10.1200/PO.17.00011
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5586540PMC
http://dx.doi.org/10.1200/PO.17.00011DOI Listing
July 2017

Mutational landscape of metastatic cancer revealed from prospective clinical sequencing of 10,000 patients.

Authors:
Ahmet Zehir Ryma Benayed Ronak H Shah Aijazuddin Syed Sumit Middha Hyunjae R Kim Preethi Srinivasan Jianjiong Gao Debyani Chakravarty Sean M Devlin Matthew D Hellmann David A Barron Alison M Schram Meera Hameed Snjezana Dogan Dara S Ross Jaclyn F Hechtman Deborah F DeLair JinJuan Yao Diana L Mandelker Donavan T Cheng Raghu Chandramohan Abhinita S Mohanty Ryan N Ptashkin Gowtham Jayakumaran Meera Prasad Mustafa H Syed Anoop Balakrishnan Rema Zhen Y Liu Khedoudja Nafa Laetitia Borsu Justyna Sadowska Jacklyn Casanova Ruben Bacares Iwona J Kiecka Anna Razumova Julie B Son Lisa Stewart Tessara Baldi Kerry A Mullaney Hikmat Al-Ahmadie Efsevia Vakiani Adam A Abeshouse Alexander V Penson Philip Jonsson Niedzica Camacho Matthew T Chang Helen H Won Benjamin E Gross Ritika Kundra Zachary J Heins Hsiao-Wei Chen Sarah Phillips Hongxin Zhang Jiaojiao Wang Angelica Ochoa Jonathan Wills Michael Eubank Stacy B Thomas Stuart M Gardos Dalicia N Reales Jesse Galle Robert Durany Roy Cambria Wassim Abida Andrea Cercek Darren R Feldman Mrinal M Gounder A Ari Hakimi James J Harding Gopa Iyer Yelena Y Janjigian Emmet J Jordan Ciara M Kelly Maeve A Lowery Luc G T Morris Antonio M Omuro Nitya Raj Pedram Razavi Alexander N Shoushtari Neerav Shukla Tara E Soumerai Anna M Varghese Rona Yaeger Jonathan Coleman Bernard Bochner Gregory J Riely Leonard B Saltz Howard I Scher Paul J Sabbatini Mark E Robson David S Klimstra Barry S Taylor Jose Baselga Nikolaus Schultz David M Hyman Maria E Arcila David B Solit Marc Ladanyi Michael F Berger

Nat Med 2017 Jun 8;23(6):703-713. Epub 2017 May 8.

Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York, USA.

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http://www.nature.com/doifinder/10.1038/nm.4333
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http://dx.doi.org/10.1038/nm.4333DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5461196PMC
June 2017

Value in Colorectal Cancer Treatment: Where It Is Lacking, and Why.

Authors:
Leonard B Saltz

Cancer J 2016 May-Jun;22(3):232-5

From the Memorial-Sloan Kettering Cancer, New York, NY.

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http://dx.doi.org/10.1097/PPO.0000000000000194DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5543411PMC
January 2017

Reply to G. Le Flahec et al.

J Clin Oncol 2017 01 24;35(3):378. Epub 2016 Oct 24.

Zsofia K. Stadler and Leonard B. Saltz, Memorial Sloan Kettering Cancer Center, New York, NY.

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http://ascopubs.org/doi/10.1200/JCO.2016.69.9413
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http://dx.doi.org/10.1200/JCO.2016.69.9413DOI Listing
January 2017

Outcomes of ICU Admission of Patients With Progressive Metastatic Gastrointestinal Cancer.

J Intensive Care Med 2017 Jan 1:885066617748874. Epub 2017 Jan 1.

1 Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

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http://dx.doi.org/10.1177/0885066617748874DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6119510PMC
January 2017

Bevacizumab in colorectal cancer: it should have worked.

Authors:
Leonard B Saltz

Lancet Oncol 2016 11 19;17(11):1469-1470. Epub 2016 Sep 19.

GastroIntestinal Oncology Service, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S14702045163021
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http://dx.doi.org/10.1016/S1470-2045(16)30213-3DOI Listing
November 2016

Reliable Detection of Mismatch Repair Deficiency in Colorectal Cancers Using Mutational Load in Next-Generation Sequencing Panels.

J Clin Oncol 2016 06 28;34(18):2141-7. Epub 2016 Mar 28.

Zsofia K. Stadler, Francesca Battaglin, Sumit Middha, Jaclyn F. Hechtman, Christina Tran, Andrea Cercek, Rona Yaeger, Neil H. Segal, Anna M. Varghese, Diane L. Reidy-Lagunes, Nancy E. Kemeny, Erin E. Salo-Mullen, Asad Ashraf, Martin R. Weiser, Julio Garcia-Aguilar, Mark E. Robson, Kenneth Offit, Maria E. Arcila, Michael F. Berger, Jinru Shia, David B. Solit, and Leonard B. Saltz, Memorial Sloan Kettering Cancer Center, New York, NY; and Francesca Battaglin, Veneto Institute of Oncology, Padua, Italy.

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http://dx.doi.org/10.1200/JCO.2015.65.1067DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4962706PMC
June 2016

Genetic Screening in All Young Patients With Colorectal Cancer?

Authors:
Leonard B Saltz

J Clin Oncol 2016 05 29;34(13):1560. Epub 2016 Feb 29.

Memorial Sloan Kettering Cancer Center, New York, NY

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http://dx.doi.org/10.1200/JCO.2015.65.9847DOI Listing
May 2016

Determinants of Early Mortality Among 37,568 Patients With Colon Cancer Who Participated in 25 Clinical Trials From the Adjuvant Colon Cancer Endpoints Database.

J Clin Oncol 2016 Apr 8;34(11):1182-9. Epub 2016 Feb 8.

Winson Y. Cheung, British Columbia Cancer Agency, Vancouver, British Columbia; Chris O'Callaghan, Queen's University, Kingston, Ontario, Canada; Lindsay A. Renfro, Axel Grothey, Steven R. Alberts, and Daniel J. Sargent, Mayo Clinic, Rochester, MN; David Kerr, University of Oxford, Oxford; Chris Twelves, University of Leeds and St James Institute of Oncology, Leeds, United Kingdom; Aimery de Gramont, Franco-British Institute, Levallois-Perret; Thierry Andre, Hospital Saint-Antoine and Pierre and Marie Curie University, Paris; Jean-Francois Seitz, La Timone Hospital, Aix-Marseille University, Marseille, France; Leonard B. Saltz, Memorial Sloan Kettering Cancer Center, New York, NY; Katherine A. Guthrie, Fred Hutchinson Cancer Center, Seattle, WA; Roberto Labianca, Ospedale Giovanni XXIII, Bergamo; Guido Francini, University of Siena, Siena, Italy; Eric Van Cutsem, University Hospital Leuven, Leuven, Belgium; Daniel G. Haller, University of Pennsylvania, Philadelphia; and Greg Yothers, University of Pittsburgh, Pittsburgh, PA.

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http://dx.doi.org/10.1200/JCO.2015.65.1158DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933130PMC
April 2016

The Value of Considering Cost, and the Cost of Not Considering Value.

Authors:
Leonard B Saltz

J Clin Oncol 2016 Mar 14;34(7):659-60. Epub 2015 Dec 14.

Memorial Sloan Kettering Cancer Center, New York, NY

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http://dx.doi.org/10.1200/JCO.2015.64.7867DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569684PMC
March 2016

Overspending driven by oversized single dose vials of cancer drugs.

BMJ 2016 Feb 29;352:i788. Epub 2016 Feb 29.

Center for Health Policy and Outcomes, Memorial Sloan Kettering Cancer Center, 485 Lexington Avenue, New York, NY 10017, USA Department of Medicine, Memorial Sloan Kettering Cancer Center, New York.

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http://www.bmj.com/lookup/doi/10.1136/bmj.i788
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http://dx.doi.org/10.1136/bmj.i788DOI Listing
February 2016

Perspectives on Cost and Value in Cancer Care.

Authors:
Leonard B Saltz

JAMA Oncol 2016 Jan;2(1):19-21

Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.

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http://oncology.jamanetwork.com/article.aspx?doi=10.1001/jam
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http://dx.doi.org/10.1001/jamaoncol.2015.4191DOI Listing
January 2016

Body Mass Index Is Prognostic in Metastatic Colorectal Cancer: Pooled Analysis of Patients From First-Line Clinical Trials in the ARCAD Database.

J Clin Oncol 2016 Jan 26;34(2):144-50. Epub 2015 Oct 26.

Lindsay A. Renfro and Daniel J. Sargent, Mayo Clinic, Rochester, MN; Fotios Loupakis and Alfredo Falcone, Azienda Ospedaliero-Universitaria Pisana and Università di Pisa, Pisa, Italy; Richard Adams, Cardiff University, Cardiff; Matthew T. Seymour, St James's Hospital and University of Leeds, Leeds, United Kingdom; Volker Heinemann, University of Munich, Munich; Hans-Joachim Schmoll, University Clinic Halle (Saale), Halle; Rainer Porschen, Klinikum Bremen-Ost Klinik für Innere Medizin, Bremen; Carsten Bokemeyer, University Hospital Cancer Center, University Hospital, Hamburg-Eppendorf, Germany; Jean-Yves Douillard, Institut de Cancerologie, Centre René Gauducheau, Nantes; Christophe Tournigand, University of Paris Est Creteil, Henri-Mondor Hospital, Créteil; Benoist Chibaudel and Aimery de Gramont, Franco-British Institute, Levallois-Perret, France; Herbert Hurwitz, Duke University Medical Center, Durham, NC; Charles S. Fuchs, Dana-Farber Cancer Institute Boston, MA; Eduardo Diaz-Rubio, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos, Madrid, Spain; Niall C. Tebbutt, Austin Health, Heidelberg, Victoria, Australia; Cornelis J.A. Punt, Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands; J. Randolph Hecht, David Geffen School of Medicine at the University of California at Los Angeles; Heinz-Josef Lenz, University of Southern California/Norris Comprehensive Cancer Center, Keck School of Medicine, Los Angeles, CA; Eric Van Cutsem, University Hospital Leuven, Leuven, Belgium; Richard M. Goldberg, Ohio State University, Columbus, OH; and Leonard B. Saltz, Memorial Sloan-Kettering Cancer Center, New York, NY.

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http://dx.doi.org/10.1200/JCO.2015.61.6441DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5070548PMC
January 2016

Biologic agents in the treatment of colorectal cancer: the last decade; the lost decade?

Am Soc Clin Oncol Educ Book 2013

From the University of California, San Francisco, San Francisco, CA; Memorial Sloan-Kettering Cancer Center, New York, NY.

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http://dx.doi.org/10.1200/EdBook_AM.2013.33.e121DOI Listing
November 2015

Assessment of Clinical Complete Response After Chemoradiation for Rectal Cancer with Digital Rectal Examination, Endoscopy, and MRI.

Ann Surg Oncol 2015 Nov 1;22(12):3769-71. Epub 2015 Jul 1.

Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

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http://link.springer.com/content/pdf/10.1245/s10434-015-4691
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http://link.springer.com/10.1245/s10434-015-4691-0
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http://dx.doi.org/10.1245/s10434-015-4691-0DOI Listing
November 2015

Coffee Intake, Recurrence, and Mortality in Stage III Colon Cancer: Results From CALGB 89803 (Alliance).

J Clin Oncol 2015 Nov 17;33(31):3598-607. Epub 2015 Aug 17.

Brendan J. Guercio, Shuji Ogino, and Edward L. Giovannucci, Harvard Medical School; Kaori Sato, Robert J. Mayer, Shuji Ogino, Jeffrey A. Meyerhardt, and Charles S. Fuchs, Dana-Farber Cancer Institute; Frank B. Hu, Shuji Ogino, Kana Wu, Walter C. Willett, and Edward L. Giovannucci, Harvard T.H. Chan School of Public Health; Shuji Ogino and Edward L. Giovannucci, Brigham and Women's Hospital, Boston, MA; Leonard B. Saltz, Memorial Sloan Kettering Cancer Center, New York, NY; Rex B. Mowat, Toledo Community Hospital Oncology Program, Toledo, OH; Renaud Whittom, Hôpital du Sacré-Coeur de Montréal, Montreal, Quebec, Canada; Alexander Hantel, Loyola University Stritch School of Medicine, Naperville; Al Benson, Northwestern University; Hedy Kindler, University of Chicago, Chicago, IL; Daniel Atienza, Virginia Oncology Associates, Norfolk, VA; Donna Niedzwiecki and Xing Ye, Duke University Medical Center, Durham; Michael Messino, Southeast Cancer Control Consortium, Mission Hospitals, Asheville, NC; and Alan Venook, University of California at San Francisco Comprehensive Cancer Center, San Francisco, CA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4622099PMC
November 2015

Reply to A. Messori et al, R. Bordonaro et al, and G. Fasola et al.

Authors:
Leonard B Saltz

J Clin Oncol 2015 Nov 24;33(32):3843-4. Epub 2015 Aug 24.

Memorial Sloan Kettering Cancer Center, New York, NY

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http://dx.doi.org/10.1200/JCO.2015.62.9287DOI Listing
November 2015

Genomic Profiling of Cancers of Unknown Primary Site: The Next Steps.

JAMA Oncol 2015 Jul;1(4):541-2

Gastrointestinal Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.

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http://dx.doi.org/10.1001/jamaoncol.2015.0939DOI Listing
July 2015

MRE11-deficiency associated with improved long-term disease free survival and overall survival in a subset of stage III colon cancer patients in randomized CALGB 89803 trial.

PLoS One 2014 13;9(10):e108483. Epub 2014 Oct 13.

Department of Immunology, University of Washington, Seattle, Washington, United States of America; Molecular and Cellular Biology Graduate Program, University of Washington, Seattle, Washington, United States of America; Department of Pathology, University of Washington Medical School, Seattle, Washington, United States of America; Department of Biochemistry, University of Washington, Seattle, Washington, United States of America.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4195600PMC
June 2015

Liver-directed conversion therapy in metastatic colon cancer.

J Gastrointest Oncol 2015 Jun;6(3):322-8

1 Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA ; 2 Weill Cornell Medical College, New York, NY, USA ; 3 American University of Beirut, Beirut, Lebanon ; 4 National Guard Hospital at King Abdul-Aziz Medical City, Riyadh, Saudi Arabia.

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http://dx.doi.org/10.3978/j.issn.2078-6891.2015.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4397241PMC
June 2015

RAF plus EGFR Inhibition for BRAF-Mutant Metastatic Colorectal Cancer-Response.

Clin Cancer Res 2015 May;21(9):2188

Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.

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http://dx.doi.org/10.1158/1078-0432.CCR-15-0412DOI Listing
May 2015

The Cost and Value of Anti-Epidermal Growth Factor Receptor Therapies: Let's Not Be Rash.

Authors:
Leonard B Saltz

JAMA Oncol 2015 May;1(2):141-2

Gastrointestinal Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.

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http://dx.doi.org/10.1001/jamaoncol.2015.0287DOI Listing
May 2015

Can money really be no object when cancer care is the subject?

Authors:
Leonard B Saltz

J Clin Oncol 2015 Apr 17;33(10):1093-4. Epub 2015 Feb 17.

Memorial Sloan Kettering Cancer Center, New York, NY

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http://dx.doi.org/10.1200/JCO.2014.60.1401DOI Listing
April 2015

Colorectal cancer.

Authors:
Leonard B Saltz

Hematol Oncol Clin North Am 2015 Feb;29(1):ix

Memorial Sloan Kettering Cancer Center, 300 East 66th Street, New York, NY 10065, USA. Electronic address:

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http://dx.doi.org/10.1016/j.hoc.2014.10.012DOI Listing
February 2015

Aspirin and COX-2 inhibitor use in patients with stage III colon cancer.

J Natl Cancer Inst 2015 Jan 27;107(1):345. Epub 2014 Nov 27.

: Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA (KN, JAM, KS, JAC, RJM, SO, CSF); Division of Gastroenterology, Massachusetts General Hospital, Boston, MA (ATC); Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA (ATC, ELG, CSF); Alliance Statistics and Data Center, Duke University Medical Center, Durham, NC (DN); Memorial Sloan-Kettering Cancer Center, New York, NY (LBS); Division of Hematology/Oncology, Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, IL (ABB); Toledo Community Hospital Oncology Program, Toledo, OH (PLS); Hopital du Sacre-Coeur de Montreal, Universite de Montreal, Quebec, Canada (RW); Edward Cancer Center, Naperville, IL (AH); Division of Medical Oncology, The Ohio State University Comprehensive Cancer Center, Columbus, OH (RMG); Division of Medical Oncology, University of California at San Francisco, San Francisco, CA (APV); Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA (SO); Department of Epidemiology (SO, ELG) and Department of Nutrition (ELG), Harvard School of Public Health, Boston, MA.

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http://dx.doi.org/10.1093/jnci/dju345DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4271076PMC
January 2015

ACCENT-based web calculators to predict recurrence and overall survival in stage III colon cancer.

J Natl Cancer Inst 2014 Dec 29;106(12). Epub 2014 Oct 29.

Division of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, MN (LAR, DJS); Department of Oncology, Mayo Clinic, Rochester, MN (AMG, SRA, CLL); Department of Statistics, University of Virginia, Charlottesville, VA (YX); Gastrointestinal Oncology Service, Memorial Sloan-Kettering Cancer Center, New York, NY (LBS); Hôpital Saint Antoine, Paris, France; Pierre and Marie Curie University, Paris, France (TA); Leeds Institute of Cancer and Pathology, University of Leeds and St. James's University Hospital, Leeds Cancer Research UK Centre, UK (CT); Oncology Unit, Ospedale Giovanni XXIII, Bergamo, Italy (RL); Division of Hematology and Oncology, University of Florida, Gainesville, FL (CJA); National Surgical Adjuvant Breast and Bowel Project Biostatistical Center, Pittsburgh, PA (GY).

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http://jnci.oxfordjournals.org/cgi/doi/10.1093/jnci/dju333
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http://dx.doi.org/10.1093/jnci/dju333DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4334801PMC
December 2014

Ganetespib, a novel Hsp90 inhibitor in patients with KRAS mutated and wild type, refractory metastatic colorectal cancer.

Clin Colorectal Cancer 2014 Dec 21;13(4):207-12. Epub 2014 Sep 21.

Gastrointestinal Oncology Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY.

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http://dx.doi.org/10.1016/j.clcc.2014.09.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5489410PMC
December 2014

Management of metastatic colorectal cancer.

Authors:
Leonard B Saltz

Oncology (Williston Park) 2014 Oct;28(10):841-4, 894

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October 2014

Colorectal cancer survivors' needs and preferences for survivorship information.

J Oncol Pract 2014 Jul 3;10(4):e277-82. Epub 2014 Jun 3.

Memorial Sloan-Kettering Cancer Center; Queens Cancer Center of Queens Hospital, New York, NY; and Harvard School of Public Health, Boston, MA.

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http://dx.doi.org/10.1200/JOP.2013.001312DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4094649PMC
July 2014

Neoadjuvant chemotherapy first, followed by chemoradiation and then surgery, in the management of locally advanced rectal cancer.

J Natl Compr Canc Netw 2014 Apr;12(4):513-9

From the aGastrointestinal Oncology Service, Department of Medicine, bDepartment of Radiation Therapy, and cColorectal Surgery Service, Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, New York.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5612781PMC
April 2014

A phase II study of cixutumumab (IMC-A12, NSC742460) in advanced hepatocellular carcinoma.

J Hepatol 2014 Feb 14;60(2):319-24. Epub 2013 Sep 14.

Department of Internal Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY, United States; Department of Internal Medicine, Weill Medical College at Cornell University, New York, NY, United States.

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http://dx.doi.org/10.1016/j.jhep.2013.09.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3901953PMC
February 2014

Albumin-bound paclitaxel plus gemcitabine in pancreatic cancer.

N Engl J Med 2014 01;370(5):478

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http://dx.doi.org/10.1056/NEJMc1314761DOI Listing
January 2014

Predictive and prognostic analysis of PIK3CA mutation in stage III colon cancer intergroup trial.

J Natl Cancer Inst 2013 Dec 14;105(23):1789-98. Epub 2013 Nov 14.

Affiliations of authors: Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA (SO, XL, YI, MY, NJM, KN, RJM, JAM, CSF); Department of Pathology (SO), Channing Division of Network Medicine, Department of Medicine (DS, CSF), and Department of Surgery (MMB), Brigham and Women's Hospital and Harvard Medical School, Boston, MA (SO); Department of Epidemiology (SO, DS) and Department of Biostatistics (DS) , Harvard School of Public Health, Boston, MA; Alliance Statistics and Data Center, Duke University Medical Center, Durham, NC (DN); Memorial Sloan-Kettering Cancer Center, New York, NY (LBS); Hôpital du Sacré-Coeur de Montréal, Montreal, Canada (RW); Loyola University Stritch School of Medicine, Maywood, IL (AH); current: Edward Cancer Center, Naperville, IL (AH); Northwestern University, Chicago, IL (ABB); Toledo Community Hospital Oncology Program, Toledo, OH (RBM); Division of Medical Oncology, The Ohio State University Comprehensive Cancer Center, Columbus, OH (RMG).

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http://dx.doi.org/10.1093/jnci/djt298DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3848984PMC
December 2013

Colorectal cancer patients with oligometastatic liver disease: what is the optimal approach?

Oncology (Williston Park) 2013 Nov;27(11):1074-8

Colorectal Service/Dept. of Surgery, Memorial Sloan-Kettering Cancer Center, New York, New York 10065, USA.

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November 2013

Association of TP53 mutational status and gender with survival after adjuvant treatment for stage III colon cancer: results of CALGB 89803.

Clin Cancer Res 2013 Oct 27;19(20):5777-87. Epub 2013 Aug 27.

Authors' Affiliations: Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, California; Department of Biostatistics and Bioinformatics, Alliance Statistics and Data Center, Duke University Medical Center, Durham, North Carolina; Dana-Farber Cancer Institute; Dana-Farber Cancer Institute, Brigham and Women's Hospital, Boston, Massachusetts; The Ohio State University, Columbus, Ohio; National Cancer Institute, Bethesda, Maryland; and Memorial Sloan-Kettering Cancer Center, New York, New York.

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http://dx.doi.org/10.1158/1078-0432.CCR-13-0351DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4122229PMC
October 2013

Incidence of chemotherapy-induced amenorrhea in premenopausal women treated with adjuvant FOLFOX for colorectal cancer.

Clin Colorectal Cancer 2013 Sep 17;12(3):163-7. Epub 2013 Jul 17.

Division of Solid Tumor Oncology, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA.

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http://dx.doi.org/10.1016/j.clcc.2013.04.007DOI Listing
September 2013

Role of expression profiling in carcinoma of unknown primary remains unknown.

Authors:
Leonard B Saltz

J Clin Oncol 2013 Jul 3;31(19):2513-4. Epub 2013 Jun 3.

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http://dx.doi.org/10.1200/JCO.2013.49.2264DOI Listing
July 2013

Nonoperative management of rectal cancer with complete clinical response after neoadjuvant therapy.

Ann Surg 2012 Dec;256(6):965-72

Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA.

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http://dx.doi.org/10.1097/SLA.0b013e3182759f1cDOI Listing
December 2012